ライフサイエンスコーパス: descent

1 ian descent, and 7215 individuals of African descent).

2 d 6435 cannabis-exposed controls of European descent.

3 east cancers in young individuals of African descent.

4 ice the rate seen in populations of European descent.

5 ere predominantly (1296 [92.4%]) of European descent.

6 nantly nonconsanguineous parents of European descent.

7 ffects in 64,421 individuals of non-European descent.

8 e horizontal plane, which simulates vertical descent.

9 romosome and are maintained through vertical descent.

10 eralisability to populations not of European descent.

11 Asian, African American and Mexican American descent.

12 mutagenized BTx623 seeds through single-seed descent.

13 itional results from populations of European descent.

14 to fields that examine and use genealogical descent.

15 ation testing in two populations of European descent.

16 sing eyes of patients of African or European descent.

17 hether the rules we report also share common descent.

18 have a core set of proteins that evolves by descent.

19 severity of NAFLD in individuals of European descent.

20 tify risk loci among individuals of European descent.

21 from two unrelated families of Puerto Rican descent.

22 cancer (CRC) risk in populations of European descent.

23 rth American, of Northern European and Asian descent.

24 in 22,647 AS cases and controls of European descent.

25 Participants were all of European descent.

26 and 12,966 individuals without T2D of Latino descent.

27 amp ascent and descent, and stair ascent and descent.

28 shared structure, function and evolutionary descent.

29 using parts of the genome to be identical by descent.

30 ent and are less concerned with phylogenetic descent.

31 8 collections of Asian, African and European descent.

32 ts and 561 healthy controls, all of Japanese descent.

33 n=1943), Hispanic (n=795), and Asian (n=405) descent.

34 individuals of East Asian, Indian or Iranian descent.

35 randomly selected families of white European descent.

36 ly peak (</= 20 min), followed by a constant descent.

37 rrelations in the states of cells related by descent.

38 airs than on regions not shared identical by descent.

39 of HCV persistence in individuals of African descent.

40 l 11 patients from 8 families of South Asian descent.

41 48 drug-exposed control subjects of European descent.

42 controls from five study groups of European descent.

43 f 6911 cases and 11 814 controls of European descent.

44 e than 11,000 cases and controls of European descent.

45 30-50) in populations of European and Asian descent.

46 independent samples of European and African descent.

47 positive RA cases and 4315 controls of Asian descent.

48 populations were patrilocal with patrilineal descent.

49 normal elderly controls of European American descent.

50 eatic cancer and 14,397 controls of European descent.

51 ung premenopausal women and women of African descent.

52 All individuals were of European descent.

53 by men of Asian (27%) and then African (25%) descent.

54 sociated with HD in populations of Caucasian descent.

55 of 37,930 individuals of European and Asian descent.

56 s of oral clefts in a population of European descent.

57 45 604 controls from predominantly European descent.

58 ering therapies in HD patients of East Asian descent.

59 out, but few have been conducted for Chinese descent.

60 were women, and all were of Southeast Asian descent.

61 in studies in cohorts of primarily European descent.

62 tion to current local climate than by common descent.

63 based on studies in populations of European descent.

64 = .01), we then used 379 subjects of African descent (142 with spontaneous HCV clearance) to fine-map

65 (85.4% vs. 50.6%), and more often of African descent (25.4% vs. 0.5%) than the ROW.

66 as sought in 10,617 participants of European descent, 3811 African-Americans, and 1561 young adults.

67 tate cancer to be highest in men of European descent (49%), followed by men of Asian (27%) and then A

68 related cirrhosis in individuals of European descent (712 cases and 1,426 controls) with subsequent v

69 ed services and the majority were of African descent (76.2%) and male (95.2%).

70 to be women (53.1%) and of Ashkenazi Jewish descent (76.8%) in comparison with individuals who were

71 individuals (63,526 individuals of European descent, 8765 individuals of Asian Indian descent, and 7

72 d that they were homozygous and identical by descent across their genome.

