ライフサイエンスコーパス: decline

1 site mortality, hospitalization, and 10% FVC decline.

2 upplements did not reduce risk for cognitive decline.

3 to neurodegenerative processes and cognitive decline.

4 ociates with immune activation and cognitive decline.

5 ve children (10 eyes), showing an average 1% decline.

6 mangrove forests, all of which are in global decline.

7 ween the Jacobian determinant, MAL, and FEV1 decline.

8 mporal distribution of points of physiologic decline.

9 D, incident CKD or mortality, and rapid eGFR decline.

10 eported consumption of taxed beverages would decline.

11 ment, there remain many questions about this decline.

12 MAL2) was significantly associated with FEV1 decline.

13 mixing may have acted to amplify the recent decline.

14 nts were not associated with additional FEV1 decline.

15 ed for growth may contribute to regeneration decline.

16 bute to mitigating the drivers of pollinator decline.

17 ing-related molecular changes and functional decline.

18 gocytosis and the stabilization of cognitive decline.

19 based occupational therapy delays functional decline.

20 mentia; global and domain-specific cognitive decline.

21 hms as the number of recorded neural signals decline.

22 0s coincided with steep kittiwake population decline.

23 llers from those who experience CD4(+)T-cell decline.

24 n inner membrane architecture and functional decline.

25 and secondarily for postoperative cognitive decline.

26 time resistance increased, and subsequently declined.

27 up while control arm patients' self-efficacy declined.

28 who consented to the parent study and 41 who declined.

29 pied by a species contracts as its abundance declines.

30 dividuals with CKD seems to diminish as eGFR declines.

31 cant decline in VA at 1 year (mean logMAR VA decline: 0.03 units, 95% CI, 0.008-0.05, P < 0.01).

32 in vs 50 placebo) had experienced an airflow decline; 138 patients (30%) died (78 azithromycin vs 60

33 25% were cognitively stable, 41% cognitively declined, 15% improved and 19% fluctuated over 36 months

34 ted trend, with a slight increase and modest decline (22.2%) in VCF placement rates over time; howeve

35 n-hospital mortality using clinical criteria declined (-3.3%/y [95% CI, -5.6% to -1.0%], P = .004), b

36 vely intact and has a low rate of vegetation decline; (3) land-based actions are optimal when the rat

37 d 73-88% by 2050 across warming scenarios, a decline 46-76% greater than estimated by global assessme

38 djusted rehospitalization/mortality risks to decline 50% from maximum values after discharge, (2) tim

39 among Bedouin and Jewish children aged <12m declined 74% (55-85%) and 43% (4-68%), respectively.

40 ales (ounces/transaction) in Berkeley stores declined 9.6% (p < 0.001) compared to estimates if the t

41 rate (R2) that was associated with cognitive decline after controlling for common neuropathologic con

42 b initially increased significantly and then declined after 2014 (0.1 in 2009 to 4.0 in 2015).

43 The IPD-related mortality rate declined after 7-valent PCV introduction from 1.25/10000

44 in the IG during the first year and smaller decline afterward.

45 rt failure may contribute to early cognitive decline and (vascular) dementia.

46 to 18%) had 1 or more episodes of functional decline and 28% (CI, 26% to 30%) recovered from their in

47 ment-fixing antibodies to merozoites did not decline and antibodies to IE surface antigens expressing

48 LPAR antagonist BMS002 protects against GFR decline and attenuates development of DN through multipl

49 were associated with increased hazard of CD4 decline and death.

50 y may accelerate the trajectory of cognitive decline and dementia.

51 prioritised if the rates of marine ecosystem decline and expansion are similar and low; (2) marine pr

52 ion that range from recovery to catastrophic decline and extirpation.

53 different locations to counter the trend of decline and its associated drivers.

54 Both flux decline and membrane scale formation decreased after a c

55 sis, AD+P subjects have more rapid cognitive decline and poor outcomes.

56 e viremia were the best predictors for viral decline and subsequent clearance.

57 e is causally associated with the functional decline and transformation of stem cells that characteri

58 Over the past several decades, BP has declined and hypertension control has improved.

59 sociated with concurrent and subsequent LVEF declines and recovery across therapies.

