ライフサイエンスコーパス: depolarizing

1 -70 mV shifted to become barely net inward (depolarizing).

2 ective foci, and in 54.5% the foci were also depolarizing.

3 (A) receptor-mediated responses are normally depolarizing.

4 field displays a center-surround structure: depolarizing a single amacrine suppresses the visual sen

5 data suggest that GABA acquires a transient depolarizing action during recovery from UVN, which pote

6 ly suggesting that GABA acquires a transient depolarizing action in the VN during the recovery period

7 During development, GABA exerts depolarizing action on immature neurons and, acting in s

8 During development GABA exerts a depolarizing action on immature neurons.

9 le in cortical development through its early depolarizing action.

10 s importantly contribute to GDPs, due to the depolarizing actions of GABA early in development.

11 Thus, dysregulation in GABA(A) depolarizing activity delayed dendritic development and

12 on, estradiol decreased the amplitude of the depolarizing afterpotential (DAP); this effect was not t

13 ow that in flies with reduced Arr1 prolonged depolarizing afterpotential can be triggered with fewer

14 sting induction and suppression of prolonged depolarizing afterpotential.

15 locked the ability of GLP-1 agonists and the depolarizing agent KCl to potentiate this.

16 l neuronal cultures with excess K(+)Cl(-), a depolarizing agent mimicking the episode of status epile

17 eatic islets and is upregulated by beta-cell depolarizing agents.

18 eatment of cultured cells with mitochondrial depolarizing agents.

19 ree cycles), occurred when PVs and PYRs were depolarizing and entrained their membrane potential dyna

20 s channels of interest, including dephasing, depolarizing and erasure channels.

21 transiently switched from hyperpolarizing to depolarizing and excitatory.

22 At these synapses, GABA is depolarizing and exerts a bimodal control on excitabilit

23 ionally control the membrane potential using depolarizing and hyperpolarizing opsins; the ability to

24 We identified distinct roles of the depolarizing and hyperpolarizing phases of tACS in entra

25 ctance increased stepwise and gradually with depolarizing and hyperpolarizing pulses, respectively.

26 cantly by 50-150%, and the peak shifted by a depolarizing approximately 10 mV.

27 onships were shifted linearly by significant depolarizing approximately 9 and approximately 18 mV, re

28 n of light responses from hyperpolarizing to depolarizing before passing them on to ganglion cells.

29 elease by closing ATP-sensitive K+ channels, depolarizing beta cells, and opening voltage-dependent C

30 of the ERG b-wave, a component that reflects depolarizing bipolar cell (DBC) function.

31 ues molecular pathology at the photoreceptor-depolarizing bipolar cell (photoreceptor-DBC) synapse an

32 For normal function, ON or depolarizing bipolar cells (DBCs) require the G-protein-

33 11, are present at dendritic tips of retinal depolarizing bipolar cells (DBCs).

34 GABAergic current was depolarizing but inhibitory in 8.5 mM K(+), suggesting a

35 faced particle photothermally induces a cell-depolarizing capacitive current, and predicts that deliv

36 coded by the SCN5A gene, conducts the inward depolarizing cardiac Na(+) current (INa) and is vital fo

37 ffect mediated by the emergence of a rapidly depolarizing cell population, and the expression of hERG

38 and predicted that the gradient between the depolarizing cells at the distal expansion and the repol

39 be searched, when decoherence is modelled by depolarizing channels' deleterious effects imposed on th

40 to have disease-causing mutations in cardiac depolarizing channels.

41 internal reflectivity, presence of internal depolarizing characteristics, and presence of overlying

42 leotide-gated (CNG) channel and stimulates a depolarizing chloride current by opening the olfactory C

43 er direct control, we used densely-expressed depolarizing (ChR2) or hyperpolarizing (eArch3.0, eNpHR3

44 Hence, despite the well known depolarizing Cl(-) equilibrium potential of neonatal hip

45 ropose that, even in the presence of a local depolarizing Cl(-) gradient, HCO3(-) efflux through GABA

46 g that presynaptic NMDARs may function under depolarizing conditions throughout life.

47 consistent with the idea that under extreme depolarizing conditions, the biophysical difference betw

48 Independently, phasic DA activated a slow depolarizing conductance and the late burst through a D1

49 ogeneous medium internal reflectivity and no depolarizing contents (55.3% of drusen).