73 xist, specifically between people of African descent (AD) and European descent (ED) in normal ocular

74 taPPA differs between individuals of African descent (AD) and European descent (ED).

75 roximately one-quarter of humans of European descent affects the expression of histo-blood group anti

76 fective disorder to 13q32-34 in the European descent Afrikaner population from South Africa.

77 tia- and stroke-free individuals of European descent, aged >/=45 years.

78 ntosa (RP) patients of Ashkenazi Jewish (AJ) descent, aiming to identify genotype-phenotype correlati

79 Efficient coordinate descent algorithm is used to solve the optimization prob

80 computationally efficient than a coordinate descent algorithm with a local search.

81 ps into the extremely fast cyclic coordinate descent algorithm.

82 ing using empirical estimates of identity-by-descent allele sharing may be useful for studies of comp

83 iate, and we implement a stochastic gradient descent (AMA-SGD) routine for filter learning.

84 ons in 14 genes that were shared identity-by-descent among affected family members.

85 h identifies segments of maximum identity by descent among affected individuals; the other nominates

86 hromosome was identified through identity-by-descent analysis of 3 affected males.

87 puted SNPs in 9,055 participants of European descent and 2,119 African Americans.

88 yses in 4,387 cases and controls of European descent and 302 African American cases and controls, wit

89 48 (73.4%) self-identified as being of Cuban descent and 407 (19.2%) self-identified as being from Ce

90 eyes of 67 subjects (24 patients of African descent and 43 of European descent) from the Diagnostic

91 study with 3716 North Americans of Hispanic descent and 4867 North Americans of European descent, we

92 157 healthy subjects (88 patients of African descent and 69 of European descent) and 73 progressing g

93 light-skinned individuals of mixed European descent and African-Americans.

94 ominantly found among populations of African descent and are associated with THBD gene expression.

95 sease in individuals and families of Acadian descent and broadens the spectrum of the clinical presen

96 ants (84.5% of participants) of West African descent and clinically normal corneas were included.

97 ividuals (1090 eyes) enrolled in the African Descent and Evaluation Study (ADAGES) with a diagnosis o

98 vations in Glaucoma Study (DIGS) and African Descent and Glaucoma Evaluation Study (ADAGES) with at l

99 Participants from the multicenter African Descent and Glaucoma Evaluation Study and Diagnostic Inn

100 nnovations in Glaucoma Study and the African Descent and Glaucoma Evaluation Study were included.

101 nnovations in Glaucoma Study and the African Descent and Glaucoma Evaluation Study.

102 neries was driven by a combination of common descent and horizontal gene transfer.

103 ociated with HD in populations of East Asian descent and in a minority of patients from other ethnic

104 in 0.3% of North Americans of mixed European descent and is associated with T2D, or L1622I, which is

105 cts between 5% and 25% of people of European descent and is the most common inherited disease of conn

106 We recruited 57 women of Asian descent and measured Fe absorption using stable isotopes

107 nesis in patients with cirrhosis of European descent and provide a strong argument for performing fur

108 results suggest a number of switches in both descent and residence patterns as Bantu farming spread,

109 hip patterns and trace the interplay between descent and residence systems.

110 is of magnetic field measurements during the descent and subsequent multiple touchdown of the Rosetta

111 tients of African descent and 69 of European descent) and 73 progressing glaucoma eyes of 67 subjects

112 an descent, 8765 individuals of Asian Indian descent, and 7215 individuals of African descent).

113 0 years, 49% were women, 14% were of African descent, and comorbidities were highly prevalent.

114 tend to cluster among Jews of North African descent, and Machado-Joseph disease is particularly freq

115 Four of the individuals were of Greenlandic descent, and one was North American, of Northern Europea

116 reased cancer risk in individuals of African descent, and our findings highlight the need to assess t

117 C) and 48,312 (for WHR) individuals of Asian descent, and replicated 33 selected SNPs among 3,762 to

118 olving level-ground walking, ramp ascent and descent, and stair ascent and descent.

