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1 tle is known about how miRNAs themselves are degraded.
2 re translocated into the core particle to be degraded.
3 transit peptide (rCTP) and were subsequently degraded.
4 and the truncated species are uridylated and degraded.
5 ximity to mitochondria and are lipolytically degraded.
6 bud, Myo2 releases the vacuole, and Vac17 is degraded.
7 compounds of technical toxaphene (CTTs) are degraded.
8 ed to exit the endoplasmic reticulum and was degraded.
9 as lower and the released compounds were not degraded.
10 which vision through the nondominant eye is degraded.
11 but we show here that NrnA is bidirectional, degrading 2-5 nucleotide long RNA oligomers from the 3'
14 val using 12 variables or less while the PAH-degrading activity of strain LH128 in soils that show su
15 in acidic and basic environments and do not degrade after immersing in solutions with extreme pH (pH
16 rees C (500 m) with 65-89% of each component degraded after 50 days compared to 0-47% degradation at
17 the attached Z-band-bound thin filaments are degraded after ubiquitination by the ubiquitin ligase tr
20 ed from inhibition by alpha2-antiplasmin and degrades amorphous protein aggregates to release smaller
22 bility of PCB transforming microorganisms to degrade and reduce the overall concentration of PCBs in
23 box-cullin (SCF) E3 ubiquitin ligases, which degrade and suppress steady-state LT protein levels.
24 Such cements remain in the tooth and fail to degrade and thus normal mineral volume is never complete
27 ncing age, damaged proteins are more quickly degraded and replaced, maintaining proteome fidelity.
29 ndency on linker length was observed for BET-degrading and cMyc-driven antiproliferative activities i
31 romotes the invasion of T24 cells in part by degrading anti-invasive miRNAs so as to up-regulate the
34 vaccines, antibodies, and enzymes, typically degrade at room temperature over time due to denaturatio
36 The potential role of phyllospheric CH3Cl-degrading bacteria as a filter for plant emissions of CH
37 DNA-SIP and to characterise marine isoprene-degrading bacteria at the physiological and molecular le
38 poration at the single-cell level, with DMSP-degrading bacteria containing seven times more (34)S tha
41 Functional genes from the three major VC-degrading bacterial guilds were present in 99% and expre
43 tests, both Xyl1 and Xyl2 were effective in degrading beechwood xylan to produce xylo-oligosaccharid
48 as nonsense-mediated mRNA decay (NMD), which degrades both abnormal as well as some normal transcript
49 t adaptors of the ClpXP protease are readily degraded but that cargo binding inhibits this degradatio
50 Specifically, AFM-based SMFS data quality is degraded by a commercial cantilever's limited combinatio
52 ed particles can efficiently saturate and be degraded by a restricting TRIM5 protein, indicating that
54 the pro-apoptotic factors FoxO1/3 are overly degraded by acetylated Skp2, resulting in polyploid cell
55 ent neuroprogenitors in vivo MCPH1 itself is degraded by APC/C(C)(dh1), but not APC/C(C)(dc20), in la
56 properties of these emitters are frequently degraded by blinking and photobleaching that arise from
62 SPOP-CUL3 substrates that are preferentially degraded by endometrial cancer-associated SPOP mutants.
64 cause aberrant and excess ncRNAs are largely degraded by exoribonucleases, a key characteristic of th
69 unds from various sources and localizations, degraded by propagation through the environment, sum to
70 es in the 20-40-mer length range are rapidly degraded by proteases, which may limit their biomedical
72 mination between the classes is artificially degraded by replacing the SVM model with an ad hoc k-mea
74 ); next, organic substrates are oxidized and degraded by serving as electron donors to reduce State I
75 , the unprotected newly replicated genome is degraded by the exonuclease activity of MRE11, and the f
77 GF-beta, cell surface-internalized FN is not degraded by the lysosome but instead undergoes recycling
82 the plasma membrane in erythroblasts and are degraded by the orthochromatic stage of differentiation.
84 aN-on-Silicon electronic devices is severely degraded by the presence of a parasitic conduction pathw
85 tants, suggesting that ubiquitinated PEX5 is degraded by the proteasome when the function of PEX6 or
86 quitinated, extracted from the membrane, and degraded by the proteasome-a pathway termed endoplasmic
90 ribosome stalling, and the arrest product is degraded by the ribosome-mediated quality control (RQC)
92 rget genes and causing the transcripts to be degraded by the RNA-induced silencing complex (RISC).
94 odulates RmcA activity such that the protein degrades c-di-GMP and thereby inhibits matrix production
95 the remarkable ability of R. flavefaciens to degrade carbohydrates in the bovine rumen and provides a
96 se cases, meaning the marine enzymes used to degrade carrageenans must possess unique features to rec
99 esive, proliferative, chemotactic and matrix-degrading characteristics and differential responsivenes
100 relate with scavenging; although Q301E(7.39) degraded chemokines in the absence of arrestin, S103D(2.
