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2 compared with a single environment, promoted dentate activation and enhanced the addition of new hipp
4 riodontal conditions were assessed for 1,911 dentate adults with a full-mouth periodontal examination
5 tolerated and was associated with a reduced dentate and caudate nucleus iron content compared to pla
6 were assessed in the substantia nigra (SNc), dentate and caudate nucleus, red nucleus, putamen and gl
7 hite adult individuals, dentate or partially dentate and seeking dental therapy at a university clini
10 ks to assess experience-dependent changes in dentate field potentials in the presence and absence of
14 tand how monosynaptic inputs onto adult-born dentate granule cells (DGCs) are altered in experimental
15 h CA3 interneurons peak when adult-generated dentate granule cells (DGCs) are approximately 4 weeks o
18 the developing dendrites of adult-born mouse dentate granule cells (DGCs) in vivo and found that they
19 systems-based mechanisms by which adult-born dentate granule cells (DGCs) modulate pattern separation
20 Local application of FGF22 on the axons of dentate granule cells (DGCs), which are presynaptic to C
22 Cs) in the dentate gyrus receive inputs from dentate granule cells (GCs) and project back to GCs loca
23 for a novel, highly detailed active model of dentate granule cells (GCs) replicating a wide palette o
24 ect link between the primary cilia of mature dentate granule cells and behavior will require further
25 ins IFT20 and Kif3A (respectively) in mature dentate granule cells and investigated hippocampus-depen
26 an electrophysiology-based classification of dentate granule cells and mossy cells in mice that we va
27 ong-standing hypothesis that newly generated dentate granule cells are pro-epileptogenic and contribu
28 ppocampal adult neurogenesis, and adult-born dentate granule cells contribute to the pathologic retro
31 port chain of mitochondria, from hippocampal dentate granule cells in mice does not affect low-freque
32 primary cultures of rat hippocampal neurons, dentate granule cells in mouse organotypic slices, and l
33 res of rat hippocampal and cortical neurons, dentate granule cells in mouse organotypic slices, and l
37 ssy cells are significantly more active than dentate granule cells in vivo, exhibit spatial tuning du
38 mpal neurons in vitro and in vivo Adult-born dentate granule cells lacking Trim9 similarly exhibited
39 required for structural synapse formation in dentate granule cells or for Shh-dependent neuronal prec
41 Genetic ablation of AKAP7 specifically from dentate granule cells results in disruption of MF-CA3 LT
43 e glutamatergic cell types, including mature dentate granule cells, area CA1-3 pyramidal cells and mo
44 imary cilia in the memory function of mature dentate granule cells, which may result from abnormal mo
53 atin accessibility landscapes of adult mouse dentate granule neurons in vivo before and after synchro
54 in vivo Embryonic hippocampal and adult-born dentate granule neurons lacking Trim9 exhibit several mo
57 s selectively increased in CA1 pyramidal and dentate granule neurons, as well as in microglia in mice
58 ogical approaches that Oxtrs in the anterior dentate gyrus (aDG) and anterior CA2/CA3 (aCA2/CA3) of m
59 ies have provided indirect evidence that the dentate gyrus (DG) and CA3 hippocampal subregions suppor
60 at mossy fiber (mf) connections between the dentate gyrus (DG) and CA3 neurons in vivo are still elu
61 tatin-expressing-interneurons (SOMIs) in the dentate gyrus (DG) control formation of granule cell (GC
63 rly gene (IEG) induction in stress-activated dentate gyrus (DG) granule neurons play a crucial role i
64 the cornu ammonis (CA) subfields CA1-4, the dentate gyrus (DG) including a granule cell layer (GCL)
65 CK) inhibitory interneurons of the mammalian dentate gyrus (DG) initiate the therapeutic response to
71 nd DISC1 influence adult neurogenesis in the dentate gyrus (DG) of the hippocampus, we hypothesized t
72 Cs resulted in fewer adult-born cells in the dentate gyrus (DG) overall, reducing populations across
73 spite abundant evidence that the hippocampal dentate gyrus (DG) plays a critical role in memory, it r
74 brain varied between 6.6 +/- 0.7 muM in the dentate gyrus (DG) region of the hippocampus and 22.1 +/
75 d S1 cortex, decreased NLGN2 mRNA in CA1 and dentate gyrus (DG) regions of the hippocampus, and incre
76 re indicative of a disrupted function of the dentate gyrus (DG) subregion of the brain, and they impr
80 subfields cornu ammonis 2/3 (CA2/3) and CA4/dentate gyrus (DG), as well as impaired hippocampal micr