50 e-type releaser at DAT that evoked an inward depolarizing current and calcium influx, whereas other a

51 ts due to a severe reduction of a muscarinic depolarizing current and M1 receptor internalization.

52 um-selective ion channel responsible for the depolarizing current and maintenance of the action poten

53 activation might cause a sharp escalation in depolarizing current and underlie the steep initial rise

54 the number of action potentials evoked by a depolarizing current at 2X rheobase in neurons from CCD

55 athogeneses were likely to have mutations in depolarizing current channels.

56 s can fire single action potentials (APs) to depolarizing current commands, but are unable to dischar

57 es the action potential waveform by reducing depolarizing current during the plateau phase of the act

58 dium current (I(Na)), which provides a rapid depolarizing current during the upstroke of the action p

59 e sodium current (INa) that provides a rapid depolarizing current during the upstroke of the action p

60 ing sodium channel that conducts a transient depolarizing current in multidendritic sensory neurons o

61 Single pulses or a train of pulses of depolarizing current injected into an ET cell evoked sup

62 re quiescent or made to fire at low rates by depolarizing current injection, light-induced activation

63 the voltage-response to hyperpolarizing and depolarizing current injection.

64 The magnitude of [Ca(2+)]i reduction during depolarizing current injections correlated with the ampl

65 The maximum spike frequency evoked by depolarizing current injections in Scn8a(N1768D/+) CA1,

66 e majority of cells preset at -80 mV, 500 ms depolarizing current injections to cells led to a brief

67 lar, nonaccommodating spiking in response to depolarizing current injections, and an absence of plate

68 response to small, but not large, amplitude depolarizing current injections, whereas firing rates we

69 ippocampal neurons in response to repetitive depolarizing current injections.

70 F also attenuated APD evoked by injection of depolarizing current into second-order neurons, indicati

71 re performed and, following the injection of depolarizing current into the dendrites, layer 5 neurons

72 y quantifying the impact of an infinitesimal depolarizing current pulse on the time of occurrence of

73 l Pv interneuron activation by intracellular depolarizing current pulses.

74 fficult to determine the ionic mechanisms of depolarizing current since potassium transients are chal

75 persistent firing that is induced by a brief depolarizing current stimulus in the presence of muscari

76 When driven by various forms of depolarizing current stimulus, Re neurons display consid

77 ion of duck TG neurons evokes high-amplitude depolarizing current with a low threshold of activation,

78 ng pattern, and the rest respond to injected depolarizing current with a regular-spiking pattern.

79 esponse increased indefinitely with injected depolarizing current, but reached saturation with chemic

80 tion of an M1-coupled, pirenzepine-sensitive depolarizing current, which appeared to be, at least in

81 A receptor activation initiated a secondary, depolarizing current.

82 sponses to hyperpolarizing (P < 0.00007) and depolarizing currents (P < 0.001) in threshold electroto

83 edictions and experimental results: net soma depolarizing currents increased choice hysteresis, while

84 In contrast, with stronger depolarizing currents, eliciting firing above approximat

85 sed in Chinese hamster ovary cells, into the depolarizing direction and significantly increases their

86 s, PAG shifted the transwall gradient in the depolarizing direction.

87 NOS-KO mice, the gradient was shifted in the depolarizing direction.

88 ATP release could be elicited by depolarizing DKO Receptor cells with KCl, suggesting tha

89 channels seem to provide the major nonlinear depolarizing drive in thin dendrites, even allowing full

90 citability, we mimicked the mutant channel's depolarizing effect by current injection to produce equi

91 Moreover, their combined depolarizing effect enables the fast quantal AMPAR compo

92 patch-clamp recordings demonstrated that the depolarizing effect of 5-HT on PVINs was mediated by 5-H

93 The depolarizing effect of GLP-1 on electrical activity was

94 est that GABA controls STDP polarity through depolarizing effects at distal dendrites of striatal out

95 The depolarizing effects of GABA are strongest at the soma o

96 lopmentally regulated and cell-type-specific depolarizing effects on auditory brainstem neurons of Mo

97 no such effect was observed when placing the depolarizing electrode over lateral PFC.

98 We placed the soma depolarizing electrode over medial frontal PFC.

99 ithin the isthmus enabled retrograde flow of depolarizing electrotonic current to trigger EADs and re

100 ic ventral posterior medial neurons and with depolarizing events in the posterior nucleus neurons.

