ライフサイエンスコーパス: degradation product

1 tereomers of palmyrolide A aldehyde, a known degradation product.

2 carbon into microbial biomass are treated as degradation products.

3 uantification of several CWA types and their degradation products.

4 ely eliminated in relation to other volatile degradation products.

5 etrahydro-beta-carbolines gave oxidative and degradation products.

6 cle Z-discs and accumulation of myofibrillar degradation products.

7 lent of the unique FTACP and the increase of degradation products.

8 lso identified pyruvate and ammonia as other degradation products.

9 avoiding the formation of highly chlorinated degradation products.

10 aminants such as plasticizers, and initiator degradation products.

11 press the formation of Maillard and Strecker degradation products.

12 impeded, suggesting involvement of APP/APLP2 degradation products.

13 or formation curves of at least 13 different degradation products.

14 for detecting these explosives and explosive degradation products.

15 abolites, as well as some microbial-specific degradation products.

16 status and compartment, and releases matrix degradation products.

17 d that HARE senses a narrow size range of HA degradation products.

18 bstrates, and evaluating the toxicity of the degradation products.

19 y the nanoparticle but also all its possible degradation products.

20 MMP-driven immunopathology generates matrix degradation products.

21 because of its safety profile with non-toxic degradation products.

22 cting the budgets of these species and their degradation products.

23 and DNA, has not been implemented for lignin degradation products.

24 m was however evident for the removal of the degradation products.

25 wide range of hydrocarbon compounds or their degradation products.

26 n a time-dependent manner, yielding specific degradation products.

27 ptidases and mass spectrometry to define the degradation products.

28 on/proliferation therein, in response to ECM degradation products.

29 ctrophoresis to remove undesired side and/or degradation products.

30 the characterization of human growth hormone degradation products.

31 n, but no such effects were observed for the degradation products.

32 ve components such as anthocyanins and their degradation products.

33 Raman measurements confirm the formation of degradation products.

34 balance could be closed by including several degradation products.

35 lites are therefore suspects for anthocyanin degradation products.

36 nd directly cleaved C3b and iC3b to generate degradation products.

37 rrent- and historic-use pesticides and their degradation products.

38 serve as receptors for enterobactin and its degradation product 2,3-dihydroxybenzoic acid.

39 ethod for the hydrolysis of amitraz, and its degradation products 2,4-dimethylphenyl-N'-methylformami

40 nium-based contrast materials, 2. hemoglobin degradation products 3. melanin, 4. mucous- or protein-c

41 ecent SCs (UR-144, XLR-11, and their thermal degradation products; AB-CHMINACA and ADB-CHMINACA) and

42 orbate reductase showed a slight decrease in degradation product accumulation.

43 ments revealed an important role for the C3a degradation product acylation-stimulating protein (ASP)

44 avage resulting in largely non-amyloidogenic degradation products, adenoviral overexpression of MMP-9

45 rived aldehydes, and the intermediate lysine degradation product, alpha-aminoadipic semialdehyde.

46 ed by earlier studies that employed only DNA degradation product analysis as an end point.

47 , we used a library representative of lignin degradation products and a thermal stability screen to d

48 genic necrotic cells, eliminated proteasomal degradation products and blocked Ag cross-presentation.

49 chemical activity of the electrolyte and its degradation products and can create differences in trans

50 found to be well resolved in the presence of degradation products and excipients.

51 des the crosslinked fibrin to release fibrin degradation products and expose the D-dimer antigen.

52 lizes aromatic compounds derived from lignin degradation products and has the potential for bioremedi

53 nA-null platelets contain multiple GPIbalpha degradation products and have increased expression of th

54 nd this technique to a complex mixture of VX degradation products and identify all the main phosphoru

55 ry diseases given its neutral, biocompatible degradation products and its ability to deliver a wide r

56 del solution (pH 5) to delineate their major degradation products and mechanism(s).

57 des the identification of previously unknown degradation products and minor components.

58 A detailed consideration of possible degradation products and pathways would have been beyond

59 hers, is of great concern from a dioxin-like degradation products and toxicity perspective.

