ライフサイエンスコーパス: depressive episode

1 t (eg, medical burden, age at onset of first depressive episode).

2 arker for a negative affective bias during a depressive episode.

3 was defined in terms of duration of current depressive episode.

4 nostic Interview criteria for 12-month major depressive episode.

5 apse and recurrence of bipolar type II major depressive episode.

6 resistance, age, and duration of the current depressive episode.

7 emoval of the bereavement exclusion in major depressive episode.

8 to the United States and the odds of a major depressive episode.

9 history but who were not in a current major depressive episode.

10 y experienced the onset of their first major depressive episode.

11 ry to enhance vocational functioning after a depressive episode.

12 polar disorder over the 9 months following a depressive episode.

13 ents who were being treated for DSM-IV major depressive episode.

14 a 2-year follow-up of patients with a major depressive episode.

15 olar I disorder experiencing a current major depressive episode.

16 e individuals, grief can evolve into a major depressive episode.

17 sed at presentation for treatment of a major depressive episode.

18 r subjects successfully treated for an acute depressive episode.

19 oms than those who had not developed a major depressive episode.

20 correlated positively with length of current depressive episode.

21 than 20% of females met criteria for a major depressive episode.

22 y be at greater risk of cycling into a major depressive episode.

23 ptoms and impairment after resolution of the depressive episode.

24 89 patients met criteria for a current major depressive episode.

25 during the first 10-15 years after an index depressive episode.

26 iteria for generalized anxiety disorder in a depressive episode.

27 in the ACC during a moderate to severe major depressive episode.

28 roups all diagnosed with Major Depression or Depressive Episode.

29 r patients with a medication-resistant major depressive episode.

30 sed state and is a potential biomarker for a depressive episode.

31 pectrum disorder, the illness started with a depressive episode.

32 anced than simply one of recurring manic and depressive episodes.

33 r adults to an increased risk for relapse of depressive episodes.

34 Recurrence was defined in terms of number of depressive episodes.

35 mptoms, depression diagnosis, and cumulative depressive episodes.

36 vidence of bipolarity in patients with major depressive episodes.

37 sociated with higher frequency of subsequent depressive episodes.

38 a group at very high risk for onset of major depressive episodes.

39 for DSM-IV (SCID) determined incident major depressive episodes.

40 were seen in time to recurrence of manic and depressive episodes.

41 t least 1 syndromal recurrence, particularly depressive episodes.

42 ants who had experienced a greater number of depressive episodes.

43 mood disorders has focused largely on major depressive episodes.

44 ning 49% of the variance in the liability to depressive episodes.

45 came depressed during the study had no prior depressive episodes.

46 manic episodes, although it is equivocal for depressive episodes.

47 e, and patient characteristics seen in 9,054 depressive episodes.

48 ssness or excessive guilt during their major depressive episodes.

49 a core role were strongly linked to risk for depressive episodes.

50 ssant drugs can promote remission from acute depressive episodes.

51 manic, 0.72 for hypomanic, and 1.0 for major depressive episodes.

52 holds promise for preventing progression to depressive episodes.

53 he "with mixed features" specifier for major depressive episodes.

54 had at least 1 parent with current or prior depressive episodes.

55 ood and hormone secretion) is altered during depressive episodes.

56 sive episodes and high-risk states for major depressive episodes.

57 of antidepressant drugs in the management of depressive episodes.

58 structures of mixed states based on manic or depressive episodes.

59 reversals one or more of which precipitated depressive episodes.

60 me information for 100 patients with a major depressive episode, 100 with obsessive-compulsive disord

61 Fifty unmedicated patients in a major depressive episode (21 with no history of suicide attemp

62 ces, with more than twice as many developing depressive episodes (298, 34.7%) as those who developed

63 compared with 4% of the patients with major depressive episode, 3% of those with OCD, and 0% of thos

64 pisodes (9.2% compared with 0.8%), and major depressive episodes (32.0% compared with 14.9%).