101 to OPA1 cleavage induced in CGNs by removing depolarizing extracellular potassium (5K apoptotic condi

102 ernal depolarizing structures and associated depolarizing foci.

103 s in adolescent and adult rat DGCs are still depolarizing from rest.

104 These include the depolarizing 'funny current' (If ) and the sodium-calciu

105 The neurosteroid estradiol potently augments depolarizing GABA action in the immature hypothalamus by

106 ur findings show that early post-SE abnormal depolarizing GABA and p75(NTR) signaling fosters a long-

107 evelopment, yet the mechanisms that regulate depolarizing GABA are not well understood.

108 ing the seizure significantly attenuated the depolarizing GABA(A)R responses and also reduced the ext

109 As depolarizing GABA(A)R signaling has been implicated in s

110 ession, the adenosine-induced attenuation of depolarizing GABA(A)R signaling may represent an importa

111 may be critical factors in the regulation of depolarizing GABA-mediated processes in the developing b

112 s of the K(+)/Cl(-) cotransporter KCC2 and a depolarizing GABAA receptor-mediated synaptic component

113 We found that depolarizing GABAergic and glutamatergic currents act in

114 A similar depolarizing GABAergic plexus exists in the developing h

115 monstrated that chandelier cells can produce depolarizing GABAergic PSPs, occasionally driving postsy

116 increase in glutamatergic input and requires depolarizing GABAergic transmission and NMDA receptor ac

117 fuse intracerebrally a specific inhibitor of depolarizing GABAergic transmission as well as a functio

118 rewiring of excitatory circuits, an abnormal depolarizing gamma-aminobutyric acidergic (GABAergic) dr

119 ent individual principal cells from strongly depolarizing granule cells, which likely discharge in re

120 , damaging the tip links of hair bundles, or depolarizing hair cells eliminated amplification.

121 13R expression is uniquely associated with a depolarizing, HCO3(-) independent, Cl(-) -conductance in

122 abilization could also be elicited by single depolarizing/hyperpolarizing pulses of very high field s

123 ointestinal physiology because they transmit depolarizing impulses in enteric neurons, thereby enabli

124 rpolarizing in CA1 principal cells (PCs) but depolarizing in dentate gyrus (DG) PCs.

125 ge from hyperpolarizing in intact neurons to depolarizing in injured neurons.

126 and miR-34c, which subsequently targeted key depolarizing (INa) and repolarizing (Ito) currents alter

127 hanotransduction currents (I(MET)) provide a depolarizing influence to the resting potential.

128 easing activity during behavior and directly depolarizing inhibitory cells.

129 ounted for largely by granule cells, receive depolarizing input from M/T dendrites and in turn inhibi

130 athway provides on average 3.7-fold stronger depolarizing input to layer 2/3 inhibitory PV neurons th

131 li), persistent spiking in response to brief depolarizing inputs and the relationship between firing

132 In the FB(LM-->V1) pathway, depolarizing inputs to layer 2/3 PV neurons and Pyr cell

133 aptic activation of mGluR5 acts primarily by depolarizing interneurons and evoking widespread dendrit

134 g to a loss of ion selectivity and gain of a depolarizing inward cation conductance.

135 A depolarizing 'leak' current supports this firing pattern

136 atrial cardiomyocyte monolayers expressing a depolarizing light-gated ion channel (Ca(2+)-translocati

137 We demonstrate that the depolarizing M-current conducted by Kv7 channel is signi

138 al of 30.5% of the drusen exhibited internal depolarizing material; 0.3% presented overlying hyperref

139 Despite depolarizing MCs directly, the net effect of nAChR activ

140 rrent clamp, block of BKCa current increased depolarizing membrane potential excursions, raising the

141 amped horizontal cells, BKCa channels subdue depolarizing membrane potential excursions, reduce the a

142 It is triggered by depolarizing mitochondria or promoting PTP openings.

143 by potent inhalation anesthetics and/or the depolarizing muscle relaxant succinylcholine in malignan

144 bative: e.g., by intentionally polarizing or depolarizing one spin species while detecting the respon

145 ience research through their use as membrane-depolarizing optogenetic tools for targeted photoactivat

146 manipulated the activity of CI1 by injecting depolarizing or hyperpolarizing current or killing the c

147 post-trial activity decay through simulated depolarizing or hyperpolarizing network stimulation.

