ライフサイエンスコーパス: derivation

1 nt at an early passage is key for successful derivation.

2 s followed up for 5 years was done for score derivation.

3 s to promote their expression and repress NE derivation.

4 ence for memory precursor NK cells and their derivation.

5 in 10 mg versus placebo) were used for model derivation.

6 mutant cancer models, independent of tissue derivation.

7 t accumulated in the viral genome during its derivation.

8 nt could be improved with rigorous parameter derivation.

9 omated EEG parameters were calculated on two derivations.

10 The study group was divided into a derivation (70%) and a validation (30%) cohort.

11 data registry during 2001-2013 were used for derivation (70%) and validation (30%).

12 We present our approach with an analytical derivation, a numerical demonstration, and an experiment

13 index of the composite score was 0.70 in the derivation and 0.67 in the validation cohort.

14 ns were present in 316 patients (21%) in the derivation and 566 (28%) in the external validation coho

15 The derivation and application of a statistical mechanical m

16 ew the characteristics, regulation, in vitro derivation and in vivo induction of NMps.

17 cipants (mean [SD] age, 66 [15] years in the derivation and internal validation cohorts and 69 [11] y

18 ombined, and a 2:1 random split was used for derivation and internal validation, with the fourth coho

19 Here we demonstrate the efficient derivation and isolation of ENS progenitors from human p

20 The derivation and maintenance of human pluripotent stem cel

21 0.001) and regarding discriminatory power in derivation and pooled cohorts (area under the receiver o

22 in dopaminergic progenitors to improve their derivation and predict dopamine neuron content after eng

23 ptimized culture condition that supports the derivation and propagation of a cell population with mes

24 We demonstrate the efficient derivation and prospective isolation of human oligodendr

25 mation than is commonly assumed, as shown by derivation and simulation of these parameters.

26 the remaining 19,884 patients to compare the derivation and validation clusters.

27 of outcome than driving pressure in both the derivation and validation cohorts (p < 0.0000001).

28 with LT waitlist additions 9 years later in derivation and validation cohorts (R(2) = 0.9).

29 oteins (4137 distinct human gene targets) to derivation and validation cohorts of planned myocardial

30 nducted multivariable regression on separate derivation and validation cohorts to identify clinical d

31 The mean scores in the derivation and validation cohorts were 2.7+/-1.9 and 2.6

32 For the derivation and validation cohorts, 98% of patients infec

33 In the derivation and validation cohorts, acute liver injury wa

34 he curve and the Hosmer-Lemeshow test in the derivation and validation cohorts, and assigned a simpli

35 erse event or death was 7.1% and 7.2% in the derivation and validation cohorts, respectively.

36 he selected model was 0.956 and 0.945 in the derivation and validation cohorts, respectively.

37 .80-0.86) and 0.77 (95% CI 0.71-0.83) in the derivation and validation cohorts, respectively.

38 , with a C-statistic of 0.76 and 0.75 in the derivation and validation cohorts, respectively.

39 In derivation and validation cohorts, we evaluated the nega

40 non-SCD and all-cause mortality in both the derivation and validation cohorts.

41 t therapy duration showed modest accuracy in derivation and validation cohorts.

42 ion was randomly divided in a 2:1 ratio into derivation and validation cohorts.

43 A 3-trajectory model best fit both the derivation and validation data sets.

44 014 were retrospectively randomized 2:1 to a derivation and validation dataset, respectively.

45 , negative predictive values were 92% in the derivation and validation groups, respectively.

46 ve predictive values were 92% and 89% in the derivation and validation groups, respectively.

47 Derivation and validation of a risk index based on point

48 Mortality in the derivation and validation sample was 11% and 8% at 28 da

49 and The CCF cohort was divided randomly into derivation and validation samples, and separate risk sco

50 d good discriminatory accuracy in both model derivation and validation sets (c-statistics for 3-, 5-,

51 t indicated satisfactory performance for the derivation and validation sets (p > 0.20).

52 The derivation and validation sets had the same concordance

53 e similar at 3- and 5-year for patients from derivation and validation sets.

54 clinical events (C statistic = 0.725 for the derivation and validation subsets; 95% CI, 0.705-0.746):

55 Through theoretical derivations and numerical simulations we demonstrated th

56 g mechanism is identified through analytical derivations and numerical simulations.

