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1 se, 2-oxoglutarate dehydrogenase and glycine decarboxylase).
2 lipoylation of the photorespiratory glycine decarboxylase.
3 pression level of Cmoxdc1 coding for oxalate decarboxylase.
4 uccinate than the pathway via 2-oxoglutarate decarboxylase.
5 t demonstrated for the classical MVA pathway decarboxylase.
6 nd characterization of any phosphomevalonate decarboxylase.
7 D1R, D2R, AMPAR, GABA(B)R and glutamic acid decarboxylase.
8 n be used by a parasite that lacks ornithine decarboxylase.
9 ehydrogenase and a subsequent glutaconyl-CoA decarboxylase.
10 synthesized putrescine via a SpeC ornithine decarboxylase.
11 synthase reaction involves a glycyl radical decarboxylase.
12 70 interacts with TH and aromatic amino acid decarboxylase.
14 ed conditional null alleles of Glutamic acid decarboxylase 1 (Gad1) and Resistant to dieldrin (Rdl),
15 enic mouse lines that suppress glutamic acid decarboxylase 1 (GAD1) in either cholecystokinin (CCK)-
16 used by epigenetic upregulation of glutamate decarboxylase 1 (GAD1), a regulator of the GABA neurotra
17 a-aminobutyric acid (GABA) and glutamic acid decarboxylase 1 (GAD1), the enzyme that synthesizes GABA
18 ), which is a suicide inhibitor of ornithine decarboxylase 1 (ODC1), and diethylnorspermine (DENSpm),
24 ynaptosomal-associated protein 29, glutamate decarboxylase 1, metabotropic glutamate receptor 1, and
25 n antizyme-mediated degradation of ornithine decarboxylase-1 and a resulting reduction in cellular po
26 to endosomes, and decarboxylation by PtdSer decarboxylase 2 (Psd2p) to produce phosphatidylethanolam
27 ne released from neurons expressing tyrosine decarboxylase 2 (Tdc2) signal directly to astrocytes to
28 In contrast, the silencing of glutamic acid decarboxylase 2-positive interneurons, which include the
29 ed autoantigens [proinsulin or glutamic acid decarboxylase 65 (GAD)] delayed T1D onset, but published
32 ed, including orexin cells and glutamic acid decarboxylase 65 (GAD65) cells, but their interplay in o
33 on cerebellar ataxia (CA) with glutamic acid decarboxylase 65 antibodies (GAD65-Abs) is based on case
34 globulin, and the autoantigens glutamic acid decarboxylase 65, heat shock protein 60, and tyrosine ph
35 diabetes-related autoantigens (glutamic acid decarboxylase 65, insulin, heat shock protein 60, and ty
36 rologic study results revealed glutamic acid decarboxylase 65-IgG in all cases (median value, 754 nmo
37 4 classic; 5 variant; 66% were glutamic acid decarboxylase 65-IgG positive) and 1 with progressive en
38 (PMP) antibody positivity; and glutamic acid decarboxylase 65-kDa isoform (GAD65) antibody positivity
39 cond GABA-synthesizing enzyme, glutamic acid decarboxylase 65-kDa isoform (GAD65), remains unclear.