148 With mildly depolarizing or hyperpolarizing pulses just above thresh

149 It is concluded that, in these beta-cells, depolarizing oscillations in Deltapsi(p) are not initiat

150 Depolarizing PCs initiated a long-lasting increase in GA

151 Depolarizing pFL neurons produced active expiration at r

152 cal or genetic ablation of I(h) broadens the depolarizing phase of afferent synaptic waveforms by hyp

153 shallow hyperpolarizing phase followed by a depolarizing phase of briefer duration.

154 odium (Nav) channels are responsible for the depolarizing phase of the action potential in most nerve

155 e proteins that are responsible for the fast depolarizing phase of the action potential in nerve and

156 This result together with the subsequent depolarizing phase provides a signal that is energetical

157 Here we report that the large depolarizing plateau potential that underlies the epilep

158 may hold even greater potential as tools for depolarizing political debates and resolving policy disp

159 At a depolarizing potential of -5 mV, the ICa,L current densi

160 l neurons between two SLEs correlated with a depolarizing potential.

161 ntaneous network events known as field giant depolarizing potentials (fGDPs) and of the unit activity

162 Two primary burst types were studied: giant depolarizing potentials (GDPs) and spontaneous intericta

163 this activity is observed in vitro as giant depolarizing potentials (GDPs) during the first postnata

164 ting in synergy with glutamate, drives giant depolarizing potentials (GDPs) in the hippocampal networ

165 taneous network events, referred to as giant depolarizing potentials (GDPs) in the hippocampus.

166 Spontaneous giant depolarizing potentials (GDPs) were first identified wit

167 y, SPAs are replaced by synapse-driven giant depolarizing potentials (GDPs).

168 ated nicotinic ACh receptor (nAChR)-mediated depolarizing potentials and muscarinic ACh receptor (mAC

169 Our analysis reveals that these giant depolarizing potentials are mediated by the activation o

170 rticocallosal neurons lacking mAChR-mediated depolarizing potentials did not show persistent firing.

171 These prolonged depolarizing potentials generated persistent firing in c

172 rons, ACh generated prolonged mAChR-mediated depolarizing potentials in corticocollicular neurons.

173 the conductance-voltage relationship to more depolarizing potentials with a half-maximal effective co

174 re hyperexcitable and generated long-lasting depolarizing potentials with bursts of action potentials

175 im, calcium transients associated with giant depolarizing potentials, a hallmark of developmental net

176 pening with FL(4)-like voltage dependence at depolarizing potentials, but all four sensors are requir

177 olonged critical period permissive for giant depolarizing potentials.

178 ous MN activity is driven by recurrent giant depolarizing potentials.

179 and voltage, so that opening is promoted by depolarizing potentials.

180 rectification because of polyamine block at depolarizing potentials.

181 tiated delayed rectifier Kv1 channels at low depolarizing potentials.

182 ous activities appeared in the form of giant depolarizing potentials.

183 s, ACh release also generated nAChR-mediated depolarizing potentials.

184 and slowing of deactivation in response to a depolarizing prepulse.

185 inhibition was voltage-dependent, and strong depolarizing prepulses attenuated Hm-3 activity.

186 time course of recovery from short and long depolarizing prepulses, which, under drug-free condition

187 ve membrane potentials but only after strong depolarizing prepulses.

188 on was voltage-independent and unaffected by depolarizing prepulses.

189 oltage-dependent and transiently relieved by depolarizing prepulses.

190 ChR2 elevating the probability of release by depolarizing presynaptic boutons.

191 entries using Grover's QSA at an aggressive depolarizing probability of 10(-3), the success probabil

192 Thalamic neurons respond to a brief depolarizing pulse with a burst of action potentials; ho

193 Using long (20 s) depolarizing pulses both gating modes were activated, an

194 The sADPs generated by repeated depolarizing pulses summed to promote a plateau potentia

195 e receptor agonist (4-chloro-meta-cresol) or depolarizing pulses were used.

196 -VSD deactivation kinetics were modulated by depolarizing pulses with durations in the intermediate t

197 Finally, during a train of depolarizing pulses, paired pulse plasticity was signifi

198 cells of Ca(2+) alternans produced by small depolarizing pulses.

199 peting attractor network models predict slow depolarizing ramps.

200 in EC coupling, and represents an intrinsic depolarizing reserve that contributes to excitation.

