ライフサイエンスコーパス: decondensation

1 elongation and heat shock-induced chromatin decondensation.

2 these proteins was associated with chromatin decondensation.

3 n the paternal compartment as early as sperm decondensation.

4 ion, and Cdk2 inhibitors reduce the level of decondensation.

5 ith this locus induces large-scale chromatin decondensation.

6 l II pausing, and Pol II-dependent chromatin decondensation.

7 d TRRAP involved in chromatin remodeling and decondensation.

8 lian genome results in large-scale chromatin decondensation.

9 receded by histone acetylation and chromatin decondensation.

10 nuclear histone citrullination, and nuclear decondensation.

11 ism for chlamydial nucleoid condensation and decondensation.

12 ells leading to p38 MAPK-dependent chromatin decondensation.

13 driven at least in part by global chromatin decondensation.

14 lacement from chromatin and global chromatin decondensation.

15 with paternal Ube3a silencing and chromatin decondensation.

16 e hypoosmotic conditions (100 mOsm/kg) cause decondensation.

17 ay, and it significantly increases chromatin decondensation.

18 al histone modification but rather chromatin decondensation.

19 ci within heterochromatin and leads to their decondensation.

20 us for transcriptionally regulated chromatin decondensation.

21 ation of histones by PAD4 mediates chromatin decondensation.

22 oscillations of chromosome condensation and decondensation, activation and inactivation of NIMA and

23 al protein 16) possess large-scale chromatin decondensation activity but minimal transcriptional acti

24 obic peptide motif had large-scale chromatin decondensation activity comparable to the strongest full

25 The chromatin decondensation activity did not require transcriptional

26 e, we demonstrate that large-scale chromatin decondensation activity is a general property of acidic

27 Specifically, LB3T inhibits chromatin decondensation and blocks the formation of both the nucl

28 protects sperm nuclei undergoing genome-wide decondensation and chromatin assembly from becoming abno

29 ntraction is associated with local chromatin decondensation and derepression of the DUX4 retrogene.

30 , KRP5 overexpression increases chromocenter decondensation and endoreduplication in the Arabidopsis

31 l an apparent incoordination between granule decondensation and exocytosis in the CF goblet cells.

32 Chromatin decondensation and hyperresponsiveness to TCR stimulatio

33 ord116, corresponding to increased chromatin decondensation and inhibition of Ube3a-ATS expression.

34 owever, HSR DNA replication is preceded by a decondensation and movement of the HSR into the nuclear

35 ack control mechanism that delays chromosome decondensation and NER in response to incomplete chromos

36 veillance mechanism that prevents chromosome decondensation and NER until effective separation of sis

37 racted this gradient and promoted chromosome decondensation and NER.

38 which lack the enzyme allowing for chromatin decondensation and NET formation, were evaluated.

39 e histones, a process required for chromatin decondensation and NET formation.

40 However, the significance of nuclear decondensation and NET generation in thrombosis is large

41 The injection inhibited chromosome decondensation and nuclear envelope formation.

42 , wild-type BAF completely blocked chromatin decondensation and nuclear growth.

43 entrations, wild-type BAF enhanced chromatin decondensation and nuclear growth; at higher added conce

44 otic-associated phosphorylations, chromosome decondensation and nuclear membrane reformation.

45 We conclude that Hoxb chromatin decondensation and nuclear re-organisation is regulated

46 ne or more events that occur after p40 locus decondensation and nucleosome remodeling and after, or i

47 phorylation of egg nucleoplasmin slows sperm decondensation and prevents basic protein removal from s

48 ures after fertilization, i.e. sperm nuclear decondensation and protamine-histone exchange.

49 ture and transcriptional impact of chromatin decondensation and reveal an unexpected role for Myc in

50 omal DNA undergoes replication, condensation-decondensation and segregation, sequentially, in some fi

51 portant regulator of chromosome condensation/decondensation and that disruption of the MCPH1-SET inte

52 introduction of chromatin prevents chromatin decondensation and the assembly of the lamina, membranes

53 olymerization is required for both chromatin decondensation and the binding of nuclear membrane precu

54 Post-anaphase events such as chromosome decondensation and the next round of DNA replication wer

55 inhibitor staurosporine inhibited chromatin decondensation and these epigenetic modifications with t

56 Acetylation is correlated with chromatin decondensation and transcriptional activation, but its r

57 inates H3R26, which leads to local chromatin decondensation and transcriptional activation.

58 cells undergoes a programmed heterochromatin decondensation and transcriptional reactivation of trans

59 Cdk2 is recruited to sites of Cdc45 decondensation, and Cdk2 inhibitors reduce the level of

60 , resulting in H1 phosphorylation, chromatin decondensation, and facilitation of fork progression.

61 asters from the spindles, blocked chromosome decondensation, and inhibited telophase chromosome movem

62 r models of histone storage, sperm chromatin decondensation, and nucleosome assembly.

