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1 ase of the number of sulfamoyl groups in the dendrimer.
2 i-PSA antibody and thionine onto AuNPs-PAMAM dendrimer.
3 of the azide groups at the periphery of the dendrimer.
4 dendron, which is equivalent to generation 5 dendrimer.
5 he compactness of the periphery of the G8-OH dendrimer.
6 he hybrid hydrogenated-fluorinated RHF Janus dendrimer.
7 high affinity for DNA possessed by cationic dendrimers.
8 were also coassembled with hybrid RHF Janus dendrimers.
9 ent attachment of Cy5-Trolox conjugates onto dendrimers.
10 of a wide range of novel, dense, and chiral dendrimers.
11 even vary depending on the generation of the dendrimers.
12 nd silver), various other nanomaterials, and dendrimers.
13 nsional order analogous to that of molecular dendrimers.
14 on 4, hydroxyl-functionalized polyamidoamine dendrimers.
15 s into the potential clinical translation of dendrimers.
16 Lewis X antibodies (aSlex)-conjugated PAMAM dendrimers.
17 oated with polypyrrole (PPy) and redox PAMAM dendrimers.
18 jugates with drug moieties buried inside the dendrimers.
19 eased liver and spleen uptake compared to G4 dendrimers.
21 ations and thus successfully converts non-LC dendrimers (1a and 1b) into LC dendrimers (2a and 2b).
28 that loads smaller poly(amidoamine) (PAMAM) dendrimers (~5nm in diameter) into larger poly(ethylene
29 nsor based on polyprrole modified with redox dendrimers, able to detect human cellular prions PrP(C)
30 ybrid NPs encapsulating folate (FA)-targeted dendrimers achieved longer plasma circulation than free
31 bed new types of carriers termed amphiphilic dendrimers (ADs), which are based on polyamidoamine dend
35 yer (LbL) nanofilm of polyamidoamine (PAMAM) dendrimer and carbon nanotubes (CNTs) on capacitive elec
37 chain-branching growth of the assembled DNA dendrimers and an exponential increase in the fluorescen
41 rgent iterative methods for the synthesis of dendrimers and dendrons containing ethylenediamine (EDA)
45 investigate 3rd-6th generation (G3-G6) PAMAM dendrimers and GrO with different levels of oxidation.
47 achieved longer plasma circulation than free dendrimers and higher tumor concentrations than both fre
49 ccessfully combine the in vivo advantages of dendrimers and polymeric NPs, demonstrating their potent
51 nitric oxide (NO)-releasing scaffolds (i.e., dendrimers and silica particles) as anti-periodontopatho
52 ticles (Pd, Pt, Rh) stabilized by G4OH PAMAM dendrimers and supported in SBA-15 (MNPs/SBA-15 with M =
54 liposomes, virosomes, virus-like particles, dendrimers and the like, plus macromolecular drugs, anti
55 t the hybrid NPs circulated longer than free dendrimers and were mostly cleared by macrophages in the
56 itic effect can be observed with any type of dendrimer, and for any type of property, even if it has
57 to the density of functional groups on each dendrimer, and insensitive to factors that promote or in
59 e use of polymeric nanoparticles, liposomes, dendrimers, and inorganic nanoparticles for vaginal drug
63 es, such as polyethylenimine, polyamidoamine dendrimers, and polymyxin B, although they attenuate thr
64 e from commercially available dyes and PAMAM dendrimers, and sensing is based on an indicator displac
67 nylmethane-ethynylene-based shape-persistent dendrimers are a new class of nanoobjects with an intrig
70 erminal functionality, where the majority of dendrimers are directed to the endo-lysosomal compartmen
74 hemically-controlled branched architectures, dendrimers are ideally suited for these initial steps, s
75 chnique was achieved by employing Fe3O4@SiO2-dendrimer as immunosensing platform and PAMAM as the car
77 ymers are a suitable alternative for perfect dendrimers as building blocks for dendritic nanocarrier
78 tention to critically evaluate the status of dendrimers as drug carriers and find answers as to why t
80 4/IL-4Ralpha-targeting peptide with G5 PAMAM dendrimers as the loading surface and can convey therape
82 imine) second (G2) and third (G3) generation dendrimers as well as polyethyleneimine (PEI) were devel
83 ld nanoparticles-incorporated polyamidoamine dendrimer (AuNPs-PAMAM) and multiwalled carbon nanotubes
84 D-aptamer) used as detection probe and PAMAM-Dendrimers/AuNPs was used for covalent attachment of CA1
85 endrimers (PPDs) represent a unique class of dendrimers based on their rigid, shape persistent chemic
86 diagnosis based on the combination of novel dendrimer-based conjugates and a recently developed nano
88 a novel compact nanoplasmonic platform and a dendrimer-based strategy provides a highly sensitive lab
90 have used neutral high-generation phosphorus dendrimers bearing 48 (G3) or 96 (G4) bisphosphonate gro
91 with pyrenyl-functionalized poly(arylester) dendrimers bearing cyanobiphenyl end-groups is reported.
