ライフサイエンスコーパス: deprotonation

1 rface, activating the O-H bonds and inducing deprotonation.

2 wo Mn(II) and is enabled by a pKa 7.6 double deprotonation.

3 tion with visible light gated by protonation/deprotonation.

4 to proximity with protonated Glu325, causing deprotonation.

5 subject to acidic trapping and released upon deprotonation.

6 tereochemical course in the enantioselective deprotonation.

7 nvironment leading to an earlier Schiff base deprotonation.

8 stituted sulfone to override complex-induced deprotonation.

9 dride shift competitive with rehydration and deprotonation.

10 allylbenzene derivatives undergo reversible deprotonation.

11 yl groups shifted approximately -1.3 eV upon deprotonation.

12 of side-chain triazole units via protonation-deprotonation.

13 rials than liberate the free amine to effect deprotonation.

14 om the radical intermediate does not precede deprotonation.

15 ramethylpiperidine (TMP) furnished H2 ligand deprotonation.

16 osure and the regioselectivity of subsequent deprotonation.

17 increases with pH value through aqua ligand deprotonation.

18 orting the formation of radical species upon deprotonation.

19 lowed by oxidation to the tetraene and final deprotonation.

20 d Tyr-503, are positioned to facilitate this deprotonation.

21 on does not necessarily induce its concerted deprotonation.

22 orresponding to a pre-equilibrium of trypsin deprotonation.

23 action of this clamp in promoting substrate deprotonation.

24 ere reversible in the process of protonation/deprotonation.

25 The reaction is initiated by a rate-limiting deprotonation.

26 h displaces E148 and thereby facilitates its deprotonation.

27 ocking of each state achieved by protonation/deprotonation.

28 d to be involved in substrate hydroxyl group deprotonation, a critical requirement for subsequent oxy

29 After this initial deprotonation, A-1(O2') starts attacking the phosphate a

30 lusters is identified, which should follow a deprotonation activation pathway via a R'-C identical wi

31 zation through a sequence of selective gamma-deprotonation/alpha-alkylation and palladium(0)-catalyze

32 O-LUMO energy gaps suggest that, after their deprotonation, an increase in the electron delocalizatio

33 -range electron transfer is coupled to donor deprotonation and acceptor protonation is reported.

34 sequence controls the extent of Schiff base deprotonation and accumulation of intermediates, and thu

35 alpha-magnesiated nitriles can be formed by deprotonation and are configurationally stable at low te

36 h as the title compound undergo a mixture of deprotonation and complex formation in the presence of b

37 ed phenytoin preceded by comparatively rapid deprotonation and decomplexation reactions.

38 e absence of coordinating solvent (THF), the deprotonation and metalation exclusively afforded dinucl

39 Concomitant deprotonation and metalation of hexadentate ligand platf

40 othermic multistep process involving initial deprotonation and nitrite elimination, hydroxide attachm

41 rface reaction constants, namely, on silanol deprotonation and on cation binding.

42 hat the activation of the O2' nucleophile by deprotonation and orientation is less favorable with Na(

43 Complex 3 was prepared by deprotonation and oxidative homocoupling of an arsenide

44 h enable for the first time soft propargylic deprotonation and permit the bridging of a difference of

45 nteraction in which amphetamine induces CYAM deprotonation and release as a consequence of the H(+) c

46 Flash Photolysis was employed to measure the deprotonation and reprotonation rate constants of cyanid

47 D156 exhibits a substantial KIE (>2) in its deprotonation and reprotonation, which substantiates its

48 tionalization of compound 3e was possible by deprotonation and subsequent regioselective reaction wit

49 considered the energetics of the nucleophile deprotonation and the formation of a new P-O bond in aqu

50 ication of the strength of base required for deprotonation and the potential to correlate these data

51 the C3'* and H3O(+) formation via H3'-proton deprotonation and the subsequent C2'* formation via HF l

52 ease of their electron-donating ability upon deprotonation and to their stabilization in alkaline sol

53 roarene)AlCl(3) adduct formation followed by deprotonation and transmetalation.

