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1 tics that ancestral TEM-1 had been unable to deactivate.
2 ause these catalyst particles to permanently deactivate.
3 af auditory cortex, the dorsal zone (DZ), is deactivated.
4 channel to be either heat-activated or heat-deactivated.
5 s displaced from C1q, and the C1 complex was deactivated.
6 osphatase and tensin homolog (PTEN) has been deactivated.
7 prove when channels with high thresholds are deactivated.
8 In contrast, the triafulvenyl group is deactivating.
10 support a model whereby STIM1 is critical to deactivate a key negative regulator of cardiac hypertrop
11 tivate a TTX-sensitive Na(+) conductance and deactivate a resting Ih conductance, leading to a striki
13 sites, we also observed heterotopic effects; deactivating a specific domain in M1 (e.g., forelimb lif
14 equently, the same prefrontal cortical areas deactivated after a painful experience had been reached.
16 a), N(alpha)-dicarboxymethyllysine (NTA) and deactivating agents to block non-selective binding betwe
17 ladium-catalyzed three-component coupling of deactivated alkenes, arylboronic acids, and N-fluorobenz
19 ocortical population activity varies between deactivated and activated states marked by the presence
20 ting the topological role of edges between a deactivated and an activated node, we found that such co
21 pain, the medial prefrontal cortex (mPFC) is deactivated and mPFC-dependent tasks such as attention a
22 tained exposure, mitochondrial biogenesis is deactivated and uncoupling down-regulated, perhaps to im
23 ring dehydration and rehydration, C. pumilum deactivates and activates partial components of the phot
24 TP with high- and (d) low-threshold channels deactivated, and (e) MP with high- and (f) low-threshold
28 tion reactions with only 1.2 equiv activated/deactivated arenes (no additional solvent) to access str
31 patch currents activated rapidly (<1 ms) and deactivated as a function of the alpha-subunit, with alp
32 lay genetic interactions with mutations that deactivate astral microtubule-dependent nuclear migratio
35 urified by column chromatography; the use of deactivated basic alumina (activity IV) afforded high yi
36 nts had their left ventricular assist device deactivated before death, with all but 3 undergoing deac
39 The combined dataset suggests that TRX may deactivate both mitochondrial succinate dehydrogenase an
40 altered dynamics on a mus-ms time scale and deactivates both of the divalent cation-binding sites of
41 tween multiple open and closed states in non-deactivating bursts at positive membrane potentials.
42 are activated by a major pre-EMT marker and deactivated by a post-EMT marker, boosting the transitio
45 photoexcited acceptor state is predominantly deactivated by bimolecular electron transfer reactions (
49 Apratoxin S8 (1c) lacks the propensity to be deactivated by dehydration and showed efficacy in a huma
51 try composed of the regulator TnrA, which is deactivated by feedback-inhibited glutamine synthetase (
53 posed that the deacylating water molecule is deactivated by interaction with the carbapenem 6alpha-1R
54 avibactam, but not the bicyclic boronate is deactivated by L1 at a low rate; the utility of avibacta
55 g somatosensory areas can become extensively deactivated by lesions of somatosensory afferents as the
57 thalimide probe QMeNN, whose fluorescence is deactivated by photoinduced electron transfer (PeT) quen
58 d picomolar affinity for CB receptors and is deactivated by plasma esterases while the respective aci
59 switches in a family of hammerhead ribozymes deactivated by stem or loop replacement with a U-rich se
60 lite ZSM-5 crystal, which has been partially deactivated by the methanol-to-hydrocarbons reaction usi
61 nowledge of which pathways are activated and deactivated by these essential sensors is largely unknow
62 ntal gyrus (SFG) that was also sensitive to (deactivated by) demanding initial choices and another in
63 e and, therefore, like many other catalysts, deactivates by coking during reactions in hydrocarbon-ri
64 tions using RI-CC2/cc-pVDZ show that 5 in S1 deactivates by direct ESIPT from the OH to the naphthale
66 l for specific DNA methylation consisting of deactivated Cas9 (dCas9) nuclease and catalytic domain o
68 CRISPRi, in which a doxycycline-inducible deactivated Cas9 is fused to a KRAB repression domain, c
70 proaches to reduce pathogenesis by targeting deactivated Cas9 to either the DNA or the RNA repeats wi
71 tion of the sensor and kinase domains, which deactivates catalysis, increased the solvent exposure of
72 r the LQT2-causing mutation R56Q gave faster-deactivating channels that displayed an attenuated mode-
73 ich expressed the Cbfb-MYH11 fusion gene and deactivated Chd7 in hematopoietic cells upon inducing Cr
74 emonstrating that the formation of the first deactivating coke precursor molecules occurs in nanoscop
75 nd) and the evolution of active species into deactivating coke species have received less attention.