65 s was as follows: lifetime and current major depressive episode, 35.4% and 14.7%, respectively; suici

66 Co-occurring neuroses were depressive episode (37%), generalized anxiety disorder (

67 ad unipolar depression (with a current major depressive episode, a 17-item Hamilton Depression Rating

68 omen aged 30 to 53 years with a DSM-IV major depressive episode, a 17-item Hamilton Rating Scale for

69 rsus without an antidepressant for a bipolar depressive episode accompanied by > or = 2 concurrent ma

70 er applicable to manic, hypomanic, and major depressive episodes; addition of severity dimensions for

71 ificantly increased the odds of Wave 2 major depressive episodes (adjusted odds ratio (AOR): 1.7; 95%

72 er vulnerability to postpartum triggering of depressive episodes aggregates in families and assess ho

73 thors postulated that among men with a major depressive episode, aggression, hostility, and history o

74 ust, even after adjustment for a prior major depressive episode, alcohol abuse or dependence, and dru

75 volves assessment of the presence of a prior depressive episode along with sleep disturbance.

76 eases the risk of suicidal behavior; a major depressive episode also increases the risk for suicidal

77 The prevalence of major depressive episodes among Alzheimer's disease patients i

78 ed in 44 unmedicated patients during a major depressive episode and 35 healthy controls.

79 -IV major depressive disorder during a major depressive episode and 42 healthy volunteers were clinic

80 Twenty-four MDD subjects in a current major depressive episode and 51 previously studied healthy con

81 cation-free (ie, untreated) outpatients in a depressive episode and assessed them for cognitive funct

82 f first onset of depressive disorders (major depressive episode and dysthymia) and anxiety disorders

83 in major depressive disorder (MDD) during a depressive episode and following treatment with ketamine

84 ns in 3 categories: (1) mental health (major depressive episode and generalized anxiety disorder), (2

85 , 10th Revision (ICD-10) at age 45 years for depressive episode and generalized anxiety disorder.

86 older, who met DSM-III-R criteria for major depressive episode and had a minimum Hamilton Depression

87 1 adults who met DSM-IV criteria for a major depressive episode and had Hamilton Depression Rating Sc

88 -IV major depressive disorder during a major depressive episode and in 43 healthy volunteer compariso

89 d with depression may precede the onset of a depressive episode and influence the development and cou

90 al practice because onset is most commonly a depressive episode and looks similar to unipolar depress

91 Patients with comorbid major depressive episode and PTSD were more likely to have att

92 sion who were currently experiencing a major depressive episode and respondents whose last episode ha

93 ntreated depressed state seen during a major depressive episode and the pattern of change seen in dep

94 h Diagnostic Criteria from their index major depressive episode and/or mania were divided into residu

95 ymptom profiles compared with other types of depressive episodes and are not associated with increase

96 grouped on the basis of the number of prior depressive episodes and current depressive diagnosis.

97 Major depressive episodes and disruptive behavior disorders ar

98 oaching experienced a low incidence of major depressive episodes and exhibited a 40%-50% decrease in

99 , but patients in FFT-A spent fewer weeks in depressive episodes and had a more favorable trajectory

100 pausal age that is also present during major depressive episodes and high-risk states for major depre

101 cy in acute manic episodes, lithium in acute depressive episodes and in prophylaxis of mania and depr

102 t patients with three or more previous major depressive episodes and on a therapeutic dose of mainten

103 Data on symptoms of major depressive episodes and sleep problems were examined for

104 ive view of life and the self, more lifetime depressive episodes and suicide attempts, and greater sy

105 r clinical management are the following: (1) depressive episodes and symptoms, which dominate the cou

106 disorder (psychosis, manic episode, or major depressive episode) and a substance use disorder.

