ライフサイエンスコーパス: desensitize

1 P2X1 receptor function with a propensity to desensitize.

2 2)-based reporters, but cAMP signals did not desensitize.

3 postsynaptic responses when other receptors desensitize.

4 ns are frequent, and some patients cannot be desensitized.

5 s. liganded, closed vs. open, responsive vs. desensitized.

6 hildren in the oral-immunotherapy group were desensitized.

7 DBPCFC without symptoms and were considered desensitized.

8 Of 138 patients desensitized, 29 (21%) had an immediate and 20 (14%) had

9 ntiplatelet strategy centered on blocking or desensitizing 5-HT2AR to attenuate ADP-mediated alphaIIb

10 from the open (5 seconds) compared with the desensitized (75 seconds) form of the channel.

11 s (Ricinus communis) a novel, allosterically desensitized 910-kD Class-2 PEPC hetero-octameric comple

12 ese results show that oral immunotherapy can desensitize a high proportion of children with egg aller

13 The decision to desensitize a patient must always be made on an individu

14 Such AC inhibition is desensitized after prolonged agonist treatment.

15 ral food challenge and were considered to be desensitized; after 22 months, 75% of children in the or

16 markedly up-regulated in failing hearts and desensitizes against acute beta-AR stimulation.

17 Blocking the actions of HMGB1 appears to "desensitize" aged microglia to an immune challenge, ther

18 cannabinoid agonists downregulated CB1Rs and desensitized agonist-stimulated [(35)S]GTPgammaS binding

19 To desensitize allergic individuals, subcutaneous injection

20 Sublingual immunotherapy also desensitizes allergic patients to foods-2 major studies

21 fundamental molecular actions, which are to desensitize alpha4beta2 nAChRs and induce channel openin

22 eveloping novel and selective compounds that desensitize alpha4beta2 nicotinic acetylcholine receptor

23 -2-95) binds with high affinity and potently desensitizes alpha4beta2 nAChRs.

24 re recently, sazetidine-A, which selectively desensitizes alpha4beta2 nicotinic receptors, was shown

25 sed, blocking (125)I-epibatidine binding and desensitizing alpha4beta2Rs.

26 nction after their postsynaptic counterparts desensitize and suggest that a compartment-specific modi

27 BKV viremia was observed in 20% of the desensitized and 10% of the non-desensitized (P<0.001) g

28 BKV viremia was observed in 20% of the desensitized and 10% of the non-desensitized (P<0.001) g

29 t-bound/open-pore, agonist-bound/closed-pore/desensitized and antagonist-bound/closed states.

30 sophils, or neutrophils had been depleted or desensitized and in mice in which FcgammaRI, FcgammaRIII

31 nel blocker [(3)H]tenocyclidine in the nAChR desensitized and resting states with IC50 values of 2 an

32 ts diagnosed in our clinic as AERD that were desensitized and treated with aspirin 300 mg/day between

33 e beta-adrenergic receptors (betaARs) become desensitized and uncoupled from heterotrimeric G protein

34 aneous nociceptors in the mouse to cold, but desensitizes and partially blocks heterologously express

35 We also found that the LKB1 complex desensitizes and suppresses myofilament function indepen

36 ed that alpha1A-ARs are less phosphorylated, desensitized, and internalized on exposure to the phenet

37 XCL8, these receptors become phosphorylated, desensitized, and internalized.

38 sequently, the receptors are phosphorylated, desensitized, and internalized.

39 om a desensitized state following removal of desensitizing antigen.

40 veral P2X receptors, including those able to desensitize, are permeable not only to NMDG(+) but also

41 othalamic-pituitary-adrenal axis feedback is desensitized (as in the case of chronic stress hormone e

42 to the extent that the channel seems not to desensitize at all for the duration of the agonist appli

43 ed by airway afferent nerve stimulation also desensitized at a much slower rate than cough.

44 d nicotine concentration stimulates and then desensitizes autonomic nAChRs leading to disruptions of

45 ee GRK2, and allows it to phosphorylate (and desensitize) beta2ARs, suggesting that the beneficial ef

46 Initially discovered to desensitize betaAR signaling, beta-arrestins are now app

47 Similarly, AT-1001 desensitized both receptor subtypes in a concentration-d

48 ee conformational states (resting, open, and desensitized) but allows for the modulation of the confo

49 esponses both to dynorphin-A and to orexin-A desensitize, but co-application of dynorphin-A and orexi

50 eptor is exposed to bright light, the rod is desensitized by a process known as bleaching adaptation.

