ライフサイエンスコーパス: deletion mutant

1 s (to minimize polar effects inherent in the deletion mutants).

2 M), but not to the wild-type or a fra island deletion mutant.

3 all five putative PFOR mutants and in a PFL deletion mutant.

4 find that slrA mRNA accumulated in the pnpA-deletion mutant.

5 iratory nitrate reductase activity in a mobA deletion mutant.

6 lysozyme with a higher catalytic rate double deletion mutant.

7 compared with infection with an isogenic hla deletion mutant.

8 A) mutant was stronger than that of the pulM deletion mutant.

9 segment and the attenuated phenotype of NSs deletion mutants.

10 ful, although there have been successes with deletion mutants.

11 ions, we utilized c-di-GMP regulatory enzyme deletion mutants.

12 nt phenotypes in kn1 missense and tm1081(lf) deletion mutants.

13 n and striatal spinogenesis defects of Foxp2-deletion mutants.

14 this surface shell of [PSI+] deposits in the deletion mutants.

15 esis of strain 4295, which consists of three deletion mutants.

16 an isogenic combinatorial collection of NEF deletion mutants.

17 e diploid strains that are homozygous double-deletion mutants.

18 ds to moderate toxicity and the emergence of deletion mutants.

19 Using a double-deletion mutant (12203) of CPXV, we show that direct pri

20 n IgM ligand binding in the cytoplasmic tail-deletion mutant, 2) enhanced cap formation in FcmuR upon

21 nd single-cell studies have shown that mtDNA deletion mutants accumulate in a clonal fashion in vario

22 A ctpJ deletion mutant accumulated Co(2+) , indicating that thi

23 The pvdO deletion mutant accumulates dihydropyoverdine, and this

24 cell function, we analyzed how an endogenous deletion mutant affected Pdx1 expression embryonically a

25 Using a systematic series of deletion mutants (all containing the intact DNA-binding

26 Genetic analysis of DNA methyltransferase deletion mutants also indicated that proper reprogrammin

27 n in the endocarditis model with the new acm deletion mutant although not as great as that previously

28 We constructed an efbA deletion mutant and demonstrated that its virulence was

29 ntly, we generated a nonpolar markerless acm deletion mutant and did not observe a delay in growth.

30 Moreover, the virulence of the fbsC deletion mutant and its ability to colonize the brain we

31 Using an isogenic NalP deletion mutant and NalP complementing strains, we show

32 Analysis of a slr1270 insertion deletion mutant and respective wild-type revealed that t

33 Successful generation of a BbhtrA deletion mutant and restoration by genetic complementati

34 sis genes were still transcribed in the cccA deletion mutant and the quinol oxidase genes (cioAB) wer

35 sed to compare the transcriptomes of an rppH deletion mutant and the wild-type strain incubated at 20

36 Further studies using recA deletion mutants and a cloned rstC gene showed that the

37 111 and C112, in domain B and found that the deletion mutants and a double mutant lacking the C94-C11

38 Using HDAC5 deletion mutants and co-immunoprecipitation studies, we

39 racellular and surface-associated capsule in deletion mutants and complemented strains further implic

40 ng activity we generated GFP-YpkA N-terminal deletion mutants and performed coimmunoprecipitation exp

41 screened Keio collection of Escherichia coli deletion mutants and revealed that deleting genes for re

42 d characterized sncRNA species from two ABI3 deletion mutants and the wild type P. patens that were s

43 ion for the hypomorphic phenotype of the CTR-deletion mutant, and further suggests that Reln mutation

44 several variants of p53 and SUMO1, including deletion mutants, and those with modified sequences cont

45 CKS1 deletion mutants are severely impaired in hyphal growth,

46 ves an essential function in vivo, as bb0405-deletion mutants are unable to transmit from ticks and e

47 ar to the Etl4(lacZ) and Skt(Gt) alleles our deletion mutants are viable and fertile and show only mi

48 ern of yeast Pex11 in all non-essential gene deletion mutants, as well as in temperature-sensitive es

49 etermined that in cells infected with an NS4 deletion mutant (BTV8DeltaNS4), there is increased synth

50 vivo Secretion was impaired in a propeptide-deletion mutant but could be restored by co-expression o

51 ology defects of the actin-like protein MreB deletion mutant by restoration of PBP1 localization.