107 ssive symptoms that do not meet criteria for depressive episodes); and bipolar disorder not otherwise

108 alizing (anxiety and eating disorders, major depressive episode, and cluster C, borderline, and paran

109 Posttraumatic stress disorder, major depressive episode, and use of antidepressant and benzod

110 r age at onset, a greater previous number of depressive episodes, and eight individual symptom items

111 ion between genetic risk, number of previous depressive episodes, and life event exposure in the pred

112 ashion with a greater proportion of weeks in depressive episodes, and this relationship persisted ove

113 to assess the primary outcome, new onsets of depressive episodes, and to calculate depression-free da

114 n of severity dimensions for manic and major depressive episodes; and removal of the bereavement excl

115 However, other symptoms of major depressive episodes-anhedonia, feelings of worthlessness

116 in the cholinergic system observed during a depressive episode appears to resolve during euthymia.

117 th likely diagnoses of both PTSD and a major depressive episode are at a 4-fold increased risk of pre

118 nality disorder diagnoses established during depressive episodes are a valid reflection of personalit

119 Little is known about how often bipolar depressive episodes are accompanied by subsyndromal mani

120 mania and hypomania define bipolar disorder, depressive episodes are more common and impairing, with

121 patients who, despite full remission from a depressive episode, are at substantial risk of relapse w

122 le and female subjects in both cohorts had a depressive episode as the first episode of bipolar illne

123 safety of standard antidepressant agents for depressive episodes associated with bipolar disorder (bi

124 done in the treatment of patients with major depressive episodes associated with bipolar I disorder.

125 amined suicide attempts included severity of depressive episode at study intake and family history of

126 d anxiety disorder at T2 and T3 and of major depressive episode at T2.

127 patients diagnosed with Major Depression or Depressive Episode (average age = 49 +/- 12.9), the seco

128 women who received IPT recovered from their depressive episode based on HRSD scores of 6 or lower (3

129 (MDD) indicate that the onset of subsequent depressive episodes becomes increasingly decoupled from

130 ssess respondents' lifetime history of major depressive episode between the ages of 18 and 39.

131 Participants could not be in a current depressive episode but had to have subsyndromal depressi

132 Manic symptoms often accompany bipolar depressive episodes but may easily be overlooked when th

133 as associated with a greater number of prior depressive episodes but not current depressive diagnosis

134 ry who are at high risk for developing major depressive episode by 3 months' postinjury, which could

135 baseline decreased the risk of having a new depressive episode by 6% (adjusted relative risk = 0.94,

136 unknown how the likelihood of falling into a depressive episode can be assessed.

137 condition had significantly fewer onsets of depressive episodes compared with those in UC.

138 Relapse of major depressive episode, compared among the 3 continuation gr

139 lative episodes on later CRP, but cumulative depressive episodes continued to predict CRP levels inde

140 agnoses, 2 or more comorbid diagnoses, major depressive episode (current and lifetime), past 30-day s

141 subsyndromal depressive symptoms or a prior depressive episode currently in remission.

142 were diagnosed as having unipolar or bipolar depressive episodes defined as moderate or severe by DSM

143 er at least 8 weeks of full remission from a depressive episode (defined as a value of 1 on the weekl

144 ts, who are at an elevated lifetime risk for depressive episodes, demonstrate distinctive patterns of

145 t baseline, 6 weeks, 1 year, and 2 years for depressive episodes, depressive symptoms, sleep quality,

146 ween childhood maltreatment and a subsequent depressive episode diagnosis was moderated by 5-HTTLPR g

147 18 years old who recovered from their major depressive episode during initial open-label fluoxetine

148 Survival analysis of incident major depressive episodes during a median 15-month follow-up f

149 ects (16.9%) with prior depression developed depressive episodes during follow-up, compared to only o

150 lifetime mental health service use, and new depressive episodes during the 3-year follow-up period.

