ライフサイエンスコーパス: desaturation

1 second H abstraction adjacent to the first (desaturation).

2 s, 36% of which were for clinically relevant desaturation.

3 om stearoyl-CoA desaturase 1 (SCD1)-mediated desaturation.

4 of respiratory events, and degree of oxygen desaturation.

5 ccompanied by moaning, tachypnea, and oxygen desaturation.

6 lity by uncoupling fatty acid synthesis from desaturation.

7 istinct reactions, C5-epimerization and C2/3-desaturation.

8 in the temperature responsiveness of omega-6 desaturation.

9 correlated with severity of nocturnal oxygen desaturation.

10 lglycerol substrate based upon the degree of desaturation.

11 3-OH nor 4-OH retinol was an intermediate in desaturation.

12 one of the 10 controls had sleep-time oxygen desaturation.

13 jor eukaryotic phospholipid and site of acyl desaturation.

14 ng intermittent hypoxia to accentuate oxygen desaturation.

15 ordering of alpha oxidation prior to Delta9 desaturation.

16 ovide substrates for chain elongation and/or desaturation.

17 PD) and resting or exercise-induced moderate desaturation.

18 identified pore-scale event during capillary desaturation.

19 of the amygdala reproduced the apnea and O2 desaturation.

20 oxylation, halogenation, ring formation, and desaturation.

21 ion of the C2-thioether side chain, and C2/3 desaturation.

22 t all three genes participated in fatty acid desaturation.

23 of discharge, and the effect of activity on desaturations.

24 urs of discharge in infants with and without desaturations.

25 One of the 75 infants with desaturations (1%) and 2 of the 43 infants without desat

26 ong the 118 infants, 59 (50%) had at least 3 desaturations, 12 (10%) had desaturation for more than 1

27 Of the 75 infants with desaturations, 18 (24%) had an unscheduled visit for bro

28 s compared with 11 of the 43 infants without desaturation (26%) (difference, -1.6%; 95% CI, -0.15 to

29 Oxygen desaturation (353 patients [5.6%]) and vomiting (328 [5.

30 isplacements (32% vs. 56%; P = 0.01), oxygen desaturations (40% vs. 75%; P < 0.001), required reintub

31 31 plants contain a new allele of fatty acid desaturation 5 (fad5), fad5-2, and are therefore partial

32 rations (1%) and 2 of the 43 infants without desaturations (5%) were hospitalized within 72 hours (di

33 Of the 75 infants who had desaturations, 59 (79%) had desaturation to 80% or less

34 05), aspiration events (7% vs 9%; p = 0.69), desaturation (8% vs 4%; p = 0.27), and hypotension (13%

35 duces membrane thinning, along with specific desaturation activities.

36 elta9-desaturase system to adjust fatty acid desaturation activity accordingly.

37 -Dihydrophenanthrene (DHP) gives the highest desaturation activity, the final products being phenanth

38 allergy experienced apnea attack with strong desaturation after an immediate allergic reaction includ

39 chiolitis experienced recurrent or sustained desaturations after discharge home.

40 actors affecting nurses' response to monitor desaturation alarms in postoperative patients on a gener

41 he level of 16:0 exiting the plastid without desaturation also increased to 21%.

42 ow, similar to those in the literature: 8.6% desaturation and 7.4% esophageal placement during intuba

43 ologic inhibition of SCD1 blocked fatty acid desaturation and also exerted antitumor activity in vitr

44 eaction for the transfer of 18:1 into PC for desaturation and also for the reverse transfer of 18:2 a

45 g halogenation, hydroxylation, ring closure, desaturation and aromatic ring cleavage reactions.

46 a-stat strategy increases jugular vein blood desaturation and cerebral oxygen extraction compared wit

47 idity is known to be regulated by fatty acid desaturation and cholesterol, although some cells, such

48 erapeutic interventions to regulate ceramide desaturation and consequent function.

49 FA) composition and calculated indexes of FA desaturation and de novo synthesis by the mammary gland.

50 way collapse during sleep, leading to oxygen desaturation and disrupted sleep.

51 to exercise cessation on cycling and higher desaturation and dyspnea intensity during the 6MWT.

52 In the 6MWT, desaturation and dyspnea were greater in patients with D

53 Mutant strains with defects in fatty acid desaturation and elongation display altered susceptibili

54 lipidome with significant reductions in both desaturation and elongation of hepatic neutral lipid spe

55 gh shared food sources and common endogenous desaturation and elongation pathways.