92 ings can potentially alter the perception of dendrimers being limited to carriers to being prodrugs f
94 ee-dimensional crystals of protein cages and dendrimers, by adsorbing proteins to the surface of mate
95 Here we show that the surface-functionalized dendrimers can be sequentially coated with two antibodie
100 terminal exciton delivery efficiency within dendrimers compared with the first linear constructs.
104 nd regulating HT29 cells by the aSlex-coated dendrimer conjugate were analyzed by microscopy and flow
105 f endothelial repair in response to estrogen-dendrimer conjugate, which is a membrane-selective ER li
106 The iterative synthetic protocols used for dendrimer construction were developed based on the desir
108 and substrate encapsulation, an amphiphilic dendrimer containing 27 triethylene glycol termini and 9
109 endrons (RH), while one denoted hybrid Janus dendrimer, contains a combination of chiral-racemic fluo
111 ion (measured by drug CSF/serum level) of G6 dendrimers correlated with the severity of neuroinflamma
112 tra-amniotically administered hydroxyl PAMAM dendrimers could be an effective drug delivery vehicle f
115 g systemic administration of the Cy5-labeled dendrimer (D-Cy5), we demonstrate dendrimer uptake in ce
116 cluding decacyclene- and perylene-containing dendrimer D6, in which two types of polyimide dyes are p
117 Four generations of poly(amidoamine) (PAMAM) dendrimers decorated with benzenesulfonamide moieties we
118 tribution of scFv7F9Cys after conjugation to dendrimers decreased 45 and 1.6-fold respectively, and t
120 w of the most recent synthetic strategies in dendrimer design will be presented for the purpose of co
121 Herein, as a proof-of-concept, a family of dendrimers displaying internally queued disulfide bridge
123 oblems, we herein report molecularly precise dendrimer-drug conjugates with drug moieties buried insi
125 rease with the increased generation of siRNA dendrimers due to a high charge density and structural f
127 , combined with prolonged circulation of the dendrimer, enabled administration of an efficacious dose
128 ent immobilization of polyamidoamine (PAMAM) dendrimer-encapsulated gold nanoparticles (Au-PAMAM) sen
129 For improve the sensitivity, polyamidoamine dendrimer-encapsulated gold nanoparticles (AuNPs-PAMAM)
130 in layer of ALD Al2O3 and an overlayer of Pt dendrimer-encapsulated nanoparticles (DENs) have been in
131 , however, be reactivated by immobilizing Pt dendrimer-encapsulated nanoparticles (DENs), containing
132 iated endocytotic mechanism, irrespective of dendrimer end-terminal functionality, where the majority
133 effects observed with polyphosphorhydrazone dendrimers, even if many examples obtained with other ty
139 disease, the chronic administration of such dendrimers for 5 days led to a much more efficient drop
142 n the injured brain compared to generation 4 dendrimers (G4, 4.3nm), which were undetectable in the
143 ation, hydroxyl-terminated, poly(amidoamine) dendrimers (G6-OH DENs) having diameters of approximatel
145 s of these conjugates were tailorable by the dendrimer generation, surface chemistry, and acidity.
