ライフサイエンスコーパス: deep brain stimulation

1 raphy (during concurrent subthalamic nucleus deep brain stimulation).

2 may contribute to the therapeutic effects of deep brain stimulation.

3 nd lateral motor areas was not influenced by deep brain stimulation.

4 l open the door for novel therapies, such as deep brain stimulation.

5 severe refractory adults, psychosurgery and deep brain stimulation.

6 hese patients should still be considered for deep brain stimulation.

7 than current approaches such as lesioning or deep brain stimulation.

8 ht into targeting strategies for therapeutic deep brain stimulation.

9 s for feedback control in trials of adaptive deep brain stimulation.

10 s from 19 PD patients undergoing surgery for deep brain stimulation.

11 ulation may subvert the clinical efficacy of deep brain stimulation.

12 rmacological dopamine replacement therapy or deep brain stimulation.

13 , through drug discovery and new targets for deep brain stimulation.

14 ase (PD), and (iii) in PD during therapeutic deep brain stimulation.

15 fluid drainage, vagal nerve stimulation and deep brain stimulation.

16 rimotor urges, and (2) the TS treatment with deep brain stimulation.

17 ftereffects were not observed with classical deep brain stimulation.

18 e invasive experimental options like that of deep brain stimulation.

19 odes implanted in the subthalamic nuclei for deep brain stimulation.

20 put synchrony onto the cortex, is altered by deep brain stimulation.

21 fective, and it is less invasive compared to deep brain stimulation.

22 rary lead externalization during surgery for deep brain stimulation.

23 and that these symptoms are treatable using deep brain stimulation.

24 transcranial direct current stimulation, and deep brain stimulation.

25 ons between the therapeutic effectiveness of deep brain stimulation (3 months postoperatively) and de

26 skinesias, and underwent subthalamic nucleus deep brain stimulation 8 years after grafting.

27 Adaptive deep brain stimulation (aDBS) uses feedback from brain s

28 Deep brain stimulation allows drastic reduction of dopam

29 tonia can be effectively treated by pallidal deep brain stimulation although the mechanism of this ef

30 cted by neurosurgical interventions, such as deep brain stimulation and cingulotomy.

31 de other sophisticated treatments, including deep brain stimulation and gene therapies.

32 This so-called deep brain stimulation and other methodological advances

33 in depression and the mechanism of action of deep brain stimulation and perhaps chemical antidepressa

34 Physiologic therapies, including deep brain stimulation and transcranial magnetic stimula

35 Patients performed the tasks ON or OFF deep brain stimulation and/or ON or OFF dopaminergic the

36 lation, epidural electrical stimulation, and deep brain stimulation, and (4) technologies on the hori

37 anatomical circuits modulated by subthalamic deep brain stimulation, and infer about the inner organi

38 terpreting orofacial movements evoked during deep brain stimulation, and neuroimaging tractography ef

39 romodulation interventions, both invasive as deep brain stimulation, and non-invasive such as repetit

40 support the adjunctive use of neuroleptics, deep-brain stimulation, and neurosurgical ablation for t

41 Although the targets of deep brain stimulation are grey matter structures, axona

42 erventions, such as intrathecal baclofen and deep brain stimulation, are promising options.

43 high beta frequency range, but the degree of deep brain stimulation-associated suppression in their c

44 but in some cases surgical intervention with deep brain stimulation becomes necessary to alleviate mo

45 We simulated the effects of subthalamic deep brain stimulation both proximally to the stimulatio

46 particularly relevant given recent data from deep brain stimulation, both for neurologic and psychiat

47 Recent consensus guidelines explain when deep brain stimulation can be considered for severe refr

48 Deep brain stimulation can provide striking tremor relie

49 While typically highly effective, deep brain stimulation can sometimes yield suboptimal th

50 elates with the degree of improvement during deep brain stimulation, compatible with the current view

51 her developed to reliably identify effective deep brain stimulation contacts and aid in the programmi

52 tivity for the volume of tissue activated of deep brain stimulation contacts was assessed using proba

53 a novel method to map behavioral effects of deep brain stimulation (DBS) across a 3-dimensional brai

54 herence could pave the way to more efficient deep brain stimulation (DBS) algorithms for tremor.

