ライフサイエンスコーパス: definitively

1 although more work is required to show this definitively.

2 that might potentially answer this question definitively.

3 r AAV transduction remains to be established definitively.

4 whose importance has not yet been determined definitively.

5 assign the putative Na(+) and H(+) transport definitively.

6 achomatis conjunctivitis should be diagnosed definitively.

7 , the study is not powered to address safety definitively.

8 re, stroke, and diabetes mellitus though not definitively.

9 m apoptotic and necrotic cells instantly and definitively.

10 cific binding sites have not been identified definitively.

11 st researchers to approach this problem more definitively.

12 the role of innate immunity for clearing HCV definitively.

13 ld be needed to mechanistically link the two definitively.

14 r linked help, but has not been demonstrated definitively.

15 ling in prostate cancer has not been defined definitively.

16 the role were more likely to manage the call definitively.

17 without a threshold, but has not been shown definitively.

18 To prove definitively a causal role of leptin in the pathogenesis

19 c theories, but one cannot conclude anything definitively about the shape of those theories from any

20 ing consistency, but no mechanism has yet to definitively account for this sex difference.

21 In summary, LIN28B can definitively act as an oncogene in the absence of canoni

22 knockout mouse model (C2KO) designed to more definitively address questions of sAC expression, and we

23 mice will be an essential tool with which to definitively address the biological functions of NDPK-B.

24 prospective studies should be undertaken to definitively address the role of TCD in HCT.

25 A randomized trial is needed to definitively address this question.

26 tumor initiation or maintenance has not been definitively addressed.

27 oritized in a phase II trial are then tested definitively against a control treatment in a randomized

28 he 1990s; the data also suggest (albeit less definitively) an increase in winter CO2 emissions, espec

29 erve as a tool for identifying waste sources definitively, analyzing population diversity, and conduc

30 s was performed on patients who were treated definitively and underwent post-treatment PET imaging pe

31 ed to be combined with additional studies to definitively assess appropriateness for mass respiratory

32 dequately powered trial would be required to definitively assess the efficacy and safety of this appr

33 Prolonged follow-up is warranted to definitively assess their risk of developing second canc

34 pain-2 activities in mouse brain, which more definitively assesses the role of these ubiquitous prote

35 ific environment, it has been challenging to definitively assign adaptive functions to specific mtDNA

36 tion of the newly created chiral centers was definitively assigned for all the corresponding compound

37 3) ambiguous VDPVs (aVDPVs), which cannot be definitively assigned to either of the first 2 categorie

38 Of those, nine were definitively assigned to S. jamesii based on possession

39 Seven of nine disulfide bonds were definitively assigned; the remaining two bonds were assi

40 solated from these koalas, KoRV has not been definitively associated with leukemogenesis.

41 estral in land plants cannot yet be answered definitively based on existing data.

42 , no single change in the gut microbiota has definitively been identified as a risk factor or cause o

43 Hypothermia, while having promise, has not definitively been shown to benefit patients with traumat

44 or MRI, in patients at high risk of HCC, as definitively benign, probably benign, intermediate proba

45 implants, direct comparisons cannot be made definitively between implant types, and future investiga

46 we cannot, with available data, discriminate definitively between the effect of true peer effects and

47 We identified definitively bivalent nucleosomes with concomitant repre

48 on long-term survival can only be confirmed definitively by randomized studies.

49 r all clinically relevant pneumococci can be definitively categorized into distinct serotypes.

50 Research is needed to more definitively characterize the epidemiology of TBI-relate

51 nscript models produced by CLS enabled us to definitively characterize the genomic features of lncRNA

52 pposed to other aspects of song has not been definitively characterized.

53 tion(s) to the regenerated fin have not been definitively characterized.

54 About one-third of the OTUs could not be definitively classified at a similarity level of 80%, su

55 10%), insufficient evidence was available to definitively classify reason for presentation.

56 Abdomens were definitively closed downrange (11%), at Landstuhl Region

57 d trial with long-term outcomes is needed to definitively compare the effectiveness of these 2 revasc

58 hes with multiple human cell sources, we can definitively conclude that CpG methylation is absent in

59 rmation of B. pertussis infection, we cannot definitively conclude that pertussis disease is well con

60 milarity with that of MxiC from Shigella, we definitively confirm CopN as the Chlamydia homolog of th

61 and experimental studies have been unable to definitively confirm or disprove this observation.

62 e and noninvasive hemodynamic assessments to definitively confirm or refute the diagnosis of HFpEF.

