ライフサイエンスコーパス: destined to

1 nglion mediated partly by early-born neurons destined to a myelinated phenotype participate in fating

2 ry cell production, and in its absence cells destined to a secretory phenotype instead adopt an absor

3 p neither B(mem) nor long-lived PCs, and are destined to a short-lived PC fate.

4 oduced at specific developmental periods and destined to a specific neocortical layer.

5 and is preferentially expressed within cells destined to adopt the non-hair fate.

6 socioemotional skills are unresolved issues destined to attract future research.

7 on-induced association with cellular cargoes destined to autophagic double membrane structures.

8 rs, and any errors made by the daughters are destined to be discarded.

9 natural populations that is deleterious and destined to be eliminated and the fraction of fixed diff

10 This may influence the choice of individuals destined to be exposed to higher than normal doses of ra

11 d kinase that phosphorylates protein domains destined to be extracellular.

12 peptide sites in the nascent chains that are destined to be glycosylated.

13 search, where every established "rule" seems destined to be overturned.

14 DNA between recognition and cleavage of DNA destined to be packaged.

15 regions in replicating and recombining T4DNA destined to be packaged.

16 The part of the RS domain destined to be phosphorylated at later stages of the rea

17 of the basic RS domain of ASF/SF2, which is destined to be phosphorylated, is bound to an acidic doc

18 Why only specific proteins are destined to be processed by caspases during cell death i

19 ls in which loxP - flanked DNA sequences are destined to be removed from the genome by Cre-mediated r

20 ermanent cartilage or hypertrophic cartilage destined to be replaced by bone has not yet been possibl

21 evels of MCMV-inoculated eyes of normal mice destined to be resistant to retinitis.

22 formed in the central region of the myotome, destined to be synapse-rich, before axons extended and e

23 ture of the DNA lesion and the incoming dNTP destined to be the complementary partner.

24 he mammalian genome codes for messenger RNAs destined to be translated into proteins, and it is gener

25 Some effector proteins are secreted and are destined to be translocated and function inside host cel

26 teins, whereas another subset of proteins is destined to be transported across the cell wall into the

27 The daughter cell destined to become a neuron was derived from the more ap

28 diopulmonary resuscitation (CPR) of a person destined to become an organ donor has been associated wi

29 as many as 50% of newly produced B cells are destined to become anergic.

30 gen, with lower oxygen tension in the region destined to become articular cartilage and higher oxygen

31 er due to the recruitment of cells, normally destined to become cranial epidermis, into the otic doma

32 showed that a subset of recombination events destined to become crossover products increased the freq

33 Even though the majority of cells destined to become dopamine neurons are generated in the

34 expression of regulatory genes in the region destined to become dorsal thalamus.

35 cartilage or hypertrophic cartilage that is destined to become endochondral bone.

36 cally upregulated in ventricular progenitors destined to become ependymal cells, but not in NSCs, and

37 duce a 'neurogenic' phenotype in which cells destined to become epidermis switch fate and differentia

38 The average lifetime of a SNP destined to become fixed for a new allele between these

39 e-induced CTLs for the selection of epitopes destined to become immunotherapeutic for prostate cancer

40 or extrathymic differentiation by precursors destined to become intestinal intraepithelial T lymphocy

41 o have earlier detection of a tumor that was destined to become large.

42 lial cells of the mouse airways and ependyma destined to become MCCs.

43 which adoptively transferred CD8(+) CTL are destined to become memory T cells is ambiguous as most s

44 kly reverts to discrete dots in those nuclei destined to become micronuclei, whereas it remains diffu

45 t STAT5 signals diverted thymocytes normally destined to become naive T cells into the Treg cell line

46 es loss of both Nf1 alleles in Schwann cells destined to become neoplastic and may be exacerbated by

47 enicity requires both a loss of NF1 in cells destined to become neoplastic as well as heterozygosity

48 nsiently occurs in a large fraction of cells destined to become NK cells.