147 al growth (DP=2(n) -1) or double exponential dendrimer growth approaches (DP=22n -1) with significant
148 tive electrophysiology showed that alpha-ImI dendrimers had approximately 100-fold enhanced potency a
149 confirmed that each alpha-ImI moiety in the dendrimers had the same 3D structure as native alpha-ImI
150 ontaining a new, click-synthesized porphyrin dendrimer has been used to map oxygenation across an ex
151 mbly phenomenon of this class of amphiphilic dendrimers has not been molecularly explored using molec
154 numerous examples, two families of inorganic dendrimers have emerged as particularly promising: silic
156 e data suggest that neutral G3-G4 phosphorus dendrimers have strong potential applications in the the
158 e groups are deemed one of the advantages of dendrimers; however, only small amounts of drugs can be
160 d by simple injection of a solution of Janus dendrimer in a water-miscible solvent into water or buff
163 play the main properties of both families of dendrimers in the fields of catalysis, materials and bio
165 -yielding synthesis of a series of polyimide dendrimers, including decacyclene- and perylene-containi
168 tion of transferrin to the polypropylenimine dendrimer increased the DNA uptake by bEnd.3 murine brai
171 f Nanomaterials) to reveal real-time protein-dendrimer interactions using a systems biology approach.
173 y TITAN in a detailed temporal manner during dendrimer internalization, traceable to at least two maj
174 ifurcated, Holliday junction, 8-arm star and dendrimers involving up to five different dyes engaging
175 the stoichiometry of the fluorophore to the dendrimer is 1:1, we were able to directly compare uptak
176 t that transferrin-bearing polypropylenimine dendrimer is a highly promising gene delivery system to
177 errin-bearing generation 3 polypropylenimine dendrimer is therefore a highly promising delivery syste
180 differently when it is alone or linked to a dendrimer; its properties can even vary depending on the
182 d that the conjugation of lactoferrin to the dendrimer led to an enhanced DNA uptake by 2.1-fold in b
184 fect of chemically modified phytoglycogen, a dendrimer-like alpha-d-glucan nanoparticle, on dendritic
185 (6)-10(7) were determined between nanometric dendrimer-like ligands and the rod-shaped micrometric ba
186 ture design tests, including the creation of dendrimer-like structures and scaffolds for small molecu
187 ms, e.g., polymers, nanoparticles, micelles, dendrimers, liposomes, polyplexes, and virus-like-partic
189 ent the proof-of-concept, demonstrating that dendrimer-mediated Akt siRNA delivery, in combination wi
192 rticles, polymer-coated metal nanoparticles, dendrimers, micelles and star polymers to impart nitric
193 40-atom rhodium (Rh) NPs, encapsulated by dendrimer molecules and supported in mesoporous silica,
194 systemic administration of a single dose of dendrimer-N-acetyl cysteine conjugate (D-NAC) at either
197 ultichromophoric probes based on fluorescent dendrimer nanoconjugates (FDNs) was developed for single
198 ts the glyco-conjugate: organic macrocycles, dendrimers, nanomaterials, and polymers are considered.
199 ivered using a targeted, systemic, maternal, dendrimer nanoparticle (DNAC), in a mouse model of intra
200 the presence of pentobarbital increased the dendrimer nanoparticle uptake significantly ( 2-fold bot
201 fully synthetic, single-dose, adjuvant-free dendrimer nanoparticle vaccine platform wherein antigens
203 activate microglia, the increased uptake of dendrimer nanoparticles in their presence can be exploit
205 e by conjugating multiple anti-METH scFvs to dendrimer nanoparticles, extending the scFv half-life fr
207 he mode of uptake, trafficking and safety of dendrimers of different end-terminal functionality (carb
208 ic self-assembly of cationic polyelectrolyte dendrimers of different generations and oppositely charg
209 e polypyrrole film coupled to polyamidoamine dendrimers of fourth generation (PAMAM G4) and ferroceny
210 The MWCNTs-PPy layer was modified with PAMAM dendrimers of fourth generation (PAMAM G4) with covalent
212 present work highlights the robust nature of dendrimer oil dispersion and also illuminates potentiall
213 the immobilization of polyamidoamine (PAMAM) dendrimers on the surface, thus increasing the immobiliz
216 on with a fourth-generation poly(amidoamine) dendrimer (PAMAM(G4)) on gold surface for the immobilisa
218 s particularly promising: silicon-containing dendrimers, particularly carbosilanes, and phosphorus-co
223 y hydrophobic drug molecules anchored on the dendrimer periphery can interact with blood components a
224 ddress this, we used a GnRH peptide-modified dendrimer platform with and without lipidation strategy.