201 Depolarizing responses in VIP or PV BCs resulted in incr

202 d Go-opsin1 coexpressed with two r-opsins in depolarizing rhabdomeric photoreceptor cells in the pigm

203 e polarized than control cells, confirming a depolarizing role of TWIK1 in kidney and pancreatic cell

204 rked changes in the hyperpolarization-evoked depolarizing sag and rebound firing across these groups.

205 Ih was identified to be responsible for the depolarizing sag and was increased across OVX --> diestr

206 fterhyperpolarization, firing frequency, and depolarizing sag), whereas the differences in the first

207 rebound or post-stimulation recovery, and no depolarizing sag.

208 l mutations (W1775R and L1831X) exhibiting a depolarizing shift in channel activation.

209 Application of VU0463271 caused a reversible depolarizing shift in E(GABA) values and increased spiki

210 According to computational modeling, a depolarizing shift in GABA reversal potential (EGABA) an

211 uced membrane hyperpolarization and caused a depolarizing shift in GABA reversal potential of dorsal

212 ificant increase in the I(h) amplitude and a depolarizing shift in I(h) activation curve.

213 v)1.7 activation, whereas beta(1) produced a depolarizing shift in inactivation and faster recovery.

214 shold voltage for activation, and produced a depolarizing shift in inactivation in wild-type - but no

215 Whether the depolarizing shift in resting potential and enhanced spo

216 indicated that this increase is caused by a depolarizing shift in the activation curve of the native

217 physically distinct K(+) currents revealed a depolarizing shift in the activation of a rapidly inacti

218 es glycine-mediated inhibition and induces a depolarizing shift in the reversal potential of glycine-

219 aturating concentrations, SNX-482 produced a depolarizing shift in the voltage dependence of activati

220 of kinetics, and, most surprisingly, a 30 mV depolarizing shift in the voltage dependence of activati

221 A mere 5 mV depolarizing shift in the voltage dependence of activati

222 CCt induced a depolarizing shift in the voltage dependence of both CaV

223 creased current density was accompanied by a depolarizing shift in the voltage dependence of channel

224 rent, incomplete channel inactivation, and a depolarizing shift in the voltage dependence of steady-s

225 strate that Scn1b null DRG neurons exhibit a depolarizing shift in the voltage dependence of TTX-S I(

226 SNAP caused a depolarizing shift in voltage-dependent N-type channel a

227 ming, and larger ramp currents, override the depolarizing shift of activation, to produce hyperexcita

228 urrent amplitudes (3 pore mutations) or by a depolarizing shift of the activation curve (2 voltage se

229 fter spinal cord injury (SCI) resulting in a depolarizing shift of the chloride equilibrium potential

230 Maximal depolarizing shift of the If activation curve induced by

231 d with loss-of-function effects, including a depolarizing shift of voltage-dependent activation or a

232 )) of PVN presympathetic neurons undergoes a depolarizing shift that diminishes GABA inhibition in sp

233 led increased spontaneous firing, paroxysmal-depolarizing-shift-like complexes, and an increased firi

234 isolated from ST3Gal4(-/-) mice demonstrated depolarizing shifts in activation gating of the transien

235 Micromolar DA produces immediate depolarizing shifts in the voltage dependence of LP I(A)

236 Non-depolarizing shunts of 3-10 nS converted cells from clas

237 esting revealed disease-causing mutations in depolarizing sodium (SCN5A) or calcium (CaCNB2b) channel

238 tern elicited in layer 5 neurons by steps of depolarizing somatic current, even though the firing rat

239 out preventing further prolongation by brief depolarizing somatic prepulses.

240 ulse potentiation," in which activation by a depolarizing step facilitates activation in a subsequent

241 reported that the K current in response to a depolarizing step to ENa was delayed if the step was pre

242 We found that application of brief depolarizing steps (<100 ms) to cones evoked exocytosis

243 age-dependence of channel activation so that depolarizing steps evoke larger sodium currents.

244 recordings from mouse PFC pyramidal neurons, depolarizing steps significantly suppressed IPSCs induce

245 Trains of depolarizing steps to the hair cell were used to elicit

246 ion, rather than to the timing of subsequent depolarizing steps, suggesting that cholinergic signal t

247 During depolarizing stimulation, newly appearing vesicles appro

248 CO2/H+ changes), in the absence of external depolarizing stimulation, showed no signs of postinhibit

249 unced slowing of current inactivation during depolarizing stimuli (p.G407R).