60 nsequence, stratospheric chlorine levels are declining and ozone is projected to return to levels obs

61 arker) with cognitive performance, cognitive decline, and dementia (N dementia/total = 195/7,499).

62 ically with amyloidosis to produce cognitive decline, and drives amyloid-independent brain atrophy du

63 less favourable populations are expected to decline, and in favourable climates they are expected to

64 in 2015; (2) sales of taxed beverages would decline, and sales of untaxed beverages would rise, in B

65 ct of drought and insect outbreaks on growth decline, and simultaneously partition and quantify their

66 l understanding of the drivers of population declines, and fundamentally different management actions

67 rbonaceous particle concentrations have been declining appreciably since 2010/11 due to the use of di

68 d species the rate and drivers of population decline are difficult to assess accurately: species' sur

69 Considering any ALP decline as a response, no patient with increasing ALP sh

70 ld-type mice, when circulating levels of OCN decline as they do with age.

71 d psychiatric disorders, including cognitive decline associated with Alzheimer's disease or schizophr

72 ndividuals potentially at risk for cognitive decline associated with preclinical AD.SIGNIFICANCE STAT

73 eGFR<60 ml/min per 1.73 m(2) and >/=30% eGFR decline at the third visit (2009-2013) relative to basel

74 poleward edge of a species distribution and declines at the range edge in the opposite or equatorial

75 0, we find that the average POLYEDU has been declining at a rate of approximately 0.010 standard unit

76 a species usually diminish as its abundance declines, because harvest costs increase.

77 h weight and decreased cognitive ability has declined between the 1950s and 1970s birth cohorts and t

78 Global richness is declining, but it is unclear whether sub-global trends d

79 tched comparison group, the mean total costs declined by $781.29 more per quarter per navigated patie

80 We found that global burned area declined by 24.3 +/- 8.8% over the past 18 years.

81 found that glucose-induced insulin secretion declined by 50% in rats housed at 5 degrees C for 28 h,

82 ulting binding potentials of the radioligand declined by 50-60% in the presence of unlabeled ligand.

83 The incidence of suspected meningitis cases declined by 57% (95% CI 55-59) in vaccinated compared wi

84 ased by 4% (-1 to 8), but hospitalised cases declined by 8% (3-13).

85 f, and the estimated number of excess deaths declined by about a third.

86 th increases in early years until 1999, then declines by 26% to 2015.

87 d much of the Kok effect can be explained by declining chloroplastic CO2 concentration (cc ) at low P

88 many neurological diseases characterized by declined cognitive flexibility.SIGNIFICANCE STATEMENT Ac

89 gnificantly after the tear, but continued to decline compared with control eyes at all end points.

90 HCT recipients showed significant cognitive decline compared with healthy controls.

91 of age-related gut pathology and functional decline, dampened protein synthesis and increased tolera

92 As mice age and NAD(+) concentrations decline, DBC1 is increasingly bound to PARP1, causing DN

93 shows progressive neurological and metabolic decline, decreased complex III activity, and increased p

94 ecline than clinically diagnosed cases (mean decline difference 2231 pg/dl, 95% CI: 897-3566, p = 0.0

95 Taken together, along with declines documented by others in field surveys, these re

96 engraftment, 3 of these patients experienced declining donor myeloid chimerism (DMC) levels with even

97 f cells to maintain proteostasis undergoes a decline during aging, rendering the organism susceptible

98 small number of recall lineages that did not decline during vaccine response and contained hypermutat

99 , reached a plateau during 2001 to 2008, and declined during 2008 to 2012 (annual percentage change,

100 ealthy individuals, renal function gradually declines during aging.

