ライフサイエンスコーパス: deubiquitination

1 SP7 and p53 and attenuates USP7-mediated p53 deubiquitination.

2 ng proteasome activity even when inactive in deubiquitination.

3 yed TNF receptor-associated factor 6 (TRAF6) deubiquitination.

4 transcriptional regulator mediating histone deubiquitination.

5 UBPY also bind STAM2 SH3 to facilitate EGFR deubiquitination.

6 e formation suggest allosteric regulation of deubiquitination.

7 the diubiquitin substrate in USP2-catalyzed deubiquitination.

8 scriptionally prime NLRP3 by stimulating its deubiquitination.

9 istone acetylation and Ubp8-mediated histone deubiquitination.

10 the enzymes involved in MITF ubiquitination/deubiquitination.

11 tation activity mediates degradation-coupled deubiquitination.

12 osis of several receptors by virtue of their deubiquitination.

13 cifically directs USP1-UAF1 complex for PCNA deubiquitination.

14 al strategy used to achieve linkage-specific deubiquitination.

15 stem or be reactivated by USP-33/20-mediated deubiquitination.

16 ereas overexpression of USP14 promotes CXCR4 deubiquitination.

17 known about counter mechanisms for receptor deubiquitination.

18 m to delay ILV budding while cargoes undergo deubiquitination.

19 a dimeric enzyme, which can be reversed upon deubiquitination.

20 change in dimer conformation persists until deubiquitination.

21 ry mechanism for DUB activity involving auto-deubiquitination.

22 s, competition by processive substrates, and deubiquitination.

23 through the processes of ubiquitination and deubiquitination.

24 iquitin hydrolase HAUSP can stabilize p53 by deubiquitination.

25 VB sorting and is required for cargo protein deubiquitination.

26 hin the BRCA2 pathway independently of BRCA2 deubiquitination.

27 ion prolongs D2 half-life and activity by D2 deubiquitination.

28 example of enzyme activity being restored by deubiquitination.

29 gion, which is important for conjugation and deubiquitination.

30 he proteasome was reduced by USP14-dependent deubiquitination.

31 or to lysosomal degradation and promotes its deubiquitination.

32 emical coupling of substrate degradation and deubiquitination.

33 gatively regulate autophagy by promoting K63 deubiquitination.

34 ated-ubiquitin (Ub) is protected from active deubiquitination.

35 perative stable ternary complex required for deubiquitination.

36 functional role for ASXL3 in PR-DUB mediated deubiquitination.

37 s are required for ubiquitin binding and H2A deubiquitination.

38 ly regulated by cycles of ubiquitination and deubiquitination.

39 interference leads to the suppression of p53 deubiquitination.

40 re and function independently of its role in deubiquitination.

41 ite of ILV budding while the cargoes undergo deubiquitination.

42 ex mechanism of step-wise ubiquitination and deubiquitination activities that allows contemporaneous

43 nd its ubiquitination disappears, suggesting deubiquitination activity at the cell surface.

44 tion coactivator that contains a histone H2B deubiquitination activity mediated by its Ubp8 subunit.

45 ition and the H2A(Y57F) mutation enhance H2B deubiquitination activity of the Spt-Ada-Gcn5 acetyltran

46 active-site mutant of UBP3, indicating that deubiquitination activity of UBP3/UBP4 is required.

47 hat the overexpression of UCHL1, but not its deubiquitination activity-deficient mutant (UCHL1 C90S),

48 12 and USP46 and is required for the histone deubiquitination activity.

49 hose degradation critically depends on UCH37 deubiquitination activity.

50 terminal domains of EBNA3C contribute to the deubiquitination activity.

51 P7 or USP10 with high affinity and inhibited deubiquitination activity.

52 diatric leukaemia, which result in decreased deubiquitination activity.

53 To prevent deubiquitination after lysis or the copurification of in

54 ome contribute to Lys-48- and Lys-63-linkage deubiquitination, albeit the inhibitory extents are diff

55 ion to ubiquitin, and enzyme reactivation by deubiquitination, allowing tight control of thyroid horm

56 This commitment step precedes substrate deubiquitination and allows for selection of ubiquitinat

57 ism by which p53 can be stabilized by direct deubiquitination and also imply that HAUSP might functio

58 eads to ATPase stimulation, thereby coupling deubiquitination and ATP hydrolysis.