151 nt effect was driven by a lower incidence of depressive episodes during the first 9 months after enro

152 The risk of new depressive episodes during the follow-up period among pa

153 lowing disorders: affective disorders (major depressive episode, dysthymia, manic episode), anxiety (

154 1.26, 1.09-1.47, p=0.003), greater number of depressive episodes (eight studies, 4025 participants; 1

155 The DSM-IV criteria for major depressive episodes exclude brief episodes that are bett

156 The occurrence of multiple depressive episodes exerted the greatest effect on later

157 r cytokines, have been associated with major depressive episodes following the experience of stressfu

158 posttraumatic stress disorder (PTSD), major depressive episode, generalized anxiety disorder, and su

159 imer's disease patients with a current major depressive episode had earlier mean ages at onset, a hig

160 disorder or a history of at least one major depressive episode had lower levels of myo-Inositol comp

161 ent-resistant major depression whose current depressive episode had not responded adequately to treat

162 jects who fulfilled the criteria for a major depressive episode had psychotic features.

163 Patients during depressive episodes had significantly smaller hippocampa

164 ts with major depressive disorder in a major depressive episode have fewer serotonin transporter site

165 her personality disorders diagnosed during a depressive episode have long-term outcomes more typical

166 Subjects in a major depressive episode have lower serotonin transporter bind

167 Unipolar and bipolar depressive episodes have a similar clinical presentation

168 Bereavement-related, single, brief depressive episodes have distinct demographic and sympto

169 ypomanic episodes (hazard ratio=2.29), major depressive episodes (hazard ratio=1.99), and disruptive

170 ime features were associated with more prior depressive episodes, higher levels of depressive symptom

171 d an additional diagnosis of a current major depressive episode, however PD was the primary diagnosis

172 The effect of cumulative depressive episodes, however, continued to be significan

173 hazard ratio (HR) of a probable or definite depressive episode (ie, depressive symptom rating score

174 There was a four-fold greater proportion of depressive episode in the SELCoH sample than the APMS sa

175 by stressors such as life events or a major depressive episode in the setting of a propensity for ac

176 Rates of past-year major depressive episode in the total samples and among subjec

177 nal, and psychosocial predictors of incident depressive episodes in a well-characterized cohort of ol

178 d, controlled trial was conducted to prevent depressive episodes in at-risk offspring (aged 13-18 yea

179 compared with UC in preventing the onset of depressive episodes in at-risk youth over a nearly 3-yea

180 most propitious time to prevent or attenuate depressive episodes in bereaved youth may be shortly aft

181 wed up to age 18, data on the evaluation for depressive episodes in early adulthood, on childhood mal

182 howed a moderate association between PDE and depressive episodes in male (OR, 1.58) and female twins

183 oms and impairment after resolution of major depressive episodes in the community.

184 IV bereavement exclusion criterion for major depressive episodes in the DSM-5.

185 o construct a developmental model to predict depressive episodes in the year before the most recent i

186 orbid substance abuse on recovery from major depressive episodes in these patients has not been adequ

187 to reliably diagnose and characterize major depressive episodes in this population.

188 sorder was due to more severe and persistent depressive episodes in those with bipolar disorder than

189 he triggering of narrowly defined postpartum depressive episodes in women with recurrent major depres

190 rom recurrent unipolar depression (recurrent depressive episodes) in depressed patients.

191 fied based on DSM-III-R criteria for a major depressive episode, in addition to atypical features of

192 least 2 years' duration or had three or more depressive episodes (including the current episode), and

193 anesthetic medication for treatment of major depressive episodes, including those associated with bip

194 r major depression as the number of previous depressive episodes increased was strongest in those at

195 pression decreases as the number of previous depressive episodes increases.

196 A prior depressive episode is thought to increase the risk of de

197 the familial transmission of manic and major depressive episodes is independent despite the high magn

198 nformation regarding the presence of a major depressive episode, its duration, and its severity was d

199 s predicted both endpoints, whereas previous depressive episodes, male sex, and suicidality additiona

200 disorder in patients who experience a major depressive episode may lead to inappropriate treatment a

201 of borderline personality disorder and major depressive episode may obscure characteristics of suicid

202 Recurrent major depressive episodes may be a risk factor for subclinical

203 n 67 patients currently experiencing a major depressive episode (MDD, n = 45; BD, n = 22).