56 ore >10) and an apnea-hypopnea index with 3% desaturation and from 5 to 30 events per hour were rando

57 C-H bond activation chemistry of two types, desaturation and hydroxylation, using synthetic manganes

58 progress into non-REM sleep, with continuous desaturation and hypercarbia.

59 P450s in that the predominant oxidation is a desaturation and in that hydroxylation represents only a

60 rases, was bifunctional, and performed a 3,4-desaturation and introduced a C-2 keto group into neuros

61 visitors, chemosensitivity parameters (high desaturation and low ventilatory response to hypoxia at

62 perature shifts by adjusting levels of lipid desaturation and membrane fluidity.

63 de-novo lipogenesis, fatty acid elongation, desaturation and oxidation.

64 a cycles during sleep associated with oxygen desaturation and sleep disruption.

65 ThnG catalyzes sequential desaturation and sulfoxidation of PS-5 (5), giving PS-7

66 Subjects demonstrated a modest oxygen desaturation and tachycardia during the procedure that r

67 important influence on the magnitude of the desaturation and the recovery of PO2 following suctionin

68 NHF is associated with better comfort, fewer desaturations and interface displacements, and a lower r

69 , the frequency of obstructive apnea, oxygen desaturation, and arousal contributes to abnormal BP con

70 hat the three pathways, C3 hydroxylation, C3 desaturation, and C2 hydroxylation/radical rearrangement

71 ociated with ventilatory limitation, greater desaturation, and dyspnea.

72 e amygdala co-occurred with apnea and oxygen desaturation, and electrical stimulation of the amygdala

73 y in the plastid, early stages of synthesis, desaturation, and elongases.

74 eaginous yeast naturally deficient in omega3 desaturation, and soybean.

75 rmed in response to an adverse event, oxygen desaturation, and vomiting.

76 presence of respiratory disturbances, oxygen desaturations, and cortical arousals within a 90-s hazar

77 with a high likelihood of OSA, postoperative desaturations, and pulmonary complications.

78 Strong bases are avoided in this desaturation approach, and the key is to merge soft enol

79 Oxygen desaturations are accompanied by increases in ETCO2, sup

80 st, serial decreases in FVC and increases in desaturation area significantly predicted subsequent mor

81 cs to probe fatty acid metabolism, including desaturation, as a function of oncogene expression and o

82 R, 6.68; 95% CI, 3.83-11.63; P < 0.001), and desaturation at exercise in hypoxia equal to or greater

83 okolow index and T-wave amplitude in V5 with desaturation at exercise.

84 (VO(2)) was depressed and there was systemic desaturation at rest that worsened with exercise.

85 beta-rings in two distinctly different ways: desaturation at the 3,4 position and hydroxylation of th

86 Patients exhibiting oxyhemoglobin desaturations at night showed higher plasma triglyceride

87 The mean duration of desaturation below 90% was 69.2 +/- 65.2 s (47; 6-327).

88 children (0.9%) had brief periods of oxygen desaturation below 95%, none of which required airway in

89 8% had desaturations below 80% and 12.5% had desaturations below 70%.

90 ion, with 31 (10.2%) seizures accompanied by desaturations below 80% and 11 (3.6%) seizures below 70%

91 zures had desaturations below 90%, 31.8% had desaturations below 80% and 12.5% had desaturations belo

92 In these 19 seizures, all oxygen desaturations below 85% were accompanied by an increase

93 Pulse oximetry showed oxygen desaturations below 90% in 101 (33.2%) of all seizures w

94 Desaturations below 90% were significantly correlated wi

95 neralized convulsions, 34.8% of seizures had desaturations below 90%, 31.8% had desaturations below 8

96 scar VT ablation, and avoidance of cerebral desaturations below a threshold of 55% may safely guide

97 nzymes participating in the omega3/6 Delta8 -desaturation biosynthetic pathways for the formation of

98 sure during wakefulness was predicted by the desaturation, body mass, and arousal indices, whereas va

99 affects phosphatidylcholine (PC) fatty acyl desaturation by disturbing the balance between FAD2 and

100 lls, as has been widely shown previously for desaturation by fish and many other organisms.

101 0-CoA into lipids, thereby shielding it from desaturation by Ole1p.

102 augmented the proportion of apneas with O(2) desaturations by 12%.

103 atty acid synthesis, while losing fatty acid desaturation capacity.