54 onal discoveries are noteworthy: (i) for the deprotonation and trapping with Andersen's sulfinate, th

55 radical intermediate precedes or follows its deprotonation, and answering this question would offer c

56 minimize the Gibbs free energy for substrate deprotonation, and that the effects on reaction driving

57 g Ag salts enabling concerted C3-palladation-deprotonation, as explored by relevant experiments and s

58 a)]2-(mu-OH)}(3+) (1) can undergo reversible deprotonation at -30 degrees C to yield {[Cu(tmpa)]2-(mu

59 Key observations support the proposed deprotonation at C4 of the nascent polyketide by the cat

60 ors are readily prepared in good yields, and deprotonation at low temperature, in the presence of [Rh

61 Deprotonation at the 2-position to form a potassium enol

62 roposed mechanism for this reaction involves deprotonation at the alpha-carbon, intramolecular proton

63 ibed by a multisquare model with Schiff base deprotonation at the lumirhodopsin I intermediate stage.

64 lts in a much higher cumulative rotation and deprotonation barrier that effectively blocks PT to the

65 Such covalency is disrupted upon deprotonation but cannot be recovered fully upon formati

66 amates have been reported to be resistant to deprotonation by strong bases.

67 studies, wherein we observed that substrate deprotonation by the catalyst framework was necessary to

68 loop that relies on the coordination-coupled deprotonation (CCD) of a hydrazone switch has been devel

69 bon atom of coordinated micro-OCS2, which on deprotonation cleaves one C-S bond and simultaneously fo

70 cleavage occurs via the concerted metalation-deprotonation (CMD) mechanism in all types of reactions,

71 -H bond activation by a concerted metalation-deprotonation (CMD) mechanism involves precoordination o

72 H bond activation via a concerted metalation-deprotonation (CMD) mechanism, and (5) reprotonation of

73 e effects, typical of a concerted metalation-deprotonation (CMD) mechanism, were observed in the case

74 are in agreement with a concerted metalation deprotonation (CMD) pathway.

75 ional studies support a concerted metalation-deprotonation (CMD)-type ruthenation mode and shed light

76 assistance" (AMLA) and "concerted metalation deprotonation" (CMD) concepts.

77 The experimental thermochemical parameters (deprotonation DeltaG, DeltaH, and DeltaS) are in good ag

78 ambiguous support to the view that substrate deprotonation, driven by the His/Asp dyad, is an essenti

79 simulations suggested a model in which His58 deprotonation drives conformational changes that may mod

80 thesized from Weiss diketone by simultaneous deprotonation/electrophilic trapping of both oxo functio

81 Theoretical descriptors, such as deprotonation energies (DPE), rigorously account for Bro

82 The smaller deprotonation energies are associated with the stronger

83 by ourselves and others) correlate well with deprotonation energies from quantum mechanical (QM) and

84 O4-water chain could facilitate the initial deprotonation event in PSII.

85 in the crystals is influenced by protonation/deprotonation events with effective pKa values near ~5.5

86 s to OA were weak or absent, suggesting that deprotonation favors cellular interactions of fatty acid

87 dium hydroxide may be operative and an alpha deprotonation followed by alpha elimination of the di(3-

88 on by chloride abstraction and an enolate by deprotonation, followed by highly stereoselective C-C bo

89 precoordination of the C-H bond followed by deprotonation from an internal base.

90 Here, we demonstrate steering of deprotonation from symmetric acetylene molecules on subf

91 ormyl-2'-deoxyuridine that are ascribable to deprotonation from the C5-methyl group of 1 are observed

92 h we find a pH dependent competition between deprotonation from the methyl group at C5 and addition o

93 chemical processes, yet the barrier for its deprotonation has never been measured.

94 an those attributable to the C5-methyl group deprotonation in NMe-1.

95 tyryl)phenols 2a-9a were synthesized, and by deprotonation in solution, the solvatochromic phenolates

96 activation is not based on a single residue deprotonation in the IRR ectodomain but rather involves

97 th an apparent pKa = 8.0 +/- 0.1, indicating deprotonation in the rate-limiting step.

98 cruciforms exhibit a pronounced response to deprotonation in their UV/vis absorption and emission sp

99 ntially the alpha-amino radical is formed by deprotonation, in contrast to the formation of iminium i

100 a as a function of pH revealed that cytosine deprotonation is coupled to a syn-to-anti transition in

101 This deprotonation is facilitated by the coordination of the

102 is larger than in wild-type VAO, suggesting deprotonation is impaired in these variants.

103 The stabilization upon deprotonation is largest when a highly delocalized radic

104 ange 5.5-6.5 and they suggest that imidazole deprotonation is not a barrier to the folding of this pr

105 ies reveal that the initial site of catalyst deprotonation is not the H2IMes ligand, as the cyclometa

106 ion followed by aryl migration and reductive deprotonation is presented as a new reaction sequence in

107 After deprotonation, it extends toward the entire molecule, in

108 rium isotope effect and that glycolate alpha-deprotonation itself was only partially rate-limiting.

