ライフサイエンスコーパス: delivery system

1 sideration in designing a MWNT-based vaccine delivery system.

2 ate the promise of a gel depot as an IP drug delivery system.

3 nal NIR laser diode, is developed as a power delivery system.

4 nt of lung cancer requires an efficient drug delivery system.

5 a platform to develop novel anti-cancer drug delivery system.

6 phores enhances the efficiency of this smart delivery system.

7 California, a large, integrated health care delivery system.

8 dissolvable microstructure-based transdermal delivery system.

9 g., Orbitrap) using a chip-based nESI sample delivery system.

10 rticipants who were members of a health-care delivery system.

11 orans cells g(-1) sediment with 1.5% AC as a delivery system.

12 n, and lower actual payments received by the delivery system.

13 e a promising multifunctional antitumor drug delivery system.

14 al, emphasized and investigated in each drug delivery system.

15 ysicochemical properties for a targeted drug delivery system.

16 leaflets that is placed using a transapical delivery system.

17 kforce through an innovative community-based delivery system.

18 e Northern California integrated health care delivery system.

19 -targeting glucan microparticle (GP) vaccine delivery system.

20 splatin was infused into the brain without a delivery system.

21 d toward the development of implantable drug-delivery systems.

22 logy, nanomedicine, and many nano-sized drug delivery systems.

23 em, researchers are investigating novel drug delivery systems.

24 odistribution and performance of particulate delivery systems.

25 , ranging from processed foods to novel drug delivery systems.

26 ecules is crucial for improving current drug-delivery systems.

27 ellular uptake and nuclear targeting of drug delivery systems.

28 e promise is hampered by a lack of desirable delivery systems.

29 ess is limited by the lack of robust in vivo delivery systems.

30 s an antioxidant may be the most suitable as delivery systems.

31 ferent cancer cell lines using two different delivery systems.

32 icability of dSTORM for use in studying drug delivery systems.

33 oups for conjugation to antibodies and other delivery systems.

34 and recent progress of combined NO and drug delivery systems.

35 emistry of pharmaceuticals in nanosized drug-delivery systems.

36 ral drug delivery systems, and biologic drug delivery systems.

37 onstrated herein are key for successful drug delivery systems.

38 will aid the optimization of local antibody delivery systems.

39 red for endocytosis and transcytosis of drug delivery systems.

40 placed directly in the brain within standard delivery systems.

41 y for the creation of putative, targeted-VLP delivery systems.

42 potential for developing the efficient drug delivery systems.

43 s to manage safety risks and plan safer care delivery systems.

44 d 382 articles describing viral and nonviral delivery systems.

45 ible applications in drug synthesis and drug delivery systems.

46 earch and development led to commercial drug delivery systems.

47 e when combined with molecular-targeted drug delivery systems.

48 major shortcoming in plasmon actuated cargo delivery systems.

49 cision support, with accompanying changes in delivery systems.

50 ease of drug molecules represent intelligent delivery systems.

51 ing from waterborne coatings to drug-carrier-delivery systems.

52 ign of the next-generation of nanoscale drug delivery systems.

53 h information, (2) navigating in health care delivery system, (3) interactions during health care enc

54 ensively describes various NPs-mediated drug delivery systems according to different NPs species.

55 cluded members of a Seattle-area health care delivery system (ACT), priests and nuns living in orders

56 ology for the development of anti-viral RNAi delivery systems against influenza virus infection.

57 Balloon-based drug delivery systems allow localized application of drugs to

58 sue that is 14-F compatible with a motorized delivery system allowing for repositionability.

59 The drug delivery system also comprises a semi-automatic reconsti

60 A functionalized nanohydrogel siRNA delivery system and a mouse model of serous ovarian canc

61 ght to develop a dry-coated microneedle (MN) delivery system and combine it with topical steroid to m

62 observed for those cells incubated with the delivery system and exposed to light irradiation compare

63 elationship between the emerging health care delivery system and residency training, highlighting iss

64 ces the immunogenicity of protein cage-based delivery systems and active targeting ligands can be att

65 xt, we review recent development of PTX drug delivery systems and analyze the design principles under

66 the development of magnetically guided drug delivery systems and its potential on efficient anticanc

67 sulated within low-energy nanoemulsion-based delivery systems and protected against degradation.