49 n of mRNAs of these two frequency classes is destined to become overwhelming relatively early in any

50 that p27(Xic1) is highly expressed in cells destined to become primary neurones and is essential for

51 nd identified in regions of tendon which are destined to become rapidly mineralized around 14 weeks o

52 e initiation of DNA replication at the locus destined to become silenced nor the passage of a replica

53 ays of gestation and at 10.5 days in regions destined to become skin.

54 bviate unnecessary treatment of patients not destined to become symptomatic.

55 riphosphatase, Cdc42, to the cortical region destined to become the "front" of the cell.

56 Before this time point, the epithelial layer destined to become the adult midgut is devoid of endocri

57 r in vitro labeling allows the regions of HS destined to become the antithrombin (AT)-binding sites t

58 e distal region of the optic vesicle that is destined to become the neural retina, suggesting a role

59 In vivo, precursor cells that are destined to become TrkA(+) neurons are born.

60 l differentiation in regions of the eye disc destined to become ventral head tissue.

61 high early in the colony cycle, when larvae destined to become workers are being reared, and low lat

62 able receptor-viral attachment proteins were destined to bind at steady state.

63 n prevented the exit of cargo from the Golgi destined to both the plasma membrane and the late endoso

64 c dynein binds to regions of stacks that are destined to bud because dynein is present in budded memb

65 g field of nonlinear photonic crystals seems destined to change this view dramatically.

66 Proteins destined to circulate in the blood are first folded and

67 eplicate or generate daughter cells that are destined to commit to mature cells of different specific

68 he point at which spores became irreversibly destined to complete the uncoating process even if the o

69 of traditional medical specialties and seems destined to continue to grow.

70 irst endoderm cells to express Hesx1 are not destined to contribute to the future embryo, but instead

71 r, in zebrafish embryos, the domain of cells destined to contribute to the spinal cord extends all th

72 or-mediated excitotoxicity may spare neurons destined to degenerate.

73 axon segments distal to transection that are destined to degenerate.

74 s, whether or not the activated T cells were destined to delete or survive, they were difficult to ex

75 ' gestation and prior to intervention, women destined to develop a short cervix (n = 36) exhibited hi

76 olecular vasopermeability localized to sites destined to develop arthritis, augmenting its severity.

77 s before progressive decline in a population destined to develop illness.

78 e with the basal cell nevus syndrome who are destined to develop large numbers of BCCs.

79 rns, of which 2 clearly distinguish patients destined to develop NI from those who did not.

80 Prediction of those women destined to develop preeclampsia remains elusive.

81 the second trimester to identify pregnancies destined to develop preeclampsia.

82 apid PSADT who were previously thought to be destined to develop progressive metastatic disease may a

83 Moreover, MCMV-inoculated eyes destined to develop retinitis during MAIDS also showed a

84 Borrelia burgdorferi, in the joints of mice destined to develop severe arthritis (C3H) or mild disea

85 Persons destined to develop the disease by virtue of fully penet

86 ostic tool for identifying those individuals destined to develop this disease.

87 defect of beta-cell function in individuals destined to develop type 2 diabetes and that this defect

88 ial in helping to better predict individuals destined to develop type 2 diabetes.

89 s, even though their spermatogenic cells are destined to die (bs/bs and qk/qk) or are programmed to u

90 n aggregates were accumulated in CA1 neurons destined to die 72 hr after 15 min of cerebral ischemia.

91 for Ca(2+) influx through AMPARs in neurons destined to die and implicate Ca(2+)-permeable AMPARs in

92 Many of the CA3 pyramidal neurons destined to die as a consequence of status epilepticus w

93 fection by preventing the apoptosis of cells destined to die because of growth factor deprivation.

94 protective barrier, epithelia extrude cells destined to die by contracting a band of actin and myosi

95 latory pathway determining the fate of cells destined to die by the default pathway of apoptosis.

96 unclear how a lytic gene expressed in cells destined to die can cause cancer.