109 e-crystal X-ray diffraction study, the first deprotonation leads to a monoanionic dicarbollide ion th

110 Subsequent deprotonation leads to the isolation of the correspondin

111 ports an intramolecular concerted metalation-deprotonation mechanism with DeltaG(double dagger)(298K)

112 s proposed that the C-H cleavage occurs by a deprotonation mechanism.

113 iridium oxide occurs through an OOH-mediated deprotonation mechanism.

114 al carboxylate-assisted concerted metalation/deprotonation mechanism.

115 ich indisputably indicates that the proposed deprotonation occurs during the isomerization of U to Ps

116 ling studies indicate that the initial alpha-deprotonation occurs preferentially, but not exclusively

117 This catalytic pathway, where deprotonation occurs prior to oxidation, leads to an ove

118 Deprotonation of 1 by metal amides in the +2 oxidation s

119 Upon deprotonation of 11 and subsequent addition of benzyl cy

120 rther corroborated by reversible protonation/deprotonation of 7e (R(1) = NMe2, R(2) = H) for which th

121 Deprotonation of [U(Tren(TIPS))(NH2)] (1) [Tren(TIPS) =

122 the cytoplasmic half-channel and subsequent deprotonation of a Glu residue at a luminal half-channel

123 ryne intermediate occurs primarily via ortho-deprotonation of a L.Pd(Ar)OTf (L = biaryl monophosphine

124 .7) important for catalysis, consistent with deprotonation of a metal-bound water nucleophile.

125 ule can be accessed by the sequential double deprotonation of a mono-nido-carboranyl imidazolium zwit

126 uperoxide reacts with substrate activated by deprotonation of a phenol group at position 4 of the sub

127 ch a catalysis acts as a general base in the deprotonation of a water molecule involved in the cleava

128 Deprotonation of alphaY190 by a nearby lysine strengthen

129 s delocalization dramatically stabilizes the deprotonation of an active-site tyrosine residue, result

130 terionic quinine-derived entity generated by deprotonation of an ammonium salt with the anionic react

131 Deprotonation of an anionic imidazolium salt with lithiu

132 external strong base to generate the NHC by deprotonation of an azolium salt.

133 nism of enamine formation via intramolecular deprotonation of an iminium carboxylate intermediate.

134 yne intermediates are generated by ortho-C-H deprotonation of aryl(mesityl)iodonium salt with a comme

135 l pH that are caused by activation and thiol deprotonation of beta-subunit cysteines.

136 rate through a glycal intermediate formed by deprotonation of C2'.

137 Observations support the deprotonation of carboxyl groups with low acid dissociat

138 BE = 287.9 +/- 0.3 proved to reliably assess deprotonation of carboxyl groups.

139 of gem-diol to carboxylic acid (Step 3); and deprotonation of carboxylic acid to carboxylate anion un

140 iolate to the GSSG-disulfide followed by the deprotonation of Cys56-thiol by Glu47-carboxylate and (i

141 In contrast, deprotonation of D396 and absence of ATP introduce flexi

142 lence bond calculations of the TIM-catalyzed deprotonation of DHAP and GAP by both wild-type TIM and

143 rom 20 ns to 5 ms is incompatible with early deprotonation of E90.

144 which themselves were prepared by Hoppe-Beak deprotonation of ethyl 2,4,6-triisopropyl-benzoate with

145 By contrast, in single-stranded DNA, deprotonation of G(*+) and the irreversible escape of th

146 irectly initiate this polymerization through deprotonation of gamma-BL to generate reactive enolate s

147 is attributable to a chemical reaction, the deprotonation of glutamic acid 148 (E148).

148 Compound I, and in mediating stereospecific deprotonation of H-3re of the substrate.

149 n of precursor salts to give neutral NHCs or deprotonation of heterocyclic mesomeric betaines to give

150 heterocyclic salts and (ii) anionic NHCs by deprotonation of heterocyclic mesomeric betaines.

151 i) neutral N-heterocyclic carbenes (NHCs) by deprotonation of heterocyclic salts and (ii) anionic NHC

152 esign of selective transformations involving deprotonation of high-energy intermediates.

