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2 t risk of nephrotoxicity the algorithms were designed to achieve target attainment rates of >80% for
8 phase II/III randomized, double-blind trial designed to assess efficacy and safety of nintedanib plu
9 ucted 75 in-field uncontrolled cooking tests designed to assess emissions and efficiency of the Gyapa
10 the development of sequencing methodologies designed to assess genome-wide polyadenylation events.
12 roach, we conducted four large-scale studies designed to assess people's conceptions of mental life m
13 edict bias magnitude; nor did three measures designed to assess possible asymmetries in the distribut
14 ed recollection and recognition memory tests designed to assess recollection and familiarity for the
15 review of the cumulative evidence from RCTs designed to assess the effect of omega-3 polyunsaturated
17 and analyzed a direct observation checklist designed to assess the extent to which patients and fami
19 countries (New Zealand and China), and were designed to assess type of control strain, diet, presenc
22 ional SMS (Substrate Modification Study) was designed to assess whether prophylactic ablation of the
25 eficient (Cu/In + Ga = 0.76) CIGS films were designed to avoid the rather dangerous KCN treatment ste
27 ent [60]fullerene derivative (C60-serPF) was designed to be an amphiphilic nanostructure, which is ab
28 covalently through peptide linkers that are designed to be cleaved by intracellular macrophage prote
29 donepezil-based "bio-oxidizable" prodrugs 1 designed to be converted into dual binding site AChEIs 2
31 lent organic framework (sp(2)c-COF) that was designed to be fully pi-conjugated and constructed from
35 te 13 different amine-containing side chains designed to bind in the minor groove of DNA while spanni
36 uentially administered, modified immunogens (designed to bind progressively more mature bnAb precurso
37 y that a pyrrole-imidazole (Py-Im) polyamide designed to bind the consensus androgen response element
39 s might be susceptible to therapeutic agents designed to block the regulatory pathways in T cells, su
40 dro-4-thiopyranone 13, which were rationally designed to boost the rate of enzyme inactivation by low
43 y guided hearing aid (VGHA) under conditions designed to capture some aspects of "real-world" communi
44 formed using DNA origami approaches and are designed to change conformations in response to a bindin
46 ith two different thermal desorption inlets, designed to characterize the gas and aerosol composition
47 -(pivaloyloxy)alkoxy-carbonyl prodrugs of 14 designed to circulate inert in plasma and be taken up an
48 provides a valuable basis for future studies designed to clarify the therapeutic value of CP blockade
49 , there have been many meta-analysis methods designed to combine gene expression data across many tis
50 ecause aztreonam inhibits AmpCs, a study was designed to compare ESBL detection by the CLSI disk test
51 No published study has been specifically designed to compare medication administration errors bet
52 iple, independent data sources.The study was designed to compare relevant data published by the Food
53 e ART (Arterial Revascularization Trial) was designed to compare survival after bilateral internal th
54 wide mRNA profiling methodology specifically designed to complement high-throughput screening assays.
58 Au nanoparticles/graphene-chitosan has been designed to construct an impedimetric immunosensor for a
59 luorescent probes for signal generation were designed to consume products of the catalytic reaction i
63 thyl DEE, di-n-butyl DBE) were strategically designed to copolymerize with a norbornene-functionalize
64 We then evaluated 5 alternative approaches designed to correct for nonresponse bias under different
66 mmonly contain multiple redundant mechanisms designed to counteract loss or perturbation of a single
67 parental allergens, the hybrid molecule was designed to cover relevant epitopes and evaluated in sil
68 s, all trimeric and monomeric Env immunogens designed to date have failed to elicit such antibodies.
