ライフサイエンスコーパス: destine

1 This modification destines activated caspase-8 molecules to rapid proteaso

2 Diapause-destined adult females and nondiapausing counterparts af

3 pically targeted cargo delivery, for both PM-destined and secretory cargo, providing the first eviden

4 Subjecting gyne-destined brood to simulated AD-frequency vibrations caus

5 body, galectin-3 colocalizes with melanosome-destined cargo, specifically tyrosinase and Tyrp-1.

6 All outflow tract-destined cells are intermingled with those that will con

7 de novo DNA methyltransferase to the lineage-destined daughter cell facilitates epigenetic adaptation

8 d potential use of fodder potato protein not destined directly for food purposes as the suitable prod

9 or, and the ability to lay unfertilized male-destined eggs.

10 function in mesenchymal precursors that are destined for a chondrogenic lineage during endochondral

11 pping with the growth cones of other neurons destined for a different layer through the redundant fun

12 The developing mammalian brain is destined for a female phenotype unless exposed to gonada

13 the fate of each mitochondrion, to be either destined for a subsequent fusion or eliminated by autoph

14 espiratory drive to generate late-E activity destined for AbN motoneurones.

15 Embryos in seeds destined for abortion failed to undergo normal morphogen

16 r proteins that recruit cytoplasmic proteins destined for active nuclear import to the nuclear transp

17 Dysplastic ACF, once postulated as the ACF destined for adenomatous transformation, have been rarel

18 vivo PI3K-delta inhibition in CD8(+) T cells destined for adoptive transfer, enhancing their survival

19 ertoire of states than are sequence segments destined for alpha-helix.

20 ived from intermediates of the OPPP that are destined for amino acid production, restores wild-type l

21 ominantly to convert a RPC subpopulation not destined for an RGC fate to adopt that fate.

22 may be coinnervated by CN3 branches normally destined for any other rectus EOMs.

23 ptotic cell extrusion." Specifically, a cell destined for apoptosis signals its live neighboring epit

24 During extrusion, a cell destined for apoptosis signals its neighboring cells to

25 ector cells (SLECs), a majority of which are destined for apoptosis, and the memory precursor effecto

26 iew addresses the potential of immunosensors destined for application in food and environmental analy

27 ely on the same crops, although the fraction destined for aquaculture is presently small ( approximat

28 information revealed that sequence segments destined for beta-sheet in the final native fold are ene

29 e, whereas structure formation for sequences destined for beta-strand is far less probable.

30 tion and in assuring quality of preparations destined for biomedical applications.

31 or the conformational maturation of proteins destined for cell-surface display or export.

32 ivory price and increased seizures of ivory destined for China.

33 lar structure storing transmembrane proteins destined for cilia during the early phase of ciliogenesi

34 and to examine the metabolic status of iPSCs destined for clinical applications.

35 lapse, without subjecting those patients not destined for CNS relapse to unnecessary and potentially

36 mRNAs, perhaps cotranscriptionally, that are destined for cytosolic degradation as part of the mechan

37 of mRNAs from translation to an mRNP complex destined for decapping.

38 se RNAs represent dead-end products normally destined for decay by TbDSS-1 in an RNA surveillance pat

39 ly equal mitoses the segregation of proteins destined for degradation (Smad1 phosphorylated by MAPK a

40 ER-resident proteins destined for degradation are dislocated into the cytosol

41 They sort proteins destined for degradation into internal vesicles while in

42 Multivesicular bodies (MVBs) deliver cargo destined for degradation to the vacuole or lysosome.

43 tering bulk cytoplasm and/or selected cargos destined for degradation upon autophagosome fusion with

44 hesive junctional PCP complexes appear to be destined for degradation upon internalization.

45 central role in processing cellular proteins destined for degradation, but little is currently known

46 internalized AChRs, which would otherwise be destined for degradation, into synaptic sites.

47 se aggregated proteins are not misfolded and destined for degradation.

48 ackaging, and transport of synaptic material destined for degradation.