153 rough the channel, including the protonation/deprotonation of His37, are explicitly considered using

154 w that pHi increase activates FAK by causing deprotonation of histidine 58 in its FERM (band 4.1, ezr

155 l as a function of pH were controlled by the deprotonation of hydrated sulfur dioxide, SO2.H2O, which

156 While the yield of the deprotonation of hydrocarbons has been successfully mani

157 ain (99)Tc(V)O2-NHC complexes is the in situ deprotonation of imidazolium salts, enabling the prepara

158 These catalysts mediate the deprotonation of imines and direct the 2-azaallyl anions

159 ion with theoretical calculations reveal the deprotonation of iminium intermediates as the dominant p

160 ngths correlate closely with the energies of deprotonation of isolated molecules into isolated anions

161 were passivated with polybases to induce the deprotonation of its methylammonium ions (MA(+)).

162 g and transmembrane helices H5 and H6, while deprotonation of its protonated Schiff's base triggers t

163 Deprotonation of K165 underlies the alkaline block.

164 ct more effective charge reorganization upon deprotonation of Mo than W POM clusters and the much wea

165 Possible deprotonation of more acidic receptors of each compound

166 The enantioselective deprotonation of N,N-diisopropy-1-methylcyclopropanecarb

167 We report the enantioselective, lateral deprotonation of ortho-protected or functionalized terti

168 nd oxazolidinones, which excludes the direct deprotonation of oxazolidinones via E2 mechanism.

169 p-oxidophenylnitrene formed by dissociative deprotonation of p-azidophenol indicate either a triplet

170 ituted phenylnitrene, formed by dissociative deprotonation of p-azidotoluene, with CS(2) and NO indic

171 pendent manner in a mechanism that resembles deprotonation of PA.

172 terocyclic carbene (NHC) formation either by deprotonation of precursor salts to give neutral NHCs or

173 ctions depends on the following factors: (1) deprotonation of pro-R or pro-S-H, (2) equilibration of

174 ed pathway that involves photoionization and deprotonation of radical cation, followed by homolytic c

175 manner, is effective for the regioselective deprotonation of sensitive diazines in hydrocarbon solut

176 in response to the pH change, interpreted as deprotonation of silanol groups on the silica gel surfac

177 on of the aryl halide PhI to Pd(0)/PCy3, (2) deprotonation of SM by CsF to form DG' = [EtCON-Ar]Cs(+)

178 issolution of solid doxorubicin, protonation/deprotonation of soluble doxorubicin, and passive transp

179 negative ion formation in the ESI source via deprotonation of substituted phenols and benzoic acids a

180 e of continuous-flow methods has allowed the deprotonation of TFPO and subsequent zincation at higher

181 -CH2. presumably arising at copper oxidation/deprotonation of the 1-NMe2 group.

182 presumably arising at copper oxidation/deprotonation of the 1-NMe2 group.

183 g it can serve as a Lewis acid to facilitate deprotonation of the 2'-hydroxyl.

184 e the anionic intermediate that results from deprotonation of the 5-hydroxyl group by histidine-267.

185 In such species, deprotonation of the acid fragment can stabilize the rem

186 at the catalatic reaction of KatG's involves deprotonation of the active-site Trp, which plays a role

187 ut) acts as an electronic switch, triggering deprotonation of the adduct Trp.

188 Although deprotonation of the alpha-hydroxyalkyl radical has been

189 Deprotonation of the As-H bonds in 2 by nBuLi produces [

190 In GtCCR2, deprotonation of the Asp-96 homolog is required for cati

191 and-cooperation pathway in which an internal deprotonation of the benzylic position by the eta(1)-CO2

192 necessary to accomplish rapid borylation by deprotonation of the borylated arenium cation (sigma com

193 ural MFM-300(V(IV)), [V(IV)2O2(L)], in which deprotonation of the bridging hydroxyl groups occurs.

194 tructure suggests sequential protonation and deprotonation of the c-ring, with ATP-hydrolysis-driven

195 n of the carboxylate anion occurs via direct deprotonation of the carboxylic acid under base (Step 4)

196 Light-induced deprotonation of the chromophore phenolic oxygen in the

197 carbodicyclopropenylidene (2) is accessed by deprotonation of the corresponding triafulvene cycloprop

198 ad, cleavage of the H-H bond is achieved via deprotonation of the eta(2)-H2 ligand within a cationic

199 observed perturbation with that expected for deprotonation of the Fe1-coordinated water ligand.