76 ase in MIF, in terms of a difference between deactivating collisions and what we term here "symmetry-
77 enia is associated with a reduced ability to deactivate components of default mode networks, followin
78 c in both hospital and community settings by deactivating conventional beta-lactam antibiotics, inclu
79 ain may rapidly and alternately activate and deactivate cortical areas advantageous or obtrusive to f
81 d that a dCas9-VP64 system consisting of the deactivated CRISPR-associated protein 9 (dCas9) fused wi
82 known about how to specifically capture and deactivate CTCs in vivo, which may lead to successful me
83 ligomers produce strongly desensitizing fast deactivating currents and nondesensitizing slowly deacti
87 hydrodynamic force in hemorrhage and rapidly deactivated downstream, providing a paradigm for hierarc
88 e excitation light photoactivates as well as deactivates Dronpa single molecules, hindering temporal
89 a collection of brain regions that reliably deactivate during goal-directed behaviors and is more ac
90 ocampal overactivity was due to a failure to deactivate during loss events in comparison to controls,
91 FTP network was activated during Speech and deactivated during Count and nonverbal Decision trials,
94 s requested that their devices be removed or deactivated during the study, although their reasons for
96 which a calcium chelating buffer effectively deactivates E-selectin so that leukocytes may be rinsed
99 e activation is demonstrated to overcome the deactivating effect of a trifluoromethyl substituent, ma
100 etal, such as ruthenium, for alleviating the deactivating effect of carbon monoxide, opening the door
101 eptor IIb, IL-10, and TGF-beta, had a potent deactivating effect on proinflammatory lipopolysaccharid
102 mined both of these hypotheses by surgically deactivating either the magnetic or olfactory sensory sy
103 lculates the likelihood of a genetic variant deactivating enhancers by disrupting the binding of tran
104 are tunable by regulating the levels of the deactivating enzyme and receptor, as well as by adjustin
106 with phosphatases, which dephosphorylate and deactivate ERK, and with substrates, which connect ERK t
109 -mediated blockade of NMDA receptors at rest deactivates eukaryotic elongation factor 2 (eEF2) kinase
110 onstrates that the clusters do not sinter or deactivate even after prolonged exposure to reactants at
111 ained, even when conducted on electronically deactivated, eventually also sterically hindered, substr
113 of FlrA to the promoter of the flrBC operon, deactivating expression of the flagellar biosynthesis re
114 ediated by alpha1(T47R)beta2gamma2 receptors deactivated faster than those mediated by alpha1beta2gam
115 s established by programming TFs are rapidly deactivated following Lhx3 downregulation in stem-cell-d
117 establishes that the particles do not become deactivated for the outer-sphere electron transfer react
123 The mass spectrometer was coupled via a deactivated fused silica capillary to an injector of a g
124 A well-defined restriction placed inside a deactivated fused silica capillary was used to increase
126 Regulator of G-Protein Signalling-1 (RGS1) deactivates G-protein signalling, reducing the response
127 revealed that the DNMT3a-deficient cells had deactivated gene networks involved in calcium, endotheli
128 by ectopic expression of a GA 2-oxidase (GA-deactivating) gene, consistent with GA(3) being protecte
131 a vertical Gabor patch moving away from the deactivated hemifield decreased prestimulus and stimulus
132 well as other electrophiles (e.g., hindered/deactivated/heterocyclic aryl iodides, an aryl bromide,
138 de that pathogenic leptospiral proteases can deactivate immune effector molecules and represent poten
139 ars ago) and show that as they activated and deactivated in different locations, their overall number
141 cture and photosystem genes were immediately deactivated in NR-KO cells following NO3(-) addition, fo
142 acute bacterial infection, T1R2/3 is likely deactivated in response to bacterial consumption of airw
143 at enhancers of fibroblast genes are rapidly deactivated in the absence of Kdm5b, and genes associate
145 dyl peptidase IV (DPPIV); an enzyme known to deactivate incretins, hormones involved in insulin secre
148 ng the M1 proinflammatory phenotype, thereby deactivating inflammatory responses in macrophages.
