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1 not disappear when the gut was extrinsically denervated.
2 By 12 h all muscle fibres were denervated.
3 hat 50% of soleus end plates were completely denervated 1-4 weeks post-partial denervation in Hb9(cre
4 adrenalectomized mice were transplanted with denervated adrenal glands to restore physiologic glucoco
5 iaphragmatically vagotomized rats, rats with denervated adrenal medullae and rats with acutely transe
8 (Id2) and c-Myc protein contents between the denervated and control muscles, the protein content of t
11 growth factor-1 was expressed vigorously by denervated and reinnervated cutaneous nerve but minimall
12 imaging can be used to differentiate between denervated and reinnervated muscles for at least 12 mont
13 fter nerve repair, and signal intensities of denervated and reinnervated muscles were measured semiqu
14 n either renal function or structure between denervated and sham-operated animals treated with cyclos
17 jected into the liver of parasympathetically denervated animals and orexin fibres were found adjacent
23 erative axonal sprouts grew into the central denervated area in a stereotypic pattern with collateral
26 SS shortened ARI in 30% of electrodes in the denervated area, with increased shortening and dispersio
27 SS prolonged ARI in 70% of electrodes in the denervated area, with no correlation with severity of de
31 ojections from the undamaged hemisphere into denervated areas of the spinal cord and improves skilled
34 s that induce retinal axons to innervate the denervated auditory thalamus may compete with barriers,
36 er electroporation is sufficient to rescue a denervated blastema and regenerate the distal structures
37 in-2, which we then engrafted into partially denervated branches of the sciatic nerve of adult mice.
41 adult brain to form new connections in areas denervated by a lesion (axonal sprouting) is more widesp
44 lamic and thalamocortical axons and are thus denervated by such injuries, yet nRT cells generally sur
46 t cardiac vagal branches but sympathetically denervated by thoracic spinal pithing, cardiac chronotro
48 significant manner; 2) the fine structure of denervated cells is altered; 3) cell phenotypes are diff
53 ally invasive therapeutic avenue to exercise denervated circuitry and/or restore motor function after
55 while infarcts in ptprs+/- littermates were denervated, confirming that CSPGs prevent sympathetic re
56 otransporter was elevated in interneurons of denervated cortex, and KCC2 deletion restored normal int
58 protein were significantly more abundant in denervated cutaneous nerve than in denervated ventral ro
59 ixed tissues, by using time-lapse imaging of denervated dentate granule cells in organotypic entorhin
61 this process and can rescue regeneration in denervated digit tips through secretion of pro-regenerat
63 hin (PTN) was highly up-regulated in acutely denervated distal sciatic nerves, but high levels of PTN
68 spared fibers in the ventral striatum to the denervated dorsal striatum at 7 weeks post-lesion, but t
69 When segmental data were further analyzed in denervated (DZ), transition (TZ), and normal (NZ) zones,
72 incision model, the earliest reinervation of denervated epidermis occurred by collateral sprouting fr
73 d there were no differences in heart rate in denervated ex vivo hearts, implicating parasympathetic h
74 mbs walked freely, the experimental limb was denervated except for the nerves to MG and TA and secure
78 gate the role of muscle impulse activity, we denervated fast extensor digitorum longus (EDL) and slow
79 to what extent, if any, muscle fascicles of denervated feline soleus (SO) change length during stanc
83 itability in SD fibres since many normal and denervated fibres retain normal excitability when depola
84 increased the action potential threshold in denervated fibres to that measured in innervated fibres,
87 were analyzed for the subset (n=27) who were denervated for an underlying diagnosis other than autoso
88 tions severed S-cell axons did not reach the denervated ganglion but grew close to it, independent of
89 sected mouse tibial nerve projected axons to denervated gastrocnemius muscle fibers, where they forme
90 contralateral CST axon sprouting toward the denervated gray matter of the cervical and lumbar spinal
93 evealed two populations of NMJs in partially denervated Hb9(cre)NCAM(flx) soleus muscles, one with hi
95 frequently in heart transplant patients with denervated hearts and coronary allograft vasculopathy, a
96 Transcriptional analysis of mechanically denervated hearts revealed a blunted inflammatory and im
101 hetic ingrowth occurs in the cholinergically denervated hippocampus at 4, 8 and 12 weeks post Saporin
105 ed in enteric neurons from nondenervated and denervated ileal segments of guinea pig after abdominal
106 DA-receptor antagonists in nondenervated and denervated ileal segments, but not by the AMPA-receptor
107 In the animal model, skeletal muscle is denervated in rats treated with high-dose corticosteroid
109 Restoration of substance P (SP) signaling in denervated KC-Tie2 skin prevented decreases in CD11c(+)
110 d pressure, only reduced inflammation in the denervated kidney, suggesting that this effect is pressu
111 nd calcitonin gene-related peptide (CGRP) in denervated kidneys mimicked the fibrotic response observ
112 ge infiltration/inflammation was enhanced in denervated kidneys, not explained by angiotensin II leve
114 lastema, capable of rescuing regeneration in denervated limbs, and its inhibition must prevent regene
115 aked beads rescued regeneration to digits in denervated limbs, and pharmacological inhibition of NRG1
118 muscles were initially innervated, but later denervated, loss of innervation in SMA may be attributed
120 stem/progenitor cell markers and assessed in denervated mice versus controls by immunofluorescent mic
125 nd clusterin (CLU) which were upregulated in denervated motor and sensory pathways, respectively.
