ライフサイエンスコーパス: decidual

1 The decidual abnormalities in the IL-15(-/-) mice however di

2 The loss of uNK cells results in decidual abnormalities, including thickening of the arte

3 Conversely, decidual accumulation of maternal T cells with fetal spe

4 lation allowed for target gene upregulation, decidual activation, and labor entry.

5 expressed in the epithelial cells, although decidual and embryonic cells also accumulate this mRNA.

6 n expression of NF-kappaB, TNF, and IL-10 in decidual and myometrial macrophages in C57BL/6J mice.

7 In this study we examined the decidual and peripheral CD8(+) T cell pool for CD45RA, C

8 lpha and IL-6) and chemokines (MIP-1beta) in decidual and placental cells.

9 ecidual tissue and cause a rapid increase in decidual and systemic TNF-alpha levels.

10 the relative contribution and importance of decidual and trophoblast ADA at the maternal-fetal inter

11 ein for IFN-gamma was detected in both total decidual and uNK cell fractions.

12 Total decidual and uNK cells from 8-10 wk and 12-14 wk gestati

13 ggest therefore that uDCs directly fine-tune decidual angiogenesis by providing two critical factors,

14 Depletion of uDCs altered decidual angiogenesis, suggesting that uDCs contribute t

15 Because decidual antigen-presenting cells (APCs) may be importan

16 nterstitial cytotrophoblasts, we observed in decidual areas containing interstitial cytotrophoblasts

17 ua express strong FasL immunoreactivity, and decidual areas containing interstitial cytotrophoblasts

18 Compared with decidual areas devoid of interstitial cytotrophoblasts,

19 acental development, and defects in maternal decidual arteries.

20 Decidual artery remodeling is essential for a healthy pr

21 a vital regulatory cascade involving IL-33, decidual B cells and PIBF1 in safeguarding term pregnanc

22 iated stromal cells, and massive breakage of decidual blood vessels, leading to uterine hemorrhage an

23 patterns in the uterine endometrium, at the decidual boundary, in the decidual vasculature, and in t

24 trual endometrium and the mouse uterus after decidual breakdown, evidence that VEGF has pleiotropic e

25 portant for iTreg cell induction, we studied decidual CD14(+) APCs using immunohistochemistry and flo

26 Human decidual CD14(+) macrophages and CD56(+) NK cells were i

27 We show that decidual CD14(+)DC-SIGN(+) APCs are closely associated w

28 These results suggest that decidual CD14(+)DC-SIGN(+) APCs may play important roles

29 Decidual iNKT cells comprised 0.48% of the decidual CD3+ T cell population, a frequency 10 times gr

30 hird trimester decidua and demonstrated that decidual CD4(+) and CD8(+) T cells exhibit a highly diff

31 usly produce IL-12, whereas freshly isolated decidual CD4(+) T cells expressed high levels of activat

32 Interestingly, decidual CD4+ iNKT cells exhibited a striking Th1-like b

33 Understanding how decidual CD8(+) T cell (CD8(+) dT) cytotoxicity is regul

34 Regulation of decidual CD8(+) T cell differentiation may play a crucia

35 Decidual CD8(+) T cells are the main candidates to recog

36 Our data demonstrate that decidual CD8(+) T cells mainly consist of differentiated

37 B mRNA in decidual EM T cells suggests that decidual CD8(+) T cells pursue alternative means of EM c

38 l sections were immunostained for FKBP51 and decidual cell (DC) and interstitial trophoblast (IT) mar

39 al regulator of the unique ECM that controls decidual cell architecture and differentiation, and it p

40 nized bacteria in the pregnant uterus led to decidual cell death, tissue disintegration, and resorpti

41 suggests that it acts locally and regulates decidual cell development and the endometrial vasculatur

42 L-6 levels in first trimester leukocyte-free decidual cell incubations, as measured by real time quan

43 HtrA1 and HtrA3 are crucial for trophoblast-decidual cell interaction in the control of trophoblast

44 s tightly regulated and involves trophoblast-decidual cell interaction.

45 Therefore, decidual cell-derived IL-6 may contribute to excess circ

46 ecidual hemorrhage, which form thrombin from decidual cell-expressed tissue factor.

