ライフサイエンスコーパス: desired

1 nanomaterials wherein immune stimulation is desired.

2 ile minimizing the intrinsic error rate, are desired.

3 antiarrhythmic drugs are ineffective or not desired.

4 of a targeted GEM delivery system is highly desired.

5 ased response in areas of weak absorption is desired.

6 issue-specific delivery of gRNAs and Cas9 is desired.

7 structures and high sensitivity, are highly desired.

8 ly expand functional Tregs in vivo is highly desired.

9 l charge transfer characteristics are highly desired.

10 ly when directed gene-gene relationships are desired.

11 th humoral and cellular immune responses are desired.

12 measurements of biomechanical properties is desired.

13 te that mimics the pancreatic environment is desired.

14 ialists in the ICU is broadly acceptable and desired.

15 ent transcription from preexisting mRNAs are desired.

16 kpoint therapies in myelogenous leukemia are desired.

17 c health risks from air pollution are highly desired.

18 ts for improved protein solubility is highly desired.

19 s during the photopolymerization reaction is desired.

20 ed if predicting DOC or DO concentrations is desired.

21 lable data handling and analysis solution is desired.

22 cohols and diorganyl diselenides to give the desired 2-organoselenyl-naphthalenes in good yields with

23 e fluorination reaction allows access to the desired 3'-fluoro-3'-deoxytetrose moiety.

24 these parts are chemically etched to produce desired 3D shapes.

25 6-homologation extending the d-hexose to the desired 6-deoxy-d-heptose.

26 gn of tile systems that robustly exhibit the desired abstract behavior in realistic physical models a

27 ng-up space structures are utilized to build desired acoustic gradient metasurface, and the all-angle

28 pro-drug approach was critical to obtain the desired activity in vivo.

29 an intracellular selection process toward a desired activity; and (iii) the characterization of the

30 rinciple of exercise training to promote the desired adaptations for maximising athletic performance.

31 amines were subsequently transformed to the desired allenes under CdI2 or ZnI2 catalysis.

32 The existence of HO-H besides the desired allylO-H end group functionalities was confirmed

33 C(sp(3) )-H bond activation to generate the desired amidated products is reported.

34 correct position, and all eyes achieved the desired anatomic result.

35 rphology and unique edge structure is highly desired and important for fundamental research and poten

36 eir activities, features that facilitate the desired anti-parasitic growth inhibitory effects could b

37 rm, which maintains structural integrity and desired antigenicity.

38 o play a large part in the suitability for a desired application.

39 re different and need to be suitable for the desired applications.

40 operties of TAPP-based materials for certain desired applications.

41 choosing particular components according to desired applications.

42 ithographic printing to form a scaffold with desired architectures.

43 control and can be trapped kinetically when desired are key to creating complex systems that can mim

44 ensuing reductive elimination furnishes the desired arylated product.

45 was used to realize the objective, which was desired as a catalyst to significantly accelerate the de

46 eutic and transmission-blocking activity are desired as high-value partners for combination therapies

47 dual blockade of TGF-beta1 and TNF-alpha is desired as its therapeutic approach.

48 neous and directed assembly is to encode the desired assembly information to building blocks in a pro

49 terials of required mechanical strength with desired balance between stiffness and plasticity.

50 rug-drug interaction concerns to deliver the desired balance of preclinical in vitro properties.

51 imensional materials even in cases where the desired bandgap engineering has been achieved.

52 ficient of hygroscopic expansion to target a desired behavior such as multimodal locomotion.

53 tinct reasons for a failure to engage in the desired behavior.

54 establish the neural patterns that produce a desired behavioral outcome.

55 perties can be tuned in order to exhibit the desired behaviour at the selected wavelength region.

56 lowed by a very successful conversion to the desired beta-d-ido-configuration found in the target hep

57 compound 57 had a superior oral exposure and desired bioavailability of 45% after oral administration

58 e chances for finding binding molecules with desired biological properties; however, achieving drug-l

59 These pathways converge to the desired biosynthetic end product via the (SAM-dependent)

60 The reactions delivered desired bridged benzobicycloheptanone products with exce

61 ctivation energy and selectively producing a desired but kinetically unfavourable product for the imp

62 nd whole grain bread, qualities increasingly desired by consumers in this segment.

63 Disclosure of amyloid imaging results is desired by many cognitively impaired subjects and seems

64 ately, none of these strategies provided the desired C16-epimeric trans-decalin.

