ライフサイエンスコーパス: deterioration

1 waitlist mortality (or removal for clinical deterioration).

2 usness level, and other evidence of clinical deterioration.

3 ergoing structural remodeling and functional deterioration.

4 more reliable screening of vestibular system deterioration.

5 itis, were severe and associated with visual deterioration.

6 through which these compounds mediate oocyte deterioration.

7 no domains indicating clinically meaningful deterioration.

8 mosome that protect the chromosome ends from deterioration.

9 ng critical periods of risk for mental state deterioration.

10 itive impairment and aging-related cognitive deterioration.

11 xercise capacity may be a marker of clinical deterioration.

12 one patient (2%) had general physical health deterioration.

13 igator's choice led to clinically meaningful deterioration.

14 ficient or no IS may contribute to allograft deterioration.

15 al global feedstock, but is prone to aerobic deterioration.

16 sual care patients with lung cancer reported deterioration.

17 ges and frequently leads to a rapid clinical deterioration.

18 herapies to specific criteria of physiologic deterioration.

19 qual to 10 minutes defined acute physiologic deterioration.

20 transplant rates, or delisting for death, or deterioration.

21 iable risk factors were associated with HRQL deterioration.

22 istically significant predictor of cognitive deterioration.

23 dose PDT before they have significant visual deterioration.

24 that met face validity for acute physiologic deterioration.

25 e strategy for treating age-related neuronal deterioration.

26 e systems, are very susceptible to microbial deterioration.

27 myloid burden, although preventing cognitive deterioration.

28 carries the risk of postoperative cognitive deterioration.

29 cal care resources to patients with clinical deterioration.

30 o dendritic processes and associated synapse deterioration.

31 entricular adverse remodeling and functional deterioration.

32 improve clonal selection against age related deterioration.

33 syndrome led to pulmonary vascular mechanics deterioration.

34 op productivity, and increases environmental deterioration(1,2).

35 's choice group showed clinically meaningful deterioration (10 points or more) at week 15 (change fro

36 erosis were vulnerable to early neurological deterioration (19.4%), and the top two white matter hype

37 prevalent feature of aging is mitochondrial deterioration [3].

38 ned a murine threshold for acute physiologic deterioration after cecal ligation and puncture that has

39 firm that some patients experience cognitive deterioration after TAVI.

40 associated with disease) and general health deterioration after the biotic disturbance, rather than

41 wer rate of functional, motor, and cognitive deterioration (all p < 0.001), independent of mutant HTT

42 ncluded in the time to clinically meaningful deterioration analyses.

43 rate of death or removal because of clinical deterioration and a 42% (95% CI, 10-85%) higher rate of

44 ary hypertension is associated with clinical deterioration and a substantially increased mortality ri

45 ed at an early stage to help prevent further deterioration and buy time for potential spontaneous rec

46 ree remission, with prevention of functional deterioration and clinically relevant radiographic damag

47 op infantile-onset of progressive neurologic deterioration and death by 2 years of age, whereas other

48 t heart failure have a high risk of clinical deterioration and death during or soon after endotrachea

49 nd is among the events that predict clinical deterioration and death.

50 rther helps to determine risk of age-related deterioration and death.

51 ay reduce the risk of experiencing cognitive deterioration and dementia in later-life.

52 ociated with an increased risk for cognitive deterioration and dementia.

53 Deterioration and extreme nonresponse and, similarly, su

54 with PD who experienced signs of end-of-dose deterioration and had a mean total awake off-time (state

55 wn to have good predictive value for patient deterioration and have been shown to improve patient out

56 the relationship between subjective economic deterioration and housing damage due to the disaster and

57 estimated the impact of subjective economic deterioration and housing damage due to the disaster on

58 Subjective economic deterioration and housing damage due to the disaster wer

59 ins are particularly important because their deterioration and misfolding/aggregation are associated

60 these changes are associated with functional deterioration and neurodegenerative disease.

61 oung adults and cause progressive neurologic deterioration and premature death.

