ライフサイエンスコーパス: defense against

1 erived reactive oxygen species, confers host defense against a broad spectrum of bacterial and fungal

2 uality of the inflammatory response and host defense against a gram-positive bacterial infection.

3 Innate immune defense against a highly antibiotic-resistant bacterial

4 nse to virus infection and thus mediate host defense against a range of DNA and RNA viruses.

5 tigated the IL-1 family member IL-33 in lung defense against A. fumigatus IL-33 was detected in the n

6 se-11 differentially contributed to the host defense against A. fumigatus infection and to endotoxemi

7 r macrophages play an essential role in host defense against acute lung injury.

8 the lung and play an important role in host defense against aerosol infection with microbial pathoge

9 dicates that persisters implement a positive defense against antibiotics prior to a passive defense v

10 naling plays an essential role in antifungal defense against Aspergillus fumigatus.

11 are known to play a pivotal role in the host defense against Aspergillus infections.

12 l, of MKP1's functions in PAMP responses and defense against bacteria.

13 are likely to contribute to mammalian immune defense against bacteria.

14 as been shown to play critical roles in host defense against bacterial and fungal infections at diffe

15 o sites of inflammation is essential for the defense against bacterial and fungal infections, but als

16 Neutrophils act as a first line of defense against bacterial and fungal infections, but the

17 al surfaces and are a critical first line of defense against bacterial and fungal pathogens.

18 response is a central element of the initial defense against bacterial and viral pathogens.

19 Two broad categories of defense against bacterial infection are resistance, cont

20 ivity, but the participation of PTEN in host defense against bacterial infection is less well underst

21 regulation of macrophage Nrp1 in host immune defense against bacterial infection remain unknown.

22 odies are thought to provide a first line of defense against bacterial infections and play a major ro

23 However, the role of type I IFNs in host defense against bacterial infections is enigmatic.

24 dings reveal that TRPC1 is required for host defense against bacterial infections through the TLR4-TR

25 Neutrophils are the first line of defense against bacterial infections, and the generation

26 g by human neutrophils, the primary cellular defense against bacterial infections.

27 thase-2 (NOS2) plays major functions in host defense against bacterial infections.

28 studies reveal a novel role of mast cells in defense against bacterial infections.

29 ic multiprotein complexes that initiate host defense against bacterial pathogens by activating caspas

30 nical inflammasome activation that initiates defense against bacterial pathogens in primary human mac

31 ese genes in nonhost resistance and stomatal defense against bacterial pathogens, respectively.

32 Inflammasomes are critical for host defense against bacterial pathogens.

33 We conclude that M-CSF is critical to host defenses against bacterial pneumonia by mediating surviv

34 as systems provide prokaryotes with adaptive defense against bacteriophage infections.

35 We test the theory that shame evolved as a defense against being devalued by others.

36 time the impact of a root endophyte on plant defense against below-ground herbivores, adds to growing

37 with respect to growth and morphogenesis and defense against biotic and abiotic stress.

38 oles in plant growth and development, and in defense against biotic and abiotic stress.

39 l functions, such as in hormone transport or defense against biotic and abiotic stresses.

40 revealing a trade-off between metabolism and defense against biotic stress.

41 that have been co-opted by bacteria for self-defense against both bacteria and eukaryotic cells.

42 l immune system represents the first line of defense against Brucella infection in nature.

43 hat B1a cells play an important role in host defense against C. burnetii infection in mice.

44 However, the role of neutrophils in the host defense against C. burnetii infection remains unclear.

45 t neutrophils play an important role in host defense against C. burnetii pulmonary infection.

46 ggest that the SK1-S1P pathway promotes host defense against C. neoformans infections by regulating c

47 ole of saliva in unifying host innate immune defenses against C. albicans as a communicating medium a

48 the notion that ATR plays a key role in the defense against cancer formation induced by PhIP and rel

49 is considered an important component in host defense against Candida infections and is modulated by C

50 liabilities by activating native host immune defenses against cells expressing the receptor antigens.

51 sensitive client proteins in a first line of defense against cellular stress.

52 ylaxis, and they play a pivotal role in host defense against certain pathogens.

53 17 or natural antibodies did not provide any defense against chronic P. aeruginosa infection.

54 ather than antibody is a key element in host defense against chronic pulmonary infection with P. aeru

55 rriage of bacterial food (proto-farming) and defense against competitors.

56 unity and an important element of antifungal defenses against cryptococcal infection and CNS dissemin

57 aggregation, in a manner similar to cellular defenses against cytosol-dwelling microorganisms.

58 s still unclear how xylem contributes to the defense against DED.