68 g the quality and performance of transdermal delivery systems and topical patches (collectively, TDS)

69 eated within KSPC, an integrated health care delivery system, and died between 2001 and 2010 before a

70 h care utilization measures, payments to the delivery system, and program investment costs.

71 gen delivery to APCs as an efficient vaccine delivery system, and simultaneously, activated Toll-Like

72 oding an Ag, and formulated with a synthetic delivery system, and they induce broad-based immune resp

73 ess that has been made in drug therapies and delivery systems, and also cell-based and tissue enginee

74 ug delivery for localized therapy, oral drug delivery systems, and biologic drug delivery systems.

75 ivery of bioactive moieties, anticancer drug delivery systems, and theranostics (i.e., real-time moni

76 and accumulation of nanoparticle-based drug delivery systems are highly dependent on the particle si

77 New drug delivery systems are highly needed in research and clini

78 On-demand drug delivery systems are highly promising to control the tim

79 Tumor-targeted drug delivery systems are promising for their advantages in e

80 Drug delivery systems are required for drug targeting to avoi

81 mmed from different cell types and different delivery systems, as well as human embryonic stem cell (

82 hod for preclinical assessment of novel drug delivery systems at therapeutic doses in models of disea

83 here a one pot RNA production, packaging and delivery system based on bacteriophage Qbeta.

84 Herein we developed a nanoparticle drug delivery system based on the assembly of surface-modifie

85 elopment of a new glucose-responsive insulin delivery system based on the potential interaction betwe

86 ot process led to be the most favorable drug delivery system based on the release kinetics pointing t

87 es report for the first time an ASO and RNAi delivery system based upon protein toxin architecture th

88 The development of drug delivery systems based on well-defined polymer nanostruc

89 A "relay drug delivery" system based on two distinct modules, which is

90 aterial in many applications, including drug-delivery systems, bone-graft fillers and medical devices

91 affects health, 4) an integrated health-care delivery system buffers patients from the effects of the

92 nanosponges not only as a dual release drug delivery system but also enabling a regulated metabolism

93 The implantable drug-delivery system can be powered with a TENG device rotate

94 stood so that the future development of drug delivery systems can be accelerated and prolific again.

95 the pH differences in the body, various drug delivery systems can be designed by utilizing smart biop

96 sing multiple bioactive factors in different delivery systems can develop new strategies for improvin

97 son system is a highly active non-viral gene delivery system capable of integrating defined DNA segme

98 clude skeletal tissues and biominerals, drug delivery systems, catalysts, sensors, separation media,

99 The present study reports a drug delivery system comprising nanostructured lipid carrier

100 nd optimization of a hybrid-dual particulate delivery system consisting of two natural biomaterials,

101 ble silicon-based probe with a compact light delivery system, consisting of silicon nitride waveguide

102 The composite drug delivery system consists of highly-textured superhydroph

103 The use of such a delivery system could, following further development, ha

104 t immune functions, and accumulation of drug delivery systems could have significant implications for

105 er, we constructed photoresponsive dual drug delivery system (DDS) to release two different anticance

106 Advanced drug delivery systems (DDS) enhance treatment efficacy of dif

107 importance as site-specific controlled drug delivery systems (DDSs) and has encouraged their rapid d

108 Among drug delivery systems (DDSs), smart nanocarriers that respond

109 Taken together, the co-delivery system demonstrated great promise as potential

110 The delivery system developed could be employed to create no

111 Systemically injected drug delivery systems distribute into various organs and tiss

112 In summary, tumor-targeted and synchronized delivery system elicits enhanced anticancer effects and

113 review, we summarize the existing CPP-based delivery system, emerging landscape of CPP application i

114 Here, we report an mRNA delivery system employing graphene oxide (GO)-polyethyle

115 unctive use of 0.5% AZM as a controlled drug delivery system enhances the clinical outcome.

