ライフサイエンスコーパス: deregulate

1 is, both pathways, namely IRAK and Rip2, are deregulated.

2 MI1 is overexpressed or the PRC1 activity is deregulated.

3 ously revealed how disease-causing mutations deregulate a subtle dynamic conformational equilibrium i

4 A sequencing demonstrates that FA deficiency deregulates a network of genes involved in immune functi

5 While the deregulated activation of DNMT1 or KIT has been implicat

6 naling via type I interferon receptor led to deregulated activation of group 2 innate lymphoid cells

7 This reduced viability is associated with deregulated activation of the immune deficiency (IMD) pa

8 e results in increased H4K16 acetylation and deregulated activation of the myogenic program in SCs.

9 d with wild-type TnpA, these mutants exhibit deregulated activities.

10 mune disease attributed in large part to the deregulated activity of Nfkappab1(-/-)Fo B cells that pr

11 Deregulated AKT kinase activity due to PTEN deficiency i

12 enol-induced hypertrophy), likely because of deregulated Akt/mTOR activity.

13 mature T-ALL, JAK3/STAT5B mutations in HOXA1 deregulated ALL, PTPN2 mutations in TLX1 deregulated T-A

14 ted T-ALL, and PIK3R1/PTEN mutations in TAL1 deregulated ALL, which suggests that different signaling

15 ic agents for human diseases associated with deregulated alpha-N-terminal methylation.

16 ession of long non-coding RNAs (lncRNAs) are deregulated and closely associated with prognosis.

17 n in the prenatal period were epigenetically deregulated and could be linked with wheezing later in c

18 veral human pathologies are characterized by deregulated angiogenesis and unstable blood vessels.

19 However, it is unclear whether deregulated AS directly contributes to disease.

20 l to reveal novel mechanisms of how CEBPA is deregulated at the transcriptional level.

21 In Redd1(-/-) mice, deregulated ATG4B activity and disabled autophagic flux

22 unknown oncogenic property of the spatially deregulated AURKA in tumorigenesis and provide a potenti

23 les to lipid rafts is a dominant strategy to deregulate autophagy in the context of HTLV-1 transforma

24 ht be required for the oncogenic activity of deregulated BCL6 expression.

25 APC deletion deregulates beta-catenin, leads to high Wnt tone, and di

26 hown previously to cleave human Factor V and deregulate blood coagulation, as the most abundant type

27 len tube-female gametophyte contact, thereby deregulating BUPS-ANXUR signaling and in turn leading to

28 of the UPS that have been demonstrated to be deregulated by a variety of mechanisms in hematologic ma

29 irmed a high prevalence of genes known to be deregulated by aberrant methylation in HCC (e.g., Ras as

30 iated chemoresistance in cancer cells can be deregulated by altering NO homeostasis.

31 MECOM (also known as EVI1) proto-oncogene is deregulated by chromosomal translocations in some cases

32 CK2 provoked by p53 ablation and irrevocably deregulated by NHEJ inactivation.

33 ovel insights on how these mechanisms may be deregulated by oncoproteins or mutations/variants in CEB

34 rice leaves, and that the interaction can be deregulated by salicylic acid (SA).

35 inal-B (Abd-B) represents one of the targets deregulated by several SR-miRNAs.

36 of dozens of proteins that are consistently deregulated by T21.

37 scriptomics, the cellular functions that are deregulated by the microbiome in disease can now be comp

38 analysis identified multiple genes that were deregulated by Trex2 loss after treatment with IMQ.

39 le that inhibiting IP3R3 degradation in PTEN-deregulated cancers represents a valid therapeutic strat

40 To uncover the mechanisms relevant to deregulated cell division in human glioma stem cells, we

41 nd Rac1 knockdown significantly restored the deregulated cell growth induced by TIPE1 small interferi

42 uces a decrease of H3K36(me2), especially in deregulated cell-cycle-related genes.

43 Many cancer-associated mutations that deregulate cellular metabolic responses to hypoxia also

44 Deregulated cellular metabolism is a hallmark of tumors.

45 It would be worthwhile to explore deregulated cellular programs of SMZL as therapeutic tar

46 As a result of deregulated cellular signaling pathways, cancer cells of

47 ward more productive trafficking pathways by deregulating cellular degradation mechanisms.

