ライフサイエンスコーパス: derepression

1 sed BCL6 targets were enriched for early cGH derepression.

2 e-dependent BACH1 degradation and rapid Spic derepression.

3 bition of the PI3K/AKT pathway leads to gene derepression.

4 the same biological outcome, transcriptional derepression.

5 mechanisms of transcriptional repression and derepression.

6 y correlate with the level of VirB-dependent derepression.

7 which subsequently leads to transcriptional derepression.

8 d H3K4me2 methylation on HSPC genes and gene derepression.

9 o RcnR in six-coordinate sites, resulting in derepression.

10 ousands of genomic sites and associated gene derepression.

11 he integrity of the separated tail module in derepression.

12 is not accompanied by detectable transposon derepression.

13 Ms is required for efficient transcriptional derepression.

14 may also affect other activities involved in derepression.

15 h gene induction responses often achieved by derepression.

16 epressor to ER membranes and subsequent INO1 derepression.

17 1 neonates because of intestinal UGT1A1 gene derepression.

18 rved Dut motif IV is also implicated in SaPI derepression.

19 harmacodynamics using downstream target gene derepression.

20 ceRNA expression change required to observe derepression.

21 ss of H3K9me3 deposition and transcriptional derepression.

22 t shock promoters, supporting a mechanism of derepression.

23 e ubiquitin-proteasome pathway, resulting in derepression/activation of auxin response genes.

24 pose the physical coupling of activation and derepression activities coordinates transcriptional acti

25 ced at ERVs upon H3.3 deletion, resulting in derepression and dysregulation of adjacent, endogenous g

26 he SaPIbov1 Stl master repressor, leading to derepression and mobilization.

27 omatin, whereby FACT knockdown results in ES derepression and more open chromatin around silent ES pr

28 d mouse primary lymphoma cells leads to RBL2 derepression and RB1 reactivation, which in turn inhibit

29 only the apo form of DutNM1 is active in Stl derepression and that dUTPase activity is not necessary

30 tumor cells), a window of opportunity for L1 derepression arises, and additional restriction mechanis

31 protein stability and identifies proteolytic derepression as highly dynamic in regulating the transcr

32 erase 3B (DNMT3B) are a likely cause of D4Z4 derepression associated with low levels of DUX4 expressi

33 y of Dnmt1 resulted in tumor suppressor gene derepression associated with reduced DNA methylation and

34 anti-silencing factor 1A (ASF1A) allowed for derepression at all cell cycle stages, whereas knockdown

35 referential alkaline-expression results from derepression by depletion of the acid-prevalent PacC(72)

36 ment of dUTP binding and dUTPase activity in derepression by DutNM1.

37 rmore, we demonstrate that tunable levels of derepression can be achieved (up to 95%) by designing as

38 Several defects were observed in the derepression circuit in Neurog2(-/-);Ascl1(-/-) mutants:

39 However, Neurog2 was unable to influence the derepression circuit when misexpressed in late cortical

40 arly cortical progenitors via input into the derepression circuit while also influencing other tempor

41 Derepression coincided with DNA demethylation, dissociat

42 Gene derepression correlates with a decrease in H3K27me3 and

43 nly one, which overlaps with a translational derepression element, is functional in vivo.

44 lete, however, allowing G2/M-specific VSG ES derepression following knockdown of histone H3.

45 deletions of rsmA, rsmE or rsmI caused minor derepression in CfcR translation compared to a DeltarsmI

46 We suggest that TE derepression in interspecific hybrids largely reflects a

47 tes on histone H3 are required for full ARG1 derepression in paf1Delta cells, and the repressive effe

48 ese genes in the absence of iron, as well as derepression in the absence of Fur.

49 had reduced DNA methylation correlated with derepression in the pkl mutant, though for the majority,

50 ehavior is the Hox gene Ultrabithorax, whose derepression in two metameric neurons leads to self-righ

51 nts effectively reversed the transcriptional derepression incurred in the UBR5 and BMI1 KO cells.

