ライフサイエンスコーパス: deuterium

1 ents from plasmons in dynamically compressed deuterium.

2 nsulator-to-metal transition in dense liquid deuterium.

3 FEM) depots using an 8-week incorporation of deuterium ((2)H) from (2)H2O into the DNA of adipocytes

4 Raman scattering microscopy with integrated deuterium and alkyne labeling.

5 The production of pure deuterium and the removal of tritium from nuclear waste

6 ssfully applied to the high incorporation of deuterium and tritium in 18 drug molecules, which meet t

7 Deuterium- and tritium-labeled pharmaceutical compounds

8 ng peptide mimics of the S12 protein bearing deuterium at the 3 pro-R or 3 pro-S positions of the tar

9 PUFAs containing the heavy hydrogen isotope deuterium at the site of peroxidation (D-PUFA) prevented

10 deuterated syn-CD3CHOO is shown to result in deuterium atom transfer and release OD radical products.

11 on substrates having an increasing number of deuterium atoms at symmetry-related sites.

12 form shifts the mass of PCs by the number of deuterium atoms in the salt, while the mass of PSs remai

13 Selective incorporation of deuterium atoms into molecules is of high interest for l

14 ced activation (CIA), time-resolved hydrogen/deuterium back exchange (HDX) and trapped ion mobility s

15 First, we charged a ferritic steel with deuterium by means of electrolytic loading to achieve a

16 fforded by selective incorporation of carbon-deuterium (C-D) bonds, which provide frequency-resolved

17 ion with site-selective labeling with carbon-deuterium (C-D) vibrational probes, we characterized the

18 evelop site-specifically incorporated carbon-deuterium (C-D), cyano (CN), thiocyanate (SCN), and azid

19 Localizing the incorporated deuterium content on a single residue basis increases th

20 study, 264 peptides were analyzed for their deuterium content, providing almost complete sequence co

21 ude that comets containing water enriched in deuterium contributed significantly <20% of the water in

22 ocol can efficiently and selectively install deuterium (D) and tritium (T) at alpha-amino sp(3) carbo

23 ly with specific amounts of hydrogen (H) and deuterium (D).

24 (HD) (v = 1, j = 2) collides with molecular deuterium (D2) to form HD (v = 1, j = 1), where v and j

25 50 gigapascals; we do not observe phase V in deuterium (D2).

26 llular turnover and longevity by quantifying deuterium dilution kinetics in YFV-specific CD8 T cells

27 A deuterium dilution technique or bioelectrical impedance

28 Fat-free mass (FFM) was assessed by deuterium dilution technique.

29 ly used for safe quantitative measurement of deuterium enrichment into DNA of proliferating cells.

30 We observe a deuterium equidistant between the Schiff base and the C-

31 The measurement of a deuterium equilibrium isotope effect (EIE) for the aryl

32 decades are inferred from annually averaged deuterium excess (d-excess) measurements from six sites.

33 e experiments, the use of gas-phase hydrogen/deuterium exchange (HDX) combined with IMS-MS/MS techniq

34 form utilizing two methods based on hydrogen-deuterium exchange (HDX) coupled with mass spectrometry

35 Hydrogen-deuterium exchange (HDX) coupled with mass spectrometry

36 sible database of carefully curated hydrogen/deuterium exchange (HDX) data extracted from the literat

37 is based on early folding data from hydrogen deuterium exchange (HDX) data from NMR pulsed labelling

38 NMR hydrogen-deuterium exchange (HDX) experiments indicate the presen

39 vent-accessible surface area and by hydrogen-deuterium exchange (HDX) experiments.