48 tiple pathways, (ii) contain bidirectionally deregulated components, (iii) are confined to a pathway

49 We previously reported that deregulated cyclin E activity causes defective terminal

50 E2F-2 deletion; however, anemia in mice with deregulated cyclin E is not improved by E2F-2-loss, whic

51 a network of targets associated with STAT3, deregulate cytokine-mediated gene activation, suppress a

52 nction share a similar pathogenic pathway in deregulating DAergic neuron SV endocytosis and that they

53 anscriptional control in key B cell pathways deregulated differentially in Burkitt lymphoma and other

54 fects, recurrent genomic rearrangements, and deregulated DNA integrity checkpoints, reminiscent of hu

55 basis for genome instability resulting from deregulated DNA replication, observed in cancer and othe

56 by initiating a cumulative genotoxicity that deregulated DNA synthesis.

57 constituting no more than half of all genes deregulated during tumor progression and an even smaller

58 reveal how disease-causing mutations in p97 deregulate dynamics of the N-terminal domain that binds

59 t circulating TGF-beta1-regulated miRNAs are deregulated early in T1D patients who are at risk for ra

60 s central to epithelial cell physiology, and deregulated EGFR signaling has an important role in a va

61 ng EGFR accumulation in the nucleus, thereby deregulating EGFR signaling by two distinct mechanisms.

62 causal role in mood-related phenotypes, (2) deregulated EIF2-mediated protein translation may repres

63 and its epigenetic LXRalpha target that when deregulated enables pathogenic pulmonary fibrosis.

64 usly expressing the gas vesicle cluster in a deregulated environment, gas vesicles can occupy around

65 Mounting evidence implicates deregulated ephrin function in multiple aspects of tumor

66 This resulted in deregulated EPOR expression, hypersensitivity to erythro

67 Mechanistic studies of deregulated ERG in prostate cancer and other cancers con

68 eficiency in basal keratinocytes resulted in deregulated expression of dihydrolipoamide acetyltransfe

69 Additionally, we found deregulated expression of proteins with relevant functio

70 Deregulated expression of these genes is linked to the i

71 For many years, it has been established that deregulated expression of transcription factors, impairm

72 arcinoma-associated fibroblasts, implicating deregulated expression of tRNAi(Met) in the tumor stroma

73 in lesions correlates with parakeratosis and deregulated expression or location of most of the autoph

74 g of MSI1 to its endogenous targets, thereby deregulating expression of factors implicated in neural

75 Deregulated extracellular signal-regulated kinase (ERK)

76 hromatin structure profiling to identify the deregulated factors on which cancer cells depend, with t

77 Given that deregulated fatty acid metabolism plays a key role in ki

78 Thus deregulated FGFR signalling has an important role in ost

79 ed that the c-Myc transcriptional network is deregulated following JMJD1A inhibition.

80 Transgenic mice deregulated for cyclin E in the mammary epithelia develo

81 We also discuss the effects of deregulated fork resection on genomic instability and on

82 e formation and mitotic catastrophe and that deregulated FOXM1 and KIF20A expression may confer pacli

83 DSB accumulation, checkpoint activation, and deregulated G2/M progression and by enhancing the replic

84 tion of genes is an alternative mechanism to deregulate gene expression in a wide range of diseases.

85 ly in white and brown preadipocytes leads to deregulated gene expression and blocks differentiation t

86 f epigenetic networks to correct abnormal or deregulated gene expression as a strategy to alleviate t

87 Many of the deregulated genes are associated with extracellular matr

88 Among the shared deregulated genes between mouse and human are important

89 sequencing to explore the changed miRNAs and deregulated genes in the spleen of three groups of broil

90 RNA sequencing analysis revealed a number of deregulated genes involved in cell survival, migration,

91 g in endoplasmic reticulum, as well as novel deregulated genes such as ALCAM that is prognostically r

92 AML) is induced by the cooperative action of deregulated genes that perturb self-renewal, proliferati

93 ed almost normal transcriptome, with only 38 deregulated genes vs normal PCs; these included a few tu

94 enable more precise identification of cancer-deregulated genes, allow for early identification of the

95 overy in expression of a large proportion of deregulated genes.