97 onse to Ag during the inflammatory phase are destined to die during termination of the immune respons

98 d diaphorase-positive neurons which were all destined to die following administration of quinolinic a

99 -apoptotic gene Bax showed that even neurons destined to die formed qualitatively and quantitatively

100 striatal neural populations, including those destined to die in a rodent model of HD, and supports th

101 resent the neoplastic transformation of BCPs destined to die in the bone marrow.

102 Both IL-6KO and WT mice destined to die in the early stages of sepsis had substa

103 hils as terminally differentiated leukocytes destined to die or to participate primarily in host inna

104 Extrusion occurs by cells destined to die signalling to surrounding epithelial cel

105 In cells destined to die this IAP-mediated inhibition of caspases

106 n viable in the presence of TPA versus cells destined to die upon exposure to taxol or okadaic acid.

107 ription in promoting CED-3 activity in cells destined to die, it remains unclear whether the temporal

108 med cells by fusing cells that are otherwise destined to die.

109 ervation of specific brain regions and cells destined to die.

110 oter activity and gene expression in neurons destined to die.

111 rons that express cleaved caspsase-3 and are destined to die.

112 that provide acute protection but are often destined to die.

113 for Ca(2+) influx through AMPARs in neurons destined to die.

114 nas, although only a few of these cells were destined to die.

115 oding a functional B-cell receptor (BCR) are destined to die.

116 through AMPA receptors in pyramidal neurons destined to die.

117 presses REST expression, and rescues neurons destined to die.

118 mediately after ischemia rescues CA1 neurons destined to die.

119 l CA1, seizures activate REST in CA3 neurons destined to die.

120 e AMPA receptor subunit GluR2 in CA1 neurons destined to die.

121 prevent onset of death in neurons otherwise "destined to die."

122 treak in living embryos, and find that cells destined to different structures follow defined pathways

123 ferating transit amplifying cells, which are destined to differentiate after a finite number of cell

124 t embryos, precursor cells that are normally destined to differentiate as beta cells instead take on

125 In the absence of Zpg the stem cell daughter destined to differentiate dies.

126 ome plants is the selective killing of cells destined to differentiate into an unwanted sexual organ.

127 cells producing high-affinity antibodies are destined to differentiate into memory B cells and plasma

128 ge numbers of committed progenitors that are destined to differentiate into spermatozoa throughout li

129 re more adhesive than keratinocytes that are destined to differentiate.

130 aining stem cell identity and the other cell destined to differentiate.

131 Persistent spines that were destined to disappear showed, on average, reduced PSD-95

132 ough historically rooted, the two codes were destined to diverge quite early.

133 hat distinguish a preapoptotic cell from one destined to divide.

134 ys independent of APOE.Some individuals seem destined to escape AD, even over an extended lifespan.

135 expansion potential are limited and they are destined to eventually stop proliferating after a finite

136 xpansion, or is the universe underweight and destined to expand forever?

137 urea nitrogen (BUN), could identify patients destined to experience adverse outcomes associated with

138 ng to identify more precisely those patients destined to experience relapse, which would allow more t

139 rly in the course of therapy, those patients destined to experience treatment failure with a melanoma

140 R1+ cells in CX3CR1(+/GFP) animals and cells destined to express CX3CR1 in CX3CR1(GFP/GFP) knockouts.

141 cus to study the developmental fate of cells destined to express prx-1 in the prx-1 mutant background

142 ought to develop stopping rules for patients destined to fail boceprevir-based combination therapy in

143 , suggesting that chronic-phase CML patients destined to fail imatinib have more advanced disease tha

144 ore than a modern day version of phrenology: destined to fail, and fundamentally uninformative.

145 onse" at 6 and 12 months identified patients destined to fare badly, although criteria at 18 months w

146 Patients destined to fare poorly can be identified early during t

147 months is the best way to identify patients destined to fare poorly, thereby allowing early clinical

148 The E-Cbs typically resides within the DNA destined to form a macronuclear DNA molecule, but can al

149 Pre-migratory neural crest mesenchyme destined to form bone in the mandible was transplanted f

150 e, which targets undifferentiated mesenchyme destined to form bone.