105 at, flame, and chemical agents that normally degrade conventional macrofibers, high-performance macro
106 arkably, the failure of ACKR3 R142(3.50)A to degrade CXCL11 was not caused by the lack of arrestin re
111 is an intracellular enzyme that specifically degrades deoxynucleoside triphosphates into component nu
112 KLK5 has biological functions that include degrading desmosomal proteins and inducing proinflammato
113 und that overstressed LEDs show irreversibly degraded device performance, possibly because ions initi
115 um Bacteroidetes depends on their ability to degrade dietary glycans that cannot be metabolized by th
116 uses that encode an ExoN, which functions to degrade double-stranded RNA (dsRNA) replication intermed
118 s Parque Nacional da Gorongosa highlight how degraded ecosystems can be rehabilitated, expanded, and
120 uring of compounds, but does not necessarily degrade electrochemical cycling stability or performance
121 Here, we present Trim-Away, a technique to degrade endogenous proteins acutely in mammalian cells w
122 icroglia during morphine withdrawal and that degrading endogenous spinal ATP by administering apyrase
123 and anti-angiogenic cytokines and gradually degrade endosteal endothelium, stromal cells, and osteob
125 inhibitors or genetic overexpression of PGE2-degrading enzyme 15-hydroxyprostaglandin dehydrogenase (
127 d and characterized as a presequence peptide degrading enzyme in the matrix.Protein localization play
129 tion factors, and the tolerogenic tryptophan-degrading enzyme indoleamine 2,3-dioxygenase (IDO) were
130 ular arginine and targetable by the arginine-degrading enzyme pegylated arginine deiminase (ADI-PEG 2
131 Similarly, knockout mice lacking the LPA-degrading enzyme phospholipid phosphate phosphatase type
132 Ste23 in yeast, a homologue of human insulin-degrading enzyme, which is required for efficient peptid
133 erase chain reaction of extracellular purine degrading enzymes and P1 and P2 receptors on T cells iso
134 uctures for almost all H. jecorina cellulose-degrading enzymes are available, except for HjLPMO9A, be
136 on of FAEs and ECs through the inhibition of degrading enzymes has been considered to be a viable the
139 ue progression renders macrophages unable to degrade exogenous atherogenic material and endogenous ca
140 emodeling and acute inflammation not only by degrading extracellular matrix proteins but also by cont
141 tingly, the best mutants are also capable of degrading fensulfothion, which is reported to be an inhi
142 pecificity, because unlike r-tPA, it did not degrade fibrinogen or enhance experimental bleeding.
144 orests, indicating that not all disturbed or degraded forest is of equal value for the long-term sust
145 densities were 47% higher in primary versus degraded forests and, unexpectedly, increased 4.9% per y
151 cent proteomic approaches suggested that Vpr degrades helicase-like transcription factor (HLTF) DNA h
152 influences that probably include binding of degraded hemoglobin, among other things, that significan
153 icits in lysosomal enzymes that specifically degrade heparan sulfate, a sulfated glycosaminoglycan.
155 d disrupts the first line of host defense by degrading human mucin-2 (MUC2), depleting mucin stores a
156 strated for the first time that P. australis degrades IBP from water and is therefore a suitable spec
159 Moreover, the OsbZIP48 protein does not degrade in dark-grown rice and Athy5 seedlings complemen
160 gs show that white matter tract integrity is degraded in areas where T-cell infiltration is highest,
167 describe how reversed replication forks are degraded in the absence of BRCA2, and a MUS81 and POLD3-
169 while most of L1 protein dissociates and is degraded in the endosome, some L1 protein remains associ
171 rk architectures and their functionality are degraded in the presence of focal axonal swellings (FAS)
174 y, by the FPR2 antagonist WRW4 Thus, SAA1 is degraded into fragments lacking chemokine-inducing capac
175 -1) s(-1)), although some N-monochlorovaline degraded into isobutyraldehyde (1.0 x 10(-4) s(-1)).
176 The N,N-dichlorovaline then competitively degraded into isobutyronitrile (1.3 x 10(-4) s(-1)) and
177 )-CRISPR-associated (Cas) systems detect and degrade invasive genetic elements by an RNA-guided, RNA-
179 s to enhance productivity and SOC storage in degraded lands through improved management practices.