49 The tegument comprises at least 20 proteins destined for delivery into the host cell.

50 -coated vesicles or transport carriers (TCs) destined for delivery to endosomes.

51 in the selection and packaging of the cargo destined for delivery to the cilium.

52 tracking along a subset of tracheal branches destined for destruction.

53 ed axon-glial interactions in those children destined for diagnosis of MS.

54 em cell lineages is that stem cell daughters destined for differentiation undergo several transit amp

55 to exclusively reduce disulfides in proteins destined for dislocation to the cytosol for degradation.

56 oming directly out of use or postuse storage destined for disposal or collection, which encompasses a

57 CGIs destined for DNA methylation show reduced protective H3K

58 , FOXO1 was expressed in a fraction of cells destined for DZ reentry.

59 served, suggesting that the weaker input was destined for elimination.

60 hough this technique can save eyes otherwise destined for enucleation, ocular salvage may be accompan

61 binds to a misfolded nonglycosylated protein destined for ERAD, but not to the properly folded wild-t

62 ugh most circulating iron in blood plasma is destined for erythropoiesis, the mechanisms by which ery

63 -Atp8p complex that aggregated into polymers destined for eventual proteolytic elimination.

64 ectly or indirectly with the cargo molecules destined for exit.

65 process, and also acidification of vesicles destined for exocytosis.

66 Proteins destined for export across the cytoplasmic membrane via

67 Proteins destined for export are synthesized in the endoplasmic r

68 that are silent in embryonic stem cells, but destined for expression during differentiation, includes

69 rished children and for identifying children destined for further growth shortfalls.

70 g myo-inositol for phosphatidylinositol (PI) destined for GPI synthesis.

71 Metabolic resources normally destined for growth and development are redirected towar

72 Their presence in food destined for human consumption and in air samples has be

73 These shellfish, when destined for human consumption, undergo a depuration ste

74 an important potential contaminant in honey destined for human consumption.

75 eostasis and the quality of poultry products destined for human consumption.

76 Proteins destined for import into the nucleus contain nuclear loc

77 artitions into the aqueous phase where it is destined for interaction with ABCA1 transporters, thereb

78 ng of clathrin and adaptors around receptors destined for internalization.

79 CRgammadelta(+) T cells in the fetal thymus, destined for intraepithelial locations.

80 The method was applied to biosolids destined for land application.

81 as not filled by the later-generated neurons destined for layer II, indicating that there is no subse

82 y endosomal sorting of EGFR between pathways destined for lysosomal degradation and recycling.

83 n internalized receptors and other cargo are destined for lysosomal degradation, they are ubiquitinat

84 which can engage ubiquitinylated substrates destined for lysosomal degradation.

85 questers bulk cytoplasm, or a specific cargo destined for lysosomal/vacuolar delivery.

86 nsure the continued formation of fatty acids destined for membrane phospholipid even though 24% of th

87 ntermediate containing intralumenal vesicles destined for membrane protein degradation in the lysosom

88 )/IUGR(mat), respectively) control-fed rats, destined for MetS, had a distinct metabolome at weaning

89 t allows them to capture membrane organelles destined for MT minus end-directed transport.

90 ntermediate progenitor cells (IPCs) that are destined for neuronal maturation in the hippocampal subg

91 d from the U.S. in 2010, of which 78-81% are destined for non-OECD countries.

92 enables characterization of waste materials destined for nuclear waste repositories as well as exten

93 ating the availability of purine nucleotides destined for nucleic acid synthesis.

94 referentially trafficked into acyl-CoA pools destined for phosphatidylinositol incorporation.

95 y amine and forming quaternary intermediates destined for phthalideisoquinolines and antimicrobial be

96 abundance of PHT1s in the secretory pathway destined for plasma membranes, but also provides a datab

97 tified distinct signatures that marked cells destined for positive selection versus apoptotic deletio

98 a wastewater treatment plant producing water destined for potable reuse.