116 his formulation was superior to all particle delivery systems evaluated and maintained its bioactivit

117 characterise a novel micro-needle array (MA) delivery system fabricated to deliver a live recombinant

118 However, current in vivo mRNA delivery systems fail to transfect B lymphocytes and ins

119 We have developed a liposomal delivery system for a prodrug of vinblastine (CPD100) wh

120 ntially be used to design an efficient siRNA delivery system for asthma therapy.

121 further studies on developing exosome-based delivery system for disease treatment.

122 developed an effective tumor-targeting siRNA delivery system for in vivo application.

123 PEGylation of paclitaxel offers a potential delivery system for inhalation with improved anti-cancer

124 at fungal pathogens can provide an effective delivery system for mosquitocidal or malariacidal biomol

125 me-peptide-siRNA nanoparticle as a non-viral delivery system for MRTF-B siRNA in conjunctival fibrosi

126 est that PLGA nanoparticles can be used as a delivery system for phenolic compounds at lower levels t

127 Therefore, FA-3LM could become a promising delivery system for receptor-mediated drug or gene deliv

128 tty acids to CGKRK could create an efficient delivery system for siRNA silencing specifically in tumo

129 We present a drug delivery system for the GI tract based on coating standa

130 s have been proposed as a minimally invasive delivery system for the intradermal administration of nu

131 ly described a novel constitutive endogenous delivery system for the translocation of nanomineral-ant

132 desired characteristics of an effective drug delivery system for the treatment of pulmonary diseases

133 ave shown promise as a sustained, local drug delivery system for therapeutics in a variety of applica

134 d to discover and validate a novel nano-oral delivery system for this promising anticancer agent.

135 on for the rational design of emulsion-based delivery systems for a lipophilic natural dye and nutrac

136 w possibilities to construct multifunctional delivery systems for a wide range of applications.

137 These findings are important for designing delivery systems for commercial production of encapsulat

138 sed nanocarriers can serve as bioactive drug delivery systems for effective treatment of lysosomal st

139 of metal-organic frameworks (MOFs) as novel delivery systems for encapsulation and controlled releas

140 on in vivo validation of such magnetic drug delivery systems for first time, we selected cisplatin a

141 relevant applications ranging from targeted delivery systems for insoluble drugs, bioactive substrat

142 There have been significant developments in delivery systems for mucosal vaccination.

143 for antibody-drug conjugates and other drug delivery systems for personalized targeted cancer chemot

144 s non-covalent interaction in nanoscale drug delivery systems for pharmaceutical agents, including sm

145 lactoglobulin (BLG) was exploited to develop delivery systems for quercetin.

146 loads for antibody-drug conjugates and other delivery systems for targeted and personalized cancer ch

147 very, and tissue engineering.The use of drug delivery systems for the gastrointestinal tract has been

148 ically nanoparticles and nanofibers, as drug delivery systems for topical and transdermal application

149 Nanoparticulate delivery systems for vaccine adjuvants, designed to enha

150 Nanotechnology- based delivery systems grabbed tremendous attention for delive

151 A chitosan-based microsphere delivery system has been fabricated for controlled relea

152 No periadventitial drug delivery system has reached clinical application.

153 The adeno-associated virus (AAV) vector gene delivery system has shown promise in several clinical tr

154 ntial for use of polymers in controlled drug delivery systems has been long recognized.

155 ve compounds using plant-derived proteins as delivery systems has received increasing interest.