51 a(2+)channel coupling in dorsal root ganglia desensitized by ARM390 and the rate of resensitization w

52 mn at the lumbar 2 (L2) segments, which were desensitized by capsaicin.

53 endothelial transmigration of Th1 cells was desensitized by CXCL9.

54 , indicating that the channels are partially desensitized by extracellular nucleotides.

55 In simple model systems, CB1R is desensitized by GRK phosphorylation at two serine residu

56 AdipoR1 is phosphorylatively modified and desensitized by GRK2 in failing cardiomyocytes, contribu

57 Basophils in whole blood were desensitized by incubation with twofold to 2.5-fold incr

58 responsible for their beneficial actions are desensitized by infection.

59 om rat tail artery and vas deferens are also desensitized by OXY, but not by NE or PE, indicating tha

60 Histamine increase in [Ca(2+)](i) was desensitized by repeated addition of agonist and blocked

61 n release of glutamate, synaptic AMPARs were desensitized by transmitter by >90%.

62 ave altered calcium handling, independent of desensitized calcium-contraction coupling.

63 Lastly, downregulation of FNIPs desensitizes cancer cells to Hsp90 inhibitors, whereas F

64 degradation of endogenous FLS2 may serve to desensitize cells to the same stimulus (homologous desen

65 heightened ATF2 activity also sensitizes or desensitizes cells to ER stress, respectively.

66 Allergen specificity was investigated by desensitizing cells from multi-allergic subjects with gr

67 g (IC50 approximately 0.3 mumol) and acts by desensitizing cells to LPS; it fails to block responses

68 y of the formyl peptide receptor-1 (FPR1) to desensitize chemokine receptors CCR1 and CCR2.

69 Rgs1 reduces macrophage chemotaxis and desensitizes chemokine receptor signalling.

70 d presence of neurotransmitter, the channels desensitize (close).

71 nd a positive allosteric modulator, and in a desensitized/closed state in complex with fluorowilliard

72 ief stimuli from pH 8.0 to 5.0, whereas they desensitize comparatively slowly to prolonged activation

73 nfocal imaging was used to determine whether desensitizing conditions cause a change in agonist-recep

74 Our results show a proposed desensitized conformation of the LBD dimer is a highly p

75 ure of the GLIC-DHA complex in a potentially desensitized conformation.

76 gonist concentrations caused monophasic slow desensitizing currents and internalization of receptors

77 , nondilating P2X7R mutants always generated desensitizing currents.

78 r l-DOPA or cocaine, induced adult-like, non-desensitizing D2-autoreceptor responses, selectively in

79 ted that repeated doses of a TLR7 ligand may desensitize dendritic cells in lymphoid organs, leading

80 to evaluate the relative abilities of three desensitizing dentifrices to provide rapid relief of den

81 mediated rejection [CMR], 38 no rejection in desensitized [DES] and non-DES control groups) for rever

82 the minimum number of shut states, either as desensitized distal states (Jones and Westbrook scheme)

83 Our findings contributed to the theory of a desensitized dopaminergic system in bulimia nervosa.

84 XCL12 and CXCL9 chemotaxis and abolished the desensitizing effect of CXCL9.

85 The desensitizing effect of McTnT1-44 on pCa50 was ablated i

86 ndial glucose homeostasis and 2) the insulin-desensitizing effect of protein ingestion is not due to

87 ular responses to allergens, for example, by desensitizing effector cells, inducing regulatory T and

88 Allergen immunotherapy can desensitize even subjects with potentially lethal allerg

89 2 and KCTD16 homo-oligomers produce strongly desensitizing fast deactivating currents and nondesensit

90 2/KCTD16 hetero-oligomers produce moderately desensitizing fast deactivating K(+) currents, whereas K

91 August 2005 to August 2010, 19 patients were desensitized for ABO-incompatible living donor kidney tr

92 otypes and allograft outcomes among patients desensitized for donor-specific antibody (HLA-incompatib

93 levels was evaluated in 13 patients who were desensitized for incompatible renal transplantation.

94 beta-Arrestins desensitize G protein signaling at DA receptors (D1R and

95 ins that are best known for their ability to desensitize G protein-coupled receptors (GPCRs), but als

96 Although the canonical role of GRKs is to desensitize G protein-coupled receptors via phosphorylat

97 regulated by beta-arrestins, which not only desensitize G-protein signalling but also initiate a G-p

98 Chronic stressor exposure also desensitizes glucocorticoid receptors (GR) and diminishe

99 cteristics and outcomes were compared in the desensitized group (N=187) and the non-desensitized grou

100 cteristics and outcomes were compared in the desensitized group (N=187) and the non-desensitized grou

101 n the desensitized group (N=187) and the non-desensitized group (N=284).

