ライフサイエンスコーパス: deoxygenation

1 , warming, changes in ocean circulation, and deoxygenation).

2 t revealed loss of alpha-helical content and deoxygenation.

3 nic hydrogenation intermediates for glycerol deoxygenation.

4 with young people despite similar levels of deoxygenation.

5 rfusion is not necessarily commensurate with deoxygenation.

6 ar scar were not associated with significant deoxygenation.

7 t into an aldehyde was observed to accompany deoxygenation.

8 -methyl-2'-deoxyguanosine (3) via 2'-radical deoxygenation.

9 of abnormal hemoglobin that polymerizes upon deoxygenation.

10 ad a low membrane conductance, unaffected by deoxygenation.

11 the 4-position show higher quantum yields of deoxygenation.

12 sitized photoreaction of 7Z in benzene being deoxygenation.

13 anges in threonine phosphorylation following deoxygenation.

14 ry coordination sphere that aids in oxyanion deoxygenation.

15 photolytic deoxygenation or radical-based 2'-deoxygenation.

16 y is released from this membrane precinct by deoxygenation.

17 self-associates to dimers and tetramers upon deoxygenation.

18 ctive oxygen scavengers, but is inhibited by deoxygenation.

19 chieved by chemical doping, pressure, and/or deoxygenation.

20 lation occurred after initital, rapid muscle deoxygenation.

21 em-scale responses to abrupt, climate-forced deoxygenation.

22 tris(trimethylsilyl)silane-mediated radical deoxygenation.

23 ecessary to reduce the ecosystems impacts of deoxygenation.

24 LWHs and LANG hearts dropped steadily during deoxygenation.

25 t the sensitivity of key bacterial groups to deoxygenation.

26 Upon deoxygenation, a lower percentage of HBBAS3-transduced r

27 The combined transamination-deoxygenation activity places ColD in a class by itself.

28 plex formation as a prerequisite for the C-3 deoxygenation activity, we have carried out experiments

29 mportance of such a complex formation to the deoxygenation activity.

30 ine or mesyl chloride/triethylamine-mediated deoxygenation afforded 2H-indazoles.

31 A subsequent two-step deoxygenation affords the corresponding 1-bromo-8-methyl

32 bin to polymerise within erythrocytes during deoxygenation, altering red blood cell rheology and caus

33 oncentration of hemoglobin S and the rate of deoxygenation, among other factors.

34 s accompanied by the efficient nonreversible deoxygenation and 1-2 oxygen migration.

35 terminal hafnocene isocyanate and promoting deoxygenation and additional N-C bond formation resultin

36 formed into extended perylene derivatives by deoxygenation and aromatization with HCl/EtOH.

37 Deoxygenation and chain homologation steps complete the

38 iethylborane-methanol system used in radical deoxygenation and dehalogenation processes has been inve

39 activity of hemoglobin is modulated by heme deoxygenation and heme redox potential, with maximal act

40 cation permeability, particularly following deoxygenation and hemoglobin (Hb) polymerisation.

41 This process depends at least partly on deoxygenation and may be influenced by the presence of o

42 re of the nitride complex to CO2 resulted in deoxygenation and N-C bond formation to form isocyanate

43 thropogenic CO2 -driven ocean acidification, deoxygenation and ocean circulation.

44 s have characterized the interaction between deoxygenation and other stimuli of NKCC activity.

45 cularly striking during cycles of hemoglobin deoxygenation and oxygenation in the presence of nitrite

46 e measured by means of sampling ports in the deoxygenation and oxygenation regions.

47 b S (approximately 11 v 18 g/dL) would favor deoxygenation and polymerization of human Hb S Antilles

48 rsion to NO, a process coupled to hemoglobin deoxygenation and protonation, and evince a new, simple

49 Ocean warming, acidification, deoxygenation and reduced productivity are widely consid

50 ns an unprecedented route to interrogate the deoxygenation and reoxygenation of mitochondria, the mac

51 tion conductance was reversibly induced upon deoxygenation and was permeable to both univalent (Na+,

52 properties by allowing release of NO during deoxygenation and/or by interaction with small-molecular

53 ed stresses of warming, ocean acidification, deoxygenation, and altered food inputs.