200 Large excess addition of F(-) promotes deprotonation of the ground-state complex, according to

201 Heterolysis of the Si-H bond, deprotonation of the heteroarene, addition of the hetero

202 erates the rate of catalysis by facilitating deprotonation of the hydrogen addition product before ox

203 displacements, the second of which requires deprotonation of the indole nitrogen in Trp during its a

204 re is presented based on the STM tip-induced deprotonation of the inner protons of individual macrocy

205 rted unusual reductive protonation/oxidative deprotonation of the metal centers may serve as a new ch

206 ct of TBAF can be rationalized in terms of a deprotonation of the monoamino-tribromo-NDI generated in

207 ns suggests that this change is triggered by deprotonation of the mu-hydroxo bridge.

208 roups in GLP-1 suggest it is the protonation/deprotonation of the N-terminus that is responsible for

209 Upon deprotonation of the NH group, a C6F5-substituted formaz

210 acid, a Bronsted base, or both to facilitate deprotonation of the nucleophile.

211 erization of lignin is initiated through the deprotonation of the para-hydroxyl group of monolignols.

212 Deprotonation of the parent titanium imido ((tBu)nacnac)

213 es provide evidence that rearomatization via deprotonation of the pentahydro-beta-carbolinium ion int

214 e via a sequential mechanism involving first deprotonation of the phenol/naphthol, followed by the pr

215 Deprotonation of the phenolic proton in this complex res

216 as well as 4 equiv of methane, 2 equiv from deprotonation of the phosphine and 2 equiv from C-H bond

217 H-dependent electrochemistry associated with deprotonation of the phosphonic acid groups.

218 Selective deprotonation of the pro-S P-phenyl ring of 5 was ascert

219 cm(-1) The first contribution corresponds to deprotonation of the proton release complex (PRC), a com

220 eps that are associated with protonation and deprotonation of the pump site, and point to the area ar

221 dopsin structure in silico, and we find that deprotonation of the retinyl is likely to be responsible

222 in an L-like intermediate that precedes the deprotonation of the retinylidene Schiff base (i.e., for

223 The influence of the deprotonation of the ring B hydroxyl moiety is related t

224 sins, opening of the channel occurs prior to deprotonation of the Schiff base.

225 s the oxidation product, reasonably due to a deprotonation of the sulfide radical cations.

226 dopalladation pathway with turnover-limiting deprotonation of the sulfonamide nucleophile and a trans

227 between CTA(+) and -COO(-) (derived from the deprotonation of the terminal carboxyl group of MHA).

228 Deprotonation of the thiol gives a protonated amine that

229 After CH-deprotonation of the triazole and the triazolium, powerf

230 Deprotonation of the triiron parent imido ((tbs)L)Fe3(mu

231 on also leads to a change in mechanism, with deprotonation of the water nucleophile requiring a close

232 Deprotonation of the yttrium-arsine complex [Cp'3Y{As(H)

233 es) undergo migratory ring expansion through deprotonation of their benzylic urea derivatives with li

234 Deprotonation of these salts with (Z)-configuration gave

235 Deprotonation of thioureas by sodium, potassium or imida

236 Subsequent deprotonation of this monoanion leads to the first N-dic

237 ironmental pH changes due to the protonation/deprotonation of TIA-1 RRM3 histidine residues.

238 of DrrA functions as the catalytic base for deprotonation of Tyr77 of Rab1b to enable nucleophilic a

239 A (6 equiv) in CPME at -60 degrees C enables deprotonation of unactivated secondary dialkyl TIB ester

240 Here we report that the deprotonation of ureas generates a class of versatile ca

241 ron transfer is facilitated by base assisted deprotonation of water.

242 omplexes [W( identical withCPHR)(CO)2(Tp*)], deprotonation of which provides the anionic phosphaisoni

243 Protonation (deprotonation) of the Cys ligand often accompanies redox

244 Alternate scenarios, such as catalyst deprotonation or the in situ formation of a neutral chir

245 etwork usually exhibit volume expansion upon deprotonation or volume contraction when being heated.

246 ach reliably shown to affect selectivity for deprotonation over alkylation.

247 s, presumably through a concerted metalation-deprotonation pathway.

248 on analyses of the transition structures for deprotonation predicted using density functional theory

249 level showed that the stereoselective ortho deprotonation process fulfills the features of the CIPE

250 ted absorption band that was attributed to a deprotonation process involving the amine moiety of the

251 y pH dependent, which can be attributed to a deprotonation process of the Ni-based OECs, leading to t

252 s can be accessed in 99:1 er from asymmetric deprotonation protocols without the use of (-)-sparteine

253 We measure the deprotonation/protonation barriers of 0.36 eV and find t

254 lyst-substrate complex via a cyclometalation deprotonation provides a five-membered nickelacycle inte

255 chemoselective metal-heteroatom exchange or deprotonation, provides a new approach to cyclic ethers.