47 oid receptor (GR), and total and p-ERK1/2 in decidual cells (DCs) and interstitial trophoblasts (IT)

48 ignificantly higher interleukin-6 HSCOREs in decidual cells (DCs) but not in interstitial trophoblast

49 their abilities to attach to and invade both decidual cells and lung epithelial cells.

50 iters, cytomegalovirus replicated in diverse decidual cells and placental trophoblasts and capillarie

51 extrinsic pathway of apoptosis among uterine decidual cells and spongiotrophoblasts.

52 Decidual cells are crucially involved in creating the in

53 Thus, secretion of gal1 by dNKs and other decidual cells contributes to the generation of an immun

54 Decidual cells differentiate from their precursors, the

55 In the mouse, decidual cells differentiate from uterine stromal cells

56 Here, we demonstrate that isolated decidual cells express sFlt-1 mRNA, suggesting that they

57 Also, decidual cells from patients with sPE, which dedifferent

58 her immunohistochemical staining for IL-6 in decidual cells from preeclamptic versus preterm, gestati

59 to morphologically and functionally distinct decidual cells in a unique process known as decidualizat

60 , addition of exogenous prolactin to primary decidual cells in culture also caused a marked decrease

61 human endometrial stromal cells (HESCs) into decidual cells in response to progesterone, although the

62 (IL-8) was evaluated in leukocyte-free term decidual cells incubated with estradiol (E2; control) or

63 In human first-trimester decidual cells incubated with estradiol, tumor necrosis

64 Decidual cells incubated with NK cell-derived IFN-gamma

65 chment, de novo synthesis of estrogen by the decidual cells is critical for stromal differentiation.

66 23 strains, however, attached to and invaded decidual cells less than both ST-17 strains.

67 y, thrombin-enhanced IL-8 expression in term decidual cells may explain how abruption-associated PPRO

68 clusively in luminal epithelial and adjacent decidual cells occurred at implantation sites of hamster

69 The authors' work thus implicates the decidual cells of the mother as the culprit responsible

70 ransiently induced at a high level in mature decidual cells of the uterine stroma.

71 ble induction of GPR64 expression in uterine decidual cells points to its potential physiological sig

72 We found thatFaah(-/-)decidual cells progressively underwent premature senesce

73 icipate in the formation and function of the decidual cells remain poorly understood.

74 Furthermore, we find that uterine decidual cells represent a cell-cell interaction hub wit

75 lantation; however, postimplantation uterine decidual cells showed terminal differentiation and senes

76 a 29-kDa protein and localizes to a band of decidual cells surrounding the trophoblast cell layer on

77 The decidual cells synthesize extracellular matrix (ECM) com

78 may provide important signals to maternal NK decidual cells that interact with trophoblast cells at t

79 e endometrial stromal cells into specialized decidual cells that support the development of the impla

80 nts expression of MMP-1, MMP-3, and MMP-9 in decidual cells to interfere with normal stepwise EVT inv

81 e/paracrine enhancer of sFlt-1 expression by decidual cells to promote pre-eclampsia by interfering w

82 C, IFN-gammaR1, and -R2 to vimentin-positive decidual cells versus cytokeratin-positive interstitial

83 e data, we hypothesize that TGF-beta acts on decidual cells via ALK5 to induce expression of other gr

84 Confluent decidual cells were primed for 7 days in either estradio

85 Finally, treatment of primary decidual cells with steroid hormones or 8-bromo-cAMP rev

86 yncytiotrophoblasts, chorionic trophoblasts, decidual cells, and amniotic epithelial cells, as well a

87 tromal cells surrounding the blastocyst into decidual cells, and protection of the "semiallogenic" em

88 Previous studies show that preeclamptic decidual cells, but not interstitial EVTs, display highe

89 ctions between the conceptus and surrounding decidual cells, but the involvement of clock genes in th

90 First trimester human decidua is composed of decidual cells, CD56(bright)CD16(-) decidual natural kil

91 e mice also revealed increased cell death in decidual cells, decreased cell proliferation in undiffer

92 es and differentiates into large epithelioid decidual cells, is critical to the establishment of feta

93 s associated with aberrations in mesometrial decidual cells, mesometrial vascular integrity, and disr

94 In contrast to first trimester decidual cells, thrombin did not affect sFlt-1 levels in

95 Moreover, in first trimester decidual cells, thrombin enhanced sFlt-1 mRNA levels, as

96 d in their abilities to attach to and invade decidual cells, whereas there were no differences with l

97 s, sFlt-1 expression has not been studied in decidual cells, which are the predominant cell type enco

98 induces differentiation of uterine stroma to decidual cells, which regulate embryo-uterine interactio

99 to morphologically and functionally distinct decidual cells, which support embryonic growth and survi

100 cells undergo terminal differentiation into decidual cells, which support the proper progression of

101 minin constituent of the ECM produced by the decidual cells.