59 In contrast, TLR7 was important for defense against disease in the lungs.

60 id cells are, beside as the first barrier of defense against diseases, an excellent model system to i

61 However, the molecular basis of host defense against disseminated candidiasis remains elusive

62 enes (HLA-B and MAPK10) that are involved in defense against endemic pathogens such as malaria.

63 Defense against enemies is a type of natural selection c

64 The host mechanism of defense against enteric nematode infection remains to be

65 nic mucus barrier, which serves as a primary defense against enteric pathogens.

66 Defense against environmental threats is essential for a

67 ance available resources between building up defenses against environmental threats and initiating th

68 an essential role of Rif1 in the epigenetic defense against ERV activation.

69 ndangered Species Act is presumed to offer a defense against extinction and a solution to achieve rec

70 -17RA/IL-17RC receptor, is critical for host defense against extracellular bacterial and fungal patho

71 in 17 (IL-17) is a critical cytokine in host defense against extracellular pathogens, including S. pn

72 ling plays a crucial role in regulating host defenses against extracellular pathogens, particularly i

73 y loaded onto Argonaute, enabling DNA-guided defense against foreign DNA.

74 Defensins play an important role in plant defense against fungal pathogens.

75 cally prime distant plant parts for enhanced defense against future attack.

76 caspase-11 activation and is central to host defense against Gram-negative bacterial infections and t

77 from the intestine and is the first line of defense against gut-derived antigens, the effects of mic

78 ching, is an evolutionary warning system and defense against harmful environmental agents.

79 covered a new mechanism responsible for host defense against HCV infection, and could potentially aid

80 her they also function as generalized direct defenses against herbivores and pathogens remains unknow

81 ecific metabolites that function as indirect defenses against herbivores of the wild tobacco Nicotian

82 in regulating jasmonate perception and plant defenses against herbivorous insects and necrotrophic fu

83 s in mice indicate that IgE also can enhance defense against honeybee venom.

84 NK cells play a major role in immune defense against human and murine CMV (MCMV) infection.

85 Astrocytes are a primary defense against hyperexcitability, but their functional

86 NK cells are the first line of defense against infected and transformed cells.

87 Innate immunity provides an immediate defense against infection after host cells sense danger

88 T cells have a pivotal protective role in defense against infection and cancer but also are instru

89 T cells provide immune-surveillance and host defense against infection and cancer.

90 ces and represent the first line of cellular defense against infection and injury.

91 It represents the first line of defense against infection and is involved in tissue repa

92 pathway not only mediates protective immune defense against infection by a large variety of DNA-cont

93 al killer (NK) cells provide a first line of defense against infection via the production of antivira

94 Although this process is a defense against infection, NETosis can damage tissue.

95 ce suggests they have multiple roles in host defense against infection.

96 n and, thus, are predicted to provide potent defense against infection.

97 t and serves as the first line of intestinal defense against infection.

98 s represents the first line of intracellular defense against infection.

99 obicidal and modulatory roles in innate host defense against infection.

100 potentially reduce the efficacy of the host defense against infection.

101 nnate immune system that is involved in host defense against infection.

102 mmune cells, which also plays a role in host defenses against infection.

103 f immune cells is a vital cornerstone of our defense against infections and a key challenge of immuno

104 nnate immune system is responsible for early defense against infections and it is believed that the i

105 Collectively, PTI contributes to host defense against infections by a broad range of pathogens

106 ls are the immunological cornerstone in host defense against infections by intracellular bacterial pa

107 s exert major functions in immune tolerance, defense against infections, and anticancer immune respon

108 ll subsets in human lymphocyte biology, host defense against infections, and immune regulation.

109 molecules that play a major role in the host defense against infections, autoimmunity, and autoinflam

110 immunity, and by being a first layer in our defense against infectious agents, it is essential for o

111 onocytes and macrophages, is a first line of defense against infectious diseases and plays a key role

112 icates that cell death contributes to immune defense against infectious diseases.

113 the innate immune system, are important for defense against infectious pathogens and cancer.

114 suppress the host innate and acquired immune defenses against infestations.

115 iary beating, is the primary physical airway defense against inhaled pathogens and irritants.

116 feb (DeltaIEC)) to examine its importance in defense against injury.

117 jasmonic acid (JA) pathway and enhance their defense against insect herbivory.

118 ates plant responses to abiotic stresses and defenses against insect herbivores when they occur simul

119 aling regulates abiotic stress responses and defenses against insects, and discuss the few recent stu

120 e-induced cell death triggers a multifaceted defense against intracellular bacteria facilitated by tr

121 (IFN-gamma) is an essential mediator of host defense against intracellular pathogens, including the p

122 ly activated" phenotype that participates in defense against intracellular pathogens.