63 , a prevalent mark associated with chromatin decondensation, and transcription factor p53 on K120, wh

64 ght to have a role in chromatin condensation/decondensation, and we asked whether ionizing radiation

65 o loss of CenH3; centromeric heterochromatin decondensation; and bulk activation of silent rRNA genes

66 Chromatin decondensation, another characteristic of Ag-experienced

67 However, looping out and decondensation are not simply two different manifestatio

68 on remains to be determined, the kinetics of decondensation are similar to the kinetics of poly(ADP-r

69 hromatin undergoes dramatic condensation and decondensation as cells transition between the different

70 mpromised in the H2Av null mutant, chromatin decondensation at heat shock loci is unaffected in the a

71 causes defects in the process of chromosome decondensation at late telophase.

72 structure and segregation, but not dramatic decondensation at metaphase.

73 polymerase II elongation-dependent chromatin decondensation at regions distal to DSBs.

74 e we show epigenetically regulated chromatin decondensation at snoRNA clusters in human and mouse bra

75 ir chromosomes during mid G2-phase and delay decondensation at the completion of mitosis.

76 ly through stabilizing R loops and chromatin decondensation at the paternally expressed PWS Snord116

77 These data suggested that chromatin decondensation away from the surface of chromosome terri

78 ced lymphocytes and demonstrated that FRA16D decondensation/breakage occurs over a region of at least

79 major mitotic exit events such as chromosome decondensation but nonetheless allowed chromosome disjun

80 Future molecular elucidation of chromatin decondensation by Npm will significantly contribute to o

81 nitored the kinetics of DNA condensation and decondensation by protamine 1 (P1) and synthetic peptide

82 ion axis and to prevent premature chromosome decondensation by retaining Condensin I.

83 xhibits Satb2 expression-dependent chromatin decondensation consistent with Satb2 being a target gene

84 ATPases RuvBL1/2 drive postmitotic chromatin decondensation, demonstrating that this is an active pro

85 neration by NADPH oxidase and also chromatin decondensation dependent upon the enzymes (PAD4), neutro

86 likely experience chromatin condensation and decondensation during a daily loading cycle.

87 endoribonuclease DICER facilitates chromatin decondensation during lesion recognition in the global-g

88 instead, the chromosomes underwent premature decondensation during mid-mitosis.

89 deiminase 4 (PAD4) correlates with chromatin decondensation during NET formation.

90 BAF also mediates chromatin decondensation during nuclear assembly.

91 tical for membrane recruitment and chromatin decondensation during nuclear assembly.

92 d cells where it mediates profound chromatin decondensation during the innate immune response to infe

93 Divalent ions counteract this decondensation effect by maintaining nucleosome stems an

94 Condensation and decondensation experiments with lambda-phage DNA show th

95 A second line affects the Decondensation factor 31 (Df31) gene, which encodes a pr

96 the cell cycle, accommodating for chromosome decondensation followed by genome duplication.

97 of multilobulated nuclei, as well as nuclear decondensation followed by membrane compromise, and were

98 the egg; snky sperm did not undergo nuclear decondensation, form a functional male pronucleus, or in

99 Upon decondensation, GAGA factor and Prod shift from low affi

100 Large-scale chromatin decondensation has been observed after the targeting of

101 noic acid (RA) induced large-scale chromatin decondensation in cells expressing RARalpha; however, ce

102 ination has important functions in chromatin decondensation in granulocytes/neutrophils.

103 Donut-shaped nuclei arise during chromatin decondensation in late mitosis; subsequently, cells with

104 e is known about the mechanisms of chromatin decondensation in somatic nuclei that do not contain con

105 nearly isometric expansion during chromosome decondensation in telophase and early G1.

106 ur results show that PAD4-mediated chromatin decondensation in the neutrophil is crucial for patholog

107 e DNA condensation in vitro exhibit nucleoid decondensation in vivo.

108 of 45S rDNA promoters as well as partial NOR decondensation, indicating that MAS2 negatively regulate

109 mor activity as single agents, the chromatin decondensation induced by histone deacetylase inhibitors

110 e measured the rates of DNA condensation and decondensation induced by the binding of Syrian hamster

111 then packaged within each cluster to enable decondensation into adjacent clusters.

112 through all stages of mitosis and chromatin decondensation into the G(1) stage of the next cycle.

113 , to chromatin is also effective at inducing decondensation involving phospho-H1.

114 We also demonstrate that postmitotic DNA decondensation is a gradual process, continuing for seve

115 ion of a noncentromeric LacO array, and this decondensation is modulated by the condensin II complex.

116 ranscriptional activation, but not chromatin decondensation, is sufficient to change replication timi

117 VPA-induced chromatin decondensation led to a sequence-specific potentiation o

118 Although this is optimal for storage, decondensation limits release.

119 ompanied by nucleolus organizer region (NOR) decondensation, loss of promoter cytosine methylation, a

120 key factor in stimulating synapsis, whereas decondensation may facilitate the invasion step and/or t

121 d that echinomycin interferes with chromatin decondensation, nuclear assembly and DNA replication.

122 In contrast, chromatin decondensation, observed during the early life cycle, ac

123 chaperone and assembly factor HJURP induces decondensation of a noncentromeric LacO array, and this

124 utation causing cytosine hypomethylation and decondensation of centromeres in interphase.