40 The rate of hydrogen-deuterium exchange (HDX) in aqueous droplets of phenethy

41 In the present study, hydrogen-deuterium exchange (HDX) in conjunction with mass spectr

42 At the same time, hydrogen-deuterium exchange (HDX) is a well-known technique for s

43 Hydrogen/deuterium exchange (HDX) mass spectrometry (MS) reports

44 Here, we demonstrate the utility of hydrogen-deuterium exchange (HDX) mass spectrometry (MS) to measu

45 ainst soluble ester substrates, and hydrogen-deuterium exchange (HDX) mass spectrometry revealed that

46 Here we have used hydrogen/deuterium exchange (HDX) mass spectrometry to determine

47 Here the authors employ hydrogen/deuterium exchange (HDX) mass spectrometry to study the

48 Hydrogen-deuterium exchange (HDX) shows that AFF4 helix 2 is stab

49 arbohydrate structures by gas-phase hydrogen/deuterium exchange (HDX) to discover that the exchange r

50 use of a combined method including hydrogen-deuterium exchange (HDX), fast photochemical oxidation o

51 CD81bs by electron microscopy (EM), hydrogen-deuterium exchange (HDX), molecular dynamics (MD), and c

52 ed mass spectrometry-detected amide hydrogen/deuterium exchange (HDXMS) experiments on IkappaBalpha a

53 Differential hydrogen/deuterium exchange analysis demonstrates that SPA70 and

54 Moreover, hydrogen-deuterium exchange analysis of the point-mutated variant

55 Former studies relying on hydrogen/deuterium exchange analysis suggest that DnaC bound to D

56 Hydrogen/deuterium exchange and chemical cross-linking coupled to

57 Hydrogen/deuterium exchange and chemical crosslinking showed that

58 Using hydrogen/deuterium exchange and cross-linking-mass spectrometry w

59 , for full-length human c-Src using hydrogen-deuterium exchange and mass spectrometry.

60 at make up the folding core include hydrogen-deuterium exchange and Phi-value analysis and can be exp

61 X-ray fibre diffraction, hydrogen-deuterium exchange and solid-state NMR studies map the b

62 Carbaporphyrins and carbachlorins underwent deuterium exchange at the meso-positions with deuteriate

63 The C-terminal tails demonstrate more rapid deuterium exchange behavior when compared with the kinas

64 A comparison of differential deuterium exchange between active (GMPPNP-bound) and ina

65 We found differences in hydrogen-deuterium exchange between peptide-loaded and peptide-re

66 Hydrogen/deuterium exchange combined with mass spectrometry furth

67 We employed hydrogen/deuterium exchange combined with mass spectrometry to id

68 Here, using hydrogen-deuterium exchange coupled to mass spectrometry (HDX-MS)

69 We used hydrogen-deuterium exchange coupled to mass spectrometry and nega

70 Here, we use hydrogen-deuterium exchange coupled to mass spectrometry to analy

71 nally demonstrates the potential of hydrogen-deuterium exchange coupled to mass spectrometry to explo

72 Using hydrogen-deuterium exchange coupled to mass spectrometry, combine

73 mapped intermolecular contacts with hydrogen-deuterium exchange coupled to mass spectrometry.

74 n CYP46A1 by using a combination of hydrogen-deuterium exchange coupled to MS, computational modeling

75 apoE3 and E4 functionality, we used hydrogen-deuterium exchange coupled with a fragment separation me

76 layer nanodiscs, subjecting them to hydrogen-deuterium exchange coupled with mass spectrometry (HDX-M

77 Hydrogen/deuterium exchange coupled with mass spectrometry (HDX-M

78 rion protein, PrP(C), together with hydrogen-deuterium exchange coupled with mass spectrometry (HXMS)

79 Hydrogen-deuterium exchange coupled with mass spectrometry reveal

80 Furthermore, hydrogen-deuterium exchange coupled with mass spectrometry showed

81 Using hydrogen/deuterium exchange coupled with mass spectrometry to cha

82 Here, we employed hydrogen/deuterium exchange coupled with mass spectrometry to exp

83 on of their epitope diversity using hydrogen deuterium exchange coupled with mass spectrometry.