63 e IPF remains unclear, limited data exist to definitively connect abnormal imaging findings to IPF, a

64 d cytotoxic mediators and have been shown to definitively contribute to asthma.

65 This mutant definitively correlates the 2-5 bp deletions observed in

66 promyelocytic leukemia (APL) patients can be definitively cured by the combination of two targeted th

67 Oral administration of azithromycin definitively decreases the diversity of the gut microbio

68 atients without JAK2 mutations, has not been definitively delineated.

69 We also could not definitively demonstrate between-group differences in me

70 The results definitively demonstrate concurrent redox reactions of b

71 We thus definitively demonstrate stereopsis in mantises and also

72 provide genetic and biochemical evidence to definitively demonstrate that a C-terminal loop structur

73 These studies definitively demonstrate the first known function of C3

74 The authors could not definitively demonstrate whether the addition of 2 years

75 Conclusion: The authors could not definitively demonstrate whether the addition of 2 years

76 We definitively demonstrate, using genetic mouse models, th

77 tolerance following transplantation have not definitively demonstrated a role for regulatory cells in

78 tence and neuropathogenesis but has not been definitively demonstrated in an animal model of HIV-indu

79 ity produced non-enzymatically have not been definitively demonstrated to mediate any known disease p

80 to long-term antibody titers--have not been definitively demonstrated.

81 This study definitively demonstrates that autoimmune demyelinating

82 Mutational analysis definitively demonstrates that TbPRMT1(ENZ) is the cofac

83 This study definitively demonstrates with Raman and UV-vis spectros

84 Still, definitively demonstrating the human benefits of isolate

85 us is a murine roseolovirus (MRV), the first definitively described rodent roseolovirus, to our knowl

86 Only a rostral forelimb area (RFA) has been definitively described, besides few reports of a rostral

87 at over 100 carbon-bearing species have been definitively detected in the interstellar medium via the

88 These findings require replication to definitively determine clinical utility of this treatmen

89 rge clinical trial data are required to more definitively determine CTO revascularization guidelines.

90 Longer-term studies are needed to definitively determine the effect of bougie size on weig

91 full phylogenetic tree would be required to definitively determine the effect of genetic evolution o

92 diagnosed in the 1970s makes it difficult to definitively determine the effect of risk factors on lat

93 ic iPSC-derived hepatocytes could be used to definitively determine the functional contribution of al

94 and a randomized clinical trial is needed to definitively determine the impact of penicillin prophyla

95 ement, additional study is warranted to more definitively determine the optimal methods to detect pre

96 controlled, randomized studies are needed to definitively determine their role in the treatment of my

97 cance of these findings will need to be more definitively determined in future Phase 3 studies.

98 around the macrocycle in each porphyrin was definitively determined using a combination of 1D ((1)H

99 f the 4 dengue virus serotypes remains to be definitively determined.

100 s controlling its biosynthesis have not been definitively determined.

101 cleotide affects polymerization remain to be definitively determined.

102 ns of the glutamatergic input have yet to be definitively determined.

103 nfluenza A infections in humans has not been definitively determined.

104 egative for AQP4-Abs and may be difficult to definitively diagnose.

105 Of these 8 patients, 2 were definitively diagnosed as having TINU syndrome (confirme

106 e disorder affecting movement and cognition, definitively diagnosed only at autopsy.

107 oward diagnosis of type 1; type 2 AIP can be definitively diagnosed only on pancreatic histology.

108 evaluations, while CTE currently only can be definitively diagnosed postmortem.

109 are 4 times after illness onset before being definitively diagnosed with trichinellosis.

110 In summary, because no single test definitively diagnoses IgG4-related systemic disease, we

111 but no finding or combination of findings is definitively diagnostic in all patients, and diagnostic

112 set of virulence factors that can be used to definitively differentiate these pathotypes.

113 clinically active targeted therapeutics can definitively discriminate driver from passenger lesions

114 well understood because no method exists to definitively distinguish regenerated from preexisting my

115 Because isotopic patterns cannot definitively distinguish these alternatives, we pursued

116 etry, we show that these two populations are definitively distinguishable by phenotype in retina.

117 of the 1953 operation could not be assessed definitively during H.M.'s life.