104 ecursors through consecutive elongations and desaturations catalyzed, respectively, by fatty acyl elo

105 Whereas overexpression of Ole1p increases desaturation, co-overexpression of Ole1p and Sct1p resul

106 Thus, failure to properly govern FA-Delta9-desaturation contributed to decreased nematode viability

107 We propose that palmitoyl-protein desaturation defines a new mechanism of proteolipid modi

108 r greater detail but typically only catalyze desaturation (dehydrogenation) reactions.

109 mination of the severity and duration of the desaturations, delayed hospitalizations within 72 hours

110 hereas overexpressing fads1, unrelated to LA desaturation, did not.

111 Sleep-time desaturation directly correlated with alveolar-arterial

112 This deficiency in desaturation drives an imbalance between the saturated a

113 .422; p<0.01) and events (rho=0.57; p<0.01), desaturation duration (rho=0.505; p<0.01), and SpO2 (rho

114 ortance of stratifying patients by degree of desaturation during a 6MWT before attributing prognostic

115 t changes in distance walked and quantity of desaturation during a six-minute-walk test (6MWT) would

116 Although noninvasive ventilation reduces desaturation during intubation of severely hypoxemic pat

117 ion in subjects who experience oxyhemoglobin desaturation during physical activity but are not severe

118 The aim of this study was to assess oxygen desaturation during sleep in hepatopulmonary syndrome.

119 upplementation in subjects who show episodic desaturation during sleep that is not attributable to ob

120 Desaturation during the 6MWT was associated with increas

121 nding the quantitative control of fatty acid desaturation during the biosynthesis of seed storage oil

122 ly, 50% of the patients met the criteria for desaturation during the intubation procedure.

123 oup: subcutaneous fat necrosis and transient desaturation during the MRI.

124 d stable COPD with moderate exercise-induced desaturation (during the 6-minute walk test, Spo2 >/=80%

125 nea syndrome without prolonged oxyhemoglobin desaturation, early adenotonsillectomy, as compared with

126 r 10 seconds with no thoracic motion after a desaturation episode.

127 rms) exhibit decreased membrane phospholipid desaturation, especially in phosphatidylcholine.

128 tes), 75 of 118 infants (64%) had at least 1 desaturation event (median continuous duration, 3 minute

129 monitoring hours in 103 patients yielded 342 desaturation events (duration 23.6s [20.99, 26.1]) and 7

130 65% of patients with desaturation events received interventions which correla

131 ications were for clinically relevant oxygen desaturation, facilitating timely nursing response and i

132 mpact on SA, resistance gene-mediated, or FA desaturation (FAD) pathways on ssi2-mediated signaling.

133 Higher proportions of distal elongation and desaturation fatty acid products were seen only in the p

134 results indicate that C-H hydroxylation and desaturation follow analogous stepwise reaction channels

135 e Delta6- and Delta8-pathways, which perform desaturation followed by elongation or elongation follow

136 ) had at least 3 desaturations, 12 (10%) had desaturation for more than 10% of the monitored time, an

137 xD3 and MsexD5 biosynthesize 3UFAs via E/Z14 desaturation from diunsaturated fatty acids produced by

138 Oxygen desaturation greater than 5% from rest to peak exercise

139 Children with and without desaturations had comparable rates of return for care, w

140 Although temperature regulation of desaturation has been studied at the molecular and bioch

141 ly the consequence of reduced membrane lipid desaturation, implicating other mdt-15-regulated process

142 We imaged the process of capillary desaturation in 3D and demonstrated its impacts on the t

143 trimer gallate in particular modified lipid desaturation in C. elegans, revealed by hyperspectral co

144 te modulates lipid deposition and fatty acid desaturation in Caenorhabditis elegans.

145 udies highlight the importance of fatty acid desaturation in cancer growth and provide a novel mechan

146 to link the function of SAD6 with fatty acid desaturation in crown galls, the lipid pattern was analy

147 that heat inhibits both omega-6 and omega-3 desaturation in phosphatidylcholine, leading to a propor

148 pid 16:1n-7 and FA indexes of elongation and desaturation in relation to lipogenesis.

149 esaturates (deoxy-Mb) and the extent of this desaturation in relation to O2 availability provide an e

150 elimination specifically impacts fatty acid desaturation in the endoplasmic reticulum (ER), suggesti

151 ellular metabolism, including for fatty acid desaturation in the endoplasmic reticulum.

152 ssion increased Suc synthesis and fatty acid desaturation in the leaves.

153 m that was not caused by a decrease in lipid desaturation in this extremophile.