57 Our derivations and results provide the much needed theoreti

58 volume under the surface was 0.50 +/- 0.019 (derivation) and 0.50 +/- 0.034 (validation) (vs chance p

59 and alignment, normalization and reactivity derivation, and RNA structure prediction in a single use

60 nvolves ethical issues associated with their derivation as well as their current and future uses.

61 of the Belin/Ambrosio enhanced ectasia total derivation (BAD-D) and the inferior-superior value (ISV)

62 al infarction; it had good discrimination in derivation (c-statistic 0.80; 95% confidence interval [C

63 etes mellitus; it had good discrimination in derivation (c-statistic 0.82; 95% CI, 0.80-0.84) and val

64 donor template to hiPSCs, and genotyping and derivation/characterization of gene-manipulated hiPSC cl

65 ORBIT scores for major bleeding in both the derivation cohort (0.68 [95% CI 0.66-0.70] vs 0.61 [0.59

66 levated sweat chloride concentrations in the derivation cohort (100.5 mmol/L [SD 10.9] vs 90.4 mmol/L

67 the validation cohort were compared with the derivation cohort (1995-2005; n = 114).

68 For the derivation cohort (Heart and Soul study), outpatients fr

69 3,687 patients randomly divided (2:1) into a derivation cohort (n = 2,482) and a validation cohort (n

70 A derivation cohort (n = 288; 115 deaths) and validation c

71 The model derivation cohort (n = 633) had a 25% prevalence of mali

72 A derivation cohort (n = 888) and internal test cohort (n

73 in the peripheral vein blood after PMI in a derivation cohort (n=15; P<5.70E-5).

74 e blood after planned myocardial injury in a derivation cohort (n=20; P<1.05E-05, 1-way repeated meas

75 ent was associated with exacerbations in the derivation cohort (odds ratio 3.49 [95% CI 1.18-10.3], p

76 r men and women were 5.79% and 6.08% for the derivation cohort (odds ratio [OR], 1.05; 95% CI, 1.02-1

77 in model was 0.12 (95% CI, 0.08-0.16) in the derivation cohort and 0.08 (95% CI, 0.05-0.10) in the va

78 e curve was 0.71 (95% CI, 0.69-0.74) for the derivation cohort and 0.68 (95% CI, 0.65-0.72) for the v

79 stics of 0.72 and 0.70, respectively, in the derivation cohort and 0.69 and 0.65 in ACCORD.

80 bility estimation of the CRS was 0.73 in the derivation cohort and 0.71 in the validation cohort.

81 5% confidence interval, 0.810-0.935) for the derivation cohort and 0.900 (95% confidence interval, 0.

82 </=1) and were followed up for 1 year in the derivation cohort and 2 years in the validation cohort.

83 ll 30-day readmission rate was 5.89% for the derivation cohort and 5.82% for the validation cohort.

84 eloped in 408 (2.7%) of 9973 patients in the derivation cohort and 62 (2.2%) of 2761 patients in the

85 At 1 year after OGI, 255 eyes (29%) in the derivation cohort and 66 eyes (36%) in the validation co

86 6 ICU admissions were included: 9,204 in the derivation cohort and 7,182 in the validation cohort.

87 37 (50%) of 74 patients in the derivation cohort and 89 (47%) of 190 patients in the va

88 Scores 0-2) had a 3% detachment rate in the derivation cohort and a 0% detachment rate in the valida

89 es 2.5-4.5) had a 29% detachment rate in the derivation cohort and a 35% detachment rate in the valid

90 stress Syndrome Network studies used for the derivation cohort and a distinct study used for validati

91 ores 5-7.5) had a 73% detachment rate in the derivation cohort and an 86% detachment rate in the vali

92 801 patients (31.0%) (n = 510 [30.0%] in the derivation cohort and n = 291 [33.0%] in the validation

93 mance of the novel score was assessed in the derivation cohort and validated in patients treated with

94 ependent risk factors were identified in the derivation cohort and were combined into an overall scor

95 on independently predicted meningitis in the derivation cohort and were tested as a 4-item assessment

96 A derivation cohort from three acute respiratory distress

97 782 (16%) of 4870 patients in the derivation cohort had index myocardial infarction, with

98 50 (68%) patients in the derivation cohort had one or more exacerbations at 1 yea

99 The derivation cohort included 4867 consecutive ED patients

100 The 12-point PPCS risk score model for the derivation cohort included the variables of female sex,

101 Derivation cohort models predicting ischemia and bleedin

102 RHF in the derivation cohort occurred in 433 patients (21.7%) after

103 alysis of diverse explanatory variables in a derivation cohort of 1,916 UDCA-treated participants.