156 ess, so far imaging-guided photothermal drug-delivery systems have been developed with limited succes

157 Numerous local drug delivery systems have been studied to overcome the short

158 For more than 60years drug delivery systems have produced numerous controlled relea

159 erties of these novel nanoconstructs as drug-delivery systems highlight the potential of this approac

160 reasingly attracted to exploit those as drug delivery systems, highly efficient photothermal modaliti

161 Integrating DNA delivery systems hold promise for many applications incl

162 ty of DIM-14 via self-emulsifying drug (SED) delivery system in dogs and to evaluate pharmacodynamic

163 model demonstrated the effectiveness of this delivery system in improving cardiac function, ventricul

164 ers Medical Group, an integrated health care delivery system in Minnesota, at any time between 2007 a

165 n California, a large integrated health care delivery system in northern California.

166 sed as a novel and effective target for drug delivery system in tumor cells using chemically modified

167 tegy for engineering stimuli-responsive drug delivery systems in a bioinspired and synergistic fashio

168 Nanoparticles are emerging as targeted drug delivery systems in chronic inflammatory disorders.

169 es to overcome these challenges include drug delivery systems in conjunction with other chemical and

170 can be used to monitor accumulation of drug delivery systems in preclinical and clinical studies.

171 dge of the role of insurance and health-care delivery systems in protecting the health of diabetic pa

172 apy to [60]fullerene nanoparticle-based drug delivery systems in targeting the micro-vasculature and

173 as the most varied health care financing and delivery systems in the world, it has become an especial

174 ds used to design and evaluate targeted drug delivery systems in vivo.

175 al parameter for their potential use as drug delivery systems in vivo.

176 ed in the successful design of balloon-based delivery systems, including drug release kinetics, matri

177 two-component, two-step, pre-targeting drug delivery system integrated with image guidance to circum

178 e and easy method for localising particulate delivery systems into dissolving MN.

179 MVDS is that the polymer used to prepare the delivery system, Inulin Acetate (InAc), activates the in

180 This novel oral GLP1 delivery system is an attractive alternative to treat la

181 The delivery system is based on microparticles of PolyActive

182 Drug-coated balloon delivery system is characterized by a rapid drug transfe

183 This novel drug delivery system is comprised of a thermoresponsive hydro

184 The proposed nanoparticulate drug-delivery system is designed for the oral administration

185 Therefore, the development of a targeted GEM delivery system is highly desired.

186 Developing an advanced nucleic acid drug delivery system is of great significance in order to ach

187 r (TENG)-based self-powered implantable drug-delivery system is presented.

188 Thus, the microstructural evolution of lipid delivery systems is a crucial factor in lipid digestion

189 mical changes on the microstructure of lipid delivery systems is challenging.

190 To prolong their efficacies, the use of delivery systems is essential.

191 on and enable rational design of lipid-based delivery systems is presented.

192 s, however, lack of safe and efficient siRNA delivery systems limits the application of siRNA as a th

193 pported with a noninvasive positive pressure delivery systems may be feasible alternative to standard

194 ydrophobic molecules into nanoemulsion based-delivery systems may therefore enable their activities t

195 testing of a novel Exo-GNP-based therapeutic delivery system -'nanosomes'- for lung cancer therapy.

196 In particular, nanoparticle-based drug delivery systems not only facilitate the delivery of mul

197 ieties expressed on MM cells to nanoparticle delivery systems (NPs), which have failed mainly due to

198 ple and practical way to produce an adequate delivery system of bioactive compounds of saffron by pro

199 n assist in designing the proper water-based delivery system of GEO for application in food preservat

200 The oral delivery system of insulin designed by us showed a long-

201 Here, we designed a novel pulmonary delivery system of siRNA, transferrin-polyethylenimine (

202 Effective targeted drug delivery systems often rely on external stimuli to effec

203 en utilized in developing polymer-based drug delivery systems over the past 10years.