54 , oxidatively induced reductive elimination, deoxygenation, and elimination reactions when treated wi

55 erization of hemoglobin in the red cell upon deoxygenation, and is characterized by vascular crises a

56 Double alkynylation, reductive deoxygenation, and subsequent oxidation using MnO2 furni

57 Deoxygenations are accomplished by Rh-catalyzed hydrogen

58 re, and vasorelaxant activity is "linked" to deoxygenation, as illustrated herein.

59 ytes but redistributed to the cytoplasm upon deoxygenation, as seen in human erythrocytes.

60 ns above controls, indicating that reductive deoxygenation at C-9 of a xanthone precursor does not ta

61 erturbations on 2 were also studied, namely, deoxygenation at C5 (yielding 2,5-dideoxy-beta-D-erythro

62 dibenzothiophene S-oxide in water results in deoxygenation at significantly higher quantum yields tha

63 t has been made on aliphatic primary alcohol deoxygenation by employing a ruthenium complex, with goo

64 This process involves C-2 deoxygenation, C-3 amination and methylation, C-5 epimer

65 composition (CH2O)n, modifications including deoxygenation, C-alkylation, amination, O- and N-methyla

66 The results suggest that deoxygenation causes activation of a kinase that either

67 DO diffusion from the sample stream into the deoxygenation chamber.

68 limited FENs' responses to ocean warming and deoxygenation confirms previous predictions made based s

69 be influenced by the presence of oxygenation/deoxygenation cycles and the frequency of cycling.

70 e subjected to approximately 180 oxygenation/deoxygenation cycles during 4 hours to evaluate RBC dehy

71 f the magnitude occurring during oxygenation-deoxygenation cycles had a minimal effect.

72 e involved, including, but not limited to 1) deoxygenation-dependent hemoglobin polymerization leadin

73 We find that deoxygenation-dependent rheologic processes are sufficie

74 Here, we chose to focus exclusively on deoxygenation-dependent rheologic processes in an effort

75 g a polydimethylsiloxane (PDMS) microfluidic deoxygenation device and ROXS, not only were the fluorop

76 tection strategies, including a microfluidic deoxygenation device.

77 N-Oxides are known to undergo deoxygenation during atmospheric pressure chemical ioniz

78 highly sensitive assay that exploits globin deoxygenation during respiration-catalyzed oxygen uptake

79 ment of perfusion is not sufficient to cause deoxygenation during stress.

80 Deoxygenation elevates glycolytic flux and lowers pentos

81 alcohol functions through a modified Barton deoxygenation employing hypophosphorous acid as the redu

82 ic foraminifera accompanying the most severe deoxygenation event indicates subsurface warming of up t

83 itrosothiol content, both during whole-blood deoxygenation ex vivo and during a 3-week protocol in wh

84 The smaller difference observed in the rapid deoxygenation experiment was associated with much faster

85 indicates, that faster kinetics in the rapid deoxygenation experiment were related to the initial pre

86 free magnesium concentration that occurs on deoxygenation (from 0.82 (S.D., 0.07) to 1.40 mm (S.D.,

87 scientific challenge in the field of alcohol deoxygenation has been direct catalytic sp(3) C-O defunc

88 n-specific cationic conductance activated by deoxygenation, HbS polymerisation and RBC sickling.

89 An aryl deoxygenation, however, also takes place in this overall

90 anthracenes employing a one-pot Pd-catalyzed deoxygenation/hydrogenation sequence.

91 ences between groups in duration of cerebral deoxygenation, hypotension or perioperative changes in l

92 and, along with AprD3, is responsible for 3'-deoxygenation in aminoglycoside biosynthesis.