62 men with botulism had progressive neurologic deterioration and respiratory failure, requiring intensi

63 p between baseline and rates of visual field deterioration and the probability of vision-related disa

64 s, it is susceptible to disease, postharvest deterioration and the roots contain low nutritional cont

65 tion of the LFU ultimately results in tissue deterioration and the symptoms of DED.

66 d prevent hypoxia and secondary neurological deterioration and thus has the potential to improve reco

67 lowed 24H of preservation without functional deterioration and was superior to both RBC and buffered

68 rotocol as a significant clinical or airflow deterioration), and the secondary outcome was asthma exa

69 months; 16.5% experienced early neurological deterioration, and 3.3% recurrent stroke.

70 ble outcomes, hematoma expansion, neurologic deterioration, and severe hypotension were not significa

71 Relevantly, the deterioration appears strongly associated with the forma

72 i that protect against age-related cognitive deterioration arising from neurodegenerative disease or

73 Structural valve deterioration at 24 months did not occur in either group

74 There was less cognitive deterioration at 3 months after SRS alone (40/63 patient

75 [95% CI 0.35-0.63]; p<0.0001), and cognitive deterioration at 6 months was less frequent in patients

76 assess the pattern of threshold sensitivity deterioration at each VF location as a function of time.

77 ET/computed tomography because of radiologic deterioration at follow-up MR imaging between 2006 and 2

78 ent presenting with progressive neurological deterioration attributed to JCPyV encephalopathy.

79 arker discovery to predict or diagnose graft deterioration before it becomes irreversible.

80 to determine the composition and hydrolytic deterioration behavior of rice bran fractions which were

81 inal degeneration and progressive neurologic deterioration, but have recently also been identified in

82 r whether this represents acclimatisation or deterioration, but it does appear to be regulated, with

83 velocity index, and evidence of hemodynamic deterioration by reintervention, adverse hemodynamics, o

84 escalation of care in the setting of patient deterioration can prevent further harm.

85 Nevertheless, environmental deterioration can reshape population interactions, this

86 and in detection of adulteration as well as deterioration caused by external factors.

87 valuated different variable combinations and deterioration criteria to select the most robust algorit

88 The primary end point was cognitive deterioration (decline >1 SD from baseline on at least 1

89 ncrease by 5-10% accounting for the observed deterioration, depending on the country and its share of

90 sh an endpoint capturing clinically relevant deteriorations (diary events) that, when combined with s

91 ithelium of the aging female undergoes major deterioration, driven by intestinal stem cell (ISC) divi

92 P increased the risk of O2 entry and aerobic deterioration during feed-out phase.

93 s from heat induced disruption and oxidative deterioration during spray drying was assessed.

94 faunal changes are associated with climatic deterioration during the Eocene-Oligocene transition (EO

95 tudy asks which index can detect significant deterioration earliest, for a fixed specificity.

96 linic who developed progressive neurological deterioration (encephalopathy) and we wished to investig

97 Clinically relevant deterioration for some symptoms was observed at week 10,

98 The co-primary endpoints were cognitive-deterioration-free survival and overall survival, and an

99 Cognitive-deterioration-free survival was longer in patients assig

100 causes of heart failure, the full process of deterioration from a healthy to a failing heart yet rema

101 ), and less likely to experience a sustained deterioration from normoalbuminuria to microalbuminuria

102 gnificantly less proportion of patients with deterioration (>/=5 points decrease) of both KCCQ scores

103 ndary outcome measure was time to definitive deterioration (>/=7 points) in FACT-G total score.

104 actors associated with significant cognitive deterioration (>10% decline).

105 One patient, who had had rapid neurologic deterioration, had died from disease progression.

106 5 years of a series, MD detected significant deterioration in 138 eyes, vs 104 for VFI (P = .0013) an

107 We present an example of severe clinical deterioration in a patient with HCM due to superimposed

108 4/KIF1A as a key regulator of neural circuit deterioration in aging C. elegans.