65 lted in the stereoselective synthesis of the desired C2-symmetric gem-difluoromethylenated angular tr

66 alogue (20:1), this is functionalized to the desired C21 alpha,omega-diester building block with a li

67 ily converted a dipeptide precursor into the desired C6-functionalized azabicycloalkane scaffolds.

68 w multipotent progenitor cells commit to the desired cell fate.

69 However, generation of desired cell types using this approach is often plagued

70 nt stem cells (iPSC) can be used to generate desired cell types, including naive immune effectors, fo

71 olecules are highly attractive for eliciting desired cellular responses and for understanding biologi

72 the two metals that give the particles their desired characteristics.

73 f conformal catalytic materials that promote desired chemical transformations, while also maintaining

74 new assembled inorganic suprastructures with desired chiroptical response for wide-ranging functional

75 ins to allow chemical-induced proximity of a desired chromatin regulator.

76 azlactones and AlCl3 in toluene produced the desired cis-3-aminochroman-2-ones in 65-90% yields under

77 If pharmacologic treatment is desired, clinicians and patients should select nonsteroi

78 Screening for desired clones with CRISPR-mediated genomic edits in a l

79 program depends on the ability to bring the desired combinations of alleles on chromosomes.

80 Managing desired components of discharge variance will lead to gr

81 of continuous flow leads to isolation of the desired compounds in enhanced yields relative to standar

82 cture search allow precise identification of desired compounds or functional groups.

83 materials, after mesylation, allowed for the desired compounds to be obtained in good yields under mi

84 rther be deposited onto any surface and form desired conductive patterns, potentially applicable to t

85 as a suitable leaving group to generate the desired conjugated lactam.

86 t to the previously reported approaches, the desired conjugates were constructed stepwise using solid

87 lso highlighting the need to explicitly link desired conservation objectives and biodiversity metrics

88 ification and dehumidification, offering the desired control of the moisture level at room temperatur

89 stimethate that would be needed to achieve a desired Css,avg and creatinine clearance.

90 r determining the FeTot required to effect a desired %Cvn is presented.

91 transition-metal catalyst rather than to the desired directing group.

92 o steer supramolecular polymerization in the desired direction (i.e., pathway selection).

93 tors, followed by their magnetization in any desired direction.

94 to generate rotational shear stresses in any desired direction.

95 soft, cubic lattices along predetermined or desired directions, and even imparting a prescribed patt

96 through a number of mechanisms creating the desired dislocations homogeneously distributed within th

97 ly of customized chromatin with specifically desired DNA sequences, core histones, and other chromoso

98 mechanisms accompanying the transition from desired drug effects to adverse events following adminis

99 to continue using cocaine for reasons beyond desired drug-related effects.

100 o, we identified a set of compounds with the desired dual inhibitory activity and enhanced antiprolif

101 tive gain, causing the network to follow the desired dynamics.

102 e DSB by synthetic donor DNAs containing the desired edits, but HDR has been reported to be variably

103 s first-line therapies (prioritized based on desired effect), IV calcium (1D), high-dose insulin ther

104 wall stability by bulk strengthening was the desired effect, then vitrification represents an Iron Ag

105 Testosterone has several desired effects as well as undesired and unknown effects

106 The desired effects include increased facial and body hair,

107 gonally by light and protonation and produce desired electrical output at room temperature.

108 tructure design principles for obtaining the desired electrochemical performance.

109 bility of cell components in the presence of desired electrochemical reaction products is clearly pro

110 omponents are then integrated to produce the desired electronic circuitry by using an empty nozzle (i

111 The desired enantiomer of the final allylic amine can be syn

112 lyst surface and the targeted synthesis of a desired enantiomer requires the implantation of chiral i

113 may thereby accelerate progress towards the desired endpoint (e.g., elimination) or increase the cha

114 ep reconfigures the monolayer to promote the desired environmental interactions.

115 give greater selectivities and rates for the desired epoxidation pathway and present smaller enthalpi

116 re more frequent dosing in order to maintain desired exposures and avoid unnecessarily high peak conc

117 of the test statistics was simulated for the desired false positive control to avoid excess false pos

118 spatial positions and reprogrammable in any desired fashion, with fast response time and high effici

119 m of designing a flow sculpting device for a desired fluid flow shape remains a challenge.

120 ial that matches the refractive index of the desired fluid.

121 ogical properties of cross-linked starch for desired food applications.