96 errant expression of noncoding RNAs (ncRNAs) deregulates genes involved in B cell differentiation via

97 Chromosomal rearrangements deregulating hematopoietic transcription factors are com

98 the effect of aPKC on transformed growth by deregulating Hippo/Yap1 signaling may be clinically rele

99 This work also suggests that deregulated Hmga1 perturbs this equilibrium during intes

100 peutic value because the accumulation of the deregulated, hyperactive Cdk5/p25 complex in human brain

101 l approach to treat cancers characterized by deregulated hypoxia signaling or redox imbalance.

102 Current concepts invoke a deregulated immune reaction involving features of hyperi

103 characterized by a dysbiotic microbiota and deregulated immune response and resulting in tooth loss

104 e aetiology of IBD is partly attributed to a deregulated immune response to gut microbiome dysbiosis.

105 opposite of these antisense genes were also deregulated in 42% of the observed sense-antisense gene

106 MYC proteins are overexpressed or deregulated in a majority of malignancies and drive tumo

107 thway involved in cell-cycle control that is deregulated in a number of cancers.

108 We identified 63 miRNAs deregulated in a statistically significant way.

109 G9a is genetically deregulated in a variety of tumor types and can silence

110 Phosphoinositide 3-kinase (PI3K) is deregulated in a wide variety of human tumors and trigge

111 opoietic stem cell expansion and is commonly deregulated in acute leukemias.

112 terminant for gene expression and frequently deregulated in acute myeloid leukaemia (AML).

113 L-XL(+) /myeloid cell leukemia 1+ signature, deregulated in Alb-R26(Met) tumors, characterizes a subg

114 Notably, we demonstrated IRF4 to be deregulated in B cells from common variable immunodefici

115 olesterol-5,6-epoxide (5,6-EC) metabolism is deregulated in BC but the molecular origin of this is un

116 thma (ovalbumin and house dust mite); miRNAs deregulated in both models were further tested in a huma

117 MicroRNAs (miRNAs) are often deregulated in cancer and are thought to play an importa

118 ETS transcription factors are commonly deregulated in cancer by chromosomal translocation, over

119 They are specifically deregulated in cancer cells and contain regulators that

120 ions suggest that beta-globin is selectively deregulated in cancer cells, mediating a cytoprotective

121 er as oncomiRs or tumor suppressive miRs are deregulated in cancer cells.

122 rofiling technique distinguished genes truly deregulated in cancer from genes that identify cellular

123 he initiator methionine tRNA (tRNAi(Met)) is deregulated in cancer.

124 mor suppressor genes, these processes become deregulated in cancer.

125 and TP53 regulatory networks are frequently deregulated in cancer.

126 regulators of gene expression and are often deregulated in cancer.

127 In conclusion, the Hh pathway is deregulated in CML stem and progenitor cells.

128 mTOR signaling is deregulated in common diseases, like cancer and epilepsy

129 for targeting pathways that are specifically deregulated in different tumors.

130 nvolved in cell and tissue integrity that is deregulated in different types of cancer.

131 an communication network (ICN) and how it is deregulated in disease.

132 hanisms for cell phenotype, and is a process deregulated in disease.

133 The expression of leukotriene receptors was deregulated in esophageal squamous cell cancer.

134 This form of plasticity is deregulated in Fragile X Syndrome, a monogenic form of a

135 gammac) family of cytokines, are prominently deregulated in HAM/TSP and underlie many of the characte

136 e signature consisting of 935 genes commonly deregulated in HCC as compared with the surrounding nont

137 es involved in sphingolipid metabolism to be deregulated in HNF1A deficiency: Ormdl1, sphingosine kin

138 key to normal development and are frequently deregulated in human cancer.

139 , proliferation and metabolism, and is often deregulated in human cancer.

140 ncer therapeutics, since they are frequently deregulated in human cancers and contribute to sustained

141 Myc transcriptional activity is frequently deregulated in human cancers, but a Myc-driven gene sign

142 s a conserved regulator of organ size and is deregulated in human cancers.

143 re conserved in humans and specific ones are deregulated in human-induced pluripotent stem cell-deriv

144 Only a subset of functions deregulated in initial tumors was similarly deregulated

145 It is commonly deregulated in leukemia.

146 NSE levels were deregulated in leukemias and were influenced by the iden

147 drivers of cell proliferation, are commonly deregulated in lung cancer where they may serve as oncog

148 TNKS are deregulated in many different cancer types, and inhibiti

149 onds to diverse environmental signals and is deregulated in many human diseases, including cancer and

150 range of cues, and its signaling pathway is deregulated in many human diseases.

