ライフサイエンスコーパス: deposition

1 e primarily driven by changes in atmospheric deposition.

2 eatment, such as gene expression and callose deposition.

3 cal distribution overlapping that of amyloid deposition.

4 notypes in a transgenic mouse model of Abeta deposition.

5 les in catchment soils prior to its ultimate deposition.

6 den was in patients with increased reticulin deposition.

7 hrombin generation and the subsequent fibrin deposition.

8 gamergate behaviors, such as dueling and egg deposition.

9 e waters, which occurs by upwelling and dust deposition.

10 e expression and increased glycosaminoglycan deposition.

11 conformational-specific selection and gentle deposition.

12 equired for either histone nuclear import or deposition.

13 of small nanoparticles while preventing coke deposition.

14 culations of sediment erosion, transport and deposition.

15 recovery amounted to 12-14 kg C per kg of N deposition.

16 to roles in either histone nuclear import or deposition.

17 his effect was observed before overt amyloid deposition.

18 and show that ATRX is involved in histone H3 deposition.

19 eta) but no histological evidence of amyloid deposition.

20 eomycin (BLEO)-induced fibrosis and collagen deposition.

21 llus well NOx emissions on regional nitrogen deposition.

22 kaline phosphates (ALP) activity and calcium deposition.

23 c mice at levels sufficient to drive Abeta42 deposition, Abeta38 and Abeta40 did not deposit or cause

24 frequency, pollinator effectiveness (pollen deposition ability) and pollinator importance (the produ

25 as deposited by low-temperature atomic layer deposition (ALD) as the transparent conductive oxide (TC

26 polydimethylsiloxane (PDMS) via atomic layer deposition (ALD) assisted sacrificial etching.

27 Notably, atomic layer deposition (ALD) in MOFs has recently emerged as a versa

28 lalumina surface species during atomic layer deposition (ALD) on a silver surface.

29 Here we introduce a new, robust atomic layer deposition (ALD) procedure for the preparation of molecu

30 luminum oxide film deposited by atomic layer deposition (ALD) with optically pumped NMR (OPNMR).

31 f Zinc Oxide (ZnO) deposited by atomic layer deposition (ALD).

32 Nitrogen deposition alone increased the soil C input (+20%), but

33 Mercury wet deposition also varies by geographic region and season.

34 electrolyte, the conditions of bismuth film deposition, an accumulation potential and time, the scan

35 ore, abdominal fat aspiration showed amyloid deposition and confirmed the diagnosis of amyloid light-

36 interstitial cells associated with collagen deposition and ectopic expression of the myofibroblastic

37 Recent research into thin-film deposition and etching techniques for mid-infrared mater

38 anthocyanidin trimer gallate modulates lipid deposition and fatty acid desaturation in Caenorhabditis

39 nsitive biomarkers to detect fibrotic tissue deposition and fiber atrophy in dystrophic strains.

40 Chemical vapor deposition and growth dynamics of highly anisotropic 2D

41 atic mTOR in Am mice increased hepatic lipid deposition and HIRI.

42 hical cooperation between DNA binding, H3-H4 deposition and histone tetramerization.

43 renal injury was accompanied by nonheme iron deposition and hypoxia-inducible factor-1alpha upregulat

44 ctivation in vitro, and vessel wall platelet deposition and initial hemostasis in vivo.

45 Changes in land use and climate, nitrogen deposition and invasive species are the most important t

46 in turn facilitates CENP-A(Cse4) nucleosome deposition and kinetochore assembly.

47 requires no nanofabrication beyond a single deposition and looks at the cell samples from below.

48 regulation in animals that undergo rapid fat deposition and mobilisation aids understanding of their

49 aluated the association between beta-amyloid deposition and neuroinflammation in AD.

50 titial fibrogenic cells to ensure proper ECM deposition and optimal muscle remodeling in response to

51 The film deposition and patterning are achieved in a single step.

52 olution e-beam lithography, thin film vacuum deposition and reactive-ion etching processes eliminatin

53 erogeneous seeds are effective in guiding Li deposition and realizing spatial control over Li nucleat

54 es (ROS)-dependent responses such as callose deposition and stomatal closure.

55 s provide evidence of interactions between N deposition and temperature sensitivity, which could infl

56 renders the aging brain vulnerable to Abeta deposition and the development of AD.

