ライフサイエンスコーパス: deep sequencing

1 tin immunoprecipitation [ChIP] combined with deep sequencing).

2 imens for microRNA expression analysis using deep sequencing.

3 probes to enrich Illumina libraries prior to deep sequencing.

4 tuberculosis by applying UV-crosslinking and deep sequencing.

5 d the other of 12 genes, were used for ultra-deep sequencing.

6 [LDV/SOF arms], ION1, ION2, and ION3), using deep sequencing.

7 tio compared with similar methods leveraging deep sequencing.

8 expressed during lytic JMRV infection using deep sequencing.

9 ng chromatin immunoprecipitation followed by deep sequencing.

10 d identify aberrantly processed pre-mRNAs by deep sequencing.

11 l and the incidence of HCC was determined by deep sequencing.

12 100 bps), we analyzed the repair outcomes by deep sequencing.

13 analyzed these miRNAs using next-generation deep sequencing.

14 with pancreatic cancer were characterized by deep sequencing.

15 acute from chronic HCV infections utilizing deep sequencing.

16 8-G; P = 1.38 x 10(-9)) and was validated by deep sequencing.

17 hole-genome or exome sequencing and targeted deep sequencing.

18 th a combination of expression profiling and deep sequencing.

19 nd chromatin immunoprecipitation followed by deep sequencing.

20 DNA to be sorted to recover long targets for deep sequencing.

21 with zero transposon integrations in HPRT by deep sequencing.

22 cant for their use as reagents including for deep sequencing.

23 fied by analyzing reads from high-throughput deep sequencing.

24 ng chromatin immunoprecipitation followed by deep-sequencing.

25 rmed, in addition to bulk exome and targeted deep-sequencing.

26 constructed a cassava haplotype map through deep sequencing 241 diverse accessions and identified >2

27 ssion atlas of miRNAs and their promoters by deep-sequencing 492 short RNA (sRNA) libraries, with mat

28 Chromosome Conformation Capture followed by deep sequencing (4C-Seq) is a powerful technique to iden

29 Using mutation libraries and deep sequencing, Aakre et al. study the evolution of pro

30 by chromatin immunoprecipitation followed by deep sequencing, allowing for quantitative comparison of

31 Deep sequencing analyses have shown that a large fractio

32 Using GUIDE-seq and targeted deep sequencing analyses performed with both Cpf1 nuclea

33 Deep sequencing analyses revealed that [KIL-d] selective

34 Using microarray and deep-sequencing analyses, we found that galectin-7 posit

35 matin immunoprecipitation [ChIP] followed by deep sequencing) analyses in brown adipose tissue showed

36 yte miRNome and miRISC-associated miRNome by deep sequencing analysis of primary human chondrocytes.

37 We performed a deep sequencing analysis of rearranged immunoglobulin (I

38 Deep sequencing analysis of RNAs from such cells reveale

39 To study these mechanisms, we carried out a deep sequencing analysis of the transcriptome of spinal

40 Furthermore, deep sequencing analysis reveals that ZIKV populations i

41 Deep sequencing analysis showed that indomethacin exposu

42 High-throughput deep sequencing analysis with complete clinical validati

43 Using deep sequencing analysis, we investigated miRNA expressi

44 Deep-sequencing analysis confirmed that NS5B variants L1

45 Deep-sequencing analysis of B-cell lymphoma DNA confirme

46 n-TRAP-RiboTag approach in mouse that allows deep-sequencing analysis of ribosome-bound mRNAs in the

47 Furthermore, deep-sequencing analysis of TCR-beta (TRB) and TCR-alpha

48 ces of 23 HAdV-D8 isolates were generated by deep sequencing and analyzed phylogenetically.

49 Using deep sequencing and case-control genotyping studies, we

50 ng polymerase chain reaction (PCR), targeted deep sequencing and comprehensive analysis.

51 with the chromosome-wide "coat" observed by deep sequencing and conventional microscopy.

52 We used deep sequencing and electrophoretic mobility shift assay

53 rtion leads to the requirement of subsequent deep sequencing and extensive bioinformatics analysis.

