ライフサイエンスコーパス: decondense

1 curs primarily in early G1 after chromosomes decondense.

2 present in high copy, the chromosomes do not decondense.

3 chromosome is severely distorted, appearing decondensed.

4 e site of integration, the chromatin remains decondensed.

5 During ES cell differentiation, decondensed alleles can also be found inside of chromoso

6 The chromatin in the oocyte quickly decondensed and a nucleus formed.

7 to either trypsin or proteinase K gradually decondensed and softened chromosomes but without entirel

8 primitive streak region: Hoxb chromatin was decondensed and the Hoxb1 locus looped out from its chro

9 n the presence of nocodazole-the chromosomes decondensed and the nuclear envelope re-formed-whereas c

10 entered an interphase-like state (chromatin decondensed, and an interphase-like microtubule array an

11 plicating mitotic chromosomes became visibly decondensed, and, after DNA replication was complete, th

12 We here show that stimulated lymphocytes decondense chromatin by three differentially regulated s

13 Here we found that Npm could widely decondense chromatin in undifferentiated mouse cells wit

14 e chromatin spreads revealed the presence of decondensed chromatin as gap structures along the spread

15 in contact to particulate agents to extrude decondensed chromatin as neutrophil extracellular traps

16 That is, the propagation of decondensed chromatin at specific loci through DNA repli

17 eed surrounded by or adjacent to a domain of decondensed chromatin composed of sequences from the gen

18 NETs are decondensed chromatin decorated by granular enzymes and

19 NETs consist of decondensed chromatin decorated with granular and cytoso

20 NETs are composed of decondensed chromatin decorated with granular proteins t

21 scs' are boundary elements that delimit this decondensed chromatin domain, reflecting the mechanism b

22 surrounding domains of recently transcribed decondensed chromatin have not.

23 se findings suggest that increased levels of decondensed chromatin in both normal progenitor cells an

24 ne hypercitrullination is detected on highly decondensed chromatin in HL-60 granulocytes and blood ne

25 form extracellular traps (NETs) by releasing decondensed chromatin lined with cytotoxic proteins.

26 26) modification colocalizes with ERalpha at decondensed chromatin loci surrounding the estrogen-resp

27 An open and decondensed chromatin organization is a defining propert

28 Taken together, we could visualize the decondensed chromatin regions together with active RNA p

29 ng sites, a transition from a condensed to a decondensed chromatin structure appears to take place.

30 layed after DNA replication, indicative of a decondensed chromatin structure in all regions of the re

31 on after replication and is facilitated by a decondensed chromatin structure.

32 e acquisition and heritable maintenance of a decondensed chromatin structure.

33 ochemical and bioimaging experiments suggest decondensed chromatin structures are associated with tra

34 ils trap and kill bacteria by forming highly decondensed chromatin structures, termed neutrophil extr

35 Peripheral blood neutrophils form highly decondensed chromatin structures, termed neutrophil extr

36 ocytes (PMNs), extrude molecular lattices of decondensed chromatin studded with histones, granule enz

37 tive genes may result from their location on decondensed chromatin that enables clustering around com

38 with probe penetration, (2) have relatively decondensed chromatin that is highly accessible to probe

39 on of neutrophil extracellular traps (NETs), decondensed chromatin threads decorated with cytoplasmic

40 r traps (NETs) resulting from the release of decondensed chromatin, were found to be part of the thro

41 ly, MEL-28 recruits PP1c to the periphery of decondensed chromatin, where it directs formation of a f

42 y reassembled a nuclear structure containing decondensed chromatin.

43 haracteristics including abundant amounts of decondensed chromatin.

44 a surrounding domain of recently transcribed decondensed chromatin.

45 for polymerase in producing and maintaining decondensed chromatin.

46 ced by recruitment of an acidic peptide that decondenses chromatin without affecting transcription, i

47 CTD charge reduction unfolds the domain and decondenses chromatin, a mechanism in consonance with re

48 Since PARP-1 decondenses chromatin, we hypothesize that this enzyme r

49 s depleted of Ca2+ and Mg2+ showed partially decondensed chromosomes and a loss of Topo II and ScII,

50 e viable only during slow growth and display decondensed chromosomes, suggesting that SMC complexes f

51 he entire perimeter of the region containing decondensing chromosomes in each daughter cell.