118 nctional epicardial substrates, which may be definitively eliminated by radiofrequency ablation, rema

119 ed by the amount of information available to definitively elucidate the molecular formula of a molecu

120 gh the pathological mechanisms have not been definitively elucidated, evidence suggests a key role fo

121 rmation of a case of Ebola virus disease, we definitively enumerated on a list a ring (cluster) of al

122 y useful human cell lines, we used TALENs to definitively eradicate LEDGF/p75 by deleting either all

123 t these properties have not been established definitively, especially in bilayer membranes with physi

124 Efforts to definitively establish a similar stem cell hierarchy wit

125 Thus, our findings definitively establish an essential role of TRADD in DR3

126 demonstrated that Titmus stereoacuity cannot definitively establish normal VA, and therefore can sugg

127 These data definitively establish that complete structural integrit

128 ternal Cdx2 using a Cre/lox strategy, and we definitively establish that maternal Cdx2 is not essenti

129 or a large, multicenter, randomized trial to definitively establish the first-line medical therapy fo

130 To definitively establish the functional role of PERK in ad

131 However, further studies will be required to definitively establish the identity of the causative gen

132 Further studies are needed to definitively establish the mechanisms by which G6PD defi

133 provided sufficient clinical information to definitively establish the presence or absence of glauco

134 ess analyses using observational data cannot definitively establish the superiority of one technique

135 ed, controlled trials are urgently needed to definitively establish their potential for smoking cessa

136 comes of chemotherapy-treated adults are not definitively established and should be evaluated.

137 link between RABV and human disease has been definitively established and the extent to which RABV ut

138 is, thermotaxis, and rheotaxis have not been definitively established in mammals.

139 orbiting such a pair of normal stars was not definitively established until the discovery of the plan

140 he reducing equivalents in vivo has not been definitively established, but a cyanobacterial [2Fe-2S]

141 The pathogenicity of norovirus is definitively established.

142 failure in normal sinus rhythm has not been definitively established.

143 2 cases (5.3%), linkage status could not be definitively established.

144 n and progression to cancer has not yet been definitively established.

145 the central nervous system have rarely been definitively established.

146 trioid endometrial cancer (EEC) has not been definitively established.

147 Our in vivo model also definitively establishes TCT as the long-distance elicit

148 This work definitively establishes the differential effector funct

149 remained residual CD28-dependent responses, definitively establishing that additional motifs can par

150 editing is potentially an important tool for definitively establishing the functional roles of indivi

151 cells at levels similar to those of V exons, definitively establishing the V exon location as "privil

152 To definitively evaluate the possibility that miRNAs could

153 individual blood cell lineages has not been definitively evaluated.

154 d N-terminal antibodies, allowing us to more definitively examine the role of Shank3 in synaptic func

155 identified, and further study is required to definitively exclude potential benefit or potential harm

156 dard, and in some cases malignancy cannot be definitively excluded on the basis of cardiac MRI images

157 To definitively explore the potential for clinical efficacy

158 rotein characterization, showing that AI-ETD definitively extends the m/z range over which ETD can be

159 Half of readmissions were definitively for new infections, whereas an additional 3

160 durable therapy for the treatment of BPH has definitively found its place as one of the alternatives

161 with which to identify and distinguish them definitively from other types of glia.

162 e randomized controlled trials are needed to definitively guide the clinical use of probiotics in out

163 avior in soils, enantiopure (-)-beflubutamid definitively has the potential to substitute for the rac

164 probability of being HCC, probably HCC, and definitively HCC (corresponding to LI-RADS categories 1-

165 Doppler ultrasound definitively helps to diagnose the tumor thrombus, the e

166 etic makeup of Europeans now shows even more definitively how false those notions are.

167 The definitively identified ("canonical") residues that are

168 ociative process once the behavioral goal is definitively identified by first trial performance feedb

169 1,610 predicted Bm gene products, 7,103 were definitively identified from adult male, adult female, b

170 ines in a long-term snow-addition experiment definitively identified increasing late-summer dryness a

171 to arginine and lysine variants of PAI-1 and definitively identified the binding site as composed of

172 ent signaling, although no receptor has been definitively identified yet.

173 ne-spanning OMPs of B. burgdorferi have been definitively identified, and none are well characterized

174 an antigen or autoantigen that has yet to be definitively identified, reducing the activity of intrin

175 n(s) of theca progenitor cells have not been definitively identified.

176 y (OPAT) at hospital discharge have not been definitively identified.

177 (s) responsible for this event have not been definitively identified.

178 restricted until causal factors can be more definitively identified.

179 dentified while one metabolite, taurine, was definitively identified.

180 tality for which causal agents have not been definitively identified.

181 The patient's infection source was not definitively identified.

182 at is, the signaling mechanism-have not been definitively identified.

183 tified, but direct Fru targets have not been definitively identified.

