ライフサイエンスコーパス: dentine

1 terior group) for 2 tissue types (enamel and dentine).

2 secrete new "tertiary" dentine (reactionary dentine).

3 rface of existing dentine and rethickens the dentine.

4 cipal skeletal tissue of dermal denticles is dentine.

5 tive dentine formation to completely restore dentine.

6 in more disorganized, nontubular reactionary dentine.

7 ontoblast-like cells that secrete reparative dentine.

8 nd alkaline phosphatase in DPSCs cultured on dentine.

9 the durability of adhesive bonds created in dentine.

10 osphoric acid, and citric acid from powdered dentine.

11 ulation of exposed dentine and to drying the dentine.

12 n mechanism that involves fluid flow through dentine.

13 rentiation and reduced resorption of pits in dentine (3 to 100 microM; P<0.001).

14 Dentine also exhibited microwear characteristics that we

15 A set of genes for dentine and bone extracellular matrix proteins constitut

16 The teeth are composed of dentine and bone, and show a distinct pulp cavity that i

17 New teeth are composed of gnathostome-type dentine and develop at specific locations.

18 nding not only of biominerals (such as bone, dentine and enamel), but also of synthetic organic-inorg

19 is formed on the pulpal surface of existing dentine and rethickens the dentine.

20 i in teeth.In 11 animals, fluid flow through dentine and single- and multi-unit activity in intradent

21 ssure, and mechanical stimulation of exposed dentine and to drying the dentine.

22 d, and citric acid exposed growth factors on dentine and triggered an upregulation in genes associate

23 failed to solubilize proteins from powdered dentine and was therefore considered ineffective in trig

24 ites) associated with a pigmentation line in dentine and with a distinct neonatal line in enamel.

25 However, phosphoric acid-treated dentine appeared strikingly less populated with cells, s

26 Our results support that Mn levels in mantle dentine are useful in discerning perinatal Mn exposure,

27 ooth pulp, maintenance of as much unaffected dentine as possible is a major goal during the physical

28 noted in dentine erosion for complexity and dentine attrition for anisotropy.

29 ially stacked, multigenerational, jaw-length dentine bands, before development of the functional beak

30 Although adhesive restorations and dentine-bonding procedures are routinely practiced, clin

31 forecasting the decline in strength of resin-dentine bonds created in vivo.

32 he deposition of mineral to form reactionary dentine but does play a role in its organization.

33 o major role in the formation of reactionary dentine, but in common with reparative dentine formation

34 of the sequestrated bioactive molecules from dentine by the action of applied dental materials has be

35 of the ability of the adhesives to stick to dentine, clinical studies show that these fillings are r

36 eases in heat shock protein-70 expression in dentine coincided with elemental signatures, confirming

37 cial steps in informing clinical practice on dentine-conditioning protocols as far as treatment of op

38 roportion of children developing caries into dentine (D4-6MFT) on any 1 of up to 4 treated FPMs after

39 e into odontoblast-like cells in response to dentine damage.

40 hile other bone tissues, such as human tooth dentine, develop slowly and maintain constant compositio

41 Dentine dysplasia type II is an autosomal dominant disor

42 equencing DSPP in a family with a history of dentine dysplasia type II.

43 -existing enamel matrix glycoproteins at the dentine-enamel junction.

44 Amelogenins bind to GlcNAc of the dentine-enamel matrix proteins.

45 The greatest geometric means were noted in dentine erosion for complexity and dentine attrition for

46 Dinosaur dentine exhibits growth lines that are tens of micromete

47 rosaurs and ceratopsians can be explained by dentine formation constraints and rapid tooth wear.

48 to investigate the mechanisms of reactionary dentine formation in vivo, using small molecules to modu

49 th size, which was due to limitations in the dentine formation rates of their odontoblasts.

50 promote the natural processes of reparative dentine formation to completely restore dentine.

51 or Wnt pathways does not impede reactionary dentine formation, although inhibition of TGF-beta and/o

52 The lines likely reflect daily dentine formation, and they were used to infer tooth dev

53 onary dentine, but in common with reparative dentine formation, exogenous elevation of Wnt/beta-caten

54 ntagonists, resulting in enhanced reparative dentine formation.

55 /beta-catenin signaling can enhance tertiary dentine formation.

56 ciduous teeth, to identify regions of mantle dentine formed at different prenatal periods.