57 which is concomitant with a loss of H3K9me3 deposition and transcriptional derepression.

58 ficient mice also lacked the intrarenal CaOx deposition and tubular damage observed in wild-type mice

59 supramolecular layers are formed by solution deposition and we use atomic force microscopy to obtain

60 attributable to microglial activation, iron deposition, and blood-brain barrier breakdown.

61 protein6 mutant, which is impaired in H2A.Z deposition, and by H2A.Z profiling in stress conditions,

62 m wetlands due to demethylation, absorption, deposition, and degradation before reaching the sampling

63 structure of lead-free perovskite, thin film deposition, and device performance.

64 ation about the spatiotemporal localization, deposition, and function of their components is required

65 In a second step, gray scales, iodine deposition, and Hounsfield units were investigated by pr

66 ma and reduced neuroinflammation, fibrinogen deposition, and neurodegeneration in the brain.

67 m growth via mechanical deposition, chemical deposition, and oxygen diffusion.

68 ng genes important for carotenoid transport, deposition, and processing has been difficult, in contra

69 sponsiveness, mucus overproduction, collagen deposition, and Th2/Th17 inflammation.

70 affect hemicellulose strengthening, callose deposition, and the synthesis of structural defense prot

71 n of the PbS QD ink without requiring a post-deposition annealing treatment for solvent removal.

72 Amyloid aggregation and deposition are associated with many intractable human di

73 al trends of nitrogen (N) and phosphorus (P) deposition are important for quantifying their impact on

74 However, factors that underlie Abeta deposition are incompletely understood.

75 For arsenic speciation, the inputs for wet deposition are not well understood.

76 ons, as well as impacts on acid and nutrient deposition, are discussed.

77 the magnetopause model to compute the energy deposition as a function of quark-nugget mass and to ana

78 To evaluate the role of snow deposition as an input of PFAS to Maritime Antarctica, f

79 ation for their effects on glycosaminoglycan deposition as assessed by Alcian blue staining, and gene

80 ould have been attributed to reduced sulfate deposition as increases in pH favor more diverse cyanoba

81 Novel techniques of MIP deposition as thin films, surface development, and intro

82 elated increases in Abeta production, plaque deposition, as well as contextual fear and spatial memor

83 difies gene expression concomitantly to H3.3 deposition at a set of genes characterized both by eleva

84 counteracts repression by opposing H3K27me3 deposition at critical genomic regulatory regions.

85 inases GSO1 and GSO2 are required for sheath deposition at the embryo surface but not for production

86 r brush border loss, diminished tubular iron deposition, blocked the development of interstitial fibr

87 dies has been demonstrated to reduce amyloid deposition both in vitro and in vivo Because N-terminall

88 isheries has been diminished because of acid deposition but may improve as lakes recover from acidifi

89 main (p150N) that is dispensable for histone deposition but promotes the localization of specific loc

90 ercells, disorganized, and QLCS) enhance wet deposition by a factor of at least 1.6 relative to nonco

91 aged 60 to 87 years with and without amyloid deposition by a novel precise mass spectrometry method a

92 t channel bed aggradation (that is, sediment deposition by a river) following the 1999 Chi-Chi and 20

93 ucidates the molecular mechanism for histone deposition by CAF-1, a reaction that has remained elusiv

94 but dependent pathways: one enhances matrix deposition by fibrotic gene activation, whereas the othe

95 INTERPRETATION: Biomarkers of fibrillar tau deposition can be included with those of beta-amyloidosi

96 d breakdown, tribofilm growth via mechanical deposition, chemical deposition, and oxygen diffusion.

97 xacerbated lung fibrosis, increased collagen deposition, collagen 1 and 3 mRNA expression, TGF-beta p

98 he dimensions of MGNT reduced under the same deposition condition.