54 Notably, RNA deep sequencing and functional analyses in HuR-deficient

55 ly developed the dsTbetaL method, which uses deep sequencing and in vitro selection of segments inser

56 This screening system does not require deep sequencing and may serve as a precedent for the app

57 affect caste in eusocial evolution, we used deep sequencing and Northern blots to isolate caste-asso

58 Deep sequencing and parallel analysis of RNA ends were u

59 s parallel positive selections combined with deep sequencing and statistical analysis and enables the

60 Using targeted deep sequencing and unbiased whole-genome off-target ana

61 ination of whole genome sequencing, targeted deep sequencing, and digital droplet PCR on matched diag

62 ene expression at 8 and 24 h was analyzed by deep sequencing, and the expression of interferon (IFN)

63 We used a sensitive gene-targeted deep sequencing approach to gain precision on the exact

64 e purpose of this investigation was to use a deep-sequencing approach to identify the effect of smoki

65 We used a deep-sequencing approach, together with neutralization p

66 Using a deep-sequencing approach, we determined TCRalpha- and TC

67 without a history of periodontitis through a deep-sequencing approach.

68 microbiome after treatment with EMD using a deep-sequencing approach.

69 Deep sequencing at a highly variable region of the P. vi

70 Deep sequencing based ribosome footprint profiling can p

71 Deep sequencing can detect somatic DNA mutations in tiss

72 NS5B sequence diversity assessed by deep sequencing can differentiate acute from chronic HCV

73 High-throughput "deep" sequencing can now measure this diversity in unpre

74 hnologies (bisulfite conversion, followed by deep sequencing) cannot distinguish between 5mC and 5hmC

75 sitivity of cancer personalized profiling by deep sequencing (CAPP-Seq) by about threefold, and syner

76 By deep sequencing cell-free DNA (cfDNA), isolated from cir

77 Chromatin immunoprecipitation followed by deep sequencing (ChIP-Seq) analysis of Sir proteins in T

78 Our chromatin immunoprecipitation with deep sequencing (ChIP-seq) analysis of the EBNA3 protein

79 Chromatin immunoprecipitation followed by deep sequencing (ChIP-seq) and ChIP-reChIP-seq analyses

80 Using EHF ChIP followed by deep sequencing (ChIP-seq) and RNA sequencing after EHF

81 ne chromatin immunoprecipitation followed by deep sequencing (ChIP-seq) datasets from postmortem brai

82 B9 chromatin immunoprecipitation followed by deep sequencing (ChIP-Seq) identified the c-Met inhibito

83 slinking and immunoprecipitation followed by deep sequencing (ChIP-seq), we found that DnaA was assoc

84 as chromatin immunoprecipitation followed by deep sequencing (ChIP-seq).

85 ng chromatin immunoprecipitation followed by deep sequencing (ChIP-seq).

86 atin immunoprecipitations (ChIP) followed by deep sequencing, ChIP-Seq, revealed that genome-wide bin

87 By applying ChIPac combined with deep sequencing (ChIPac-seq) to an established cell mode

88 rosslinking immunoprecipitation coupled with deep sequencing (CLIP-seq) we identify a set of genes in

89 ant analysis in SC x SI F2 individuals using deep sequencing confirmed that all SC plants were S1 hom

90 Targeted deep-sequencing confirmed AS-PCR findings, and identifie

91 Extensive experimental results on real ultra-deep sequencing data (8000x coverage) and simulated data

92 ovo genome assembly in the presence of ultra-deep sequencing data (i.e. coverage of 1000x or higher).

93 ase of fusion genes encompassing analysis of deep sequencing data and manual curations.