102 production in cultured first-trimester human decidual cells.

103 id not affect sFlt-1 levels in cultured term decidual cells.

104 ctor-alpha affected sFlt-1 expression in the decidual cells.

105 s assessed in leukocyte-free first trimester decidual cells.

106 SA-beta-Gal) staining and gammaH2AX-positive decidual cells.

107 signaling and inhibited mTORC1 signaling in decidual cells.

108 This signature was also observed in human decidual cells.

109 R-1) was localized to amnion mesenchymal and decidual cells.

110 ile VEGF is upregulated in adjacent maternal decidual cells.

111 icit an endoplasmic stress response in human decidual cells.

112 against excessive VEGFA produced by maternal decidual cells.

113 A and protein expression was constitutive in decidual cells.

114 rate at which embryos and their surrounding decidual covering became infected, suggesting that intra

115 human glycodelin from first trimester human decidual cytosol by using a rapid two-step high-performa

116 Strikingly, decidual DCs remained immobile even after being stimulat

117 In this study, we tested the hypothesis that decidual defects are an important determinant of the pla

118 l functions necessary for propagating normal decidual development during the post-implantation period

119 To further analyze the role of the decidual ECM in modulating maternal-embryo interactions,

120 with peripheral blood EM CD8(+) T cells, the decidual EM CD8(+) T cells display a significantly reduc

121 ased perforin and granzyme B mRNA content in decidual EM CD8(+) T cells in comparison with peripheral

122 gh levels of perforin and granzyme B mRNA in decidual EM T cells suggests that decidual CD8(+) T cell

123 ttle is known regarding the second-trimester decidual environment.

124 Many decidual factors are likely to play a role in regulating

125 orally coincides with PR-A isoform-dependent decidual formation at the time of implantation.

126 oRNAs (miRNAs) involved in the regulation of decidual gene expression in human endometrial stromal ce

127 l proliferation with initiation of aperiodic decidual gene expression; uncoupling of these events may

128 ls of LIF-null animals showed no evidence of decidual giant cell formation even by day 6 of pregnancy

129 These immune cells, termed "decidual granulated leukocytes," are composed predominan

130 ntal development without apparent defects in decidual growth.

131 in placentas obtained after overt abruption (decidual hemorrhage) with or without PPROM and in contro

132 associated with maternal thrombophilias and decidual hemorrhage, which form thrombin from decidual c

133 infection induces placental inflammation and decidual hyperplasia as well as concomitant increase in

134 Maternal decidual IGFBP-1 excess is also associated with impaired

135 s hypothesis, we have studied the effects of decidual IGFBP-1 excess on fetoplacental growth in trans

136 Decidual IGFBP-1 overexpression has a marked effect on p

137 icate crosstalk between EVTs, SpA cells, and decidual immune cells that governs their recruitment to

138 xic decidual NK cells, and 2) the decline of decidual immunotolerant M2-like macrophages.

139 In the decidual implantation site, preeclampsia is accompanied

140 th intermediate to high neutralizing titers, decidual infection was suppressed and the placenta was s

141 Decidual iNKT cells comprised 0.48% of the decidual CD3+

142 fferential pattern of cytokine expression by decidual iNKT cells suggests that maternal iNKT cell int

143 ared to their peripheral blood counterparts, decidual iNKT clones were strongly polarized toward gran

144 confer sufficient stability at the placental-decidual interface.

145 ituent of the integrin receptors targeted by decidual laminins, also inhibited this differentiation p

146 mice is required for proper formation of the decidual layer and remodeling of the uterine vasculature

147 terus, and is essential for formation of the decidual layer of the placenta and remodeling of the ute

148 resulting in reduced spongiotrophoblast and decidual layers in the placenta.

149 ent stages and provide the first evidence of decidual leukocyte involvement in trophoblast-independen

150 mokines in the uterus and their receptors on decidual leukocytes allowed us to identify numerous rece

151 and the expression of chemokine receptors on decidual leukocytes by RNase protection.