60 3-BRS comprising C-reactive protein, fibrin degradation product, and heat shock protein-70 improved

61 for risk factors, C-reactive protein, fibrin degradation product, and heat shock protein-70.

62 erdin (BV) as a chromophore, which is a heme degradation product, and therefore they are straightforw

63 matory response to the terpolymers and their degradation products, and (ii) normal progression of hea

64 els of biomarkers C-reactive protein, fibrin degradation products, and heat shock protein-70 represen

65 the organosiloxanes, low volatility of their degradation products, and reactivity of those compounds

66 ts, angiotensin-(1-7) and neprilysin-derived degradation products angiotensin-(1-4), angiotensin-(5-7

67 lood coagulation markers (fibrinogen, fibrin-degradation products, APTT), and preserved the endotheli

68 HPLC and electronic spectra, the major heme degradation products are 5-oxo-delta-bilirubin and 15-ox

69 This study reveals that netrin-1 degradation products are capable of modulating vascular

70 t community member are only possible because degradation products are consumed by the second communit

71 The results indicate that the identified degradation products are formed from side-reactions and/

72 f the plasma air purifier to determine which degradation products are formed.

73 tion assays demonstrate that PKHEs and their degradation products are highly biocompatible.

74 The levels of filaggrin and its degradation products are influenced not only by the fila

75 Kynurenine pathway metabolites and ascorbate degradation products are present in human lenses.

76 g effects of ellagic acid and its intestinal degradation products are well-known.

77 ilins, tetrapyrrolic, bilin-type chlorophyll degradation products, are abundant chlorophyll catabolit

78 Volatile degradation products arising from carotenoids and amino

79 noids, fatty acid derivatives and carotenoid degradation products as volatiles clearly changing durin

80 inguish between first- and second-generation degradation products, as well as impurities resulting fr

81 6, and 8 hours, and blood fibrin/fibrinogen degradation products at 4 hours after NK administration

82 Chalcones were identified as the major heat degradation products at pH 3-7.

83 ntigen (HLA) proteins, which present protein degradation products at the cell surface to circulating

84 To facilitate the analysis of degradation products, autoxidation of the three methine

85 It is therefore recommended that these degradation products be included in programs monitoring

86 in acid extracts, coming from materials and degradation products belonging to built heritage (mortar

87 ntification of 3-deoxythreosone as the major degradation product bound to human lens proteins provide

88 intracellular generation of the (R,S)-AdoMet degradation product but for utilizing environmental sour

89 Early degradation products (but not the final bicyclopentadion

90 26 nucleotide small RNAs that are not random degradation products, but are rather specifically cleave

91 It was isolated along with an acid-catalyzed degradation product by bioassay-guided fractionation.

92 raphy (RP-HPLC) and tracking the presence of degradation products by MALDI-MS.

93 (300 ng/ml) and monitored the appearance of degradation products by mass spectrometry.

94 l undesired products, including truncations, degradation products, byproducts, and differentially mod

95 ch as lens, brain and adrenal gland, and its degradation products can inflict substantial protein dam

96 imicked by exogenous application of the heme degradation product CO.

97 of chlorobenzene via benzene to the nontoxic degradation products, CO2 and CH4.

98 ls of EpFAs in the plasma, and a decrease in degradation products coincided with the dihydroxy fatty

99 establish nonselective adsorption of glucose degradation products containing carboxylic acids on both

100 The presence of hydrogel degradation products containing the fluorescent label in

101 This final inactive degradation product could be reactivated in vitro by inc

102 Partial degradation products could exit the complex through tran

103 rmined the levels of vitamin C oxidation and degradation products dehydroascorbic acid, 2,3-diketogul

104 ne were the most abundant antidepressant and degradation product detected in the biosolid samples.

105 Octylisothiazolinone degradation products did not accumulate over time sugges

106 atoes were kept at 20 degrees C, while lipid degradation products did not vary.