84 Here, using hydrogen-deuterium exchange coupled with MS (HDX-MS), we probed t

85 re and after substrate binding, the hydrogen/deuterium exchange data in the L2' and 130's regions sug

86 Here, we report amide hydrogen/deuterium exchange data that reveal long-range allosteri

87 Notably, both hydrogen/deuterium exchange experiments and in vitro binding assa

88 However, hydrogen/deuterium exchange experiments confirm the second harmon

89 g residues based on pulsed labeling hydrogen deuterium exchange experiments.

90 sis caused significant increases in hydrogen-deuterium exchange in sub-regions of the peptide-binding

91 tantially higher protection against hydrogen/deuterium exchange in the C-terminal region near the N-g

92 Furthermore, by comparing the hydrogen/deuterium exchange in the mature part of NGF and proNGF,

93 e used mass spectrometry to monitor hydrogen/deuterium exchange in various regions of FLASH, Lsm11 an

94 steps, we analyzed the patterns of hydrogen-deuterium exchange in vimentin and in four variants carr

95 Hydrogen-deuterium exchange indicates protection of a surface on

96 tional dynamics of the enzyme using hydrogen/deuterium exchange kinetics.

97 Hydrogen/deuterium exchange mass spectrometry (HDX MS) was used i

98 mical modifications within the CDR, hydrogen-deuterium exchange mass spectrometry (HDX MS) was used t

99 traditional analytical methods with hydrogen/deuterium exchange mass spectrometry (HDX MS), native ma

100 Hydrogen/deuterium exchange mass spectrometry (HDX-MS) and molecu

101 r structure information provided by hydrogen/deuterium exchange mass spectrometry (HDX-MS) in the pro

102 Finally, hydrogen-deuterium exchange mass spectrometry (HDX-MS) indicates

103 integrity of therapeutic proteins, hydrogen-deuterium exchange mass spectrometry (HDX-MS) is increas

104 Hydrogen/deuterium exchange mass spectrometry (HDX-MS) is now a r

105 e use comprehensive mutagenesis and hydrogen deuterium exchange mass spectrometry (HDX-MS) to identif

106 ALP) technology can be coupled with hydrogen-deuterium exchange mass spectrometry (HDX-MS) to investi

107 ing the complementary approaches of hydrogen/deuterium exchange mass spectrometry (HDX-MS), fast phot

108 ic activity that is very useful for hydrogen/deuterium exchange mass spectrometry (HX-MS).

109 resonance, analytical rheology, and hydrogen-deuterium exchange mass spectrometry (HXMS), we decipher

110 tegrated approach of cross-linking, hydrogen-deuterium exchange mass spectrometry (MS), electron micr

111 ues 775-818) using a combination of hydrogen-deuterium exchange mass spectrometry and isothermal titr

112 omeric structure of the protein, on hydrogen-deuterium exchange mass spectrometry data, and on the ro

113 Hydrogen-deuterium exchange mass spectrometry demonstrated that t

114 Hydrogen/deuterium exchange mass spectrometry demonstrated that t

115 Here, hydrogen/deuterium exchange mass spectrometry indicated that casp

116 Guided by hydrogen/deuterium exchange mass spectrometry results, we have em

117 of the muPA:nanobody complexes and hydrogen-deuterium exchange mass spectrometry revealed molecular

118 Finally, hydrogen-deuterium exchange mass spectrometry reveals that the in

119 NMR and amide hydrogen-deuterium exchange mass spectrometry showed that the Ika

120 In our hydrogen-deuterium exchange mass spectrometry study, 264 peptides

121 zyme-linked immunosorbent assay and hydrogen-deuterium exchange mass spectrometry that 7 of 9 anti-hu

122 e show by mutagenesis, pulldown and hydrogen/deuterium exchange mass spectrometry that this peptide i

123 We used the method of hydrogen/deuterium exchange mass spectrometry to address the impo

124 Here, we employed hydrogen-deuterium exchange mass spectrometry to describe the str

125 Here, we use hydrogen/deuterium exchange mass spectrometry to probe the inner

126 In this study, we used amide hydrogen/deuterium exchange mass spectrometry, a sensitive biophy

127 aphy, small-angle X-ray scattering, hydrogen-deuterium exchange mass spectrometry, and mutational map