59 protein degradation by catalyzing substrate deubiquitination and by poorly understood allosteric act

60 recruits BAP1 to DNA, promotes local histone deubiquitination and causes changes in target gene activ

61 regulator of NLRP3 activity by promoting its deubiquitination and characterizing NLRP3 as a substrate

62 eal an unexpected coupling between substrate deubiquitination and degradation and suggest a unifying

63 ase subunit of the proteasome, which couples deubiquitination and degradation of proteasome substrate

64 om this novel enterovirus also showed strong deubiquitination and deISGylation activities and demonst

65 transcriptional gene repression via histone deubiquitination and demethylation.

66 rupts UAF1/FANCI binding and inhibits FANCD2 deubiquitination and DNA repair.

67 an unanticipated connection between protein deubiquitination and endomembrane protein trafficking in

68 a histone H2A deubiquitinase, regulates H2A deubiquitination and gene expression in ESCs, and import

69 ranscriptional activation of FLC through H2B deubiquitination and is consistent with a model in which

70 The mechanisms of PAR(2) deubiquitination and its importance in trafficking and s

71 ibition of HAUSP then led to the loss of p53 deubiquitination and its stabilization in response to ce

72 21 stabilizes FOXP3 protein by mediating its deubiquitination and maintains the expression of Treg si

73 disrupt catalytic activation of Doa4 impair deubiquitination and sorting of MVB cargo proteins and l

74 verexpression of DOA4 restores cargo protein deubiquitination and sorting via the MVB pathway and rev

75 SP37 formed a complex with p27, promoted its deubiquitination and stabilization and blocked cell prol

76 M1 and deubiquitinating enzyme USP5, thereby deubiquitination and stabilization of FoxM1.

77 ifically, we demonstrated that USP7 promotes deubiquitination and stabilization of PHF8, leading to t

78 tion antagonizes this activity, resulting in deubiquitination and stabilization of SMURF1.

79 We also demonstrated that USP2a-dependent deubiquitination and stabilization of the CRY1 protein o

80 SAGA complex regulates telomere function via deubiquitination and stabilization of the telomere repea

81 une regulation that involves OTUD7B-mediated deubiquitination and stabilization of TRAF3.

82 cytokine tumor necrosis factor (TNF) induces deubiquitination and stabilization, leading to ASK1 acti

83 interacted with tankyrases to promote their deubiquitination and stabilization.

84 This switch is rate-limiting for deubiquitination and strongly accelerated by mechanical

85 cts with N-Myc, and HAUSP expression induces deubiquitination and subsequent stabilization of N-Myc.

86 This coupling between deubiquitination and substrate degradation is ensured by

87 -M regulates Hox gene expression through H2A deubiquitination and that blocking the function of Ubp-M

88 inactivation, the enzyme(s) involved in H2A deubiquitination and the function of H2A deubiquitinatio

89 tion by coordinating histone acetylation and deubiquitination, and destabilizing the association of l

90 suited to coordinate substrate recruitment, deubiquitination, and movement toward the catalytic core

91 lled by a balance between ubiquitination and deubiquitination, and that Cezanne is a key regulator of

92 ated by a balance between ubiquitination and deubiquitination, and that disruption of this balance ca

93 dies now indicate that basal ubiquitination, deubiquitination, and transubiquitination of certain GPC

94 ede1Delta indicates that ubiquitination and deubiquitination are likely to regulate additional compo

95 H2A deubiquitination and the function of H2A deubiquitination are not known.

96 mechanisms responsible for their reversible deubiquitination are still poorly understood.

97 licate DNA-damage-induced ubiquitination and deubiquitination as a major regulator of the DNA-damage

98 Together, our findings identify deubiquitination as a means to regulate BRCA2 function a

99 experimental analyses identified continuous deubiquitination as a prerequisite for maximal substrate

100 Zhang et al. have identified deubiquitination as a signal amplifier.

101 erefore, this study identifies Usp16 and H2A deubiquitination as critical regulators of ESC gene expr

102 chains may not require direct ubiquitination/deubiquitination as is required for proteasome-mediated

103 seem to depend on its polyubiquitination and deubiquitination; as well, the contrasting effects of PS

104 quitination of IRF7 in vivo, but an in vitro deubiquitination assay with purified constituents shows

105 deubiquitinates XPC-ubiquitin conjugates in deubiquitination assays in vitro.

106 hat interacts with Cdu1 and is stabilized by deubiquitination at the chlamydial inclusion.