52 pomethylation, loss of H3K9me and transposon derepression indicate that S-adenosylmethionine-dependen

53 However, disentangling primary target derepression induced by miRNA inhibition from secondary

54 This argues that the observed ES derepression is a direct consequence of histone chaperon

55 these data suggest that biosynthetic pathway derepression is a general consequence of some antibiotic

56 Somatic DUX4 derepression is caused either by a 1-10 unit repeat-arra

57 The control of NCoR1 function and derepression is linked to IKKbeta function, as validated

58 Derepression is marked by accelerated metabolic and oxid

59 ational change leading to substrate-mediated derepression is primarily caused by a rigid body rotatio

60 formational changes leading to drug-mediated derepression is primarily due to a rigid body rotational

61 The derepression is specific to telomeric ESs, and it coinci

62 odel of hair cell regeneration, we show that derepression is sufficient to induce Atoh1 expression, s

63 omparisons of the structures, we postulate a derepression mechanism for SimR that invokes rigid-body

64 nd BC for liver fibrosis by way of Ppargamma derepression mediated by suppression of canonical Wnt si

65 A derepression mode of cell-fate specification involving t

66 Consistent with p53 derepression, NF90/NF45-depleted HeLa cells displayed el

67 ional and posttranscriptional mechanisms, L1 derepression occurs in developmental and pathologic cont

68 FOXO1 represses DIO2 during fasting and that derepression occurs via nutritional activation of the PI

69 n reducing serotonergic neurotransmission by derepression of 5-HT1A autoreceptors.

70 tif for the ARID5B repressor, which leads to derepression of a potent preadipocyte enhancer and a dou

71 induced lignification can be achieved by the derepression of a set of lignin genes.

72 ndamental link between Nodal signalling, the derepression of a specific class of poised promoters dur

73 of one of the tail subunits SIN4 results in derepression of a subset of genes, including FLR1, by a

74 these changes were attributable, in part, to derepression of ACTA2 transcription.

75 equestration in the cytoplasm and subsequent derepression of AI-2-related genes necessary for quorum

76 r results in degradation of the Aux/IAAs and derepression of ARF-based transcription.

77 s heterochromatin at late origins and causes derepression of associated genes.

78 ns, leading to lower RNAII transcription and derepression of aur transcription.

79 degraded via the 26S proteasome, leading to derepression of auxin response factors (ARFs).

80 rains except that encoding G154D BirA showed derepression of bio operon transcription upon overproduc

81 This is mediated in part by derepression of Bmp4 and the tumor suppressor Rb1, which

82 iron limitation in B. subtilis resulting in derepression of both Fur- and PerR-regulated genes.

83 ific hybrids are characterized by widespread derepression of both maternally and paternally inherited

84 ipt levels of the auxin transporter PIN1 and derepression of bud outgrowth.

85 rimary effusion lymphoma B cells resulted in derepression of C/EBPbeta transcript levels.

86 g a signaling mechanism involving NO-induced derepression of catalytic activity.

87 loss of TCF-1 and LEF-1 unexpectedly caused derepression of CD4 expression in T cells committed to t

88 is phenotype are associated with significant derepression of Cdkn1a (p21), Cdkn1c (P27), Lats1, Lats2

89 retinogenesis, the most dramatic change was derepression of cell-type-specific differentiation progr

90 Compromised cellular identity occurs by derepression of characteristic stomach genes, some of wh

91 creased number of mitotic cardiomyocytes and derepression of Chek1.

92 that is probably secondary to inappropriate derepression of cholesterol biosynthesis.

93 to tetrameric CsoRs mediates transcriptional derepression of copper resistance genes.

94 chondrocyte proliferation is due in part to derepression of cyclin-dependent kinase inhibitors Ink4a

95 in imgi2 is caused by a development-specific derepression of cytokinin signaling that involves cross

96 nto the rot promoter by IS256 results in the derepression of cytotoxin expression and increased virul

97 PK3 plants are dwarfed and display a massive derepression of defense genes associated with spontaneou

98 ouse embryonic stem cells (mESCs) causes the derepression of developmental genes and induction of ear

99 The underlying mechanism is transcriptional derepression of DIO2 through the mTORC2 pathway as defin

100 psis genes, AtMORC1 and AtMORC6, which cause derepression of DNA-methylated genes and TEs but no loss

101 hat in vivo occupancy of Fur correlates with derepression of each operon, and the graded response obs

102 he EGFR promoter, results in transcriptional derepression of EGFR, and increased EGFR pathway output.

103 decreases in H4K20me3 and H3K9me3 levels and derepression of endogenous LTR- and LINE-repetitive DNA

104 Deleting either motif led to the derepression of Esco1-proximal genes and functional unco

105 n has been attributed to the transcriptional derepression of Esrrb, the molecular mechanism mediated

106 Transcriptional derepression of F-box protein 32 (FBXO32) (Atrogin1/MAFb

107 the exoribonuclease Xrn1, to compensate the derepression of FET4.