151 d to competent host cells that are otherwise destined to form only extra-embryonic tissue.

152 paraxial mesoderm, and in its absence cells destined to form posterior somites differentiate along a

153 Cysts may ensure that oocytes destined to form primordial follicles acquire population

154 rimordium (PLLP) a group of about 100 cells, destined to form sensory structures, that migrates from

155 ich enclose viroplasm consisting of proteins destined to form the cores of mature virions.

156 we exchange pre-migratory neural crest cells destined to form the craniofacial dermis between them.

157 ere is extensive reorganisation of the cells destined to form the eyes, telencephalon and diencephalo

158 We show that at the cap stage, cells destined to form the follicle are still competent to for

159 rating NCCs express CXCR4 and this subset is destined to form the neural core of the sympathetic gang

160 y for specification of the prosensory domain destined to form the organ of Corti.

161 rned, and the anterior region is known to be destined to form the outflow tract and right ventricle.

162 errant migration of granule cell progenitors destined to form the posterior-most lobule causes this u

163 urrounding the region of the otocyst that is destined to form the semicircular canals.

164 The earliest known marker for cells destined to form the VMH is the orphan nuclear receptor,

165 oximately one third of a cell's proteins are destined to function outside the cell's boundaries or wh

166 o establish themselves in a site that is not destined to fuse with lysosomes.

167 odies to form tyrosinase-containing vesicles destined to fuse with premelanosomes.

168 the acrosomal vesicle, exposing the membrane destined to fuse with the egg.

169 calized site of contact between the bilayers destined to fuse.

170 Thus, embryonic endoderm destined to give rise to taste buds specifically attract

171 ctates the number of postmitotic progenitors destined to give rise to the hair cells and supporting c

172 the dorsolateral territory of the somite is destined to give rise to the hypaxial skeletal musculatu

173 The cells destined to go into the outflow myocardium fail to migra

174 In neurons destined to harbor latent virus (checkpoint 3), HSV hija

175 -143 and miR-145, in cervical cells of women destined to have a PTB.

176 or example, recovery occurs slowest in those destined to have less successful outcomes.

177 nt health threat and their levels in seafood destined to human consumption are regulated in many coun

178 oteasome is a specialized type of proteasome destined to improve major histocompatibility complex (MH

179 , and human conflicts, dementia incidence is destined to increase in the developing world in tandem w

180 ental process in the mosquito vector and are destined to infect the mammalian liver.

181 roblasts and essentially all definitive HPCs destined to initially seed the fetal liver after E9.5 ar

182 ons to sort and fasciculate with other axons destined to innervate the same glomeruli.

183 blood in response to cytokine exposure, are destined to later return to marrow, an observation that

184 50-nm post-Golgi vesicles that are normally destined to melanosomes.

185 lead to metastasis and be a marker for cells destined to metastasize.

186 recursor cells arising in the lateral somite destined to migrate to and populate the limb musculature

187 he myotome, and later in myotomal precursors destined to migrate towards their final destination, for

188 yopherinbeta1 transport-receptor and cargoes destined to nuclear import.

189 ted neurons, some of which are GABAergic and destined to occupy superior colliculus.

190 ve as alternative ligands for the metal ions destined to occupy the A and B catalytic sites.

191 dymal cells continuously produce new neurons destined to olfactory bulb.

192 We exchanged neural crest cells destined to participate in beak morphogenesis between tw

193 re consistent with the hypothesis that SHBG, destined to participate in signaling at the cell membran

194 ompared the outcome of paired donor kidneys, destined to patients who had ESRD more than 2 years comp

195 of KLRG1(hi) CD8+ T cells, which are usually destined to perish during contraction, without inducing

196 E) 80 and E90 to block the division of cells destined to populate the superficial cortical layers, be

197 These data indicate that GOLD36 is a protein destined to post-ER compartments and suggest that its ex

198 18 had big size and oval form so it could be destined to potato chips industry.