107 mechanism to prevent the onset of ILV cargo deubiquitination at the initiation of ESCRT-III complex

108 roteasome substrates, the molecular basis of deubiquitination at the proteasome and its relation to s

109 nd reveal a model in which a phosphorylation-deubiquitination axis dynamically regulates RAP80-BRCA1

110 Ets-1 deubiquitination blocks its proteasomal destruction and

111 1 in coordinating the timing and location of deubiquitination by Doa4 in the MVB pathway.

112 ress stimulates Cry1 phosphorylation and its deubiquitination by Herpes virus associated ubiquitin-sp

113 In turn, Bro1 directly stimulates deubiquitination by interacting with a YPxL motif in the

114 Deubiquitination by Rpn11 and ubiquitin unfolding by the

115 cIAP1 rather than to stimulation of IKKgamma deubiquitination by the deubiquitinases A20 and CYLD (cy

116 Ubiquitination by the E3 ligase Nedd4 and deubiquitination by the deubiquitinases USP20 and USP33

117 Deubiquitination by the Fat facets protein - a regulator

118 Deubiquitination by ubiquitin-specific protease 2a and A

119 Until now, whether deubiquitination by ubiquitin-specific proteases can reg

120 Further studies reveal that H2A deubiquitination by Ubp-M is a prerequisite for subseque

121 Thus deubiquitination by Ubp15 counteracts APC activity towar

122 Deubiquitination by Uch37 is activated by proteasomal bi

123 K48 deubiquitination by USP14 is known to inhibit UPS.

124 e evicted from DNA during transcription, for deubiquitination by Usp15.

125 mic balance of ubiquitination by the APC and deubiquitination by USP44 contributes to the generation

126 ific deubiquitinase and demonstrate that H2B deubiquitination by USP49 is required for efficient cotr

127 nd reveal a model in which a phosphorylation-deubiquitination cascade dynamically regulates the BRCA2

128 ion has repercussions for ubiquitination and deubiquitination cascades beyond Parkin activation and m

129 y USP2A, USP4, or USP7, other members of the deubiquitination catalytic family.

130 However, whether active deubiquitination co-regulates ubH2A levels in ESCs and d

131 Pharmacological inhibition of NLRP3 deubiquitination completely blocked NLRP3 activation in

132 t3Delta, suppressors in the SWR1 and the H2B deubiquitination complexes show strong functional simila

133 etrograde transport or in the ubiquitination-deubiquitination complexes, are promising candidates as

134 tein involved in mRNA export and histone H2B deubiquitination, contains two introns; non-canonical se

135 Our findings suggest that regulation of deubiquitination could be exploited therapeutically in c

136 telomeres is controlled by a ubiquitination/deubiquitination cycle depending on opposing ubiquitin l

137 ropose that ubiquitination or ubiquitination/deubiquitination cycling specifically regulates later pr

138 the temperature sensitivity and histone H2B deubiquitination defects observed in sus1Delta cells are

139 are regulated and how proteolysis, substrate deubiquitination, degradation, and ATP hydrolysis are co

140 (BMAL1) and reducing its ubiquitylation in a deubiquitination-dependent manner.

141 umoniae-induced NFAT signaling pathway via a deubiquitination-dependent mechanism.

142 e inhibition of TRAF6 and TRAF7 likely via a deubiquitination-dependent mechanism.

143 nation of TBK1-IKKi independently of the A20 deubiquitination domain.

144 , TBP binding, histone acetylation (HAT) and deubiquitination (DUB).

145 the 19S complex is responsible for substrate deubiquitination during proteasomal degradation.

146 Subsequently, following deubiquitination, enhanced RIM1alpha directly binds to C

147 Here, we identified the deubiquitination enzyme (DUB) USP20 as a pivotal regulat

148 c protein, in which the K63 linkage-specific deubiquitination enzyme AMSH [associated molecule with t

149 Ubp3 is a deubiquitination enzyme and a member of a large family o

150 mechanism by which Ci/Gli is stabilized by a deubiquitination enzyme and identify Usp7/HUASP as a cri

151 ilitate the deubiquitinating activity of the deubiquitination enzyme BRCC36 or the E3 ligase activity

152 report we show that EBNA3C can function as a deubiquitination enzyme capable of deubiquitinating itse

153 In addition, the deubiquitination enzyme Cylindromatosis (CYLD) negativel

154 A20 harbors a deubiquitination enzyme domain and can employ multiple m

155 ified BRCA1-associated protein-1 (BAP1) as a deubiquitination enzyme for gamma-tubulin.