109 e was a reduced risk of an exacerbation with deterioration in asthma symptoms (HR, 0.72 [95% CI, 0.49

110 Secondary outcomes were deterioration in asthma symptoms, change in allergen-spe

111 that for males, this was principally due to deterioration in barrier defences, whereas for females s

112 sleep, and attenuates age- and diet-induced deterioration in cardiac performance.

113 America and Europe, but a contrasting sharp deterioration in developing regions of Asia.

114 ll dysfunction to progressive beta-cell mass deterioration in diabetes.

115 functional assessments for detecting muscle deterioration in DMD.

116 mpromise myofiber integrity and drive muscle deterioration in Duchenne muscular dystrophy (DMD).

117 e responsiveness to Nexvax2 peptides without deterioration in duodenal histology.

118 tating a change in anticancer therapy and/or deterioration in Eastern Cooperative Group performance s

119 Median time to definitive deterioration in FACT-G total score was 11.27 months (95

120 implications for the prevention of skeletal deterioration in health and disease.

121 However, follow-up CT, performed after deterioration in his general condition, showed jejunal d

122 d Cu carboxylates (soaps) has caused visible deterioration in hundreds of oil paintings dating from t

123 Deterioration in its ecohydrological system has received

124 devastating disease with rapidly progressive deterioration in kidney function, which, histologically,

125 Intravenous MSCs eliminated the progressive deterioration in LV end-diastolic volume and LV end-syst

126 cardial infarction attenuate the progressive deterioration in LV function and adverse remodeling in m

127 MAC (MAC-PP) and its impact on radiographic deterioration in MAC-LD.

128 c immunosuppressive therapy may experience a deterioration in mental health-related quality of life.

129 ession of beta-cell dysfunction and glycemic deterioration in models of T1D.

130 INTERPRETATION: EIM detects deterioration in muscles of both younger and older boys

131 increase in arterial LPS concentrations and deterioration in neutrophil phagocytosis.

132 ry nerve responses showed significantly less deterioration in NO-GC1 KO and NO-GC2 KO mice after nois

133 on MRI are associated with SVD and cognitive deterioration in older individuals is unknown.

134 nctional hub load and postsurgical cognitive deterioration in patients undergoing lesion resection.

135 associated with proteinuria and rapid renal deterioration in patients with CKD.

136 therapy, resulting in irreversible clinical deterioration in patients with MMP.

137 Pain is correlated with a deterioration in patients' quality of life and increased

138 ction, septic shock, encephalopathy, general deterioration in physical health, abnormal hepatic funct

139 se effects from recent clozapine exposure or deterioration in physical or mental health precipitated

140 l policies but a penalty for a region with a deterioration in PM2.5 pollution.

141 irmed the presence of a widespread cognitive deterioration in PP-MS patients, with main involvement o

142 No deterioration in protein amount or quality was observed

143 egardless of assigned treatment, 33.3% had a deterioration in QoL, 9.2% had no change, 9.2% had a sma

144 dical treatment might reflect the effects of deterioration in quality of care during economic recessi

145 n) and deteriorating PS were associated with deterioration in quality-of-life parameters (P < .001).

146 vein thrombosis (16 mg/day) and unexplained deterioration in renal function in follow-up (patients w

147 Although chronic deterioration in renal function is frequently seen after

148 These changes were paralleled by a marked deterioration in rennet coagulability, higher ethanol st

149 m layer, leading to a progressive functional deterioration in retinal light responses.

150 Deterioration in SARA was associated with younger age of

151 d in long-term memory acquisition and in its deterioration in senescence.

152 There was a trend to deterioration in sexual function score (mean decrease, 4

153 ial therapeutic approach to prevent glycemic deterioration in T1D.