52 ed cells infected with each of the five VMAP deletion mutants by electron tomography, which is necess

53 analyzed the functionality of several CCBE1 deletion mutants by generating knock-in mice expressing

54 We demonstrate that the deletion mutant can serve as a platform for the isolatio

55 Although this deletion mutant cannot form amyloid, significant amyloid

56 ated to complement the Escherichia coli panD deletion mutant cells, in which panD encoding aspartate

57 icrobeads loaded with CASPR2, but not with a deletion mutant, co-localize with transfected CNTN1, sug

58 sources, such as ORFeome clone libraries and deletion mutant collections, are fundamental tools for e

59 Furthermore, an mrpJ deletion mutant colonized the bladders of mice at signif

60 1 (A/blue-winged teal/MN/993/1980) and an LR deletion mutant, combined with mutational analysis, we s

61 and transcriptome were altered in the sdg8-5 deletion mutant compared to wild type, within the contex

62 The analysis of in frame deletion mutants confirmed the role of a hydroxymethylgl

63 as such was immunologically inert; however, deletion mutant conidia with modified surfaces could act

64 Furthermore, SRSF1 deletion mutants containing the protein RNA-binding doma

65 ential for StAR activity, and the N-terminal deletion mutant continued to interact with VDAC2.

66 nd a monomeric CaMKII oligomerization-domain deletion mutant control.

67 immunoreactivity against a series of PLA2R1 deletion mutants covering the extracellular domains.

68 eq) screening of a pooled collection of gene-deletion mutants cultivated as biofilm and planktonic ce

69 A deletion mutant, DeltaalyA1, grew as well as the wild ty

70 The Clg2p deletion mutant (DeltaClg2p) had altered appressorium fo

71 A M. tuberculosis cytochrome bd oxidase deletion mutant (DeltacydKO) was hyper-susceptible to co

72 The FgSCH9 deletion mutant (DeltaFgSch9) was defective in aerial hy

73 The FgVPS27 deletion mutant (DeltaFgvps27) exhibited a reduction in

74 any effect on virus production; however, the deletion mutant (DeltaG209) showed a very low titer when

75 Here, we synthesize a single deletion mutant, DeltaG25, with the aim of sterically hi

76 ureus (MRSA) strain (MW2), its isogenic graS deletion mutant (DeltagraS strain), a nonameric extracel

77 d with familial frontotemporal dementia, the deletion mutant DeltaK280 and the point mutant P301L.

78 directionally transcribed miRNA locus, and a deletion mutant (Deltamir) lays no eggs and is completel

79 e NDH-2s in Synechocystis, by constructing a deletion mutant (DeltandbC) for a corresponding protein

80 old or more) up- or down-regulated in a scmR deletion mutant (DeltascmR) Metabolically, the DeltascmR

81 ad not previously seen a defect of the TgPL1 deletion mutant (DeltaTgPL1) during acute and early chro

82 isease-susceptible C3H/HeN mice with the arp deletion mutant demonstrated significantly reduced tibio

83 The analysis of deletion mutants demonstrated that the globular domain a

84 in a moderate to severe growth phenotype in deletion mutants, demonstrating a key role for each enzy

85 B. anthracis Ames strain and isogenic toxin deletion mutants derived from the Ames strain to examine

86 The VZV ORF54 deletion mutant described in this study represents the f

87 sues exhibited by mice infected with the arp deletion mutant did not directly correspond to reduced u