55 Deep brain stimulation (DBS) allows for direct recording

56 Deep brain stimulation (DBS) and cortical responsive sti

57 Emphasis was placed on deep brain stimulation (DBS) and randomized clinical tri

58 Deep brain stimulation (DBS) as a putative approach for

59 out the response of this dystonia subtype to deep brain stimulation (DBS) at the internal globus pall

60 Subthalamic nucleus (STN) deep brain stimulation (DBS) can improve motor complicat

61 e subthalamic nucleus (STN) in patients with deep brain stimulation (DBS) electrodes.

62 Whether deep brain stimulation (DBS) exerts its clinical benefit

63 allidus externa (GPe) in children undergoing deep brain stimulation (DBS) for dystonia and investigat

64 To explore the feasibility of deep brain stimulation (DBS) for intractable SIB seen in

65 mbic areas has arisen in patients undergoing deep brain stimulation (DBS) for neuropsychiatric disord

66 The experience with deep brain stimulation (DBS) for pain is largely based o

67 The benefit of deep brain stimulation (DBS) for Parkinson disease (PD)

68 pose a novel, closed-loop approach to tuning deep brain stimulation (DBS) for Parkinson's disease (PD

69 mparative studies of the efficacy of 'awake' deep brain stimulation (DBS) for Parkinson's disease (PD

70 Deep brain stimulation (DBS) for Parkinson's disease is

71 Based on the success of deep brain stimulation (DBS) for treating movement disor

72 Multiple open-label trials of deep brain stimulation (DBS) for treatment-resistant dep

73 Subthalamic nucleus (STN) deep brain stimulation (DBS) has been found to restore t

74 Deep brain stimulation (DBS) has been proposed as a trea

75 Deep brain stimulation (DBS) has been used to treat a va

76 multiple sclerosis tremor using lesioning or deep brain stimulation (DBS) has been variable.

77 Deep brain stimulation (DBS) has emerged as a powerful s

78 Deep brain stimulation (DBS) has improved the prospects

79 Deep brain stimulation (DBS) has proven to be a safe and

80 Deep brain stimulation (DBS) has shown promise for treat

81 Deep brain stimulation (DBS) has virtually replaced abla

82 Deep brain stimulation (DBS) improves motor symptoms in

83 High-frequency deep brain stimulation (DBS) in motor thalamus (Mthal) a

84 We review the current application of deep brain stimulation (DBS) in Parkinson disease (PD) a

85 eus (PPTg) has been proposed as a target for deep brain stimulation (DBS) in parkinsonian patients, p

86 pplication in 1999, the potential benefit of deep brain stimulation (DBS) in reducing symptoms of oth

87 double-blind trial comparing active to sham deep brain stimulation (DBS) in the anterior limb of the

88 ical profiles, but both disorders respond to deep brain stimulation (DBS) in the same subcortical tar

89 Deep brain stimulation (DBS) is a clinical therapy used

90 Cortical deep brain stimulation (DBS) is a promising therapeutic

91 Accumbal deep brain stimulation (DBS) is a promising therapeutic

92 Deep brain stimulation (DBS) is a promising treatment fo

93 Deep brain stimulation (DBS) is a surgical procedure use

94 Deep brain stimulation (DBS) is a well-established modal

95 Deep brain stimulation (DBS) is an effective surgical tr

96 Deep brain stimulation (DBS) is an emerging intervention

97 Subcallosal cingulate white matter (SCC) deep brain stimulation (DBS) is an evolving investigatio

98 Deep brain stimulation (DBS) is currently being investig

99 se this feedback to control when therapeutic deep brain stimulation (DBS) is delivered.