99 of the sputtered SiO2 films under different deposition conditions indicates that such high capacitan

100 lating under future rates of anthropogenic N deposition could remain in soil for long periods of time

101 ulfide (MoS2 ) synthesized by chemical vapor deposition (CVD) are studied using a local probe method

102 ly up-scaled the traditional chemical vapour deposition (CVD) production for NPs from mg level to 10

103 lution for direct observation of oil droplet deposition, deformation, and detachment during separatio

104 A mAb attenuated the injury-induced collagen deposition detected by immunohistochemistry and elevatio

105 By contrast, trends in climate and nitrogen deposition did not significantly contribute to changing

106 hropathy (n = 15), and calcium pyrophosphate deposition disease (CPPD) (n = 15), from the Hamann-Todd

107 interphase (SEI) but also to accommodate Li deposition/dissolution under the skin in a dendrite/moss

108 C4d deposition does not appear to be a necessary criterion f

109 put flows of summation operatorPCBs from wet deposition, dry deposition, tributary loading, and air t

110 tial proportion of HPV DNA detections may be depositions due to recent unprotected vaginal sex.

111 However, uncontrolled lithium deposition during lithium plating/stripping results in l

112 d application involves monitoring of foulant deposition during multimode cation exchange chromatograp

113 via cyclic voltammetry (CV) and electroless deposition (ED).

114 However, our understanding of N deposition effects on microbial communities is far from

115 rate the persistent ecosystem retention of N deposition even as it redistributes, without additional

116 ological processes that change intake or fat deposition even in the absence of actual food unpredicta

117 on regional NOx emission inventories and dry deposition fluxes to Clean Air Status and Trends (CASTNE

118 e chaperone responsible for histone (H3-H4)2 deposition following DNA synthesis.

119 not associated with late-life brain amyloid deposition (for >/=2 late-life vascular risk factors vs

120 (+20%), but the interaction of warming and N deposition greatly increased the soil C input by 49%.

121 , irreversible degradation of chemical vapor deposition-grown monolayer TMDs via oxidation under ambi

122 direct electron-microscopic observations of deposition growth of aligned ice crystals on feldspar, a

123 perature-swing stage in the sequential vapor deposition growth process allowed us to cool the existin

124 stal regions, and their importance to net Hg deposition has been questioned.

125 indicates that future rates of atmospheric N deposition have the potential to increase soil C storage

126 Here we present a 320 year Hg deposition history for Central Asia, based on a continuo

127 endocannabinoid, in the modulation of CSPGs deposition in a progressive model of multiple sclerosis,

128 the well-established role of apoE4 in Abeta deposition in AD.

129 ceae and S24-7) and reduction in brain Abeta deposition in aged APPSWE/PS1DeltaE9 mice.

130 eficiency led to a marked reduction in lipid deposition in aortas and isolated macrophages.

131 iB uptake suggest an atypical pattern of tau deposition in DLB.

132 We also found that the reduction of sulphur deposition in Europe and the USA lead to higher recovery

133 0 were significantly associated with amyloid deposition in HC, suggesting that these two biomarkers m

134 at the centromere is required for new CENP-A deposition in human cells.

135 ith the intrinsic non-dendritic nature of Mg deposition in Mg ion batteries.

136 We report that wall ingrowth deposition in phloem parenchyma (PP) transfer cells (TCs

137 the GPA and a parallel reduction in callose deposition in the adf3 mutant.

138 t changes in the profile of regional PrP(Sc) deposition in the brains of animals that were treated, b

139 ing in calcium oxalate crystal formation and deposition in the kidney and many other tissues, with sy

140 quids as a marker for tracking e-cig aerosol deposition in the laboratory.

141 ncidence, thrombus size, fibrin and platelet deposition in the ligated inferior vena cava, and dimini

142 iser that achieves significantly higher drug deposition in the lung compared with the existing formul

143 in mice and in reducing extracellular matrix deposition in the lung while also reducing LPA 18:2 cont

144 istological analysis showed reduced collagen deposition in the noninfarcted region in mice given SA C

145 ic influences of climate change and nitrogen deposition in these systems is critical to improve predi

146 ble lowering (WTL) and enhanced nitrogen (N) deposition in Tibetan alpine wetlands.

147 immune disease characterized by autoantibody deposition in tissues such as kidney, skin and lungs.

148 binding is not essential for H3-H4 tetrasome deposition in vitro, it is required for efficient DNA sy

149 activity (smooth muscle cell loss and fibrin deposition) in the FP-PES compared with PES and bare met

150 11A1(+) fibroblasts suggests roles in matrix deposition, inflammatory cell retention, and connective

151 ial dysfunction with increased ectopic lipid deposition, insulin resistance, and type 2 diabetes.