250 ormally governs cortical neuron responses to depolarizing stimuli by opposing prolonged discharges an

251 porting persistent firing modes triggered by depolarizing stimuli following cholinergic receptor acti

252 T-channels switched burst firing with lower depolarizing stimuli to regular spiking, and fully aboli

253 entate granule neurons in response to strong depolarizing stimuli was also observed.

254 ted modest transient electrical responses to depolarizing stimuli, revealing the potential for circad

255 t KCNQ channels, which are activated only by depolarizing stimuli, the presynaptic channels began to

256 ted modest transient electrical responses to depolarizing stimuli.

257 granules and are differentially activated by depolarizing stimuli.

258 d secrete it in response to glucose or other depolarizing stimuli.

259 unds were able to block Ca(2+) entry after a depolarizing stimulus and showed an improved Cav1.3/Cav1

260 rotein densin and CaMKII and that outlasts a depolarizing stimulus by seconds.

261 il current of up to 8 s duration following a depolarizing stimulus in both tsA-201 cells and male rat

262 enings that can last for seconds following a depolarizing stimulus train.

263 d in relocation of the AIS of DGCs without a depolarizing stimulus.

264 moting synchronous fusion of SVs driven by a depolarizing stimulus.

265 utward tail current of up to 8 s following a depolarizing stimulus.

266 litation of channel activity that outlasts a depolarizing stimulus.

267 n scheme, including the presence of internal depolarizing structures and associated depolarizing foci

268 rk models in which neurons receive sustained depolarizing synaptic input during a field crossing, suc

269 peak spike rates, and were more sensitive to depolarizing synaptic input.

270 n contrast, PID ripples were associated with depolarizing synaptic inputs frequently reaching the thr

271 totic capacitance increases evoked by 200-ms depolarizing test steps, whereas FALI more strongly inhi

272 ide-gated (HCN) channels, and contributes to depolarizing the afferent to potentials where a single E

273 y of ENaCs, which augments synaptic drive by depolarizing the basal membrane potential close to the a

274 to heat, which changes membrane capacitance, depolarizing the cell and eliciting action potentials.

275 ctivity of sarcolemmal Na(+)-Ca(2+) exchange depolarizing the cell membrane.

276 Depolarizing the dorsal lineages in which these cells re

277 ErbB4-expressing interneuron excitability by depolarizing the firing threshold; neurons treated with

278 ong the GnRH neuron projection is capable of depolarizing the membrane potential and initiating actio

279 are biased toward open/inactivated states by depolarizing the membrane potential under voltage-clamp

280 on potential firing to current injection and depolarizing the membrane potential.

281 or ion channels mediate neurotransmission by depolarizing the postsynaptic membrane at the neuromuscu

282 oss-linked 300 kDa increased excitability by depolarizing the resting membrane potential, and decreas

283 ectrical capacitance of the plasma membrane, depolarizing the target cell.

284 es IP3R up-regulation during hypertension by depolarizing the VSM cell membrane.

285 l enhancement is accomplished by selectively depolarizing the xenon within a cage molecule which, upo

286 cted selectively to increase their activity, depolarizing these neurons and increasing their firing r

287 An accompanying increase in depolarizing threshold electrotonus at 90 to 100 millise

288 alteration in recovery cycle parameters and depolarizing threshold electrotonus.

289 ts transiently switched their direction from depolarizing to hyperpolarizing as a result of neuronal

290 al pyramidal neurons undergoes a switch from depolarizing to hyperpolarizing during early neuronal de

291 We found that the timing of the switch from depolarizing to hyperpolarizing GABA is delayed in the c

292 irectionally selective (DS) light responses, depolarizing to stimuli that move centrifugally away fro

293 Remarkably, this depolarizing tonic conductance was strongly inhibitory p

294 A 5 Hz, 1 min train of depolarizing voltage steps elicited voltage-gated Ca(2+)

295 ed that strong hyperpolarization preceding a depolarizing voltage-clamp pulse delayed the rise of the

296 Being activated by depolarizing voltages and increases in cytoplasmic Ca(2+

297 JZTx-27 was more efficacious at weaker depolarizing voltages and significantly slowed the activ

298 is not dependent on the level of maturation (depolarizing vs. hyperpolarizing) of postsynaptic GABAA

299 AP rise times and conduction velocity as the depolarizing wavefront approaches the epicardial surface

300 V1 on ganglion cells from hyperpolarizing to depolarizing, which was also transient.