104 validate nomograms for OS and PFS, we used a derivation cohort of 493 patients with OPSCC with known

105 Of the 1,290 derivation cohort patients, 83 patients (6.4%) died in t

106 f MRI and clinical data constructed from the derivation cohort predicted mortality in the validation

107 edicted at hospital presentation by miR-122 (derivation cohort ROC-area under the curve [AUC] 0.97 [9

108 We identified a two-biomarker model in the derivation cohort that predicted mortality (area under t

109 Results: The median age of patients in the derivation cohort was 54 years (interquartile range, 40-

110 Analysis of the derivation cohort was performed in July 2013 and analysi

111 Event rates in the derivation cohort were 27% for 5-year mortality and 27%

112 68518 patients from New York and California (derivation cohort) and 153560 patients from Florida and

113 ork from August 2013 through September 2014 (derivation cohort) and from October 2014 through June 20

114 from a previous prospective clinical trial (derivation cohort) and from The Prince Charles Hospital

115 easured in plasma from 86 patients with IPF (derivation cohort) and in 63 patients with IPF (validati

116 GI that presented between 1999 and 2011 (the derivation cohort) with 184 eyes with OGI that presented

117 h proximal middle cerebral artery occlusion (derivation cohort) with known time of symptom onset.

118 8 518 patients from New York and California (derivation cohort), 151 009 (56.2%) were women and 216 4

119 through December 2013 in Brussels, Belgium (derivation cohort).

120 The model c-index was 0.72 in the derivation cohort, 0.66 in the validation cohort, and 0.

121 natory ability for CV death (c-index 0.81 in derivation cohort, 0.78 in validation cohort), with adeq

122 Among 638 patients in the derivation cohort, 121 (18.9%) had CED.

123 Of 178 patients of the derivation cohort, 147 (82.6%) had CT within 4.5 hours.

124 In the derivation cohort, 6 variables were independently associ

125 From the derivation cohort, 938 samples were analyzed, participan

126 r bleeding of 0.73 (95% CI 0.61-0.85) in the derivation cohort, and 0.70 (0.65-0.74) in the PLATO tri

127 phics and clinical factors were modeled in a derivation cohort, and backward stepwise logistic regres

128 statistic by 0.09 (95% CI, 0.06-0.12) in the derivation cohort, and in the validation cohort, the C s

129 In the derivation cohort, AUC was 0.84 (95% confidence interval

130 In the derivation cohort, C statistics were 0.66 for refit Fram

131 In the derivation cohort, LV ejection fraction </=47%, infarct

132 In the derivation cohort, PERSEVERE-XP had an area under the re

133 In the derivation cohort, the mean 7-day oxygenation index impr

134 In the derivation cohort, we identified 2017 contacts of 715 in

135 In our derivation cohort, we included adults aged 18 years or o

136 were validated in a separate cohort from the derivation cohort.

137 and 65% survived 180 days) (P < .001) in the derivation cohort.

138 ng medical condition was assessed within the derivation cohort.

139 ombotic microangiopathy were included in the derivation cohort.

140 Among DAPT Study patients (derivation cohort; mean age, 61.3 years; women, 25.1%),

141 39.3%] girls) were enrolled (n = 2006 in the derivation cohort; n = 1057 in the validation cohort) an

142 ort) and 2584 of whom (n = 1701 [85%] in the derivation cohort; n = 883 [84%] in the validation cohor

143 composite outcome between the validation and derivation cohorts (22 [18.6%] vs 44 [22.4%]; P = .47).