81 of neural stem cells (NSCs) in the postnatal dentate gyrus (DG), drastically increased perinatal apop
82 or, olfaction, and adult neurogenesis in the dentate gyrus (DG), olfactory bulb (OB), and the olfacto
83 neural progenitors in the adult hippocampal dentate gyrus (DG), one of the select regions of the mat
84 dult brain, like the subgranular zone of the dentate gyrus (DG), there is continuous production of ne
85 coding mechanism, pattern separation, in the dentate gyrus (DG)-CA3 circuit in resolving interference
92 with decreased mean diffusivity of the left dentate gyrus (p = 0.002; false discovery rate corrected
93 es 11 to 18 years forecasted diminished left dentate gyrus (simple slope, -14.20; standard error, 5.2
94 in hippocampal staining: CB(+) decreased in dentate gyrus (TBI = 2 +/- 0.382, Sham = 4 +/- 0.383, P
95 ify a role for the astroglial xCT in ventral dentate gyrus (vDG) in stress and antidepressant respons
97 d THY-Tau22 mice developed an atrophy of the dentate gyrus and a tau pathology characterized by Gally
98 ongly decreased stimulation-induced EPSPs in dentate gyrus and CA1 (up to 30 and 55%, respectively) v
101 ociation of years lived in poverty with left dentate gyrus and CA3 hippocampal subfields and left amy
103 We performed RNA sequencing analyses of the dentate gyrus and entorhinal cortex from each line and f
105 ChAT-ir fibers were seen throughout the dentate gyrus and hippocampus, in the mediodorsal, later
106 Adult neurogenesis persists in the rodent dentate gyrus and is stimulated by chronic treatment wit
107 AMPAR-mediated synaptic transmission in the dentate gyrus and long-term potentiation in the CA1 regi
109 a thus support a sparse coding scheme in the dentate gyrus and provide a possible link between struct
110 eurogenesis in the granule cell layer of the dentate gyrus and rescues hippocampal memory defects in
111 gions of the vertebrate brain, including the dentate gyrus and rostral migratory stream in mammals, a
114 d incorporation of adult-born neurons in the dentate gyrus are critical for spatial learning and memo
116 RK2 alone does not impair development of the dentate gyrus as animals expressing only ERK1 developed
117 ions in local inhibitory function within the dentate gyrus at time points where sparse activation was
118 born neurons are continually produced in the dentate gyrus but it is unclear whether synaptic integra
119 ride regulation was sufficient to elicit the dentate gyrus circuit collapse evident during epilepsy d
120 thin the local circuit generates the massive dentate gyrus circuit hyperactivation evident in animals
122 sy to test which pathological changes in the dentate gyrus correlate with seizure frequency and help
124 nhibition of adult neurogenesis in the mouse dentate gyrus decreases hippocampal network activation a
125 We also demonstrate that an ablation of dentate gyrus engram cells containing restored spine den
126 m potentiation at perforant path synapses of dentate gyrus engram cells restores both spine density a
128 allowed targeted fatty acid analysis of the dentate gyrus granule cell layer and the CA1 pyramidal l
129 bors and dendritic spines in newly generated dentate gyrus granule cell neurons of the hippocampus af
130 aGABAA receptor-mediated tonic inhibition in dentate gyrus granule cells (DGGCs), thereby contributin
131 e identified more than 40 lipid species from dentate gyrus granule cells and CA1 pyramidal neurons of
132 at allows for chronic, functional imaging of dentate gyrus granule cells in awake, behaving mice in a
133 ional' nature implies that burst activity in dentate gyrus granule cells is required for detonation.
135 citability by modulating tonic inhibition in dentate gyrus granule cells, in a process involving cros
139 all subfields, whereas TLE-G presented with dentate gyrus hypertrophy, focal increases in T2 intensi
140 evidence of disrupted microstructure of the dentate gyrus in children with OSAS that may help explai
141 We demonstrate lower mean diffusivity of the dentate gyrus in children with OSAS, which correlates wi
142 s, we demonstrate distinct roles for CA3 and dentate gyrus in human memory and uncover the variegated
143 ced aberrant neurogenesis in the hippocampal dentate gyrus in the context of the blood-brain barrier
144 rphosphorylation of tau was increased in the dentate gyrus in THY-Tau22 mice, the development of neur
149 attenuated BDNF release and signaling in the dentate gyrus may account for cognitive and mental defic
150 verbal learning score correlated with lower dentate gyrus mean diffusivity (r = 0.54, p = 0.004).
