ライフサイエンスコーパス: decapeptide

1 esion mechanism that can be modulated by the decapeptide.

2 nd 4, but not exon 2, which encodes the GnRH decapeptide.

3 myxin B (PxB), a cationic amphipathic cyclic decapeptide.

4 and become almost the same for the octa- and decapeptide.

5 hown for the solid-phase assembly of the ACP decapeptide.

6 extracellular medium as a cleaved, modified decapeptide.

7 ishing the releasable pool of this essential decapeptide.

8 d EdTx, and binding to solid-phase LF and EF decapeptides.

9 utation in the eighth amino acid of the GnRH decapeptide, 1 nonsense mutation that causes premature t

10 A decapeptide 18-4a (NH(2)-WxEAAYQkFL-CONH(2)) [corrected]

11 for k(cat) for H-D-Phe-L-Pip-Arg-pNA and the decapeptide (2a) are most consistent with two identical

12 atory actions in vivo and that the ubiquitin-decapeptide 50-59 has immunosuppressive effects similar

13 ith the full-size Abeta protein (Abeta42), a decapeptide Abeta(14-23) and alpha-synuclein; all three

14 Applications to assembly of the model decapeptide ACP showed that HDATU was far more effective

15 mical labeling of the tripeptide LWL and the decapeptide ACTH 1-10 with amine-containing reagents.

16 mbinant C5a and to a conformationally biased decapeptide agonist of C5a (YSFKPMPLaR) by releasing IL-

17 A conformationally biased decapeptide agonist of human C5a anaphylatoxin (YSFKPMPL

18 A conformationally biased decapeptide agonist of human C5a anaphylatoxin (YSFKPMPL

19 (AII) is proteolytically processed from the decapeptide AI by angiotensin-converting enzyme (ACE), a

20 using MALDI TOF mass spectrometry, oxidized decapeptides all showed evidence of multimer formation a

21 1/9/11/9/11/16/9/12/10" H-bonding, while the decapeptide ("alpha-beta-alpha-beta-alpha-beta-delta-alp

22 The decapeptide ("alpha-beta-alpha-beta-alpha-beta-gamma-alp

23 -Ser-Tyr-Hyp-Hyp-Thr-DOPA-Lys (mPEG-MAPD), a decapeptide analogue of a protein found in Mytilus eduli

24 The highly conserved NK decapeptide and homeodomain regions were identical betwe

25 ptide linkage between the MccE492 C-terminal decapeptide and monoglycosylated enterobactin (MGE) requ

26 upt the 3 C-terminal amino acids of the GnRH decapeptide and to produce a premature stop codon was id

27 sor; Ps4, a prepro-TRH-derived TRH-enhancing decapeptide, and EEP (pGlu-Glu-Pro-NH(2)).

28 tely 92 kDa) and number of tandemly repeated decapeptides, and contained the same post-translational

29 Here an analysis of back-exchange in the decapeptide, angiotensin I, and a hexapeptide derived by

30 rtion of this prototypical second generation decapeptide antagonist can be replaced with a more compa

31 , the first amino acid incorporated into the decapeptide antibiotic gramicidin S.

32 Starting from the cyclic decapeptide antibiotic tyrocidine A, this chemoenzymatic

33 f a decapeptide thioester to form the cyclic decapeptide antibiotic tyrocidine A.

34 The cyclic decapeptide antibiotic tyrocidine has D-Phe residues at

35 We wanted to test the effect of a synthetic decapeptide antimicrobial, KSL, on the development of or

36 only two residues (one near each end of the decapeptide) are critical for cyclization.

37 A synthetic decapeptide based on this sequence but with the N- and C

38 A fluorescently labeled wild-type BACH1 decapeptide (BDP1) containing the critical phosphoserine

39 MccE492 C-terminal decapeptides bearing fluorescein and biotin moieties on

40 presence of liquid plasma yielded two cyclic decapeptides, CGLIIQKNEC (CLT1) and CNAGESSKNC (CLT2).

41 Here we screen a decapeptide combinatorial library arranged in a position

42 ons of decapeptides with all the millions of decapeptides contained in a protein database to rank and

43 The two proteins are connected by a decapeptide containing a protease recognition site speci

44 tion, we examine the folding of a homologous decapeptide containing an amino acid substitution linked

45 determined, each in complex with a hepta- or decapeptide corresponding to a natural or nonnatural PTS

46 polycations such as spermine and a cationic decapeptide derived from SV40 T-antigen were only modera

47 Kisspeptin-10 (Kp-10), a decapeptide derived from the primary translation product

48 s studies allowed the identification of 4N1K decapeptide derived from the TSP-1/CD47 binding epitope.

