ライフサイエンスコーパス: depolymerization

1 e disassembly rate (corresponding to F-actin depolymerization).

2 inutes via combined fibril fragmentation and depolymerization.

3 elongation, severing, and WH2 motif-mediated depolymerization.

4 ound to actin filaments stabilizes them from depolymerization.

5 plastic deformation and reprocessing without depolymerization.

6 cooperate to stabilize filaments by slowing depolymerization.

7 an also sever filaments and accelerate their depolymerization.

8 ers whose disassembly is maintained by actin depolymerization.

9 lkene acid structure formed during enzymatic depolymerization.

10 een LPMO and hydrolytic enzymes in cellulose depolymerization.

11 (2+)-catalyzed Fenton-type and photochemical depolymerization.

12 facilitate tracking during rapid microtubule depolymerization.

13 e of the mitotic checkpoint upon microtubule depolymerization.

14 and protect them against kinesin-13-induced depolymerization.

15 ement to microtubule (MT) polymerization and depolymerization.

16 re movement coupled to MT polymerization and depolymerization.

17 t synergy with hydrolytic enzymes in biomass depolymerization.

18 actor of the efficiency of enzymatic biomass depolymerization.

19 volved in the exolytic mechanism of alginate depolymerization.

20 ty to protect microtubules from cold-induced depolymerization.

21 similar ER phenotype as observed after actin depolymerization.

22 ds to open interfaces that are more prone to depolymerization.

23 duced at the kinetochore and coupled with MT depolymerization.

24 tant cellulosomal component during cellulose depolymerization.

25 Leptin signaling also leads to F-actin depolymerization.

26 s accessory, redox-active enzymes for lignin depolymerization.

27 to prevent further actin polymerization and depolymerization.

28 e vs. 0.6 +/- 0.2 pN/mum after partial actin depolymerization.

29 mediates smooth muscle relaxation via actin depolymerization.

30 higher amounts of flavan-3-ols were used for depolymerization.

31 erest due to its ease of synthesis and rapid depolymerization.

32 that participates in both polymerization and depolymerization.

33 hese domains function independently in actin depolymerization.

34 g domain and delays dilution-induced F-actin depolymerization.

35 the C4 carbocations from procyanidins during depolymerization.

36 try progressively altered our views of actin depolymerization.

37 myosin light chain phosphorylation and actin depolymerization.

38 y RSK2 reduced stathmin-mediated microtubule depolymerization.

39 ia actomyosin contraction coupled with actin depolymerization.

40 fulfill a critical targeting function in PCW depolymerization.

41 egulated in part by actin polymerization and depolymerization.

42 chanism involving Kif24-mediated microtubule depolymerization.

43 Microtubule depolymerization abolished uptake of complement-opsonize

44 g CMTs at crossover sites and leads to their depolymerization about 85% of the time.

45 ends and is critical for polymerization and depolymerization activities.

46 ctivity, and seven proteins showed polyester depolymerization activity against polylactic acid and po

47 MCAK microtubule depolymerization activity is inhibited by Aurora B-depen

48 Cofilin-1-severing/depolymerization activity is negatively regulated by pho

49 a mechanism by which the robust microtubule depolymerization activity of kinesin-13s can be rapidly

50 sensitivity of the mutant G1-G3 for F-actin depolymerization activity, although the F-actin-binding

51 ith microtubules and reduces its microtubule depolymerization activity.

52 Reductive depolymerization after cellular uptake should then relea

53 s model of filament formation, bundling, and depolymerization after GTP hydrolysis, which involves a

54 Moreover, we find that actin depolymerization and AMPA receptor exocytosis are regula

55 ensional growth, latrunculin-A-induced actin depolymerization and apoptosis, and cell line transfecti

56 Efficient depolymerization and deoxygenation of lignin while retai

57 cofilin had no effect on F-actin binding and depolymerization and did not influence the cofilin phosp

58 Depolymerization and differential scanning calorimetry a

59 -actin bands develop increased resistance to depolymerization and exceptional stability that parallel

60 trunculin B, a reagent known to induce actin depolymerization and impair bulk and ultrafast endocytos

61 and leading to faster glucose-induced actin depolymerization and increased insulin release.