94 The application of correlation functions to deep sequencing data complements current evaluation sche

95 Here we use whole-genome deep sequencing data from 693 parents-offspring trios to

96 As a proof of concept, we generated deep sequencing data from a pool of 60 human cell lines;

97 dynamics of oncogenic mutations in targeted deep sequencing data from pre- and post-treatment leukem

98 By interrogating deep sequencing data generated from both packaged and un

99 large-scale mapping of the branchpoints from deep sequencing data in three different species and in t

100 Here, we describe a resource of deep sequencing data on parents and progeny from genetic

101 n existing approaches, particularly in ultra-deep sequencing data when high read counts for mutations

102 identifying transfer RNA (tRNA) fragments in deep sequencing data, evaluate them in the context of cu

103 r genetic variants for complex diseases with deep sequencing data, genomic marker sets of high-dimens

104 With the rapidly increasing volume of deep sequencing data, more efficient algorithms and data

105 develop a new method for inference using HIV deep sequencing data, using an approach based on importa

106 signed to archive the fusion candidates from deep sequencing data.

107 Interrogation of deep-sequencing data from MYB-overexpressing versus -sil

108 nza A virus (IAV) infections for which viral deep-sequencing data from transmission pairs are availab

109 Here, we use deep-sequencing data obtained from clinical samples coll

110 Deep-sequencing data provided additional diagnostic info

111 a new approach for determining thresholds in deep-sequencing datasets of short RNA transcripts.

112 CS sorting with large-scale quantitative IgH deep-sequencing demonstrate that B-1a IgH repertoire dif

113 Deep sequencing detected L159F in 15% (53 of 353) and V3

114 ins cumbersome relative to more conventional deep-sequencing experiments.

115 Deep sequencing facilitated identification of highly exp

116 Deep sequencing for BTK and PLCG2 was performed retrospe

117 S1 nuclease DNA:RNA immunoprecipitation with deep sequencing), for mapping hybrid-prone regions in bu

118 In this study, deep sequencing, genetic linkage analysis, and transcrip

119 tify high-dimensional sparse associations in deep sequencing genomic data of multi-ethnic individuals

120 in situ global RNA interactions with DNA by deep sequencing (GRID-seq), which enables the comprehens

121 To this end, we used deep sequencing (GRO-seq and PRO-seq) and analyzed nasce

122 Global run-on coupled with deep sequencing (GRO-seq) provides extensive information

123 to profile more than 1600 single HSPCs, and deep sequencing has enabled detection of an average of 6

124 Deep sequencing has identified CBFA2T3/GLIS2 and NUP98/K

125 Small RNA profiling using deep sequencing helped identify 22 novel miRNAs and 6 ge

126 ome conformation capture in conjunction with deep sequencing (Hi-C), we show that in Caulobacter cres

127 With deep sequencing, however, multiple viral mRNAs were dete

128 Here we perform deep sequencing in 360 primary breast cancers and develo

129 Chromatin immunoprecipitation followed by deep sequencing in Mll1-deficient cortical neurons revea

130 By microdissection and deep sequencing in mouse, we find that neural crest (NC)

131 By combining directed evolution with deep sequencing, it is now possible to generate sequence

132 ized method of preparing strand-specific RNA deep sequencing libraries from small RNAs and variably s

133 rging vaccine-related poliovirus variants by deep sequencing may aid in the poliovirus endgame and ef

134 These findings suggest that utilizing deep sequencing may improve prognostication during influ

135 ere we adopted a newly developed tag linkage deep sequencing method and analyzed the quasispecies of

136 Error analysis of the deep-sequencing method demonstrated reliable detection o

137 e therefore developed a culture-independent, deep-sequencing method targeting the 5' untranslated reg

138 is study, we employed a recently established deep-sequencing method termed Duplex Sequencing to condu

139 Using a deep-sequencing method to measure chromosomal exonucleol

140 Using specialized 3' end deep sequencing methods, we undertook a comprehensive an

141 epigenetic marks and chromatin structure by deep sequencing methods.

142 In this study, we used deep-sequencing methods to identify RNase L cleavage sit

143 Then, using deep-sequencing methods, we identified the host and vira

144 on, or (iii) technical errors/limitations of deep-sequencing methods.

145 4 SNPs and NS5A RAVs were analyzed including deep sequencing (n = 109) in an independent replication

146 We carry out deep sequencing of 13 additional inbred strains (BUB/BnJ

147 and lame (n = 12) chickens were analyzed by deep sequencing of 16S RNA genes.