99 l degradation of proteins in the cytosol and destined for presentation by MHC class I (MHC-I) are ass

100 bits the clearance of ubiquitinated proteins destined for proteasomal degradation by delaying their d

101 e cytosolic heat-induced Rsp5 substrates are destined for proteasomal degradation, whereas other Rsp5

102 n targets of SspH2-catalyzed Ub transfer are destined for proteasomal destruction.

103 , implying that a smaller pool of betaAPP is destined for proteasomal processing.

104 ophobic substrates in the cytoplasm that are destined for proteasomal recycling.

105 subpopulation of betaAPP molecules that are destined for proteasome degradation.

106 lipid carrier of the oligosaccharide moiety destined for protein N-linked glycosylation.

107 During developmental remodeling, neurites destined for pruning often degenerate on-site.

108 es that sweep into the population may not be destined for rapid fixation.

109 ect the general population, freezing of meat destined for raw or undercooked consumption is the most

110 suPAR appears to be higher in cases of FSGS destined for recurrence and merits further evaluation.

111 protein sorting with a majority of proteins destined for recycling, rather than MVB targeting.

112 Interestingly, target sites that were destined for release from Ago2 upon stress were depleted

113 g was performed through the section of bowel destined for resection, and slope of enhancement, time t

114 of at least two distinct pools of Abeta; one destined for secretion and the other being produced and

115 ns in the sorting and processing of proteins destined for secretion from eukaryotic cells.

116 have suggested that the majority of proteins destined for secretion in the haloarchaea are trafficked

117 Cargo proteins destined for secretion through T9SS carry a recognition

118 is and folding of newly synthesized proteins destined for secretion, such as insulin.

119 culum is a crucial step for folding proteins destined for secretion.

120 Experimental mice destined for spaceflight and mice that remained on the g

121 carbon fixation, indicating that some carbon destined for specialized metabolism is likely fixed with

122 ing material throughout the dendrite that is destined for spines, they are not thought to directly in

123 brane proteins for proper folding in samples destined for structural studies.

124 scle cells (SMCs) around those aortic arches destined for survival and reorganization, and identify t

125 er synthesis in neuronal perikarya, proteins destined for synapses and other distant axonal sites are

126 mine into neurons for synthesis of glutamate destined for synaptic release is not strongly dependent

127 ons that eliminate IGF signaling cause axons destined for targets in the lateral bulb to shift to ect

128 , specific sorting of proteins into vesicles destined for the apical and basolateral domain is requir

129 Proteins destined for the cell surface are first assessed in the

130 that serve as recruitment sites for proteins destined for the centrosome and cilium.

131 r findings indicate that structural proteins destined for the ciliary axoneme are attached to the out

132 icles not only for the transport of proteins destined for the ciliary membrane but also for the trans

133 r cortices specify descending neural signals destined for the downstream interneurons and motoneurons

134 ding to cargo packaging into coated vesicles destined for the endolysosomal system.

135 Tail-anchored (TA) membrane proteins destined for the endoplasmic reticulum are chaperoned by

136 ately one-third of the proteome is initially destined for the eukaryotic endoplasmic reticulum or the

137 Most proteins destined for the extracellular space require disulfide b

138 (TA) proteins released from the ribosome and destined for the GET (Guided Entry of TA proteins) pathw

139 uired for the terminal maturation of neurons destined for the glomerular layer.

140 teins from endosomes into retrieval pathways destined for the Golgi apparatus and the plasma membrane

141 Vesicles and other carriers destined for the Golgi apparatus must be guided to the c

142 ay of baculovirus integral membrane proteins destined for the inner nuclear membrane (INM).

143 volution of biogenic amines in Canadian pork destined for the Japanese market.

144 Most newly synthesized proteins destined for the lysosome reach this location via a spec

145 en proposed that iron-sulfur [Fe-S] clusters destined for the maturation of [Fe-S] proteins can be pr

146 Proteins destined for the mitochondrial matrix are targeted to th

147 ls proliferation and migration of adult NSCs destined for the mouse olfactory bulb (OB).

148 neurons in the human subventricular zone are destined for the olfactory bulb--we describe a major mig

149 mmals generates large numbers of new neurons destined for the olfactory bulb.

