ライフサイエンスコーパス: dehydrogenase

1 alysis of allosterically inhibited L-lactate dehydrogenase.

2 the rate-limiting enzyme glucose-6-phosphate dehydrogenase.

3 bstrates include the short-lived Mdh2 malate dehydrogenase.

4 catalyzed by an ene-reductase and an alcohol dehydrogenase.

5 ruvate dehydrogenase and alpha-ketoglutarate dehydrogenase.

6 e dehydrogenase, and branched-chain ketoacid dehydrogenase.

7 lation of the key metabolic enzyme, pyruvate dehydrogenase.

8 eased activity of glyceraldehyde 3-phosphate dehydrogenase.

9 brates, in addition to a specialized alcohol dehydrogenase.

10 ctively inhibits the parasite dihydroorotate dehydrogenase.

11 the study of reaction landscapes is lactate dehydrogenase.

12 lytic proteins such as d-glucose-6-phosphate dehydrogenase.

13 trans-chrysanthemol and trans-chrysanthemal dehydrogenases.

14 e 'RED' family of reductases, epimerases and dehydrogenases.

15 talyzed by one or more 17beta-hydroxysteroid dehydrogenases.

16 d at targeting glycolysis must consider both dehydrogenases.

17 bacterial genomes encoding a large number of dehydrogenases.

18 major Amb a 1 allergens, and as unique, NADH dehydrogenases.

19 m cell associated markers including aldehyde dehydrogenase 1 (ALDH1).

20 Aldehyde dehydrogenase 1 (ALDH1A1)-positive dopaminergic (DA) neu

21 om the host cell, glyceraldehyde-3-phosphate dehydrogenase 1 (GAPDH1), which is primary a glycolysis

22 port that a glutaminolytic enzyme, glutamate dehydrogenase 1 (GDH1), upregulated upon detachment via

23 icient PDAC cell lines identified isocitrate dehydrogenase 1 (IDH1) as the sole antioxidant enzyme un

24 Hotspot mutations in the isocitrate dehydrogenase 1 (IDH1) gene occur in a number of human c

25 dulate the activity of the enzyme isocitrate dehydrogenase 1 (IDH1).

26 vated primary T cells, that cytosolic malate dehydrogenase 1 (MDH1) is an alternative to LDH as a sup

27 Methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) and serine hydroxymethyltransfe

28 Isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) are key metabolic

29 ations in IDH1 and IDH2 (encoding isocitrate dehydrogenase 1 and 2) drive the development of gliomas

30 relative abundance of 11-beta-hydroxysteroid dehydrogenase 1 mRNA in HG explants suggests glucose inv

31 2007 tumor grade, histology, and isocitrate dehydrogenase 1 R132H mutational status.

32 loacetate shuttle and a glycerol-3-phosphate dehydrogenase 1(Gpd1p)-dependent shuttle are able to mai

33 EtOH-metabolizing enzymes, including alcohol dehydrogenase 1, aldehyde dehydrogenase 1A1, and catalas

34 PTS2-containing enzyme Glycerol-3-phosphate dehydrogenase 1, Gpd1.

35 produced at high levels by mutant isocitrate dehydrogenase 1/2 (IDH1/2) enzymes, was reported as an o

36 Gliomas harboring mutations in isocitrate dehydrogenase 1/2 (IDH1/2) have the CpG island methylato

37 Xanthine dehydrogenase-1 silencing in Aedes aegypti mosquitoes pr

38 Here, we sought to determine whether retinol dehydrogenase 10 (RDH10), upregulated in rod/cone hybrid

39 ast two subunits of NAD(+)-dependent retinol dehydrogenase 10 (RDH10), which catalyzes the oxidation

40 mediated by an increase in 15-prostaglandin dehydrogenase (15-Pgdh) activity, which oxidizes and ina

41 ls, we also found increased 15-Prostaglandin Dehydrogenase (15-PGDH) expression as well as increased

42 GE2-degrading enzyme 15-hydroxyprostaglandin dehydrogenase (15-PGDH), resulted in reduced PD-L1 expre

43 s for repression of 15-hydroxy prostaglandin dehydrogenase (15-PGDH).