101 decisions balances the rate of biodiversity decline (e.g., the relaxation of extinction debts, or th

102 dicate that changes in foraging ecology, not declining environmental concentrations of mercury, are d

103 Postpartum hepatitis C viral (HCV) load decline followed by spontaneous clearance has been previ

104 aged >/=19 y who consume >/=2300 mg/d would decline from 88% (95% CI: 86%, 91%) to 71% (95% CI: 68%,

105 Panretinal photocoagulation treatments declined from 109 840 procedures in 2004 to 81 005 proce

106 The annual rates of infection by S. aureus declined from 2003 to 2014 by 4.2% (2.7% to 5.6%), attri

107 (NHANES); mean concentrations of most PFASs declined from 2007 to 2010 in Project Viva and NHANES.

108 for trend <0.001), while mortality for males declined from 48.6% in 2002 to 32.2% in 2014 (P for tren

109 In the Africa Region, the rotavirus AF declined from 54.8% (95% CI, 48.3%-61.5%) in rotavirus v

110 In-hospital mortality for females declined from 61.0% in 2002 to 49.0% in 2014 (P for tren

111 uctions in reef growth potential, which have declined from an average 4.2 to -0.4 mm yr(-1).

112 ues is linked to age-associated diseases and declining function, prompting efforts to eliminate them.

113 eline cognitive status (subjective cognitive decline: hazard ratio [HR] = 0.57, p < 0.05; mild cognit

114 The use of hamsters has declined, however, most likely due to the dearth of gene

115 may be a mechanism leading to lung function decline in a subset of children with asthma.

116 lmark of the ageing process is a significant decline in adaptive homeostasis capacity.

117 ast to previous reports, we did not detect a decline in all-cause pneumonia in older adults in any co

118 -beta-induced loss of synapses and cognitive decline in Alzheimer's disease mice.

119 s not represent a single response to a rapid decline in atmospheric pCO2 at the EOT.

120 The decline in both progression and relapse of EAE occurred

121 Decline in both telomere length and physical fitness ove

122 INTERPRETATION: Decline in cognitive function was more frequent with WBR

123 s, including cardiovascular disease, cancer, decline in cognitive function, and mortality.We investig

124 c females, production of Amh and Sox9, and a decline in Cyp19a1 and Foxl2.

125 were associated with reduced risks of >/=30% decline in eGFR (hazard ratio [HR]: 0.77; 95% confidence

126 ut HF, and 22% of patients with HF had rapid decline in eGFR compared with 8.5% in patients without H

127 iscussion was not associated with a temporal decline in either measure.

128 For men, 9.5% is the result of a decline in external injuries.

129 esia, reduced ovulation rate, and a dramatic decline in fertility is observed in alpha-SNAP-mutant fe

130 A concentration of histamine inducing a 20% decline in FEV1 (PC20 ) </=16 mg/mL showed a sensitivity

131 The mean (SD) rate of decline in FEV1 was 39.0 (58.6) ml/yr.

132 nts showed increase from baseline in PTH and decline in FGF23 by study week 4, with no differences in

133 ongly, with an early spring peak followed by decline in forests, and a more extended summer season in

134 After adjusting for inflation, the decline in funding to dental institutions from the NIDCR

135 LPAR inhibition also prevented the decline in GFR observed in vehicle-treated mice, such th

136 h as tectonics, sea-level fall and long-term decline in greenhouse gas concentrations during the late

137 .72, -1.37) and 2.77% (95% CI, -4.36, -1.77) decline in HOMA-IR and insulin respectively, and a 2.55%

138 cases were more likely to have a measurable decline in IP-10 at day 7 than clinically diagnosed case

139 ns in circulating GDF-15 are associated with decline in kidney function.

140 ter AKI may lead to progressive fibrosis and decline in kidney function.

141 onfidence interval, 1.09-2.07), but not with decline in left ventricular ejection fraction.

142 to the controller animals led to a specific decline in levels of CD8(+) T cells and the rapid reappe

143 AD reduces brain atrophy, prevents cognitive decline in LMCI and delays conversion to AD dementia for

144 nical symptoms and may result in a sustained decline in lung function.

145 iddle East (14%), and central Asia (16%) and decline in many African savannas (e.g., -18% in sub-Saha

146 To mitigate the decline in measles virus antibody titers in IVIGs and to

147 the first half of the 20th century, then the decline in mortality from coronary heart disease and str

148 frequency of cerebellar Purkinje cells and a decline in motor function.

