ライフサイエンスコーパス: depolarizing pulse

1 generated upon repolarization after a large depolarizing pulse.

2 d cells remained unattenuated throughout the depolarizing pulse.

3 e same time course as the current during the depolarizing pulse.

4 does not inactivate appreciably during short depolarizing pulses.

5 50 ms pulses, with significant resistance to depolarizing pulses.

6 comparable with that triggered by a train of depolarizing pulses.

7 PGN fired on average only 1.4 spikes during depolarizing pulses.

8 e sustained Na+ currents at the end of 30-ms depolarizing pulses.

9 ivation that channels rapidly undergo during depolarizing pulses.

10 onship identical to that obtained for single depolarizing pulses.

11 ted patch mode and stimulated with trains of depolarizing pulses.

12 cells of Ca(2+) alternans produced by small depolarizing pulses.

13 monitor exocytosis in response to trains of depolarizing pulses.

14 in the releasable pool) was not affected by depolarizing pulses.

15 ancy between the currents during the initial depolarizing pulse and the tail current.

16 stsynaptic currents, pattern of discharge to depolarizing pulses and current-voltage relationships.

17 lar free Ca2+ in turtle hair cells evoked by depolarizing pulses and has delineated factors affecting

18 col, uses currents during a moderately large depolarizing pulse, and the other uses tail currents aft

19 For short 20 ms depolarizing pulses, and interpulse intervals between 15

20 change in fluorescence can faithfully report depolarizing pulses as short as 2 ms.

21 cilitation was observed even during a single depolarizing pulse, as confirmed by two-pulse experiment

22 Using long (20 s) depolarizing pulses both gating modes were activated, an

23 single channels open only once or twice per depolarizing pulse, but in the slow mode the channels de

24 ed in smaller exocytotic responses to single depolarizing pulses, but the normal relationship between

25 ail currents depended on the duration of the depolarizing pulse, consistent with a rise in intracellu

26 - 0.004 nA); (iv) firing of APs throughout a depolarizing pulse (duration <= 1 s) and one to four APs

27 In the presence of 4-aminopyridine, depolarizing pulses evoked transient outward currents an

28 Single step depolarizations or trains of depolarizing pulses evoked voltage-dependent, inward Ca2

29 mediating DAPs (IDAP), evoked by three brief depolarizing pulses, had a peak of 17 +/- 1 pA (mean +/-

30 Exocytotic events occur principally during depolarizing pulses, i.e., events are "stimulus-coupled"

31 activation time constant (tau(act))] during depolarizing pulses; (iii) slower deactivation [larger d

32 current was induced progressively after each depolarizing pulse in a train of stimuli, and this Na+ c

33 mode was maintained for the duration of the depolarizing pulse in the presence of the beta2a subunit

34 ed with single depolarizations and trains of depolarizing pulses in whole cell perforated patch clamp

35 id decay became shorter as the length of the depolarizing pulse increased but was unaffected by chang

36 f deactivation slowed as the duration of the depolarizing pulse increased.

37 eopenings for all three mutants during 40-ms depolarizing pulses, indicating a substantial impairment

38 A depolarizing pulse induced a release permeability with a

39 , and the decline in [Ca2+]i at the end of a depolarizing pulse is three to four times faster in toni

40 Finally, during a train of depolarizing pulses, paired pulse plasticity was signifi

41 Previous work has shown that small depolarizing pulses produce a beat to beat alternation i

42 lar myocytes, stimulating with small (20 mV) depolarizing pulses produced alternans of the amplitude

43 Depolarizing pulses produced rapid increases in capacita

44 However, after a brief (50 ms) depolarizing pulse, recovery from lidocaine block is sim

45 As frequencies of depolarizing pulses rose from 2 to 20 Hz, the times to p

46 e-pulse of a few seconds or a burst of brief depolarizing pulses selectively augmented the subsequent

47 results imply excitation by hyperpolarizing-depolarizing pulse sequences at two separate sites.

48 The indo-1 transient elicited by an 800 ms depolarizing pulse showed a rapid initial rise which was

49 Steady-state IKr during depolarizing pulses showed characteristic inward rectifi

50 otic Cm rise (delta Cm,s) that outlasted the depolarizing pulse stimulus.

51 Depolarizing pulses subthreshold to activating a Ca2+ sp

52 The sADPs generated by repeated depolarizing pulses summed to promote a plateau potentia

53 very is also dependent on the voltage of the depolarizing pulse that induces the inactivation, consis

54 es its current amplitudes elicited by strong depolarizing pulses that maximally activate the channels

55 rge elevation in [Ca2+]i at the start of the depolarizing pulse, there was an increase in I beta, the

56 Depolarizing pulses to 0 mV elicited large Ca2+ transien

57 Unitary current sweeps were evoked by 300-ms depolarizing pulses to 0 mV, from a holding potential of

58 During depolarizing pulses to the Cx45-expressing cell, Cx43 co

59 Depolarizing pulse trains also elicited a rapid increase

60 unt of total Ca2+ entry during a single long depolarizing pulse usually evoked a much larger secretor

61 verage 12.3 +/- 1.4 spikes during a 500 msec depolarizing pulse) versus phasic firing (1.2 +/- 0.2 sp

62 'Decay' of release during a depolarizing pulse was defined as the difference between

63 As the duration of a depolarizing pulse was increased (range 0.32-10 ms), the

64 As the amplitude of the depolarizing pulse was increased from 10 to 30 mV the ma

65 the decaying phase of Na+ currents during a depolarizing pulse was significantly accelerated by all

66 The amount of Ca2+ releasable by depolarizing pulses was always equal to the amount of Ca

67 Ca2+ channel inactivation during depolarizing pulses was primarily voltage-dependent.

68 was no longer seen when the duration of the depolarizing pulses was reduced to 100 ms, but was clear

69 TX-resistant action potentials during 600 ms depolarizing pulses was significantly increased time dep

70 When the depolarizing pulses were applied at 3 Hz to mimic normal

71 on were observed when one to three preceding depolarizing pulses were applied, although there was a t

72 When pairs of depolarizing pulses were applied, the increase in [Ca2+]

73 To investigate further the state dependence, depolarizing pulses were used to inactivate the channels

74 e receptor agonist (4-chloro-meta-cresol) or depolarizing pulses were used.

75 ivation, hyperpolarization and diminution of depolarizing pulses, were simulated from the experimenta

76 ndritic Ca2+ spikes evoked by suprathreshold depolarizing pulses, which could be terminated by superi

77 Thalamic neurons respond to a brief depolarizing pulse with a burst of action potentials; ho

78 red from the inactivation induced by a 60 ms depolarizing pulse with time constants of 1.6 ms (91 %)

79 -VSD deactivation kinetics were modulated by depolarizing pulses with durations in the intermediate t