156 Among these, Cezanne is a known deubiquitination enzyme that inhibits NF-kappaB activity

157 th increased expression of A20, an essential deubiquitination enzyme, and sustained A20-IRAK1 associa

158 ted by the discoveries of ubiquitination and deubiquitination enzymes as well as ubiquitin-binding pr

159 These include the deubiquitination enzymes CYLD and A20 that inhibit IKK,

160 Disassembly of the polyubiquitin chains by deubiquitination enzymes prevented TAK1 and IKK activati

161 subunit DNA repair complex, and eventually a deubiquitination event once the DNA repair reaction has

162 rated turnover of ubiquitin, indicating that deubiquitination events catalyzed by Ubp6 prevent transl

163 ted the importance of dynamic ubiquitination-deubiquitination events in regulating this canonical NF-

164 4 coordinate a cascade of ubiquitination and deubiquitination events that sort CXCR4 to the degradati

165 supporting the requirement of ubiquitination/deubiquitination for normal synaptic development and rep

166 consistent and robust underexpression of the deubiquitination gene ubiquitin carboxyl-terminal hydrol

167 that contain ubiquitin-binding domains, and deubiquitination govern the itineraries of cargo protein

168 Deubiquitination has emerged as an essential regulatory

169 ance and mechanism of degradation-associated deubiquitination has remained unclear.

170 Histone H2B ubiquitination and deubiquitination have been implicated in transcriptional

171 dies aiming to understand ubiquitination and deubiquitination have employed unanchored ubiquitin chai

172 feedforward loop of NLRC5 ubiquitination and deubiquitination, highlighting a new pathway modulating

173 Interestingly, UCH-L1 catalyzes its own deubiquitination in an intramolecular manner, thereby re

174 itinase and uncovers a critical role for H2B deubiquitination in cotranscriptional pre-mRNA processin

175 gesting a novel mechanism regulating histone deubiquitination in higher organisms.

176 is work, we describe the role of histone H2B deubiquitination in the activation of gene expression an

177 assays revealed that USP12 regulates histone deubiquitination in the mesoderm and at specific gene pr

178 1 fulfills a novel dual role in coordinating deubiquitination in the MVB pathway.

179 consequence of a perturbation of histone H2B deubiquitination in the timing of the floral transition

180 17 is monoubiquitinated and promotes its own deubiquitination in vivo.

181 es involved in histone H2B ubiquitination or deubiquitination, including RAD6, BRE1, LGE1, CDC73, UBP

182 Overall, we demonstrate a novel, deubiquitination-independent function for USP14 in influ

183 regulates synaptic function through a novel, deubiquitination-independent mechanism.

184 verexpression of an atx3 mutant defective in deubiquitination inhibits the degradation of misfolded E

185 Deubiquitination is a critical event required for Fancd2

186 Interestingly, p97-associated deubiquitination is also involved in degradation of a so

187 At the proteasome, deubiquitination is an essential preprocessing event tha

188 This ubiquitination-deubiquitination is conceptually reminiscent of the gluc

189 to ataxin-3, further explaining how ataxin-3 deubiquitination is coupled to parkin ubiquitination.

190 se for histone H2A and demonstrates that H2A deubiquitination is critically involved in cell cycle pr

191 n the first 205 residues of the protein, and deubiquitination is dependent on a cysteine at position

192 tion and is consistent with a model in which deubiquitination is necessary for the accumulation of H3

193 iptional regulation, but the function of H2B deubiquitination is not well defined, particularly in hi

194 Rapid deubiquitination is required for efficient degradation b

195 activation in T cells, the regulation of its deubiquitination is unclear.

196 The reversal of ubiquitination, or deubiquitination, is equally critical to neuronal functi

197 RNA knockdown of AMSH or UBPY also impaired deubiquitination, lysosomal trafficking, and degradation

198 n and characterization of ubiquitination and deubiquitination machinery that regulate NF-kappaB.

199 Our results suggest that histone H2A deubiquitination may account, at least in part, for the

200 uggest that NLRP3 is activated by a two-step deubiquitination mechanism initiated by Toll-like recept

201 tion of NLRP3 inflammasome is regulated by a deubiquitination mechanism.

