ライフサイエンスコーパス: derange

1 proteolytic activity of these organelles was deranged.

2 after the first round of DNA synthesis were deranged.

3 ed responses of mature B cells are seriously deranged.

4 Coronary flow in patients with HCM is deranged.

5 clei assembled in the depleted extracts were deranged.

6 not only a window into how brain function is deranged after structural damage, but also offers the pr

7 use extreme preterm birth is associated with deranged alveolar structure in infancy, the most likely

8 Because perichondrium becomes deranged and interrupted by cartilaginous outgrowths in

9 of the determinants of the serum sodium are deranged and what is the underlying culprit?

10 sensory inputs, the polarity of movement is deranged, and backward peristaltic waves predominate at

11 The underlying cartilaginous epiphysis was deranged as well and displayed random patterns of cell p

12 tients, unilateral electrical activity might derange autonomic balance between both hemispheres and c

13 ogically raised synaptic dopamine levels and deranged basal ganglia opioid transmission.This, rather

14 leaflet redundancy was associated with these deranged biochemical measures (p <0.03).

15 ric features that might collectively reflect deranged body schema processing.

16 Our results indicate that deranged Ca(2+) signaling may play an important role in

17 andling proteins are thought to underlie the deranged Ca(2+) transients that contribute to deteriorat

18 vascular calcification occurs in response to deranged calcium and phosphate metabolism and is charact

19 Deranged CaMKII-dependent titin phosphorylation occurs i

20 We reveal deranged cardiac function of a zebrafish model of cardio

21 Deranged cardiac metabolism and abnormal redox state dur

22 o explore the mechanisms associated with the deranged CBF autoregulation in ALF.

23 However, the overabundant lysosomes derange cellular metabolism by consuming the key glycoly

24 and traumatic brain injury, that may involve deranged cellular chloride homeostasis.

25 d diffuse cerebral edema on imaging and more deranged cerebral hemodynamics.

26 Abnormalities in this pathway result in deranged ciliogenesis and polycystic kidney disease.

27 Age-induced dermal atrophy with deranged collagen structural organization was prevented

28 Deranged concentrations of humoral factors are not only

29 ytes ensures a normal cardiac function while deranged contraction of cardiomyocytes can lead to heart

30 MMP-9 activity in dry eyes may contribute to deranged corneal epithelial barrier function, increased

31 ect-indirect pathways, our data suggest that deranged cortico-subthalamic transmission via the NMDA r

32 n locomotor deficits, even in the absence of deranged dopaminergic innervation.

33 In obesity, cardiac energetics are further deranged during inotropic stress, in association with co

34 The pattern of growth is deranged: emergence of the first mitotic bud is delayed,

35 Because deranged endothelial function and coagulation pathways c

36 Current evidence suggests that deranged energy storage in femoral-gluteal and other per

37 in the composition of gut microflora and/or deranged epithelial barrier function elicits pathologic

38 cystic fibrosis, a disease characterized by deranged epithelial Cl(-) flux.

39 t infection of erythroid precursor cells and deranged erythropoiesis in patients with HIV-1 infection

40 t the syn conformation in each case to avoid deranging essential protein-DNA interactions.

41 layers during mammalian development, and its deranged expression is associated with vascular injury a

42 te to severe) were independent predictors of deranged function.

43 The deferred implantation and deranged gestational development in Pla2g4a-/- mice were

44 r AMP-activated protein kinase (AMPK) led to deranged glucose metabolism and redox homeostasis, resul

45 injury and inflammation, decreased glycemia, deranged hepatic TCA cycle intermediate concentrations,

46 ion throughout the islet could contribute to deranged hormone secretion in some forms of type 2 diabe

47 ate (HS) and syndecans, we speculated that a deranged HS/syndecans regulation impairs FGF-2 activity.

48 haKlotho, a multiorgan endocrine network, is deranged in a self-amplifying vortex resulting in organ

49 Iron metabolism and transport are severely deranged in ACLF patients and more so in those with MOF.

50 r development and homeostasis that are often deranged in cancer.

51 showed that an insulin signaling pathway is deranged in different locations in NAFLD patients.