154 the terminal reactions, C5 epimerization and desaturation, in simple carbapenem production.

155 Nineteen had SDB (oxygen desaturation index > 5 events/h).

156 Elevated oxygen desaturation index (>/=15 events/hour) and high percenta

157 The serum desaturation index (an indirect measure of SCD) was sign

158 ing moderate-to-severe apnea) and the oxygen desaturation index (ODI; the number of times per hour of

159 ess was only associated with the mean oxygen desaturation index among the polysomnography parameters

160 hemoglobin level of 6.5-8.5%, and an oxygen desaturation index of 15 or more events per hour to posi

161 leic acid (14:1 cis-9) concentration and C14 desaturation index.

162 Nocturnal BP dipping was predicted by the desaturation index.

163 Two desaturation indexes (16:1/16:0 and 18:1/18:0) were used

164 as also observed between obesity and adipose desaturation indexes.

165 supporting the assumption that ictal oxygen desaturation is a consequence of hypoventilation.

166 natal effects are minimal; however, maternal desaturation is a possibility and requires one-to-one su

167 r, the temperature responsiveness of omega-6 desaturation is controlled by a separate QTL on chromoso

168 (SNO-Hb), through which hemoglobin (Hb) O(2) desaturation is coupled to regional increases in blood f

169 et al. (2017) indicate that increased lipid desaturation is essential to stem-like characteristics i

170 g the MAGIC population suggests that omega-6 desaturation is largely controlled by cis-acting sequenc

171 hesis in plants includes a complex series of desaturation/isomerisation reactions, catalyzed by four

172 10% of the monitored time, and 51 (43%) had desaturations lasting 3 or more minutes continuously.

173 shift, arterial constriction and haemoglobin desaturation, lasting at least an hour.

174 rious adverse event in 498 therapy sessions (desaturation less than 80%).

175 Using a cerebral desaturation level of 55% as a lower safety limit to gui

176 and n-3 fatty acids of higher elongation and desaturation levels, which indicated a greater promotion

177 id metabolism that results in elongation and desaturation lipid products is thought to play a role in

178 s were stratified by the presence/absence of desaturation < or = 88% during a baseline 6MWT.

179 g, systolic blood pressure <90 mm Hg, oxygen desaturation <80%, and extubation.

180 m Hg, systolic blood pressure <90 mm Hg, and desaturation <80%.

181 Episodes with desaturations < 90% SpO2 were more common with alfentani

182 th the apnea hypopnea index (AHI) and oxygen desaturation measures.

183 ng reactivity complementary to that of prior desaturation methods.

184 ed to those obtained by the state-of-the-art desaturation methods.

185 er information, such as chain elongation and desaturation, might also be derived through the use of t

186 ting scale), interface displacements, oxygen desaturations, need for ventilator support, and reintuba

187 r, with 18:0-acyl acyl carrier protein (ACP) desaturation occurred at the delta(9) position.

188 Conclusion: Oxygen desaturation occurred during sleep in 70% of hepatopulmo

189 We found that central apnea and O2 desaturation occurred when seizures spread to the amygda

190 44.4%; P < 0.001, but no clinically relevant desaturations occurred.

191 Positional analysis is consistent with ADS desaturation of 16:0 on MGDG.

192 henotypes is not associated with the further desaturation of 18:1 to linoleic or linolenic acids in p

193 ", a biosynthetic process requiring a Delta6 desaturation of 24:5n-3 to 24:6n-3.

194 FAD-dependent enzymes that catalyze the 1,2-desaturation of 3-ketosteroid substrates to initiate deg

195 ith specificity for this acyl group and more desaturation of acyl groups occurring on phosphatidylcho

196 egrees of regioselectivity and yields in the desaturation of alcohols compared to those obtained by t

197 ve visible light-induced Pd-catalyzed remote desaturation of aliphatic alcohols into valuable allylic

198 n in all structures and resulted in profound desaturation of arteries.

199 erse respiratory event was defined as oxygen desaturation of at least 5%, pulmonary aspiration, and n

200 ompanied by marked arterial constriction and desaturation of cortical haemoglobin.

201 kinetics of DHC accumulation, the enzymatic desaturation of DHCs fulfills the criteria of an oxygen

202 Desaturation of dietary alpha-linolenic acid (ALA) to om

203 xpression of SCT1 dramatically decreases the desaturation of fatty acids and affects phospholipid com

204 nd CrFAD6, likely donating electrons for the desaturation of fatty acids that stabilize monogalactosy

205 the genes for the synthesis, elongation, and desaturation of fatty acids that supply the phospholipid

206 r degradation thereby inducing Rsp5-mediated desaturation of fatty acids.