152 multicolor flow cytometric analyses of human decidual leukocytes detected an elevation in tissue resi

153 immunoglobulin-like receptor B1 receptors on decidual leukocytes is compelling.

154 ; evidence from animal models indicates that decidual leukocytes play a role.

155 oblasts come in direct contact with maternal decidual leukocytes.

156 , the placenta triggers the development of a decidual lymphatic circulation, which we theorize plays

157 In summary, we demonstrated that decidual M1-like macrophages are associated with spontan

158 n M1-like macrophages in decidual tissue; 3) decidual M2-like macrophages are reduced in preterm preg

159 s an important class A scavenger receptor in decidual macrophage phagocytosis of this microbe.

160 this study, two distinct subsets of CD14(+) decidual macrophages (dMs) are found to be present in fi

161 CD14(+)CD163(+)CD206(+)CD209(+) phenotype of decidual macrophages and produced IL-10 and CCL18 but no

162 his observation was confirmed in situ, where decidual macrophages and T cells are continuously expose

163 f human macrophages, including placental and decidual macrophages and used a novel intrauterine infec

164 Decidual macrophages are implicated in the local inflamm

165 ies, regardless of the presence of labor; 4) decidual macrophages express high levels of TNF and IL-1

166 Rgamma) during spontaneous preterm labor; 5) decidual macrophages from women who underwent spontaneou

167 G reduces the expression of TNF and IL-12 in decidual macrophages from women who underwent spontaneou

168 d IL-6 levels may contribute to an excess of decidual macrophages implicated in shallow extravillous

169 In vitro phagocytosis assays with human decidual macrophages incubated with pharmacological inhi

170 to determine the mechanisms whereby uterine decidual macrophages phagocytose this bacterium and test

171 We hypothesized that decidual macrophages undergo a proinflammatory (M1) pola

172 In this study, we show that: 1) decidual macrophages undergo an M1-like polarization dur

173 cterium and tested the hypothesis that human decidual macrophages use class A scavenger receptors to

174 The amount of these cytokines secreted by decidual macrophages was substantially greater than that

175 retion of M1- and M2-associated cytokines in decidual macrophages, and of proinflammatory cytokines (

176 culture supernatants of human placental and decidual macrophages, identifying them as a major source

177 L14 induced chemotaxis of both dNK cells and decidual macrophages, whereas CXCL6 also induced dNK cel

178 but also induces expression of prolactin, a decidual marker gene, in progestin-treated HESCs without

179 erexpression inhibits the induction of major decidual marker genes, including IGFBP1, WNT4 and PRL.

180 zation by regulating the expression of major decidual marker genes.

181 urther showed that Hoxa10 and cyclin D3, two decidual markers, control transcriptional regulation and

182 embrane and laminin 10/11 in the surrounding decidual matrix, suggest that these laminin isoforms inf

183 ion of cytolytic molecules suggests that the decidual microenvironment reduces CD8(+) dT effector res

184 chorioamnionitis could be pivotal in skewing decidual monocyte differentiation to macrophages.

185 Decidual natural killer (dNK) cells play a role in SA re

186 posed of decidual cells, CD56(bright)CD16(-) decidual natural killer (dNK) cells, and macrophages.

187 In contrast, decidual natural killer cell-derived IFN-gamma reverses

188 The interaction of noncytotoxic decidual natural killer cells (dNK) and extravillous tro

189 eceptor 2DS1 (KIR2DS1) expressed by maternal decidual natural killer cells (dNK) and the presence of

190 Cocultures of HLA-G+ EVT with sample matched decidual natural killer cells (dNK), macrophages, and CD

191 tal trophoblasts encounter abundant maternal decidual natural killer cells (dNK).

192 educed fusobacterial-induced fetal death and decidual necrosis without affecting the bacterial coloni

193 uption-associated PPROM, we examined whether decidual neutrophil infiltration complicates abruption-a

194 Collectively, these data show that decidual neutrophil infiltration is not essential for th

195 Abruptions were associated with a marked decidual neutrophil infiltration that peaked after PPROM

196 lain how abruption-associated PPROM promotes decidual neutrophil infiltration.