181 modulation of ordered structures, through to degrading large, amorphous structures into short, chain-
182 GAT (diacylglycerol O-acyltransferase 1) and degrade LD via ATGL (adipocyte triglyceride lipase) afte
188 (WM), a grassland meadow (GM), a moderately degraded meadow (MDM) and a severely degraded meadow (SD
191 The use of enzyme cocktails produced from PB-degrading microbial consortia (PB-dmc) is a promising ap
195 anced oxidation processes (AOPs) effectively degrade N-nitrosodimethylamine (NDMA) passing through re
196 Intracellular BENSpm generated from the degraded nanoparticles induced the expression of rate-li
199 of transcripts lacking exon 7 and a rapidly degraded non-functional SMNDelta7 protein, but from whic
200 asomes lacking Usp14 are much more active in degrading non-ubiquitinated proteins (e.g. Sic1) than WT
204 ntial and conserved protein complex that can degrade or process RNA substrates in the 3'-to-5' direct
205 trinsically disordered and is either rapidly degraded or forms amyloid in a lysosome-initiated proces
206 unctions for a designed time period and then degrades or destructs, holds promise in medical implants
207 elected strains exhibited a great ability to degrade organic polymers in vitro as well as possibly pr
208 ve photocatalytic activities for efficiently degrading organic compounds in contaminated water such a
210 tar resources from flowering plants; and (c) degraded overwintering forest habitats due to commercial
212 the authors show that TTP, encoded by Zfp36, degrades p28 to inhibit IL-27 production by macrophages
213 mediation strategies were most effective for degrading PAHs and estimated the cancer risks associated
216 s system, we analysed waters from intact and degraded peat swamp forest of Kalimantan, Indonesian Bor
217 nhances the efficiency of Fenton reaction to degrade pectin into 5.5 kDa within only 35 minutes.
218 study investigated whether DypB, the lignin-degrading peroxidase from Rodococcus jostii, depolymeriz
219 different because the bacterial strain alone degraded phenanthrene with sigmoidal kinetics but could
220 a leaf beetle's (Cassida rubiginosa) pectin-degrading phenotype, we demonstrate its dependency on an
221 yclase activation and inhibition of the cGMP-degrading phosphodiesterase-5, ischemic preconditioning,
222 black aspergilli, alternative approaches for degrading plant biomass, and indications for the genetic
224 Bioremediation uses soil microorganisms to degrade polycyclic aromatic hydrocarbons (PAHs) into les
229 e proteasome, the multisubunit protease that degrades proteins in the nucleus and cytoplasm, in homol
231 The results show that some biocides are degraded rapidly in soil (e.g., isothiazolinones: T1/2 <
233 ous fishes, yet how these findings relate to degraded reef systems where fish diversity and abundance
236 eron beta (IFN-beta) by interacting with and degrading retinoic acid-inducible gene I (RIG-I) and mel
239 enes used by the symbiotic Cycloclasticus to degrade short-chain alkanes and those of free-living Cyc
240 slow/theta activity that is correlated with degraded single-neuron responses and with baseline theta
243 ional potential significantly altered in the degraded soils with bacterial wilt (termed as degraded s
246 expresses extracellular enzymes in order to degrade SOM and transfer N contained therein to its host
247 ential to produce extracellular enzymes that degrade SOM, calling into question the ubiquity of the p
249 lusory phonemes), and also identification of degraded speech, while manipulating audiovisual asynchro
250 is degraded over time, dentine replaces the degraded sponge leading to a complete, effective natural
253 ing community, and it showed a preference to degrade substituted and non-substituted polycyclic aroma
254 -ICs were degraded in moDCs, B cells did not degrade the complexes but recycled them in native form t
256 iota may trigger immune responses as well as degrade the host mucosa, processes that ultimately incre
258 ples with LN2 for increasing amounts of time degraded the strength of coal within a certain limit.
260 teasome is a large multisubunit complex that degrades the majority of proteins in the cell under norm
261 triphosphate diphosphohydrolase 1 (NTPDase1) degrades the purines ATP and ADP that are key regulators
262 , leakage of plasticity to adjacent synapses degrades the recognition of sparse static patterns.
263 gdpP, which encodes a phosphodiesterase that degrades the second messenger cyclic-di-AMP, and xdrA, t
265 to chemotaxis by binding, internalizing, and degrading the chemokines CXCL11 and CXCL12 to shape and
267 econdary anti-inflammatory role for LTA4H in degrading the neutrophil chemoattractant Pro-Gly-Pro (PG
268 ation with dedicated bacteria specialized in degrading the pollutant is suggested as a green and econ
271 namics gets dominated by nonlinearities that degrade their performance, for instance in sensing appli
273 espond to exogenously applied dsRNAs, either degrading them or failing to import them into the cytopl
274 mature termination codons (PTCs) are rapidly degraded through nonsense-mediated mRNA decay (NMD).
278 tion of cortical cholinergic activity in STs degrades top-down executive control over behavior, produ
280 und that approximately 400 nm long nanotubes degraded under the gentlest flow conditions while approx
281 pathways sculpt eukaryotic transcriptomes by degrading unneeded, defective, and potentially harmful n
286 ndicate that ADAMTS-4 induces SMC apoptosis, degrades versican, promotes inflammatory cell infiltrati
289 zones subjected to redox oscillations, VC is degraded via coexisting aerobic ethenotrophic and anaero
293 Single amino acid changes in the SAMHD1-degrading Vpx mac239 allowed it to enhance early postent
295 en that GHG emissions in tidally-restricted, degraded wetlands are caused by human activity, they are
296 hich synthesizes a cholesterol precursor, is degraded when cholesterol levels in the endoplasmic reti
299 a endocytosis, and become entrapped and then degraded within endolysosomes, which can significantly i
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