88 An Mtb rv0888 deletion mutant did not grow on sphingomyelin as a sole

89 ype 5 (Ad5) E1B 19-kilodalton (E1B 19K) gene deletion mutant did not repress macrophage NF-kappaB act

90 Phenotypic analysis of single and compound deletion mutants did not reveal effects on L1 developmen

91 C. elegans intestinal epithelium, and sdpn-1 deletion mutants display phenotypes indicating a block i

92 AaGPx3 deletion mutants displayed increased sensitivity to H2 O

93 However, lspA3 or lspA4 deletion mutants each exhibited a tan phase variation bi

94 By screening a panel of 39 gene deletion mutants, each lacking a different ubiquitin bin

95 nuclear localization of the PA-X C-terminal deletion mutant enhanced shutoff activity, highlighting

96 The SAM domain deletion mutant, EphA2DeltaS-GFP, also underwent further

97 Deletion mutants exhibited a range of translational phen

98 C-terminal deletion mutants exhibited a reduced tendency to solubil

99 In this study, we found that rcan-1 deletion mutants exhibited cryophilic behavior dependent

100 yl-terminal GPI anchor, while the GPI anchor deletion mutant exhibits dominant negative activity and

101 The sspA deletion mutant exhibits irregular sporulation septation

102 C. albicans sap6 deletion mutants failed to accumulate intracellular zinc

103 osa, and compared the wild-type strains with deletion mutants for crc.

104 ll extremities, whereas in anucleated cells (deletion mutants for mukB), the Tsr clusters are closer

105 n of Tsr clusters at the poles is smaller in deletion mutants for Tol-Pal than in wild-type cells, al

106 ng prompted us to generate a series of Mcl-1 deletion mutants from both the N and C termini of the pr

107 d approach, this method allows us to combine deletion mutants from different experiments and sources.

108 sembly and function in strains in which loop deletion mutant genes are the ONLY: sources of uL4 or uL

109 Individual deletion mutant gra7 or rop18 was partially attenuated f

110 When the deletion mutant grown at 28 degrees C was examined by EM

111 The selD CRISPR deletion mutant had a growth defect in protein-rich medi

112 The FgSSN3 deletion mutant had a nutrient-dependent growth defects

113 ssion of the C-terminal (amino acid 362-396) deletion mutant had no effect.

114 sion electron microscopy studies of two VMAP deletion mutants had suggested retention of connections

115 In corticosteroid-treated mice, a DeltacalA deletion mutant has significantly attenuated virulence r

116 We showed that the deletion mutants have increased binding to human-like re

117 e strategy for Burkholderia, but single-gene-deletion mutants have not provided complete protection.

118 As these deletion mutants impose less inhibition on exocytosis, w

119 stem-like cells using a conditional genetic deletion mutant in a mouse model of platelet-derived gro

120 We constructed a pil3 deletion mutant in a Pil3 overexpressing variant (Pil3+)

121 ptional profiling and functional assays of a deletion mutant in the A. baumannii sensor kinase gene,

122 An ESX-5a deletion mutant in the model system M. marinum backgroun

123 verall, as the first report of targeted gene deletion mutant in U. virens, our results showed that Uv

124 from FMN-hydroquinone to its partners, three deletion mutants in a conserved loop near the FMN were c

125 C. elegans, we utilized the individual gene deletion mutants in E. coli (K12).

126 ecular analyses using defined virulence gene deletion mutants in that lineage as of yet.

127 plied our method to a set of newly generated deletion mutants in the dioecious plant Silene latifolia

128 Four single deletion mutants in ttn.2 or ttn.1 resulted in four phen

129 he expression of a CD81 carboxy (C)-terminal deletion mutant, increases cellular dNTP content and HIV

130 the most highly upregulated gene in the nmoR deletion mutant, independently of MexT.