197 sulted in a 7-fold increase in the number of decidual neutrophils compared with control mice receivin

198 ith peripheral blood neutrophils (PMNs), the decidual neutrophils expressed high levels of neutrophil

199 Uterine decidual NK (dNK) cells and macrophages infiltrate the S

200 In contrast to peripheral blood NK cells, decidual NK (dNK) cells lack cytotoxicity, secrete proan

201 Here, CD56(bright) uterine decidual NK (dNK) cells were compared with the CD56(brig

202 Retrospective analysis of the decidual NK cell transcriptome revealed a strong senesce

203 e receptor (KIR) genes expressed by maternal decidual NK cells (dNK) and HLA-C genes expressed by fet

204 on site of the fetal-maternal interface, and decidual NK cells have been demonstrated to facilitate e

205 immunoglobulin receptors (KIRs) on maternal decidual NK cells is a key factor in the development of

206 hich involves 1) the activation of cytotoxic decidual NK cells, and 2) the decline of decidual immuno

207 substantially greater than that secreted by decidual NK cells.

208 nsition to CD16(-)CD9(+) NK cells resembling decidual NK cells.

209 es that elicit recruitment and activation of decidual NK cells.

210 L. monocytogenes infection in primary human decidual organ cultures and in the murine decidua in viv

211 TLA-2beta mRNA precisely overlapped with the decidual phase of pregnancy.

212 nisms that underlie differentiation into the decidual phenotype remain largely undefined.

213 d)) confirmed a Notch1-dependent hypomorphic decidual phenotype.

214 ncy was often complicated by bleeding at the decidual-placental interface and fetal growth retardatio

215 Decidual PLP-J migrates as a 29-kDa protein and localize

216 ular changes that precede complete P-induced decidual progression.

217 MER39--contribute the enhancer/promoter for decidual prolactin (dPRL), which is dramatically induced

218 o-cAMP revealed a differential regulation of decidual prolactin expression from that of pituitary sug

219 ituitary prolactin appeared to down-regulate decidual prolactin levels.

220 ry prolactin secretion led to a rise in both decidual prolactin mRNA and protein expression.

221 in culture also caused a marked decrease in decidual prolactin mRNA expression.

222 okines related to prolactin (PRL), including decidual prolactin-related protein (DPRP).

223 ntation failure was associated with impaired decidual proliferation and differentiation.

224 terine stroma is incapable of undergoing the decidual reaction to support further embryonic developme

225 f the uterus to undergo a hormonally induced decidual reaction was lost.

226 ergo a well-characterized hormonally induced decidual reaction.

227 es resulted in stunted embryos and a reduced decidual reaction.

228 trophoblastic vesicles, which in turn induce decidual reactions.

229 down-regulation near embryos and attenuates decidual reactions.

230 Hysteroscopic assessment indicated a uniform decidual response (confirmed histologically in 40 of 41

231 Surprisingly, the decidual response is estrogen independent in the ERKO, a

232 x) mouse uterus resulted in the absence of a decidual response, confirming that uterine SRC-2 and -1

233 ombinant human BMP2 can partially rescue the decidual response, suggesting that the observed phenotyp

234 tation and inhibits P(4)-regulated genes and decidual response.

235 l as other unknown factor(s) associated with decidual response.

236 induced to undergo a progesterone-dependent decidual response.

237 NA knockdown leads to a grossly disorganized decidual response.

238 Gestational age-matched decidual sections were immunostained for FKBP51 and deci

239 l arteries remains largely restricted to the decidual segment.

240 nabinoid signaling is critical in regulating decidual senescence and parturition timing.

241 man preterm birth, we show here that uterine decidual senescence early in pregnancy via heightened ma

242 ies provide evidence that premature maternal decidual senescence resulting from heightened mTORC1 sig

243 in 53 (p53d/d mice), which exhibit premature decidual senescence that triggers spontaneous and inflam

244 ype mice at midgestation triggered premature decidual senescence utilizing CB1, since administration

245 Decidual senescence with heightened mTORC1 signaling is

246 f spontaneous preterm birth due to premature decidual senescence with increased mTORC1 activity and C

247 Moreover, a similar signature of decidual senescence with increased mTORC1 and COX2 signa

248 vances relevant to intra-amniotic infection, decidual senescence, and breakdown of maternal-fetal tol

249 ntifies a previously unidentified pathway in decidual senescence, which is independent of mTORC1 sign

250 duae, and inhibition of p38 halted premature decidual senescence.

