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1 nover were overrepresented in the genes with decreased expression.
2 l categories with significantly increased or decreased expression.
3 oters of stem cell genes, resulting in their decreased expression.
4 ctivation of resting T cells resulted in its decreased expression.
7 zoxazolamine-induced paralysis, secondary to decreased expression and activity of Cyp3a11 and Cyp2b10
9 Either intravenous or gastric loading led to decreased expression and activity of renal Pi transporte
11 ) replication of RSVand Sendai virus, due to decreased expression and secretion of type I and III int
12 pression is abnormal in psoriatic skin, with decreased expression correlating with recruitment of T-c
15 -C alleles that carry a C2 epitope, there is decreased expression frequency of the cognate receptor,
17 seq to identify a subset of transcripts with decreased expression in both nuclear and cytoplasmic fra
18 Persistent AF activity was associated with decreased expression in genes and gene sets related to i
19 Interestingly, there was also a trend for decreased expression in mild Alzheimer's disease hippoca
20 2 disease risk variants were associated with decreased expression in peripheral and mucosal tissues a
21 P = 0.0076), resulting mainly from slightly decreased expression in the ND and increased expression
22 ays p.i., approximately 28% of miRNAs showed decreased expression in the VEH/SIV group compared to no
24 apoptosis (IAPs) family member, exhibited a decreased expression level after DHM treatment, which ma
25 Immunohistochemistry revealed significantly decreased expression level of ADAM12 protein in the KBD
27 ermore, association between inflammation and decreased expression levels of MAGI3, PTEN, and TJP1 in
28 erologous CD8 T-cell proliferations, display decreased expression levels of PD-1 as well as PD-L1, an
30 classic M1 proinflammatory macrophages) and decreased expression levels of proinflammatory and profi
33 ted genes, and we confirm experimentally the decreased expression of 19 microRNAs with 11 correspondi
34 or of beta-1,3-glucan synthesis, for 21 days decreased expression of a broad panel of inflammatory ma
36 Moreover, IGF1R-deficient macrophages had decreased expression of ABCA1 and ABCG1 and reduced lipi
37 1ham2 RNA interference transgenic lines with decreased expression of acetyltransferases from the MYST
39 High-risk SMM patients showed at baseline decreased expression of activation-(CD25/CD28/CD54), typ
40 dition, western blot analyses show obviously decreased expression of active caspase-3 in methazolamid
42 of Sir2, Su(var)3-9, and Dicer-2, as well as decreased expression of Adar, mitigated age-related incr
43 ailure of negative selection, facilitated by decreased expression of Aire rather than impaired regula
45 ic N-methyl-D-aspartate (NMDA) receptors and decreased expression of alpha-amino-3-hydroxy-5-methylis
47 aginal cell DNA which may be associated with decreased expression of an estrogen-responsive gene.
48 d with OA derived extracellular vesicles had decreased expression of anabolic genes and elevated expr
49 lpha-Klotho in association with enhanced BP, decreased expression of angiotensin converting enzyme 2,
51 organ, leads to elevated cactus mRNA levels, decreased expression of antimicrobial peptides, and vuln
52 sufficient for infection in cell lines with decreased expression of antiviral IFN genes at baseline.
55 lung DCs (LDC), lung CD64(+) macrophages had decreased expression of B cell activation genes and indu
58 that the relA knockout strains demonstrated decreased expression of beta-hemolysin/cytolysin, an imp
60 ation of mTOR by leucine or deletion of TSC1 decreased expression of brown adipocyte-related genes UC
62 ORC1-mediated 4EBP1 phosphorylation leads to decreased expression of c-MYC and subsequent upregulatio
63 While downregulation of SALL4 leads to a decreased expression of c-Myc at both protein and mRNA l
66 ations have immature CD56(dim) NK cells with decreased expression of CD16, perforin, CD57, and impair
67 monocyte-derived macrophages, SSRI treatment decreased expression of CD4 (p < .0001) and CXCR4 (p = .