123 ) response and plays a critical role in host defense against intracellular pathogens.

124 r immune responses are a critical first-line defense against invading bacterial pathogens.

125 ophils constitute the first line of cellular defense against invading microorganisms and modulate the

126 l effects of complement as the first line of defense against invading microorganisms.

127 ocytic system that act as first line of host defense against invading pathogens but are also importan

128 te immunity where it forms the first line of defense against invading pathogens.

129 gammadelta T cells act as a first line of defense against invading pathogens.

130 ssociated molecular patterns to promote host defense against invading pathogens.

131 ophils are responsible for the first line of defense against invading pathogens.

132 ly of cytokines have important roles in host defense against invading viruses and bacteria.

133 are degradative compartments and one of the defenses against invading pathogens, they are also hubs

134 and linear oligo-nucleotide signals activate defenses against invasive nucleic acids in animal immuni

135 functions as an Fe(II) exporter and aids GAS defenses against iron intoxication and oxidative stress.

136 , cell types known to be important for early defenses against L. monocytogenes in the spleen, as well

137 ubiquinone acts as the cell's first line of defense against LCFA-induced oxidative stress.

138 intestinal microbiota provides nonredundant defense against lethal, disseminated infection.

139 lated pathogen-induced inflammation and host defense against Lm infection through modulating the TLR4

140 M-CSF-dependent mechanisms and enhances host defense against M. tuberculosis infection.

141 duction, and plays an important role in host defense against M. tuberculosis.

142 ls are an important component of host immune defense against malignancy and infection.

143 ng are essential for regulating mucosal host defense against many invading pathogens.

144 pecific NK cells and are beneficial for host defense against MCMV infection.

145 aevis embryo, is postulated to function as a defense against microbes.

146 serve as novel GPCR targets to modulate host defense against microbial infection.

147 d macrophages is emerging as a major line of defense against microbial infections and tumors.

148 al peptides (AMPs) play an important role in defense against microbial infections in insects.

149 nate immune system is the front line of host defense against microbial infections, but its rapid and

150 he innate immune system is critical for host defense against microbial pathogens, yet many pathogens

151 ost organisms during infection, supports the defense against microbial pathogens.

152 Immune defenses against microbial invasion are thus well develo

153 y metabolites that act as a chemical line of defense against microorganisms in the environment.

154 efensins may play a general role in mosquito defense against Microsporidia.

155 ith the PGE analog misoprostol improved host defense against MRSA skin infection by restoring DC migr

156 mechanisms of B cells and antibodies in the defense against Mtb infection.

157 e lysosomal engorgement in compromising host defense against mycobacteria.

158 of its OS epitopes, could contribute to the defense against mycobacterial infection in humans.

159 eptor 2 (TLR2) plays a critical role in host defenses against mycobacterial infections.

160 IFN-gamma is a critical mediator of host defense against Mycobacterium tuberculosis (Mtb) infecti

161 The relevance of antibodies (Abs) in the defense against Mycobacterium tuberculosis infection rem

162 Although the exact mechanisms of plant defense against nanotoxicity are unclear, several releva

163 in development, reproduction, longevity, and defense against natural enemies.

164 gated the role of plant toxins in nectar for defense against nectar robbers [4, 9, 10].

165 viral genome and provides long-term adaptive defense against new viral infection, expression and repl

166 ms to regulate subsets of genes required for defense against NO-induced nitrosative stress, and that

167 e surface area and functions as a first-line defense against noxious insults.

168 g cassette (ABC) transporter plays a role in defense against numerous pathogens and is recruited to s

169 One important line of defense against oropharyngeal candidiasis is the oral mi

170 ated factor 2 (NRF2), a critical mediator of defense against oxidative and electrophilic stress.

171 bility to store H2S in vivo and as a line of defense against oxidative stress, from which it is clear

172 is a critical regulator of genes involved in defense against oxidative stress.

173 33c's activity was consistent with a role in defenses against oxidative stress generated during host

174 r 2 (NRF2), a critical regulator of cellular defenses against oxidative stress.

175 elucidate a novel role for PPARgamma in host defense against P. aeruginosa Strategies that activate P

176 ffects of the propolis envelope as a natural defense against Paenibacillus larvae, the causative agen

177 findings implicate indole glucosinolates in defense against parasitic plants.

178 not only central to mounting an appropriate defense against parasitic worms, noxious substances, tox

179 ilies are important in wheat food use and in defense against pathogen attacks, respectively.

180 irway lumen to function as the first line of defense against pathogen encounter.