44 including alcohol dehydrogenase 1, aldehyde dehydrogenase 1A1, and catalase, as well as the microsom

45 ressing IL-10, TGF-beta, IL-27, and aldehyde dehydrogenase 1A2 but not IL-12 or IL-35; IL-10 and TGF-

46 Aldehyde dehydrogenase 2 (ALDH2), one of 19 ALDH superfamily memb

47 Mitochondrial isocitrate dehydrogenase 2 (IDH2) converts NADP(+) to NADPH and pro

48 Recurrent mutations in isocitrate dehydrogenase 2 (IDH2) occur in approximately 12% of pat

49 ent mutations at R140 and R172 in isocitrate dehydrogenase 2 (IDH2) occur in many cancers, including

50 emonstrate that MitEpac1 inhibits isocitrate dehydrogenase 2 via the mitochondrial recruitment of CaM

51 MFR, mediating loss of 11beta-hydroxysteroid dehydrogenase-2 (11beta-HSD2), which otherwise inactivat

52 ponses and enables identification of alcohol dehydrogenase 5 (ADH5) as an enzyme that regulates FA me

53 received D + T with baseline normal lactate dehydrogenase (5 years, 45%) and normal lactate dehydrog

54 3 +/- 16.6 vs 24.5 +/- 16.8U/L), and lactate dehydrogenase (510.8 +/- 33 vs 292.4 +/- 29).

55 key oxidative PPP enzyme, 6-phosphogluconate dehydrogenase (6PGD), using our novel small-molecule 6PG

56 Lactate dehydrogenase A (LDHA) has been reported to be involved

57 hosphorylation-induced activation of lactate dehydrogenase A (LDHA), an enzyme that catalyses the int

58 enzymes, with notable expression of lactate dehydrogenase A occurring in the airway epithelium.

59 s VEGF-A, glucose transporter-1, and lactate dehydrogenase A.

60 through the common subunit dihydrolipoamide dehydrogenase, a flavoprotein encoded by the gene lpdG A

61 ylation of mitochondrial long-chain acyl-CoA dehydrogenase, a known SIRT3 deacetylation target; impro

62 ontributions of macrophage-expressed lactate dehydrogenase-A (LDH-A) to tumor formation in a K-Ras mu

63 ses (AAO) and the intracellular aryl-alcohol dehydrogenases (AAD) were also produced after exposure t

64 et genes to be the aminoadipate-semialdehyde dehydrogenase AASDH and the solute transporter SLC9A8 Ou

65 e (PRODH) and l-glutamate-gamma-semialdehyde dehydrogenase active sites.

66 oxygen species (ROS); 2) decrease succinate dehydrogenase activity (complex II of the electron trans

67 ectron transport function from its succinate dehydrogenase activity also suggested a mechanism by whi

68 calcium ([Ca(2+)]mito), inhibiting pyruvate dehydrogenase activity and glucose oxidation, while incr

69 correlated significantly with higher lactate dehydrogenase activity and mRNA expression of Ldha, Mct1

70 ed membrane potential, increased respiratory dehydrogenase activity and slightly elevated oxygen cons

71 tiation by attenuating medium-chain acyl-CoA dehydrogenase activity and that inhibition of this axis

72 peroxisomal NAD(+) required for saccharopine dehydrogenase activity can be sustained by both shuttles

73 Our objective was to demonstrate how dehydrogenase activity could be assessed within the myoc

74 he electron acceptor and a small increase in dehydrogenase activity employing an artificial electron

75 , tricarboxylic acid metabolism and pyruvate dehydrogenase activity for ATP-dependent thermogenesis t

76 tipotent epithelial cells with high Aldehyde dehydrogenase activity have been previously reported to

77 In contrast, pyruvate dehydrogenase activity is significantly decreased regard

78 ns, hypohomocysteinaemia and increased G-6-P-dehydrogenase activity will facilitate early diagnosis a

79 ression of pluripotency-factors and aldehyde dehydrogenase activity.