207 ain, protection against oxidative stress, or desaturation of fatty acids.

208 cts upon starvation stress by elongation and desaturation of fatty acyl chains, implying that only th

209 activities were also observed: i.e. Delta15 desaturation of linoleic acid as well as trans-Delta12 a

210 Fatty acid desaturation of membrane lipids is a strategy for plants

211 lytic method is described for the alpha,beta-desaturation of N-protected lactams to their conjugated

212 The desaturation of NMDARs causes a deficit in hippocampal l

213 3 are synthesized in developing seeds by the desaturation of oleic acid (18:1) esterified on the memb

214 he major activity of these genes was Delta12 desaturation of oleic acid, but unusual activities were

215 at the omega-7 pathway proceeds via Delta(9) desaturation of palmitoyl-ACP followed by elongation of

216 This approach allowed for efficient desaturation of readily available silyl ethers into synt

217 These results indicate that the desaturation of saturated fats such as stearate by SCD i

218 -15 control transcription of genes governing desaturation of stearic acid to oleic acid.

219 D activity but instead catalyzed cis-Delta13 desaturation of stearolic acid when expressed in yeast.

220 ta9D) catalyzes the O(2) and 2e(-) dependent desaturation of stearoyl-acyl carrier protein (18:0-ACP)

221 the CNS levels of d-serine, which leads to a desaturation of the coagonist binding site of synaptic a

222 from C4 hydroxylation and Delta4 and Delta8 desaturation of the component long-chain bases (LCBs).

223 Desaturation of the ER membrane may serve as an auxiliar

224 hetic pathway anaerobically, or by oxidative desaturation of the existing fatty acids catalysed by de

225 ne cluster have been associated with reduced desaturation of the precursor polyunsaturated fatty acid

226 re may not be complete Ca(2+) saturation and desaturation of the troponin Ca(2+) regulatory sites wit

227 ocesses as hydroxylations, chlorinations and desaturations of inert, aliphatic C-H bonds.

228 d as well as trans-Delta12 and trans-Delta11 desaturations of stearolic acid (9-octadecynoic acid).

229 hat Ncb5or supplies electrons for fatty acid desaturation, offer new insight into the regulation of a

230 saturase 2 (FADS2) protein to perform Delta6 desaturation on C24 fatty acids in the endoplasmic retic

231 re prescribed 24-hour oxygen, and those with desaturation only during exercise were prescribed oxygen

232 nfusions can improve analgesia, but maternal desaturation or even apnoea is more likely.

233 e oxidation of dihydrophenanthrene by either desaturation or hydroxylation pathways.

234 ect to this plane determines which reaction, desaturation or hydroxylation, will occur.

235 nd the desaturation pathway, with all of the desaturation originating via hydrogen abstraction at C3

236 ts who had stable COPD with moderate resting desaturation (oxyhemoglobin saturation as measured by pu

237 ter to form an alcohol or proceeds along the desaturation pathway via a second H-abstraction to affor

238 om from C-4 (or possibly C-3) initiating the desaturation pathway, followed by a sequential abstracti

239 for both the C-H hydroxylation at C3 and the desaturation pathway, with all of the desaturation origi

240 In an effort to elucidate the lipid desaturation pathways in this model alga, a mutant with

241 ioning of acyl groups between elongation and desaturation pathways.

242 describe the discovery of altered fatty acid desaturation phenotypes associated with mutants of At1g1

243 vulnerability, resulting in saw-tooth oxygen desaturation possibly representing the earliest manifest

244 Hydroxylation and desaturation proceed by means of a short-lived radical t

245 differ from controls in PUFA elongation and desaturation processes.

246 rded C2 (26%) and C3 (43%) hydroxylation and desaturation products (31%).

247 cally reduced amounts of C3 alcohol (8%) and desaturation products (5%), while the radical rearranged

248 Three minor desaturation products are produced, with at least one of

249 erevisiae yields mixtures of cis/transDelta8 desaturation products, predominantly as trans isomers.

250 but this radical apparently does not afford desaturation products.

251 f magnitude decrease in De relative to Do as desaturation progressed down to nanoscale films.