62 Microtubule depolymerization and kinesin-related motors contribute t

63 Calcium acts by promoting actin depolymerization and localizing actin polymerization and

64 underlies Golgi dispersal during microtubule depolymerization and mitosis.

65 ation, negative regulation of actin filament depolymerization and negative regulation of protein comp

66 n of valuable products emanating from lignin depolymerization and the successful execution of such st

67 s recapitulates all aspects of reversible MT depolymerization and transient formation of +TIPs bars.

68 vage method, its application to aspen lignin depolymerization, and mechanistic insights into the reac

69 ls where aging or mechanical damage triggers depolymerization, and orthogonal conditions regenerate t

70 e expression by leptin is dependent on actin depolymerization, and pharmacologically induced actin de

71 sm of action is determined to be microtubule depolymerization, and the compound is shown to not signi

72 Polymerization and depolymerization are especially important for gliding mo

73 with either lower temperature or microtubule depolymerization are known to decrease axonal transport.

74 by establishing colcemid-induced microtubule depolymerization as a sensitive assay, we examined the c

75 investigations into lignin's degradation and depolymerization as related to its stereochemical consti

76 both rates of microtubule polymerization and depolymerization as well as by reducing the frequency of

77 t fascin-2 crosslinks function to slow actin depolymerization at stereocilia tips to maintain stereoc

78 tions of keratin filament polymerization and depolymerization at subcellular resolution.

79 es with short K-fibers was uncoupled from MT depolymerization at the kinetochore.

80 o one-dimensional diffusion (ODD) and induce depolymerization at the MT ends.

81 Actin depolymerization blocks the increase in spEPSC amplitude

82 crotubules from cold- and nocodazole-induced depolymerization but the molecular and structure determi

83 est that SEPT9 protects actin filaments from depolymerization by cofilin and myosin and indicate a me

84 significantly reduces the extent of F-actin depolymerization by cofilin.

85 e endo-1,6-beta-glucanase in 1,6-beta-glucan depolymerization by deleting bt3312, which prevented the

86 Consistently, microtubule depolymerization by nocodazole blocks granule withdrawal

87 wn cells also display enhanced resistance to depolymerization by nocodazole.

88 bulin curvature-sensing model of microtubule depolymerization by the budding yeast kinesin-8, Kip3.

89 Growing microtubules are protected from depolymerization by the presence of a GTP or GDP/Pi cap.

90 Its depolymerization can be accomplished through hydrogenoly

91 cell walls, to be more amenable to chemical depolymerization can lower the energy required for indus

92 l ER, whereas locally increasing microtubule depolymerization causes exaggerated asymmetric spindle p

93 Following cyclin B degradation, ipMT depolymerization ceases so the sliding ipMTs can push th

94 s required, and there is evidence that actin depolymerization contributes to contraction.

95 ex is required for a distinct substep of the depolymerization-coupled pulling mechanism.

96 Depletion of either SNX27 or VPS35 or actin depolymerization decreased the rate of PTHR recycling fo

97 monstrate novel derivatization chemistry for depolymerization/desulfation and alkylation of HS based

98 perties, heparin source material and mode of depolymerization, disaccharide building blocks, fragment

99 lls, consistent with rapid MT polymerization/depolymerization during cell proliferation.

100 in a distinctly polar manner to catastrophic depolymerization (dynamic instability) both in vitro and

101 it could be hypothesized that polymerization-depolymerization dynamics may be an additional signal th

102 Mechanistically, cold-induced MT depolymerization experiments demonstrated a hyper-stabil

103 icate that Aip1 is a cofilin-dependent actin depolymerization factor and not a barbed-end-capping fac

104 eracts with cofilin, an F-actin severing and depolymerization factor, and contributes to the regulati

105 aturation factor-gamma (GMFG), a novel actin depolymerization factor/cofilin superfamily protein that

106 Additionally, it acts as an enhancer of depolymerization for taxol-stabilized tubulin.

107 of GlpQ, revealed distinct mechanisms of WTA depolymerization for the two enzymes; GlpQ catalyzes exo