251 at elevated expression of the T235 allele in decidual spiral arteries may cause first trimester ather

252 Decidual spiral arteriole (SpA) remodeling is essential

253 A concomitant artificial decidual stimulation was necessary to trigger this expre

254 sed to human cytomegalovirus (HCMV)-infected decidual stromal cells (DSC), particularly when DSCs exp

255 a and demonstrated that TAP2 is expressed by decidual stromal cells at the maternal-fetal interface.

256 ri-methyl histone H3 lysine 27 (H3K27me3) in decidual stromal cells dictate both elements of pregnanc

257 blood NK cells with conditioned medium from decidual stromal cells mirrored the effects of TGFbeta1.

258 lls when cultured in conditioned medium from decidual stromal cells supplemented with IL-15 and stem

259 l-attracting inflammatory chemokine genes in decidual stromal cells, as evidenced by promoter accrual

260 Decidual stromal cells, when isolated and cultured in vi

261 NK to human cytomegalo virus (HCMV)-infected decidual stromal cells.

262 Examination of embryos dissected from decidual swellings and in vitro culturing of blastocysts

263 Decidual T (dT) cells but not peripheral T (pT) cells bo

264 ced by trophoblasts potentially controls the decidual T cell cytokine profile.

265 in part, via its interaction with ILT2, for decidual T cell IL-4 production, known to be crucial for

266 Moreover, decidual T cells proliferated in response to fetal tissu

267 Transcriptional analysis of decidual T cells revealed a unique gene profile characte

268 Furthermore, within the same uterus the decidual tissue adjacent to mutant placentas displays ma

269 ow that aPL Abs are specifically targeted to decidual tissue and cause a rapid increase in decidual a

270 the anti-Listeria responses in the maternal decidual tissue are dependent on CSF-1-regulated macroph

271 Decidual tissue development requires a highly regulated

272 t heterozygote females expressed EGFP within decidual tissue in locations identical to endogenous Dpr

273 ttractants and to recruit neutrophils to the decidual tissue in response to Listeria infection.

274 y reduced neovascularization compared to the decidual tissue next to wild-type placentas.

275 successful implantation via their effects on decidual tissue remodeling, including angiogenesis, and

276 ich was confirmed by immunohistochemistry of decidual tissue sections.

277 steroid biosynthetic enzymes present in the decidual tissue to support de novo synthesis of E.

278 ) are found to be present in first-trimester decidual tissue, CD11c(HI) and CD11c(LO).

279 cells have been shown to be concentrated in decidual tissue, where they are able to suppress fetus-s

280 ctors that promote neovascularization in the decidual tissue.

281 ular epithelial cells of the first trimester decidual tissue.

282 stem/progenitor cells could be isolated from decidual tissue.

283 number of implantation sites with diminished decidual tissue.

284 n to uterine mesometrial and antimesometrial decidual tissue.

285 d on endothelial cells (ECs) of newly formed decidual tissue.

286 re more abundant than M1-like macrophages in decidual tissue; 3) decidual M2-like macrophages are red

287 ration of activated iNKT-like cells in human decidual tissues is associated with noninfection-related

288 After days E12 and E13, as decidual tissues regressed, D3 expression became localiz

289 lement induced by aPL antibodies targeted to decidual tissues, rather than by their anticoagulant eff

290 ulation of Fabp4 and Fatp4 in myometrial and decidual tissues, respectively; this suppression was res

291 mature dendritic cells to myometrial and/or decidual tissues.

292 ession levels than minor allele homozygotes; decidual trophoblasts showed strong CXCR3 immunoreactivi

293 Although increasing evidence supports that decidual (uterine) macrophages and regulatory T cells (T

294 Collectively, these studies identified the decidual uterus as a novel site of E biosynthesis and un

295 during early stages of pregnancy, promoting decidual vascular expansion through VEGF receptor 2 sign

296 ndometrium, at the decidual boundary, in the decidual vasculature, and in the myometrium during pregn

297 athology in SLE patients is characterized by decidual vasculopathy and infarction, and in APLS patien

298 of placental abruption, infarction, hypoxia, decidual vasculopathy, or thrombosis of fetal vessels (n

299 Later (d11.5), all decidual vessels express high levels of IGFBP-3 and lowe

300 re expressed in stromal cells of the primary decidual zone (PDZ).

301 n, at the mesometrial triangle and secondary decidual zone (SDZ) locations, is critical for successfu