49 Decapeptides derived from human HLA class I sequences ha

50 increases the rate of isomerization of three decapeptides derived from the N terminus of yeast histon

51 ead compound in a series of immunomodulating decapeptides discovered through activity-based screening

52 library, we demonstrated previously that the decapeptide DWEYSVWLSN is specifically bound by the path

53 approximately 36 tandemly repeated His-rich decapeptides (e.g., HVHTHRVLHK) in the N-terminal half a

54 munochemistry of these proteins, overlapping decapeptides encompassing the whole protein were synthes

55 Lysine decapeptides enhance RPR function by promoting holoenzym

56 GnRH is a multifunctional decapeptide essential for the development of secondary s

57 nworm, Manduca sexta, including the amidated decapeptide F10.

58 ; (iii) in water with a reduced density, the decapeptide forms a helix, indicating the sensitivity of

59 des a homeobox, an NK-2 box and a N-terminal decapeptide found in other Nk family members.

60 nd CHCA, is developed to directly sequence a decapeptide from a single cerebral ganglion B cell.

61 embrane using a dual-acylated amino-terminal decapeptide from Fyn is sufficient to restore the growth

62 a chimeric protein containing the N-terminal decapeptide from human group IIA PLA(2) joined with a (1

63 he glutamic acid of position 1 in the cyclic decapeptide G1TE, which is a potent inhibitor of tyrosin

64 ecognized the FITC-labeled LRAHAVDVNG-NH2, a decapeptide generated from the EC-1 domain of N-cadherin

65 mmortalized GT1-1 neurons, which secrete the decapeptide GnRH in a pulsatile manner conceptually iden

66 Insights into the active conformation of the decapeptide gonadotropin releasing hormone (GnRH) have b

67 The decapeptide gonadotropin-releasing hormone (GnRH) plays

68 The decapeptide gonadotropin-releasing hormone (GnRH), which

69 The hypothalamic decapeptide gonadotropin-releasing hormone stimulates mo

70 The hypothalamic decapeptide, gonadotropin-releasing hormone (GnRH), util

71 PSs which biosynthesize the symmetric cyclic decapeptide gramicidin S and the cyclic lipoheptapeptide

72 rences to scale the membrane affinity of the decapeptide Gramicidin S cyclo(d-Phe-Pro-Val-Orn-Leu-)2

73 e presented for the two charge states of the decapeptide Gramicidin S.

74 ha-thrombin bound to the factor XIII-(28-37) decapeptide has been determined.

75 Tandem mass spectrometry of isolated tryptic decapeptides has detected both C(2)-hexosylated tryptoph

76 Hexa- and decapeptides have been identified with sequence homologi

77 source of the immunodominant and protective decapeptide HF10 presented by the H-2L(d) major histocom

78 termine the self-assembled structures of the decapeptide hIAPP(20-29), which is considered to be the

79 co mosaic virus (TMV) virion with a mosquito decapeptide hormone, trypsin-modulating oostatic factor

80 in the Val-24-Lys-28 region of the wild-type decapeptide; (ii) in the presence of salt ions, salt bri

81 ce of either anti-E-cadherin antibody or the decapeptide in the assay medium.

82 eproduction in mammals by secreting the GnRH decapeptide into the portal blood vessels of the pituita

83 The conformation of the decapeptide is an Omega-loop.

84 We find that: (i) when the decapeptide is in water, hydrophobic interactions and tr

85 We find that the incorporated amphiphilic decapeptide is indeed helical.

86 uman group IB PLA(2) in which the N-terminal decapeptide is joined with the (13)C-labeled fragment, a

87 This MC1R hAGRP(109-118) based decapeptide is novel in that AGRP(83-132) itself does no

88 ation of cell-cell adhesion in BBMECs by the decapeptide is thought-provoking for creating channels f

89 This decapeptide (KKERKLARTA) is a fragment of the cardiac di

90 However, we found that true peptide bonds in decapeptide libraries were cleaved by the T1S mutant 10-

91 subsequently bioparmed against the original decapeptide library, the sole clone demonstrating inhibi

92 n the conserved cytochrome P450 heme-binding decapeptide loop resulted in the amplification of four c

93 ns of mouse dorsal root ganglia, Cat-S and a decapeptide mimicking the Cat-S-revealed tethered ligand

94 ted, and the minimal epitope was mapped to a decapeptide NS3-1J (10.4).

95 ing human secretory component to overlapping decapeptides of Calpha3, we confirm these residues and a

96 Decapeptides of prohevein were synthesized on derivatize

97 Probing an array of overlapping decapeptides of Rattus norvegicus (Rat) Krp1 with recomb

98 s I molecules of H-2d,u,p,q presented the V3 decapeptide P18-I10 (RGPGRAFVTI) to CTL.