119 Hutterites, a founder population of European descent, and subsequent imputation revealed 660,238 sing

120 an, Indian or Asian descent, white [European descent], and coloured [of mixed ancestry according to t

121 is not yet known, but individuals of African descent appear vulnerable.

122 her in the subset of individuals of European descent ( approximately 423 000).

123 layan Sherpas, a human population of Tibetan descent, are highly adapted to life in the hypobaric hyp

124 ients and 10,289 controls, all of East Asian descent, as part of The Genetics of AMD in Asians (GAMA)

125 ollow-up SD OCT line scans showed a flat ELM descent at least once at 34 borders (47%), a curved ELM

126 ty among blacks of South or Central American descent, at 16%.

127 highest probability among whites of European descent, at 75%, and the lowest probability among blacks

128 A coordinate descent based iteratively reweighed least squares (IRLS)

129 Here, we describe a framework for gradient descent-based training of excitatory-inhibitory RNNs tha

130 was present and individuals made distinctive descents before sunrise and sunset.

131 ater in Hispanic children of Native American descent (beta=2.3; P=0.004) than in non-Hispanic whites

132 of middle-aged white individuals of European descent, better CVH was associated with lower HF inciden

133 according to age in individuals of European descent, but we did not observe evidence of statisticall

134 nd more often on regions shared identical by descent by affected sibling pairs than on regions not sh

135 individuals and 13,589 controls of European descent by imputing class I and II human leukocyte antig

136 regions was found in this worldwide European-descent cohort and correlated inversely with variation i

137 ute optic neuritis in individuals of African descent compared with individuals of white race/ethnicit

138 ated with IBD risk in only people of African descent demonstrates the importance of studying the gene

139 riately, show which alleles are identical by descent despite the presence of untyped individuals.

140 ,670 unaffected control subjects of European descent, detected 10 regions associated with PsA and 11

141 the fundamental structure of human society: descent determines the inheritance pattern between gener

142 people of African descent (AD) and European descent (ED) in normal ocular health.

143 viduals of African descent (AD) and European descent (ED).

144 uently constructed by following the steepest descent energy minimization trajectories starting from t

145 e genomic random effect, we used identity-by-descent estimates from accurately phased genome-wide dat

146 IOP measurements with individuals of African descent experiencing the highest IOP when compared with

147 ular, the proposed block coordinate gradient descent feature selection method is evaluated on five be

148 from 2 main ethnic groups (Fijians of Indian descent [FID] and Indigenous Fijians [iTaukei]) in Fiji

149 apes of the external limiting membrane (ELM) descent (flat, curved, reflected, and scrolled) at the b

150 nd hospital visitor controls, both of Indian descent, followed by imputation across the genome.

151 provided no support for their claimed Greek descent following Alexander III of Macedon's invasion of

152 We find a common Bantu and Austronesian descent for all Malagasy individuals with a limited pate

153 thm has been developed within the coordinate descent framework where optimization of the regularized

154 AS data from 123 865 individuals of European descent from 46 cohorts in Stage 1 and Metabochip data f

155 ng arrays in up to 182,416 women of European descent from 57 studies, we found robust evidence (P < 5

156 pmental decisions made within their lines of descent from single stem cells.

157 ith incident AF in 3,309 persons of European descent from the Cardiovascular Health Study, a prospect

158 h Initiative (WHI), and a sample of European descent from the UK Biobank.

159 study of African descent, women of European descent from the Women Health Initiative (WHI), and a sa

160 We included 10,884 individuals of European descent from three genetic isolates and three urban coho

161 xpressive vocabulary in toddlers of European descent from up to four studies of the EArly Genetics an

162 tients of African descent and 43 of European descent) from the Diagnostic Innovations in Glaucoma Stu

163 previously discovered in a people of African descent generalized.

