ライフサイエンスコーパス: delta-6-desaturase

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1 tobacco plants expressing the cyanobacterial delta 6-desaturase.

2 and which shares 61% identity with the human Delta-6 desaturase.

3 NA was much lower than that observed for the Delta-6 desaturase.

4 rfectly with the same domains located in the Delta-6 desaturase.

5 racterization, and expression of a mammalian Delta-6 desaturase.

6 e desaturation of 18:2(n-6) and 18:3(n-3) by Delta-6 desaturase.

7 nd nutritional regulation of the Delta-5 and Delta-6 desaturases.

8 omain that is characteristic of nonmammalian Delta-6 desaturases.

9 to 18:2n-6 (P = 9.4 x 10(-7)) as a marker of Delta(6)-desaturase activity significantly predicted the

10 Delta-6 desaturase, also known as fatty acid desaturase-

11 id peptide which is identical in size to the Delta-6 desaturase and which shares 61% identity with th

12 We examined the hypothesis that delta-6 desaturase (D6D), the rate-limiting enzyme in lo

13 The open reading frames for mouse and human Delta-6 desaturase each encode a 444-amino acid peptide,

14 The Delta(6)-desaturase enzyme converts ALA into EPA and DHA

15 prior conclusions regarding the low level of Delta-6 desaturase expression in nonhepatic tissues may

16 Delta(6)-Desaturase (FADS2) is the rate-limiting step in

17 This work identifies Delta-6 desaturase/FADS2 as the major fatty acid desatur

18 Isolation of Delta-6 desaturase/FADS2 cDNA from human skin predicts a

19 ingle locus, together suggestive of a single Delta-6 desaturase/FADS2 gene.

20 nalysis using CHO cells overexpressing human Delta-6 desaturase/FADS2 indicates catalysis of a "polyu

21 Within human skin, Delta-6 desaturase/FADS2 mRNA and protein expression is

22 Similarly, the T. alata delta(6) desaturase favoured T. alata ACP over spinach A

23 seed crops, we have cloned a cyanobacterial delta 6-desaturase gene.

24 to EPA and DHA, and genetic variation in the Delta(6)-desaturase gene (FADS2) may affect this convers

25 e human genome revealed that the Delta-5 and Delta-6 desaturase genes reside in reverse orientation o

26 that could be converted to GLA by the enzyme delta 6-desaturase if it were present.

27 atic activity and mRNA abundance for hepatic Delta-6 desaturase in mice fed corn oil were 70 and 50%

28 vealed that the brain contained an amount of Delta-6 desaturase mRNA that was several times greater t

29 l, the level of hepatic mRNA for Delta-5 and Delta-6 desaturase was only 25% of that found in the liv

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