204 nt birch pollen allergen Bet v 1 using patch delivery system (PDS) with or without heat-labile toxin

205 As smaller delivery systems permit TF-TAVR in many of these patient

206 apors using a pneumatically modulated liquid delivery system (PMLDS) coupled to a polytetrafluoroethy

207 particulate based pathogen-mimicking vaccine delivery system (PMVDS) to target antigen-presenting-cel

208 g therapy in a large, integrated health care delivery system population was identified in 2008 and fo

209 produce biofunctional nanovesicle-based drug delivery systems potentially applied to treat various di

210 The two-agent delivery system presented here possesses notable biophys

211 cancer is the development of effective drug delivery systems, primarily nanoparticles.

212 tion of inhaled gene therapy, including gene delivery systems, primary physiological barriers and str

213 an invasive strategy, implementation of care delivery systems prioritising immediate revascularisatio

214 s, including actuators, motion sensors, drug delivery systems, projection displays, etc.

215 Nanoparticle-based drug delivery systems provide a highly promising approach for

216 vely, this newly developed nanoparticle oral delivery system provides a basis for evaluation of SP141

217 In this co-delivery system, PTX was covalently conjugated to poly (

218 art Association on the impact of payment and delivery system reform, as well as how the American Hear

219 lement the Health Insurance Marketplaces and delivery system reform, increasing federal financial ass

220 rt Association's Expert Panel on Payment and Delivery System Reform, serves to offer support and dire

221 As such, delivery system reforms focused on building teamwork may

222 orms, cost and affordability provisions, and delivery-system reforms.

223 MCTS have also been widely exploited in drug delivery system research for comprehensive study of drug

224 to their applications in tumor-targeted drug delivery system research.

225 Permanente Northern California, a healthcare delivery system serving 3.9 million members.

226 pment of plant virus-based materials as drug delivery systems; specifically, this work focuses on the

227 s an urgent need to expand the surgical care delivery system starting with the district-level hospita

228 e due to current shortcomings in phage-based delivery systems such as inefficient delivery, narrow ho

229 fficking of biomolecules and nanoparticulate delivery systems such as polyplexes.

230 Current viral delivery systems such as retro- and adenoviruses suffer

231 lated into a targeted polymeric micelle nano-delivery system (SUNb-PM), working in a synergistic mann

232 hibitor conjugates with folic acid as a drug-delivery system targeting folate receptors.

233 from two, matrix-type, nicotine transdermal delivery systems (TDS).

234 sent a novel two tier platform; i) a peptide delivery system, termed RALA, that is able to wrap the D

235 to pericardial patches are a novel composite delivery system that allows sustained site-specific deli

236 Herein, we report an oral insulin delivery system that can overcome the above-mentioned pr

237 of this study was to develop a topical siRNA delivery system that can permeate through the stratum co

238 e report on an effective brain-targeted drug delivery system that combines a robust red blood cell me

239 resent an efficient and safe non-viral siRNA delivery system that could be used to prevent fibrosis a

240 manuscript, we present a novel micellar drug delivery system that is not only capable of releasing it

241 n D1 therapy in MCL and present a novel RNAi delivery system that opens new therapeutic opportunities

242 to encapsulate DNA, and their application as delivery system that specifically targets activated macr

243 our present study, we report a peptide-based delivery system that utilizes enzyme assisted cleavable

244 ment of SIgA alongside systemic immunity and delivery systems that improve vaccine delivery to the ta

245 d balance function is likely to require gene delivery systems that target auditory and vestibular sen

246 disease progression, and development of new delivery systems that target such diseases.

247 escribe our experience with AAV viral vector delivery system, that allows us to optimize and monitor

248 We engineered an in vivo delivery system to assemble scaffolds by injection of a

249 ere we present a targeted, non-invasive drug delivery system to decrease inflammation in an osteoarth

250 eate hydrogels, a type of soluble biopolymer delivery system to encapsulate flavored nanoemulsions th

251 In this study, we designed an adenoviral delivery system to genetically modify hMPCs to express a

252 ndicated that nanoemulsions can be used as a delivery system to improve the cellular uptake of lutein

253 ls engage a highly coordinated Cu uptake and delivery system to prevent the accumulation of toxic Cu

254 evelopment of a sustainable intraocular drug delivery system to protect RGCs, which may be applicable

255 the structure and function of the metabolite delivery system to the outer retina may be investigated

256 ndings suggest S/O/W emulsions are potential delivery systems to incorporate lactase in milk products

257 mportance in translating liposome-based drug delivery systems to other molecules and cargo.