108 degeneration throughout postnatal life, via derepression of fetal expression of Six1 and its targets

109 of Fgf9, we also tested the possibility that derepression of Fgf9 was responsible for the aspects of

110 any different promoters and is necessary for derepression of FLR1 in sin4Delta cells.

111 Here we show that derepression of FLR1 transcription in sin4Delta cells oc

112 ty, increased protein phosphatase 2A levels, derepression of FoxO3a, and enhanced expression of the p

113 Nevertheless, derepression of frataxin by a histone deacetylase inhibi

114 chanistic model for formaldehyde-sensing and derepression of frmRA(B) expression in numerous bacteria

115 rrest in far1 cln2 cells, along with partial derepression of G1/S genes, which implies a repressor-in

116 es, resulting in reduced DNA methylation and derepression of genes at subtelomeres, e.g. Zscan4.

117 ssociated with impaired SC proliferation and derepression of genes expressed in nonmuscle cell lineag

118 then contributes to heterochromatin loss and derepression of genes involved in immune responses.

119 loop in intestinal epithelial cells lead to derepression of genes involved in intestinal maturation

120 hapX does not affect iron uptake but causes derepression of genes involved in iron-consuming pathway

121 assium channels and amino acid transporters, derepression of genes marked with histone H3 lysine 27 t

122 7-trimethylation, as well as transcriptional derepression of genes on the inactive X that cannot be r

123 omotes histone deacetylation, and attenuates derepression of genes under water stress.

124 t murine Mysm1 participates in transcription derepression of genes, among which are transcription fac

125 glycosylase responsible for transcriptional derepression of gliadins and low-molecular-weight gluten

126 eus Molecule 1 (MOM1) causes transcriptional derepression of heterochromatin independently of changes

127 ASXL1-MT resulted in derepression of homeobox A9 (Hoxa9) and microRNA-125a (m

128 Low EZH2 levels resulted in derepression of HOX genes, and knockdown of HOXB7 and HO

129 MDS-like disease in mice is associated with derepression of Hoxa9 and miR-125a and with Clec5a dysre

130 escape senescence by mechanisms that involve derepression of hTERT expression.

131 wing sarcoma, involving post-transcriptional derepression of IGF signaling by the EWS/Fli1 fusion onc

132 SMRT from cultured human adipocytes promoted derepression of inflammatory transcription and elevation

133 wild-type or Trask-deficient mice revealed a derepression of integrin signaling and an enhancement of

134 in turn inhibit PRC2 expression and trigger derepression of its CASP10, DAP1, HOXA5, and HRK pro-apo

135 liferation and angiogenic tube formation via derepression of its direct target gene angiotensin II ty

136 DNA-binding activity, a mutation that causes derepression of its target genes.

137 mice induces T-ALL by a mechanism involving derepression of its well-known target, Etv4 Importantly,

138 n of the Notch ligand Jag1 in podocytes, and derepression of Jag1 by EZH2 inhibition or knockdown fac

139 ts it does so, at least in part, through the derepression of key actin-regulating proteins.

140 ogical means promoted autophagy flux through derepression of key autophagy effectors (such as ATG5, A

141 pt the epigenetic architecture, resulting in derepression of latent pro-osteogenic and -inflammatory

142 Loss of Dicer leads to derepression of let-7 targets at levels that exceed 10-f

143 wide transcriptome analysis revealed a broad derepression of lipopolysaccharide (LPS)-induced glucoco

144 on of CD36-driven inflammatory signaling and derepression of liver X receptor activity.

145 We present evidence that derepression of LXRs contributes to this paradoxical ant

146 myb118 mutants exhibit an endosperm-specific derepression of maturation-related genes associated with

147 Surprisingly, while derepression of MdrT resulted in hyperstimulation of IFN

148 ked the effects of TGF-beta, suggesting that derepression of MeCP2 after TGF-beta treatment may be re

149 by downregulating miR-30a-3p and subsequent derepression of MeCP2-mediated epigenetic silencing of S

150 intenance of self-renewing cells by inducing derepression of megabase-sized gene domains harboring do

151 /ETS fusion protein function that results in derepression of metastasis-associated gene programs.