129 borative fashion to inhibit reinnervation of denervated mouse skeletal muscle and appear to act, at l
131 er one similar to fibres from experimentally denervated muscle (TTX resistant), and a third group int
132 inishes expression of MuRF1 and atrogin-1 in denervated muscle and confers resistance to atrophy.
133 elaxation time and gadolinium enhancement of denervated muscle develop in parallel to the development
134 usly, we demonstrated that mitochondria from denervated muscle exhibited dramatically higher Amplex R
135 Mass spectrometry of the bound proteins in denervated muscle identified many myofibrillar component
136 f the Amplex Red signal in mitochondria from denervated muscle is not derived from hydrogen peroxide.
138 he release of fatty acid hydroperoxides from denervated muscle mitochondria may be an important deter
143 alpha7* nAChRs are significantly present on denervated muscle, and that these receptors display unus
154 olemma of freshly isolated WT myofibers from denervated muscles also showed high hemichannel-mediated
157 Administration of rAAV:Fst to innervated or denervated muscles increased protein synthesis, but mark
158 t of the depolarization was never present in denervated muscles obtained from mutant mice lacking the
160 gastrocnemius muscles, but only unloaded and denervated muscles showed a marked increase in Nedd4 pro
163 regulatory sequences by directly stimulating denervated muscles with pattern that mimic fast and slow
168 rest was correlated with a greater volume of denervated myocardium (defect of the positron emission t
170 is required to sustain muscle by preventing denervated myofibers from undergoing myofibrillar disorg
172 tes a degenerative process that converts the denervated nerve from a suppressive environment to one t
176 sprout collaterals to reinnervate previously denervated neuromuscular junctions concurrently with exp
177 e as they regenerate and ultimately reoccupy denervated neuromuscular synaptic sites to learn what ch
178 uronal loss by providing extra excitation of denervated neurons, is the most relevant form of adaptiv
179 Collectively, these findings indicate that denervated neurotrophic ulcers are associated with poor
180 ia is significantly impaired, with increased denervated NMJs and fragmentation of acetylcholine recep
184 ) into the cuneate nucleus of rats partially denervated of forepaw dorsal column axons was examined.
185 ecially dense LC innervation, is selectively denervated of LC input or is ablated by the cell-specifi
188 d the structure of the cells that form them, denervated or repair Schwann cells, remains obscure.
192 receptor density, and endplate morphology in denervated plantaris muscles in wild-type and MMP3 null
193 atients, with unpleasant sensory symptoms in denervated posterior cervical segments occurring in 14.
194 synaptic transmission in the normal and the denervated PrV of neonatal rats in an in vitro brainstem
195 model of critical illness myopathy in which denervated rat skeletal muscle is treated with corticost
196 model of critical illness myopathy in which denervated rat skeletal muscle is treated with corticost
197 sion of the mGluR5 antagonist MTEP in the DA-denervated rat striatum attenuated the activation of ERK
198 ion were induced in the striatum of dopamine-denervated rats naive of chronic drug administration.
203 dual restoration of synaptic function in the denervated region, as revealed by extracellular microele
204 ded axon and Schwann cell migration into the denervated region, perhaps acting as scaffolding for axo
207 the bulb, 2) the fine structure of cells in denervated regions is disrupted, and 3) cellular phenoty
210 afts of cutaneous nerve or ventral root were denervated, reinnervated with cutaneous axons, or reinne
212 hed in chronically decentralized SCG but not denervated SCG, suggesting the preganglionic origin.
215 nal path, providing compelling evidence that denervated Schwann cells actively direct regenerating ax
216 eneration and atrophic changes that occur in denervated Schwann cells and target muscle with proximal
217 nteraction in the Remak bundles of partially denervated Schwann cells and unmyelinated axons, or the
219 rst 50 days following nerve transection, the denervated Schwann cells in the dermis were easily ident
220 show here that medium conditioned by primary denervated Schwann cells or the Schwannoma cell line RN2
221 first demonstration that repair capacity of denervated SCs can be efficaciously enhanced without alt
222 n SCs but not impede transdifferentiation of denervated SCs to regeneration-promoting repair SCs.