150 of birth of different types of interneurons destined for the olfactory bulb.

151 Regardless of whether they are destined for the outer or inner membrane, the intermembr

152 Most proteins destined for the peroxisomal matrix depend on the peroxi

153 STELLA may identify a subpopulation of cells destined for the PGC lineage, our findings reveal that i

154 whether glucose transporters (GLUTs, SGLTs) destined for the plasma membrane are active during ER tr

155 regulating the fission of transport carriers destined for the plasma membrane.

156 ts cotranslational translocation of proteins destined for the secretory pathway.

157 specifically recognizes TMDs of TA proteins destined for the secretory pathway.

158 erograde and retrograde trafficking of cargo destined for the sensory cilium and this balance require

159 co-transcriptionally separate the pre-rRNAs destined for the small and large subunit.

160 riptional cleavage step that separates rRNAs destined for the small and large subunit.

161 ckness, mainly due to elimination of neurons destined for the superficial layers.

162 Collectively, our data suggest that MOSP destined for the TDE OM follows the canonical BAM pathwa

163 Proteins destined for the thylakoid lumen of chloroplasts must cr

164 al vesicles (ILVs) containing cargo proteins destined for the vacuolar/lysosomal lumen.

165 TORC1 interacts with multiple cargo proteins destined for the Vid pathway and plays an important role

166 rationally design chemically modified siRNA destined for therapeutic use.

167 ranscribed into RNA molecules that are never destined for translation into proteins.

168 ll therapy, we strongly recommend that cells destined for transplant be monitored throughout their pr

169 neurons whereas E16.5 cultures contain cells destined for upper layers.

170 of perfluoroalkyl acids (PFAAs) in biosolids destined for use in agriculture has raised concerns abou

171 tals (copper, zinc and cadmium) in biosolids destined for use in agriculture.

172 ing and standardizing MDI-albumin conjugates destined for use in clinical research.

173 Ceramics destined for use in hostile environments such as nuclear

174 ular mechanisms that supply neurotransmitter destined for vesicle filling, the endogenous transmitter

175 re highly expressed in queen- than in worker-destined late-instar larvae.

176 RNA-binding protein in the translation of ER-destined mRNAs.

177 s, whereas overexpression of CXCR4 in non-SG-destined NCCs induces them to migrate aberrantly toward

178 h fragment at the S3 site produces a nuclear-destined Notch intracellular domain (NICD).

179 plicable not only to photovoltaic or display-destined organic semiconductors but also to explaining t

180 Sorting signals for apically destined proteins are highly diverse and can be present

181 Encoding organelle-destined proteins in the nucleus allows for host control

182 sh5 (MutSgamma) complex, which stabilizes CO-destined recombination intermediates and members of the

183 cronuclear-limited sequences to macronuclear destined sequences at two of these loci.

184 S) are excised, followed by rejoining of MAC-destined sequences, while fragmentation occurs at conser

185 t preferentially binds endoplasmic reticulum-destined TA proteins and directs them to the GET pathway

186 a template, adding a short peptide tag that destines the aborted protein for destruction.

187 nglion mediated partly by early-born neurons destined to a myelinated phenotype participate in fating

188 ry cell production, and in its absence cells destined to a secretory phenotype instead adopt an absor

189 oduced at specific developmental periods and destined to a specific neocortical layer.

190 socioemotional skills are unresolved issues destined to attract future research.

191 on-induced association with cellular cargoes destined to autophagic double membrane structures.

192 d kinase that phosphorylates protein domains destined to be extracellular.

193 search, where every established "rule" seems destined to be overturned.