184 Ultimately, we were able to definitively identify 3 proteins as putatively metastabl

185 hese instruments have never been utilized to definitively identify aerosolized microbes in ambient se

186 othelial nuclei and membranes we are able to definitively identify and study the morphology and behav

187 that very large samples will be required to definitively identify individual rare variants or genes

188 e interface (BMI) experiments where we could definitively identify neural firing patterns as output-n

189 To definitively identify regenerated myelin, we used a tran

190 Finally, although available data do not definitively identify the cell(s) of origin, we offer po

191 To definitively identify the channel, we use whole-mitoplas

192 h patients, but liver biopsy is necessary to definitively identify those at risk for liver disease pr

193 elves may bring their own data to the table, definitively identifying clinically significant genomic

194 and theoretical spectra could not establish definitively if a single structure or a mixture of confo

195 ed for appropriately designed studies before definitively implementing strategies.

196 estions remain even after a genomic locus is definitively implicated, including the nature of the cau

197 y a limited number of genetic loci have been definitively implicated.

198 spid regurgitation in left heart disease can definitively improve clinical outcomes should be address

199 (2) If so, do these definitively improve outcomes?

200 xic chemotherapy such as ifosfamide have not definitively improved the survival of patients with oste

201 e, but these questions must be assessed more definitively in prospective cohorts.

202 reclinical animal studies of these nutrients definitively influenced the design and interpretation of

203 ibility of unmeasured confounding, we cannot definitively interpret these results as causal.

204 It is not yet definitively known whether dynamic features of head circ

205 he primary reservoir sites in humans are not definitively known, but analysis of murine models has id

206 ory cytokines control ADAMTS activity is not definitively known.

207 ness of therapy in this patient group is not definitively known.

208 Here, we definitively link cytotoxicity associated with SOD1 aggr

209 odels has prevented studies which would more definitively link these viral infections to disease.

210 However, no longitudinal research has definitively linked these behavioral changes to underlyi

211 of pancreatic ductal adenocarcinoma (PDA) is definitively linked to activating mutations in the KRAS

212 ense variants in APOL1 (G1 and G2) have been definitively linked to CKD in black Americans.

213 by treatment with broad-spectrum antibiotics definitively links the role of the microbiota and microb

214 , no lysine acetyltransferase (KAT) has been definitively localized to this organelle to date.

215 Although we cannot definitively locate all of the atoms inside the nanopart

216 ed, we need a precise genetic null mutant to definitively map its amorphic phenotypes.

217 ents between liberated peptides, we now have definitively mapped 5 disulfide bonds in IGFBP-5.

218 ic compounds were detected, but they are not definitively martian in origin.

219 n western Eurasia, Tam Pa Ling establishes a definitively modern population in Southeast Asia at ~50

220 tency shorter than 1.2 ms were classified as definitively monosynaptic; these were seen only after st

221 While AMA1 is definitively not an essential protein for tachyzoite ent

222 erature magnetic field effects have not been definitively observed in either single-walled carbon nan

223 ime, a unique convective mode not previously definitively observed in the Solar System.

224 trate that driver mutations occurring in MDS definitively occur in cells with a stem cell phenotype.

225 urce for the chlorinated hydrocarbons is not definitively of martian origin.

226 ENT Neurodegenerative diseases are diagnosed definitively only in postmortem brains by the presence o

227 The net effect on climate is definitively positive forcing as coemitted organic carbo

228 MRI, or gadoxetate-enhanced MRI could not be definitively preferred for HCC diagnosis in patients wit

229 The authors definitively prove that the initiation of cell polarizat

230 tamin B12 is the only nutritional deficiency definitively proved to cause optic neuropathy and loss o

231 sistance of these interventions has not been definitively proved.

232 Cytokine inhibitors have definitively proven a critical role for tumour necrosis

233 Final structures of five scaffolds have been definitively proven by X-ray crystallography.

234 CD implantation, its usefulness has not been definitively proven.

235 east a small net benefit, but stops short of definitively recommending that this cohort be screened.

236 Schmitz and Motani claimed to definitively reconstruct activity patterns of Mesozoic a

237 rganic matter (DOM) obstructs our ability to definitively recover source compounds from within DOM, a

238 Phylogenetic analysis definitively recovers the species as an abelisauroid the

239 on mortality in trials of interventions that definitively reduced CKD endpoints.

240 d the end of the Cretaceous, but none can be definitively referred to the Neornithes.

241 To more definitively resolve this question, we generated acute m

242 esis of the anchoring elements have not been definitively resolved.

243 f GJ 1214b at near-infrared wavelengths that definitively resolves this ambiguity.