100 Deep brain stimulation (DBS) is increasingly applied for

101 arge-balanced pulses used by the standard HF deep brain stimulation (DBS) is modulated by the smooth

102 Deep brain stimulation (DBS) is undergoing a transformat

103 Deep brain stimulation (DBS) is used to treat a number o

104 growing body of evidence demonstrating that deep brain stimulation (DBS) of globus pallidus internus

105 Deep brain stimulation (DBS) of subcallosal cingulate wh

106 dying the rewarding and punishing effects of deep brain stimulation (DBS) of subcortical emotional ne

107 Deep brain stimulation (DBS) of the subcallosal cingulat

108 The location of the optimal target for deep brain stimulation (DBS) of the subthalamic nucleus

109 Deep brain stimulation (DBS) of the subthalamic nucleus

110 Deep brain stimulation (DBS) of the subthalamic nucleus

111 Deep brain stimulation (DBS) of the subthalamic nucleus

112 Deep brain stimulation (DBS) of the subthalamic nucleus

113 Mechanisms whereby deep brain stimulation (DBS) of the subthalamic nucleus

114 morbid for a spectrum of sleep disorders and deep brain stimulation (DBS) of the subthalamic nucleus

115 Deep brain stimulation (DBS) of the subthalamic nucleus

116 Deep brain stimulation (DBS) of the subthalamic nucleus

117 ients failing ERP therapy are candidates for deep brain stimulation (DBS) of the ventral capsule/vent

118 Deep brain stimulation (DBS) of the ventral capsule/vent

119 Deep brain stimulation (DBS) of the ventral capsule/vent

120 n humans and rodents has explored the use of deep brain stimulation (DBS) of the ventral capsule/vent

121 Pi) in reward and punishment processing, and deep brain stimulation (DBS) of these structures has bee

122 Remarkably, deep brain stimulation (DBS) provides beneficial effects

123 Subthalamic nucleus (STN) deep brain stimulation (DBS) represents a well-establish

124 Closed-loop control is a promising deep brain stimulation (DBS) strategy that could be used

125 The risk of suicide behaviours post-deep brain stimulation (DBS) surgery in Parkinson's dise

126 basal ganglia of 15 patients with PD during deep brain stimulation (DBS) surgery of the bilateral ST

127 Deep brain stimulation (DBS) targeted at the nucleus acc

128 Deep brain stimulation (DBS) therapy has become an essen

129 ase (PD) patients' leukocytes pre- and post- Deep Brain Stimulation (DBS) treatment and compared to h

130 High-frequency deep brain stimulation (DBS) with a single electrical so

131 ement of focal lesions or the application of deep brain stimulation (DBS) within circuits that modula

132 Direct modulation of the NAS with deep brain stimulation (DBS), a surgical procedure curre

133 is divided into invasive approaches, such as deep brain stimulation (DBS), and noninvasive approaches

134 Parkinson's disease, on and off subthalamic deep brain stimulation (DBS), focussing on adaptive sens

135 leus (STN) or globus pallidus internus (GPi) deep brain stimulation (DBS), found that stimulation at

136 ith pallidotomy and then with high-frequency deep brain stimulation (DBS), has led to a renaissance i

137 lso survey recent progress in imaging-guided deep brain stimulation (DBS), imaging-based (neurofeedba

138 the nature of motor activity in response to Deep Brain Stimulation (DBS), in the mouse.

139 r difficulties in evaluating the efficacy of deep brain stimulation (DBS), or understanding its mecha

140 Chronic forniceal deep brain stimulation (DBS), recently shown to rescue h

141 When dyskinesia persists during therapeutic deep brain stimulation (DBS), the peak frequency of this

142 MRI studies and clinical procedures such as deep brain stimulation (DBS).

143 be accessed with surgical techniques such as deep brain stimulation (DBS).

144 n-human primate, swine, and rodent models of deep brain stimulation (DBS).

145 lation in some cases, was observed following deep brain stimulation (DBS).

146 t medical therapy (BMT, n=116) and bilateral deep brain stimulation (DBS, n=164) at either the subtha

147 vestigate the safety and targeting errors of deep-brain stimulation (DBS) electrodes placed under int

148 Furthermore, deep-brain stimulation (DBS) for psychiatric disorders t

149 plasticity induction by repeated pairing of deep-brain stimulation (DBS) of the BG with M1 stimulati

150 roaches are available such as capsulotomy or deep-brain stimulation (DBS).