80 tical non-destructive approach for assessing dehydrogenase activity.

81 igned and investigated bioanode with alcohol dehydrogenase (ADH) catalysing oxidation of glycerol and

82 oxidation of geraniol to geranial by alcohol dehydrogenase ADH3, followed by the enantioselective red

83 spore coat of C. difficile These include two dehydrogenases, AdhE1 and LdhA, as well as the CdeC prot

84 Aldehyde/alcohol dehydrogenases (ADHEs) are bifunctional enzymes that com

85 mined by tumor sphere formation and aldehyde dehydrogenase (ALDH) activity (Aldefluor) assays.

86 arcosphere generation, chemodrug or aldehyde dehydrogenase (ALDH) activity selection.

87 cancer stem-like associated enzyme aldehyde dehydrogenase (ALDH).

88 entified and cloned a novel cinnamyl alcohol dehydrogenase allele (SbCAD2) that has an 8-bp deletion

89 Here we show that the alpha-ketoglutarate dehydrogenase (alpha-KGDH) complex is localized in the n

90 in heavy chain 1, glyceraldehyde-3-phosphate dehydrogenase, alpha-enolase, filamin-A, and heat shock

91 dehydrogenase complexes, including pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, and br

92 rial that inhibits plasmodial dihydroorotate dehydrogenase, an enzyme essential for pyrimidine biosyn

93 ved in natural product metabolism-an alcohol dehydrogenase and a cytochrome P450-produces unexpected

94 that conversion is performed by an acyl-CoA dehydrogenase and a subsequent hydratase yielding an int

95 ption of two key TCA cycle enzymes, pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase.

96 s, which is regulated by glucose-6-phosphate dehydrogenase and AMP kinase.

97 Cellular injury markers lactate dehydrogenase and aspartate aminotransferase were persis

98 y optical imaging and by analysis of lactate dehydrogenase and caspase-cleaved cytokeratin 18 in the

99 2, a mitochondrial methylenetetrahydrofolate dehydrogenase and cyclohydrolase involved in one-carbon

100 re suitable sources of peptidases, glutamate dehydrogenase and cystathionine gamma-lyase.

101 uclear complex of glyceraldehyde-3-phosphate dehydrogenase and DNA repair enzyme apurinic/apyrimidini

102 In this shunt glucose dehydrogenase and gluconate kinase catalyze the two-step

103 N(tz)ADH to be substrates for yeast alcohol dehydrogenase and lactate dehydrogenase, respectively, w

104 ation results in a weak induction of alcohol dehydrogenase and other anaerobic genes.

105 version to N(tz) ADPH by glucose-6-phosphate dehydrogenase and reoxidation to N(tz) ADP(+) by glutath

106 he vitamin A-converting enzyme retinaldehyde dehydrogenase and specialized in forkhead box p3-positiv

107 cter jejuni, possesses a periplasmic formate dehydrogenase and two terminal oxidases, which serve to

108 liferating NK cells did not express aldehyde dehydrogenase and were killed by Cy in vitro.

109 molybdenum- and tungsten-containing formate dehydrogenases and related enzymes likely operate via a

110 regnancy lead to inhibition of PDH (pyruvate dehydrogenase) and pyruvate flux into the tricarboxylic

111 hisms (ie, hemoglobin S, glucose-6-phosphate dehydrogenase, and alpha-thalassemia) were the only ones

112 pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, and branched-chain ketoacid dehydrogenase

113 ent of PRODH, l-glutamate-gamma-semialdehyde dehydrogenase, and C-terminal domains, including an exte

114 vels of alanine aminotransferase and lactate dehydrogenase, and inflammatory mediators such as monocy