151 t the pattern of miRNAs expression is highly deregulated in MPM and that a 2-miRNA signature can be a

152 disclosing the pathways that are molecularly deregulated in NMZL and we compare the molecular profile

153 ein kinase) signalling pathway is frequently deregulated in non-small-cell lung cancer, often through

154 d by NRF2, a transcription factor frequently deregulated in NSCLC.

155 proach to discover novel microRNAs that were deregulated in NSCLCs.

156 It is highly deregulated in numerous diseases, including cancer.

157 sduction directs metazoan development and is deregulated in numerous human congenital disorders and c

158 In summary, circulating lncRNAs are deregulated in obesity.

159 We identified miR-155-5p and miR-148a-3p as deregulated in OS.

160 hosphate (S1P) metabolism and signalling was deregulated in OSCC.

161 triptase was congenitally and constitutively deregulated in our prior studies, and therefore it was u

162 utamine metabolism pathways were shown to be deregulated in pancreatic ductal adenocarcinoma (PDAC).

163 tly shown that serum sphingolipids (SLs) are deregulated in patients with chronic liver disease.

164 n all, 607 and 396 miRNAs were significantly deregulated in PDAC and IPMN versus C.

165 demonstrate that S1P receptor expression is deregulated in primary OSCCs and that S1PR2 is over-expr

166 Although Notch signaling is deregulated in prostate cancer, the role of this pathway

167 that the actin nucleator Formin 2 (Fmn2) is deregulated in PTSD and in Alzheimer's disease (AD) pati

168 deregulated in initial tumors was similarly deregulated in recurrent tumors thereby indicating that

169 gulated by genotoxic agents and how they are deregulated in resistant cells.

170 genes, (antisense) long non-coding RNAs are deregulated in skin tissue of systemic sclerosis patient

171 that AMP-activated protein kinase (AMPK) was deregulated in the brain of Alzheimer's disease (AD) pat

172 tem cell fates in other systems and could be deregulated in the context of developmental disorders an

173 tes to aneuploidy and suggest that it may be deregulated in the initiating stages of a broad spectrum

174 the sensitive MCF-7 breast cancer cells and deregulated in the paclitaxel-resistant MCF-7Tax(R) cell

175 Transcription factors (TFs) are commonly deregulated in the pathogenesis of human cancer and are

176 suggests that these genes are significantly deregulated in tumours with MEN2A-like and MEN2B-like mu

177 searched for proteins which are specifically deregulated in UHCA.

178 anscription factor that has been shown to be deregulated in up to 70% of human cancers, can be used a

179 Since the Hippo pathway is deregulated in various cancers, designing inhibitors of

180 e a class of small noncoding RNAs frequently deregulated in various human malignancies, it remains un

181 me activation is essential for host defense, deregulated inflammasome responses and excessive release

182 uring T3SS activation, we isolated secretion-deregulated IpaB mutants using random mutagenesis and a

183 cytokine and immune regulator; however, when deregulated, it leads to several major chronic inflammat

184 Deregulated JAK2 signaling has emerged as the central ph

185 NPM-ALK-deregulated kinase activity drives several pathways that

186 Although deregulated kinase pathways are drivers of malignant pro

187 Depletion of OCT2 or HCF1 deregulated latency transcription and histone modificati

188 g the differentiation process and that, when deregulated, lead to pathogenic events.

189 Deregulated levels of IL-18 are involved in the pathogen

190 mycobacterial survival within macrophages by deregulating lipid droplets via ATG2 repression.

191 Fatty liver was associated with a deregulated liver expression of aminotransferases, which

192 alpha and this may be a novel mechanism that deregulates liver inflammatory signaling.

193 l B cells through the GC reaction and widely deregulated lncRNA expression patterns in HL.

194 The expression patterns of 917 recurrently deregulated lncRNAs are correlated with clinical data in

195 Many recurrently deregulated lncRNAs are enriched in co-expressed cluster

196 adipogenic gene expression by epigenetically deregulating long-range enhancers of the anti-adipogenic

197 y reactions and allergic responses depend on deregulated mast cell activity.

198 avior of cancer and other diseases linked to deregulated membrane signaling states.