154 fidence interval -0.56 to 0.15) with further deterioration in T2DM (B=-0.61 [-0.97 to -0.25]) versus

155 rediabetes (B=-46 [-163 to 72]) with further deterioration in T2DM (B=-184 [-297 to -71]) versus norm

156 ascular neurologists) was RCVE: neurological deterioration in the absence of a medical explanation or

157 That year marks the onset of a rapid deterioration in the capacity of the GICs firn to refree

158 The patient had progressive neurologic deterioration in the first month of life.

159 should be preferred for imaging in case of a deterioration in the general condition and laboratory fi

160 Failure to detect clinical deterioration in the hospital is common and associated w

161 cale, in contrast to a clinically meaningful deterioration in the investigator's choice group (7.3 vs

162 The times to detect significant deterioration in the longitudinal cohort were compared u

163 cotinine (200 ng/ml detection limit) without deterioration in the other 2.

164 f hospitalization, when a sudden and serious deterioration in the patient's condition was observed du

165 Fewer pembrolizumab-treated patients had deterioration in the QLQ-LC13 composite endpoint than di

166 t ventricular (RV) apical pacing may lead to deterioration in ventricular function and an increased r

167 udy; this loss was associated with a sizable deterioration in VSF.

168 n infection mortality are causally driven by deteriorations in canonical systemic immune processes is

169 This might contribute to early deteriorations in hepatic function, which in turn result

170 Wellbore cement deterioration is critical for wellbore integrity and the

171 cessary testing, while ensuring that patient deterioration is identified in a timely manner.

172 borhood physical disorder-a measure of urban deterioration-is thought to encourage crime and high-ris

173 ningitis (CM) frequently experience clinical deterioration, known as cryptococcosis-associated immune

174 However, inflammation and structural deterioration limit transplant durability.

175 inically marked by slowly progressive visual deterioration, lymphomatous ONI is rare and characterize

176 lindness is nonlinear and that its course of deterioration may change with the course of disease.

177 of specific symptoms related to neurological deterioration necessitate an appropriate and early palli

178 Chiasm involvement and severe vision deterioration occurred 3 months later.

179 , small, moderate, and large improvement, or deterioration of any magnitude.

180 he present study was to estimate the quality deterioration of apple fillings during storage.

181 that prevented the age-dependent functional deterioration of ASH.

182 s a suitable clinical rating scale to detect deterioration of ataxia symptoms over time; ADL is an ap

183 Moreover, deterioration of axoglial junctions of the spinal cord w

184 This indicates that deterioration of axons and myelin after axotomy are mech

185 YGLOW is a useful tool for investigating the deterioration of behavioural and molecular rhythms in ag

186 ary beta-cell dysfunction to the progressive deterioration of beta-cell mass in diabetes.

187 e first direct evidence for a diet-dependent deterioration of Ca(2+) homeostasis in POMC neurons duri

188 Thus, these findings indicate that there is deterioration of CA1 volume in persistently symptomatic

189 the pathophysiological mechanisms underlying deterioration of cardiac function in HFpEF are poorly un

190 ar edema that is closely associated with the deterioration of central vision.

191 mal storage disease resulting in progressive deterioration of cognitive acquisition after age 2-4 yea

192 Age-related deterioration of cognitive capacity in humans compromise

193 rative disorder characterized by progressive deterioration of cognitive function.

194 Deterioration of coral health and associated change in t

195 E imaging are good predictors of age-related deterioration of cortical bone structure and are potenti

196 to introduce a new predictor for age-related deterioration of cortical bone structure.

197 A similar deterioration of disease was recapitulated in in vivo mi

198 There was a slight insignificant deterioration of EPIC urinary symptom score (mean increa

199 Deterioration of erectile dysfunction scores was not ass

200 t statistics, we showed associations between deterioration of erectile function and lesion sites in t

201 ormed in 30 patients; clinically, those with deterioration of exercise capacity had poorer outcomes.

202 of various etiologies and usually caused by deterioration of glomerular filtration barrier integrity

203 to obesity-associated insulin resistance and deterioration of glucose metabolism via altered neurocir

204 7(-/-) mice show impaired insulin secretion, deterioration of glucose tolerance with either aging and

205 ced allograft damage and prevented the rapid deterioration of graft function on day 3.