194 The part of the RS domain destined to be phosphorylated at later stages of the rea

195 of the basic RS domain of ASF/SF2, which is destined to be phosphorylated, is bound to an acidic doc

196 ermanent cartilage or hypertrophic cartilage destined to be replaced by bone has not yet been possibl

197 he mammalian genome codes for messenger RNAs destined to be translated into proteins, and it is gener

198 Some effector proteins are secreted and are destined to be translocated and function inside host cel

199 teins, whereas another subset of proteins is destined to be transported across the cell wall into the

200 The daughter cell destined to become a neuron was derived from the more ap

201 diopulmonary resuscitation (CPR) of a person destined to become an organ donor has been associated wi

202 gen, with lower oxygen tension in the region destined to become articular cartilage and higher oxygen

203 er due to the recruitment of cells, normally destined to become cranial epidermis, into the otic doma

204 showed that a subset of recombination events destined to become crossover products increased the freq

205 cartilage or hypertrophic cartilage that is destined to become endochondral bone.

206 cally upregulated in ventricular progenitors destined to become ependymal cells, but not in NSCs, and

207 o have earlier detection of a tumor that was destined to become large.

208 lial cells of the mouse airways and ependyma destined to become MCCs.

209 t STAT5 signals diverted thymocytes normally destined to become naive T cells into the Treg cell line

210 nd identified in regions of tendon which are destined to become rapidly mineralized around 14 weeks o

211 e initiation of DNA replication at the locus destined to become silenced nor the passage of a replica

212 riphosphatase, Cdc42, to the cortical region destined to become the "front" of the cell.

213 Before this time point, the epithelial layer destined to become the adult midgut is devoid of endocri

214 l differentiation in regions of the eye disc destined to become ventral head tissue.

215 high early in the colony cycle, when larvae destined to become workers are being reared, and low lat

216 n prevented the exit of cargo from the Golgi destined to both the plasma membrane and the late endoso

217 Proteins destined to circulate in the blood are first folded and

218 axon segments distal to transection that are destined to degenerate.

219 ' gestation and prior to intervention, women destined to develop a short cervix (n = 36) exhibited hi

220 olecular vasopermeability localized to sites destined to develop arthritis, augmenting its severity.

221 s before progressive decline in a population destined to develop illness.

222 rns, of which 2 clearly distinguish patients destined to develop NI from those who did not.

223 the second trimester to identify pregnancies destined to develop preeclampsia.

224 Borrelia burgdorferi, in the joints of mice destined to develop severe arthritis (C3H) or mild disea

225 Persons destined to develop the disease by virtue of fully penet

226 protective barrier, epithelia extrude cells destined to die by contracting a band of actin and myosi

227 onse to Ag during the inflammatory phase are destined to die during termination of the immune respons

228 -apoptotic gene Bax showed that even neurons destined to die formed qualitatively and quantitatively

229 hils as terminally differentiated leukocytes destined to die or to participate primarily in host inna

230 Extrusion occurs by cells destined to die signalling to surrounding epithelial cel

231 ription in promoting CED-3 activity in cells destined to die, it remains unclear whether the temporal

232 mediately after ischemia rescues CA1 neurons destined to die.

233 l CA1, seizures activate REST in CA3 neurons destined to die.

234 that provide acute protection but are often destined to die.

235 e AMPA receptor subunit GluR2 in CA1 neurons destined to die.

236 rons that express cleaved caspsase-3 and are destined to die.

237 oding a functional B-cell receptor (BCR) are destined to die.

238 presses REST expression, and rescues neurons destined to die.

239 t embryos, precursor cells that are normally destined to differentiate as beta cells instead take on

240 cells producing high-affinity antibodies are destined to differentiate into memory B cells and plasma

241 aining stem cell identity and the other cell destined to differentiate.

242 Persistent spines that were destined to disappear showed, on average, reduced PSD-95

243 expansion potential are limited and they are destined to eventually stop proliferating after a finite

244 urea nitrogen (BUN), could identify patients destined to experience adverse outcomes associated with

245 ng to identify more precisely those patients destined to experience relapse, which would allow more t

246 ought to develop stopping rules for patients destined to fail boceprevir-based combination therapy in

247 , suggesting that chronic-phase CML patients destined to fail imatinib have more advanced disease tha

248 onse" at 6 and 12 months identified patients destined to fare badly, although criteria at 18 months w

249 Patients destined to fare poorly can be identified early during t

250 months is the best way to identify patients destined to fare poorly, thereby allowing early clinical

251 Pre-migratory neural crest mesenchyme destined to form bone in the mandible was transplanted f

252 e, which targets undifferentiated mesenchyme destined to form bone.