93 exulose-3-dehydrase (E(1)) catalyzes the C-3 deoxygenation in the biosynthesis of 3,6-dideoxyhexoses

94 bin (SNO-Hb), which releases the NO group on deoxygenation in the microcirculation.

95 in the marine sulfate reservoir during ocean deoxygenation in the waning stages of the positive carbo

96 includes a minor portion of oxidant-forming deoxygenation, in contrast to previous conclusions.

97 y deoxygenated ferrous hemes, such that heme deoxygenation increases the rate of NO generation.

98 Deoxygenation-induced activation of the Gardos channel a

99 dehydration of RBCs from SCD patients - the deoxygenation-induced cation pathway (Psickle), the Ca(2

100 Many features of this deoxygenation-induced conductance (non-specificity for c

101 e o-vanillin also irreversibly inhibited the deoxygenation-induced conductance, partially at 1mM and

102 5HMF markedly reduced the deoxygenation-induced dehydration of RBCs whether in res

103 The deoxygenation-induced pathway was variable in magnitude.

104 er specificity not only during the transient deoxygenation ("initial dip") but also during the early

105 Deoxygenation is a global problem in coastal and open re

106 seudotuberculosis V, have shown that the C-3 deoxygenation is a process consisting of two enzymatic s

107 Deoxygenation is accompanied by an allosteric transition

108 This deoxygenation is accomplished via a photoinduced electro

109 This net two-step ester deoxygenation is an attractive alternative to the classi

110 Stimulation by deoxygenation is comparable with that caused by calyculi

111 that conversion of NAC to SNOAC during blood deoxygenation is necessary for the development of PAH in

112 on occurs above the LAT and that the rate of deoxygenation is sensitive to oxygen delivery.

113 -3,4-dihydroanthracen-1(2H)-one implies that deoxygenation is the first step in monodictyphenone bios

114 However, the biosynthetic mechanism of C3'-deoxygenation is unknown.

115 ction of xanthates using R3B and water (Wood deoxygenation) is presented.

116 Deoxygenations led ultimately to two new deoxy-vancomyci

117 ease of NO from SNO-Hb was not influenced by deoxygenation-mediated allosteric changes in Hb across a

118 Finally, we found that deoxygenation-mediated ATP release from isolated erythro

119 a free radical mechanism, and the subsequent deoxygenation might also benefit from the weak complexat

120 Continuous deoxygenation (N2/5% CO2) at pH 6.8 generated both ID an

121 exercise below the LAT, neither progressive deoxygenation nor lactate accumulation occurred after in

122 /dL) SS discocytes to repetitive oxygenation-deoxygenation (O-D) cycles in vitro.

123 Analysis of the photoproducts indicated the deoxygenation occurred by at least two different pH-sens

124 cohol linked to a reactive functional group, deoxygenation occurred substantially more rapidly.

125 n to either PRF or SMF increased the rate of deoxygenation occurring several min to several hours aft

126 pport the hypothesis that progressive muscle deoxygenation occurs above the LAT and that the rate of

127 While the deoxygenation of 22 proved to be problematical, the uncy

128 A subsequent two-step deoxygenation of 3 represents the first synthesis of dib

129 hypoxia activates protective mechanisms via deoxygenation of a heme moiety, triggering expression of

130 Selective deoxygenation of a primary alcohol in the presence of a

131 Formation and deoxygenation of a SNO-Hb/Band 3 protein assembly does n

132 ately recreated based on measurements during deoxygenation of a tissue phantom of mouse erythrocytes.

133 ronsted acidity in the aldolization and self-deoxygenation of acetone to isobutene.

134 reaction provides a means for the effective deoxygenation of alcohols, as demonstrated by the highly

135 lly relevant steps and site requirements for deoxygenation of alkanols and alkanals.