244 However, no gag and gp41-CD mutations definitively responsible for reduced PI susceptibility h

245 These studies definitively rule out a role for all conserved consensus

246 The results obtained definitively rule out a simple bimolecular nucleation me

247 ure and its immunohistochemical features can definitively separate canaliculops from conjunctival cys

248 Implicitly, data also definitively settle a currently unsolved issue on the ca

249 Our data definitively show that Arg143 serves as a kinetically si

250 The results also definitively show that distraction is detrimental to dri

251 Here we definitively show that substantial quantities of trypano

252 Affymetrix canine microarray, we are able to definitively show that there are significant differences

253 In addition, we definitively show the atomic-scale distribution of phosp

254 randomised, controlled trials are needed to definitively show the magnitude of benefit, if any, of t

255 y a better choice than effective absorbance) definitively show there are at least three distinct mole

256 stent with, and extend, previous findings by definitively showing a significant and large reduction i

257 NT FINDINGS: Clinical trials in CKD have not definitively shown that setting a BP target that is lowe

258 , post-transplantation survival has not been definitively shown to be less than average in patients w

259 ndom walk, however, no detailed analysis has definitively shown whether T cell movement is consistent

260 Our present study definitively shows that RNAi is an important modulator o

261 -IV has been reinforced by SHARP, which also definitively shows that there are no special safety conc

262 rd (239 [35%] of 707) of open fractures were definitively stabilised later than 24 h.

263 se Ki67 and PEPI triage approaches are being definitively studied in the ALTERNATE trial.

264 As researchers plan clinical trials to more definitively study whether statins indeed protect agains

265 ndomized controlled clinical trials exist to definitively support the efficacy of surveillance progra

266 However, this hypothesis has not yet been definitively supported in vivo.

267 ing transport where high-field MR saturation definitively supports spin polarization instead of a mor

268 AMG900 is a promising opportunity to definitively test the clinical benefit of dual Aurora ki

269 eved with our intervention, are indicated to definitively test this potentially safe and inexpensive

270 s for the need for large phase III trials to definitively test this question.

271 This trial was designed to definitively test whether calcium/magnesium decreases ox

272 comparative effectiveness research should be definitively tested by randomized, controlled trials.

273 confined to the tips of the thalli and show definitively that a lack of structural colour elsewhere

274 cebo-controlled randomised trials have shown definitively that almost all of the symptomatic adverse

275 Our data demonstrate definitively that both H1R and H2R participate in the im

276 letion virus that lacks the H5 gene and show definitively that genome synthesis does not occur in the

277 Further, this work demonstrates definitively that mouse collecting lymphatic vessels exh

278 Here we demonstrate definitively that neurons from native neural networks wi

279 double subunit knock-out mice to demonstrate definitively that TASK channels account for motoneuronal

280 -affinity Rem2/Cavbeta4 interaction and show definitively that the interaction is required for Cav2.1

281 lity mechanically cleaved HOPG, demonstrates definitively that the pristine basal surface supports fa

282 lmost exclusively at CpG islands and support definitively that these tumors were appropriately named.

283 basidiomycete fungi growing in agar, showing definitively that these widespread heterotrophic fungi c

284 Our results show definitively that Type I X-linked miRNA genes are subjec

285 Identifying definitively the controls over the rivermouth effect on

286 tures and activation of pathways to localize definitively the essential memory trace.

287 are an alternative source, but to ascertain definitively the identity and fidelity of cell types gen

288 Although too early to tell definitively, the observed die-out of OPV2-related virus

289 though fiber supplements have not been shown definitively to benefit patients with IBD, soluble fiber

290 n its early stages, and its development will definitively transform the fundamental understanding of

291 The patients definitively treated with in vitro active cefepime (case

292 At pH <7.4, the spectra are definitively type I, whereas at pH >/=7.4 the spectra ha

293 ll genomic approaches are uniquely placed to definitively unravel complex clonal structures and tissu

294 To address these issues definitively, we developed RgIA4, a peptide that exhibit

295 nts underlying IAI have yet to be identified definitively; we argue that these molecules are surface-

296 breathing trial, 86 were extubated, 57 were definitively weaned (group 1), and 29 suffered from post

297 er group makes it more difficult to conclude definitively whether perchlorate reduction does or does

298 ion of clinical trials designed to determine definitively whether screening for and treatment of M. g

299 intervention on neural activity to determine definitively whether specific neural activity features a

300 ed 195 patients with stage III NSCLC treated definitively with radiation therapy between January 2008