40 ssenger RNA interference targeting glutamate decarboxylase 65/67 (GAD65/67) gene expression in the nu
41 lsed with preproinsulin (PPI), glutamic acid decarboxylase (65-kDa isoform; GAD65), and insulinoma-as
42 expression of GABAergic marker glutamic acid decarboxylase 67 (GAD67) and the number of GABAergic GAD
44 sion levels of parvalbumin and glutamic acid decarboxylase 67 (GAD67) in schizophrenia subjects but n
45 istently found lower levels of glutamic acid decarboxylase 67 (GAD67) messenger RNA (mRNA) in the pre
46 f the GABA-synthesizing enzyme glutamic acid decarboxylase 67-kDa isoform (GAD67) in the PFC have bee
47 ytochemical markers, including glutamic acid decarboxylase-67 (GAD67), somatostatin, and neuropeptide
48 lpha-amino-beta-carboxymuconic--semialdehyde decarboxylase, a class III amidohydrolase, with a single
49 o C12 and C18 are decarboxylated by sirohaem decarboxylase, a heterodimeric enzyme composed of AhbA a
50 chanisms, with reduced aromatic L-amino acid decarboxylase (AAAD) activity closely related to the app
54 ygous mutations in the aromatic l-amino acid decarboxylase (AADC) gene result in a severe depletion o
55 containing the enzyme aromatic l-amino acid decarboxylase (AADC) occur not only near the central can
56 o its decarboxylation by aromatic amino acid decarboxylase (AADC), an enzyme overexpressed in these m
57 sine hydroxylase (TH), aromatic l-amino acid decarboxylase (AADC), and GTP cyclohydrolase I (GCH1) tr
58 lly express the enzyme aromatic L-amino acid decarboxylase (AADC), which synthesizes trace amines dir
61 te with enhanced aconitase and cis-aconitate decarboxylase activities by controlling the expression o
62 The recombinant Slr1099 protein displayed decarboxylase activity and catalyzed in vitro the decarb
66 the recombinant Sll0936 protein did not show decarboxylase activity regardless of the conditions used
73 dc1 is solely responsible for the reversible decarboxylase activity, and that it requires a new type
74 ved to be initiated by a change in glutamate decarboxylase activity, but the underlying mechanisms ar
77 permidine biosynthesis: S-adenosylmethionine decarboxylase (AdoMetDC) and spermidine synthase (SpdSyn
78 s of Trypanosoma brucei S-adenosylmethionine decarboxylase alone and in functional complex with its c
79 pyruvoyl cofactor of S-adenosyl-L-methionine decarboxylase (AMD1) is dynamically controlled by intrac
80 glycyl radical enzyme 4-hydroxyphenylacetate decarboxylase, an enzyme involved in the fermentative pr
81 made possible by the evolution of a pyruvate decarboxylase, analogous to that in brewer's yeast and t
82 ways for polyamine biosynthesis via arginine decarboxylase and agmatinase were activated to rescue co
83 dE resulted in very high levels of glutamate decarboxylase and almost complete protection against aci
84 mtPE by RNAi silencing of phosphatidylserine decarboxylase and chronic reduction of mtPE in PSB-2 cel
85 lso analyzed the expression of the Histidine decarboxylase and ECP by flow cytometry and fluorescence
86 patients express higher levels of histidine decarboxylase and ECP than those from healthy volunteers
87 in H. volcanii of both the phosphomevalonate decarboxylase and isopentenyl phosphate kinase reactions
88 e show that cholangiocytes express histidine decarboxylase and its inhibition reduces CCA growth.
89 ania donovani have shown that both ornithine decarboxylase and spermidine synthase, two enzymes of th
90 4-mutant cells expressed high levels of DOPA decarboxylase and the dopamine transporter, two markers
91 g of 6-[(18) F]fluorodopa (FD; reflects dopa decarboxylase) and [(11) C]dihydrotetrabenazine (DTBZ; r
92 ichia coli induce expression of CadA (lysine decarboxylase) and CadB (lysine/cadaverine antiporter) i
93 rt (73%, P<0.01), the abundance of ornithine decarboxylase, and nitric oxide synthase (NOS3) proteins
94 Autoantibodies to insulin, glutamic acid decarboxylase, and the insulinoma-associated-2 (IA-2) mo
95 through the pro-tumorigenic enzyme ornithine decarboxylase, and this flux increases 2-fold following
96 Four patients also had high glutamic acid decarboxylase antibodies (>1000 U/ml), and one had high
97 y, many patients with SPS have glutamic acid decarboxylase antibodies (GAD-ab), but these 2 disorders
99 espite the persistence of anti-glutamic acid decarboxylase antibodies following auto-HSCT suggests th
101 ornithine and polyamine synthesis, ornithine decarboxylase appeared to be the rate-limiting enzyme fo