136 This study reports evidence for catalytic deoxygenation of alkanols, alkanals, and alkanediols on

137 C3'-deoxygenation of aminoglycosides results in their decrea

138 ctive transformations are the regioselective deoxygenation of an advanced enone intermediate and the

139 al intermediate in the thiourethane-mediated deoxygenation of an alcohol (Barton-McCombie reaction) c

140 Deoxygenation of capillary electrophoresis separation bu

141 g with its reductase (E3), catalyzes the C-3 deoxygenation of CDP-4-keto-6-deoxy-D-glucose to form th

142 xulose-3-dehydrase (E1), which catalyzes C-3 deoxygenation of CDP-4-keto-6-deoxyglucose in the biosyn

143 The C-3 deoxygenation of CDP-6-deoxy-L-threo-D-glycero-4-hexulos

144 triethylphosphite (including a rapid, direct deoxygenation of certain classes of benzoisothiazolones

145 d singlet ((1)B(1)) methylene formation from deoxygenation of CH(2)O by C ((1)D) atom as suggested by

146 A novel, mild, ecofriendly protocol for the deoxygenation of epoxides to alkenes using indium metal

147 Deoxygenation of ferret erythrocytes stimulates Na+-K+-2

148 xy-D-mannose-3-dehydrase responsible for C-3 deoxygenation of GDP-4-keto-6-deoxy-D-mannose.

149 Deoxygenation of Hb was initiated using the reducing age

150 his observation provides a mechanism for how deoxygenation of hemoglobin/myoglobin could facilitate n

151 applied independently, increased the rate of deoxygenation of human hemoglobin (Hb) in a cell-free as

152 In sickle cell disease, deoxygenation of intra-erythrocytic hemoglobin S leads t

153 Efficient depolymerization and deoxygenation of lignin while retaining the aromatic fun

154 s been developed via the palladium-catalyzed deoxygenation of mandelate esters.

155 n plane movement of cobalt which accompanies deoxygenation of myoglobin also occurs in cobalt hemoglo

156 These probes were monitored in gels after deoxygenation of oxyHb and after CO binding to deoxyHb,

157 In the presence of PtCo/NOMC, full deoxygenation of phenolic compounds and a biomass-derive

158 cid lactone, cyclization, and regioselective deoxygenation of phloroglucinol methyl ether affords res

159 been found in Nature but is obtained through deoxygenation of pukalide, the first naturally occurring

160 Third, deoxygenation of RBCs dislodges all GEs from the membran

161 Thus, cyclic deoxygenation of sickle cells under these conditions app

162 in net fluxes of Na(+) and K(+) produced by deoxygenation of SS RBCs.

163 avodoxin/flavodoxin reductase, catalyzes C-3 deoxygenation of TDP-4-keto-2,6-dideoxy-D-glucose.

164 two enzymes act sequentially to catalyze C-2 deoxygenation of TDP-4-keto-6-deoxy-D-glucose to form th

165 l)aniline and DBU in DMF; (3) hydrogenolytic deoxygenation of the "top" unit over Pearlman's catalyst

166 Stannyl radical-mediated deoxygenation of the 3'-O-TBS-2'-thionocarbamate derivat

167 the electronic changes induced by metabolic deoxygenation of the 3-amino-1,2,4-benzotriazine 1,4-dio

168 However, deoxygenation of the C(13)-hydroxyl of 16 provided the 1

169 ound has been efficiently prepared by Barton deoxygenation of the C-2- and C-14-hydroxyl groups on a

170 Deoxygenation of the C4 ketone proved difficult but was

171 ted forms (haterumalides NA, NB, and NE; via deoxygenation of the C9-hydroxyl).

172 ith p-methoxybenzaldehyde, which proceeds by deoxygenation of the carbonyl group and formation of the

173 on of the Cu coordination resulting from the deoxygenation of the CuO chains, as confirmed by first-p

174 The key step is the regioselective deoxygenation of the desired hydroxyl group as either th

175 The subsequent reductive deoxygenation of the Diels-Alder adducts with Fe2(CO)9 f

176 the presence of n-butyllithium, followed by deoxygenation of the double adducts with low-valent tita

177 of epothilone B followed by tungsten-induced deoxygenation of the epoxide moiety.