115 ys, such as glycolysis, flux through lactate dehydrogenase, and the citric acid cycle (as inferred by

116 Pyruvate and 2-oxoglutarate dehydrogenases are substituted by 'ancient' CoA-dependen

117 ose transport and glyceraldehyde-3-phosphate dehydrogenase as the most selective antiparasitic target

118 d by increased creatinine kinase and lactate dehydrogenase, as well as expression of monocyte chemoat

119 gars and phenolic compounds, and the lactate dehydrogenase assay was invalidated by honey oxidising t

120 ification of a putative 3-hydroxyisobutyrate dehydrogenase, AtHDH1 (At4g20930), involved in Val degra

121 ble, low cost, and portable various types of dehydrogenase based biosensor devices using metal oxide

122 e highest currently reported for the alcohol dehydrogenase bioanodes operating utilizing a direct ele

123 trate that the reaction landscape of lactate dehydrogenase branches at multiple points creating pathw

124 hydes by oxidation is attributed to aldehyde dehydrogenases but never to aldehyde oxidases.

125 Cinnamyl alcohol dehydrogenase (CAD) catalyzes the final step in monolign

126 e synthesized in mammalian cells via choline dehydrogenase (CHDH; EC 1.1.99.1), we assessed whether t

127 t catalyses this reaction is carbon monoxide dehydrogenase (CODH).

128 ped via direct attachment of NAD(+)-glycerol dehydrogenase coenzyme-apoenzyme complex onto supporting

129 Typically, dehydrogenase cofactor binding sites are open to solvent

130 erated by using PfHRP2/Pf-Plasmodium lactate dehydrogenase combination RDTs.

131 The succinate dehydrogenase complex (complex II) is a highly conserved

132 The human pyruvate dehydrogenase complex (PDC) comprises four multidomain c

133 The pyruvate dehydrogenase complex (PDC) is a critical mitochondrial

134 The pyruvate dehydrogenase complex (PDC) is the primary metabolic che

135 d the E1beta and E2 subunits of the pyruvate dehydrogenase complex (PDC).

136 micry between the E2 subunit of the pyruvate dehydrogenase complex (PDC-E2), the major mitochondrial

137 The phosphoenolpyruvate dehydrogenase complex is also up-regulated, leading to t

138 We demonstrate that the chloroplast NADPH dehydrogenase complex, a homolog to respiratory Complex

139 e E2 subcomponent of the alpha-ketoglutarate dehydrogenase complex, a rate-controlling tricarboxylic

140 SDHD encodes subunit D of the succinate dehydrogenase complex, an integral membrane protein.

141 ss of PDHK4, a key regulator of the pyruvate dehydrogenase complex, caused a profound cell growth inh

142 talysis by multiple mitochondrial 2-ketoacid dehydrogenase complexes, including pyruvate dehydrogenas

143 was undertaken against the respiratory chain dehydrogenase component, NADH:menaquinone oxidoreductase

144 NAD(P)H dehydrogenases comprise type 1 (NDH-1) and type 2 (NDH-2

145 enzyme as assessed by a lipoamide-lipoamide dehydrogenase-coupled assay.

146 emia in individuals with glucose-6-phosphate dehydrogenase deficiency (G6PDd).

147 study, a novel fungus FAD dependent glucose dehydrogenase, derived from Aspergillus niger (AnGDH), w

148 ression of the Drosophila homolog of lactate dehydrogenase (dLdh).

149 st subcomplex (IIa) represents the succinate dehydrogenase domain composed of SDH1 and SDH2.

150 lavin reductase Fre, which is related to the dehydrogenase domain of eukaryotic NOX enzymes, as an ef

151 transmembrane domain and the NADPH-oxidizing dehydrogenase domain.