71 hepatic total cholesterol concentration and decreased expression of cholesterol metabolism related g
72 the data is indicated by the observation of decreased expression of claudin-1 and nuclear beta-caten
74 the phosphorylation of ERK, together with a decreased expression of cleaved caspase-3 in mice treate
75 y loss of interdigitating foot processes and decreased expression of components of the slit diaphragm
77 Reduced function of pTregs correlated with decreased expression of CTLA-4, interleukin-10, and tran
78 tion of G2/M progression was associated with decreased expression of cyclin A, cyclin B, cyclin E, cd
81 /G1-phase cell cycle arrest, as indicated by decreased expression of cyclins and CDKs and increased e
84 th the degeneration of DA axon terminals and decreased expression of DA neuron-enriched genes tyrosin
86 Infection with NiggV but not NiggA led to decreased expression of Dicer and Ago 2, suggesting that
87 Down-regulation of vaspin in KCs resulted in decreased expression of differentiation-associated genes
88 Taken together, our studies demonstrate that decreased expression of DMT1 in intestinal mucosa leads
89 erations in DNA methylation were apparent in decreased expression of DNA methyltransferase 3a and met
90 This phenomenon could be attributed to the decreased expression of DNA-protein kinase catalytic sub
95 videnced by increased rates of apoptosis and decreased expression of Eomes and Bcl2 early during the
97 on of proteolysis in endothelial cells, with decreased expression of extracellular matrix remodeling-
98 s downregulated in HCC patient specimens and decreased expression of FBP1 associated with poor progno
99 monstrated by reduced collagen abundance and decreased expression of fibronectin-1, collagen I, alpha
100 chors mGluR5 to the cell surface, as well as decreased expression of FKBP5, implicating aberrant gluc
102 ranscription factor CUX1, thereby leading to decreased expression of FTO and retinitis pigmentosa GTP
103 expressions of mitochondrial fission genes, decreased expression of fusion genes and synaptic genes
104 educing sensory glutamate release results in decreased expression of GABA-synthesizing enzymes GAD65
105 rsisted at 3 years but were characterized by decreased expression of genes associated with chronic im
106 correlation between loss of HF formation and decreased expression of genes associated with proliferat
108 ulation of ploidy changes is associated with decreased expression of genes controlling chromosome seg
109 olved in lipogenesis mediated by SREBP1c and decreased expression of genes involved in fatty acid bet
110 es6Delta, and ino80Delta mutants demonstrate decreased expression of genes involved in glycolysis and
111 nscriptional regulators TCF4 and NEUROD6 and decreased expression of genes involved in long-term pote
113 ssation of leaf and stem growth at anthesis, decreased expression of genes involved in stem cell wall
114 ssion of PU.1 in CD4(+) T cells and observed decreased expression of genes involved with the function
115 ed and control plants revealed significantly decreased expression of genes related to photosynthesis,
116 cathepsin S inhibitor or siRNA significantly decreased expression of growth differentiation factor-15
117 otective against asthma) was correlated with decreased expression of GSDMB in BEC and BAL (P = 1.3 x
119 paired SynT differentiation and specifically decreased expression of hCYP19A1, GCM1, and Fzd5, which
120 higher fasting insulinemia, concomitant with decreased expression of hepatic gluconeogenic genes.
122 osis, and the antiangiogenic factor GAX, and decreased expression of HIF-1alpha and proangiogenic fac
123 A GluR1 subunits and the neuronal GluT3, but decreased expression of hippocampal brain-derived neurot
125 eased protein expression of MUC16, SIRPA and decreased expression of HLA-DRB1 was further demonstrate
126 s, reduced colony-forming activity in vitro, decreased expression of Hox genes in the hematopoietic s
127 man immature DCs coinfected with HIV/Mtb had decreased expression of human leukocyte antigen antigen
132 filtration of leukocytes and macrophages and decreased expression of IL-6 were revealed in the muscle
133 ence of nuclear translocation of RelA with a decreased expression of IL-6, IL-12p40, and IL-17A.