181 stinal mucous layer provides a critical host defense against pathogen exposure and epithelial injury,

182 gainst attack by microbes, but their role in defense against pathogen infection in woody plants has n

183 ype I interferons serve as the first line of defense against pathogen invasion.

184 ment activates responses that are central to defense against pathogenic attack.

185 Skin provides the first defense against pathogenic micro-organisms and is also c

186 As a front line of defense against pathogenic microbes, our body employs a

187 in many cellular interactions during immune defense against pathogenic organisms.

188 C) migration is essential for efficient host defense against pathogens and cancer, as well as for the

189 lthough inflammasomes are essential for host defense against pathogens and contribute to autoimmune d

190 of our digestive tract is the first line of defense against pathogens and damage.

191 rs and chromatin to induce transcription for defense against pathogens and environmental insults.

192 methylase 2) family protein, which modulates defense against pathogens and flowering time.

193 innate immune response is the first line of defense against pathogens and is orchestrated by the con

194 f functional capabilities important for host defense against pathogens and tumors.

195 n the control of cell-signaling pathways and defense against pathogens and whose imbalance leads to p

196 t hormone action, programmed cell death, and defense against pathogens have been attributed to ROS ge

197 ses involving KC represent the first line of defense against pathogens in the liver.

198 sident immune cells and function as the main defense against pathogens or injury.

199 een shown to be involved in the constitutive defense against pathogens through the secretion of toxic

200 Abs which provide an integral first line of defense against pathogens while also performing importan

201 In order to optimize the output of defense against pathogens with distinct lifestyles, plan

202 arious functions including oxidative stress, defense against pathogens, and metal homeostasis were im

203 h as the regulation of endogenous processes, defense against pathogens, and response to abiotic stres

204 ural killer (NK) cells are important in host defense against pathogens, and they can subsequently dif

205 have elucidated the functions of DCs in host defense against pathogens, autoimmunity, and cancer.

206 masome activation is critical for the host's defense against pathogens, but dysregulation of inflamma

207 es and macrophages provide the first line of defense against pathogens, but their roles in HCV infect

208 une systems in animals and plants as natural defense against pathogens.

209 gen species, which are required for the host defense against pathogens.

210 microbial peptides (AMPs) as a first line of defense against pathogens.

211 interferons have diametric roles in the host defense against pathogens.

212 in barrier epithelia provide a first line of defense against pathogens.

213 ate immune system provides the first line of defense against pathogens.

214 ival epithelial cells form the first line of defense against pathogens.

215 ntibodies provide an efficient first-line of defense against pathogens.

216 Inflammasomes are critical for mounting host defense against pathogens.

217 adaptive response that ensures an efficient defense against pathogens.

218 ole for XBAT35.2 in cell death induction and defense against pathogens.

219 Mast cells (MCs) are involved in host defenses against pathogens and inflammation.

220 development and provides insights into host defenses against pathogens and the immunological mechani

221 optosis is a form of cell death important in defenses against pathogens that can also result in a pot

222 tream signaling may reduce the host's innate defenses against pathogens, leading to bacterial persist

223 elial cells (AECs) form the key line of lung defenses against pathogens.

224 Plants have evolved an array of defenses against pathogens.

225 Bacteria can evolve constitutive defense against phage by modification/masking of surface

226 ated to the general stress response, such as defense against phages, growth control, biofilm formatio

227 use protein phosphorylation as part of their defense against phages.

228 inant human IL-7 (rhIL-7) would augment host defense against Pneumocystis and accelerate pathogen cle

229 n the crucial role of CD4(+) T cells in host defense against Pneumocystis, we used RNA sequencing of

230 monocyte-derived cells that are critical in defense against pneumonia, but mechanisms that regulate

231 are important for constitutive antimicrobial defenses against pneumonia.

232 hat B1a cells play an important role in host defense against primary C. burnetii infection.

233 ns are a key, nonredundant component of host defense against pulmonary infection with RSV, functionin

234 ne memory contributes to the protective host defense against recurring MRSA infection.

235 They constitute a defense against reinfection by pathogens, yet arguably d

236 Alveolar macrophages are the first line of defense against respiratory infections.

237 ivo Macrophages are a critical first line of defense against respiratory pathogens.

238 are abundant in the lung, but their role in defense against respiratory viruses is poorly understood

239 reaction to an unrelated antigen can enhance defense against Russell viper venom (RVV) and determined

240 IFN-independent mechanisms active in innate defense against RV, and demonstrate that even in the abs

241 r transport into the phagosome mediates host defense against S Typhimurium, which is counteracted by

242 ypothesis that platelets participate in host defense against S. aureus both through direct killing of

243 ty of mouse platelets to participate in host defense against S. aureus infection was determined by as

244 in deficiency impairs early pulmonary innate defense against S. aureus quorum-sensing-dependent patho

245 reveal novel targets to promote host innate defense against S. aureus skin infection.