107 hoxyglucobrassicin, but the formation of the degradation products dihydroascorbigen and dihydro-4-met

108 (K(OA)) for those compounds and their common degradation product, dimethylsilanediol, are critical fo

109 eased ABA levels and decreased levels of ABA degradation products diphaseic acid and phaseic acid.

110 Results suggest that HT and its degradation product DOPAC could have a relevant role in

111 Da) in bovine M. longissimus dorsi and their degradation products during post mortem ageing were inve

112 t only binds and clears extracellular matrix degradation products (e.g. released normally or during i

113 Supporting growth experiments, PNP degradation products entered central metabolic pathways

114 sensitivity C-reactive protein (CRP), fibrin degradation products (FDP), and heat shock protein 70 (H

115 and groundwater wells showed leaching of the degradation products fluazifop-P (FP) and 2-hydroxy-5-tr

116 proach may be useful to predict the fates of degradation products for a wide range of complicated org

117 Moreover, we observed distinct proteolytic degradation products for hcTnT and mcTnT.

118 H solutions containing low levels of glucose degradation products for peritoneal dialysis compared wi

119 Analysis of the limited degradation product formed by meprin A indicated that th

120 Glyoxylic acid is a tartaric acid degradation product formed in model wine solutions conta

121 e study deals with the identification of the degradation products formed by simulated sunlight photoi

122 extraction of the target antidepressants and degradation products from biosolids, or more specificall

123 of fermentation on glucosinolates and their degradation products from fresh raw cabbage, throughout

124 leavage of the ester linkage, and subsequent degradation products from FTOH for 80 d.

125 ikely due to the accumulation of atmospheric degradation products from gas-phase reactions of volatil

126 This work gives new insights into the degradation products from metal devices as well as guida

127 des to drugs including steroids, and include degradation products from natural sources.

128 The degradation products from the pesticides resulting from

129 emonstrated that 21-22 nucleotide (nt) siRNA degradation products from the RNAi of TE mRNAs are direc

130 e found between sugars, ascorbic acid, their degradation products (furfural and HMF) and total colour

131 ss spectrometry analysis identified distinct degradation products generated from Abeta digestion by M

132 D-dimer, a fibrin degradation product, generated following activation of t

133 that the three uptake systems for the chitin degradation products GlcNAc, (GlcNAc)2 and (GlcN)2 , pla

134 esulting monosaccharide-and-linkage-specific degradation products ("glycan nodes") that directly repr

135 vel metabolite roquefortine L, including its degradation products, harboring remarkable chemical stru

136 pair of homologous series of polyfluorinated degradation products have been identified, both having s

137 METHODS AND C-reactive protein, fibrin degradation product, heat shock protein-70, and suPAR we

138 tified in the raw wastewater and (iv) the 55 degradation products identified during wastewater treatm

139 s confirmed in this study as the actual DCAN degradation product in chlorinated drinking waters.

140 amelogenin, while the predominant amelogenin degradation product in developing enamel (e.g., P148) pr

141 e contents of glucosinolates (GLS) and their degradation products in a boiled white cabbage.

142 describe an analytical tool to characterize degradation products in a highly diluted medium.

143 by in vivo administration of chemotactic ECM degradation products in a mammalian model of digit amput

144 To identify the dye degradation products in a very complex scenario, a metho

145 The analysis of impurities and degradation products in API and formulated drug product

146 lated peptides or proteins and their related degradation products in biological matrixes.

147 ivo pathology by searching for corresponding degradation products in human aortic tissue with differe

148 Our study conducted targeted screening for degradation products in polyglucose (icodextrin)-contain

149 phates (PAPs) and their intermediate and end degradation products in popcorn bags.

150 ns, to avoid the unwanted release of plastic degradation products in receiving environments.

151 y evaluated the aromatic compounds and their degradation products in samples influenced by the petrol

152 ed for parent compounds as well as terbutryn degradation products in soils below biocide treated faca

153 chlorination of CPs and are expected thermal degradation products in some applications of CPs, for ex

154 enyl ether (BDE-209), that formed photolytic degradation products in tetrahydrofuran (THF)/hexane sol

155 t the need to consider likely impurities and degradation products in the assessment of persistent, bi

156 gnificant increases in the alpha-II spectrin degradation products in the frontal cortex and cerebellu

157 s well, due to the participation of some RNA degradation products in the RNA recombination process.