102 Arginase, arginine deiminase and arginine decarboxylase are potential enzymes that may be used for
104 syltransferase and orotidine-5-monophosphate decarboxylase, are fused in a multi-domain enzyme and ar
105 A (CoA) transferase, and YfdU, an oxalyl-CoA decarboxylase, are required for the adaptation effect bu
106 techols, employing 3,4-dihydroxybenzoic acid decarboxylases (AroY) that belong to the UbiD enzyme fam
107 rom incomplete catalysis by TpcK (a putative decarboxylase), as its deletion results in a nearly 10-f
109 8)F]FMT; a substrate for aromatic amino acid decarboxylase), baseline D2/3 receptor-binding potential
113 of triarylmethanols, and (3) benzoylformate decarboxylase-catalyzed enantioselective benzoin condens
116 e 4-phosphate dehydrogenase (PdxA) oxidative decarboxylase, class II aldolase, or ribulose 1,5-bispho
118 dC imports Glu into the cytoplasm, where Glu decarboxylases consume a cytoplasmic proton, which ends
124 l-carbidopa, which is known to inhibit DOPA decarboxylase (DDC), a key protein in Parkinson's diseas
125 identified one dopamine synthesis gene, DOPA decarboxylase (DDC), as a suppressor of tau toxicity in
126 uences of tyrosine hydroxylase (TH) and dopa decarboxylase (DDC), two key enzymes in the biosynthesis
127 in, and trace amines, relies in part on DOPA decarboxylase (DDC, AADC), an enzyme that is required fo
130 house assay for PGD of aromatic L-amino acid decarboxylase deficiency, based on an amplification refr
132 congeners originates from the activity of a decarboxylase-dehydrogenase enzyme with high similarity
133 , low levels of PE in the phosphatidylserine decarboxylase deletion mutant (psd1Delta) cause decrease
134 (a-FMHis), a suicide inhibitor of histidine decarboxylase, displayed impaired IA memory when tested
135 he polyamine biosynthetic pathway, ornithine decarboxylase, diverting the iNOS substrate l-arginine t
136 idoxal phosphate (PLP)-dependent l-aspartate decarboxylase encoded by MJ0050, the same enzyme that wa
138 t through direct activation of glutamic acid decarboxylase enzyme isoforms that convert glutamate to
140 atidylserine catalyzed by phosphatidylserine decarboxylase enzymes (PSD) as a suitable target for dev
141 POMC neurons, as these encode the glutamate decarboxylase enzymes GAD67 and GAD65, respectively.
142 Deltasll1981 strain, lacking 2-oxoglutarate decarboxylase, exhibited a succinate level that was 60%
144 line expressing cre recombinase in histidine decarboxylase-expressing neurons (Hdc-Cre) followed by a
145 and a subsequent decrease of both ornithine decarboxylase expression and polyamine levels, accompani
146 at members of the beta-hydroxyacid reductive decarboxylase family employ different active site featur
148 cterization studies of a novel phenylacetate decarboxylase from an anaerobic, sewage-derived enrichme
151 i xylonate dehydratase (yjhG), a 2-keto acid decarboxylase from Pseudomonas putida (mdlC) and native
152 tyric acid synthesizing enzyme glutamic acid decarboxylase (GAD) and choline acetyltransferase (ChAT)
153 th region-specific changes in glutamate acid decarboxylase (GAD) and vesicular GABA transporter expre
154 The human neuroendocrine enzyme glutamate decarboxylase (GAD) catalyses the synthesis of the inhib
155 ed by enzymes derived from two glutamic acid decarboxylase (GAD) genes, GAD1 and GAD2, both of which
157 hosphate-diaphorase (NADPH-d), glutamic acid decarboxylase (GAD), cytochrome oxidase (CO), and calret
159 (GABA) transporter (vGAT) and glutamic acid decarboxylase (GAD)65 in the GABAergic contacts that the
161 , we study the distribution of glutamic acid decarboxylase (GAD)67 and GLY transporter 2 (T2) in axon
162 2; VGluT2) and GABA signaling (glutamic acid decarboxylase; GAD, and vesicular GABA transporter; VGaT
163 orters (vglut1, vglut2.1, vglut3), glutamate decarboxylases (gad1, gad2), and choline acetyltransfera
165 slet antigen (IA)-2, IA-2beta, and glutamate decarboxylase (GAD65) are major autoantigens in type 1 d
166 UT1) and the 65 kDa isoform of glutamic acid-decarboxylase (GAD65) as markers of, respectively, Ia af
167 beled for the 65 kD isoform of glutamic acid decarboxylase (GAD65), PV and the GABA(A) receptor alpha
168 nding reductions in this region of glutamate decarboxylase (GAD65/67) and markers of dendritic spines
169 oded 67-kDa protein isoform of glutamic acid decarboxylase (GAD67) is a hallmark of schizophrenia.