125 t localized adenosine triphosphate-dependent decondensation of chromatin at DSBs establishes an acces

126 erase 1 (PARP1) is responsible for the rapid decondensation of chromatin at sites of DNA damage.

127 ere Hoxd is also activated, there is visible decondensation of chromatin but no detectable movement o

128 This decondensation of chromatin correlates temporally with t

129 nown about the processes of condensation and decondensation of chromatin fibers.

130 oachment of euchromatin leads to detrimental decondensation of germline chromatin and germline mortal

131 ne lysine 9 trimethylation (H3K9me3) and the decondensation of global chromatin structure.

132 x that binds histones, thereby promoting the decondensation of higher-order chromatin structures.

133 Significant decondensation of large-scale chromatin structure, compa

134 ove along the DNA template without transient decondensation of observed large-scale chromatin "chromo

135 The atmorc1 and atmorc6 mutants show decondensation of pericentromeric heterochromatin, incre

136 An 8-fold allele-specific decondensation of snoRNA chromatin was developmentally r

137 However, the rate and extent of decondensation of sperm chromatin in egg extracts were n

138 Decondensation of sperm chromatin in eggs is explained b

139 NAP-1, but not dNLP, was able to promote the decondensation of sperm chromatin.

140 required for anaphase I, meiosis II, or the decondensation of the meiotic products.

141 and BRM resulted in chromatin remodeling and decondensation of the MMTV repeat as demonstrated by an

142 First, PLK1 triggers a decondensation of the MTOC structure.

143 1 signalling pathway also prevents chromatin decondensation of the sperm chromatin after pronuclear f

144 Consequently, the decondensation of the sperm nucleus does not occur.

145 They find that local decondensation of the template is accompanied by profoun

146 difficult to conceptualize without transient decondensation of these chromonema fibers.

147 lasmin performs the first stage of chromatin decondensation of Xenopus sperm at fertilization.

148 e assembly protein-1 (dNAP-1) to promote the decondensation of Xenopus sperm chromatin, a process tha

149 ed nuclear expansion (representing chromatin decondensation) of PMA-treated serpinb1-deficient neutro

150 Fragile sites appear as breaks, gaps, or decondensations on metaphase chromosomes when cells are

151 is altered intrinsically, inducing chromatin decondensation or cell differentiation.

152 ion potential: chromosome aneuploidy and DNA decondensation or damage are correlated with reproductiv

153 ation by JIL-1 is not required for chromatin decondensation or transcriptional elongation in Drosophi

154 side chromosome territories, and the visible decondensation or unfolding of interphase chromatin, are

155 not inhibit lamin polymerization, chromatin decondensation, or nuclear assembly and growth.

156 d to block Cyclin B3 destruction, chromosome decondensation, or nuclear membrane re-assembly.

157 oH2A is progressively lost during pronuclear decondensation prior to synkaryogamy.

158 Although sperm DNA decondensation proceeds without NPM2, abnormalities are

159 rm cells may undergo significantly different decondensation processes following fertilization.

160 Although the detailed mechanism of this decondensation remains to be determined, the kinetics of

161 extensive expansion of NE, further chromatin decondensation, restoration of the functionality, and sp

162 hese sequences did not prevent the spread of decondensation resulting from hsp70-lacZ transcription.

163 in the nucleus, where it regulates chromatin decondensation, RNA processing, and the phosphorylation

164 he general property of large-scale chromatin decondensation shared by most acidic activators is not s

165 y after photobleaching and caused chromosome decondensation similar to the effects of H1M depletion.

166 play a role in Hc1 degradation and nucleoid decondensation since it is expressed very early in the c

167 rotamine disulfide bonds ultimately leads to decondensation, suggesting that disulfide-mediated secon

168 ified an epigenetic inheritance of chromatin decondensation that maintained central nuclear positioni

169 rm components, for the asynchronous male DNA decondensation that occurs following intracytoplasmic sp

170 alian cells results in large-scale chromatin decondensation that strongly correlates with histone H1

171 s that PAD4 mainly plays a role in chromatin decondensation to form NETs instead of increasing histon

172 n 40-150 mM NaCl, a distinctive condensation-decondensation transition appears between 5 and 6 pN, co

173 f chromosome morphology revealed anisotropic decondensation upon digestion, with length increasing mo

174 ylation of RNA Pol I promoters and chromatin decondensation was apparent.

175 Neutrophil chromatin decondensation was assessed by measuring neutrophil fluo

176 Decondensation was blocked by two different drugs that i

177 The degree of decondensation was proportional to the amount of transcr

178 4 in mice), an enzyme important in chromatin decondensation, was elevated in neutrophils from individ

179 iminase 4, an enzyme that mediates chromatin decondensation, was identified to regulate both NETosis

180 apid ATP-dependent, ATM and H2AX-independent decondensation when DNA damage is introduced by laser mi

181 s, the donor nuclei exhibit global chromatin decondensation, which might contribute to reprogramming

182 c sperm injection resulted in abnormal sperm decondensation, with the unusual retention of vesicle-as

183 ion-condensation-segregation-(cell division)-decondensation-, with SCC of unspecified length.

184 bile Mcms is reduced together with chromatin decondensation within sites of active replication, which