164 independent cohorts, three of white European descent (Germany, n = 4,975; the Netherlands, n = 613; a

165 rgical success) was defined as (1) no apical descent greater than one-third into vaginal canal or ant

166 evidence for a multigenerational matrilineal descent group.

167 igher frequency among populations of African descent (>20%) compared with other ethnic groups (<10%).

168 ional twin analysis (5,733 pairs of European descent, h(2)(24-months) = 0.20).

169 mic features that manifest when identical-by-descent haplotypes are inherited from parents.

170 n kidney lesion among individuals of African descent, has largely disappeared in these regions.

171 However, few populations of African descent have been studied to date.

172 dditional case-control data sets of European descent highlighted a region across introns 2-6 as the m

173 genomic regions that are shared identical by descent (IBD) among individuals can yield insight into p

174 n approximately 12-Mbp interval identical by descent (IBD) between the affected individuals on chromo

175 unusually high amount of shared identical-by-descent (IBD) genomic segments between several Siberian

176 erogeneity and a high degree of identical-by-descent (IBD) haplotype sharing in this founder populati

177 Identity-by-descent (IBD) inference is the problem of establishing a

178 s have proposed state-of-the-art Identity-by-descent (IBD) mapping methods to detect IBD segments bet

179 Identity by descent (IBD) refers to a haplotype segment of a chromos

180 orm a large-scale genome-wide inheritance-by-descent (IBD) scan, but accurate assessment of the signi

181 as a novel indexing strategy of Identity-By-Descent (IBD) segments based on clique graphs.

182 equence differences observed in identical-by-descent (IBD) segments together with a reconstructed mod

183 g a hidden Markov model (HMM) of identity-by-descent (IBD) states along the genome.

184 a tool, diCal-IBD, for detecting identity-by-descent (IBD) tracts between pairs of genomic sequences.

185 ples by harnessing long (>4-cM) identical-by-descent (IBD) tracts shared among distantly related indi

186 using inferred long segments of identity by descent (IBD).

187 ork of over 500 million genetic (identity-by-descent, IBD) connections among 770,000 genotyped indivi

188 roportion of the genome that is identical by descent (IBDG) is predicted better by the pedigree inbre

189 nce of TMPRSS2:ERG fusions in men of African descent implies that alternative genomic mechanisms migh

190 rare, damaging mutations shared identity-by-descent in families with BD could be associated with dis

191 2807 patients and 6441 controls of European descent in our two-stage genome-wide association study.

192 rk pigmentation in Africans are identical by descent in South Asian and Australo-Melanesian populatio

193 he deepest lower mantle associated with slab descent in the north and south Pacific.

194 tal brain volumes of individuals of European descent in the United States correlate significantly wit

195 for researchers with individuals of African descent in their study populations.

196 ts to identify individuals of white European descent in UK Biobank in the half of the population with

197 ndividuals (all individuals were of European descent), including child and adult samples (mean age ra

198 0, 2011, to October 2, 2013, were of African descent, including 57 USAAs and 180 FBAAs (76%).

199 es of ovarian cancer in patients of European descent, including 6,179 of high-grade serous (HGS), 2,1

200 eta-analysis (88,383 individuals of European descent, including 7,292 with AF).

201 al data sources from populations of European descent, including type 2 diabetes cases and non-cases,

202 Essential for fetal testis descent, INSL3 has been implicated in testicular and spe

203 hich may have modulated the climate system's descent into the last ice age.

204 horizontal at some depth before resuming its descent into the mantle.

205 to type 2 diabetes of people of south Asian descent is established, but there is little trial-based

206 ng (but not limited to) accelerated gradient descent, its non-Euclidean extension, and accelerated hi

207 atients with familial PD of Ashkenazi Jewish descent likely carry the G2019S mutation in the LRRK2 ge

208 sion loss and blindness in people of African descent living in resource-limited regions.