256 The deprotonation rate constant decreases with decreasing wa

257 It was found that the deprotonation rate constant kd decreases with decreasing

258 h to determine site-specific protonation and deprotonation rate constants (kon and koff, respectively

259 or more conveniently generated in situ by a deprotonation reaction involving its readily prepared py

260 the catalytic base facilitating the terminal deprotonation reaction is discussed.

261 the stereochemistry-determining step is the deprotonation reaction, and a model based on a deprotona

262 The regioselectivity of deprotonation reactions between arene substrates and bas

263 o a single lower charge state via sequential deprotonation reactions with a proton scavenging reagent

264 ral phenyl ring, after triple imidazolium C2 deprotonation reacts in a one-pot reaction with Pd(OAc)2

265 the retinal trans-cis isomerization and the deprotonation/reprotonation of the Schiff base, are coup

266 rmation of cellobiitol demonstrated that the deprotonation/reprotonation step is coupled with rotatio

267 unveil a one-base catalytic mechanism of C2 deprotonation/reprotonation via an enolate intermediate

268 sulfides release H2S upon reduction and that deprotonation results in disproportionation to the paren

269 in >/=99:1 dr and >/=99:1 er via asymmetric deprotonation (s-BuLi/chiral diamine) and trapping with

270 chromophore (namely, local solvation at the deprotonation site and a partial flexibility of the prot

271 61K mutation in proximity to the protonation/deprotonation site is considered.

272 The deprotonation site of p-hydroxybenzoic acid upon electro

273 on of the three-membered ring is the favored deprotonation site.

274 ges, the number of Cu(I) or Cu(II) ions, the deprotonation sites, and likely Cu(I/II) coordination of

275 cess in which enantioinduction occurs in the deprotonation step (Scheme 11 ).

276 the catalyst-mediated alpha-tosyloxy ketone deprotonation step to form an enantiodiscriminant oxy-al

277 as MgCl2 and dicyclohexylmethylamine for the deprotonation step, an excellent functional group tolera

278 ting the Schiff base reorientation after the deprotonation step.

279 termining electron-transfer step followed by deprotonation steps.

280 ed conditions involving a key "shuttle base" deprotonation strategy was applied to the synthesis, in

281 Substrate deprotonation studies under transient-state conditions s

282 e human rhodopsin exhibited more Schiff base deprotonation than bovine rhodopsin, which could arise f

283 cing the bound water, followed by sequential deprotonation through a copper-hydride intermediate to r

284 (cosubstrate)-PKMT-substrate complex, lysine deprotonation through dynamic water channels, and a nucl

285 hydride addition to re-form an alkane or by deprotonation to form an alkene and H2 .

286 (2) with three protons has the potential of deprotonation to form energetic salts.

287 The deprotonation to give the organolithium was optimized by

288 onic tetrads, consistent with faster forward deprotonation to the C terminus.

289 for activity and strongly suggest that Tyr21 deprotonation, to form the reactive nucleophilic phenoxi

290 at C-H activation via a concerted metalation-deprotonation transition state is facilitated by the pre

291 d (c) a proton acceptor accelerating the C-H deprotonation via the CMD mechanism; and (4) revealing t

292 inary evidence suggests that the protonation/deprotonation voltammetric wave involves physisorbed rat

293 rted reaction involving coordinated Tyr ring deprotonation where Cu(II) coordination enables formatio

294 e H(+) electrochemical gradient (microH+) is deprotonation, whereas in the presence of microH+, the l

295 he activation step is enabled by a pKa > 8.6 deprotonation, which is assigned to Mn(II)-bound H2O; it

296 Tf (X = Cl (1), F (4); OTf = CF3SO3) undergo deprotonation with KO(t)Bu to afford the trans-halide-al

297 Subsequent deprotonation with LiN(SiMe3 )2 affords the fluoroalkyny

298 fluorobenzenesulfonimide enabled via in situ deprotonation with lithium 2,2,6,6-tetramethylpiperidine

299 ne step from free N-heterocyclic carbenes by deprotonation with n-butyl lithium followed by borane ad

300 version to a bisboron difluoride complex via deprotonation with NaH and treatment with BF3 acts to lo