152 imidine catabolic pathway, dihydropyrimidine dehydrogenase (DPYD) and its effect on pharmacokinetics

153 allow for pathway variations in the complete dehydrogenase-driven TCA cycle that could support anaero

154 of a putative branched-chain alpha-ketoacid dehydrogenase E1 beta-subunit-encoding gene (NaBCKDE1B)

155 nit of the metabolic enzyme complex pyruvate dehydrogenase (E2-PDH) with a fatty acid derivative, lip

156 national Prognostic Index, including lactate dehydrogenase, Eastern Cooperative Oncology Group perfor

157 AspRedAm) was combined with a single alcohol dehydrogenase (either metagenomic ADH-150, an ADH from S

158 A putative xylitol dehydrogenase, encoded by Clo1313_0076, was also deleted

159 Specific oxygen uptake rates and dehydrogenase enzyme activity results indicated that CAP

160 DK1) protein levels and a decreased pyruvate dehydrogenase enzyme activity.

161 The study was performed using the alcohol dehydrogenase enzyme immobilised by covalent binding thr

162 nctionalized with glutaraldehyde and lactate dehydrogenase enzyme was immobilized on the aldehyde ter

163 Reduction of NAD(+) by dehydrogenase enzymes to form NADH is a key component of

164 ults yields an unprecedented view of lactate dehydrogenase enzymology, confirming the timescale of su

165 er oxidative PPP enzyme, glucose-6-phosphate dehydrogenase, exhibit non-immune hemolytic anemia upon

166 ciated with increased expression of aldehyde dehydrogenase family 1 subfamily A1 (Aldh1a1).

167 and activity of the donor complexes formate dehydrogenase (FdhABC) and hydrogenase (HydABCD) as well

168 hermophilus or soluble PQQ-dependent glucose dehydrogenase from Acinetobacter calcoaceticus.

169 d by the immobilisation of either cellobiose dehydrogenase from Corynascus thermophiles or bilirubin

170 t electron transfer (DET) between cellobiose dehydrogenase from Corynascus thermophilus (CtCDH) and a

171 ained by either immobilisation of cellobiose dehydrogenase from Corynascus thermophilus or soluble PQ

172 The ability of the FdsABG formate dehydrogenase from Cupriavidus necator (formerly known a

173 Glucose-6-phosphate dehydrogenase (G6PD) activity is essential for redox equ

174 Glucose-6-phosphate dehydrogenase (G6PD) deficiency is believed to confer pr

175 Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzym

176 Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzym

177 rs, and we also assessed glucose-6-phosphate dehydrogenase (G6PD) enzyme activity.

178 hereas chloroquine and a glucose-6-phosphate dehydrogenase (G6PD) inhibitor affected the cytosol; 24

179 Glucose-6-phosphate dehydrogenase (G6PD) status was determined using a rapid

180 action of nuclear glyceraldehyde-3-phosphate dehydrogenase (GAPDH) with apurinic/apyrimidinic endonuc

181 Commonly used glyceraldehyde-3-phosphate dehydrogenase (Gapdh), beta-actin (Actb), or beta2-micro

182 oyed nanoporous gold (NPG) supported glucose dehydrogenase (GDH) bioanode, immobilised with the assis

183 adenine dinucleotide (FAD) dependent glucose dehydrogenase (GDH) is a thermostable, oxygen insensitiv

184 and in vivo, whereas activation of glutamate dehydrogenase (GDH) was required to stimulate insulin se

185 From 2-step testing, all glutamate dehydrogenase (GDH)-positive specimens, regardless of fe

186 Notably, expression of glutamate dehydrogenase GDH2, a hominoid-specific enzyme with rela

187 With syngas, the upregulated (R)-lactate dehydrogenase gene represents a route of electron transf

188 Germline variants in succinate dehydrogenase genes (SDHx) co-occurring with PTEN germli

189 Mutations in the isocitrate dehydrogenase genes IDH1 and IDH2 are among the first ge

190 olecular substitution in duplicated pyruvate dehydrogenase genes that underpins one of the most extre

191 mobility group box-1 [HMGB1], and glutamate dehydrogenase [GLDH]).