178 2-nitrobiphenyls was achieved via reductive deoxygenation of the nitro groups using a slight excess

179 Palladium-mediated deoxygenation of the resulting allylic alcohol was follo

180 Deoxygenation of the sample could be accomplished by hea

181 lectron reductive coupling and proceeds with deoxygenation of the starting enone or enal.

182 sisted in situ N-Boc-deprotection, selective deoxygenation of the xanthate ester, and lactam hydrolys

183 eir RBCs are misshapen in vivo, and in vitro deoxygenation of their blood induces 30% to 50% of the R

184 ctronic changes resulting from the metabolic deoxygenation of tirapazamine analogues might be exploit

185 Earlier experiments indicated that reductive deoxygenation of versicolorin A is not the first step.

186 ion to determine the redox potential for the deoxygenation of ZnO.

187 Deprotection (deoxygenation) of 12 was accomplished using Lawesson's r

188 f electro-organic synthesis (dehalogenation, deoxygenation) of pharmaceutically relevant building blo

189 y induced seizure causes a stronger cerebral deoxygenation on the side ipsilateral to the electrical

190 Hypoxia and CO accelerated muscle deoxygenation only for exercise above the LAT; for exerc

191 in compared with controls but no evidence of deoxygenation or hypoperfusion during vasodilatory stres

192 by a thioacetyl unit, followed by photolytic deoxygenation or radical-based 2'-deoxygenation.

193 emicals has often focused on either complete deoxygenation or the production of high-volume platform

194 on of RBCs whether in response to maintained deoxygenation or to cyclical deoxygenation/re-oxygenatio

195 osynthesis of GDP-L-colitose represent a new deoxygenation paradigm in deoxysugar biosynthesis.

196 fluence of ocean warming, acidification, and deoxygenation, poses a serious threat to marine organism

197 13 followed by the two-step Barton-McCombie deoxygenation procedure.

198 orate the mechanism proposed for the overall deoxygenation process.

199 ported conditions used in dehalogenation and deoxygenation processes.

200 s are purportedly consumed during hemoglobin deoxygenation, producing nitric oxide and coupling intra

201 d without rigorous substrate purification or deoxygenation protocols.

202 yranones and subsequent regioselective alpha-deoxygenation provides 1,3-trans-beta-hydroxy-delta-lact

203 Deoxygenation quantum yields are also less solvent depen

204 tantial FEN expansion with ocean warming and deoxygenation, rather than FEN maintenance or contractio

205 e to maintained deoxygenation or to cyclical deoxygenation/re-oxygenation.

206 r with its reductase (E3), catalyzes a novel deoxygenation reaction essential for the biosynthesis of

207 le beta-oxygen effect in the Barton-McCombie deoxygenation reaction is operating where, according to

208 ic camera flash instantaneously triggers the deoxygenation reaction of GO by photothermal heating.

209 Moreover, a revision of the mechanism of the deoxygenation reaction of xanthates using R3B and water

210 groups adjacent to the oxirane ring for the deoxygenation reaction to occur.

211 he phenyl thionoformate unit as a prelude to deoxygenation reactions of polyols.