199 show that Neurod1-expressing RPCs, which are destined to produce amacrine and photoreceptor cells, ca

200 ppropriate gene expression occurred in cells destined to produce either cell type and caused correspo

201 T cells destined to produce IL-2 required prolonged interactions

202 Progenitors destined to produce LAMP neurons, however, will differen

203 ation of the GGTase-I-encoding gene in cells destined to produce lung tumors driven by oncogenic K-Ra

204 an essential component of a genetic program destined to produce the cellular complexity of the mamma

205 adaptive rather than an unstable physiology destined to progress to irreversible injury.

206 esions and approximately 40% of all patients destined to progress to proteinuria are normoalbuminuric

207 Nano-enabled products are ultimately destined to reach end-of-life with an important fraction

208 vascular cells selectively in a vascular bed destined to regress.

209 then increased specifically in the allograft destined to rejection.

210 However, patients are destined to relapse and few, if any, are cured.

211 disease focuses on the detection of patients destined to relapse despite appearing to be in clinical

212 ods have been studied that identify patients destined to relapse.

213 D1, responds well to initial therapy but is destined to relapse.

214 template DNA are segregated to the daughter destined to remain a stem cell, thus insuring lifetime g

215 that give rise to neurons and those that are destined to remain as nervous system outsiders.

216 teeth are required and antagonism in regions destined to remain edentulous.

217 that become mineralized compared to collagen destined to remain nonmineralized.

218 ancreatography and endoscopic ultrasound are destined to replace endoscopic retrograde cholangiopancr

219 ve was to learn whether they influence cells destined to replenish the immune system.

220 Many proteins that are destined to reside within the lumen of the peroxisome co

221 Connectivity of males destined to rise did not change over time but increased

222 that the number of DCD kidney transplants is destined to rise in the UK, we believe that ATG is a val

223 nge the notion that CD8(+) and CD8(-) DC are destined to selectively induce Th1 or Th2 responses, res

224 wn, this is a rapidly emerging field that is destined to suggest novel antiviral therapies.

225 ing actions of these genes in cells that are destined to survive.

226 bed ribbon around midcell where septation is destined to take place.

227 ow distinct migration pathways of POMC cells destined to the anterior and intermediate lobes.

228 e fission of transport carriers specifically destined to the cell surface.

229 e fission of transport carriers specifically destined to the cell surface.

230 rk, regulating fission of transport carriers destined to the cell surface.

231 ed protein (GET) pathway selects TA proteins destined to the endoplasmic reticulum (ER) utilizing dis

232 lyzes the transfer of tail-anchored proteins destined to the endoplasmic reticulum from Sgt2 to the c

233 upling of transport and translation of mRNAs destined to the remote areas such as axons.

234 ate that a subset of BiP-ligand complexes is destined to the vacuole and differs from those likely to

235 Their target proteins are destined to transit cellular membranes during their bios

236 Most proteins destined to travel the TTSS pathway possess at least two

237 Proteins destined to travel this secretion pathway are targeted t

238 characterizing future cell therapy products destined to treat endothelial dysfunctions.

239 ent NTP:P(i) was higher in patients who were destined to undergo a durable event-free survival compar

240 y, that p53 accumulates in nuclei of neurons destined to undergo apoptosis.

241 lly end-stage cells trapped in the liver and destined to undergo apoptotic cell death in that organ.

242 s, while at the same time making these cells destined to undergo apoptotic cell death.

243 dent defenses and to trap pathogens in cells destined to undergo hypersensitive cell death, (ii) as a

244 minority of ulcerative colitis (UC) patients destined to undergo neoplastic progression.

245 of caspase-3 are administered to motoneurons destined to undergo PCD, decreased levels of APP protein

246 e root cap, atao1 expression occurs in cells destined to undergo programmed cell death.

247 her hibernating myocardium is adaptive or is destined to undergo progressive irreversible injury.

248 this gene to determine if axotomized neurons destined to undergo retrograde death could be rescued.

249 ells, those daughters of stem cells that are destined to withdraw from the cell cycle and terminally