108 Hep III) effectively catalyzes the heparosan depolymerization, forming unsaturated disaccharides that

109 o a stochastic process of polymerization and depolymerization from their plus ends termed dynamic ins

110 dependence on Ca(2+) or low pH for the actin depolymerization function, interestingly, G1-G2 and its

111 , which undergo cycles of polymerization and depolymerization generating straight and curved microtub

112 with Latrunculin A showed actin cytoskeleton depolymerization, generating a steady SPR signal decreas

113 s involving enzymatic digestion and chemical depolymerization have been developed to determine the ty

114 le stochastically between polymerization and depolymerization, i.e. they exhibit "dynamic instability

115 opment of a photocatalytic system for lignin depolymerization in a continuous microreactor is a super

116 in washout experiments to induce microtubule depolymerization in a controlled manner at different tim

117 resent a rather counterintuitive role of BAR depolymerization in regulating the shape evolution of ve

118 on microscopy (dSTORM), we show that F-actin depolymerization in spines leads to a breakdown of the n

119 reward, is vulnerable to disruption by actin depolymerization in the basolateral amygdala complex (BL

120 Furthermore, the rate of depolymerization in the methoxybenzene-based system is t

121 merization in the cell periphery and keratin depolymerization in the more central cytoplasm were both

122 sly shown to stabilize MT minus-ends against depolymerization in vitro and in vivo.

123 on of a growth pause just before microtubule depolymerization, indicating an important role of the ma

124 K370 also inhibited MT depolymerization induced by dilution in vitro and by noc

125 less pronounced softening effects for actin depolymerization induced via latrunculin A.

126 th latrunculin A, a drug that leads to actin depolymerization, induces dispersal of the Cdc42 module

127 ors: active interfaces transduce microtubule depolymerization into mechanical work, and passive inter

128 ting duct cells, filamentous actin (F-actin) depolymerization is a critical step in vasopressin-induc

129 Depolymerization is an important starting point for many

130 t of fundamentally new approaches for lignin depolymerization is challenged by the complexity of this

131 easing their density; such local microtubule depolymerization is necessary for GSIS, likely because g

132 oes not mimic MB, demonstrating that F-actin depolymerization is not responsible for unidirectional t

133 growth persistence is reduced, inhibition of depolymerization is sufficient for pseudopod maintenance

134 ization, and pharmacologically induced actin depolymerization is sufficient to enhance Kv2.1 surface

135 The role of photocatalysis in such lignin depolymerizations is questionable as the dissolution pro

136 lymerization and 'curved' during microtubule depolymerization) is an essential requirement for accura

137 lity of the G1 domain, essential for F-actin depolymerization, is indirectly regulated by the gelsoli

138 to control cell functions by regulating the depolymerization kinetics of force-bearing actin filamen

139 This preferential binding protracted the depolymerization kinetics of Lys48-linked ubiquitin chai

140 c network architecture by showing that actin depolymerization leads to increased sheet fluctuation an

141 e microtubules grow faster and transition to depolymerization less frequently compared with brain mic

142 Drebrin inhibits depolymerization mainly at the barbed end of F-actin.

143 ive polymers, which degrade by an end-to-end depolymerization mechanism in response to the cleavage o

144 Practical, high-yield lignin depolymerization methods could greatly increase biorefin

145 cates chemical conversion efforts, and known depolymerization methods typically afford ill-defined pr

146 of C. difficile adherence regulated by actin depolymerization, microtubule restructuring, subsequent

147 Blocking actin depolymerization, Na(+)/H(+) exchange, PI3K, and Pak1 ki

148 ments at the periphery of the IS, coupled to depolymerization near the center, generates a centripeta

149 ular weight were recovered from fermentative depolymerization of a native EPS produced by Pseudomonas

150 gulated through cycles of polymerization and depolymerization of actin cytoskeletal networks.

151 along microtubules is enhanced >/= 5-fold by depolymerization of actin cytoskeleton with latrunculin

152 Nucleocapsid transport was arrested upon depolymerization of actin filaments (F-actin) and inhibi

153 Depolymerization of actin filaments is vital for the mor

154 contrast, phalloidin, an agent that prevents depolymerization of actin filaments, inhibits Nrf2 trans

155 actin-spectrin binding and cofilin-mediated depolymerization of actin filaments, play an essential r

156 ndant actin-severing protein involved in the depolymerization of actin filaments.