209 ied the genome-wide diversity of the African-descent Makranis, who reside on the Arabian Sea coast of

210 ng variant correlations included identity-by-descent mapping and the optimal strategy for joint testi

211 acterized genetically by using single-family descent mapping in progenies segregating for the traits.

212 Identity-by-descent mapping using empirical estimates of identity-by

213 METHODS AND Through identity-by-descent mapping, using approximately 400 000 single-nucl

214 ress, and therefore, mammals with testicular descent may be at a greater risk in the event of scrotal

215 tructures, which was optimized by a gradient descent method to generate chromosomal structural models

216 Gradient descent methods such as Levenberg-Marquardt function are

217 cterial serpins incompatible with a vertical descent model.

218 d second-generation healthy women of Mexican descent (n = 53) were randomly assigned in a crossover d

219 i were identified in individuals of European descent near the genes NEURL (rs12415501; relative risk

220 n ecotoxicological studies, here the seventh descent of a zebrafish line, is discussed.

221 In The Descent of Man, Darwin speculated that our capacity for

222 a reproductive mode that assures the clonal descent of progeny; however, a truly clonal bacterial sp

223 ntromeric recombination have occurred during descent of the 2 lineages from their common ancestor.

224 bdominal distension has been associated with descent of the diaphragm and protrusion of the anterior

225 s and in females with CAH, androgens inhibit descent of the sinus ridge.

226 In this population predominantly of European descent, OH was associated with an increase in long-term

227 ic leukemia (ALL) in populations of European descent; only a few loci could be confirmed in Asian pop

228 -range images of the Agilkia site during its descent onto comet 67P/Churyumov-Gerasimenko.

229 Moreover, a block coordinate gradient descent optimization algorithm is proposed for high dime

230 el FP reconstruction method under a gradient descent optimization framework in this paper.

231 +/- 3% increase in EMG score and 12 +/- 2 mm descent; P < .001 vs basal values) and intercostal contr

232 European, South Asian, African, and Hispanic descent (pan-ancestry, approximately 475 000), and the o

233 from a cohort of adult Americans of European descent participating in the Atherosclerosis Risk in Com

234 For individuals of European descent, PGS provided a significant increase in variatio

235 n the largest consortium to date of European-descent population-based studies.

236 rphism at codon 47 in TP53 exists in African-descent populations (P47S, rs1800371; referred to here a

237 t within this region is common among African-descent populations but not among Europeans or Native Am

238 on genetic studies within Mexico, in Mexican-descent populations, and likely in many other population

239 ased risk of asthma in offspring in European descent populations, but has not been studied in Latino

240 In contrast to European descent populations, younger maternal age was associated

241 t has been reported that subjects of African descent present with heart failure at a younger age and

242 rray to genotype 753 individuals of European descent presenting specifically with non-familial, spora

243 ancestor-arise naturally as a consequence of descent processes that result in meaningful distinctions

244 Markov Chains to message passing to gradient descent processes, where the algorithms target the robus

245 Our original Random Coordinate Descent (RCD) loop closure algorithm has been greatly im

246 nd site-matched controls of African-American descent recruited from the population-based African Amer

247 ch both chromosomes were shared identical-by-descent, reducing the search space for causative variant

248 was characterized predominantly by hydraulic descent relative to hydraulic lift.

249 on was only confirmed in subjects of African descent (rs6880859; odds ratio, 2.42; P = .01), we then

250 on in humans is the product of residence and descent rules that promote fraternal interest groups, i.

251 In the European descent samples, we confirmed a previously known locus o

252 67% of any AJ genome with long, identical-by-descent segments.

253 l parameters such as (i) stochastic gradient descent (SGD) and its multiple variations, (ii) structur

254 to estimates based on dizygotic identity-by-descent sharing and distant genetic relatedness.