152 It is not known whether vascular amylin deposition is a consequence or a trigger of vascular inj

153 ng of properdin and binding secondary to C3b deposition is a critical factor contributing to this con

154 This deposition is accompanied by neuronal loss, spongiform c

155 Amyloid deposition is associated with premature loss of normal A

156 nce (NMR) spectroscopy, we show that mineral deposition is biologically driven.

157 factors directly contribute to brain amyloid deposition is less well understood.

158 These findings suggest that organ tissue deposition is reduced but not eliminated following admin

159 tructure via direct growth by chemical vapor deposition is reported.

160 Here we present a comprehensive Hg-deposition mass-balance study, and show that most of the

161 pplication of the TiOx film independently on deposition method enables not only for tuning of the spe

162 It has been found that deposition method has a significant influence on optical

163 The arrays were prepared by glancing angle deposition method.

164 which was optimized for each printer: fused deposition molding (FDM), Polyjet, and digital light pro

165 igurations using a conventional RepRap fused deposition moulding (FDM) 3D printer, which requires no

166 ique angle deposition (OAD) and under normal deposition (ND) onto the same patterned surfaces.

167 set was compiled by the Delaware Atmospheric Deposition Network (DADN) from samples taken in Camden,

168 itation in samples prepared by oblique angle deposition (OAD) and under normal deposition (ND) onto t

169 Deeper nanoparticle deposition occurred in areas of plaque neovascularizatio

170 nting, specifically oxidative chemical vapor deposition (oCVD), is demonstrated.

171 tection (LOD) for TATP are equivalent to the deposition of 15 ng TATP and are comparable with other a

172 logical tool for the control of liquid phase deposition of 2D materials.

173 Deposition of 4,4"-diiodo-m-terphenyl molecules onto eit

174 It is characterised by aberrant deposition of a 5.4 kDa protein called medin within the

175 necrotic bone, which in turn stimulated the deposition of a new bone matrix by osteoblasts.

176 Cell division in plant cells requires the deposition of a new cell wall between the two daughter c

177 r for position- and concentration-controlled deposition of a single, colorless, water-based ink conta

178 cm(2)) fuel cells based on ultrasonic spray deposition of a standard Pt/carbon electrocatalyst direc

179 uclear architecture were associated with the deposition of activating epigenetic marks across the loo

180 Deposition of aggregates of hyperphosphorylated tau prot

181 This work studies the deposition of aluminium-incorporated nickel coatings by

182 Alzheimer's disease (AD) is characterized by deposition of amyloid beta (Abeta) peptides into senile

183 In patients with Alzheimer's disease, deposition of amyloid-beta is accompanied by activation

184 The formation and deposition of amyloids is associated with many diseases.

185 ound organic matter, which signals increased deposition of anthropogenic atmospheric N on the open oc

186 by a facile sonochemical method via in situ deposition of antibacterial prickly Zn-CuO nanoparticles

187 and cartilage in vertebrates, involving the deposition of calcium- and phosphate-containing hydroxya

188 ortex influence cell shape by patterning the deposition of cell wall materials.

189 The deposition of cellulose is a defining aspect of plant gr

190 rane domains), and its essentiality in polar deposition of chitin.

191 ed cellular apoptosis (caspase-3/7) and lung deposition of collagen and C' (C5b-9).

192 denocarcinoma (PDAC) is partly attributed to deposition of collagen and hyaluronan, leading to inters

193 gnaling induces expression of col12a1a/b and deposition of Collagen XII, which is necessary for axons

194 Here, we report physical vapor deposition of Cu thin films on large-format ( approximat

195 his coloration is often produced through the deposition of diet-derived carotenoid pigments, yet the

196 ed alkaline phosphatase activity and calcium deposition of encapsulated hASCs.

197 Deposition of epitaxial germanium (Ge) thin films on sil

198 -VEGF treatment is directly linked to strong deposition of fibrillar extracellular matrix (ECM) compo

199 Conclusion Tissue deposition of gadolinium was two- to fourfold higher fol

200 il to release from CAF1, indicating that DNA deposition of H3-H4 tetramers by CAF1 requires a hierarc

201 ith DNA molecules of this size, resulting in deposition of H3-H4 tetramers.

202 se complex, were both successful in targeted deposition of H3K27me3.

203 tion, with only minor contributions from the deposition of Hg(ii) via precipitation or AMDEs.