149 nase A (PKA)-activated and calcineurin (CaN)-deactivated inhibitor of protein phosphatase 1 (PP1).
151 activity is part of a 'timing mechanism' to deactivate IRE1 immediately following engagement of the
152 T1 interacts with and deacetylates PABP1 and deactivates its poly(A)RNA binding, leading to nuclear a
154 gomers produce moderately desensitizing fast deactivating K(+) currents, whereas KCTD12 and KCTD16 ho
157 ly active Rac1 at the cell edge, stathmin is deactivated locally, which establishes a spatial gradien
161 ified lipocalin 2 (LCN2) as both a marker of deactivated macrophages and a macrophage deactivator.
163 pressing cells with lumacaftor and ivacaftor deactivated macroscopic F508del-CFTR Cl(-) currents.
175 ssing differentiation of Th1 and Th17 cells, deactivating myeloid cells, inhibiting STAT activation i
176 challenging coupling reaction at the highly deactivated N-terminal position proved to be much more p
178 ry pathway in the upper cervical spinal cord deactivates neurons in the hand region in contralateral
180 zed by glucose oxidase and galactose oxidase deactivate nitrate reductase and must be quenched for bi
187 for hybridization to a probe, and they also deactivate other closely related sequences in solution.
196 eeps it enzymatically active by blocking its deactivating phosphorylation by Mst1, a serine/threonine
197 On the other hand, the proposed existence of deactivating polar effects at the alpha-position in Cl(*
199 od using proteinase K followed by heating to deactivate proteins and for safe injections into mice.
200 genic bacteria and eukaryotic host organisms deactivate Rab GTPases by supplying catalytic arginine a
201 e 1-position, the singlet excited states are deactivated rapidly before electron transfer can occur,
203 EPSCs cause the activated T-type channels to deactivate rather than inactivate, enabling repetitive a
206 plate tangential cells can be activated and deactivated repeatedly with no evident change in depolar
207 tive dusk" genes and that its overexpression deactivates rhythmic gene expression without significant
208 n of Akt after 2 h of hypoxic exposure might deactivate RNA-binding protein BRF1, hence resulting in
210 r, and in cases where the donor is otherwise deactivated, several examples of moderate diastereoselec
211 of eliciting signals which both activate and deactivate signaling for increased cytokine/chemokine pr
213 talysis is determined to be CO loss from the deactivated species, [Ni(cyclam)(CO)](+), to produce the
216 that JZTx-27 stabilized the NsVBa VSM in the deactivated state and may be used as a probe to determin
217 cing modifies the return from inactivated to deactivated states, and the differences between splice v
218 ely to form a disulfide in the activated and deactivated states, relative immobilization by crosslink
222 interaction, focusing electrical fields, and deactivating subsets of channels were assessed by the ch
224 te is enabled by the solvent polarity: It is deactivated/switched-off in apolar toluene, while in pol
225 eath-1 (PD-1) with PD-1-ligand-1 (PD-L1) to "deactivate" T cell functions, but the role of PD-L2 rema
227 ydrodibenzo[a,e][8]annulene and irreversibly deactivate the diamagnetic molybdenum metallacyclobutadi
229 P-5), which are known to dephosphorylate and deactivate the senescence-inducing MAPK p38alpha, belong
231 e (TiPARP) gene expression, depleted NAD(+), deactivated the mitochondrial sirtuin deacetylase 3 (Sir
233 s when processing conflict, control subjects deactivated the posterior cingulate cortex (PCC), wherea
234 n the proportion of patients for whom the GP deactivated the template (33.6% [intervention] versus 27
235 ctivated the fronto-parietal WM networks and deactivated the typical DMN in response to increasing ta
236 ecular hydrogen bond in 1 and 2 and strongly deactivates the alpha-C-H bonds of the three substrates.