144 splantation/ventricular assist device in the derivation cohorts and confirmed in the validation cohor

145 95% confidence interval, 0.807-0.845) in the derivation data and a C-statistic of 0.803 (95% confiden

146 s to psychosis (n = 52 of 1001; 5.19% in the derivation data set), indicating the need for transdiagn

147 n ability of current models is acceptable in derivation data sets but most models have not been exter

148 Applied to the derivation dataset (n=350), the AUROC for 30-day surviva

149 ntation, using Cox proportional hazards in a derivation dataset, and tested in initial and recent ext

150 Using the derivation dataset, each predictor associated with an AE

151 manifestly symmetric from the start, and its derivation depends, in its entirety, on the structure of

152 For model derivation, each event time window was matched to a non-

153 etical basis is unclear, and no quantitative derivation exists.

154 iciency, and scalability of traditional iPSC derivation, expansion, and differentiation protocols, bi

155 were computed for each subject and for each derivation for both slow and fast spindles.

156 In the Appendix, I use previous derivations for natural direct effect bounds on the risk

157 nuum mechanics theory, we provide analytical derivations for the design of STO devices.

158 The second route is by direct derivation from a human embryo in 2i with FGF2.

159 and ceasing during human embryonic stem cell derivation from blastocyst outgrowths.

160 Previous models of NC formation suggested derivation from neuralized ectoderm, via meso-ectodermal

161 repair chondrocytes potentially due to their derivation from osteogenic cells in the periosteum.

162 editing, stem cell production, and organoid derivation from stem cells represent a revolution in cel

163 f olivine phenocrysts in HIMU lavas indicate derivation from the partial melting of peridotite, rathe

164 the other stating that they are appendicular derivations from the lateral body wall.

165 NASH resolution occurred in 28% (derivation group) and 27% (validation group).

166 h as single cell "omics" and human stem cell derivation, have now greatly accelerated our ability to

167 l Kirchhoff radiation law derivations, these derivations include diffraction, and so are valid also f

168 Model derivation involved measuring these biomarkers in serum

169 Our derivation is guided by the classical problem of univers

170 transient pluripotent state, and that their derivation is molecularly coupled to iPSC formation mech

171 The development of clinically relevant hiPSC derivation methods from patients and demonstration that

172 The derivation model area under the curve was 0.73, and Hosm

173 We developed a derivation model to determine the relative influence of

174 First, we developed a derivation model to determine the strength of prespecifi

175 We developed a 14-item derivation model to predict violent reoffending and test

176 ed a point for each associated factor in the derivation model, the average predicted versus observed

177 The first group was used for derivation modeling (n = 847; data collected from August

178 of 3,371 patients were randomly grouped into derivation (n = 2,247) and validation (n = 1,124) sets.

179 k using a two-thirds random sample for model derivation (n = 3087) and a one-third sample for testing

180 ervice Foundation Trust were included in the derivation (n = 33820) or external validation (n = 54716

181 um women in Kenya were randomly divided into derivation (n = 654) and validation (n = 650) cohorts.

182 The derivation (n =1 555) and the validation cohorts (n = 77

183 patients (n=2988) were randomly divided into derivation (n=2000) and validation (n=988) cohorts.

184 counters had suspected infection (n = 74,453 derivation; n = 74,454 validation), of whom 6347 (4%) di

185 nto a protein homology model of GAT1 allowed derivation of a common binding mode for this class of in

186 We describe the derivation of a novel CD4-independent variant of pathoge

187 pectrum or bipolar disorder, we describe the derivation of a score based on routinely collected facto

188 The objective of this study was the derivation of a sustainable method to exploit the whole

189 The derivation of accurate rate coefficients for these proce

190 main equation, the model allows a systematic derivation of all transport and equilibrium equations, s

191 n, we first report this novel method for the derivation of alpha from existing field dependent drift

192 owledge of wind direction and allows for the derivation of an ad hoc empirical correction factor to p

193 ps skinfold thickness [which allowed for the derivation of arm muscle area (AMA) and arm fat area (AF

194 Here, we report the derivation of arterial endothelial cells from human plur

195 esolution accurate mass measurement to allow derivation of atomic compositions, leading to the sugges

196 sed MLAA algorithm is promising for accurate derivation of attenuation maps on time-of-flight PET/MR

197 LSI enables derivation of both explicit and implicit associations be

198 cular progenitor populations that enable the derivation of cardiomyocytes and functionally distinct e

199 o automated image analysis pipelines and the derivation of cell cycle profiles with both commercial a

200 Collectively, our approach demonstrates derivation of complex tissues from hiPSCs using a single

201 valuate if this model is appropriate for the derivation of correlates of protection for DENV vaccines

202 Defect equilibria are used in derivation of defect diagrams showing the effect of oxyg

203 range of momentum transfers has allowed the derivation of detailed O-O pair correlation functions.