206 Hence, a possible deterioration of insulin secretion capacity in patients

207 lin content and beta-cell mass and prevented deterioration of islet organization.

208 ausal relationship between pro-ENK level and deterioration of kidney function over time.

209 ation are worse if intervention occurs after deterioration of left ventricular size and function.

210 RYGB are more susceptible to early transient deterioration of liver function than after SG.

211 disease, only the LCI identified significant deterioration of lung function in CF over time.

212 on with low-dose A/X31 H3N2 led to prolonged deterioration of lung function, aggravated mucus product

213 on fraction (LVEF) remain at risk for future deterioration of LVEF.

214 care (9.2%), and 2 were readmitted owing to deterioration of medical conditions (1.2%).

215 ere not caused by suboptimal medical care or deterioration of medical conditions but by confounding i

216 Both patients experienced deterioration of mental status, respiratory depression,

217 The deterioration of mitophagy has been hypothesized to unde

218 ns during stem cell transplantation included deterioration of motor and bladder functions (n = 12) as

219 ay alleviate motor symptoms and/or delay the deterioration of motor function in movement disorders by

220 ion was achieved in all eight survivors, but deterioration of motor function occurred in the majority

221 95% CI, 1.06-2.59; p = 0.03) and a marginal deterioration of neurologic outcome (risk ratio, 0.90; 9

222 Results suggest deterioration of NOx unit emissions for Euro 2 and Euro

223 atigue and is associated with a time-related deterioration of objective performance, the degree of wh

224 Nivolumab delayed time to deterioration of patient-reported quality-of-life outcom

225 argets of P. gingivalis, contributing to the deterioration of periodontal lesion through an increased

226 tion, whereas conditional helping leads to a deterioration of recognition ability.

227 tributed to a high rate of mortality and the deterioration of renal function (both log-rank tests, P

228 nnumerous fluid-filled cysts and progressive deterioration of renal function.

229 aracterized by rapid (<2 wk) and progressive deterioration of renal function.

230 ency for hyperkalemia, though none had rapid deterioration of renal function.

231 iological mechanisms involved in the dynamic deterioration of secondary MR during exercise, its funct

232 yed tumorigenesis and attenuated age-related deterioration of several organs without apparent side ef

233 loss of memory functions, but also prominent deterioration of sleep physiology, which is already evid

234 eficits in grid cell firing and underlie the deterioration of spatial cognition seen in human AD.

235 The risk of waitlist death or deterioration of status 1A inotrope candidates relative

236 This work aimed to control the fungal deterioration of strawberry jams.

237 t changes in neural activity consistent with deterioration of task-related networks over time.

238 the mechanisms underlying the age-dependent deterioration of tendon function remains very limited.

239 reconcentrate up to 100 mL of sample without deterioration of the analytical signal.

240 GHS)/quality-of-life (QOL) score and time to deterioration of the composite of cough, chest pain, and

241 simulations consistently evidence a dramatic deterioration of the crystals' surface, with potentially

242 Unlike the invariably progressive deterioration of the disease, 8 months after liver trans

243 emonstrate its robustness in suppressing the deterioration of the electrode/electrolyte interface dur

244 set progressive hearing loss associated with deterioration of the hair bundle structure, leading to t

245 cating environment can produce a significant deterioration of the lacrimal function unit in female SS

246 in the overall work function corresponds to deterioration of the mechanical strength of the steel.

247 nalysis indicates widespread microstructural deterioration of the normal-appearing white matter in no

248 ness and composition exhibited a significant deterioration of the signal after identical treatment.