158 n study that analyzed anthocyanins and their degradation products in the urine, plasma, and ileal eff

159 t detection of the corresponding proteolytic degradation products in urine provides a noninvasive dia

160 minomethyl phosphonic acid, one of its major degradation products) in surface water.

161 ch on 90 pesticide residues, including their degradation products, in three commodities (tomato, pepp

162 s the possible release of amine solvents and degradation products into the atmosphere, warranting eva

163 TAP shuttles proteasomal degradation products into the lumen of the endoplasmic r

164 n from urea and ammonia, which are uric acid degradation products, into glutamate, using urease and g

165 linium - based contrast agents, 2.hemoglobin degradation products (intra- and extra-cellular methemog

166 nce and especially the formation and fate of degradation products is rare.

167 In this study, both degradation products leached to drainage and groundwater

168 ermining these properties for cVMS and their degradation products mainly due to the extremely low wat

169 air: 231.58 and 245.16) and build-up of its degradation products, mainly inosine (control: 13.25; ur

170 )CO2 into starch and of levels of the starch degradation product maltose showed that substantial star

171 n vitro evidence also indicates that elastin degradation products may promote osteogenesis.

172 ion in tuberculosis but the resulting matrix degradation products (MDPs) have not been studied.

173 in the chemical structures proposed for the degradation products might suggest potential hazards to

174 The SI TeDB-DiPhOBz and BDE-209 powder degradation product mixture also significantly induced C

175 A lignin degradation product mixture was analyzed using this meth

176 These resulting degradation product mixtures were administered to chicke

177 a dramatic increase in urinary nitric oxide degradation products nitrite/nitrate.

178 Pollutants such as pesticides and their degradation products occur ubiquitously in natural aquat

179 DELSEVL EKPNDQAE PKEVTEEVSSKDAAE, which is a degradation product of chromogranin A.

180 specimens from 87 patients positive for the degradation product of complement component 4 (C4d) and

181 th was observed, during which butyryl-CoA, a degradation product of ethylmalonyl-CoA, accumulated, su

182 n binding to fragment X, a clottable plasmin degradation product of fibrinogen.

183 Methyl isothiocyanate (92.06%), a degradation product of glucosinolate glucocapparin, was

184 DOPAC was detected as the major degradation product of HT under simulated physiological

185 d malondialdehyde (MDA), a reactive aldehyde degradation product of polyunsaturated lipids produced f

186 A degradation product of riboflavin may be contributing to

187 rooctane sulfonamido acetate (an anticipated degradation product of SAmPAP diester).

188 Sesamol, the phenolic degradation product of sesamolin, although recognised fo

189 ive lipid sphingosine 1-phosphate (S1P) is a degradation product of sphingolipids that are particular

190 measurements of agalA activity and lyso-Gb3 (degradation product of the accumulating Gb3).

191 bis(p-chlorophenyl)-2,2-dichloroethene), the degradation product of the ubiquitous global contaminant

192 The sole atmospheric degradation products of (CF3)2CFCN appear to be NO, COF2

193 priRNAs are degradation products of abundant transcripts, which bind

194 The thermal degradation products of ACs were identified and quantifi

195 d beta-2 microglobulin but contained several degradation products of alpha-1 antitrypsin.

196 characterized by synaptic changes induced by degradation products of amyloid precursor protein (APP).

197 Degradation products of biliverdin were subsequently ann

198 ected by beverage composition and allows the degradation products of carminic acid dye to be identifi

199 ently, Kunne et al. (2016) demonstrated that degradation products of Cas3 obtained during CRISPR inte

200 mass tandem mass spectrometry, the resulting degradation products of chloramphenicol were identified

201 ose triggered by crystalline particulates or degradation products of extracellular matrix.