131 production of 128 proteins in the oxyR gene deletion mutant, indicating its global regulatory role i

132 phenotype is similar to that of MGAS5005 sse deletion mutants, indicating that the enzymatic activity

133 An E3 deletion mutant induced protein kinase R (PKR) and eukar

134 Infection of Swiss cells with an EHEC espW deletion mutant induces a cell shrinkage phenotype that

135 We discovered that the terminator deletion mutant is highly resistant to neutrophil-mediat

136 Regulation of a CLH-3b AD deletion mutant is reconstituted by intracellular perfus

137 An mbfA deletion mutant is severely defective in iron export act

138 h DiGeorge syndrome and in experimental Tbx1 deletion mutants is associated with thymus aplasia or hy

139 An alphaS deletion mutant lacking amino-acid residues 71-82 binds

140 red in two independent cerk1 null mutants; a deletion mutant lacking D14L, and with D14L complemented

141 We investigated a deletion mutant lacking only this alpha-helix in stable

142 We then constructed two deletion mutants lacking C-terminal regions and mutants

143 s less constrained, whereas in the D219/E220 deletion mutant, little orientational preference was obs

144 f Mafa(-/-) and pancreas-specific Mafa(panc) deletion mutant mice demonstrated a primary role for Maf

145 then crossed these animals with the NDL (Neu DeLetion mutant) model of ErbB2-induced mammary tumorige

146 The MoSYN8 deletion mutant (Mosyn8) mutant exhibits defects in endo

147 he BERosome complex, as observed for a NEIL1 deletion mutant (N311) lacking the CTD, not only inhibit

148 ions, two without the N66S mutation, and one deletion mutant not encoding the PB1-F2 protein.

149 We report that an htaA deletion mutant of C. diphtheriae strain 1737 is unable

150 We therefore generated a cytoplasmic deletion mutant of CD27 (CD27-trunc) to study the role o

151 A defined deletion mutant of cysE was attenuated in C57BL/6 wild-t

152 ransgenic plants expressing the F-box domain deletion mutant of FOF2 (FOF2DeltaF), or double loss of

153 Here we created a deletion mutant of gene all3922 encoding isoaspartyl dip

154 endotoxicity and CAMP resistance of a double deletion mutant of lpxE-eptA was similar to that of a si

155 Herein, a deletion mutant of MAB_4780, encoding a dehydratase, dis

156 h ICP8 and BALF2, a 60-amino-acid C-terminal deletion mutant of Orf6 was generated, and the protein w

157 A quadruple deletion mutant of PpCSP1 and three closely related PpCS

158 Moreover, a deletion mutant of rovA, previously shown to be moderate

159 with PTEN for binding to DLG-1, unlike a PBM deletion mutant of Tax1.

160 in the absence of ligands, and a well folded deletion mutant of the Bacillus stearothermophilus enzym

161 a role in Ca(2+) homeostasis, we studied the deletion mutant of the HTT ortholog in the model develop

162 To confirm this, we created a ccpA deletion mutant of TX82, which also exhibited a slight d

163 We constructed an fnr deletion mutant of UPEC CFT073 and compared it to the wi

164 As expected, the A6 deletion mutant of VACV failed to replicate in noncomple

165 ed metabolomics analysis of an S. cerevisiae deletion mutant of YDR109C revealed ribulose as one of t

166 Deletion mutants of Agrobacterium lacking monoglucosyl d

167 pproach to produce a library of >9000 random deletion mutants of an artificial RNA ligase enzyme repr

168 different perturbations (e.g., antibiotics, deletion mutants of assembly factors, oxidative stress,

169 We show that spoIIQ or spoIIIAH deletion mutants of C. difficile result in anomalous eng

170 Single-deletion mutants of chtA or chtC use Hb-Hp iron in a man

171 lting in reduced nucleosome-barrier, such as deletion mutants of histones H3/H4 themselves and the ge

172 characteristics, and produced isogenic gene deletion mutants of important CA-MRSA virulence determin

173 In an application to data from deletion mutants of kinases and phosphatases in S. cerev

174 We examined deletion mutants of luxO, opaR, and aphA for in vivo fit

175 By screening a panel of deletion mutants of mouse cytomegalovirus (MCMV) a mutan

176 A recent study by Laplante et al.[3], using deletion mutants of myp2 and myo51 and the mis-sense mut

177 tion of the mammalian host by using unmarked deletion mutants of the F. tularensis live vaccine strai

178 Deletion mutants of the seven genes within one LSR (G-LS

179 el trafficking to the membrane, we generated deletion mutants of the TRPC4 channel.