122 i) either had to determine the location of a desired food item or a property of a non-food item (leng

123 while, low-damping metallic ferromagnets are desired for charge-based spintronic devices.

124 nhance the mature character of NK cells most desired for effective cancer immunotherapy.

125 cted cells to exceedingly low concentrations desired for HIV-1 remission strategies.

126 nal composite materials are currently highly desired for sustainable energy applications.

127 ased non-precious metal materials are highly desired for the cathodic oxygen reduction reaction (ORR)

128 layed fluorescence (TADF) emitters is highly desired for the practical application of these materials

129 chloric acid (12 N) in methanol afforded the desired free amino acids in 80-88% yields.

130 ectric medium that is scalable to a range of desired frequencies.

131 d by tuning the qubit frequency to bring the desired frequency-conversion transitions on or off reson

132 indings must be stable enough to promote the desired function even in the crowded and fluctuating cel

133 ding, just a mathematical description of the desired function.

134 ation of a given fiber network to optimize a desired function.

135 with a gene drive allele engineered to have desired functionalities.

136 he Dha is installed, the introduction of the desired functionality is limited only by the requirement

137 etic modification would not only produce the desired functionality, it would also help to exfoliate t

138 eptor displaced the reaction in favor of the desired galactofuranosyl containing disaccharide.

139 and time required in generating models with desired genetic modifications.

140 tion of the Diels-Alder adducts provides the desired geometrically defined bis-acenes.

141 research and clinical purposes, is a highly desired goal in patients with acute and chronic pulmonar

142 e monomers confirmed that they packed in the desired head-to-tail orientation and within a viable dis

143 ng steering signals by comparing current and desired headings-suggesting a more basic function for ce

144 d synthetic strategy for construction of the desired heterocycles featuring alpha-amino ynone generat

145 models to identify APIs that can achieve the desired high concentrations in nano-liposomes by remote

146 of-of-concept experiments show that multiple desired holographic images can be realized in real time

147 When desired, however, streptavidin plus the biotinylated bai

148 Importantly, in many cases the desired human tissues can be evaluated against new chemi

149 Windows may be exchanged depending on the desired imaging modality.

150 rm, for identifying optimal delivery for the desired immune activation in vivo.

151 not an adequate figure of merit, instead the desired impedance matching between the emitter and absor

152 In general, MBE growth has provided desired improvements in electronic mobility, epitaxy, an

153 uring and mapping single platelet forces are desired in both research and clinical applications.

154 ht trapping and field localization is highly desired in enhanced light-matter interaction, especially

155 eat opportunity to organize and retrieve the desired information efficiently from sizable databases.

156 intment near the patient's home was the most desired intervention (77%), followed by reminder message

157 's home and a reminder message were the most desired interventions to facilitate follow-up.

158 e of a slight excess of the left halves, the desired ketones were isolated in yields of 80-90 %.

159 unclear how fungal NRPSs create products of desired length.

160 the key design criteria needed to achieve a desired level of public health benefit.

161 cterial species while controlling the FDR at desired levels.

162 be designed by precycling an electrode in a desired Li- or Na-based electrolyte, and that ionic tran

163 tion, enabling the system to be tuned to the desired load and to clear the working memory of currentl

164 possible to precisely position the line at a desired location.

165 hen deposit them (in vacuum-off mode) in the desired location.

166 can be judiciously compressed and focused at desired locations, paving the way to such control in any

167 ation and structured light conversion in the desired manner.

168 rough space to direct an addressee towards a desired mental state.

169 alloys as a reaction solvent and co-alloyed desired metals into the melt.

170 at is used to selectively transmit ions of a desired mobility.

171 the UAV hovers in the air, the power on the desired mode fluctuates by 2.1 dB, while the crosstalk t

172 ves in the air, the power fluctuation on the desired mode increases to 4.3 dB and the crosstalk to th

173 other mode is -19 dB below the power on the desired mode; and (b) when the UAV moves in the air, the

174 c epitopes on the target molecule to exert a desired modulation of biological function.

175 of polymers that may be functionalized with desired moieties arrayed in a controlled fashion, the ut

176 validation on a cobalt-C3N4 catalyst with a desired molecular configuration, which possesses compara

177 aightforward synthetic approach delivers the desired molecular scaffolds in high yields (up to 82%) w

178 s and siRNAs, and can target essentially any desired mRNA.