52 This process can become deranged in diseased blood vessels, such as coronary art

53 mic nervous control of the heart is markedly deranged in patients late after the Fontan operation, wi

54 led that cortico-subthalamic transmission is deranged in PD and directly responsible for the excessiv

55 , environmental sounds and music, and may be deranged in two ways.

56 recent work on hepatic SEIRR indicating that deranged insulin signaling may have a remarkably simple

57 causes hepatic insulin resistance along with deranged insulin signaling, leading to hyperglycemia and

58 We propose that deranged intestinal and hepatic lipid metabolism and def

59 normalized ratio was normal or only modestly deranged (</= 2.5).

60 However, treatment directed at deranged metabolic control in diabetes is effective only

61 ological features, DMD muscles show severely deranged metabolic gene regulation and mitochondrial dys

62 Defective autophagy and deranged metabolic pathways are common in cancer; pharma

63 treatment, and occurred in conjunction with deranged mitochondria, areas of necrosis, and prominent

64 creased mitochondrial membrane potential and deranged mitochondrial ultra-structure in these model sy

65 olce-/- tendon, 100% of collagen fibrils had deranged morphologies, indicating marked functional effe

66 t in renal function, could contribute to the deranged NaCl and water excretion that often leads to vo

67 and bacterial translocation associated with deranged neutrophil activity.

68 y short hyperoxic exposure was sufficient to derange normal chemoafferent development.

69 5)) phenylalanine in eight CHD patients with deranged nutritional status before, during, and after HD

70 lism predispose chronic HD (CHD) patients to deranged nutritional status, which is associated with po

71 lementation are needed for CHD patients with deranged nutritional status.

72 Furthermore, the data indicate that deranged oxygen sensing--not a loss of EPO production ca

73 in sway may be, at least partly, mediated by deranged peripheral and central somatosensory signals fr

74 Sixty-four percent of the patients with a deranged physiologic parameter died in hospital compared

75 The presence of a deranged physiologic parameter was associated with morta

76 Every individual deranged physiologic parameter was associated with morta

77 anged physiologic parameters (odds ratio per deranged physiologic parameter, 2.24 [1.53-3.26]).

78 t admission, 69% of patients had one or more deranged physiologic parameter.

79 ortality increased with increasing number of deranged physiologic parameters (odds ratio per deranged

80 As a measure of illness severity, single deranged physiologic parameters are as useful as a compo

81 Single deranged physiologic parameters at admission are associa

82 Cutoffs for deranged physiologic parameters were defined a priori an

83 ese different forms of sleep disruption show deranged physiology from subcellular levels to complex a

84 may be therapeutic for cancer patients with deranged PI3K signaling.

85 sed strain represents a mechanical analog of deranged post-translational modification of titin that r

86 These deranged processes culminate in an exuberant proliferati

87 aspects of native developmental programs for deranged proliferation, adaptation, and tolerance.

88 provide a valuable approach for normalizing deranged protein anabolism associated with human disease

89 tory failure from sympathetic denervation or deranged reflexive regulation of sympathetic outflows.

90 milieu, increased mitochondrial metabolism, deranged regulation of beta-cell cytoplasmic free Ca(2+)

91 ssociated with mitochondrial dysfunction and deranged regulation of metabolic genes.

92 Autosomal genes often showed deranged regulatory levels, indicating they were in path

93 ver, these biopsies were performed to assess deranged renal function; therefore, the specimens may re

94 derlying mechanism on how insulin deficiency deranges skeletal muscle mitochondrial physiology remain

95 tude of Ca2+ transients induced by I(Ca) and deranged the smoothly graded I(Ca)-SR Ca2+ release relat

96 ietary lipids causes inflammatory responses, deranges the homeostasis of cellular metabolism, and is

97 les blocks initiation of DNA replication and deranges the mitotic checkpoint, a phenotype consistent

98 ngs in intrathoracic pressure resulting from deranged ventilatory mechanics are the most likely cause

99 on hour, those during the 7 AM hour had more deranged vital signs, were more likely to have a respira

100 netically programmed process that can become deranged when the components of the cellular apoptotic m