57 Mn levels in mantle dentine formed during the second trimester (as (55)Mn:(4

58 urrounding hollow tracts that exist in human dentine forming dentinal tubules.

59 f mechanism-based therapeutic approaches for dentine hypersensitivity and inflammatory tooth pain.

60 The mechanism of pain in dentine hypersensitivity is poorly understood but propos

61 its rabbit osteoclast-mediated resorption of dentine in a cellular assay, exhibits bone-targeting pro

62 s as far as treatment of operatively exposed dentine in teeth with vital pulps is concerned.

63 Release of latent TGF-beta or BMPs from dentine is not required for the deposition of mineral to

64 s the greatest functional role at the enamel-dentine junction (EDJ), as it was the region that exhibi

65 Using enamel-dentine junction morphology, enamel thickness and compar

66 Damage to dentine leads to release of fossilized factors (transfor

67 The restoration of dentine lost in deep caries lesions in teeth is a routin

68 Growth factors were detected in dentine matrix extracts drawn by EDTA, phosphoric acid,

69 The dentine matrix extracts were shown to be bioactive, capa

70 al mesenchyme, dental papilla, odontoblasts, dentine matrix, pulp, cementum, periodontal ligaments, c

71 rosensory system, and the archival nature of dentine microstructure, allows the development of 'biolo

72 sis imperfecta type II, a second disorder of dentine mineralization, it has been proposed that the tw

73 nant disorder in which mineralization of the dentine of the primary teeth is abnormal.

74 us FS ( n = 82, 19.6%) developed caries into dentine on at least 1 FPM (odds ratio [OR] = 0.84; 95% C

75 at and rabbit mature osteoclasts cultured on dentine or explants of mouse calvariae prelabeled with (

76 of function of both dentine sialoprotein and dentine phosphoprotein.

77 This study investigated the effect of dentine (powder and slice) conditioning by etchants/cond

78 cranial neural crest cells give rise to the dentine-producing cells (odontoblasts) of teeth.

79 ulate odontoblasts to secrete new "tertiary" dentine (reactionary dentine).

80 cal protocols to improve pulp protection and dentine regeneration are not currently driven by biologi

81 ce the carrier sponge is degraded over time, dentine replaces the degraded sponge leading to a comple

82 esistant acid phosphatase-positive cells and dentine resorption capacity in in vitro osteoclastogenes

83 resorption 2- to 3-fold in assays of lacunar dentine resorption, without affecting osteoclast viabili

84 we describe a novel, biological approach to dentine restoration that stimulates the natural formatio

85 Repetitive pressure stimulation of dentine resulted in a progressive reduction in the evoke

86 tion at the injury site enhances reactionary dentine secretion.

87 alleviating discomfort arising from cervical dentine sensitivity (CDS).

88 tic pressure (-500 to +500 mm Hg) to exposed dentine.Seventeen A-fibres (conduction velocity (CV), 10

89 II results from mutation of the bicistronic dentine sialophosphoprotein gene (DSPP ), we have tested

90 likely to lead to a loss of function of both dentine sialoprotein and dentine phosphoprotein.

91 trongly inhibited bone-resorbing function on dentine slices by mature osteoclasts and decreased 45Ca

92 on to investigate the effect of conditioning dentine slices on growth factor liberation and DPSC beha

93 nterstitial collagenase or by precoating the dentine slices with collagenase-derived gelatin peptides

94 , resorption was restored by pretreatment of dentine slices with rat interstitial collagenase or by p

95 Plating bone marrow cells onto dentine slices, a physiologic stimulus that activates os

96 on lacunae ("pits") formed on the surface of dentine slices, but it generated abnormal pits that were

97 their ability to form resorption lacunae on dentine slices.

98 nd long extracellular processes extending on dentine surface.

99 ] and bone morphogenic protein [BMP]) in the dentine that are believed to stimulate odontoblasts to s

100 and compositional alterations in enamel and dentine that coincided with elemental signatures and wit

101 ation, and point to a neural crest origin of dentine throughout the ancestral vertebrate dermal skele

102 e long-lived post-mitotic cells that secrete dentine throughout the life of the tooth.

103 imulates the natural formation of reparative dentine via the mobilisation of resident stem cells in t

104 ic, mechanical and drying stimuli to exposed dentine were investigated.