199 s a novel mechanism utilized by KSHV LANA to deregulate MHC-II gene expression, which is critical for

200 findings support that most of the identified deregulated microRNAs (miR-21, miR-23b, miR-31, miR-126,

201 Sets of deregulated microRNAs (miRNAs), termed miRNA signatures,

202 egulatory pairs were identified within these deregulated microRNAs and mRNAs, which consisted of 17 u

203 Cs with aPL-IgG or anti-dsDNA-IgG antibodies deregulated microRNAs expression, and decreased miRNA bi

204 148a-3p and miR-155-5p are species-conserved deregulated miRNA in OS.

205 led at the carotid lesion site, identified 8 deregulated miRNAs (miR-15b, miR-29c, miR-30c/d, miR-150

206 t of these mRNAs represent major targets for deregulated miRNAs and might play important roles in the

207 Target prediction for deregulated miRNAs and piRNAs revealed experimentally va

208 Most of the deregulated miRNAs are involved in progression of T1DM.

209 by the validation of the most significantly deregulated miRNAs by RT-qPCR in an independent sample s

210 al analysis of the predicted mRNA targets of deregulated miRNAs identified common modifications betwe

211 We explored deregulated miRNAs in an glomeruloendothelial in vitro m

212 es with respect to C, with a large number of deregulated miRNAs shared by both neoplastic lesions.

213 cancer cell expression data highlights many deregulated miRNAs.

214 array analysis, we identified a total of 26 deregulated miRNAs.

215 ion of a mouse model, we show that H. pylori deregulates mitochondria by two novel mechanisms, both r

216 Deregulated mitochondrial respiration induced by ClpXP t

217 ary epithelial cells increases beta-catenin, deregulates mitosis and stimulates cell proliferation an

218 atients; however, with few exceptions, these deregulated molecular pathways cannot be targeted therap

219 Deregulated MT activity contributes to numerous diseases

220 es, from protein synthesis to autophagy, and deregulated mTOR signaling is implicated in the progress

221 sponses in Gkn2 knockout mice were linked to deregulated mucosal innate immunity and impaired myeloid

222 pithelial-to-mesenchymal transition (EMT) by deregulating multiple EMT pathway genes, in addition to

223 ukemia and, possibly, other tumors driven by deregulated Myb.

224 us to define metabolic functions required by deregulated Myc and demonstrate a critical role for lipi

225 -neuroendocrine lineage heterogeneity, while deregulated MYC expression in KRAS mutant mice increases

226 Lymphomagenesis in the presence of deregulated MYC requires suppression of MYC-driven apopt

227 Deregulated Myc transcriptionally reprograms cell metabo

228 ression of downstream genes and consequently deregulating myelopoiesis.

229 mary tumorigenesis, we next examined whether deregulated NE activity enhances mammary tumor growth.

230 We demonstrate that deregulated necroptosis results in systemic inflammation

231 Our results show deregulated neddylation in clinical fibrosis and both in

232 Deregulated neuroendocrine and neurotransmitter receptor

233 Interestingly, 676 deregulated non-coding genes were detected, 257 of which

234 Deregulated Notch signaling is associated with T-cell Ac

235 of cellular responses (cellular senescence, deregulated nutrient sensing and defects in proteostasis

236 defects in proteostasis, epigenetic changes, deregulated nutrient sensing, and exhaustion of progenit

237 man cells, clinical biopsies or endogenously deregulated oncogenic pathways.

238 Deregulated origin firing also causes fork instability i

239 Replication stress and deregulated origin firing increase the number of HO coll

240 s a key role in DNA damage response, and its deregulated overexpression is associated with genotoxic

241 Data support a mechanism in which PI3K-deregulated p27 binds JAK2, to drive STAT3 activation an

242 This overexpression is the result of deregulated P53/RB/E2F pathway activity and is associate

243 revealed the MYC-ARF-p53 axis as the primary deregulated pathway.

244 ng research, uncovering a number of critical deregulated pathways specific to NMZL tumors.

245 y number aberrations, putative driver genes, deregulated pathways, and potential prognostic markers.

246 acid and xenobiotic metabolism among the top deregulated pathways.

247 potent anti-inflammatory functionality, and deregulated PGRN is associated with rheumatoid arthritis

248 Icsbp expression enhances leukemogenesis by deregulating processes that normally limit granulocyte e

249 associated mutations within THRAP3 result in deregulated processing of THRAP3/BCLAF1-regulated transc

250 population of luminal progenitor cells, and deregulated progesterone signaling has been implicated i

251 cer of hepatocytic differentiation that when deregulated promotes HCC initiation and progression.