252 s of Arabidopsis result primarily from VLCFA desaturation, rather than by elongation of long chain mo

253 Here we report a desaturation reaction of simple, unactivated alkanes tha

254 th of these rearrangements, as well as a C-4 desaturation reaction, are observed.

255 egioselectivity and stereospecificity of the desaturation reaction.

256 etioplast metabolism by participating in the desaturation reactions of carotenogenesis and in one or

257 n seeds by 85%, the effects on 18:1 and 18:2 desaturation reactions were much less (<25% and <60%, re

258 rallel pathways of fatty-acid elongation and desaturation reactions, which are followed by sequential

259 requiring 11 oxygen molecules and fatty acid desaturation requiring 1 oxygen molecule per double bond

260 owed by elongation or elongation followed by desaturation, respectively.

261 array of reactivities (i.e., hydroxylation, desaturation, ring closure, etc.), they all share a comm

262 The duration of hemoglobin desaturation (Sa(O2) < 90%) correlated with increased in

263 ivation, de novo FA synthesis (ACACA, FASN), desaturation (SCD, FADS1), triacylglycerol synthesis (AG

264 is a logarithmic loss of SNO(RBC) with oxyHb desaturation (slope, 0.043).

265 ect by replacing the activity of PTOX in the desaturation steps of carotenogenesis.

266 ications, such as respiratory depression and desaturation, still occur and their importance cannot be

267 It is proposed that a 3,4-desaturation subsequent to 4-hydroxylation of the beta-r

268 osure with ventilatory equivalent and oxygen desaturation suggests that paraquat may be associated wi

269 limitation, although unpredictable transient desaturation suggests that potential subjects should be

270 l mechanism for the regulation of fatty acid desaturation that is based on competition between Ole1p

271 volumes of brine injection, facilitating the desaturation that leads to decreased trapping relative t

272 OPD and resting or exercise-induced moderate desaturation, the prescription of long-term supplemental

273 ximetry was performed to evaluate a cerebral desaturation threshold to guide the duration of activati

274 tive mechanisms contribute to maintain lipid desaturation through preferential SCD1 regulation and fa

275 During fast simulated VT (300 ms), cerebral desaturation to </=55% occurred in more than half (53%)

276 less for at least 1 minute and 29 (39%) had desaturation to 70% or less for at least 1 minute.

277 infants who had desaturations, 59 (79%) had desaturation to 80% or less for at least 1 minute and 29

278 classical transcript mediates direct Delta4 desaturation to yield 22:6n-3 and 22:5n-6 in human cells

279 nce of fatty acid transformation, especially desaturation, to determination of metabolic fate.

280 verse respiratory events: 58 cases of oxygen desaturation, two pulmonary aspirations, 10 cases of air

281 pathway interactions in modulating membrane desaturation under temperature stress has been suggested

282 e examined whether seizure-associated oxygen desaturation was a consequence of hypoventilation and wh

283 Oxygen desaturation was a late phenomenon.

284 Sleep-time desaturation was correlated with clinical variables.

285 The degree of desaturation was significantly correlated with seizure d

286 ents with COPD experiencing exercise-induced desaturation, we evaluated improvements in exercise tole

287 larger, and post-CSD oligemia and hemoglobin desaturation were more severe in FHM1 brains.

288 lemental-oxygen group, patients with resting desaturation were prescribed 24-hour oxygen, and those w

289 lmitoleic and oleic acids (Delta9 fatty acid desaturation) were decreased in TKO relative to wild typ

290 besity and the magnitude of nocturnal oxygen desaturation, which is an important pathophysiological c

291 nown to up-regulate fatty acid synthesis and desaturation, which is carried out by the oxygen-consumi

292 functionalities to ultimately effect remote desaturation, while leaving behind a synthetically usefu

293 Among the 62 infants with desaturations who had diary information, 48 (77%) experi

294 In vitro assays confirmed delta(4) desaturation with 16:0-ACP; however, with 18:0-acyl acyl

295 ed as clinically relevant (i.e., true oxygen desaturation with SpO2<89 for >15s) or irrelevant (i.e.,

296 ol (MGDG) synthase in yeast conferred Delta7 desaturation, with 16:1Delta7 accumulating specifically

297 atalyzes most, if not all, omega3 fatty acid desaturation within the "prokaryotic pathway" for lipid

298 carbon chain to produce an isolated olefin (desaturation) without overoxidation is one of the most i

299 Thus, it seems likely that delta(4) desaturation would require a non-extended, perhaps U-sha

300 However, delta(4) desaturation would require the accommodation of 12 carbo