223 ated with high-dose corticosteroids (steroid-denervated; SD), and muscle fibers become inexcitable de
226 hat were significantly upregulated in either denervated sensory or motor pathways were identified and
227 s and upregulation of receptors on partially denervated serotonergic targets in the spinal cord.
228 d that corticospinal fibers sprouting to the denervated side of the cord following pyramidotomy conta
229 ed substantial axon outgrowth to the largely denervated side of the spinal cord and restored normal m
230 om neurons in the intact hemisphere into the denervated side of the spinal cord compared with either
231 of these neurons to form connections on the denervated side of the spinal cord, and improves perform
234 hich SK channel activity in the T-tubules of denervated skeletal muscle causes a local increase in K+
239 , regenerating and uninjured axons grew into denervated skin and competed with one another for territ
240 models can be used to study reinnervation of denervated skin in man in different injury models and ha
241 at sound sensory function is provided to the denervated skin of the residual limb when connected to a
242 ons to sprout collateral axons into adjacent denervated skin, indicating a critical role for intact I
245 ngs suggest that myofascial linkages between denervated SO and its active synergists might affect its
246 ked reduction in midorbital cross section in denervated SO muscles, with anterior shift of SO mass pr
248 tory reinnervation was explored by partially denervating soleus muscles in mice lacking presynaptic N
249 hemisphere are capable of sprouting into the denervated spinal cord after TBI and EPO treatment, whic
250 ances axonal sprouting and rewiring into the denervated spinal cord which may facilitate functional r
251 extensive sprouting of their axons into the denervated spinal cord white matter and adjacent neuropi
255 relays to restore supraspinal regulation of denervated SPNs, thereby contributing to cardiovascular
258 ntralateral corticostriatal neurons into the denervated striatum after ischemic cortical lesions.
260 hat D1-dependent ERK1/2 activation in the DA-denervated striatum depends on a complex interaction bet
261 at the ERK signaling pathway is activated in denervated striatum in response to stimulation of D(2) d
263 mbryonic day 14 (E14) and implanted into the denervated striatum of rats with unilateral 6-hydroxydop
264 hese dopamine receptor genes in the dopamine-denervated striatum of rodents to reveal whether their o
265 fter stereotactic delivery into the dopamine-denervated striatum of the 6-OHDA-lesioned rat, sustaine
266 higher trkB mRNA probe hybridization in the denervated striatum than in the intact striatum at the s
267 signature induced by L-DOPA in the dopamine-denervated striatum that is dependent on ERK and associa
268 terestingly, in old rats BDNF protein in the denervated striatum was significantly lower than that me
269 n levels of BDNF and GDNF were higher in the denervated striatum when compared to the intact striatum
270 nsatory increase of these two factors in the denervated striatum while no compensatory increase is ob
275 the eye, where, sporadically, patients with denervated sympathetic fibers develop chronic inflammati
276 nternalized nAChRs into fully functional and denervated synapses was promoted by both direct muscle s
277 hat axons restore synaptic connectivity with denervated targets several centimeters from the site of
279 CNS, axons must be stimulated to extend into denervated territory and, critically, must form function
280 hat treatment with the AI 4-OH-A essentially denervates the zebrafish trunk skeletal muscles, most li
281 ious work introduced a technique for focally denervating the olfactory bulb soon after birth and desc
284 3rd and 4th week, probe hybridization in the denervated/transplanted and intact striatum were the sam
285 The carotid sinus nerves were surgically denervated under general anaesthesia in 4- and 12-week-o
287 undant in denervated cutaneous nerve than in denervated ventral root, but that PTN protein was more a
291 kin 4; and fewer myofibroblast infiltration (denervated vs intact: 1.2 +/- 0.2 vs 3.2 +/- 0.6 cells/v
292 e infiltration of macrophages was increased (denervated vs intact: 112 +/- 8 vs 76 +/- 9 cells/visual
293 percentage of M2 macrophages was decreased (denervated vs intact: 31 +/- 4 vs 57 +/- 9%; p < 0.05, n
294 architecture; decreased collagen deposition (denervated vs intact: COL1alpha1, 19.1 +/- 2.2 vs 22.0 +
296 sity in rat hearts that have been chemically denervated with 6-OHDA, suggesting that HED retention is
297 morphologies on post-synaptic spines in the denervated Wld(S) striatum indicating an enhanced plasti
299 presence of de novo dendritic spines in the denervated zone suggests that the postlesion environment
300 neurons showed reduced complexity within the denervated zone, but dendritic spines still formed in th
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