192 G3P dehydrogenase (GPDH) mediates G3P synthesis, but the rol

193 creatine kinase, glyceraldehyde-3-phosphate dehydrogenase (GPDH), calcium-binding protein, and phosp

194 Molybdenum-containing formate dehydrogenase H from Escherichia coli (EcFDH-H) is a pow

195 need for pain medication, and higher lactate dehydrogenase had a negative impact on the therapeutic r

196 l-band (histidine-rich protein-2/pan-lactate dehydrogenase [HRP2/pLDH]) rapid diagnostic test (RDT) t

197 rate lyase) or the TCA cycle (via isocitrate dehydrogenase (ICDH) activity) and we sought to better u

198 mutations in the metabolic enzyme isocitrate dehydrogenase (IDH) in subsets of cancers, including sec

199 subset of glioblastomas harboring isocitrate dehydrogenase (IDH) mutations, but metabolic alterations

200 with MYC signaling, but not with isocitrate dehydrogenase (IDH) mutations, suggesting a distinct mec

201 We dissected these influences in isocitrate dehydrogenase (IDH)-mutant gliomas by combining 14,226 s

202 fined invasive phenotypes of both isocitrate dehydrogenase (IDH-1)-mutated and IDH-1 wild-type gliobl

203 Here, we report that the isocitrate dehydrogenase IDH1 is the most strongly upregulated NADP

204 de biosynthetic enzyme inosine monophosphate dehydrogenase (IMPDH) forms octamers that polymerize int

205 Inosine-5'-monophosphate dehydrogenase (IMPDH) is an essential enzyme for nucleot

206 ed genes, including a succinate-semialdehyde dehydrogenase in the gamma-aminobutyric acid shunt pathw

207 pport for the presence of an active pyruvate dehydrogenase in this stage.

208 e and mutations in genes encoding isocitrate dehydrogenases (in approximately 60% of iCCAs) or amplif

209 -2HG-producing mitochondrial enzyme, alcohol dehydrogenase, iron-containing protein 1 (ADHFE1), is a

210 e biosynthesis is restored when saccharopine dehydrogenase is mislocalised to the cytosol in mdh3/gpd

211 In humans, the enzyme pyruvate dehydrogenase is transiently nuclear at the 4/8-cell sta

212 e, kd) for compounds binding to the pyruvate dehydrogenase kinase (PDHK) enzyme.

213 Here, we show that pyruvate dehydrogenase kinase 1 (PDK1) is enriched in breast canc

214 which were paralleled by increased pyruvate dehydrogenase kinase 1 (PDK1) protein levels and a decre

215 l glycolytic enzymes (hexokinase II, pyruvic dehydrogenase kinase 1 and pyruvic kinase M2), We sugges

216 s driven by robust up-regulation of pyruvate dehydrogenase kinase 4 (PDK4) and phosphorylation-depend

217 and glycogen content, and increased pyruvate dehydrogenase kinase 4 mRNA abundance in the heart, EDL

218 hormone progesterone induces PDK4 (pyruvate dehydrogenase kinase 4) in cardiomyocytes and that eleva

219 ha increased glycolytic enzymes and pyruvate dehydrogenase kinase-1 (PDK-1), which reduces mitochondr

220 fore, interpreting T-jump results of lactate dehydrogenase kinetics has required extensive computatio

221 ed by a mutation in the l-2-hydroxyglutarate dehydrogenase (L2HGDH) gene.

222 We identified lactate dehydrogenase (LDH) as a new functional target of AMPKal

223 Cellular viability, autophagy, lactate dehydrogenase (LDH) assay, and mammalian target of rapam

224 nyl tetrazolium bromide (MTT) assay, lactate dehydrogenase (LDH) release assay, Hoechst 33342 stainin

225 d to the terminal glycolytic enzyme, lactate dehydrogenase (LDH).

226 f pyrazole-based inhibitors of human lactate dehydrogenase (LDH).