255 nd efficiently outputs pairwise identical-by-descent sharing data.

256 acted as a pitch control structure reducing descent speed and thus playing a key role in landing.

257 did not demonstrate slower stair climbing or descent speed.

258 centration in 45,889 individuals of European descent (stage 1 discovery) and 17,637 additional indivi

259 nd 17,637 additional individuals of European descent (stage 2 replication), and a transethnic meta-an

260 Full tracking of identity by descent status of alleles within the pedigree is underta

261 and homocysteine concentrations in European-descent subjects.

262 light-skinned individuals of mixed European descent than in African-Americans.

263 tified at 22 loci in populations of European descent, the genetic architecture of QRS duration in non

264 als from independent populations of European descent to examine the mechanism underlying endometriosi

265 enome-wide estimates of pairwise identity by descent to identify families and quickly reconstruct and

266 at uses estimates of genome-wide identity by descent to reconstruct pedigrees consistent with observe

267 smokers and 190,178 nonsmokers (87% European descent) to identify loci influencing BMI and central ad

268 y younger, were more likely to be of African descent, took medications for a shorter time, had a lowe

269 ed in a population sample of Native American descent (top hit rs1611115, P = 4.1 x 10(-15)).

270 Across the phylogeny, a change in descent triggered a switch away from patrifocal kinship,

271 Republic, n = 521), and one of black African descent (United States, n = 1,657), totaling 7,766 subje

272 Haplotypes are coloured based on identity by descent using a novel A* search algorithm and we provide

273 One individual of mixed Hispanic/European descent was found to be compound heterozygous for c.460G

274 actors for breast cancer in women of African descent, we conducted a meta-analysis of two genome-wide

275 Using stochastic gradient descent, we derive how the activity in 'tutor' circuits

276 ian Americans, and in individuals of African descent, we examined the prevalence of the effect allele

277 very sample of 7,478 individuals of European descent, we find 4,068 genome- and metabolome-wide signi

278 ge cohort of healthy individuals of European-descent, we show that the amount of Neanderthal-originat

279 descent and 4867 North Americans of European descent, we show that the associations of rs17849502 (NC

280 iously identified in populations of European descent were enriched for significant SNP associations w

281 14,803 cases and 12,262 controls of European descent were genotyped on the OncoArray and combined wit

282 erogeneity, only centres of largely European descent were included for analysis.

283 Patients of African descent were more likely to have an abnormal 10-2 result

284 ations discovered in populations of European descent were transferable to African Americans when adeq

285 such as penis and preputial size, and testis descent, were greater in Sgta(-/-).

286 weight stability in healthy women of Mexican descent, while having no impact on biomarkers of inflamm

287 lation group (black African, Indian or Asian descent, white [European descent], and coloured [of mixe

288 rily affects individuals of northern Swedish descent who share a single point mutation in the fourth

289 to asymptomatic parents of Italian-American descent, who each presented with atypical RP with system

290 articipants were 2 patients of non-Ashkenazi descent with adult acute onset of neurological signs ini

291 rom a sample of 1761 patients of Han Chinese descent with bipolar I disorder who were recruited by th

292 encing of 107 additional patients of Spanish descent with CRD did not reveal other cases with RAB28 m

293 e similar to that of individuals of European descent with Lynch syndrome.

294 onal traits-is explicitly based on Darwin's "descent with modification," provides students with a rat

295 h of which are transmitted in populations by descent with modification-genes vertically by Mendel's l

296 assessed in 2000 unrelated women of European descent with SLE (588 patients with lupus nephritis and

297 PBC cases and 4,036 controls of Han Chinese descent, with subsequent replication in a separate cohor

298 O3 and that low H2O results from large-scale descent within the tropical troposphere.

299 n Brazilians, the COGENT-BP study of African descent, women of European descent from the Women Health

300 nts whose similarity is indicative of common descent, yet which occur in domains currently not though