128 using neutralization escape mutant analysis, deuterium exchange mass spectrometry, and x-ray crystall

129 ed diubiquitin, in combination with hydrogen-deuterium exchange mass spectrometry, enable us to recon

130 Hydrogen-deuterium exchange mass spectrometry, limited proteolysi

131 examined through crystallographic, hydrogen-deuterium exchange mass spectrometry, mutagenesis and fu

132 Using hydrogen/deuterium exchange mass spectrometry, we measured the co

133 fferential scanning fluorimetry and hydrogen-deuterium exchange mass spectrometry, we show here that

134 sterase8 (PDE8), monitored by amide hydrogen-deuterium exchange mass spectrometry, we show progressiv

135 Using NMR and hydrogen-deuterium exchange mass spectrometry, we showed that 3G1

136 matography, circular dichroism, and hydrogen-deuterium exchange mass spectrometry.

137 s is evident in the N197Q mutant by hydrogen-deuterium exchange mass spectrometry.

138 rcular dichroism, fluorescence, and hydrogen-deuterium exchange mass spectrometry.

139 ation native mass spectrometry, and hydrogen-deuterium exchange mass spectrometry.

140 mbination of biochemical assays and hydrogen-deuterium exchange mass spectrometry.

141 rapidly with water as indicated by hydrogen-deuterium exchange measurements.

142 Using hydrogen/deuterium exchange monitored by Fourier transform ion cy

143 Here, equilibrium unfolding and hydrogen/deuterium exchange monitored by mass spectrometry indica

144 Hydrogen/deuterium exchange monitored by mass spectrometry is a s

145 In this work, hydrogen/deuterium exchange MS (H/DX-MS) was used to map the loca

146 mutagenesis, resonance Raman (RR), hydrogen-deuterium exchange MS (HDX-MS) methods, and molecular dy

147 Herein, we employed hydrogen-deuterium exchange MS (HDXMS) to spatially resolve chang

148 Hydrogen-deuterium exchange MS revealed that membrane-resident HR

149 se assays and through analysis with hydrogen-deuterium exchange MS.

150 Using hydrogen-deuterium exchange NMR and fluorescence quenching techni

151 e analysis that makes use of a nonreversible deuterium exchange of C-H protons on the carbohydrate ba

152 ed analytical method to measure the hydrogen/deuterium exchange of proteins in solution, we analyzed

153 Hydrogen-deuterium exchange studies coupled with mass spectrometr

154 zation mass spectrometry coupled to hydrogen-deuterium exchange studies followed by mutagenic analysi

155 Mapping deuterium exchange to peptides within the enzyme highlig

156 Hydrogen-deuterium exchange was used to map the Rag binding site

157 ic species undergo room-temperature hydrogen-deuterium exchange with an alkane hydrocarbon reagent, i

158 chimeras, photo-affinity labeling, hydrogen-deuterium exchange, and crystallography of the ligand-bi

159 ed by small angle x-ray scattering, hydrogen/deuterium exchange, and mass spectrometry.

160 ed allotype-specific differences in hydrogen-deuterium exchange, consistent with the notion that MHC

161 Hydrogen-deuterium exchange, disulfide crosslinking and molecular

162 iving red blood cells (RBCs), using hydrogen/deuterium exchange-based mass spectrometry (H/DX-MS).

163 Next, hydrogen-deuterium exchange-mass spectrometry (HDX-MS) was employ

164 Using Hydrogen-Deuterium Exchange-Mass Spectrometry (HDX-MS) we show th

165 sis, site-directed mutagenesis, and hydrogen/deuterium exchange-mass spectrometry.

166 compared with agonists by employing hydrogen/deuterium exchange.