253 rimordium (PLLP) a group of about 100 cells, destined to form sensory structures, that migrates from

254 ich enclose viroplasm consisting of proteins destined to form the cores of mature virions.

255 ere is extensive reorganisation of the cells destined to form the eyes, telencephalon and diencephalo

256 We show that at the cap stage, cells destined to form the follicle are still competent to for

257 rating NCCs express CXCR4 and this subset is destined to form the neural core of the sympathetic gang

258 y for specification of the prosensory domain destined to form the organ of Corti.

259 rned, and the anterior region is known to be destined to form the outflow tract and right ventricle.

260 errant migration of granule cell progenitors destined to form the posterior-most lobule causes this u

261 oximately one third of a cell's proteins are destined to function outside the cell's boundaries or wh

262 calized site of contact between the bilayers destined to fuse.

263 ctates the number of postmitotic progenitors destined to give rise to the hair cells and supporting c

264 In neurons destined to harbor latent virus (checkpoint 3), HSV hija

265 -143 and miR-145, in cervical cells of women destined to have a PTB.

266 or example, recovery occurs slowest in those destined to have less successful outcomes.

267 nt health threat and their levels in seafood destined to human consumption are regulated in many coun

268 oteasome is a specialized type of proteasome destined to improve major histocompatibility complex (MH

269 , and human conflicts, dementia incidence is destined to increase in the developing world in tandem w

270 ental process in the mosquito vector and are destined to infect the mammalian liver.

271 roblasts and essentially all definitive HPCs destined to initially seed the fetal liver after E9.5 ar

272 lead to metastasis and be a marker for cells destined to metastasize.

273 yopherinbeta1 transport-receptor and cargoes destined to nuclear import.

274 dymal cells continuously produce new neurons destined to olfactory bulb.

275 of KLRG1(hi) CD8+ T cells, which are usually destined to perish during contraction, without inducing

276 These data indicate that GOLD36 is a protein destined to post-ER compartments and suggest that its ex

277 18 had big size and oval form so it could be destined to potato chips industry.

278 show that Neurod1-expressing RPCs, which are destined to produce amacrine and photoreceptor cells, ca

279 ation of the GGTase-I-encoding gene in cells destined to produce lung tumors driven by oncogenic K-Ra

280 Nano-enabled products are ultimately destined to reach end-of-life with an important fraction

281 D1, responds well to initial therapy but is destined to relapse.

282 template DNA are segregated to the daughter destined to remain a stem cell, thus insuring lifetime g

283 that become mineralized compared to collagen destined to remain nonmineralized.

284 ve was to learn whether they influence cells destined to replenish the immune system.

285 Connectivity of males destined to rise did not change over time but increased

286 that the number of DCD kidney transplants is destined to rise in the UK, we believe that ATG is a val

287 wn, this is a rapidly emerging field that is destined to suggest novel antiviral therapies.

288 bed ribbon around midcell where septation is destined to take place.

289 ow distinct migration pathways of POMC cells destined to the anterior and intermediate lobes.

290 rk, regulating fission of transport carriers destined to the cell surface.

291 ed protein (GET) pathway selects TA proteins destined to the endoplasmic reticulum (ER) utilizing dis

292 lyzes the transfer of tail-anchored proteins destined to the endoplasmic reticulum from Sgt2 to the c

293 upling of transport and translation of mRNAs destined to the remote areas such as axons.

294 Their target proteins are destined to transit cellular membranes during their bios

295 Proteins destined to travel this secretion pathway are targeted t

296 characterizing future cell therapy products destined to treat endothelial dysfunctions.

297 minority of ulcerative colitis (UC) patients destined to undergo neoplastic progression.

298 ean many threatened species might already be destined toward extinction.

299 ciliary architecture via regulation of cilia-destined trafficking.

300 -Golgi network (TGN) of plasma membrane (PM)-destined transport carriers.