202 eceptors, drives rapid, CYLD-mediated PSD-95 deubiquitination, mobilizing and depleting PSD-95 from s

203 s the formation of a quaternary complex, the deubiquitination module (DUBm) of SAGA, which is compose

204 The deubiquitination module (DUBm) of the SAGA complex is a

205 acetylase complex, the SWR1 complex, the H2B deubiquitination module of SAGA, the proteasome, Set1, a

206 Consistent with a functional role for deubiquitination, mutation of the cytoplasmic lysines of

207 We report that receptor deubiquitination occurs between early endosomes and lyso

208 ntagonizes Nedd4-1 function by promoting the deubiquitination of AMPARs.

209 ar mechanisms involved in ubiquitination and deubiquitination of AMPARs.

210 results suggest that both ubiquitination and deubiquitination of Atg19p are required for its full fun

211 The time course of ubiquitination and deubiquitination of beta-arrestin correlates with its as

212 was increased dramatically, suggesting that deubiquitination of beta-arrestin triggers its dissociat

213 USP33) binds beta-arrestin2 and leads to the deubiquitination of beta-arrestins.

214 catalytically inactive YopJ mutant, promoted deubiquitination of cellular proteins and cleaved both K

215 tin-specific proteases (USPs) that carry out deubiquitination of cellular substrates are poorly under

216 located in early endosomes and regulates the deubiquitination of CFTR and its trafficking in the post

217 novel function for USP10 in facilitating the deubiquitination of CFTR in early endosomes and thereby

218 Deubiquitination of FANCD2 is mediated by the ubiquitin

219 n this pathway is the monoubiquitination and deubiquitination of FANCD2.

220 Monoubiquitination and deubiquitination of FANCD2:FANCI heterodimer is central

221 Therefore, Wnt-induced deubiquitination of FoxM1 represents a novel and critica

222 ncovers a new mechanism for BAP1 involved in deubiquitination of gamma-tubulin, which is required to

223 st single gene disorder linked to defects in deubiquitination of H2AK119Ub1 and suggests an important

224 sphorylated H2AY57 (H2AY57p), which inhibits deubiquitination of H2B by the SAGA complex as well as r

225 Deubiquitination of H2B by the Spt-Ada-Gcn5 acetyltransf

226 red for interaction with HCF-1N and mediates deubiquitination of HCF-1N by BAP1.

227 m to the nucleus from the cytosol to control deubiquitination of histone H2B and spliceosomal protein

228 One role is deubiquitination of histone H2B, and this activity resid

229 We further show that deubiquitination of ILV cargoes is inhibited via Doa4 bi

230 work uncovers a novel role for USP8-mediated deubiquitination of K6-linked ubiquitin conjugates from

231 Rather, SGTA actively promotes the deubiquitination of mislocalized proteins that are alrea

232 ed suppression of cell proliferation but not deubiquitination of monoubiquitinated histone 2A lysine

233 Deubiquitination of monoubiquitinated proteins is effect

234 Thus, by mediating USP10-dependent deubiquitination of NEMO, MCPIP1 induction serves as a n

235 NF-kappaB activity and demonstrate that the deubiquitination of NF-kappaB by USP7 is critical for ta

236 USP7 deubiquitination of NF-kappaB leads to increased transcr

237 r show that signaling by ATP can also induce deubiquitination of NLRP3 by a mechanism that is not sen

238 both mouse and human cells, indicating that deubiquitination of NLRP3 is required for its activation

239 ale gametogenesis in plants and suggest that deubiquitination of one or more targets by UBP3/UBP4 is

240 ted I50 [malate and Asp] values) via in vivo deubiquitination of p110 to p107, and subsequent phospho

241 action, resulting in enhanced USP10-mediated deubiquitination of p53, and consequently increased p53

242 Moreover, ataxin-3-dependent deubiquitination of parkin required the catalytic cystei

243 ls and led to cell death, presumably through deubiquitination of PCNA and the inability to repair dam

244 Importantly, deubiquitination of PCNA could be detected endogenously

245 Thus, deubiquitination of PCNA, normally deubiquitinated by ce

246 activity is inhibited to prevent unwarranted deubiquitination of polyubiquitinated proteins.

247 RAD51 hinders RAD51-BRCA2 interaction, while deubiquitination of RAD51 facilitates RAD51-BRCA2 bindin

248 Ubiquitination and deubiquitination of receptor-interacting protein 1 (RIP1

249 , a ubiquitin-editing enzyme responsible for deubiquitination of RIP1 and subsequent termination of N

250 uggesting a positive role for USP15-mediated deubiquitination of RORgammat in Th17 differentiation.