157 ily function is to regulate the severing and depolymerization of actin filaments.

158 Depolymerization of actin led to resumed granule secreti

159 Furthermore, depolymerization of actin preserves cell softening in th

160 Depolymerization of actin relieves the ptc1Delta cER inh

161 Upon efficient depolymerization of actin, pearls of variable size are f

162 ary actin-ADP-ribosylating toxin that causes depolymerization of actin, thereby inducing formation of

163 ed by activation of Slt2p and is reversed by depolymerization of actin.

164 s positively to facilitate the 2,4-D-induced depolymerization of actin.

165 of polysaccharide lyases, which catalyze the depolymerization of anionic polysaccharides via a beta-e

166 Polysaccharide lyases (PLs) catalyze the depolymerization of anionic polysaccharides via a beta-e

167 f antioxidants, whereas latrunculin-mediated depolymerization of appressorial F-actin is competitivel

168 symmetry; however, how the cortex causes the depolymerization of astral microtubules during asymmetri

169 lefin polymerization, alkane hydrogenolysis, depolymerization of branched polymers, ring-opening poly

170 uctural and mechanistic aspects of oxidative depolymerization of cellulose by PMOs and considers thei

171 most intricate nanomachines dedicated to the depolymerization of complex carbohydrates.

172 The depolymerization of complex glycans is an important biol

173 charide reserves provides a facile route for depolymerization of constituent polysaccharides into sim

174 apid destruction of the device due to acidic depolymerization of cPPA.

175 of Abeta fibrillar polymerization and direct depolymerization of existing Abeta fibrils.

176 focal microscopy, we found that AMPK induced depolymerization of F-actin (filamentous actin).

177 Depolymerization of F-actin abrogated exclusion.

178 The central domain inhibits the depolymerization of F-actin and is also responsible for

179 s to behavioral dysfunction, indicating that depolymerization of F-actin is causal and not consequent

180 By exploiting the fact that depolymerization of F-actin unleashes SVs focused at the

181 A role in depolymerization of highly substituted chemically comple

182 This finding is consistent with depolymerization of initially high-tension actin stress

183 Depolymerization of microfilaments and microtubules, and

184 abilized moesin and directional memory while depolymerization of microtubules (MTs) disoriented moesi

185 ntly on micropatterned strips, we found that depolymerization of microtubules caused cells to change

186 Conversely, depolymerization of microtubules drastically alters the

187 The injury induces a fast spike of calcium, depolymerization of microtubules near the injury site, a

188 Arp2/3 complex, and it was not altered upon depolymerization of microtubules or inhibition of N-WASP

189 Depolymerization of microtubules or loss of Kms1 leads t

190 nism for metazoan kinetochores to couple the depolymerization of microtubules to power the movement o

191 Depolymerization of microtubules, deletion of the KIF5 m

192 Our results show that MCAK-mediated depolymerization of MTs is specifically targeted to the

193 MICAL-2 induces redox-dependent depolymerization of nuclear actin, which decreases nucle

194 Here we describe a method for the depolymerization of oxidized lignin under mild condition

195 of poly(aryl ether sulfone)s (PSUs) from the depolymerization of PCs and in situ polycondensation wit

196 Ripening events are accompanied by gradual depolymerization of pectic polysaccharides, including ho

197 ermediate phases of papaya ripening, partial depolymerization of pectin to small size with decreased

198 Microbial depolymerization of plant cell walls contributes to glob

199 e by stimuli-induced head-to-tail continuous depolymerization of poly(benzyl ether) macro-cross-linke

200 Depolymerization of poly(tert-butyl 3,4-dihydroxybutanoa

201 lso known as lytic PMOs (LPMOs), enhance the depolymerization of recalcitrant polysaccharides by hydr

202 Depolymerization of sheaths and subsequent MS/MS analyse

203 The direct depolymerization of SiO2 to distillable alkoxysilanes ha

204 We report herein the base-catalyzed depolymerization of SiO2 with diols to form distillable

205 APTA-based calcium chelators cause immediate depolymerization of spindle microtubules in meiosis I an

206 groups caused a partial disorganization and depolymerization of starch granules.