102 n the desensitized group (N=187) and the non-desensitized group (N=284).

103 The desensitized group had more lymphocyte depleting inducti

104 The desensitized group had more lymphocyte depleting inducti

105 The desensitized group had significantly lower baseline leve

106 doxorubicin-induced caspase 3 activation and desensitized HeLa cells to doxorubicin cytotoxicity.

107 elf-administered by smokers are predicted to desensitize high-affinity alpha4beta2 neuronal nicotinic

108 Intriguingly, FANCJ depletion desensitizes hMSH5-deficient cells to CPT-elicited cell

109 reconfigure how Hsp104 subunits collaborate, desensitize Hsp104 to inhibition, obviate any requiremen

110 r, but it was 10 and 30 times more potent to desensitize human alpha3beta4 receptors than rat alpha3b

111 We adapted a clinical protocol to desensitize human blood basophils ex vivo and investigat

112 MP or the phosphatase inhibitor okadaic acid desensitized I(Ca) to hypoxia, while PKA inhibition by H

113 on; (2) PKA activation and CaMKII inhibitors desensitized I(Ca), but not I(Ba), to ZnPP; and (3) hypo

114 been rapidly desensitized with 2.4G2 or mock-desensitized in mice in which monocyte/macrophages, baso

115 ld-type TRPV1 HEK-293 cells but were rapidly desensitized in N604T TRPV1 cells.

116 sified as severe reactors, were successfully desensitized in the outpatient setting.

117 response to nicotine consisting of an acute desensitizing increase in firing frequency followed by a

118 s of food allergen; it has shown promise for desensitizing individuals with peanut, egg, or milk alle

119 2A or 2B CTDs had longer openings and longer desensitized intervals, and the first 100 amino acids of

120 meATP; 10 muM) evoked rapidly activating and desensitizing inward currents (peak 18 +/- 3 pA/pF at -6

121 The 7.6 A structure of a desensitized kainate receptor shows how these changes ac

122 eby IFN-gamma contributes to host defense by desensitizing macrophages to the immunoregulatory effect

123 gest that reduced degranulation responses in desensitized MCs arise from aberrant actin remodeling, p

124 unctional IgE remains on the cell surface of desensitized MCs following DS.

125 tion with FcepsilonRI impede the capacity of desensitized MCs to evoke the calcium response that is e

126 was still capable of transducing signals in desensitized MCs.

127 icone substrates suppresses fibrogenesis and desensitizes mesenchymal stem cells (MSCs) against subse

128 proach with anti-FcepsilonRIalpha mAb safely desensitizes mice to IgE-mediated anaphylaxis by inducin

129 ce was as efficacious as native ovomucoid in desensitizing mice.

130 Overall, blocking HMGB1 "desensitized" microglia in the aged brain, thereby preve

131 However, the Cx26 cKO desensitizes mid-high-frequency DPOAEs and active BM res

132 p.P230S (which is heterozygous with p.R65W) desensitized much faster than wild type receptors and re

133 to agonists, Br-PBTC reactivated short term desensitized nAChRs that have at least two alpha4 subuni

134 required for Br-BPTC to reactivate long term desensitized nAChRs.

135 ch both increases activation and reactivates desensitized nAChRs.

136 trations experienced by smokers are known to desensitize nicotinic acetylcholine receptors (nAChRs),

137 Nicotine activates and/or desensitizes nicotinic acetylcholine receptors (nAChRs)

138 ce and transmits an NK-intrinsic signal that desensitizes NK cell responses globally to acute stimula

139 We also show that below pH 5.0, GLIC desensitizes on a time scale of minutes and infer that t

140 guous information about tilt; by selectively desensitizing one or other of the binocular channels usi

141 ms large-conductance homomeric channels that desensitize only modestly in response to ligand [10].

142 ntation Group: (a) High-risk patients (i.e., desensitized or DSA positive/XM negative) should be moni

143 cine/ivermectin complex adopts a potentially desensitized or partially open state.

144 e inhibitor (SSRI) administration to rodents desensitizes or downregulates raphe 5-hydroxytryptamine

145 TGR5 does not interact with beta-arrestins, desensitize, or traffic to endosomes.

146 h frequencies at a physiological pH that may desensitize other receptors.