202 required to identify main cleavage sites and degradation products of GalNAc conjugated and unconjugat

203 l resolution needed to detect impurities and degradation products of interest.

204 studies show that these RNAs are not merely degradation products of longer transcripts but could ind

205 Degradation products of parathion formed by irradiation

206 For the first time, specific degradation products of polyglucose, namely, 4-deoxygluc

207 econd dimension was developed to analyze the degradation products of polysorbate 20.

208 Degradation products of RB221 were identified using GC-M

209 These degradation products of SI-TeDB-DiPhOBz and SI-BDE-209 i

210 bably coming from impurities, byproducts, or degradation products of TBBPA and TBBPA derivatives.

211 In the present study, we found that degradation products of the dye were more potent agents

212 Synechococcus DOM, which may originate from degradation products of the fluorescent phycobilin pigme

213 te ions that themselves are considered to be degradation products of the resin and/or oil in the varn

214 The degradation products of the targeted mRNA, however, are

215 These fragments are thought to represent degradation products of their precursors.

216 ethyl ether is identified as the electrolyte degradation product on the cathode surface by the high m

217 These degradation products or impurities are possibly of envir

218 ly main flame retardants but also of related degradation products or impurities has gained attention

219 foot and either treated with chemotactic ECM degradation products or left untreated.

220 enheimer complexes which did not progress to degradation products over many hours.

221 Vitamin C and its degradation products participate in chemical modificatio

222 presence of intraplaque hemorrhage and heme degradation products, particularly bilirubin by using ou

223 ha, beta, and gamma diastereomers), and HBCD degradation products: pentabromocyclododecanes (PBCDs) a

224 Metabolites were identified as degradation products, phenolic, hippuric, phenylacetic,

225 intestine and modulated the formation of the degradation product phloroglucinol aldehyde (PGAL) in hu

226 on rule were performed, and levels of fibrin degradation products (plasma D-dimers) were assessed bef

227 e showed that erythrulose, a major ascorbate degradation product, reacts spontaneously with 3-hydroxy

228 proteasome; it removes tripeptides from the degradation products released by the proteasome.

229 (terbutryn) and seven (octylisothiazolinone) degradation products, respectively.

230 We describe the characterization of degradation products responsible for color change in nea

231 The accumulation of degradation products results in coupled phenomena of lum

232 Analysis of the degradation products revealed that each substrate was cl

233 Edman degradation analysis of collagen fiber degradation products revealed those initial cleavage sit

234 days after amputation, mice treated with ECM degradation products showed an accumulation of heterogen

235 9 cleaved human AMPKalpha ex vivo, producing degradation products similar in size to those detected f

236 the TBSV RNA in vitro, resulting in TBSV RNA degradation products similar in size to those observed i

237 me points via ICP-MS and identified possible degradation products such as 2,4,6-tribromophenol throug

238 is is further complicated in the presence of degradation products such as chlorinated alkenes (CP-ene

239 ensive, multistep monomer syntheses, and the degradation products such as quinone methides or phthala

240 rosclerosis through specific fatty acids and degradation products such as trimethylamine N-oxide.

241 ategies to minimize emissions of solvent and degradation products, such as ammonia, aldehydes, nitros

242 Yet this is crucial as solvent degradation products, such as organic acids, can increas

243 teration in the distribution of cellohexaose degradation products, suggesting that Trp162 plays a dir

244 ), hexabromocyclododecanes (HBCDs), the HBCD degradation products tetrabromocyclododecenes (TBCDs), a

245 capability to detect trace amounts of a CWA degradation product that is estimated to be less volatil

246 D-dimer is a soluble fibrin degradation product that results from ordered breakdown

247 ad shorter forms of miRNAs that appear to be degradation products that arose during the preparatory s

248 found leaching of intact BisGMA and several degradation products that contained the bisphenol A moie

249 of degradation and the production of partial degradation products that include the resistant domain.

250 veloped an HPLC separation method for lignin degradation products that is amenable to negative-ion-mo

251 ils gave rise to the production of two major degradation products that sorbed to a small extent.