237 al ion binding to amines and amides strongly deactivates the C-H bonds of these substrates toward HAT
238 gen to Pt or Cu; and (iii) it electronically deactivates the C-H bonds proximal to the nitrogen cente
239 -ligase midline-1 (MID1), which binds to and deactivates the catalytic subunit of protein phosphatase
241 ad to an immediate unfolding but immediately deactivates the enzyme through a combination of subtle s
243 ed-state proton transfer (ESPT) process that deactivates the excited state in competition with fluore
245 These results indicate that HSP60 silencing deactivates the mTOR pathway to suppress glioblastoma pr
250 n kinases that respond to cellular stress by deactivating the eukaryotic initiation factor 2 alpha (e
254 found that water has a deleterious effect by deactivating the Ni catalyst via formation of a new Ni-b
256 that SBI-477 stimulated insulin signaling by deactivating the transcription factor MondoA, leading to
257 implicitly providing a handle for activating/deactivating the very first step in the redox chain.
259 damaged molecules in the nucleotide pool and deactivating them before they are incorporated into chro
260 al pathways shape PIT response properties by deactivating them while monitoring PIT activity in two m
261 ate encoding new intentions and subsequently deactivating them, and consider links between the model'
262 ivation ensures that T-type channels rapidly deactivate, thereby limiting inactivation during repetit
263 roduced during the autoxidation are shown to deactivate these more basic RTAs, the addition of a sacr
264 /temporal activation in control subjects but deactivated these regions in MDD, with opposite effects
265 electron deficiency of the amide C-H bonds, deactivating these bonds toward HAT to an electrophilic
268 serine-threonine protein phosphatase 1 (PP1) deactivates this pathway whereas prolonging eIF2alpha ph
270 tion revealed that the ruthenium catalyst is deactivated through the formation of a stable ruthenium-
271 The excited-state CH3O intermediate further deactivates through a seam of intersection between the g
272 pathogenic bacterium Yersinia enterocolitica deactivates TLR-induced signaling pathways, which trigge
274 assay in the device, wherein fluid flow was deactivated to allow individual reaction steps to go to
276 l electrode of the circular MER catheter was deactivated to prevent inadvertent bipolar radiofrequenc
279 ys across tissue and sex, upstream activated/deactivated transcription factors were first predicted f
280 that induction of glutathionylation not only deactivates UCP2-mediated proton leak but also enhances
283 active in the non-emissive quinone form and deactivated upon reduction to the emissive dihydroquinon
286 nt scavengers than quercetin itself, able to deactivate various free radicals, under different biolog
293 uble-stranded DNAs, the modified DNAzyme was deactivated when the uracil at the indispensable thymidi
294 hich contain the residues encoded by exon 5, deactivate with a dual exponential time course described
296 the DLPFC activation, and progressively more deactivated with increasing attention load in controls,
297 vinyl monomers are efficiently activated and deactivated with light leading to excellent control over
298 pulse of glutamate (1 ms), mutant receptors deactivated with significantly slower kinetics than wild
299 at for exon 5-lacking GluN1-1a/GluN2D, which deactivates with a tauFAST of 1100 ms and a tauSLOW of 3
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