207 filamentous actin (F-actin) and we observed depolymerization of synaptosomal F-actin accompanied by

208 identified as impacting RID(Vc) function in depolymerization of the actin cytoskeleton and inactivat

209 Furthermore, depolymerization of the actin cytoskeleton decreased con

210 he microtubule-associated protein XTP or the depolymerization of the actin network do not affect this

211 es individual domains, resulting in not only depolymerization of the crystalline form but also exposu

212 Relocation upon depolymerization of the dynamic filaments suggests the p

213 Depolymerization of the filamentous actin cytoskeleton b

214 ttachment of xyloglucan to cellulose hampers depolymerization of the latter, it is possible that the

215 at spindle poles, thereby switching off the depolymerization of the minus ends of outwardly sliding

216 We found that depolymerization of the transient polymer, cyclic poly(p

217 this outward sliding of ipMTs is balanced by depolymerization of their minus ends at the poles, produ

218 ule dynamics involves the polymerization and depolymerization of tubulin dimers and is an essential a

219 f cells in G2/M phase (mitotic blockade) and depolymerization of tubulin in MCF-7 cells.

220 blocks the reduction in phosphoactin and the depolymerization of tubulin that normally occurs in LFD,

221 rotubule ends during both polymerization and depolymerization of tubulin.

222 r weight heparins (LMWH) prepared by partial depolymerization of unfractionated heparin are used glob

223 d that these changes result from substantial depolymerization of unphosphorylated NM2 filaments to mo

224 high-value alpha,beta-unsaturated esters to depolymerization of unsaturated polymers.

225 located in genetic loci that orchestrate the depolymerization of yeast alpha-mannans, it is likely th

226 This selective effect of depolymerization on METH-associated memory was immediate

227 ffect of latrunculin-B (Lat-B)-induced actin depolymerization on outflow physiology in live mice.

228 in the dimer pool may be a consequence of MT depolymerization or breakdown.

229 nvaginations (PNEIs), similar to microtubule depolymerization or down-regulation of the dynein cofact

230 oning was impaired by inhibiting microtubule depolymerization or dynein.

231 increased flux can result in rapid filament depolymerization or maintenance of short filaments.

232 times and indicated actin polymerization and depolymerization over an extended region.

233 ment of dynein to the actin cortex, as actin depolymerization phenocopies dynein depletion, and direc

234 ity of cytoplasmic polymerization (PilB) and depolymerization (PilT) ATPases via their interactions w

235 biochemical routes combining lignin chemical depolymerization, plant metabolic engineering, and synth

236 HSP70 transgene/speckle association by actin depolymerization prevented significant heat shock-induce

237 g oligosaccharides obtained by synthetic and depolymerization procedures.

238 sis, which indicates that the polymerization-depolymerization process is reversible.

239 from an organosolv lignin through a two-step depolymerization process.

240 Exopolysaccharide-depolymerization products (EDP) varying in molecular wei

241 tion of both enzyme-derived and nitrous acid depolymerization products for structural analysis of HS

242 ization, whereas GPCR/cAMP signals and actin depolymerization promote Ski protein stability.

243 nversal FRAP experiments show that the actin depolymerization promotes the dissociation of V1-V0domai

244 UNC-60, a cofilin ortholog and actin server/depolymerization protein, further indicating that EPN-1

245 Continuous head-to-tail depolymerization provides faster rates of response than

246 Significant acceleration in cPPA depolymerization rate is triggered by the combination of

247 its in poly(carbamates) increase the overall depolymerization rate.

248 methoxybenzene-based repeating unit provides depolymerization rates that are 143x faster than oligome

249 gn of autonomous motors powered by the rapid depolymerization reaction of poly(2-ethyl cyanoacrylate)

250 The response is a signal-induced depolymerization reaction that is continuous and complet

251 Polymerization and depolymerization reactions can be controlled locally at

252 Actin depolymerization reagent latrunculin-B (Lat-B) abolished

253 Both glucose stimulation and F-actin depolymerization recruit a fraction of nearly immobile y

254 chemical initiator, effectively completing a depolymerization-repolymerization cycle.