151 hildren, as well as potential utility of the dentate gyrus mean diffusivity as an early marker of bra
154 stic accuracy of a regression model based on dentate gyrus mean diffusivity reached 85.8% (cross vali
155 , we report that deletion of Drosha in adult dentate gyrus NSCs activates oligodendrogenesis and redu
157 rneuron-selective calretinin-ir cells in the dentate gyrus of hippocampal-kindled rats, which suggest
158 newly-incorporated DNA were observed in the dentate gyrus of hippocampus at the single cell level.
160 progenitor cells isolated directly from the dentate gyrus of MBD1 mutant (KO) and WT mice showed tha
161 e of a dramatic shift in excitability in the dentate gyrus of Pafah1b1(+/-) mice that may contribute
162 on of Ephexin5 expression using shRNA in the dentate gyrus of presymptomatic adolescent hAPP mice was
164 pressed in neural stem cells residing in the dentate gyrus of the adult hippocampus (aNSCs) and MBD1
165 evelopmental stages are recapitulated in the dentate gyrus of the adult hippocampus, where neurons ar
166 ly, physical EE promoted neurogenesis in the dentate gyrus of the hippocampal formation, but not in t
168 lished that new neurons are generated in the dentate gyrus of the hippocampus of almost all adult mam
169 ure neurons, and fewer mature neurons in the dentate gyrus of the hippocampus of the mouse brain.
172 eight paired helical filaments (PHFs) in the dentate gyrus of wild-type and mutant tau THY-Tau22 mice
173 t inhibitory synapses in hippocampus CA1 and dentate gyrus of young presymptomatic APPPS1 mice (1 to
174 t inhibition of the principal neurons of the dentate gyrus or CA3 via alpha2-containing GABAA recepto
175 infusion did not affect spine density in the dentate gyrus or ventromedial hypothalamus, suggesting s
177 Excitatory hilar mossy cells (MCs) in the dentate gyrus receive inputs from dentate granule cells
178 al VitB12, mainly in the cornu ammonis 4 and dentate gyrus region (P= 0.029), which partially mediate
180 udy we investigate the relationships between dentate gyrus structure, hippocampus-dependent cognition
181 ynapses were frequently found in the CA3 and dentate gyrus sub-regions, corresponding to large thorny
183 d progressive microstructural changes in the dentate gyrus translate to the severity of hippocampal s
185 hods to show that EE alters microglia in the dentate gyrus under physiological conditions and robustl
187 pattern separation task, we demonstrate that dentate gyrus volume predicts accuracy and response time
190 of juxtacellularly recorded cells in CA1 and dentate gyrus were modulated by HRR and theta oscillatio
191 subfield (subiculum, cornu ammonis 1-3, and dentate gyrus) targets of immunomodulation-treated LGI1
192 We hypothesized that OSAS would affect the dentate gyrus, a hippocampal subdivision essential to ne
193 tic GABAA receptors in the mouse hippocampus dentate gyrus, a key region associated with epilepsy and
196 f inhibitory interneurons in the hippocampal dentate gyrus, an important area for seizure propagation
198 namely, granule cells and mossy cells of the dentate gyrus, and pyramidal cells of areas CA3, CA2, an
199 a critical role of the Ptchd1 protein in the dentate gyrus, but indicate that it is not required for
200 n- and somatostatin-positive interneurons in dentate gyrus, but no change in density of calretinin in
201 clude the basolateral amygdaloid nucleus and dentate gyrus, but the septohippocampal nucleus, lateral
202 s, alpha1 and alpha3 were accentuated in the dentate gyrus, CA1 region, and subiculum, whereas alpha5
204 ot suppress ECS-induced proliferation in the dentate gyrus, it blocks dendritic outgrowth of immature
205 e synapse remodeling and neurogenesis in the dentate gyrus, mechanistic studies have revealed both ge
207 ain injury can integrate abnormally into the dentate gyrus, potentially mediating temporal lobe epile
208 us.SIGNIFICANCE STATEMENT In the hippocampal dentate gyrus, seizures drive retrograde sprouting of gr
211 n the activation of neural stem cells in the dentate gyrus, their division, and differentiation of th