212 O) in desulfurization, denitrogenation, and deoxygenation reactions.

213 ogenation reactions; (4) oxo-metal catalyzed deoxygenation reactions; and (5) catalyst discovery via

214 Deoxygenation/reoxygenation cycling of oxyHb in the pres

215 A cycle of deoxygenation/reoxygenation does not cause loss of NO or

216 C-O hydrogenolysis becomes the preferred deoxygenation route on Cu-based catalysts, thus avoiding

217 with the percentage of sickled cells at the deoxygenation sampling port and was observed only in the

218 rocyclic di-N-oxide that undergoes enzymatic deoxygenation selectively in the oxygen-poor (hypoxic) c

219 thylsilyl chloride followed by a Barton type deoxygenation sequence of the 3'-hydroxyl groups afforde

220 13-20a) macrocycle, an effective epoxidation/deoxygenation sequence to isomerize the C(13,14) olefin,

221 significantly increased conductance and, on deoxygenation, showed a further rise in membrane conduct

222 The exothermicity of the deoxygenation step for carbon atom reaction with methoxy

223 This eliminated the need for the deoxygenation step that is essential for existing TTA-ba

224 lowed for chain extension without additional deoxygenation steps or exogenous monomer addition.

225 had been only addressed by classic multistep deoxygenation strategies with stoichiometric reagents.

226 ves a tandem aryne Diels-Alder cycloaddition-deoxygenation strategy.

227 ible biological relevance of oxygenation and deoxygenation studies is discussed.

228 An inexpensive and quick deoxygenation system for measuring protein phosphorescen

229 responses during 2 conditions of erythrocyte deoxygenation (systemic hypoxia and graded handgrip exer

230 In addition to deoxygenation, tert-N-oxides containing an alkyl or benz

231 For both continuous and cyclic deoxygenation, TfR+ cells had a greater density increase

232 tituted DBTOs show higher quantum yields for deoxygenation than does the parent molecule, in the orde

233 With continuous deoxygenation, the density shift was decreased by inhibi

234 With cyclic deoxygenation, the density shift was decreased in an ind

235 d have provided a positive feedback on ocean deoxygenation through increased nutrient utilization and

236 (DTT) in an assay that allowed the time for deoxygenation to be controlled (from several min to seve

237 histidine swings out of the heme pocket upon deoxygenation to form a bond with a carboxyl group of a

238 osose to hydroxyhydroquinone, and subsequent deoxygenation to form hydroquinone.

239 ydration to 1,2,3,4-tetrahydroxybenzene, and deoxygenation to form pyrogallol.

240 reactants were found to increase the rate of deoxygenation to some extent, but in the presence of rea

241 laxed (R, oxygenated) conformation, and that deoxygenation to tense (T) state destabilizes the SNOHb

242 The effects of acidification and deoxygenation together were not additive.

243 hermal elimination via cyclic ortho ester or deoxygenation via cyclic thionocarbonate.

244 Photobleaching is dramatically reduced by deoxygenation via gas diffusion through porous channel w

245 the products by tert-butyl deprotection or N-deoxygenation was demonstrated.

246 blood flow during conditions of erythrocyte deoxygenation was markedly reduced in aging humans, and

247 The time course of Hb deoxygenation was observed using visible light spectrosc

248 Accessory respiratory muscle deoxygenation was present only in patients with heart fa

249 Deoxygenation was the major physiological stimulus for N

250 r at all workloads and APD reductions during deoxygenation were blunted in both LWHs and LANG hearts.

251 Stimulation by calyculin A and deoxygenation were not additive.

252 nd surprising conformational consequences of deoxygenation were revealed for one of the new compounds

253 argest signal arose from a focal increase in deoxygenation, which lasted for approximately 2 sec, con

254 as a consequence of climate change, yet how deoxygenation will affect the microbial communities that

255 with diisobutylaluminum hydride followed by deoxygenation with boron trifluoride etherate in the pre

256 for the physiologic coupling of erythrocyte deoxygenation with increased NO bioactivity in vivo.

257 Deoxygenation with reclamation of the mu-pdt parent comp

258 he silane reductant influences the degree of deoxygenation, with diethylsilane effecting the complete

259 nd effect of cell membrane stiffening during deoxygenation, with granular RBC shapes leading to the g

260 ndoles under identical conditions results in deoxygenation without cyclization.

261 addition to their utility in Barton-McCombie deoxygenations, xanthates can engage in 5-exo-trig radic