151 treatment assignment, were implanted with a deep brain stimulation device and received their assigne

152 a control signal for closed-loop control of deep brain stimulation devices, for adjustment of dopami

153 Conventional deep brain stimulation did not change the distribution o

154 Furthermore, deep brain stimulation directed to the interposed cerebe

155 lia function, and new keys for understanding deep brain stimulation effects on cognitive and motivati

156 We hypothesized that driving deep brain stimulation electrodes at a frequency closely

157 We recorded from deep brain stimulation electrodes implanted bilaterally

158 end, we recorded local field potentials from deep brain stimulation electrodes implanted bilaterally

159 We recorded local field potentials from deep brain stimulation electrodes implanted in the STN i

160 ncephalogram and local field potentials from deep brain stimulation electrodes in 9 Parkinson's disea

161 otential (LFP) recordings from patients with deep brain stimulation electrodes in the basal ganglia h

162 nature of this interaction we recorded from deep-brain stimulation electrodes implanted bilaterally

163 sensorimotor cortex were identified in which deep brain stimulation-evoked activation correlated with

164 e presence of paraesthesias, the most common deep brain stimulation-evoked adverse effect.

165 ic resonance imaging could be used to detect deep brain stimulation-evoked changes in functional and

166 n stimulation (3 months postoperatively) and deep brain stimulation-evoked changes in functional and

167 In addition, our findings indicate that deep brain stimulation-evoked functional activation maps

168 ion localizations, followed by evaluation of deep brain stimulation-evoked therapeutic and adverse ef

169 a-amplitude in primary motor cortex and that deep brain stimulation facilitates motor improvement by

170 y in the SCC of 15 human subjects undergoing deep brain stimulation for depression while they viewed

171 cern regarding ventralis intermedius nucleus deep brain stimulation for essential tremor has been the

172 bus pallidus internus in patients undergoing deep brain stimulation for medically intractable primary

173 been implicated in the clinical benefits of deep brain stimulation for Parkinson's disease.

174 rom 16 hemispheres in 12 patients undergoing deep brain stimulation for severe dystonia using a speci

175 Moreover, based on our experience with Deep Brain Stimulation for treating obsessive-compulsive

176 selecting future strategies for closed loop deep brain stimulation for tremor control.

177 deep brain stimulation, whereas conventional deep brain stimulation globally suppressed beta activity

178 intrathecal infusion pumps, implantation of deep brain stimulation hardware, and general neurosurger

179 Deep brain stimulation has become an established means o

180 Deep brain stimulation has been Food and Drug Administra

181 While deep brain stimulation has been in the focus of academic

182 Deep brain stimulation has similar effects but requires

183 Among the invasive treatments, deep brain stimulation has the largest amount of existin

184 Transcranial magnetic stimulation and deep brain stimulation have emerged as therapeutic modal

185 High-frequency deep brain stimulation (HFS) is clinically recognized to

186 clinical status and therapeutic response to deep brain stimulation; however, suppression of the sens

187 effects was conducted in 9 adults undergoing deep brain stimulation implantation surgery for chronic

188 electrode screening session, one month after deep brain stimulation implantation, the clinical benefi

189 e, efficient and selective than conventional deep brain stimulation, implying mechanistic differences

190 underwent ipsilateral ventral tegmental area deep brain stimulation in a specialist unit.

191 patients treated with ventral tegmental area deep brain stimulation in an uncontrolled, open-label pr

192 Further, it is noted that deep brain stimulation in any brain target hitherto trie

193 Deep brain stimulation in epilepsy has targeted gray mat

194 lity of reward and choice during therapeutic deep brain stimulation in four patients with treatment-r

195 Both animal studies and studies using deep brain stimulation in humans have demonstrated the i

196 udies confirm lasting therapeutic effects of deep brain stimulation in isolated dystonia, good treatm

197 Deep brain stimulation in Parkinson's disease patients m

198 bthalamic nucleus-the most common target for deep brain stimulation in Parkinson's disease-in cost-be

199 ation in the motor cortex evoked ambulation, deep brain stimulation in the striatum caused rotation a

200 ous system for therapeutic purposes, such as deep brain stimulation in the treatment of Parkinson's d

201 ore efficacious than conventional continuous deep brain stimulation in the treatment of Parkinson's d

202 us epilepticus, suggesting a pivotal role of deep brain stimulation in the treatment response.