252 e tracking of organofluorine drugs and their degradation products, there is a clear need for sensitiv

253 A method for detecting mustard gas degradation products thiodiglycol (TDG) and thiodiglycol

254 e relied on indirect measurement of presumed degradation products to evaluate the environmental fate

255 portant to know the exact composition of the degradation products to improve biocompatibility of PD f

256 respect to how to avoid cytotoxicity of the degradation products to neuronal cells.

257 responsible in binding of the parent dye and degradation products to the enzyme.

258 The present study revealed the nature of degradation products using [(14) C]ascorbate labelling i

259 e-binding proteins that interact with lignin degradation products using high throughput genomic and b

260 dative metabolites, and structurally related degradation products (vanillin, ferulic acid, and ferulo

261 ; the elucidation of expected and unexpected degradation products was achieved in subnanomolar range.

262 A faster increase in ATP degradation products was detected during storage of gona

263 The identity of released degradation products was investigated, and a possible me

264 ta, and fractions of metabolite formation of degradation products was statistically quantified via pr

265 ion of chloroform (CF), the only chlorinated degradation product, was also detected (yields <6.3%).

266 By analyzing purified peptidoglycan (PG) degradation products, we showed that Lc-Lys is an N-acet

267 I-CXCL12 uptake and release of (125)I-CXCL12 degradation products were accelerated with receptors bea

268 on of beads was determined by HPLC-MS-MS and degradation products were also analysed after storage; b

269 mechanism, reaction intermediates, and final degradation products were analyzed by UV/vis, NMR, GC-MS

270 The structures of the degradation products were derived from accurate molecula

271 e terpenes, free fatty acids and carotenoids degradation products were detected at higher levels afte

272 All the expected 8:2 FTOH degradation products were detected including 8:2 fluorot

273 phenylalanine for the lipid, and amino acid degradation products were formed, among which alpha-keto

274 A range of intermediates and degradation products were identified and matched to the

275 Finally, several ENs degradation products were identified using the technique

276 ater-soluble proteins (WSP), all five listed degradation products were identified.

277 Microtox-tests revealed that degradation products were less toxic toward the bacteriu

278 acy and current-use pesticides and pesticide degradation products were measured in pine needles along

279 Anthocyanins and some of their degradation products were monitored and quantified using

280 riations of the phenolic compounds and their degradation products were monitored over time.

281 tion of 5-hydroxymethylfurfural (HMF) and AC degradation products were monitored using HPLC-DAD-MS(n)

282 Polymer degradation products were non-toxic.

283 l commercially-available vehicles, and their degradation products were not cytotoxic to cells at the

284 ontrast, no negative effects of the two main degradation products were observed.

285 ers were also degraded, and the polymers and degradation products were shown to be noncytotoxic.

286 Both degradation products were sorbed to the two soils to a s

287 uantities of cleaved pyrin and IkappaB-alpha degradation products were substantially increased in leu

288 The identified degradation products were unambiguously confirmed by tan

289 As most of the chemical structures of the degradation products were unknown, enhanced mass defect

290 Reduced levels of D-dimer (fibrin degradation product) were evident in ticks fed on immuno

291 hermal treatment (180-260 degrees C) and the degradation products where monitored over time (0-24h).

292 These degradation products, which contained almost the same se

293 is extracellular ATP and its ecto-enzymatic degradation products, which function as signaling molecu

294 lar matrix acts as a mechanical support, its degradation products, which mainly accumulate during agi

295 tem allowed higher removals for 34 out of 55 degradation products while for only 4 compounds the poli

296 s in a specific, transcriptionally inactive, degradation product with altered self-association proper

297 Trapping a hitherto unknown degradation product with OPD yielded 1,4-bis(1H-benzo[d]

298 gest that histones and DNA bind large fibrin degradation products with 191 and 136 nM dissociation co

299 mechanism based on random association of RNA degradation products with Argonaute triggers siRNA ampli

300 configuration analysis and comparison of its degradation products with synthetic controls.