148 lecular inversion probes for DNA capture and deep sequencing of 28 drug-resistance loci in M. tubercu

149 Through deep sequencing of 3' ends, we provide evidence that PAR

150 Here we report whole-exome and deep sequencing of 30 paired oesophageal adenocarcinomas

151 Deep sequencing of 64 synIXR SCRaMbLE strains revealed 1

152 other TFH-derived PTCL (n = 13) by targeted deep sequencing of a gene panel enriched in T-cell recep

153 Deep sequencing of a target site confirmed that Cas9 RNP

154 es during postnatal maturation by performing deep sequencing of accessible chromatin regions by using

155 such regions remain to be discovered through deep sequencing of adequately sized cohorts of patients.

156 astric microbiota analyses were performed by deep sequencing of amplified 16S rDNA.

157 Deep sequencing of autologous CAP257 viruses, however, r

158 Deep sequencing of cDNA corresponding to the IgH V-D-J r

159 After deep sequencing of cDNA, computational analysis yields f

160 Vbeta expression and deep sequencing of CDR3 revealed that in untreated HIV-1

161 ally those with advanced metastatic disease, deep sequencing of circulating cell free DNA (cfDNA) obt

162 sition on the upper arm of chromosome 5, and deep sequencing of DNA from these 13 lines gave five can

163 Deep sequencing of DNase-seq libraries and computational

164 Deep sequencing of embryonic stem cell RNA revealed many

165 Finally, deep sequencing of FXN pre-mRNA molecules revealed a pro

166 Deep sequencing of HIV reverse transcriptase (RT) was pe

167 bulin and T-cell receptor spectratyping, and deep sequencing of immunoglobulin heavy chain (IGH) and

168 Deep sequencing of LARP1-bound mRNAs reveal that non-pho

169 In conclusion, 454-deep sequencing of liver and plasma compartments in trea

170 Deep sequencing of lymphocyte receptor repertoires has m

171 Here, we report the deep sequencing of methicillin-resistant Staphylococcus

172 miR-seq (deep sequencing of miRNAs) data reveal that the degradat

173 Analysis by deep sequencing of mouse exonic loci containing A-to-I-e

174 Deep sequencing of MTAP/CDKN2A-CDKN2B loci in 77 periphe

175 In the human pathogen Candida albicans, deep sequencing of mutants lacking the orthologous prote

176 Deep sequencing of nasopharyngeal samples produced parti

177 Population-based sequencing and 454 deep sequencing of NS5B gene were performed on plasma an

178 Deep sequencing of nuclear RNA revealed a major fraction

179 Targeted deep sequencing of parental fibroblasts revealed that mo

180 Our study highlights the power of data from deep sequencing of pathogens as a component of outbreak

181 Using information from deep sequencing of patients with neurological or psychia

182 nes for reliable variant identification from deep sequencing of personal genomes.

183 n pluripotent cells in vivo, obtained by the deep sequencing of pre-implantation embryos.

184 Ultra-deep sequencing of resistant parasites identifies the sa

185 Deep sequencing of ribosome footprints (ribosome profili

186 information of mRNA in translation based on deep sequencing of ribosome protected mRNA fragments (RP

187 lation comprehensively and quantitatively by deep sequencing of ribosome-protected mRNA fragments.

188 Here, we show using deep sequencing of seven batches of vOka vaccine (includ

189 Deep sequencing of size-selected DNase I-treated chromat

190 In the present study, we performed deep sequencing of small RNA molecules in the embryonic

191 Using deep sequencing of small RNAs and CAGE of postnatal deve

192 Using deep sequencing of small RNAs, we followed the temporal

193 escence-activated cell sorting of a library, deep sequencing of sorted pools and downstream computati

194 Deep sequencing of Spo11 oligonucleotides demonstrates t

195 pp1 and spp3 revealed they were allelic, and deep sequencing of spp3 identified an independent disrup