180 gical changes and altered gene expression in deletion mutants of two N-myristoylated PPs.

181 Deletion mutants of unc-68, and in particular the point

182 ues the viability of a S. cerevisiae cofilin deletion mutant only when the stiffness cation site is s

183 itopes with fibroblasts infected with a UL11 deletion mutant or the parental strain revealed that und

184 The deletion mutant phenotype was reproduced by using transf

185 he mutant OGTs that did not fully rescue the deletion mutant phenotypes had reduced or no activity.

186 atory imbalances that are not uncovered from deletion-mutant phenotyping.

187 paring parental B. pertussis to an rseA gene deletion mutant (PM18), we sought to characterize the ro

188 Most interestingly, the deletion mutant possessed a higher thermal stability and

189 We tested several candidate miRNA-deletion mutants post gamma-irradiation and identified c

190 ygen-dependent alginate synthesis inhibitor) deletion mutant produced alginate also in the presence o

191 showed that inoculation with a DeltaprrF1,2 deletion mutant protects against future challenge with w

192 f PE in the phosphatidylserine decarboxylase deletion mutant (psd1Delta) cause decreased respiration,

193 In this study, we showed that the Fgsrp1 deletion mutant rarely produced conidia and caused only

194 on of the NCR169 gene into the dnf7-2/NCR169 deletion mutant restored symbiotic nitrogen fixation.

195 in no flagellar formation although this FliI deletion mutant retained 40% of the ATPase activity, sug

196 Interestingly, the NTR deletion mutant retained 61.5% and 19.5% enzymatic activ

197 alysis of peptidoglycan sacculi from an rlpA deletion mutant revealed increased tetra and hexasacchar

198 Phenotypic analysis of TF deletion mutants revealed complex relationships among vi

199 Proteomic analysis of efp and poxA deletion mutants revealed decreased levels of several vi

200 plementation experiments performed with PstP deletion mutants revealed marginally compromised surviva

201 Studies using the 1.9-kb SK1 promoter and deletion mutants revealed that basal and FGF2-stimulated

202 , a nonbiased screen of transcription factor deletion mutants revealed that the phosphate-responsive

203 ing site within the APLP1 E2 domain as APLP1 deletion mutants revealed.

204 holoenzyme containing an RIIbeta C-terminal deletion mutant (RIIbeta(1-280)), which is missing the C

205 h cDNA clone of SL-CoV WIV1 (rWIV1), an ORFX deletion mutant (rWIV1-DeltaX), and a green fluorescent

206 capsule-switching mutant and with a capsule deletion mutant showed that the capsule protected S. mit

207 e corresponding C. elegans clec-49 and fat-3 deletion mutants showed delayed biofilm formation and ab

208 Analysis of RGB-derived K3 and K5 deletion mutants showed that while the K5-mediated downr

209 of CSQ1 or a C-terminal (amino acid 388-396) deletion mutant significantly promoted the association o

210 ion between SK or its COOH-terminal Lys(414) deletion mutant (SKDeltaK414) and active site-labeled [L

211 A MakatG1 deletion mutant strain (DeltaMakatG1) showed decreased c

212 An ibeA deletion mutant strain (NRG857cDeltaibeA) was constructe

213 e, a yeast (Saccharomyces cerevisiae) SEIPIN deletion mutant strain and a plant (Nicotiana benthamian

214 In this study, we determined that an rpoE deletion mutant strain BHM2578 compared to the wild type

215 s of a wild-type strain and an isogenic fabT deletion mutant strain found that between 3.7 and 28.5%

216 strain; in situ reconstitution of fnm in the deletion mutant strain restored adherence.