179 o accelerate synthesis of large libraries of desired mutants through design and efficient organizatio

180 e to the transformation efficiency, with the desired mutation being found in essentially all transfor

181 e successfully gene edited demonstrating the desired mutation.

182 sgRNA and a targeting construct to introduce desired mutations.

183 hed between the yolk and shell, leads to the desired nanocup morphology.

184 ity studies, and quality control because the desired nanostructures are often far from thermodynamic

185 ntify strategies for optimizing the yield of desired nanostructures from the molecular self-assembly

186 ete epimerization to exclusively deliver the desired natural product (-)-claulansine D in quantitativ

187 Desired network connectivity patterns were reinforced in

188 works as leak propagation can interfere with desired network function.

189 e hindered by the difficulty of manipulating desired neural fates in the brain without complex geneti

190 theory, we find that the formation energy of desired Ni(4+) sites is systematically modulated by inco

191 f requesting or drawing their attention to a desired object or food.

192 aterials remains an alluring goal and a much desired objective.

193 and a rational annealing process led to the desired oligomer.

194 Each target test tube contains a set of desired "on-target" complexes, each with a target second

195 ative approach resulting in isomers with the desired orientation of the nucleobase.

196 e single-crystal blue-phase domains with the desired orientation over large regions.

197 ecies' metabolisms will integrate to reach a desired outcome is a difficult problem that has been stu

198 ional chemical methods failed to deliver the desired outcome, an engineered cytochrome P450 enzyme wa

199 ntexts where high resolution TERS is not the desired outcome.

200 gy, even when it is beneficial, to achieve a desired outcome.

201 -wide markers to select individuals with the desired overall combination of breeding traits.

202 t lowering of the activation barrier for the desired pathway.

203 lar construction of foldable structures with desired performance and manufacturing scalability.

204 revented the fabrication of devices with the desired performance and switching behavior.

205 ized cells yielded numerous mutants with the desired phenotypes, and the insertion sites in 18 of the

206 n deploy a given subset of them to produce a desired phenotypic outcome without undesired cross talk

207 can be designed to produce structures with a desired physical property rather than a specific shape.

208 hastic sampling as soon as exhaustiveness at desired precision is reached, thereby improving sampling

209 3C (DS), which stabilizes Env in the vaccine-desired prefusion-closed state.

210 law of momentum conservation rules out many desired processes in optical microresonators.

211 derwent reductive cyclization to provide the desired product in 60% yield.

212 challenges originate from the fact that the desired product of the combined process is formed by a b

213 ' (usually a functional) group to obtain the desired product selectively.

214 alyst surface is essential for achieving the desired product selectivity.

215 s were easy to perform affording most of the desired products in 33-93% yields.

216 cid residues was carried out to generate the desired products in 47-88% yield and 90:10 to >98:2 Z:E

217 ketone precursors could directly lead to the desired products in a single operation while the reactio

218 mployed in this transformation providing the desired products in good yields.

219 mol % of the alkylating agent to afford the desired products in up to >98 % yield with >98 % anti-Ma

220 , and secondary sulfonamide also provide the desired products of esters, ethers, thioether, and terti

221 that purification must be used to obtain the desired products, titers of which are typically low and

222 yst design and achieve high selectivities to desired products.Understanding the mechanism of CO2 redu

223 eins could provide a 'blank slate' to evolve desired properties for drug delivery and other biomedica

224 ysical, and/or enzymatic means to obtain the desired properties for targeted encapsulation.

225 particular property adequately, or multiple desired properties simultaneously.

226 nt nanostructures to achieve various tunable desired properties simultaneously.

227 ed to achieve this anisotropic behavior with desired properties.

228 ps and rationally design nanostructures with desired properties.

229 used for generating metal nanocrystals with desired properties.

230 localization capability while changing other desired properties.

231 roach in constructing robust structures with desired properties.

232 cessary precondition for the optimization of desired properties.

233 hanism also decelerates DNA translocation, a desired property for sequencing and gene detection, allo

234 detect tyrosine phosphorylation and activate desired protein enzymes allowing the control of phagocyt

235 on, and to define the design space where the desired quality criterion was met.

236 ch can be used to transform materials into a desired quantum state.

237 steroid-, and sugar-derived ones, leading to desired quinolines and naphthydrines with good yields.

238 mical resolution method achieve 65% yield of desired (R,S)-diastereomer 12.

239 ed sodium carbonate (Na2CO3), as well as the desired reaction product sodium peroxide (Na2O2).