152 thway of protein N-glycosylation also causes derepression of miRNA target mRNAs.

153 Selective ablation of Bmi1 elicits a derepression of more posterior Hox genes, leading to a s

154 all six members of this miRNA family causes derepression of multiple cell cycle-promoting proteins,

155 fferentiation, knockout of KDM5A resulted in derepression of multiple genomic loci that are targets o

156 to defects in piRNA biogenesis, resulting in derepression of multiple TE families, gametogenesis defe

157 iber size, impaired muscle regeneration, and derepression of muscle developmental genes.

158 ions in the CAF-I complex caused genome-wide derepression of nascent divergent noncoding transcriptio

159 The derepression of neuronal genes was associated with a los

160 ferentially regulated transcripts, including derepression of non-coding repetitive sequences and thei

161 s by integrating activation of NF-kappaB and derepression of NOTCH/RBPJ in myeloid cells through inhi

162 acyl-chain length to determine the degree of derepression of Opi1 target genes.

163 Notably, the VirB-dependent derepression of ospZ requires the same VirB binding site

164 , but not under anaerobic conditions, led to derepression of P(iscR).

165 s of Pbx causes downregulation of Nkx2-5 and derepression of p15Ink4b in spleen mesenchymal progenito

166 irreversible pre-senescence state, caused by derepression of p16(INK4a) (also called Cdkn2a).

167 ly to be involved in transactivator-mediated derepression of PAI-2 transcription in macrophage-like c

168 t intraspecific crosses are characterized by derepression of paternally inherited TE families that ar

169 phila species sometimes suffer from germline derepression of paternally inherited TE families, caused

170 rmation of the evening complex, resulting in derepression of PIF4/5.

171 ement for CK2 phosphorylation of Maf1 during derepression of pol III transcription.

172 leads to spatial redistribution of PRC2 and derepression of Polycomb responsive genes.

173 activity disrupt Polycomb silencing, causing derepression of Polycomb target genes in cells where the

174 atory elements such as enhancers, leading to derepression of polycomb targets including Cdkn2a.

175 reverses HSC activation by way of epigenetic derepression of Ppargamma involving reductions in MeCP2

176 es suppression of necdin and Wnt, epigenetic derepression of Ppargamma, and morphologic and functiona

177 (PRC2) loss-of-function phenotypes, causing derepression of PRC2 target genes and developmental pert

178 talytically inactive form of BRG1 results in derepression of PRMT7 target DNA repair genes.

179 tion to pyruvate, are herein associated with derepression of QrpR-repressed pdhQ.

180 arison of transcriptomes indicated a partial derepression of quiescence-related transcriptional progr

181 P0-null mutant virus but also to mediate the derepression of quiescent HSV-1 genomes in cell culture.

182 ar wild-type levels, and efficiently induced derepression of quiescent HSV-1 genomes.

183 uctive reactivation from latency and induces derepression of quiescent viral genomes.

184 GIC displacement was mediated by derepression of Rap1gap and subsequent inhibition of RAP

185 The ensuing derepression of rDNA transcription promotes cell prolife

186 n neighboring cells, due at least in part to derepression of reelin transcription in a manner depende

187 This pathway appears to facilitate derepression of repressed Bcl11b target genes as immatur

188 he transcription factor REST) and subsequent derepression of REST-downstream genes GRIA2, NFkappaB2,

189 r, the Zur2:Zn3 form loses Zn(II) leading to derepression of RpsNB(S14*) and FolE2, which allow conti

190 such a context, depletion of Tip60 leads to derepression of satellite transcription, decompaction of

191 Derepression of satellite transcripts correlated with ov

192 d fewer in number, which is coupled with the derepression of select TEs.

193 ingly, we found that Eed inactivation causes derepression of several genes, e.g., Sonic hedgehog (Shh

194 orylated at serine 141 (pS141) that mediates derepression of several immune outputs.

195 cellular proteins that initiate a sequential derepression of several kinetic classes of viral genes.

196 tiple steps of the mevalonate pathway causes derepression of several miRNA target genes, with no disr

197 to anterior forelimb defects resulting from derepression of Shh expression.

198 gfr2 loss-of-function in the ectoderm caused derepression of Shh, revealing a role for FGF in Shh reg

199 no acid deprivation leads to transcriptional derepression of silenced transgenes, including integrate

200 YRP in bloodstream form T. brucei results in derepression of silent variant surface glycoprotein ESs,

201 ssociate SimR from its operators, leading to derepression of simX and export of SD8 from the cell.