246 d chemokines, CXCL1 and CXCL5, improves host defenses against S. pneumoniae.

247 ontains high numbers of neutrophils, the key defense against staphylococcal infection.

248 ncoded by NFE2L2, is the master regulator of defense against stress in mammalian cells.

249 rimed wheat (Triticum aestivum) for enhanced defense against subsequent infection with the hemibiotro

250 cate that PgMPK/s contribute to pearl millet defense against the downy mildew pathogen by activating

251 ermal barrier epithelia form a first line of defense against the environment, protecting animals agai

252 the actin-depolymerizing function of ADF3 in defense against the GPA, we show that resistance in adf3

253 okine gamma interferon (IFN-gamma), and host defense against the intracellular pathogens Toxoplasma g

254 mosquitoes shows that a molecule involved in defense against the malaria parasite also plays a role i

255 ay protective and regulatory roles in immune defense against the opportunistic mold Aspergillus fumig

256 ted pathogen detection is important for host defense against the opportunistic pathogen Acinetobacter

257 ial role of long-distance signaling in maize defense against the phloem-feeding insects.

258 indings, we propose a model for soybean root defense against the SDS pathogen.

259 ic wastewater treatment is among our primary defenses against the dissemination of infectious waterbo

260 FICIENT4, which is an important regulator of defenses against the GPA.

261 ry disease is able to promote antiviral host defenses against the influenza virus.

262 CD4(+) T lymphocytes are critical for host defense against this infection, but in the absence of CD

263 the Fv3 infection strategies and the immune defense against this pathogen.

264 eby providing a first line of pharmaceutical defense against this possible scenario.

265 hus essential to develop innovative means of defense against this virus.

266 duced cFLIP was found to be critical for LCL defense against TNFalpha-mediated programmed cell death,

267 ents to investigate the role of BRs in plant defense against Tobacco Mosaic Virus (TMV) in Nicotiana

268 dary metabolites; changes in metabolism; and defense against toxic compounds.

269 matory monocytes (iMO) are critical for host defense against toxoplasmosis and malaria but their role

270 Small RNAs play a crucial role in genome defense against transposable elements and guide Argonaut

271 ired for selective autophagy of Mtb and host defense against tuberculosis infection.

272 e is evidence that IL-17 plays a role in the defense against tuberculosis.

273 evidence for the role of humoral immunity in defense against tuberculosis.

274 egy adopted by BR proteins to solidify their defenses against unfavorable environments and maintain t

275 ional signature and the role of CD14 in host defense against UTI in the bladder.

276 odulation, augmentation of the Cu-based host defense against UTI represents a novel approach to limit

277 nd topically applied DHA potentiate cellular defense against UVB-induced skin inflammation and photoc

278 defense pathway plays a central role in the defense against vacuolar pathogens and describe a mechan

279 pendent effector mechanisms in acquired host defense against venoms.

280 totoxic T lymphocytes are essential for host defense against viral infection and cancer.

281 However, the involvement of TRIM14 in host defense against viral infection and molecular mechanisms

282 ition receptor, functions as a first line of defense against viral infection by sensing double-strand

283 beta-defensin family plays a role in host defense against viral infection, however its role in HCV

284 nduction characteristic of the first line of defense against viral infection.

285 The first line of defense against viral infections is the innate immune re

286 te immune system serves as the first line of defense against viral infections.

287 ons (IFNs) play a central role in the immune defense against viral infections.

288 ic egress and T-cell survival, as well as in defense against viral pathogens.

289 Cytosolic RNA/DNA sensing elicits primary defense against viral pathogens.

290 e important components of intrinsic cellular defenses against viral infection.

291 s (IFN-lambda) function as the first line of defense against virus infection and regulate the develop

292 Type I IFNs are key mediators of immune defense against viruses and bacteria.

293 C-type lectin receptor involved in the host defense against viruses such as HIV and influenza as wel

294 its prokaryotic host with an adaptive immune defense against viruses that have been previously encoun

295 MHC class I is critically involved in defense against viruses, and diversity from polygeny and

296 innate immune response is the first line of defense against viruses, and type I interferon (IFN) is

297 nt antiviral gene program essential for host defense against viruses.

298 erferons (IFNs) constitute the first line of defense against viruses.

299 IFNlambda is important for epidermal defense against viruses.

300 genes that have evolved to provide intrinsic defense against viruses.