203 e target of neurosurgical lesions as well as deep brain stimulation in these patients.

204 These results suggest that thalamic deep brain stimulation in tremor likely exerts its effec

205 OCD and thus appears to be an alternative to deep-brain stimulation in selected cases.

206 Here, we explore deep brain stimulation-induced modulation of pathologica

207 7 weeks postoperatively, and one episode of deep-brain-stimulation-induced hypomania during the blin

208 While high-frequency deep brain stimulation is a well established treatment f

209 Deep brain stimulation is an established neurosurgical t

210 Deep brain stimulation is now the treatment of choice fo

211 raoperative testing of subcallosal cingulate deep brain stimulation is unknown.

212 Deep brain stimulation may be a treatment option in supe

213 Ventral tegmental area deep brain stimulation may be an effective treatment opt

214 anipulation of neural continence pathways by deep brain stimulation may offer new avenues for the tre

215 e pilot studies have suggested that adaptive deep brain stimulation may potentially be more effective

216 Deep brain stimulation may represent a viable alternativ

217 amic nucleus to its hyperdirect afferents by deep brain stimulation may subvert the clinical efficacy

218 e therapeutic and adverse effects induced by deep brain stimulation.media-1vid110.1093/brain/aww145_v

219 cacy, efficiency and selectivity of thalamic deep brain stimulation might be improved in this conditi

220 son's disease, and helps inform how adaptive deep brain stimulation might best be delivered.

221 ght exist in which activation resulting from deep brain stimulation might correlate with the presence

222 ecifically, we show that subthalamic nucleus deep brain stimulation modulates all the major component

223 ff treatment with either subthalamic nucleus deep brain stimulation (n = 14) or intravenous levodopa

224 Deep brain stimulation of anterior thalamus for partial

225 f individuals with anorexia nervosa in which deep brain stimulation of different brain areas resulted

226 study are illustrated by an index case where deep brain stimulation of estimated predominant non-moto

227 eted pharmacotherapy with Avpr1b agonists or deep brain stimulation of the CA2 are potential avenues

228 us that eventually resolved after commencing deep brain stimulation of the centromedian nucleus of th

229 the cerebral cortex associated with chronic deep brain stimulation of the cerebellar output, a treat

230 Deep brain stimulation of the globus pallidus internus a

231 solid evidence of the long term efficacy of deep brain stimulation of the globus pallidus pars inter

232 ndary generalised dystonia were treated with deep brain stimulation of the globus pallidus pars inter

233 ssive compulsive disorder who have undergone deep brain stimulation of the limbic and associative sub

234 Deep brain stimulation of the nucleus accumbens (NAc-DBS

235 sient behavior changes during intraoperative deep brain stimulation of the subcallosal cingulate and

236 Deep brain stimulation of the subthalamic nucleus (STN D

237 Recent evidence suggests that deep brain stimulation of the subthalamic nucleus (STN-D

238 n 13.3 +/- 6.3 years) who received bilateral deep brain stimulation of the subthalamic nucleus at the

239 Deep brain stimulation of the subthalamic nucleus is an

240 Deep brain stimulation of the subthalamic nucleus is an

241 rodes in Parkinson's disease patients, after deep brain stimulation of the subthalamic nucleus.

242 High frequency deep brain stimulation of the thalamus can help ameliora

243 Deep brain stimulation of the vALIC resulted in a signif

244 Ten patients receiving deep brain stimulation of the ventralis intermedius thal

245 gic tremors, and stereotactic destruction or deep brain stimulation of the ventrolateral thalamus has

246 Furthermore, this circuit could explain why deep brain stimulation of the zona incerta is beneficial

247 Previous case reports on deep brain stimulation of this region, now understood to

248 udy, we hypothesized that spatially targeted deep brain stimulation of ventromedial prefrontal cortex

249 Wireless deep brain stimulation of well-defined neuronal populati

250 We tested the hypothesis that deep-brain stimulation of the hippocampus or entorhinal

251 This finding might explain why deep-brain stimulation of the STN can impair subjects' a

252 etwork-disclosing the distributed effects of deep brain stimulation on cortico-subcortical connection