251 d a complex with Smad7 that facilitated CYLD deubiquitination of Smad7 at lysine 360 and 374 residues

252 T cells and the development of Tregs through deubiquitination of Smad7.

253 TGF-beta-induced pro-oncogenic responses via deubiquitination of SMAD7.

254 Ubp8-mediated deubiquitination of Snf1 affects the stability and phosp

255 tylation, methylation and demethylation, and deubiquitination of specific amino acid residues in hist

256 nd showed a substantial defect in the linear deubiquitination of target molecules.

257 Our results suggest that deubiquitination of the activator is critical for transc

258 4 and USP14 is paralleled by USP14-catalyzed deubiquitination of the receptor; knockdown of endogenou

259 pathway dependent on the export in Xpo1p and deubiquitination of the RNAPI large subunit Rpa190p by U

260 rs to provide a time window allowing gradual deubiquitination of the substrate by Ubp6.

261 ATP-dependent, degradation-coupled deubiquitination of the substrate is required both for e

262 urvival and growth of prostate cancer cells, deubiquitination of these sites has an equally important

263 t with conformational plasticity, permitting deubiquitination of three of the most abundant polyubiqu

264 e Tip60 stability by promoting USP7-mediated deubiquitination of Tip60.

265 motif within DUBA was required for efficient deubiquitination of TRAF3 and optimal suppression of IFN

266 of TAX1BP1, A20 is impaired in RIP1 binding, deubiquitination of TRAF6 and inhibition of NF-kappaB ac

267 deubiquitinating enzyme and is required for deubiquitination of TRAF6, thus limiting RANKL-induced o

268 ances Usp15 binding to ubH2B and facilitates deubiquitination of ubH2B in free histones but not in nu

269 0 can directly impair IKK activation without deubiquitination or impairment of ubiquitination enzymes

270 that it is also likely to be targeted by the deubiquitination pathway.

271 nal modifications, including ubiquitination, deubiquitination, phosphorylation, and degradation contr

272 1) as a component of the Polycomb repressive deubiquitination (PR-DUB) complex.

273 Post-translational ubiquitination and deubiquitination processes involving the AMSH1 deubiquit

274 18 function and suggest that damage-specific deubiquitination promotes a switch from Rad18*Ub-Rad18 c

275 The deubiquitination-promoting effect of ASXM requires intra

276 nd is required for iNOS interaction with the deubiquitination protein UCH37.

277 emical activities, including ubiquitination, deubiquitination, protein complex segregation, and targe

278 We further followed the deubiquitination reaction of Ub-AMC and K48-linked IQF-d

279 change of histone H2A monoubiquitination and deubiquitination reflects the succession of transcriptio

280 Deubiquitination regulates formation of endocytic sites

281 A balance between ubiquitination and deubiquitination regulates numerous cellular processes a

282 Thus, deubiquitination regulates the supply of active thyroid

283 ecular mechanism underpinning its reversible deubiquitination remains poorly defined.

284 whether or not they can also mediate histone deubiquitination remains unknown.

285 F1 complex also deubiquitinates PCNA-Ub, and deubiquitination requires the PCNA-binding protein hELG1

286 Consequently, USP8-mediated deubiquitination slows progression of EGFR past the earl

287 model, wherein a cycle of H2B ubiquitination/deubiquitination specifies Ser2P to regulate elongation

288 The ubiquitination and deubiquitination status of PRP31 regulates its interacti

289 vidence that atx3 may promote p97-associated deubiquitination to facilitate the transfer of polypepti

290 e for ubiquitinated proteins and links their deubiquitination to their degradation.

291 hanistic implications for substrate binding, deubiquitination, unfolding, and degradation.

292 CRY1 and enhances its protein stability via deubiquitination upon serum shock.

293 Through deubiquitination, USP13 stabilizes and upregulates MITF

294 Through its effects on MITF deubiquitination, USP13 was observed to modulate express

295 P13) that appears to be responsible for MITF deubiquitination, utilizing a short hairpin RNA library

296 ociation and subsequent USP20-mediated TRAF6 deubiquitination were beta-arrestin2-dependent.

297 ficient DNA crosslink repair requires FANCD2 deubiquitination, whereas FANCD2 monoubiquitination is n

298 SP14 by RNA interference (RNAi) blocks CXCR4 deubiquitination, whereas overexpression of USP14 promot

299 Part of the pathway involves deubiquitination, which is carried out by cystein protea

300 monious use of molecular contacts to achieve deubiquitination, with less than 1,000 A(2) of accessibl