227 esolution crystal structures of the aldehyde dehydrogenase lead to a revised reaction mechanism.

228 LLH was defined by a discharge lactate dehydrogenase level of 400 to 700 U/L.

229 uminemia, thrombocytopenia, and high lactate dehydrogenase level, yielded a better C statistic of 0.6

230 metastases (20% v 14%) and increased lactate dehydrogenase levels (52% v 38%) at baseline; 41% of pat

231 notransferase were persistently low (lactate dehydrogenase < 100 U/L, below analyzer range; aspartate

232 id synthase (FASN) and medium chain acyl-CoA dehydrogenase (MCAD) protein within the same cells in cl

233 irectly interacts with medium-chain acyl-CoA dehydrogenase (MCAD).

234 ph, gene expression of the dominant methanol dehydrogenase (MDH) shifts from the lanthanide-dependent

235 MDH2 encodes mitochondrial malate dehydrogenase (MDH), which is essential for the conversi

236 eing co-factors in the XoxF type of methanol dehydrogenase (MDH).

237 somal NADH is reoxidised to NAD(+) by malate dehydrogenase (Mdh3p) and reduction equivalents are tran

238 vided additional gene copies of the pyruvate dehydrogenase multienzyme complex that have evolved into

239 he mass spectra also indicate the isocitrate dehydrogenase mutation status of the tumor via detection

240 relevant in cancer cells bearing isocitrate dehydrogenase mutations.

241 The sodium-dependent NADH dehydrogenase (Na(+)-NQR) is a key component of the resp

242 partially decreased in activity and xanthine dehydrogenase not at all.

243 ing stoichiometry, we hypothesize that NADPH dehydrogenase not only efficiently contributes to ATP pr

244 ssists in the folding of alpha-ketoglutarate dehydrogenase (OGDH), a rate-limiting enzyme in the Kreb

245 y for gauging the ability of a given formate dehydrogenase or other CO2-utilizing enzyme to catalyze

246 radiographic findings with elevated lactate dehydrogenase, or hospitalization for pneumonia with bro

247 fter injury, in line with decreased pyruvate dehydrogenase (PDH) activity, suggesting impairment of t

248 stically, silencing MICU1 activates pyruvate dehydrogenase (PDH) by stimulating the PDPhosphatase-pho

249 's disease (HD) by showing that the pyruvate dehydrogenase (PDH) complex is a promising therapeutic t

250 Resveratrol targets the pyruvate dehydrogenase (PDH) complex, a key mitochondrial gatekee

251 ochondrial bioenergetics, including pyruvate dehydrogenase (PDH) dysfunction, have been described in

252 Pyruvate dehydrogenase (PDH) is the main regulator of the Krebs c

253 Pyruvate dehydrogenase (PDH) plays a well-known metabolic role in

254 phorylation-dependent inhibition of pyruvate dehydrogenase (PDH) within a single day of feeding mice

255 tein II (PfHRP-II) and P. falciparum lactate dehydrogenase (PfLDH) antigens are widely deployed for d

256 Enzymes of the SSP, such as phosphoglycerate dehydrogenase (PHGDH) and phosphoserine aminotransferase

257 ch protein-II (HRPII) and Plasmodium lactate dehydrogenase (pLDH).

258 that a BCL11A peptide can decrease aldehyde dehydrogenase-positive BCSCs and mammosphere formation c

259 Mutations of respiratory NADH dehydrogenases prevent nitrotyrosine formation and abrog

260 proline to glutamate using separate proline dehydrogenase (PRODH) and l-glutamate-gamma-semialdehyde

261 arget genes (i.e., heme oxygenase-1, NAD(P)H dehydrogenase, quinone 1, glutathione reductase, glutama

262 all-trans-retinal is reduced by the retinol dehydrogenase RDH8 to all-trans-retinol in an NADPH-depe

263 ldehyde, and two subunits of NADPH-dependent dehydrogenase reductase 3 (DHRS3), which catalyzes the r

264 In this brief report, dehydrogenase/reductase 9 (DHRS9) is identified as a rob

265 andida parapsilosis is a short-chain alcohol dehydrogenase/reductase.