147 hile the effects of dynorphin-A and orexin-A desensitize over multiple applications, co-application o

148 s subjects with peanut allergy to be rapidly desensitized over as little as 8 weeks of peanut oral im

149 eiving PPOIT and 7.1% receiving placebo were desensitized (P < .001).

150 n 20% of the desensitized and 10% of the non-desensitized (P<0.001) groups by 2 years posttransplant.

151 n 20% of the desensitized and 10% of the non-desensitized (P<0.001) groups by 2 years posttransplant.

152 The slowly desensitizing P2X2 receptor can be activated by free ATP

153 ATP and MgATP(2-) robustly open the rapidly desensitizing P2X3 subtype.

154 d offer a novel alternative for difficult to desensitize patients.

155 ter a mean follow-up of 334 +/- 82 days, two desensitized patients (18%) received a kidney transplant

156 lants without any desensitization treatment, desensitized patients showed higher class I (99% vs. 80%

157 ant and posttransplant blood samples from 33 desensitized patients who received alemtuzumab induction

158 and potentially more efficacious methods for desensitizing patients to food allergens.

159 peanut allergens in vivo and can be used to desensitize peanut-allergic mice.

160 Venom immunotherapy is efficient to desensitize people suffering from insect sting allergies

161 es of PIN-specific kinases and phosphatases, desensitize PIN1 to cytokinin.

162 Chronic DiC8 treatment failed to desensitize PKCalpha in several cell types and did not a

163 ing was more stable in the resting than in a desensitized pore conformation.

164 the kinase diminishes PI(4,5) abundance and desensitizes precursors to RANK ligand-stimulated differ

165 alysis supports that KCTD12 and -12b evolved desensitizing properties by liberating their H1 domains

166 were expressed in locus coeruleus neurons, a desensitizing protocol induced significant internalizati

167 l opens to conduct cations into the cell but desensitizes rapidly.

168 eviously demonstrated that MBP activates IgE-desensitized rat MC and human lung and cord blood-derive

169 in concert with beta-arrestins, classically desensitize receptor signal transduction, thus preventin

170 blem in receptor gating: how the resting and desensitized receptor states both display closed ion cha

171 KCTD12 and -12b generate desensitizing receptor responses while KCTD8 and -16 gen

172 ses while KCTD8 and -16 generate largely non-desensitizing receptor responses.

173 DKaiR1D forms a rapidly activating and desensitizing receptor that is inhibited by both NMDA an

174 Desensitized receptors are thought to be unable to coupl

175 Mechanistically, stimulation of non-desensitizing receptors evoked prolonged inositol-trisph

176 s mainly signal through high-affinity slowly desensitizing receptors to modulate neurons and perform

177 We analyzed 1-year biopsies from desensitized recipients transplanted between 1999 and 20

178 Throughout the PFC, nicotine strongly desensitized responses to ACh in neurons expressing beta

179 GABA activated slowly desensitizing responses in NG2 cells, which were mimicke

180 suggest that TORC2 is regulated by adaptive, desensitizing responses to stimulatory ligands that are

181 eement, low and high BR levels sensitize and desensitize root response to this adverse condition, res

182 eins originally discovered for their role in desensitizing seven-transmembrane receptor signaling via

183 that the GPCR-arrestin complex initiates non-desensitized signalling at the plasma membrane by coupli

184 d outside of its normal distribution, within desensitized skin and scars.

185 Mature SN DA neurons display prominent, non-desensitizing somatodendritic D2-autoreceptor responses

186 nit helix bundle, photolabeling in the nAChR desensitized state (+agonist) deltaM2-18' and two residu

187 edo nAChRs with higher affinity in the nAChR desensitized state ([(3)H]phencyclidine; IC50 = 4 muM) t

188 nds in the ion channel preferentially in the desensitized state and binds with lower affinity to a si

189 of the kainate receptor GluK2 subtype in its desensitized state by cryo-electron microscopy (cryo-EM)

190 r of the open channel, and recovery from the desensitized state can be controlled independently.

191 Human lung mast cells readily recover from a desensitized state following removal of desensitizing an

192 hances the agonist-induced transition to the desensitized state in the prokaryotic channel GLIC.

193 ing activation, these receptors enter into a desensitized state in which the ion channel shuts even t

194 ssignment to a gating intermediate or a fast-desensitized state is discussed.