204 issive euchromatic environments, and promote deposition of histone H3 Lys9 trimethylation (H3K9me3) f

205 complexes and of PRC2, the latter leading to deposition of histone H3 lysine 27 methylation chromosom

206 pe mice was associated with a time-dependent deposition of hyaluronic acid (HA) and increased express

207 emble into a 3D organic matrix directing the deposition of hydroxyapatite.

208 Serum DSA levels and the deposition of IgG and C4d in the allograft were equivale

209 ol phase, and (iii) dried spot obtained from deposition of liquid suspensions.

210 cts of trees on urban runoff, which includes deposition of nutrient-rich leaf litter onto streets con

211 At regional scale, HFOC stably dominates the deposition of OC (95.4%), whereas DOC and LFOC in ZR is

212 Jarid2-deficient pancreases exhibit impaired deposition of RNAPII-Ser5P, the initiating form of RNAPI

213 C1s by promoting chromatin accessibility and deposition of STAT5 at the promoter of Id2 in response t

214 p neurodegenerative disease characterized by deposition of tau tangles in the brain are highly suscep

215 ether, our results illuminate how tumor cell deposition of tenascin-C in the tumor microenvironment p

216 ed with Set1) complex, which is required for deposition of the histone 3 Lys4 trimethyl (H3K4me3)-act

217 f current oscillations during potentiostatic deposition of the imprinted poly(2,3'-bithiophene) film.

218 nd graphene oxide with NaBH4 and the in situ deposition of the metal nanoparticles on the 2D carbon n

219 ed by water-column stratification during the deposition of the organic-rich (sapropel) interval known

220 vaporation of the solvent and the subsequent deposition of the PbS QD ink without requiring a post-de

221 g sediments can only be explained by initial deposition of this facies in a freshwater setting.

222 Excessive deposition of type I collagen causes fibrotic diseases.

223 mma-driven E3 ubiquitin ligase mediating the deposition of ubiquitin around pathogen inclusions.

224 g durations of juvenile phase, and extensive deposition of wall ingrowths was observed in rejuvenated

225 the fiber with silver layer followed by the deposition of XO entrapped Ta2O5 nanostructures.

226 and the postmortem presence of Lewy bodies, depositions of insoluble alpha-synuclein, and other prot

227 n diabetic nephropathy tissue and glomerular depositions of protein S.

228 f colloidal capsules, the colloidal particle deposition on (sacrificial) templates, the amphiphilicit

229 lization of nanocavities obtained by surface deposition on a blank photonic crystal.

230 onserved in TENG-ESI, and that patterned ion deposition on conductive and insulating surfaces is poss

231 e platelets prevented oxLDL-induced platelet deposition on immobilized collagen in response to arteri

232 e use of ED-XRF spectrometry after thin film deposition on special sample retainers and a subsequent

233 e molecular processes important for papillae deposition on the cell wall surface, we identified the G

234 endent manner: (i) directly, through TiO2 NP deposition on the cell wall, delaying the collapse of th

235 CO2 concentration, and SO4 and nitrogen deposition on two broadleaf tree species in a temperate

236 antibody to a target antigen to guide biotin deposition onto adjacent proteins in fixed cells and pri

237 using conformal oblique incidence thin film deposition onto an optical grating substrate, it is poss

238 on-specific interactions, facilitating their deposition onto DNA, and aiding in their eviction from D

239 in TgF344-AD rats, without altering amyloid deposition or indicators of neuroinflammation.

240 No detectable neural tissue deposition or MR imaging signal was observed in control

241 (SN)-BER of a damaged base requires histone deposition or nucleosome remodeling is unknown, unlike n

242 which leads to premature cell death, callose deposition, or phloem protein accumulation, causing a lo

243 by other means, such as degradation, matrix deposition, or stiffening.

244 of different inks and determination of their deposition order are important forensic tasks when evalu

245 correct conclusions to be made regarding ink deposition order.

246 By carefully selecting the material deposition parameters, we show that both of the device l

247 A and ATRX function in complementary histone deposition pathways.

248 P deposition peaked around 2010 in South Asian forests and

249 baseline to 1 and 2 y, and percentage Abeta deposition per year, were assessed across Abeta+ and Abe

250 Issues regarding incorrect apparent order of deposition persisted through the variation of all these

251 Drop drying and deposition phenomena reveal a rich interplay of fundamen

252 th and suggest that, so far unknown, sulphur deposition plays a significant role in the carbon balanc

253 hanging the substrate temperature during the deposition process to promote the growth of inclined ZnO

254 ed gold nanoparticles using a layer-by-layer deposition process.