149 2% (2.7% to 5.6%), attributable to an annual decline in MRSA of 10.9% (9.3% to 12.6%).

150 in a mouse model of replicative senescence, decline in muscle satellite cell-mediated regeneration c

151 AKT1-silenced plants exhibited a significant decline in net uptake of K(+) and Na(+) , resulting in d

152 fuel availability as evidenced by the rapid decline in neuronal function during ischemic attacks and

153 , moderately lowered IIS rescues age-related decline in neurotransmission through the Drosophila gian

154 everely affected countries despite the sharp decline in new cases in recent years.

155 Because functional decline in older adults has similar features, current in

156 nment, which was associated with significant decline in oocyte cleavage and blastocyst development af

157 tion, a process contributing to fibrosis and decline in organ function.

158 tes, we show that at least two-thirds of the decline in organic aerosol can be explained by changes i

159 sian spatial regression) to test whether the decline in pneumonia hospitalizations associated with va

160 important ecosystem function and the global decline in pollinators attenuates the resistance of natu

161 the cultivated lineage experienced a steady decline in population size (Ne ) thereafter.

162 s study provides strong evidence that if the decline in primary production continues, knock-on effect

163 le our elders showed the previously reported decline in rationality compared with younger subjects, c

164 The magnitude of decline in renal function that should be tolerated durin

165 but it is unclear whether this represents a decline in S. aureus infections overall.

166 ARA), was partially oxidized, resulting in a decline in saturates and aromatics, but increases in res

167 re likely to report a clinically significant decline in self-reported cognitive function than were co

168 NO2 and PM2.5 were associated with a faster decline in SI and a lower SI at age 18 years, independen

169 e reduction in mucosal damage occurs through decline in stem/clonogenic epithelial cell loss mediated

170 PrEP coverage could result in a significant decline in STI incidence among MSM.

171 Even with the large decline in TFA concentrations, differences between demog

172 a remote coral reef ecosystem, we observe a decline in the (15)N/(14)N of coral skeleton-bound organ

173 o laser axotomy model, we show a progressive decline in the ability of cut CNS axons to form a new gr

174 Here we show that a decline in the autophagy-lysosome system contributes to

175 The precipitous decline in the host's clinical status and the lack of ta

176 es initiated under STEP led to a decade-long decline in the incidence levels.

177 bjective was to determine whether there is a decline in the prevalence of AD in population-based coho

178 Due to a very slow decline in the prevalence of stunting, the total number

179 We observed a similar 59% decline in the risk of a district reaching the epidemic

180 zed in niches in the subependymal area and a decline in their number was observed with age.

181 of the altered glucose metabolism and memory decline in these disorders.

182 a primary contributor to TDF-associated BMD decline in this age group.

183 tuberculosis transmission and accelerate the decline in tuberculosis incidence and mortality.

184 se who were not treated showed a significant decline in VA at 1 year (mean logMAR VA decline: 0.03 un

185 onential growth results in a more pronounced decline in VieA specific activity compared to the classi

186 has stagnated among poor Americans and even declined in some demographic groups.

187 Under-5 mortality has declined in sub-Saharan Africa over the last decades.

188 n primary prevention, the rate of MI has not declined in young adults.

189 At each site, declines in accretion rates and parrotfish abundance wer

190 While the utility of NFL declines in advanced glaucoma, GCC remains a sensitive p

191 world's forests and contribute to worldwide declines in biodiversity and ecosystem functions.