196 Deep sequencing of strand-specific cDNA libraries is now

197 By extensive immune profiling and deep sequencing of TCR-beta V regions, two subsets of cT

198 Deep sequencing of TERC RNA 3' termini shows that PARN i

199 bination of flow cytometric cell sorting and deep sequencing of the 16S rDNA gene was used to charact

200 phocytes in combination with improvements in deep sequencing of the autologous cancer have provided n

201 Deep sequencing of the B-cell repertoires identified add

202 We propose that the information generated by deep sequencing of the BBCE cell lines coupled with phen

203 Deep sequencing of the BCR from E2-specific class-switch

204 To address this question, we performed deep sequencing of the BCR repertoire of AChR-MG, MuSK-M

205 We performed high-throughput deep sequencing of the beta-TCR repertoire in 29 lesiona

206 Deep sequencing of the gut microbiomes of 1135 participa

207 Quantitative deep sequencing of the Ig heavy chain locus from B220(+)

208 On deep sequencing of the IgH locus, TLR-responsive B cells

209 Deep sequencing of the NS3, NS5A, and NS5B regions were

210 Deep sequencing of the peptide-encoding inserts in the s

211 Deep sequencing of the renal transcriptome revealed sign

212 Deep sequencing of the same patient specimens identified

213 Deep sequencing of the tumor genome showed a highly hete

214 Ultra-deep sequencing of the viral genome was performed on 11

215 The latest deep sequencing of tumor genomes has reinforced the impo

216 Ultra-deep sequencing of two healthy-looking skin biopsies ide

217 tensive structural diversity arises, we used deep sequencing of wild populations to reveal genetic va

218 Small-RNA deep sequencing of WNV-infected mosquitoes indicated an

219 f these MYB-associated changes, we conducted deep-sequencing of transcriptome of MYB-overexpressing a

220 We performed deep sequencing on the T and B cells from patients recen

221 Through amplicon deep-sequencing placental malaria samples from women in

222 nd animal isolates of these three species by deep-sequencing polymerase chain reaction products ampli

223 r a 10-year period using a novel full-genome deep-sequencing process.

224 Labs without the means to undertake deep sequencing projects can mine the data available to

225 The application of mutational scanning and deep sequencing provides residue-level resolution of pos

226 Deep sequencing provides the ability to investigate clon

227 gene BCR-ABL1 Using bulk competitions with a deep-sequencing readout, we analyzed hundreds of mutatio

228 However, their characterization through deep sequencing remains challenging, in spite of rapid d

229 on takes approximately 4 d to complete, with deep sequencing requiring an additional approximately 4-

230 Furthermore, our targeted deep sequencing results confirmed that our adeno-associa

231 Second, deep sequencing revealed a pool of diverse epitope varia

232 T-cell receptor beta (TCRbeta) deep sequencing revealed a striking contraction of CD8(+

233 Deep sequencing revealed interpatient gp350 sequence var

234 Deep sequencing revealed minimal processing of TevCas9 p

235 Deep sequencing revealed that IGHV3-23*01 in Ramos cells

236 is and validation of sequences identified by deep sequencing revealed that specific cPTMs are signifi

237 icial linkages by primer extension, PCR, and deep sequencing reveals that a subtle interplay between

238 Furthermore, RNA deep sequencing reveals that this mechanism of altered g

239 Deep-sequencing reveals negligible off-target effects in

240 entify sisRNAs in Drosophila melanogaster by deep sequencing, reverse transcription polymerase chain

241 RNA deep sequencing (RNA-seq) has greatly facilitated the st

242 Deep sequencing (RNA-Seq) of RNA from undifferentiated a

243 RNA deep sequencing (RNA-seq) revealed that 94 transcripts w

244 Whole-fish deep sequencing showed genomic mutations associated with

245 miRNA deep-sequencing showed that human and rodent parathyroid

246 for inhibited cDNA synthesis, we developed a deep sequencing strategy to characterize nascent reverse

247 However, recent deep sequencing studies indicate that ubiquitin is highl

248 serving as a point of comparison with future deep-sequencing studies involving immune intervention.