255 aging or stress, tissues undergo repair by a depolymerization-repolymerization sequence of remodellin

256 PMS contains short actin filaments that are depolymerization resistant and sensitive to spectrin, ad

257 abnormal satellites, as complete microtubule depolymerization results in the disappearance of these a

258 ecreted enzymes that initiate lignocellulose depolymerization serve a crucial step in the bioconversi

259 placement from its actin-binding site, actin depolymerization/severing, and, ultimately, defects in s

260 s level of detail can fully optimized lignin depolymerization strategies be developed.

261 mers, solvating polymers, and polymerization/depolymerization strategies.

262 of new dimeric products in subsequent lignin depolymerization studies.

263 tand the mechanism by which INF2 accelerates depolymerization subsequent to severing.

264 migration, which was associated with F-actin depolymerization, suppression of PDGF-induced Rac1 guano

265 Following osmotic shock or actin depolymerization, Swe1p is stabilized, and previous stud

266 crotubule-end structure that promotes sudden depolymerization, termed catastrophe [1-4].

267 to accelerate both actin polymerization and depolymerization, the latter requiring filament severing

268 it accelerates both actin polymerization and depolymerization, the latter through an actin filament-s

269 lence of heparin source material and mode of depolymerization; third, equivalence in disaccharide bui

270 ber concentration as well as single-filament depolymerization time-courses.

271 substituted with ferulic acid, thus limiting depolymerization to fermentable sugars.

272 might be able to tune the mechanism of actin depolymerization to meet physiological demands and selec

273 By using the highly chemoselective depolymerization to prepare new ultra low molecular weig

274 laldehyde), undergoes mechanically initiated depolymerization to revert the material to monomers.

275 sion to larger molecular weights, controlled depolymerization to smaller molecular weights, or dynami

276 bstrate interface followed by its processive depolymerization to soluble sugars.

277 We previously demonstrated that actin depolymerization under force is governed by catch-slip b

278 creased rapidly and stimulated their gradual depolymerization (unlike their rapid degradation during

279 ubule lattice: GTP-bound, which is stable to depolymerization; unstable GDP-bound; and stable Taxol a

280 myosin (pSMM) filaments against ATP-induced depolymerization using a cross-linker and attached fluor

281 The influence of kappa-carrageenan (KC) depolymerization using ultrasound on its interaction wit

282 d ability of lysine mutants to mediate actin depolymerization via filament disassembly although not s

283 each 0.51+/-0.10 MPa, whereas signal-induced depolymerization via quinone methide intermediates reduc

284 nstrating that the loss of GIP-induced actin depolymerization was indeed limiting insulin exocytosis.

285 The reaction times for GAG depolymerization were significantly reduced from a few h

286 retina, and retina treated with microtubule depolymerization were used.

287 ed from alginate, by alginate lyase-mediated depolymerization, were structurally characterized by mas

288 increased by both sodium blockade and actin depolymerization, whereas increased actin polymerization

289 at TNFalpha induces geometry-dependent actin depolymerization, which enhances IkappaB degradation, p6

290 d that Aip1 regulates cofilin-mediated actin depolymerization, which is required for normal neutrophi

291 ubules when in excess, eventually leading to depolymerization, which is sequestered by co-overproduci

292 misaligned chromosomes, reduced microtubule depolymerization, which led to significant pro-M I/M Iar

293 AMPK induces actin depolymerization, which reduces vascular tone and the re

294 polymers to provide amplified responses via depolymerization while simultaneously enhancing the rate

295 nel closing switch operated by calsequestrin depolymerization will limit depletion, thereby preventin

296 ation of cationic poly(disulfide)s and their depolymerization with dithiothreitol causes the appearan

297 Finally, forced actin depolymerization with latrunculin B restored the exocyto

298 Chemical depolymerization with nitrous acid retains the uronic ac

299 They can also be recycled by depolymerization with specific solvents able to displace

300 We further show MT depolymerization within biofilms is regulated by the Srb