202 residues within SloR that cause significant derepression of sloABC promoter activity (P < 0.05) comp

203 D because of increased ligand expression and derepression of SMA mothers against decapentaplegic 2/3

204 bition of Cup9 degradation and consequently, derepression of SOK1 transcription.

205 Derepression of spxA2 in a saiR mutant required SpxA2, i

206 Our findings suggest that epigenetic derepression of stromal PR could be a potential therapeu

207 ervention had little effect on acid-mediated derepression of sweet neuron or feeding responses to eit

208 Decreased PRMT7 expression also resulted in derepression of target DNA repair genes and enhanced cel

209 tment of PKA activator forskolin resulted in derepression of target genes by reducing its interaction

210 progresses normally in rest mutants despite derepression of target genes during embryogenesis.

211 -transcriptional repressors and differential derepression of targets to enhance T(H)17 differentiatio

212 in the nucleus and involving tissue-specific derepression of TCF by Lbx2.

213 Furthermore, the pattern of derepression of TE families in interspecific hybrids can

214 Depletion of TbOrc1 resulted in derepression of telomere-linked silent VSGs in both BF a

215 ll cycle leading to nucleosome depletion and derepression of telomeric VSG ESs.

216 Derepression of testis genes, and inappropriate Phf7 exp

217 m cells without Sxl protein exhibit a global derepression of testis genes, including Phf7, a male ger

218 This occurred through derepression of TGF-beta signaling.

219 ated with the transcriptional and epigenetic derepression of the alpha-cell-determining Arx gene in e

220 In particular, derepression of the AmpC beta-lactamase is a common mech

221 Derepression of the ARG1 gene in paf1Delta cells is acco

222 the E3 ligase Cul3, or of Bcl6, induced the derepression of the Bcl6 target genes Batf (basic leucin

223 The pah1Delta mutation resulted in the derepression of the CHO1-encoded phosphatidylserine synt

224 osphatidate phosphatase also resulted in the derepression of the CKI1-encoded choline kinase (Kennedy

225 spective operator DNAs, which will result in derepression of the corresponding mmpL genes.

226 atin relaxation of the D4Z4 repeat array and derepression of the D4Z4-encoded DUX4 retrogene coding f

227 These changes were accompanied by the derepression of the direct microRNA-155 target PU.1 in c

228 sites as are required for the VirB-dependent derepression of the divergent icsP gene.

229 Derepression of the Dleu2 promoter via inhibition of his

230 CS develop dozens to hundreds of BCCs due to derepression of the downstream G-protein-coupled recepto

231 ated with local chromatin decondensation and derepression of the DUX4 retrogene.

232 inal transcription factor Hnf4alpha leads to derepression of the embryonal proto-oncogene Hmga2 in Nk

233 on, FAS can be upregulated epigenetically by derepression of the FAS promoter using methotrexate, whi

234 of the coagulation factors V and VIII and a derepression of the fibrinolysis with high plasma levels

235 When iron is limiting for growth, derepression of the Fur regulon increases the cellular c

236 prevents adult beta cell replication through derepression of the gene encoding cyclin-dependent kinas

237 m their cognate promoters, thus resulting in derepression of the glycolytic genes to overcome H2O2-st

238 how that PKA inhibition by ARHGAP36 promotes derepression of the Hedgehog signalling pathway, thereby

239 We establish that full derepression of the Hh pathway in ptc1;ptc2 mutants conv

240 reaks their anergic phenotype and results in derepression of the Il2 locus, allowing Tregs to display

241 his variant alters RARG function, leading to derepression of the key ACT genetic determinant Top2b, a

242 vated, like other Ca2+-regulated kinases, by derepression of the kinase domain (KD).

243 In the val1 val2 double mutant, derepression of the LEC1, LEC1-LIKE (L1L), and AFL (LAFL

244 the acquisition of effector function through derepression of the let-7 targets, including Myc and Eom

245 (Pol II)-dependent transcripts produced upon derepression of the loci are derived primarily from one

246 th arrest, through a mechanism involving the derepression of the lysomal protease cathepsin B.