249 ts along with the enlargement of kidneys and deterioration of their function, eventually leading to r

250 How to suppress the performance deterioration of thermoelectric materials in the intrins

251 Our work demonstrates that the performance deterioration of thermoelectric materials in the intrins

252 ually correct, the failures that lead to the deterioration of this important cell population.SIGNIFIC

253 undation of relational representation, and a deterioration of this mechanism is responsible for the a

254 r, micro-computed tomography revealed robust deterioration of trabecular bone volume by both subsets,

255 Reintervention was caused by structural deterioration of transcatheter heart valves in only 5 pa

256 The ongoing deterioration of wetland ecosystems in many shallow estu

257 The deterioration of white matter fiber tracts associated wi

258 The deterioration of whole blood ex vivo represents a logist

259 There is a group which displays behavioural deterioration on antipsychotic reduction that prevents d

260 ificant differences were observed in time to deterioration on the European Organization for Research

261 different techniques for detecting clinical deterioration on the wards in a large, multicenter datab

262 ount (one [2%]), and general physical health deterioration (one [2%]).

263 er, PPCM patients show either a fast cardiac deterioration or complete recovery.

264 Patients with deterioration or superior response had lower pretreatmen

265 y surgery or radiotherapy because of disease deterioration, or death from any cause, assessed in the

266 eas some contribute to progressive cognitive deterioration, others lower the level of cognition but e

267 ined by the rapid post-harvest physiological deterioration (PPD) of its roots that occurs within 24-7

268 The unprecedented deterioration rate of the environmental quality due to r

269 ion rates 48.7% and 45.5%, respectively, and deterioration rates 12.8% and 10.4%, respectively (P = .

270 in of antibiotic-associated gastrointestinal deterioration remains elusive and no specific infectious

271 uces retinal VSMC loss and basement membrane deterioration resulting in vascular regression and retin

272 The nine CMS subjects with neurological deterioration showed diffuse cerebral edema on imaging a

273 MD detected significant deterioration sooner than VFI or PSD.

274 its, but due to their strong odors and rapid deterioration, their application in food formulations is

275 icant variability in the time to reach acute deterioration threshold across mice, ranging from 339 to

276 partment, two groups of patients with recent deterioration to bilateral visual acuity less than Snell

277 Secondary outcomes included clinical deterioration (transfer to ICU, initiation of vasopresso

278 weeks until disease progression and clinical deterioration, unacceptable toxicity, or other protocol-

279 l outcomes after TBI can show improvement or deterioration up to two decades after injury, and rates

280 After clinical deterioration using meropenem monotherapy, treatment suc

281 nd factors associated with valve hemodynamic deterioration (VHD) after transcatheter aortic valve rep

282 t change in renal elasticity for rapid renal deterioration was 0.928 (95% CI, 0.864-0.997; P = 0.042)

283 1 mm change in renal length for rapid renal deterioration was 1.022 (95% CI, 0.994-1.050; P = 0.125)

284 Median time to clinically meaningful deterioration was analysed by Kaplan-Meier methods.

285 consanguineous Bedouin kindred: neurological deterioration was evident as of early age, progressing i

286 Cognitive deterioration was found in 29 patients (12.7%).

287 Time to deterioration was longer with pembrolizumab than with ch

288 Median time to deterioration was significantly longer with nivolumab ve

289 Endpoint visual status (remission or deterioration) was determined for each patient based on

290 The levels of further corn oil deterioration were 2.1 w/w of calcium hydroxide concentr

291 nd their contributions to indoor air quality deterioration were examined by collecting PM2.5 inside a

292 n addition, no significant colour or texture deterioration were found on produce samples treated with

293 suggestive of valve thrombosis or structural deterioration, were rare in this protocol-driven databas

294 to a polymer group, displayed a significant deterioration, which might be attributed to biologically

295 0/60, visual field showed severe progressive deterioration with a central and supero-nasal field remn

296 ge 35, and the rate of fractional anisotropy deterioration with age was constant and best modeled wit

297 a significantly faster rate of white matter deterioration with age.

298 The median time to detect significant deterioration with MD was 7.3 years (95% confidence inte

299 5% of test-retest series showed significant deterioration with P < CritIndex, using artificial "test

300 u formation spurred the global environmental deterioration, yet this view is supported by patchy foss