204 mbryonic stem cell (ESC) differentiation and derivation of devitalized materials as an alternative to

205 Substantial progress has been made in the derivation of disease-relevant human donor cell populati

206 advances in human embryo culture and in the derivation of embryonic-like structures from human pluri

207 sociated with progenitor pool maintenance or derivation of endocrine-committed Neurog3(HI) cells, res

208 opped-flow UV/vis spectrophotometry afforded derivation of equilibrium constants and reaction enthalp

209 proaches to filter solar noise to enable the derivation of forest canopy structure and ground elevati

210 Effective derivation of functional airway organoids from induced p

211 rking and performing in one essential organ, derivation of functional intestinal tissues from human p

212 Here, I simplify the derivation of Grafens key result and extend the analysis

213 (PEI) is used for reduction and simultaneous derivation of graphene oxide (GO) to form a biocompatibl

214 This paper presents the derivation of HO2 from observations of HO2NO2 and NO2 in

215 e insight into the maintenance and potential derivation of HSCs in culture.

216 The in vitro derivation of human germ cells has attracted interest in

217 Here we describe derivation of human induced endodermal progenitor cells

218 The derivation of human inner ear tissue from pluripotent st

219 treamlined platform for the highly efficient derivation of human MNs from ESCs and induced pluripoten

220 To date, derivation of human naive-like pluripotent stem cell lin

221 We report the derivation of human-induced pluripotent stem cells (hiPS

222 Here we report the derivation of induced pluripotent stem cells (iPSCs) fro

223 both ascorbate and RA or retinol promote the derivation of induced pluripotent stem cells synergistic

224 key factor towards the generation and clonal derivation of ISL1(+) vascular intermediates, and demons

225 The derivation of mast-cell and basophil transcriptional sig

226 es that utilize stem cells for the efficient derivation of megakaryocytes and platelets have played a

227 Here we present a Bayesian-based derivation of multiview deconvolution that drastically i

228 nt trends of using ZIFs as templates for the derivation of nanoporous hybrid materials, including car

229 , we show parallel, robust, and reproducible derivation of neuroectoderm, neural crest (NC), cranial

230 ed by a dual origin hypothesis, favoring the derivation of neuroendocrine cells from the neural crest

231 According to previous opinion, the derivation of neurons and glia from the central canal (C

232 Derivation of next generation mice bearing an Fgd5-CreER

233 teritinib in plasma were available to enable derivation of one or more pharmacokinetic variables.

234 a novel and effective synthetic pathway for derivation of phenyl alcohols.

235 Re-derivation of pIgR(-/-) mice in germ-free conditions or

236 for confident structural assignments and the derivation of possible correlations between structure an

237 We demonstrate the derivation of proliferating progeny from differentiated,

238 pproaches offer complementary strategies for derivation of PSCs containing exclusively wild-type mtDN

239 The in vitro derivation of regionally defined human neuron types from

240 criptional reprogramming, allowing efficient derivation of SCNT-derived ESCs using adult Age-related

241 The derivation of second-generation biofuels from non-edible

242 roperty can be captured indefinitely through derivation of self-renewing embryonic stem cells (ESCs),

243 The derivation of somatic motoneurons (MNs) from ES cells (E

244 Motivated by the recent derivation of spin-polarized quasiclassical boundary con

245 Increasingly, HDBR material is enabling the derivation of stem cell lines and contributing towards d

246 we show that a chemical cocktail enables the derivation of stem cells with unique functional and mole

247 ing each step in the permeation event allows derivation of structure-kinetic relationships of permeat

248 f integration with other models, and limited derivation of testable hypotheses.