195 el, identified by photolabeling in the nAChR desensitized state of amino acids within the M2 helices

196 Weak partial agonists that promote a desensitized state of the alpha7 nicotinic acetylcholine

197 at the low absolute free-energy state is the desensitized state of the intact AMPA receptor.

198 r GluN2B subunit enter into a nonconducting, desensitized state that can impact synaptic responses an

199 and then transition to an ATP-bound closed, desensitized state that requires an agonist-free washout

200 P2X2 receptors were forced into a prolonged desensitized state upon activation by ATP through a mech

201 that for wild-type alpha7 nAChR, the 3-furan desensitized state was relatively stabilized compared wi

202 and LBD domains into the density map of the desensitized state we have derived a structural model fo

203 n (with photolabeling reduced by >90% in the desensitized state); and (iii) at the gamma-alpha interf

204 Without an atomic model for the desensitized state, it is not possible to address a cent

205 es of the receptor, including a model of the desensitized state, showed that barbiturates preferentia

206 In the desensitized state, the LBD undergoes a major rearrangem

207 el 1 resembles a resting state and model 2 a desensitized state, thus providing snapshots of gating t

208 tate and in the previously determined low-pH desensitized state, TM2 is a discontinuous alpha helix i

209 t one electrically intermediate off state, a desensitized state, when ligands remain bound at the lig

210 GSG1L favors the AMPAR desensitized state, where channel closure is facilitated

211 on, indicating that it probably stabilizes a desensitized state.

212 at the base of the pore, representative of a desensitized state.

213 onist dissociation and the transition to the desensitized state.

214 ssed channels, enhances the stability of the desensitized state.

215 reflects rapid recovery of mast cells from a desensitized state.

216 l structure of GLIC does not correspond to a desensitized state.

217 trinsically occurring closed conformation or desensitized state.

218 ndent gating transitions from the resting to desensitized state.

219 sting state, whereas propofol stabilized the desensitized state.

220 that memantine stabilizes a Ca(2+)-dependent desensitized state.

221 th respect to the barrier for entry into the desensitized state.

222 that the crystal structures may represent a desensitized state.

223 on reactions during the lifetime of the late desensitized state.

224 ts suggest stabilization of Ca(2+)-dependent desensitized states as a new strategy for pharmaceutical

225 eases occupancy of GluN1/2A and native NMDAR desensitized states entered after accumulation of intrac

226 Dl) = 229 s, while in chicken ASIC1a the two desensitized states have similar values tau(D) 4.5 s.

227 In both the resting and desensitized states of AMPA and kainate receptor subtype

228 Ketamine binding decreases occupancy of desensitized states of the GluN1/2B NMDAR subtype.

229 consisting of nonconducting, conducting, and desensitized states that are starting to become well cha

230 the large difference in stability of the two desensitized states that makes hASIC1a desensitization m

231 usion system shows that human ASIC1a has two desensitized states with markedly different stabilities.

232 he closed/resting, open/activated and closed/desensitized states, and the mechanism by which conforma

233 ases the duration of bursts and destabilizes desensitized states, resulting in a rapid component of r

234 naive receptors favored a slow transition to desensitized states, whereas occupancy of the third bind

235 nate potency and diminishing the ensemble of desensitized states.

236 lix at similar efficiency in the resting and desensitized states.

237 interface conformation in the closed and the desensitized states.

238 he auxiliary subunit GSG1L in the closed and desensitized states.

239 nformation is nearly identical in closed and desensitized states.

240 ave similar conformations in the resting and desensitized states.

241 distinct from the resting and longest-lived desensitized states.

242 ternary conformation between the resting and desensitized states.

243 n antagonist-bound resting and agonist-bound desensitized states.

244 in addition to naive and sensitized states, desensitized states.

245 s that favor the closed and the ligand-bound desensitized states.

246 e closed state to glutamate-bound active and desensitized states.

247 ree energy difference between the active and desensitized states.

248 from desensitization of hASIC1a revealed two desensitized states: short- and long-lasting with time c

249 Removing the desensitizing stimulus from the media following desensit

250 meters were evaluated for differentiation of desensitized subjects from control subjects.

251 are allowed to decay, mouse rods are stably desensitized; subsequent treatment with exogenous 11-cis

252 rotein-coupled receptor that does not become desensitized, suggesting a target for therapy.