212 vious observations in the monkey hippocampal dentate gyrus, where MSBs comprised approximately 40% of
213 equency rhythm with largest amplitude in the dentate gyrus, which coupled to respiration-entrained os
214 s of neural stem cell differentiation in the dentate gyrus, with higher expression intensity in neuro
215 s fibres in the medial entorhinal cortex and dentate gyrus, with no frank noradrenergic cell body los
242 agation pathway of ictal discharges from the dentate gyrus/hilus (DGH) to the medial entorhinal corte
247 ntial role of both cholinergic sprouting and dentate hyperactivity in AD symptomatogenesis should be
250 ing a terpyridine (tpy)-based, flexible tris-dentate ligand and characterized by single crystal X-ray
251 e rigidity, one of the tpy units of the tris-dentate ligand was preblocked by stable <tpy-Ru(2+)-tpy>
252 ation-inhibition coupled neural synchrony in dentate local field potentials was reduced in X-irradiat
253 epilepsy, involving fiber sprouting into the dentate molecular layer and a parallel fiber retraction
255 itory synapses in the inner one-third of the dentate molecular layer was Glu-CB1 -RS, 53.19% (glutama
256 rol rats in the inner and outer zones of the dentate molecular layer, but it was reduced in the denta
257 17) distinguish in vivo firing properties of dentate mossy cells from granule cells during behavior.
260 d that Bax deletion in developing and mature dentate neurons increased EPSCs and prevented neurogenes
262 nmt3a, is critical for the responsiveness of dentate neurons to environmental stimuli in terms of gen
265 magnetic resonance (MR) imaging, cerebellar dentate nuclei (DNs) functional connectivity abnormaliti
269 images relative to reference tissues in the dentate nucleus (0.53% signal intensity increase per inj
270 ighted signal intensity (SI) increase in the dentate nucleus (DN) and globus pallidus (GP) in relatio
271 eglumine on the signal intensity (SI) of the dentate nucleus (DN) of the pediatric brain on nonenhanc
272 (GBCAs) on the signal intensity (SI) of the dentate nucleus (DN) on unenhanced T1-weighted magnetic
273 est for measurable visual enhancement of the dentate nucleus (DN) on unenhanced T1-weighted magnetic
274 ) in the globus pallidus (GP), thalamus (T), dentate nucleus (DN), and pons (P) were measured on unen
275 llowing five regions of interest (ROIs): the dentate nucleus (DN), pons, substantia nigra (SN), pulvi
276 minations had increased SI ratios within the dentate nucleus (mean SI ratio +/- standard error of the
277 wed visually detectable T1 shortening in the dentate nucleus (n = 13), globus pallidus (n = 13), subs
278 .026) and T2 of the whole brain (P = .004), dentate nucleus (P = .023), and thalamus (P = .002) show
279 rain (P < .001), globus pallidus (P = .002), dentate nucleus (P = .046), and thalamus (P = .026) and
280 en, pallidum, thalamus, midbrain, and in the dentate nucleus of the cerebellum (t's > 2.7, P's < 0.02
281 putamen, subthalamic nucleus, midbrain, and dentate nucleus relative to controls and PD patients (vo
282 [CI]: 0.03, 0.67; P = .03), but not between dentate nucleus SI and patient age (r = 0.23; 95% CI: -0
283 There was a significant correlation between dentate nucleus SI and total cumulative gadolinium dose
284 Unenhanced T1 signal intensities of the dentate nucleus were measured from magnetic resonance (M
286 The SI in the globus pallidus, thalamus, dentate nucleus, and pons was measured at unenhanced T1-
287 ior cingulate, inferior temporal lobule, the dentate nucleus, and the cerebellar lobules IV/V, VI, an
288 ls in the basal ganglia, midbrain, thalamus, dentate nucleus, cerebellar peduncles, cerebellar vermis
289 levated free-water in all regions except the dentate nucleus, subthalamic nucleus, and corpus callosu
297 We evaluated these alternatives by using dentate-sensitive active place avoidance tasks to assess
298 disorders, interaction between human CA3 and dentate subfields is difficult to investigate due to sma
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