204 BPD subjects (n = 14), subjects with a major depressive episode (MDE) only (n = 14), and healthy cont

205 hors examined whether early onset of a major depressive episode (MDE) predicted a subsequent decrease

206 ckness behaviors that present during a major depressive episode (MDE), such as low mood, anhedonia, a

207 pairing depressed mood, anhedonia, and major depressive episode (MDE).

208 rges, stressors such as life events or major depressive episodes (MDEs) determine the timing of suici

209 esponse occurs in approximately 40% of major depressive episodes (MDEs), and one approach to solve th

210 t central to the diagnosis of unipolar major depressive episodes (MDEs), these symptoms have been fou

211 orders, including psychotic, manic and major depressive episodes (MDEs).

212 Patients with MDD in a current major depressive episode (N=104) with an inadequate response t

213 Inpatients with a diagnosis of major depressive episode (N=156) were assessed for PTSD, suici

214 polar disorder seeking treatment for a major depressive episode (N=314) were followed for 2 years.

215 The "kindled" state, wherein depressive episodes occur with little provocation, may b

216 The authors prospectively studied major depressive episodes occurring within 2 years to determin

217 tatus is associated with increased risk of a depressive episode (odds ratio = 3.0, 95% confidence int

218 risk of developing recurrent and persistent depressive episodes (odds ratio=2.27, 95% confidence int

219 tween 14 medication-free patients in a major depressive episode of at least moderate severity and 13

220 patients presenting for treatment of a major depressive episode of at least moderate severity underwe

221 Maternal depression, a non-psychotic depressive episode of mild to major severity, is one of

222 s in the clinical presentations of the major depressive episodes of Alzheimer's disease patients and

223 Although the major depressive episodes of Alzheimer's disease patients and

224 shifting hypothesis, which suggests that the depressive episodes of SAD are caused by misalignments b

225 , 2,154 subjects developed a new-onset major depressive episode; of these, 457 subjects switched to a

226 xamine the effect of comorbid PTSD and major depressive episode on suicidal behavior.

227 fined as recurrent hypomania without a major depressive episode or with fewer symptoms than required

228 to be moderately stable only in consecutive depressive episodes or if episode severity is considered

229 sion (OR = 1.92; 95%CI = 1.64-2.26), a brief depressive episode (OR = 2.14; 95%CI = 1.88-2.43) or dep

230 ve episode (OR = 2.14; 95%CI = 1.88-2.43) or depressive episode (OR = 2.43; 95%CI = 2.21-2.67).

231 utility (e.g., mixed features specifier for depressive episodes), or problematic implementation (e.g

232 gic model for major depression that predicts depressive episodes over 1 year from 18 risk factors con

233 erior to placebo at prolonging the time to a depressive episode (P =.02).

234 every point across the life course for major depressive episode, panic disorder, and posttraumatic st

235 After their first lifetime major depressive episode, patients were divided into asymptoma

236 ay be reached by two pathways: many previous depressive episodes, perhaps driven by multiple adversit

237 f past-year mood/anxiety disorder (ie, major depressive episode, phobias, panic, generalized anxiety

238 and who were currently experiencing a major depressive episode received a single ketamine infusion (

239 cacy in prevention of both manic episode and depressive episode relapse or recurrence and the better

240 rder did not predict time to recovery from a depressive episode relative to no substance use comorbid

241 The timing of depressive episodes relative to substance dependence ser

242 n with a lifetime history of recurrent major depressive episodes relative to women with no history of

243 -controlled trials in acute, unipolar, major depressive episodes reported over the past three decades

244 Of 30 participants with major depressive episode selected for inclusion, 26 participan

245 Alcohol-use disorders are associated with depressive episodes, severe anxiety, insomnia, suicide,

246 nantly depressive, and across both manic and depressive episodes, showing essentially parallel struct

247 Conversely, Wave 1 major depressive episodes significantly increased risk of Wave

248 se spent nearly three times as many weeks in depressive episodes than did those whose intake episode