134 mice is not due to defects in homeostasis or decreased expression of IL-7Ralpha, as transgenic expres
135 ortant for iNKT17 differentiation, including decreased expression of IL-7Ralpha, BATF and c-Maf and i
138 n species, attenuated elastin breakdown, and decreased expression of inflammatory cytokines and macro
140 ormality; however, VHR-knockout cells showed decreased expression of integrins and FAK but stronger F
144 d a profound loss of tissue differentiation, decreased expression of keratin 4 (KRT4) and cornulin (C
146 was induced in the KMT6(kd) strain, in which decreased expression of KMT6 is accompanied by reduced H
147 oupled with increased NF-kappaB activity and decreased expression of LC3, a hallmark of the autophagi
148 expression of fibrosis genes and remarkably decreased expression of let-7a and increased expression
151 ithelial V-like antigen (eva) expression and decreased expression of lipolytic enzymes (hormone-sensi
152 ls, increased lymphatic vessel leakiness and decreased expression of lymphatic specific markers compa
153 ctivation and increased granulocytes; and 4) decreased expression of lymphocyte related genes and lym
159 gakaryocytic differentiation, as revealed by decreased expression of megakaryocytic differentiation m
161 (Ly294002) of PI3K/AKT pathway significantly decreased expression of miR-21 and CSC markers and upreg
164 ransition showed metabolic shifts, including decreased expression of mitochondrial electron transport
165 thymoma viral oncogene homolog signaling and decreased expression of mitogen-inducible gene 6 (MIG6),
166 sd10 and Acaa2, and blunted VLDL export with decreased expression of Mttp and its product microsomal
168 unding the cuticle of the abdomen results in decreased expression of multiple HSR genes in proximal a
169 tients with recessive RYR1 mutations exhibit decreased expression of muscle-specific microRNAs, incre
170 ockdown resulted in increased E-cadherin and decreased expression of N-cadherin and snail transcripti
172 iology associated with neuroinflammation and decreased expression of neuronal activity marker, which
174 ear factor-kappaB (NF-kappaB) activation and decreased expression of NF-kappaB target genes matrix me
175 at the diagnosis of malignancy, including a decreased expression of NKp46 and decreased numbers of N
177 umor progression was more closely related to decreased expression of nuclear CDC25B than to changes i
178 We found that constitutive NIK expression decreased expression of numerous Treg signature genes an
179 of FEN1 and SUR4, increased ceramide levels, decreased expression of nutrient transporters, and induc
181 harmacologic inhibition of DOT1L resulted in decreased expression of oncogenic canyon-associated gene
182 ed optic nerve pathological states, we found decreased expression of one major metalloproteinase prot
183 rs and intramembranous bone formation and by decreased expression of osteoclastic markers and bone re
184 versely, adenovirus Dkk1-treated mice showed decreased expression of osteogenic markers, coupled with
185 rotizing enterocolitis patients also exhibit decreased expression of oxidative phosphorylation genes.
186 ased expression of ZFP871 is responsible for decreased expression of p53 in the PCBP4-deficient MEFs
188 ns This increase in survival correlated with decreased expression of pattern recognition receptors on
191 against melanoma in a syngeneic model, with decreased expression of PD-L1 and of matrix metallo-prot
193 mural cells, an effect that associated with decreased expression of PDGFRbeta and p57kip2, a cyclin-
194 arget of the Hippo pathway, which results in decreased expression of phosphatase and tensin homologue
195 M6/TRM61 mRNA and tRNAi(Met) expression with decreased expression of PKCalpha mRNA was detected in hi
196 d pathology impaired histone acetylation and decreased expression of plasticity genes, while aging al
197 dominal aortic aneurysms and correlated with decreased expression of predicted miR-181b targets, tiss
198 dominal aortic aneurysms and correlated with decreased expression of predicted miR-181b targets, tiss
199 t under glucose deprivation (GD) conditions, decreased expression of presenilin 1 (PS1) results in de
200 BS microbiota had reduced DSS colitis with a decreased expression of pro-inflammatory cytokines from
201 induces NEFM, RET, and VACHT and results in decreased expression of proapototic (BMF, BIM), adrenerg
203 pression of IL-10, IL-17, and granzyme B and decreased expression of programmed death 1 on these cell
204 D8(+) T cells with an effector phenotype and decreased expression of programmed death receptor-1 (PD-
206 This enhanced adhesion was associated with decreased expression of protein kinase A regulatory subu
207 and DNA replication and damage repair, and a decreased expression of proteins responsible for core ex
210 blocks primitive hematopoiesis, as shown by decreased expression of pu.1, mpo, and l-plastin; and di
211 ocalization and decrease in visual pigments, decreased expression of retinoic acid-responsive genes a
212 induction of interferon-stimulated genes and decreased expression of ribosomal proteins and translati
213 tient specimens revealed correlation between decreased expression of RKIP and increased expression of
217 ngevity pathways exhibit small nucleoli, and decreased expression of rRNA, ribosomal proteins, and th
218 ells (definitive hematopoiesis), as shown by decreased expression of runx1 and c-myb However, adtrp1
219 in differentiating neural cells we observed decreased expression of schizophrenia-associated gene Fe
221 ts and APTX-depleted Hela cells is caused by decreased expression of SDHA and genes encoding CoQ bios
222 ts with OA undergoing total knee replacement decreased expression of senescent and inflammatory marke
223 sponses to GA and brassinosteroid and showed decreased expression of several common target genes of D
224 Ductal cells exhibit aberrant polarity and decreased expression of several cystic disease genes, so
225 ion, deletion of this region in HEK293 cells decreased expression of several of the same genes that w
226 in number and density of synaptic vesicles, decreased expression of several presynaptic proteins, an
227 on showed DDR1 silencing was associated with decreased expression of several ribosomal proteins and e
230 blocked the activation of primary HSCs, with decreased expression of smoothened, GLI2 and ILK compare
231 The altered lipid content was attributed to decreased expression of sn-1,2 diacylglycerol acyltransf
232 ted substantial activation of p53 and STAT3, decreased expression of SOCS7, and increase in profibrot
233 t was also demonstrated that c-Myc knockdown decreased expression of Sp TFs and STAT3 These results d
235 s-of-function mutations in STAG2, as well as decreased expression of STAG2 or STAG3 proteins in sever
236 wnstream effector, STAT3, which leads to the decreased expression of STAT3 target genes that are asso
238 terferon-gamma, and fractalkine as well as a decreased expression of synaptophysin, a neuronal activi
241 with a shRNA against TCP80 not only exhibit decreased expression of TCP80 and RHA but also display d
242 eads to increased mature let-7, which causes decreased expression of TGF-betaRI, TGF-betaRIII, and SM
245 sverse aortic constriction, corresponding to decreased expression of the angiogenic factor VEGF.