247 e and myofibroblasts and was associated with derepression of the miR-143 target Igfbp5, which impaire

248 Additionally, ZEB1-dependent derepression of the miR-200 and miR-183 target friend of

249 sequently, reduced miRNA processing leads to derepression of the miR-200 target ZEB1, stimulates the

250 n transcription factor Prospero, followed by derepression of the neuroblast factors Deadpan, Asense a

251 d by the respective breakpoints, we observed derepression of the neuronal gene SCN3A and reduced LSD1

252 environmental conditions that stimulate the derepression of the NRT2.1 gene influences resistance to

253 Targeting of SOCS2 by miR-194 resulted in derepression of the oncogenic kinases FLT3 and JAK2, lea

254 ory region and that loss of Dnmt1 results in derepression of the p53 locus.

255 This derepression of the pap_2 operon is abolished following

256 SdiA in the ydiV mutant does not affect the derepression of the pap_2 operon, suggesting that YdiV c

257 fect in tomato was mechanistically linked to derepression of the reaction catalyzed by ADP-glucose py

258 ge from the DNA targets, thus inhibiting the derepression of the regulon.

259 ers was found to correlate with the level of derepression of the reporter genes between the two had6

260 The initial step in mobilization is the derepression of the SaPI by the interaction of a phage p

261 functional preexisting TA complex as well as derepression of the TA operon.

262 Knockdown of TAL1 or LSD1 led to a derepression of the TAL1 target genes in T-cell acute ly

263 and fibroblasts resulted in transcriptional derepression of the testis genes, indicating that they m

264 l for the hfq-negative phenotype were due to derepression of the transcriptional factor RovM.

265 s with ribosomes to facilitate translational derepression of the var2csa coding sequence.

266 n in vivo at biotin concentrations that gave derepression of the wild-type strain and retained suffic

267 methylation of chromatin and transcriptional derepression of these loci.

268 a population of endothelial cells, and that derepression of these programs augments haematopoietic o

269 ing in vivo anti-miR dosing, suggesting that derepression of these targets directly reflects changes

270 Sustained derepression of this inhibitor after birth represents th

271 We also show that derepression of this operon greatly reduces PQS concentr

272 that the absence of RpoS and the consequent derepression of tick-phase genes impart a Stay signal re

273 ins often leads to concerted upregulation or derepression of tick-specific spirochetal antigens in th

274 wn of the noncoding RNAs was associated with derepression of TNF mRNA and diminished binding of LRRFI

275 tors, only sigL inactivation resulted in the derepression of toxin gene expression in the presence of

276 KAP1 suppression of PRC1 binding or for KAP1 derepression of transcription at pluripotency-associated

277 r c-Jun in HeLa cells is sufficient to cause derepression of transcription from the SERPINB2 promoter

278 Derepression of transposons upon Piwi depletion correlat

279 p binding efficiency and resulted in partial derepression of Ume6p-regulated genes.

280 ing the need for VP16 to initiate sequential derepression of viral genes.

281 ycistron inactivation was the consequence of derepression of vitamin D signaling via suppression of C

282 Derepression of wild-type p53 by suppressing its negativ

283 taneous disruption of Tsix and PRC2 leads to derepression of Xist and in turn silencing of the single

284 r lysine at position 36 causes a significant derepression of Xist.

285 ciated from chromatin before transcriptional derepression on DNA damage and oxidative stress.

286 nscriptional repressor, RBPJ, and consequent derepression or activation of associated gene promoters.

287 Strains activated by TagF derepression or stimulated through a previously identifi

288 st, increasing HO-1 expression through siRNA derepression or with nonselective pharmacologic inducers

289 romatin assembly factor 1b (CAF-1b) revealed derepression predominantly in S-phase and G2/M.

290 hat dUTPase activity may be important to the derepression process.

291 f H3K27me2 results in global transcriptional derepression proportionally greatest in silent or weakly

292 onal changes associated with ligand-mediated derepression result primarily from rigid-body rotation o

293 cence response and is mediated by epigenetic derepression through the H3K27-specific demethylase (KDM

294 Consistent with derepression, up to 311 features are observed in antibio

295 In addition, Fur derepression was not sufficient for viability in the abs

296 still able to increase Arf, indicating that derepression was not the sole factor.

297 Derepression was particularly noteworthy in metal ion-bi

298 Among the latter were GRHL3, whose derepression was required for the premature differentiat

299 ear relationship with downstream target gene derepression while providing a substantially higher dyna

300 nce, in flies with low KAY-alpha levels, CLK derepression would partially compensate for increased VR