253 ting neuromodulation success and for guiding deep brain stimulation or other target-based neuromodula

254 h the long-term therapeutic effectiveness of deep brain stimulation (P < 0.05), with the strongest co

255 The latter could be exploited to improve deep brain stimulation, particularly if tremor suppressi

256 , respectively, and that subthalamic nucleus deep brain stimulation predominantly suppresses the form

257 rents-a radical departure from commonly used deep brain stimulation protocols-is sufficient to modula

258 the relatively selective effect of adaptive deep brain stimulation provides a rationale for why this

259 tem that tracks tremor phase to control when deep brain stimulation pulses are delivered to treat ess

260 Moreover, deep brain stimulation relatively selectively suppressed

261 te matter (WM) pathways, and the efficacy of deep-brain stimulation relies upon activation of WM.

262 Thalamic deep brain stimulation resulted in activation within est

263 lation is known to play an important role in deep brain stimulation's therapeutic mechanism.

264 lysis of responders to subcallosal cingulate deep brain stimulation (SCC DBS) for depression demonstr

265 Here, we demonstrate that deep brain stimulation selectively suppresses certain sp

266 pting information processing in the STN with deep brain stimulation should abolish the normalization

267 S.SIGNIFICANCE STATEMENT Subthalamic nucleus deep brain stimulation (STN DBS) is increasingly used in

268 Subthalamic nucleus deep brain stimulation (STN DBS) protects dopaminergic n

269 Bilateral subthalamic nucleus deep brain stimulation (STN-DBS) has been shown to impro

270 patients both on and off subthalamic nucleus deep brain stimulation (STN-DBS), while they performed a

271 hypothesis that pairing subthalamic nucleus deep-brain stimulation (STN-DBS) with motor cortical tra

272 While functional imaging and deep brain stimulation studies point to a pivotal role o

273 Although both adaptive and conventional deep brain stimulation suppressed mean beta activity amp

274 One hypothesis is that deep brain stimulation suppresses abnormally enhanced sy

275 hat clinically effective subthalamic nucleus deep brain stimulation suppresses synchrony locally with

276 se microelectrode recordings captured during deep brain stimulation surgery as participants engage in

277 mulation in the SN of 11 patients undergoing deep brain stimulation surgery for the treatment of Park

278 eurons (SPNs) in patients with PD undergoing deep brain stimulation surgery, compared with patients w

279 acy across different clinical indications of deep brain stimulation surgery.

280 ion will lead to improved interventions like deep brain stimulation, tailored to specific components

281 ucleus' portions deemed to be appropriate as deep brain stimulation target to treat motor symptoms in

282 Deep brain stimulation targeted to the vALIC.

283 n tremor should reveal the role of different deep brain stimulation targets in tremor generation.

284 longside with the growth of neuroimaging and deep brain stimulation techniques.

285 frequency-based design in the development of deep brain stimulation therapy for PD.

286 Deep brain stimulation therapy is an effective symptomat

287 Sustained locking of deep brain stimulation to a particular phase of tremor a

288 Deep brain stimulation to different targets has been pro

289 ecent behavioral experiments have shown that deep brain stimulation to the STN results in impulsivity

290 h Parkinson's disease undergoing surgery for deep brain stimulation to the subthalamic nucleus (STN)

291 ot study, we assessed safety and efficacy of deep brain stimulation to the supero-lateral branch of t

292 nson's disease and for pioneering the use of deep-brain stimulation to alleviate symptoms of the dise

293 Effective adaptive deep brain stimulation truncated long beta bursts shifti

294 Adaptive deep brain stimulation uses feedback about the state of

295 ases of epilepsy, current procedures such as deep brain stimulation, vagus, and trigeminal nerve stim

296 ut controlled antiparkinsonian medication or deep brain stimulation was allowed.

297 invasive neuromodulation therapies, notably, deep brain stimulation, where clinically relevant treatm

298 ive effect on burst duration during adaptive deep brain stimulation, whereas conventional deep brain

299 n the globus pallidus, a key target area for deep brain stimulation, which has not been mapped noninv

300 sed in the cochlear implant, bionic eye, and deep brain stimulation, which involves implantation of a