192 This change was concurrent with declines in body condition of polar bears and observed c

193 esterol levels, and respond rapidly to small declines in cellular cholesterol by activating SREBPs, i

194 Median of the maximum declines in HIV-1 RNA were similar for the 40-120 mg onc

195 To determine whether the acute declines in kidney function in the intensive BP lowering

196 Despite important ART-related declines in KS incidence, men and women in South Africa

197 Severe drought caused major declines in leaf water potential, elevated foliar ABA co

198 In summary, although modest declines in neurocognitive performance were seen in sing

199 Plant mortality rates and biomass declines in response to drought depend on stomatal and x

200 pe characterized by time- and dose-dependent declines in rod and cone photoreceptor functions as earl

201 When left unchecked, algae can cause declines in seagrass productivity and persistence throug

202 Two donors exceeded 10-point declines in SF-36 summary scores and increased their HAD

203 Moreover, declines in silicon occurred mainly in native species (-

204 Significant declines in SSB sales, even in this relatively affluent

205 d CO2 and temperature will lead to long-term declines in the amount of carbon stored in agricultural

206 ination and development have led to dramatic declines in the global burden of measles, but the virus

207 ntrations of mercury, are driving short-term declines in THg concentrations in southern Beaufort Sea

208 ibotypes and was associated with substantial declines in total C difficile infections in northeast Sc

209 metamorphosis on insect chemistry were large declines in zinc concentrations coupled with increased d

210 ient cycling and climate regulation, but are declining in the face of multiple threats.

211 utcome model, risk-adjusted adverse outcomes declined, including mortality (3.57% to 2.15%), bleeding

212 D) is characterized by progressive cognitive decline, increasingly attributed to neuronal dysfunction

213 ubsequent disease progression and drives CD4 decline independently of the viral load.

214 d intention to treat, excluding patients who declined intervention or were withdrawn for protocol vio

215 Much of this decline is attributable to mass coral bleaching events a

216 een no formal evaluation of how much of this decline is attributable to the scale-up of antiretrovira

217 n the ratio of marine ecosystem expansion to decline is greater than 1:1.4, with terrestrial restorat

218 e precedence if the rate of marine ecosystem decline is high or if the adjacent catchment is relative

219 relatively intact but the rate of vegetation decline is high.

220 uch populations demonstrates that range-edge decline is not ubiquitous and is likely to be driven by

221 and the molecular signaling underlying their decline is obscure.

222 out airflow obstruction affect lung function decline is unknown.

223 However, predicting these declines is challenging in heterogeneous fragmented land

224 lty of females finding mates as male density declines is the most frequently reported mechanism of Al

225 r life, contributing to cognitive and memory decline, is unknown.

226 calories, specifically fat and sucrose, and declining levels of daily physical activity.

227 onies initiated by an aged haploid cell show declined mating probability at an early stage and recove

228 In fact, there is evidence that the rate of decline may have abated and may even be showing early si

229 lture and property.Against the backdrop of a declining monsoon, the number of extreme rain events is

230 n altered basal ganglia neurodevelopment and declined motor performance in high Mn exposed children.

231 Longitudinal associations between functional decline, muscle strength and survival with plasma creati

232 Mild cognitive decline occurred in half.

233 Thus, climate change has led to a decline of 1/3 in the capacity of these disturbed fores

234 lear evidence of a marked pre-bloom silicate decline of 1.5-2 microM throughout the winter mixed laye

235 esistance in the membranes, whose flux had a decline of 8% after 24 h of operation in biofouling expe

236 that of the control membranes had a greater decline of approximately 21%.

237 Most striking was the decline of binding stoichiometry with linking number.

238 t and severity of anaphylaxis as measured by decline of body temperature, behavioral effects, serum I

239 Using diverse case studies, including the decline of coral reefs, coastal defences from flooding,

240 revious studies have tended to attribute the decline of Kleaf to embolism in the leaf vein xylem.

241 rom determinations in vitro, we discovered a decline of noradrenergic projections in vivo in brain of

242 tical mitochondrial quantity causes a severe decline of replicative life span of daughter cells.

243 77 78 References 78 Recent decades have seen declines of entire plant clades while other clades persi

244 Addressing population declines of migratory insects requires linking populatio

245 hat serum concentrations of nearly all PFASs declined on average 10% to 20% per year.

246 are multiple stressors implicated in colony declines, one stressor being the exposure to pesticides.

247 In both groups, ADCS ADL scores declined over 24 months.

248 f sleep, while memory for both feature types declined over a day awake.