253 t application, presynaptic GABA(B) receptors desensitized, suggesting that resistance to desensitizat

254 refore, we examined the ability of ManLAM to desensitize T cells to other chemoattractants as a poten

255 nsgenic rod bipolar cells were more strongly desensitized than control.

256 ht exposure, control rods were more strongly desensitized than transgenic rods.

257 acellular ATP in the Entpd2-knockout animals desensitize the P2X receptors associated with nerve fibe

258 nce indicates that treatment strategies that desensitize the peripheral and central nervous systems a

259 s of the alpha(1c) subunit of Ca(V)1.2 fully desensitized the Ca(2+) channel to hypoxia.

260 d ROS generation and Deltapsim loss and thus desensitized the cells to OTA-induced apoptosis.

261 Costimulation with CXCL9 desensitized the chemotaxis of Th1 cells toward CXCL12 b

262 r, we observed that short exposure to 35% O2 desensitized the neurons responsible for ambient O2 sens

263 Moreover, SAA1(47-104) desensitized the synergy between intact SAA1alpha and CX

264 of the sGC heme to the ferric (Fe(3+)) state desensitizes the enzyme to NO.

265 opin is a light regulator of phototaxis that desensitizes the eyespot when blue light intensities inc

266 uring the internal dialysis of Cs(+) further desensitizes the photovoltage thereby eliminating its di

267 g thermogenesis, while mutation of this site desensitizes the purine-nucleotide-inhibited state of th

268 sms that include reducing the CNG current by desensitizing the CNG channel via Ca(2+)/calmodulin (CaM

269 ples of fear extinction learning and involve desensitizing the individual to cues that trigger anxiet

270 ) has been used for more than 100 years as a desensitizing therapy for IgE-mediated allergic diseases

271 igen-specific IgE on the MC surface and also desensitize these cells in an antigen-specific manner in

272 ing receptor on NK cells and/or T cells, and desensitize these cells.

273 ogram of inflammatory activation that likely desensitizes these cells to further pro-inflammatory sti

274 The cysteinyl leukotriene type I receptors desensitize through negative feedback by protein kinase

275 Our data indicate that Semapimod desensitizes TLR signaling via its effect on the TLR cha

276 ) of 37 SLIT-treated participants were fully desensitized to 10 g of peanut powder, and all 4 achieve

277 bit temporal adaptation, where the system is desensitized to a sustained input.

278 eme iron, in its oxidized state (Fe(3+)), is desensitized to NO and limits cGMP production needed for

279 ave shown that S-nitrosated GC1 (SNO-GC1) is desensitized to NO stimulation following prolonged NO ex

280 Ovalbumin (OVA)-sensitized mice were desensitized to OVA by means of repeated injections of O

281 ss in BM oral immunotherapy (OIT) and become desensitized to UM as well.

282 ested the hypothesis that capsaicin and heat desensitize TRPV1 through distinct mechanisms involving

283 es, whereas ectopic expression of mutant p53 desensitizes, tumor cells to arsenic treatment.

284 lation followed by beta-arrestin recruitment desensitized U50,488H-induced ERK1/2 response.

285 or-specific antibody positive, PRA>80%) were desensitized using IVIG and rituximab.

286 Candidate patients were desensitized using the new RCUH rapid desensitization pr

287 way (PD-1?FoxO1?PD-1) that functions to both desensitize virus-specific CTLs to antigen and support t

288 Thus, the same receptors that desensitize when expressed in the postsynaptic compartme

289 Moreover, we found that loss of ERalpha desensitizes, whereas ectopic expression of ERalpha sens

290 ronic SSRI treatment, 5-HT(1A) autoreceptors desensitize, which allows 5-HT tone elevation.

291 f interneurons in LII-III and LVI completely desensitized, while cholinergic responses in LV interneu

292 were evaluated in mice that had been rapidly desensitized with 2.4G2 or mock-desensitized in mice in

293 inical outcomes of ABO-incompatible patients desensitized with a nonantigen-specific IA device and ri

294 One male recipient who was desensitized with antigen-specific IA died 44 months aft

295 ho are nonreactive to baked milk (BM) can be desensitized with BM to promote tolerance to unheated mi

296 Basophils from multi-allergic subjects were desensitized with grass allergen.

297 Patients desensitized with I+R who remain ABMR have long-term gra

298 Twenty highly sensitized patients desensitized with IVIG+rituximab+/-plasma exchange were

299 Mice were desensitized with serially increasing doses of anti-IgE

300 receptors induced postsynaptic currents that desensitized within minutes, whereas inhibition of presy