249 Focusing on the results of a recent deep sequencing study of eyelid epidermis, we show that

250 assembly of short sequence reads produced by deep sequencing, such as de-novo assemblers, ignore the

251 With the rapid development of deep sequencing techniques in the recent years, enhancer

252 and posttreatment, but not on more sensitive deep sequencing techniques.

253 the litchi small RNA population with various deep-sequencing techniques and in-depth bioinformatic an

254 In the present study, we applied deep-sequencing techniques within a Bayesian hierarchica

255 With deep sequencing technologies, this question is taking on

256 ttenuated virus population and thus requires deep-sequencing technologies to explore the differences

257 Thanks to the development of deep-sequencing technologies, crop species have been tak

258 employed the next generation high-throughput deep sequencing technology to sequence all small RNAs an

259 The ABCA4 gene was analyzed by deep sequencing technology using a personal genome machi

260 Using deep sequencing technology, methods based on the sporadi

261 Using deep sequencing technology, we show that these ZFNs are

262 was firstly revealed in species level due to deep sequencing technology.

263 This study demonstrates how deep-sequencing technology can elucidate multiple mechan

264 ssay described here uses new developments in deep-sequencing technology combined with Primer ID-tagge

265 , and quantified particle biodistribution by deep sequencing the barcodes.

266 We used deep sequencing to characterize the between- and within-

267 We used deep sequencing to comprehensively follow viral evolutio

268 We use deep sequencing to define (i) transcriptomes of Brn3a- a

269 body and use X-ray crystallography and viral deep sequencing to describe how gp120 lacking glycans in

270 Here, we use deep sequencing to determine the types, rates and locati

271 , we performed bulked segregant analysis and deep sequencing to fine map it to an approximately 1 Mb

272 ghput mutagenesis, functional screening, and deep sequencing to identify mutations from a total of 7

273 ed chromatin immunoprecipitation followed by deep sequencing to identify the BCL6 binding sites on a

274 egmented amplification approach coupled with deep sequencing to profile DENV-3 intrahost diversity in

275 We developed an assay using Primer ID-tagged deep sequencing to quantify HIV-1 splicing.

276 matic single nucleotide variants obtained by deep sequencing to reconstruct multi-sample cell lineage

277 accessible genome in situ, cell sorting, and deep sequencing to reveal the identity of the imaged ele

278 -resistant viruses and used next-generation deep sequencing to reveal the order of relative fitness

279 By applying deep-sequencing to every passage of the virus, we are ab

280 ng single-genome amplification and Primer ID deep sequencing, to assess env genetic diversity of the

281 Using deep-sequencing transcriptomes, we identified several me

282 linearly to sequencing depth, enabling ultra-deep sequencing used to explore tumor evolution or detec

283 ciated microbiomes of the crop plant rice by deep sequencing, using plants grown under controlled con

284 Deep sequencing was applied to blood plasma samples from

285 apy because of disease progression, targeted deep sequencing was performed in samples at baseline and

286 Whole-genome deep sequencing was performed on isolates from the Canad

287 RNA deep sequencing was performed on the same samples in par

288 Deep sequencing was used to construct a fitness landscap

289 Utilizing deep sequencing we have generated 68.7 and 57.8 giga bas

290 Using deep sequencing, we analyzed a unique collection of long

291 Through deep sequencing, we found that loss of certain kinases r

292 bacterial surface-display, cell sorting, and deep sequencing, we have defined the specificities of th

293 and chromatin immunoprecipitation coupled to deep sequencing, we identified novel transcriptional tar

294 k chromatin immunoprecipitation coupled with deep sequencing, we mapped the enhancer and super-enhanc

295 gh-throughput competition assay, followed by deep sequencing, we measured a degradation potency index

296 droxymethylcytosine (5hmeC) distributions by deep sequencing, we show that PGCLCs derived from mouse

297 Combining single-molecule imaging and deep sequencing, we show that the budding yeast telomera

298 Using high-throughput exome- and/or deep-sequencing, we analyzed 103 chronologically acquire

299 s with the greatest enrichments based on the deep sequencing were validated to have higher affinity a

300 In this study, we describe a novel deep sequencing workflow using multiple polymerases to g