249 A quantitative derivation of the abundance of ice in these regions indi

250 Here, we present a derivation of the Boltzmann distribution in equilibrium

251 duced by the aberrations, and allows correct derivation of the cellular morphology and molecular diff

252 tform provides a simple stage for systematic derivation of the entire range of ectodermal cell types.

253 s associated with the binding process allows derivation of the free-energy components as well as of t

254 port a phase oscillator model that permitted derivation of the ideal responses of the circadian regul

255 Scale, and pulse rate), and were used in the derivation of the Malawi Adult Meningitis Score (MAMS) n

256 Here, we provide a derivation of the principle that applies to arbitrary co

257 Furthermore, the derivation of the quantitative redox state of each TM in

258 Regarding the mechanism, derivation of the rate law from NMR spectroscopic and ki

259 Derivation of these cell types is a critical step toward

260 Derivation of these formulas motivates an interesting qu

261 parent structural similarity are independent derivations of a common ancestral form, which we call "b

262 egment, are likely generated by evolutionary derivations of compartmentalized ciliogenesis.

263 We then describe our recent work on derivations of Murray-von Neumann algebras.

264 e compared for MDS-UPDRS part III score (and derivations of this) to identify subclinical parkinsonis

265 astids derived from a different phylogenetic derivation, of which some have become intimately connect

266 The PSC patients constituted a derivation panel (recruited 1992-2006 [n = 167]; median

267 rolled 11,477 patients-6,002 patients in the derivation phase and 5,475 patients in the validation ph

268 During the derivation phase, physicians recorded the presence or ab

269 sing 424 subjects previously reported in the derivation phase.

270 cs or modern physics, the review and our own derivations presented here aim to encourage undergraduat

271 The derivation results showed that the M-PSF model is user-f

272 ansfer, consistent with previously published derivation results.

273 alibrated and had good discrimination in the derivation sample (area under the curve: 0.76 for 28-day

274 idation (assigning 37 100 individuals to the derivation sample and 10 226 to the validation sample).

275 ar disorder, we assigned 58 771 (78%) to the derivation sample and 16 387 (22%) to the validation sam

276 The derivation sample consisted of 1852 hospitalizations fro

277 In the derivation sample, 830 (1%) individuals committed a viol

278 was fit to predict death after PCI using the derivation sample, and a simplified risk score was creat

279 inatory ability (c-statistics, >0.70) in the derivation sample.

280 95% confidence interval [CI], 77 to 94%; for derivation samples 35/38 [92%; 95% CI, 79 to 98%]; for v

281 tics, was 85/97 (88%; 95% CI, 79 to 93%; for derivation samples, 43/50 [86%; 95% CI, 73 to 94%]; for

282 Using 50 derivation samples, we determined optimal thresholds for

283 We randomly selected 50% of patients for a derivation set, and a validation set comprised the remai

284 Among 2993 persons in the derivation set, prevalence of advanced neoplasia was 9.4

285 leted two independent prospective studies: a derivation study (MAPP) in eight UK hospitals and a vali

286 neuron development that have led to specific derivation techniques.

287 New features are proposed using 1st derivation that reflects multiphysics spatial and tempor

288 itional sled dogs, possibly of post-colonial derivation, the Alaskan Husky, Malamute and Siberian Hus

289 Unlike the original Kirchhoff radiation law derivations, these derivations include diffraction, and

290 pact of biomaterials on the iPSC field, from derivation to tissue regeneration and modeling.

291 d by expert consensus and selected for model derivation using bootstrap resampling.

292 ficiency of human embryonic stem cell (hESC) derivation using somatic cell nuclear transfer (SCNT) li

293 The average time required for score derivation was 102.6 seconds.

294 t, but quantitative RT-PCR showed that their derivation was not stromal.

295 In the derivation, we combined the Maxwell-Wagner mixing equati

296 Two important derivations will be the translation of this information

297 quid extraction of surface water followed by derivation with dansyl chloride.

298 nalytical protocol, which is based on sterol derivation with the dienolphile PTAD, was found to be re

299 als) was divided into a 60% sample for model derivation, with the remaining 40% used for model valida

300 The human naive ES cell state has eluded derivation without the use of transgenes, and forced exp