246 ed inflammation under high-SS conditions and decreased expression of the antiinflammatory factor KLF-
247 l BA, colonocytes from WD-fed mice exhibited decreased expression of the BA transporters FABP6, OSTbe
249 rliest signaling alterations in CRC, and the decreased expression of the bile acid apical transporter
250 mponent protein expression, they demonstrate decreased expression of the calcium-dependent protein ki
251 ystem (UPS) was detected which resulted in a decreased expression of the deubiquitinating enzyme USP1
252 ity associated with infection sites, and had decreased expression of the early auxin responsive gene
253 pressive Tregs in the injured myocardium and decreased expression of the gene encoding IFN-gamma, a k
254 t of rapamycin complex 1 (mTORC1) signaling, decreased expression of the glucose transporter Glut1 an
255 specification of hemangioblasts, as shown by decreased expression of the hemangioblast markers, etsrp
256 n mice is cell intrinsic and associated with decreased expression of the high affinity IL-2 receptor
257 lation of histone H3, which coincided with a decreased expression of the histone deacetylase HDAC2.
258 ed CAR T cells (CTL019), in association with decreased expression of the immunosuppressive molecule p
260 s and microglial accumulation accompanied by decreased expression of the LPC receptor G2A, whereas MS
261 horylated SMAD2/3 (p-SMAD2/3) and NFATC2 and decreased expression of the major matrix-related genes S
262 The increase in PP2A activity is caused by decreased expression of the MID1 ubiquitin ligase that m
263 normal human diploid fibroblasts results in decreased expression of the mTOR inhibitor DDIT4 (REDD1)
264 city to use glycolysis, a function linked to decreased expression of the NAD(+)-dependent protein dea
268 xpression of the anti-oxidant marker CAT and decreased expression of the pro-oxidant marker NOX-4.
269 ic cells with dinaciclib resulted in rapidly decreased expression of the prosurvival protein Mcl-1, a
271 ng in cystinosis was found to associate with decreased expression of the small GTPase Rab11 and the R
272 miscarriage is associated with significantly decreased expression of the T-cell co-receptor CD8 and t
275 , reduced inflammation and eosinophilia, and decreased expression of the Th2 cytokine IL-13 and the l
276 30% decrease in transepithelial resistance, decreased expression of the tight junction scaffold prot
280 impaired TEC maturation and function such as decreased expression of thymotropic chemokines, decrease
282 ession of matrix metalloproteases as well as decreased expression of tissue inhibitor of metalloprote
283 in mtDNA, and impaired neuritogenesis with a decreased expression of transthyretin, which is known to
284 tective against asthma) were correlated with decreased expression of TSLP in BAL (P = 7.9 x 10(-11) a
285 d activation of microglia and astrocytes and decreased expression of tyrosine hydroxylase in periglom
287 revealed a decreased copy number of UT2 and decreased expression of UT2 in genomic and transcriptomi
288 pression of E-cadherin and beta-catenin, and decreased expression of vimentin and snail, which is par
289 ction, GYY4137 treatment was associated with decreased expression of viral proteins and mRNA, suggest
292 r medullary collecting duct 3 (mIMCD3) cells decreased expression of Wnt11, Krt23, and Slo4c1 DUSP8 o
293 we show that disruption of HNF4alpha caused decreased expression of XBP1 and reduced cellular ER net
294 del of uninephrectomy, RCH is accompanied by decreased expression of ZO-2 and nuclear expression of Y
295 y, volume fraction, and bone formation rate; decreased expressions of osterix, collagen I, and osteoc
296 ite branches and total neurite length, and a decreased expression on RhoA and neurodegenerative prote
297 , for a subset of genes showing increased or decreased expression, the respective gain or loss of H3K
298 , when FOXP1 protein expression was nuclear, decreased expression was also associated with favorable
300 xcitatory and inhibitory synaptic genes show decreased expression with age and are positively correla
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