249 PM2.5 precursor emissions have declined over the course of several decades, following t

250 n-resistant Staphylococcus aureus (MRSA) has declined over the past decade, but it is unclear whether

251 gests that added-sugars and SSB intakes have declined over the same time frame.We investigated recent

252 Adjusted mortality rates slightly declined over the study period.

253 approximately 3% of Cr(III) deposited) that declined over time.

254 s (except weight-for-length), accompanied by declines over time in seasonal variability.

255 Marginal populations declined overall during the past two decades; however, t

256 ion between lesion volume and neurocognitive decline (p = 0.0022).

257 across cohorts, including a slightly faster decline (p = 0.021) on the MMSE for Asians (-0.20 SD/dec

258 ays of arginine deprivation, mTORC1 activity declined paralleling a selective down-regulation of SREB

259 One individual declined participation after randomisation and two patie

260 .77, P < .001), for an estimated $19 million decline per year across the network.

261 a biphasic force decay with an initial slow decline (phase 1) and a subsequent 3-5-fold faster major

262 exhibit symptoms within 3-5 years of age and declining physical functions before attaining puberty.

263 not ubiquitous and is likely to be driven by declining population density at the landscape scale rath

264 ion of spherical and toroid genomes revealed declining radii of gyration for neutrophil chromosomes.

265 reveal that neuronal function and integrity decline rapidly with age, culminating in activity-depend

266 aintained until shortly before diagnosis and declines rapidly at the time of clinical onset of diseas

267 lism were predictive of subsequent cognitive decline rated with the MMSE and MoCA.

268 ent within deer habitat were correlated with declining recruitment rates, particularly within seasona

269 ntal institutions, it is unclear if this net decline reflects a long-term trend.

270 ive dysfunction and other forms of cognitive decline related to immune-to-brain communication, such a

271 participation buffered the risk of cognitive decline resulting from housing damage.

272 creasing age, stem cell functional abilities decline, resulting in reduced organ function and delays

273 risk of SCC after organ transplantation has declined significantly since the mid-1980s in Norway.

274 Bumblebees in Europe have been in steady decline since the 1900s.

275 After steady decline since the 1990s, tuberculosis (TB) incidence in

276 Risk-adjusted in-hospital mortality declined slightly in the overall cohort from 9.3% to 8.9

277 elderly patients with newly diagnosed cancer declined substantially after the ACA, especially among l

278 Rates of sudden death declined substantially over time among ambulatory patien

279 ve high IP-10 levels at D0 and had a steeper decline than clinically diagnosed cases (mean decline di

280 reduction in GFR, followed by an age-related decline that may be more rapid in related donors.

281 creased risk of adverse events and cognitive decline, there is an unmet need for well-tolerated and e

282 aths peaked at 231,000 per annum in 2006 and declined to 95,000 in 2014, a reduction of 74.7% (95% CI

283 Center who were eligible for this trial but declined to participate or had no financial coverage for

284 Patients were excluded if they declined to participate, could not read or write in Engl

285 Our findings link these declines to city-based boats that provide rural fishers

286 g indices for the PDO and AO, as well as the declining trend, can account for the interannual variabi

287 These declining trends appear to be driven by decreasing regio

288 in filter placement followed by significant declines (unadjusted reductions in VCF placement rates,

289 heory and models posit that C mineralization declines under elevated moisture and associated anaerobi

290 ociated estimated glomerular filtration rate decline was observed starting a decade later in life in

291 RNA correlated at baseline and when 9-month declines were compared, suggesting that these compartmen

292 e most extreme emissions scenario, projected declines were highly variable among reefs, ranging 10-10

293 Immune responses to influenza vaccines decline with age, reducing clinical effectiveness.

294 nd snow depth, both of which are expected to decline with climate change.

295 In bone marrow MSCs, FOXP1 expression levels declined with age in an inverse manner with those of the

296 Air CO2 Enrichment site showing that the CFE declined with increasing drought stress.

297 effective population sizes and gene flow all declined with increasing elevation, resulting in substan

298 tinuity between the proximal and distal ends declines with age.

299 e revealed that the E/I ratio systematically declines with increasing stimulus contrast or size.

300 Since the anomalous current declines with postnatal age, PIEZO2 may contribute to ha