170 evels of the 67 kDa isoform of glutamic acid decarboxylase (GAD67) protein, the enzyme responsible fo
171 ssion of the 67-kDa isoform of glutamic acid decarboxylase (GAD67), a key enzyme for GABA synthesis,
172 vels of tyrosine hydroxylase (TH), glutamate decarboxylase (GAD67), and vesicular glutamate transport
173 tibody responses to insulin (IAA), glutamate decarboxylase (GADA), IA-2, IA-2beta, and ZnT8 were anal
176 photosynthesizing tissue is used for glycine decarboxylase (GDC), necessary for the high-flux photore
177 phosphate dikinase-independent (but glycine decarboxylase (GDC)-dependent) manner, and recuperates p
179 partate semialdehyde dehydrogenase, arginine decarboxylase gene activator, GTP cyclohydrolase I and a
180 omato plants over-expressing mouse ornithine decarboxylase gene under the control of fruit-specific p
181 es an upregulation of the insect's ornithine decarboxylase gene, which sequesters arginine for polyam
182 pression and activity of three tea glutamate decarboxylase genes (CsGAD1, 2, and 3), and their encode
184 hydroxymethyltransferase (SHMT2) and glycine decarboxylase (GLDC) are highly expressed in the pseudop
185 e, catalase, superoxide dismutase, ornithine decarboxylase, glutamate receptor, and ammonia transport
189 in one integrated device to detect histidine decarboxylase (HDC) gene directly from human white blood
190 carboxypeptidase A3 (CPA3), and L-histidine decarboxylase (HDC) gene expression; and serum markers (
191 ure termination codon in the human histidine decarboxylase (Hdc) gene has been identified in a family
197 the histamine-synthesizing enzyme histidine decarboxylase (HDC-KO) or acutely depleted of histamine
198 crystal structure of a Pseudomonas malonate decarboxylase hetero-tetramer, as well as biochemical an
200 antigens are established (insulin, glutamate decarboxylase, IA2, and zinc transporter-8), but the mol
201 legans, RNAi depletion of phosphatidylserine decarboxylase in dopaminergic neurons expressing alpha-s
202 tant cells, in which panD encoding aspartate decarboxylase in E. coli had been knocked out, thus conf
203 the GABA-synthesizing enzyme, glutamic acid decarboxylase in EC were confirmed by immunostaining and
204 c protein-immunocytochemistry, glutamic acid decarboxylase in situ hybridization, and parvalbumin-imm
205 n addition, we identified TbPSD as type I PS decarboxylase in the mitochondrion and found that it is
208 bunit of the photorespiratory enzyme glycine decarboxylase, increased accumulation of glycine and gly
209 amine analog and potent S-adenosylmethionine decarboxylase inhibitor, decreases HIV expression in mon
212 dual function enzyme, mevalonate 5-phosphate decarboxylase is unable to carry out the first phosphory
213 ne biosynthetic enzyme, S-adenosylmethionine decarboxylase, is regulated by heterodimer formation wit
214 romoter regulatory elements of glutamic acid decarboxylase isoforms (Gad1 and Gad2), which regulate G
215 also improved by overexpression of keto-acid decarboxylases (KDC) and alcohol dehydrogenase (ADH).
216 uring oral hygiene restriction (OHR), lysine decarboxylase (LDC) in dento-gingival biofilms converts
217 Pase RavA and the decameric inducible lysine decarboxylase LdcI-is reconstructed by cryo-electron mic
218 ng vagal activation of aromatic L-amino acid decarboxylase, leading to the production of dopamine in
220 the promoter of the gene encoding glutamate decarboxylase-like protein 1 (GADL1) in 94 patients who
221 identified the pyridoxal phosphate-dependent decarboxylase-like proteins in the translated proteome o
222 ntify a novel family within the acetoacetate decarboxylase-like superfamily with divergent active sit
225 SIRT4 deacetylates and inhibits malonyl CoA decarboxylase (MCD), an enzyme that produces acetyl CoA
226 cteria contain a biotin-independent malonate decarboxylase (MDC), which allows them to use malonate a
227 with a distinct prosthetic group, as well as decarboxylase (MdcD-MdcE) and acyl-carrier protein trans
229 zyme in this pathway, mevalonate diphosphate decarboxylase (MDD), acts on mevalonate diphosphate (MVA
230 form of Tourette syndrome due to L-histidine-decarboxylase mutation, with similar features in human a
232 olled by the rate-limiting enzymes ornithine decarboxylase (ODC) and spermidine-spermine N(1)-acetylt
233 ls (RWPE-1) with overexpression of ornithine decarboxylase (ODC) and used it for in vitro and in vivo
238 activity and protein abundance of ornithine decarboxylase (ODC), the committed enzyme for polyamine
239 we demonstrate that inhibition of ornithine decarboxylase (ODC), the rate-limiting enzyme in polyami
241 The plasma levels of arginase I, ornithine decarboxylase (ODC), transforming growth factor beta (TG
243 matic decarboxylation; however, oxaloacetate decarboxylases (ODx) were so far not identified in eukar
244 e deletion of the orotidine 5'-monophosphate decarboxylase (OMPDC) and uridine phosphorylase (UP) gen
245 for activation of orotidine 5'-monophosphate decarboxylase (OMPDC) by interactions of side chains fro
247 double mutant of orotidine 5'-monophosphate decarboxylase (OMPDC) from Saccharomyces cerevisiae that
248 to insulin, autoantibodies to glutamic acid decarboxylase or insulinoma-associated antigen 2, or dia
251 partate is a pyruvoyl-containing l-aspartate decarboxylase (PanD), the enzyme in M. jannaschii is a p
252 d, in microorganisms, the action of pyruvate decarboxylase (PDC) and pyruvate formate lyase (PFL)-enz
254 Microorganisms - CCDM 824 and CCDM 946) with decarboxylase positive activity in a model system of Dut
255 in the ganglion cell layer is glutamic acid decarboxylase-positive and shows the morphology of widef
256 control rats, there were fewer glutamic acid decarboxylase-positive neurons in the former cultures.