258 ical applications ranging from advanced drug delivery systems to tissue engineering.

259 re promising candidates for long-acting drug delivery systems to treat chronic diseases.

260 ntation of these new models will necessitate delivery system transformation and will actively involve

261 e demonstrate that a novel transvaginal drug delivery system (TVDS) is capable of delivering peptide

262 e vinyl acetate (EVA) ring transvaginal drug delivery system (TVDS).

263 candidates in applications ranging from drug delivery systems, up to artificial organelles, or active

264 the current study, we designed sequential co-delivery system using a near-infrared-radiation (NIR) re

265 raction, we created a nanovesicle-based drug delivery system using nitrogen cavitation which rapidly

266 of GAG, we created an in situ gelling rectal delivery system using silk-elastinlike protein polymers

267 to develop an RGC-targeted intraocular drug delivery system using unimolecular micelle nanoparticles

268 Targeted drug delivery systems using nanoparticle nanocarriers offer r

269 ically viable and 'bottom-up' self-assembled delivery systems usually substitute one solubilizing exc

270 We propose an effective cell delivery system utilizing appropriate vascularization at

271 In addition, a dedicated liquid nitrogen delivery system was developed.

272 Controlled drug release from the delivery system was mediated by physicochemical changes

273 The percentage of drug released from the delivery system was significantly greater (24%) when exp

274 The magnetically guided drug delivery system was successfully developed by utilizing

275 Development of new controlled drug delivery systems was very productive during the period 1

276 al registry at 2 large integrated healthcare delivery systems, we compared 883 patients undergoing PV

277 owth factor (VEGF) biologic and a compatible delivery system were co-evaluated for protection against

278 Payments to the delivery system were lower in the TBC group vs the TPM g

279 The peptide-based delivery systems were non-toxic to the RPE cells, chemic

280 evel of anise oil as potential antimicrobial delivery systems were prepared.

281 her in mice receiving the targeted nano-drug delivery system when compared to non-targeted system or

282 ease processes, especially for site-specific delivery systems where localized targeting of particles

283 er to enrich allicin in a functional food, a delivery system which stabilises the compound and masks

284 The development of anticancer drug delivery systems which retain or enhance the cytotoxic p

285 ate that [S]-PM is a promising targeted drug delivery system, which can be advanced for the treatment

286 ability of a novel nanotechnology-based drug delivery system, which induces recovery of diaphragm fun

287 -sgRNA in vivo has required the use of viral delivery systems, which have limitations for clinical ap

288 examined adult members of a large integrated delivery system who visited an ED for acute heart failur

289 n California, a large integrated health care delivery system, who were hospitalized between 2008 and

290 s, strategies, and approaches by which novel delivery systems will help iterate towards prevention, f

291 with use of MAC in an integrated health care delivery system with a capitated payment model.

292 cell-targeting glucan particle (GP) vaccine delivery system with encapsulated antigen (alpha-synucle

293 For this, it is essential to design a delivery system with the ability to load multiple growth

294 ccharide nanogels are newly explored as oral delivery systems with promising encapsulation potentials

295 o study solid/oil/water (S/O/W) emulsions as delivery systems with retained lactase in milk and contr

296 California (KPNC), an integrated health care delivery system, with health survey and clinical examina

297 rms the high therapeutic efficacy of the new delivery system, with no significant toxicity.

298 The ability to rapidly screen drugs and delivery systems within physiologically relevant environ

299 rapeutic approach with a promising antigenic delivery system without a need for conventional adjuvant

300 ress in vaccine development and immunization delivery systems worldwide, populations in areas of conf