72 sands of nanoparticle formulations have been designed to deliver nucleic acids, most nanoparticles ha
73 Thus, the downstream purification process is designed to demonstrate robust removal of these impuriti
79 djust for confounders and therefore were not designed to determine if earlier or immediate treatment
80 lation study of pralatrexate plus romidepsin designed to determine the dose-limiting toxicities (DLTs
84 tional magnetic resonance imaging tasks were designed to differentiate between activation related to
85 oligonucleotide chains has been specifically designed to direct each AuNP to a distinct location of t
86 time in many species, few studies have been designed to directly compare process-level differences i
88 Labor market and real-life studies were not designed to discriminate between evolutionary and taste-
91 either gaze-contingent music reward therapy, designed to divert patients' gaze toward neutral stimuli
93 ther words, first and second approaches were designed to employ nanomaterials while third and fourth
94 n highlight features of the Pharos interface designed to enable intuitive access to the IDG knowledge
95 we present two computational tools that are designed to enable rapid and high-throughput analyses of
96 alently cross-linked CarHC hydrogel was also designed to encapsulate and release bulky globular prote
98 To evaluate a multisite HIV testing program designed to encourage localized HIV testing programs foc
100 initiative being implemented across 76 ICUs designed to engage strategically the ABCDEF bundle throu
102 thnic Diversity in the Oncology Workforce is designed to enhance existing programs and create new opp
108 reatment) was a multicenter randomized trial designed to estimate the effect of DA before DCB to faci
109 A case-control study of 40 patients was designed to evaluate 1) the differences in biomarkers of
111 ized, placebo-controlled trials specifically designed to evaluate statin therapy in patients with can
113 erage with LCSs/mo) enrolled in a 2-wk trial designed to evaluate the effects of LCSs on the gut micr
115 ter for Medicare & Medicaid Services program designed to evaluate the Million Hearts Cardiovascular R
117 Here, a predictive modeling framework was designed to evaluate the roles of transport limitations
118 ND HIV Vaccine Trials Network (HVTN) 104 was designed to evaluate the safety and tolerability of mult
124 of inductor-capacitor transmission lines is designed to experimentally realize the transformation me
125 ase, are the first clinically approved drugs designed to exploit synthetic lethality, a genetic conce
128 to test whether a pharmacological challenge designed to facilitate dopaminergic transmission can enh
129 ing, gene filtering, and normalization steps designed to facilitate downstream analysis of large, het
133 a peripherally restricted opioid formulation designed to forego central and intestinal side effects.
134 Safe Surgery 2015 South Carolina program was designed to foster state-wide engagement of hospitals in
136 y bioresorbable coronary scaffolds have been designed to function transiently to prevent acute recoil
138 as a straightforward alternative to methods designed to generate contrast in BF imaging for quantita
140 orrelated in a predictive mathematical model designed to guide prognosis on the basis of clinical fea
141 However, existing computational methods designed to handle specific technologies do not scale we
142 multivariable sensors, a sensing material is designed to have diverse responses to different gases an
147 re exists a plethora of in silico algorithms designed to help identify and prioritize SNVs across the
148 ble, versatile and easy-to-use web interface designed to help in prioritizing variants and predicting
150 can also be selectively increased using ASOs designed to hybridize to other translation inhibitory el
151 simple, user-friendly Shiny web application designed to identify differentially expressed genes acro
152 les on gene regulatory regions, they are not designed to identify individual regulatory regions media
153 ly developed for certain enzymes, HTS assays designed to identify ligands that block protein binding
156 Here, we describe a small molecule screen designed to identify regulators of let-7 targets in huma
158 driven by a conventional electronic circuit designed to illustrate the complete integration of silic
159 nique opportunity to assess whether upgrades designed to improve effluent quality could also remediat
160 cable community-based screening intervention designed to improve glaucoma and other eye disease detec
161 zyme serine hydroxymethyltransferase (SHMT), designed to improve microsomal metabolic stability and t
162 ctegravir, a novel, potent, once-daily INSTI designed to improve on existing INSTI options with the b
166 t pneumococcal conjugate vaccine (PCV13) was designed to include disease-causing serotypes that are i
172 r results show that the efficacy of vaccines designed to induce protective T cell responses can be po
174 l small-molecule pan-RAS ligands, which were designed to interact with adjacent sites on the surface
175 demonstrate that a small molecule inhibitor, designed to interfere with CBFbeta binding to RUNX prote
176 Here, we investigated whether a strategy designed to interfere with the cell death-facilitating p
177 iant systems of sensors, circuits and radios designed to intimately interface with the soft tissues o
179 ly, an array of magnetic induction coils are designed to investigate the feasibility of a tomographic
182 rdilysin (dNrd1) in a forward genetic screen designed to isolate genes whose loss causes neurodegener
184 We argue that human-like machines should be designed to make decisions in transparent and comprehens
186 described "Oligonucleotide Retrieval Assay" designed to measure DNA excision repair that is capable
187 that the primary objective of the trial was designed to measure efficacy and not haemolysis in relat
190 ional modification or formulation and can be designed to mediate sequence-specific cleavage of differ
192 QuPath is new bioimage analysis software designed to meet the growing need for a user-friendly, e
194 BP-G) to target the "G site", and (2) an ABP designed to mimic a substrate molecule and have "H site"
196 ing antifogging mechanism in model materials designed to mimic natural systems, and explain the impor
197 ged an offline "feed frame table," which was designed to mimic the full process from a NIR measuremen
200 Microfluidic and CFD circulation models were designed to mimic tumor progression by escalating flow c
202 sly been highlighted and statistical methods designed to minimize such biases have not been implement
205 xamination of synthetic analogues rationally designed to not only overcome vancomycin resistance but
206 ircuits, where particular circuits/chips are designed to optimally perform particular functionalities
208 e harnessed for initiating reaction cascades designed to overcome the stereoelectronic restrictions o
212 present a user-friendly R package, modSaRa, designed to perform copy number variants identification.