249 Symptom severity was greater for depressive episodes than manic episodes, with approximat

250 A depressive episode that is bereavement-related and has c

251 All patients were in a current major depressive episode that was nonresponsive to a combinati

252 The high rate of major depressive episodes that occur after the onset of cognit

253 During a depressive episode, the subjective perception of stressf

254 gy for the assessment and diagnosis of major depressive episodes, the prevalence of major depression

255 ith the probability of recovery from a major depressive episode, there was a significantly greater pr

256 (for example, gray matter thinning during a depressive episode), they may be less optimal for the de

257 In the absence of previous depressive episodes, those at high genetic risk frequent

258 the United States for the treatment of major depressive episodes to compare 477 subjects with a diagn

259 ificantly correlated with lifetime number of depressive episodes, trauma score, and anxiety score.

260 ere 395 elderly persons with a current major depressive episode, treated as inpatients or outpatients

261 d 795 patients who were experiencing a major depressive episode (unipolar or bipolar depression) of a

262 ge, 43.2 years) with major depression, acute depressive episode, unipolar subtype.

263 jor depressive disorder (MDD) during a major depressive episode using positron emission tomography (P

264 jor depressive disorder (MDD) during a major depressive episode using positron emission tomography im

265 The nature of chronic depressive episodes varies over time within individuals,

266 e until 25% of the individuals experienced a depressive episode was 21.4 weeks and until 25% experien

267 Secondarily, the presence of a major depressive episode was assessed using the Structured Cli

268 tpatients, the total time each had been in a depressive episode was divided into days during which th

269 rence of mania, hypomania, mixed state, or a depressive episode was examined with Cox regression.

270 Lifetime history of a single major depressive episode was not associated with plaque.

271 among patients with comorbid PTSD and major depressive episode was not due to differences in substan

272 entage of adults with new (versus recurrent) depressive episodes was 88.6% in the preadvisory period

273 The incidence of major depressive episodes was identified by the Inventory to D

274 ionship between personality, environment and depressive episodes was not always clear.

275 Longer durations during which depressive episodes went untreated with antidepressant m

276 istant major depression experiencing a major depressive episode were randomly assigned under double-b

277 pressed patients with psychosis at the index depressive episode were significantly more likely than n

278 Prospectively observed depressive episodes were identified for this analysis.

279 ssion follow-up, the rate and HR of incident depressive episodes were lower for those in the CB preve

280 hose with bereavement-related, single, brief depressive episodes were more likely to experience later

281 Risks of new manic and depressive episodes were similar but were predicted by c

282 s or older, and required new treatment for a depressive episode, were enrolled from 27 sites in the U

283 tor retardation during the most severe major depressive episode, whereas male twins reported more ins

284 rates for women who met criteria for a major depressive episode, which suggests an interaction betwee

285 Many patients with major depressive episodes who have an underlying but unrecogni

286 0 patients with three or more previous major depressive episodes who met remission criteria over a 2-

287 ied an additional 31% of patients with major depressive episodes who scored positive on the bipolarit

288 s examined associations between Wave 1 major depressive episode with manic episodes and other psychia

289 The current prevalence of major depressive episode with psychotic features was 0.4% (95%

290 polar disorder who achieved remission from a depressive episode with the addition of an antidepressan

291 he consequences of increased appetite during depressive episodes with atypical features are advocated

292 Major depressive episodes with psychotic features are relative

293 The study evaluated the prevalence of major depressive episodes with psychotic features in the gener

294 Resolution of major depressive episodes with residual subthreshold depressiv

295 al of 272 inpatients with at least one major depressive episode, with or without a history of a suici

296 with pleomorphic manifestations across major depressive episodes within individual patients with unip

297 therapy after recovery from bipolar II major depressive episode without an increase in hypomanic mood

298 .54%), and the prevalence of a current major depressive episode without psychotic features was 2.0% (

299 rst episode of mania who cycled into a major depressive episode without recovery from their index epi

300 at high genetic risk frequently experienced depressive episodes without major environmental stressor