240 in saliva and at the same time to obtain the desired release profile in gastrointestinal tract.

241 determine the optimal sequencing depth for a desired resolution.

242 ght interfere with the induction of the more desired responses to tier-2 epitopes.

243 rovided, by which users can easily get their desired results without needing to go through the compli

244 ction and in vivo tracking of TEMCs with the desired RNAs.

245 al and improve the limit of detection to the desired sensitivity.

246 tions from Internet users to obtain ideas or desired services, has grown significantly to fill this n

247 the implanted cells ensuring they reach the desired sites in vivo.

248 o fabricating particulate drug carriers with desired size and shape.

249 and alpha1AT, resulting in serpins with the desired specificity profile.

250 ts that are difficult to break down into the desired squares.

251 nodes is required to steer the network to a desired state within a relatively small time window.

252 des and the minimum time required to reach a desired state.

253 ) nodes to steer a complex network towards a desired state.

254 s strategies forcing a set of targets into a desired steady state.

255 The desired structural motif was formed in moderate to good

256 ands to fold one long scaffold strand into a desired structure, has provided access to megadalton-sca

257 homogeneity and in adequate amounts for the desired study.

258 functional delivery of intact drug into the desired subcellular compartment, however, it is critical

259 -coupling is used for the elaboration of the desired substituted dienes which will be involved in the

260 sequent decarboxylation, which liberates the desired sulfonyl amidines, generating N2 and CO2 as the

261 lay foundation for controlled fabrication of desired superlattice with tailored property.

262 poorly understandable toward achievement of desired superlattice.

263 iple based on preassembled components of the desired superstructure and programmed nearest-neighbour

264 control networks to infer perturbations with desired systems-level outcomes.

265 that their steady state is chosen from some desired target distribution that has finite support in [

266 ser-friendly interface to design cshRNAs for desired target genes.

267 dard protocols remains inefficient, yielding desired targeted alleles at a rate of approximately 1-5%

268 sform their plastic motor sequences to match desired targets.

269 wound dressings that can deliver drugs with desired temporal patterns.

270 The desired tertiary alcohols were isolated in up to 97 % yi

271 With bifunctional squaramide catalyst, the desired tetralone products are obtained with high enanti

272 pacity and viscosity, homogeneous structure, desired texture, and physicochemical high stability duri

273 stribution, confirming its high quality as a desired therapeutic.

274 in which maximum quantification accuracy is desired, this noninvasive dual-window acquisition with k

275 ly delivered into cells and activated at the desired time can contribute to understanding translation

276 oengineered constructs reproducibly generate desired tissue architectures.

277 hrough this journey, and deliver them to the desired tissue.

278 For many of these applications, it is much desired to have a solid-state structure that reversibly

279 ic fibers under ambient conditions is highly desired to identify the polymer, the finishes applied an

280 imics of these natural structures are highly desired to improve distribution of stresses at interface

281 It is thus highly desired to turn bulk and multilayer MX2 into direct band

282 hem, and implement their own instance of the desired tool.

283 lity of several of these proteins might be a desired trait as part of a mechanism enabling Chlamydomo

284 omycin, metronidazole, and fidaxomicin) is a desired trait in such probiotic species, we screened sev

285 nologies for genetic manipulation to achieve desired traits such as virus resistance.

286 develop combinations of alleles that provide desired traits.

287 ics and the point-to-point control along the desired trajectories.

288 that are both sufficiently reactive for the desired transformation and stable in vivo.

289 of 156 mAh g(-1); Mn and Fe are the two most-desired transition metals for electrodes because they ar

290 he top valence subband, which results in the desired transverse-electric polarized emission.

291 nger follow-up and controls, this may be the desired treatment modality.

292 bres inserted into the prostate to cover the desired treatment zone and subsequent activation by lase

293 genation with trifluoroethanol to afford the desired trifluoromethylaryl ether.

294 cross-coupling with haloarenes furnished the desired trisubstituted imidazole scaffolds.

295 LAIV may be a first step toward the desired universal influenza vaccine.

296 along a single Si nanowire can be tuned to a desired value (between crystalline and amorphous limits)

297 uch potential is the closest observed to the desired value of platinum at (-0.25 V vs. SCE).

298 fides, and amines, were transformed into the desired vicinal dichlorides with high chemoselectivity.

299 light emitting devices with 2D materials at desired wavelengths.

300 accelerate the development of cultivars with desired yield potential, quality, and enhanced adaptatio