266 Interestingly, mycobacterial short chain dehydrogenases/reductases (SDRs) within family TIGR03971

267 ct yields of eight other short-chain alcohol dehydrogenases/reductases.

268 The short-chain dehydrogenase-related protein Ayr1 forms an NADPH-regula

269 ukin-1beta [IL-1beta] secretion, and lactate dehydrogenase release) compared to that with the hypha-c

270 for yeast alcohol dehydrogenase and lactate dehydrogenase, respectively, with reaction rates compara

271 CAD5 and Populus tremuloides sinapyl alcohol dehydrogenase, respectively.

272 and paragangliomas associated with succinate dehydrogenase (SDH) deficiency are characterized by high

273 The role of mitochondrial succinate dehydrogenase (SDH) in salicylic acid (SA) signaling was

274 CC1 constitutively associates with succinate dehydrogenase (SDH) subunit A, and amplifies pattern rec

275 of additional genes, including the succinate dehydrogenase (SDH) subunit A, B, C, and D genes.

276 tions in mitochondrial complex II (succinate dehydrogenase; SDH) genes predispose to paraganglioma tu

277 s in cytochrome c oxidase subunit 1 and NADH dehydrogenase subunit 5.

278 at the protein-lipid interface of succinate dehydrogenase subunit B.

279 Isocitrate dehydrogenase subunits Idh1p and Idh2p were assessed bec

280 ne encoding a member of the acyl-CoA oxidase/dehydrogenase superfamily.

281 d1 encodes a novel NADP(+)-dependent glucose dehydrogenase that acts in a pathway with the Idn1 gluco

282 PH oxidase 1 (NOX1), a membrane-bound flavin dehydrogenase that generates O2(), is highly expressed i

283 ate four sp(3) carbons; one flavin-dependent dehydrogenase that is involved in formation of the unsat

284 codes a NADPH-dependent sorbitol-6-phosphate dehydrogenase, the key enzyme for biosynthesis of sorbit

285 ction catalyzed by methylenetetrahydrofolate dehydrogenase, thus allowing plants to cope with oxidati

286 such as Streptococcus gordonii, use pyruvate dehydrogenase to decarboxylate pyruvate.

287 nhibitor against human 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) enzyme (IC50 3.0 nM)

288 use global deletion of 11beta-hydroxysteroid dehydrogenase type 1 normalized Ca(2+) and cAMP response

289 The expression of 11beta hydroxysteroid dehydrogenase type 2 (11beta-HSD2) was age-dependently u

290 selectivity over human 11beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2).

291 f the placental enzyme 11beta-hydroxysteroid dehydrogenase type 2 to inactivate cortisol before it re

292 ,5alpha-diol (OCDO) by 11beta-hydroxysteroid-dehydrogenase-type-2 (11betaHSD2).

293 ins, synthesizes Tyr via plastidic arogenate dehydrogenases (TyrAa /ADH) encoded by two ADH genes (Bv

294 In this study, FAD dependent glucose dehydrogenase was fused to a natural minimal cytochrome

295 A direct electron transfer type glucose dehydrogenase was immobilized onto mesoporous carbon, an

296 m albumin, streptavidin, avidin, and alcohol dehydrogenase were probed using cation-to-anion proton-t

297 cycle (as inferred by flux through pyruvate dehydrogenase), were down-regulated by beta-lapachone tr

298 ydrogenase (5 years, 45%) and normal lactate dehydrogenase with fewer than three organ sites with met

299 ing zwf gene (coding for glucose-6-phosphate dehydrogenase), WX-zwf, produced the highest gamma-PGA c

300 Aedesaegypti has 2 genes encoding xanthine dehydrogenase (XDH).