258 ay by an inhibitor of arginase and ornithine decarboxylase protected the mice from AD-like pathology
259 ine hydroxylase (TH) and aromatic amino acid decarboxylase, providing a novel mechanism for dopamine
260 double RNAi depletion of phosphatidylserine decarboxylase (psd-1) and choline/ETA phosphotransferase
261 , we demonstrate that the phosphatidylserine decarboxylase Psd1, located in the inner mitochondrial m
262 of a key pathway enzyme, phosphatidylserine decarboxylase Psd1, which generates phosphatidylethanola
265 This first-time study of the phenylacetate decarboxylase reaction constitutes an important step in
267 erase (ScTIM), yeast orotidine monophosphate decarboxylase (ScOMPDC), and human liver glycerol 3-phos
268 cultured MCs were transfected with histidine decarboxylase short hairpin RNA to decrease histamine se
269 nations thereof, deficient in 2-oxoglutarate decarboxylase (Sll1981), succinate semialdehyde dehydrog
272 obutyric acid pathway or alpha-ketoglutarate decarboxylase/succinic semialdehyde dehydrogenase) plays
273 positive to antibodies against glutamic acid decarboxylase, suggesting that they use gamma-aminobutyr
274 struction of the rhamnose-regulated arginine decarboxylase system allowed us to render S. Typhi acid
277 by inserting Shigella glutaminase-glutamate decarboxylase systems coexpressed with S. sonnei form I
278 ucei PS synthase 2 (TbPSS2) and T. brucei PS decarboxylase (TbPSD), two key enzymes involved in amino
279 zymes required for their synthesis, tyrosine decarboxylase (TDC) and tyramine beta-hydroxylase (TBH).
281 toacyl acyl-carrier protein, and ShMKS1 is a decarboxylase that converts the resulting 3-ketoacids to
282 bacteria have a biotin-independent malonate decarboxylase that is crucial for their utilization of m
283 al malic enzymes (ME2 and ME3) are oxidative decarboxylases that catalyse the conversion of malate to
284 revealed colocalization of DA, l-amino acid decarboxylase, the DA transporter, and vesicular monoami
285 ntibodies directed against the glutamic acid decarboxylase, the rate-limiting enzyme for the producti
287 g pathway regulates translation of ornithine decarboxylase, thereby enhancing polyamine biosynthesis
289 C supernatant fluids increased CCA histidine decarboxylase, vascular endothelial growth factor, and M
290 nerate mevalonate 3,5-bisphosphate and a new decarboxylase we describe here, mevalonate 3,5-bisphosph
291 pressing different isoforms of glutamic acid decarboxylase were found to have differential subregiona
292 y decreased by inhibition of the enzyme dopa decarboxylase, which converts (11)C-5-HTP to (11)C-serot
294 e levels of mitochondrial phosphatidylserine decarboxylase, which is involved in the synthesis of mit
295 ic acid (GABA)-synthesizing enzyme glutamate decarboxylase, which is present in inhibitory afferents
296 racterization of a branched-chain amino acid decarboxylase, which would appear to be responsible for
297 oplasm, providing the substrate for arginine decarboxylases, which consume a cellular proton ending u
298 me complex that have evolved into a pyruvate decarboxylase, while other copies retained the essential
299 we also determine the structure of malonate decarboxylase with CoA in the active site of MdcD-MdcE.
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