217 Here we generate a new deletion mutant strain, CVS-N2c(DeltaG), and examine its

218 h more resistant to oxidants than a catalase-deletion mutant strain.

219 ing, mass spectrometry, and the use of a p13 deletion mutant strain.

220 m were significantly upregulated in the fabT deletion mutant strain.

221 Individual DeltatrxA and DeltatrxC deletion mutant strains each show a greater abundance of

222 Notably, deletion mutant strains were more resistant to ciproflox

223 surface in both the E. coli parent and aceE deletion mutant strains.

224 s of lipid A isolated from the corresponding deletion mutant strains.

225 nalyses of ert-m and ant1 single- and double-deletion mutants suggest Ant1 as a closely linked gene e

226 ce that was comparable to that in the bb0238 deletion mutant, suggesting that BB0238 may contain a fu

227 examination of the inferred fitness of gene deletion mutants suggests that secondary replicons evolv

228 geneity was more pronounced in the D219/E220 deletion mutant than in the E220A mutant, indicating tha

229 ion of wild-type Pdcd4 and Pdcd4(157-469), a deletion mutant that binds to translation initiation fac

230 tive PARP6 mutant, or a cysteine-rich domain deletion mutant that has significantly reduced catalytic

231 himeric dimers of aS (syn-syn) and by the aS deletion mutant that lacks the C-terminus, i.e., aS (1-9

232 We identified 56 diverse E. coli deletion mutants that enhance dauer formation in an insu

233 zing ability: nonmotile E. coli MG1655 flhDC deletion mutants that grew 15% faster in vitro in mouse

234 ave successfully generated a B. hermsii fhbA deletion mutant (the B. hermsii YORDeltafhbA strain) thr

235 Also in deletion mutants, the distribution of Tsr clusters diffe

236 Here, we constructed a C. burnetii pmrA deletion mutant to directly probe PmrA-mediated gene reg

237 The failure of the AcrB DN beta-hairpin deletion mutant to engage with TolC leads to the drug hy

238 These six basic amino acids enabled a PA deletion mutant to suppress protein expression at a leve

239 eficient EBOV VP40 double PTAP/PPEY L-domain deletion mutant to wild-type levels.

240 We constructed relA and relA spoT deletion mutants to assess the contribution of (p)ppGpp

241 is study, we used a set of androgen receptor deletion mutants to identify the microtubule-binding dom

242 ival, as determined by the inability of vapA deletion mutants to replicate in host macrophages.

243 Subsequently, we subjected deletion mutants to suboptimal temperatures that are kno

244 nes that are differentially expressed in the deletion mutant under both culture conditions conformed

245 tion of ace to be virtually absent in a grvR deletion mutant under the conditions that increase ace e

246 ALS3 and integrated into the ALS3 locus of a deletion mutant, under control of the native ALS3 promot

247 The NMR structure revealed that this deletion mutant undergoes a dramatic structural change c

248 fined using a series of alanine scanning and deletion mutant variants.

249 I2 and allowed construction of the VACV I2L deletion mutant vDeltaI2.

250 optosis induced by infection with an E1B 19K deletion mutant virus did not repress macrophage proinfl

251 density and the infectivity of a class II IN deletion mutant virus.