52 n daughter cells and rapidly associates with decondensing chromosomes in telophase, suggesting a role

53 Second, in telophase, decondensing chromosomes often moved rapidly (7-23 micro

54 mosome movement suggests that the surface of decondensing chromosomes, and by extension those of inta

55 , large-scale chromatin structures on Xa are decondensed compared with the Xi and transcription inhib

56 Transmigrated neutrophils also released decondensed DNA associated with proteases, which are kno

57 IL-1 dependent, and release of proteases and decondensed DNA from recruited neutrophils in the brain

58 were discovered as extracellular strands of decondensed DNA in complex with histones and granule pro

59 toxicity (i.e., the release of proteases and decondensed DNA triggered by phenotypic transformation d

60 arrest, appearance of convoluted nuclei with decondensed DNA, and formation of multinucleated cells.

61 The decondensed domain is enriched for the trimethyl H3K36 m

62 Formation of this decondensed domain requires transcription and topoisomer

63 to the more typical euchromatic regions that decondense during interphase.

64 ain specific regions of chromatin can become decondensed, even at physiological salt concentration, t

65 maternal IC, whereas the paternal IC is more decondensed, extending into the nuclear halo.

66 1-positive mass, but replication occurred at decondensed foci at the surface of this mass.

67 ytes arrest in a G(2) state based on uniform decondensed GV chromatin, interphase microtubule arrays,

68 of multinucleated giant cells and cells with decondensed, highly convoluted and lobulated nuclei that

69 nstrate that camphor causes the nucleoids to decondense in vivo and when the three genes are present

70 Remarkably, it decondenses in differentiating cells.

71 g the human alpha-globin genes is frequently decondensed, independent of transcription.

72 that facilitate chromosome segregation, and decondensed interphase structures that accommodate trans

73 exit mitosis, the neat rod-like chromosomes decondense into their interphase state.

74 with [3H]uridine autoradiography, shows that decondensed micronuclear chromatin undergoing active tra

75 ed to enhanced RNAPII transcription from the decondensed model chromatin.

76 conserved antimicrobial strategy comprising decondensed nuclear DNA and associated histones that are

77 These mutant embryos exhibit fragmented or decondensed nuclei and accumulate higher levels of SUMO-

78 ion of reactive oxygen species (ROS) and the decondensing of the nuclear DNA catalyzed by peptidyl ar

79 over, the free C-terminal domain can rapidly decondense ParB networks independently of its ability to

80 tability in MM may be associated with highly decondensed pericentromeric heterochromatin, which may p

81 We hypothesise that active, decondensed rDNA units are most likely to be deleted via

82 The XNP focus corresponds to an unusual decondensed satellite DNA block, and both active genes a

83 rified hyperphosphorylated egg nucleoplasmin decondense sperm chromatin and remove sperm basic protei

84 dhd-null embryos cannot decondense sperm chromatin and terminate development aft

85 iction-enzyme-mediated integration (REMI) on decondensed sperm nuclei followed by nuclear transplanta

86 Plasmids are introduced into decondensed sperm nuclei in vitro using restriction enzy

87 In Xenopus laevis, nucleoplasmin 2 (NPM2) decondenses sperm DNA in vitro.

88 on of the nuclear mitotic apparatus from the decondensing sperm nuclear apex.

89 onversion from a heavily compacted form into decondensed, spherical pronuclei, accompanied by rapid n

90 OMORPHOGENIC 1 maintain heterochromatin in a decondensed state in etiolated cotyledons.

91 one-containing chromatin fiber to exist in a decondensed state under conditions that normally would p

92 genes most frequently in association lie in decondensed stretches of chromatin.

93 exibility in vivo, maintaining a compact yet decondensed template that permits polymerase accessibili

94 Nucleoplasmin decondenses the sperm chromatin by removing protamines,

95 Decondensing the heterochromatin with 5-aza-2-deoxycytid

96 Here, we show that naive ES cells decondense their chromatin in the course of downregulati

97 tering mitosis, causing cells in prophase to decondense their chromosomes and return to G2 phase.

98 ay induces mid-prophase cells to transiently decondense their chromosomes, it is likely that it downr

99 treated with nocodazole, the majority (70%) decondensed their chromosomes and returned to G(2) befor

100 The mechanism by which chromatin is decondensed to permit access to DNA is largely unknown.

101 DNA fluorescent in situ hybridization (FISH) decondensed to varying degrees, in the most pronounced c

102 an immobilized polymerase molecule extrudes decondensed, transcribed sequences into its surroundings

103 Although these loci decondense upon HS, they do not undergo a detectable net