99 an anti-GXM antibodies, we screened a random decapeptide phage display library with the human anti-GX

100 riants revealed a highly conserved consensus decapeptide PKISYPPTYK that is repeated 64 times and dif

101 Screening of L- and D-decapeptide positional scanning combinatorial peptide li

102 The hydroxylation of tyrosines in the decapeptide proceeds sequentially.

103 s observed during tyrosinase incubation of a decapeptide related to the mussel adhesive protein mefp1

104 tryptophan-rich domain of Pvfp-1 contains 42 decapeptide repeats with the consensus sequences ATPKPW(

105 r its ability to liberate the amino-terminal decapeptide required for formation of a functional SakST

106 udied Abeta monomer folding and identified a decapeptide segment of Abeta, (21)Ala-(22)Glu-(23)Asp-(2

107 we probe the initial stages of folding of a decapeptide segment of Abeta, Abeta(21-30), shown experi

108 Additionally, this decapeptide sequence attenuated complement-dependent VCA

109 conserved, vertebrate-specific non-enzymatic decapeptide sequence in the luminal stem domain plays a

110 The N-terminal decapeptide sequence of protease IV is not homologous wi

111 sterase (anti-AChE10S) and (b) the identical decapeptide sequence phosphorylated at the active site s

112 yclonal antibodies were generated from (a) a decapeptide sequence that includes the active site serin

113 , PC5/6, PC7, and PACE4 in cleaving over 100 decapeptide sequences representing the R-X-(R/K/X)-R dow

114 hbor and near-neighbor amino acid pairs into decapeptide sequences that are flanked by unique dipepti

115 Furthermore, the 4-Cpa-containing cyclic decapeptide shows remarkable selectivity in the inhibiti

116 ct is interpreted using a model of the 5A/5B decapeptide substrate bound to the active site of the NS

117 lex also accepts and modifies the C-terminal decapeptide substrate fragments of the structurally rela

118 Using a Bid decapeptide substrate, we observed that phosphorylation

119 on has been characterized in crystals of the decapeptide t-butoxycarbonyl-Leu-Val-beta Phe-Val-(D)Pro

120 e specific enrichment of two phage-displayed decapeptides, TAASGVRSMH and LTLRWVGLMS.

121 em that replaces the gene III protein with a decapeptide tag for immunologic quantitation.

122 sequence analysis, BZAP45 contains a unique decapeptide that is part of a putative leucine-zipper pr

123 c gonadotropin-releasing hormone (GnRH) is a decapeptide that stimulates pituitary synthesis and secr

124 Nine additional decapeptides that contained the same capping groups on t

125 lized further through the use of overlapping decapeptides that spanned this 26-mer.

126 We identified more than 100 decapeptides that stimulate these T cells at nanomolar c

127 NRPS catalyzes head-to-tail cyclization of a decapeptide thioester to form gramicidin S, and the TE d

128 wn to catalyze head-to-tail cyclization of a decapeptide thioester to form the cyclic decapeptide ant

129 By systematically varying the decapeptide-thioester substrate and comparing cyclizatio

130 etase efficiently catalyses cyclization of a decapeptide-thioester to form the antibiotic tyrocidine

131 We have been employing cyclic decapeptides to identify the determinants for substrate

132 cture-function studies of the hAGRP(109-118) decapeptide, Tyr-c[Cys-Arg-Phe-Phe-Asn-Ala-Phe-Cys]-Tyr-

133 urn of the cyclic beta-hairpin antimicrobial decapeptide tyrocidine A, (Tyrc A) was substituted with

134 responsible for the production of the cyclic decapeptide tyrocidine A, TycC TE, retains autonomous ab

135 Using a thioesterase domain from the decapeptide tyrocidine synthetase, 13 head-to-tail cycli

136 third DNA binding motif using the "AT hook" decapeptide unit (Lys(1)-Arg(2)-Prol(3)-Arg(4)-Gly(5)-Ar

137 Large cyclic decapeptides (up to 50-atom ring) were synthesized effic

138 A concentration-dependent binding of this decapeptide was also observed in the flow cytometry assa

139 A library of Ac-XXXXXPAPRM decapeptides was prepared on a TentaGel solid support us

140 A bacteriophage library displaying random decapeptides was used to characterize the binding prefer

141 terestingly, three copies of a tyrosine-rich decapeptide were found interspersed in the RGG box regio

142 Six natural or synthetic variants of this decapeptide were subjected to oxidation by tyrosinase or

143 The closely related decapeptides were labeled with the NIR dye, separated us

144 Gonadotropin-releasing hormone (GnRH) is a decapeptide widely known for its role in regulating repr

145 of a synthetic peptide based on the His-rich decapeptide with Fe3+, Co2+, Ni2+, Zn2+, and Cu2+ indica

146 des at the C-terminus provided access to the decapeptides with "hybrid HTH" motifs.

147 rom these libraries composed of trillions of decapeptides with all the millions of decapeptides conta

148 Decapeptides with Pro(3) modified to trans-4-hydroxyprol

149 the library (17(5) approximately 1.4 x 10(6) decapeptides) with a Lyme monoclonal antibody (H9724) an

150 ide (GAP), which lies C-terminal to the GnRH decapeptide within the GnRH precursor, and 2 sequence va

151 usly reported linear breast cancer targeting decapeptide WxEAAYQkFL, here we report the synthesis of

152 e minimal fission yeast CTD coding unit is a decapeptide Y(1)S(2)P(3)T(4)S(5)P(6)S(7)Y(1)S(2)P(3) and