252 -type L. lactis strain KF147 but not an xylA deletion mutant was able to grow using xylose as the sol

253 id of transport activity, but remarkably the deletion mutant was active, as were mutants obtained by

254 Furthermore, the ccpA deletion mutant was attenuated (P = 0.0024) in a mixed-i

255 An OGT deletion mutant was created and found to exhibit several

256 baumannii response to zinc limitation, a zur deletion mutant was generated, and transcriptional chang

257 One Uvhog1 deletion mutant was identified after screening over 600

258 A pglA deletion mutant was impaired in both pathogenesis and gu

259 A lipA lipB deletion mutant was more sensitive than the wild-type pa

260 The amd1 deletion mutant was normal in growth and conidiation but

261 A K0326Y QPM deletion mutant was null for the 27- and 50-kD gamma-zei

262 When the CpGV-M deletion mutant was repaired with pe38 from isolate CpGV

263 We found that an ompU deletion mutant was sensitive to bile salt stress but re

264 The asp f3 deletion mutant was sensitive to ROS, and this phenotype

265 Furthermore, we showed that each deletion mutant was significantly attenuated in comparis

266 Importantly, we showed that pil3 deletion mutant was unable to colonize mice colon as com

267 GABA-induced transport currents by all three deletion mutants was diminished, and the charge-to-flux

268 n, and that the survival of prophenoloxidase-deletion mutants was impaired when fed several plant phe

269 Using a domain deletion mutant we demonstrated the involvement of the C

270 negatively charged residues of the D219/E220 deletion mutant, we measured more unfavorable entropic a

271 yces cerevisiae) vps23Delta bro1Delta double-deletion mutant, we showed that the Vps23p ESCRT-I prote

272 dy, using a variety of chimeric proteins and deletion mutants, we define the features necessary for a

273 protein-tagged components or from different deletion mutants, we determined the molecular architectu

274 Using a variety of chimeras and deletion mutants, we found that in addition to a functio

275 By coexpression of the wild-type TRPC4 with deletion mutants, we found that the 23-29 amino acids of

276 y characterizing a series of PA-X C-terminal deletion mutants, we found that the first 9 amino acids

277 chemical and crystallographic analysis of HD deletion mutants, we show that the HD is an autoinhibito

278 Cells of a porV deletion mutant were deficient in chitin utilization and

279 between full-length ORF6 and the C-terminal deletion mutant were observed with the short DNAs, bindi

280 hese chromosomal mutations as well as a pslG deletion mutant were still capable of forming Psl biofil

281 ominently increased replication of the SPI-1 deletion mutant were subjected to a secondary screen.

282 We found that all deletion mutants were capable of forming caffeine- and r

283 bpsl2248, tex, rpiR, bpsl1728, and bpss1528 deletion mutants were constructed from the wild-type str

284 ine how eIF4G recruits the mRNA, three eIF4G deletion mutants were constructed: (i) eIF4G601-1196, co

285 The hptA, hptRS, and uhpT markerless deletion mutants were generated by an allelic replacemen

286 Both deletion mutants were much more sensitive to O2-mediated

287 Capsule deletion mutants were not lysed by this phage, suggestin

288 The N1, N2, N4, and N5 deletion mutants were significantly impaired in T4P-medi

289 Twelve single gene deletion mutants were under selection in this assay, and

290 Isogenic P1 deletion mutants were used to reconstitute the previousl

291 interaction and functional analyses of XND1 deletion mutants were used to test the importance of RBR

292 NB-B), and here, we characterize a recurrent deletion mutant where the last 14 residues are missing.

293 We have generated a DeltaPpcmt deletion mutant which demonstrated that PpCMT is essenti

294 We generated a dpr deletion mutant which displayed normal early-log-phase a

295 n of P. patens PpMET we generated DeltaPpmet deletion mutant which lost (m)CG and unexpectedly (m)CCG

296 ortant for virulence, we created a Deltacps1 deletion mutant which was unable to cause disease in thr

297 not essential for virulence, because the Mip deletion mutant, which failed to form dimers, was still

298 We identified two HSV-1 ICP27 amino-terminal deletion mutants with a similar release defect.

299 A comparison of the binding of eIF4G deletion mutants with BTEs containing mutations showed a

300 into a pool of 4653 homozygous diploid yeast deletion mutants with unique barcode sequences, followed