228 been used to discover six amphiphilic Janus dendrimer primary structures, which self-assemble into u
229 rich ssDNA(S1) immobilized on the Fe3O4@SiO2/dendrimers/QDs and AuNPs modified with complementary apt
230 ergy transfer (ECL-RET) approach, Fe3O4@SiO2/dendrimers/QDs exhibited amplified ECL emissions (switch
231 er antigen 125 (CA 125) using polyamidoamine dendrimer-quantum dots (PAMAM-QDs) and PAMAM-sulfanilic
232 zed with either citrate or by low-generation dendrimers rapidly grow during electrocatalytic reductio
236 geting ligand to the surface of pre-existing dendrimers results in poorly-defined compound mixtures t
237 d from a combination of a small RNA with the dendrimer's own negligible toxicity, therefore illuminat
238 njugated to the surface without altering the dendrimer's performance, for example its solubility.
240 ylcholine-detecting nanosensors based on DNA dendrimer scaffolds that incorporate butyrylcholinestera
241 bilization of ferrocene cored polyamidiamine dendrimers second generation (Fc-PAMAM (G2)), after whic
243 bilized redox center (ferrocene) cored PAMAM dendrimers served as a layer for the further binding of
244 n of transverse relaxation times (T2) within dendrimers (shorter values at the core than the peripher
245 sent data indicating that neutral phosphorus dendrimers show impressive antiinflammatory activities b
248 approach also circumvents the nonideality of dendrimers, since the heteroleptic, one-step, spontaneou
251 intended or unanticipated effects of varying dendrimer surface chemistry on their encapsulation or ho
252 perties to polyvalent engagement between the dendrimer surface groups, and a potential "rolling" effe
254 ssed and challenged are the current state of dendrimer synthesis, for example the importance for surf
257 describe the use of a generation 5 l-lysine dendrimer that has been part-modified with a polyoxazoli
258 r SN-38 conjugated to polyoxazoline-modified dendrimer that maximised efficacy and minimised adverse
259 s this issue by reporting modular degradable dendrimers that achieve the required combination of high
261 reak the hydrophobic stereotype, and provide dendrimers that can be synthetically tuned to be used in
264 xylic acid- and pyrrolidone-terminated PAMAM dendrimers through determination of cell membrane integr
266 ols in all living cells, the collapse of the dendrimers to a multitude of smaller thiols was intracel
268 g terminal surface charge on the capacity of dendrimers to disperse model liner, polycyclic aromatic,
269 lation of the dendritic central linker leads dendrimers to possess more isomeric conformations and th
270 s of the utilitarian macromolecules known as dendrimers today, our first examples employed predesigne
272 unctionalized high-molecular weight triazine dendrimers up to generation 9, demonstrating that even v
273 shed by the inhibitory effect of dynasore on dendrimer uptake and changes in temporal profiles of key
274 y5-labeled dendrimer (D-Cy5), we demonstrate dendrimer uptake in cells involved in ischemic injury, a
279 ed 'anionic' (D-COOH) Polyamidoamine (PAMAM) dendrimers were absorbed by fetuses and demonstrated bi-
280 essful, and the resulting carboxy-terminated dendrimers were analyzed by NMR and DOSY experiments.
281 , 809 interacting proteins cross-linked with dendrimers were determined by TITAN in a detailed tempor
283 al poly(amido amine) and poly(propylenimine) dendrimers were substituted with alkyl chains of increas
288 ribe a triethanolamine-core poly(amidoamine) dendrimer which forms stable nanoparticles with the Akt
289 PSA (anti-PSA) was covalently immobilized on dendrimers which were attached onto the modified Au surf
290 on, a dodecaiodo-terminated first generation dendrimer, which was transformed by another Sonogashira
291 owth is now demonstrated as a route to metal dendrimers, which are hierarchically branched nanocrysta
292 ared by derivatizing the amino groups of the dendrimer with 4-carboxy-benzenesulfonamide functionalit
293 nthesis was observed at generation 4 for the dendrimer with an EDA core and at generation 5 for the o
294 into a methoxy-terminated second generation dendrimer with persistent globular shape and well-define
295 is of generation-4 poly-(amidoamine) (PAMAM) dendrimers with a precisely core positioned single sulfo
296 excited-state dynamics in organic conjugated dendrimers with atomistic resolution, a phenomenon expec
298 argeting of intra-amniotically administrated dendrimers with neutral/anionic surface functionality.
299 ion 3-diaminobutyric polypropylenimine (DAB) dendrimer would allow the transport of plasmid DNA to th
300 errin-bearing generation 3-polypropylenimine dendrimer would allow the transport of plasmid DNA to th
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