252 Deregulated protein and Ca2+ homeostasis underlie synapt

253 Deregulated PU.1 gene expression is linked to dysregulat

254 cluding the ubiquitin-proteasome system with deregulated RB destruction frequently associated with pa

255 mouse prone 8 mice, which are known to have deregulated reactive oxygen species metabolism and accel

256 Deregulated receptor tyrosine kinase (RTK) signaling is

257 into the hepatic artery of rats selectively deregulated redox reactions in tumor tissues by increasi

258 tine and liver tissues in which aberrant and deregulated repair results in severe pathologies.

259 man conditions with amygdala dysfunction and deregulated reward pursuit.

260 study offers insights into the mechanisms of deregulated RTK-induced carcinogenesis and provides the

261 r binding to the transcription factor RUNX1, deregulates RUNX1 activity in hematopoiesis, and induces

262 th prokaryotes and eukaryotes, including how deregulating SCI formation during DNA replication or dis

263 B1 as the critical ETS transcription factors deregulating SDHD expression in the context of highly re

264 activate the inflammatory process, and their deregulated signaling causes devastating diseases manife

265 and potentially therapeutic understanding of deregulated signaling downstream of Shank3 deficiency.

266 ur research focused on the identification of deregulated signaling pathways to point out new targeted

267 multiple tumors had different mutations that deregulated similar pathways.

268 Regulatory element analysis of these deregulated snoRNA genes identified strong enrichment of

269 Deregulated SOX2 alters critical genes implicated in hal

270 We tested the impact of deregulated SOX2 expression in a novel organotypic syste

271 Growth is favored by deregulated stem cell division, which enhances the self-

272 ndria, showed that Mrpl40 haploinsufficiency deregulates STP via impaired calcium extrusion from the

273 g this framework, we recovered significantly deregulated subnetworks that were indeed recognized to b

274 ge of LRRK2 and SYNJ1 pathogenic pathways in deregulating SV trafficking in MB neurons as an underlyi

275 XA1 deregulated ALL, PTPN2 mutations in TLX1 deregulated T-ALL, and PIK3R1/PTEN mutations in TAL1 der

276 in ERBB2IP (ERBB2IP(mut) ) have evidence of deregulated TGF-beta signaling with increased regulatory

277 ranscriptome of Rassf1a(-/-) livers was more deregulated than that of Sav1(+/-) livers, and the trans

278 ange of firearm laws to either strengthen or deregulate the existing main federal gun control law, th

279 These mutations cooperate to deregulate the tight control over gene expression that i

280 Exposure to PM2.5 or PM10 deregulated the ability of the A549 cells to express the

281 tal, remains unclear but this event may have deregulated the expression of HHV-6A or 19q genes or els

282 Reduced levels of aspartate deregulated the malate-aspartate shuttle, which is impor

283 Human cytomegalovirus (HCMV) deregulates the cell cycle by several means, including i

284 Loss of EHD1 also deregulates the ciliary SHH signaling with Ehd1-null emb

285 However, human colon carcinoma often deregulates the Fas signaling pathway to evade host canc

286 Extracellularly, p17 deregulates the function of different cells involved in

287 The reduced acetylation in the esk1 mutant deregulates the position-specific activity of the xylan

288 1A is known to promote cell proliferation by deregulating the activities of E2F family transcription

289 or downstream effector of IL-31 signaling in deregulating the physical skin barrier.

290 field and emerging evidence suggesting that deregulating these pathways might have dramatic conseque

291 for innate immunity against infections, but deregulated TLR signalling contributes to inflammatory d

292 One consequence of this process is deregulated transcription factor (TF) activity.

293 T2A) generate oncogenic fusion proteins with deregulated transcriptional potential.

294 nset, including partial reversal of striatal deregulated transcripts and the prevention of the emerge

295 Thus, deregulated tyrosine kinase driven epigenomic alteration

296 eostatic cytokine and its production becomes deregulated with aging, this may suggest that the capaci

297 sease and mild cognitive impairment (MCI) is deregulated with highly increased or decreased transcrip

298 CC patients, miR-192, -215 and/or -200a were deregulated with microvascular invasion or growth advant

299 Deregulated Wnt signaling and altered lipid metabolism h

300 can cause fetal haemorrhagic hydrocephalus, deregulates Yap in the developing aqueduct.