255 Deposition processes were found to impact the aerosol yi

256 ch as cell wall biosynthesis, polysaccharide deposition, protein-carbohydrate interactions, and cell-

257 nd, and substantially increases their energy deposition rate in matter.

258 A versatile Rotary Chemical Vapour Deposition (RCVD) technique for the in-situ synthesis of

259 because of decreased CH4 emissions, while N deposition reduced GWP from 21.0 to -163.8 g CO2 -eq m(-

260 oPOM at a greater rate under experimental N deposition, relative to the ambient treatment.

261 tributions to Earth surface oxidation and Fe deposition remain unknown.

262 s that, by 2010, anthropogenic atmospheric N deposition represented 20 +/- 5% of the annual N input t

263 In pleural fibrosis excess collagen deposition results in pleural thickening, increased stif

264 These trends suggest that snow deposition, scavenging sea-salt aerosol bound PFAS, play

265 carotenoids with fundamental changes of the deposition state of carotenoids in goji berries.

266 efficient Lewis acid-base adduct in the SnI2 deposition step to modulate its volume expansion and fas

267 anoscale films can be tuned by the number of deposition steps.

268 t of PFAS to Maritime Antarctica, fresh snow deposition, surface snow, streams from melted snow, coas

269 g of infected bone revealed increased fibrin deposition surrounding bacterial abscesses in obese/T2D

270 (GNSs) using a supercritical-fluid-assisted deposition technique to increase the electrochemical sen

271 urrently, the most widely used metal contact deposition techniques are limited to widths and aspect-r

272 Both deposition techniques increased electrode capacitance, b

273 The sequence of the technological steps, the deposition temperatures of the thin films and the parame

274 the eastern United States recover from acid deposition, the stress to the most susceptible populatio

275 ds are thought to contribute to Abeta plaque deposition, these 1,5-diarylimidazoles provide tools to

276 abnormal double-peak (annular shaped) energy deposition through dual-wavelength synthesis of the fund

277 creased from 98 to 126nm upon increasing the deposition time from 225 to 675s.

278 By anchoring peat-derived GEM dry deposition to modern atmospheric GEM levels we are able

279 unctions as a platform for targeting histone deposition to replication fork, through which RPA couple

280 were also increased, further linking fibrin deposition to S. aureus expression of clfA and infection

281 mation operatorPCBs from wet deposition, dry deposition, tributary loading, and air to water exchange

282 onomous JAK2 signaling regulates liver lipid deposition under conditions of excess dietary fat.

283 acer, and (210)Po is determined through self-deposition using (209)Po as a yield tracer.

284 effect of precipitation type on mercury wet deposition using a new database of individual rain event

285 record shows that variations in glacial dust deposition variability on centennial-millennial timescal

286 However, the extent of gadolinium deposition varies between agents.

287 mercury depletion events', or AMDEs) and wet deposition via precipitation are sources of Hg to the Ar

288 sts and MC3T3-E1 cells only fibulin-4 matrix deposition was lost while other fibulin family members o

289 hest for ultrafine particles, estimated lung deposition was mainly from accumulation and coarse parti

290 Motor cortical fibrin(ogen) deposition was significantly over-represented in MS comp

291 , and corresponding changes in wall ingrowth deposition were observed when miR156 was overexpressed o

292 epared by soft-landing electrospray ion beam deposition, which allows chemical- and conformational-sp

293 e differentiation precede MyoA synthesis and deposition, which occurred only in the developing protub

294 Intervention into amyloid deposition with anti-amyloid agents like the polyphenol

295 bled selective and quantitative nanoparticle deposition with blue emission.

296 is derived from gaseous elemental Hg (Hg(0)) deposition, with only minor contributions from the depos

297 ggest that the maize zygote starts cell wall deposition within 30 seconds after fusion with a sperm [

298 a bedrock basin in Pine Island Bay indicates deposition within a low-energy lake environment.

299 possible heterogeneity of pesticide location/deposition within the hive to compare with exposure leve

300 We find that DNMT3A occupancy and mCA deposition within the transcribed regions of genes is ne