215 at, even though synthetic network models are designed to present structural properties similar to tho
216 s challenge, an array of computational tools designed to prioritize and predict the function of nonco
217 ifferent ZnTPP-PDI monomer reference systems designed to probe electron transfer to each of the indiv
218 l gatherings led by trained facilitators and designed to promote healthy behaviours mainly related to
220 aim of the Minamata Convention, a UN treaty designed to protect human health and the environment fro
222 tal technologies refer to electronic systems designed to provide a service remotely and include heter
223 publicly available web application has been designed to provide all Tox21-ToxCast dose-likelihood pr
225 We evaluated a novel pediatric exoskeleton designed to provide appropriately-timed extensor torque
226 Subsequent to binding pocket modifications designed to provide dual d-Ala-d-Ala/d-Ala-d-Lac binding
228 d a custom-made RDE/RRDE working station was designed to provide unique means by which to in situ rea
230 , Pan et al. show that a combination therapy designed to reactivate the p53 tumor suppressor while an
231 that a Temperature Suitability Index (TSI), designed to reclassify climate data relative to optimal
234 fered ART using a streamlined delivery model designed to reduce structural barriers, improve patient-
235 ustification for stronger policy initiatives designed to reduce tanning bed use among young women.
238 for developing pharmaceutical interventions designed to relieve ER stress or modulate the UPR during
244 opment of novel therapeutics: These would be designed to reverse lymphatic dysfunction, either primar
245 y-induced, bendable smart clothing have been designed to reversibly adapt their thermal insulation fu
246 uality metrics into an interactive dashboard designed to richly summarize individual sequencing runs.
248 opportunities for ontogeny-based immunogens designed to select for rare V2-bNAb precursors, and driv
249 weight and hydrophilicity, this conjugate is designed to selectively release morphine in injured tiss
250 llections of DNA sequences can be rationally designed to self-assemble into predictable three-dimensi
251 3-Ala-Val-NHCH2-C identical withCH, which is designed to self-assemble through intermolecular hydroge
252 , unpleasant, and neutral olfactory stimuli, designed to separate distinct phases of reward processin
253 ased on a modified Michelson interferometer, designed to serve as a middle-ear microphone for totally
254 tive Citation Ratio (RCR), a metric that was designed to serve in that capacity, measures the influen
256 as determined in 2 L recirculating mesocosms designed to simulate conditions in Abraham's Creek in Qu
257 Innovative capture of "healthy" controls designed to simulate donor selection processes has ident
261 ual-biosensor based on microelectrode arrays designed to simultaneously monitor lactate and glucose f
263 is reduced, while the I-TASSER-MR server is designed to solve the phase problem for proteins that la
264 effectively complement orthogonal therapies designed to stimulate antiviral immunity, such as therap
266 opment of fSTREAM, a set of analytic methods designed to streamline the analysis of surgically excise
268 and d(XC5XGiX) (X = A, T or none; i < 5) are designed to study the impact of G-repeats on the formati
269 e/endonuclease to a heterochromatin protein, designed to suppress transposon expression and recombina
270 Withania somnifera and the present study is designed to systemically investigate the anti-HCC effica
271 ory community and health system intervention designed to tackle disrespect and abuse by changing the
275 ials have investigated the effects of agents designed to target distinct levels of the IL23 and Th17
276 wing number of examples of chemical entities designed to target exotoxin virulence factors from impor
278 study using F/R incorporated into liposomes, designed to target inflamed endothelium, shows reduced a
280 the amino-terminus of the transposase enzyme designed to target the hypoxanthine phosphoribosyltransf
281 uce TG2-dependent signalling, and that drugs designed to target this site may be potent anti-cancer a
288 We used a logistic random-effects model designed to test within-person and between-persons diffe
289 embling the clonotypes, most of them are not designed to track and examine the dynamic nature of the
293 odel predicts, therefore, that interventions designed to unjam the endosome carry high therapeutic pr
295 uch complexity requires single-cell analyses designed to unravel the interplay of aging dynamics and
298 ovative web application that is specifically designed to visualize and interactively explore intra-mo
300 rameters obtained from a best-fit procedure, designed to yield simulated tumors as close as possible
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