ライフサイエンスコーパス: desmosine

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1 Serial desmosine analysis from en face sections indicated the i

2 Desmosine analysis indicated that elastin cross-links in

3 in and fibulin-5 mRNAs, increased amounts of desmosine and insoluble elastin, and increased depositio

4 neralized method for an accurate analysis of desmosine and isodesmosine as biomarkers in many types o

5 presence of proteins (such as elastin), and desmosine and isodesmosine cross-linkers in the microcal

6 e measurement of two crosslinking molecules, desmosine and isodesmosine, as biomarkers of elastic tis

7 short repeat, [VPGVG]5, an alanine pentamer, desmosine, and isodesmosine sites with and without gluco

8 well as the elastin cross-linking amino acid desmosine, and that it co-localizes with fibrillin-1-pos

9 A donors had significantly reduced levels of desmosine compared with those of CAs.

10 protein, FBLN5 and tropoelastin protein, and desmosine content in the vagina suggest that a burst of

11 Elastin content, measured as desmosine cross-links, decreased significantly in the fi

12 preterm birth (PICP, ICTP, MMP-2, TGF-beta1, desmosine, CTGF, TIMP-1).

13 Desmosine (D) and isodesmosine (I), the intramolecular c

14 The synthesized desmosine-d(4) is used as the internal standard to devel

15 Chemical synthesis of the deuterium isotope desmosine-d4 has been achieved.

16 ction, using a biochemical assay for urinary desmosine (DES), a specific marker for mature elastin de

17 ) to reduce the rate of urinary excretion of desmosine (DES), a specific marker of elastin degradatio

18 LOX activity, as assessed by desmosine (elastin cross-link) analysis, was reduced by

19 tide of type 1 collagen (ICTP), collagen VI, desmosine, matrix metalloproteinase 2 (MMP-2), tissue in

20 ed bronchiectasis provided blood samples for desmosine measurement, and 381 provided sputum for basel

21 of the alkyl amino acid substitution in the desmosine molecule and is stable toward acid hydrolysis;

22 genous pyridinium derivatives (pyridinoline, desmosine, pyridoxine, pyridoxamine, pyridoxal, pyridoxa

23 s from each group of donors was evaluated by desmosine radioimmunoassay.

24 berculosis patients compared to controls and desmosine, released during elastin degradation, was 2.4-

25 Pyridinoline, but not desmosine, sensitized light-driven H2O2 production and i

26 Desmosine was correlated with sputum elastase (r = 0.42;

27 The enzymatic cross-links pyridinoline and desmosine were examined as candidate sensitizer chromoph

28 IONALE: Sputum neutrophil elastase and serum desmosine, which is a linked marker of endogenous elasti

29 ine the association of elastase activity and desmosine with exacerbations and lung function decline i

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