167 ed on biophysical measurements with hydrogen-deuterium exchange/mass spectrometry, surface plasmon re

168 molecular dynamics simulation, and hydrogen-deuterium-exchange analysis, we demonstrate that transme

169 Here, we show how hydrogen/deuterium-exchange mass spectrometry (HDX-MS) provides d

170 Here, we adapted hydrogen/deuterium-exchange mass spectrometry (HDX-MS) to analyze

171 Hydrogen-deuterium-exchange mass spectrometry demonstrates that t

172 By hydrogen/deuterium-exchange mass spectrometry, these HIC-pure tri

173 In combination with hydrogen/deuterium-exchange, solution scattering data and DNA-bin

174 ent energy flow to vibrational motion of the deuterium fluoride (DF) product that competes with dissi

175 Substitution of deuterium for hydrogen has been shown to lead to massive

176 The isotope effect (change of TC upon Deuterium for Hydrogen substitution) originates from hig

177 Here we employed equilibrium hydrogen/deuterium fractionation factors to measure backbone hydr

178 ed in first-order, time-dependent washout of deuterium from 6a.

179 Herein, we applied hydrogen-deuterium (H/D) exchange MS (HDX-MS) of full-length Esch

180 The pH dependence, hydrogen/deuterium (H/D) isotope effect, and temperature dependen

181 s via radical pathway using D2O as source of deuterium has been developed.

182 ative-state dynamics, as studied by hydrogen-deuterium (HD) exchange experiments analyzed by NMR spec

183 d the rotationally inelastic process wherein deuterium hydride (HD) (v = 1, j = 2) collides with mole

184 Pulse EPR data reveal an exchangeable deuterium hyperfine coupling of strength |T| = 0.7 MHz,

185 s by monitoring the exchange of hydrogen for deuterium in solution.

186 e intermediate required both the presence of deuterium in the substrate and, importantly, the use of

187 High deuterium incorporation (up to 49%) in acidic C-H bonds

188 Importantly, complete deuterium incorporation from stoichiometric D2O has also

189 High deuterium incorporation occurs at the alpha-carbon (70-9

190 gas, drift time in He and D2O buffer gases, deuterium incorporation pattern (isotopic distribution),

191 corporation pattern (isotopic distribution), deuterium incorporation pattern after collisional activa

192 ter collisional activation, and fragment ion deuterium incorporation pattern upon collision-induced d

193 Preliminary deuterium incorporation studies have been performed to u

194 While deuterium incorporation was similar across most of the p

195 ucts in good yields and with a high level of deuterium incorporation.

196 bstituting the transferred hydrogen atoms by deuterium, indicating that the process is governed by tu

197 drogen atom, as evidenced by the transfer of deuterium into 5'-deoxyadenosine (5'-dAH).

198 Results on kinetic deuterium isotope effect and quenching studies are in co

199 cal shifts, a Steiner-Limbach correlation, a deuterium isotope effect as well as quantitative values

200 , high noncompetitive intermolecular kinetic deuterium isotope effects (>/= 5.5) were observed for al

201 Deuterium isotope effects, typical of a concerted metala

202 the hydrogen bond geometry upon hydrogen-to-deuterium isotope exchange is obtained from a comparison

203 e-cell Raman microspectroscopy, coupled with deuterium isotope probing (Raman-DIP), provides a cultur

204 carbonyl (13)C KIE and a large primary alpha-deuterium KIE support rate-determining enamine formation

205 bined with simulation reveal a large primary deuterium kinetic isotope effect of 3.3 on the covalent

206 Primary deuterium kinetic isotope effects (1 degrees DKIE) on (k

207 measurement of [Formula: see text]-secondary deuterium kinetic isotope effects (KIEs) at all sites of

208 show apparent bimolecular rate constants and deuterium kinetic isotope effects that increase in propo

209 The experimentally observed rate law, deuterium kinetic isotope effects, and identification of

210 acid-independent and displays no observable deuterium kinetic isotopic effect.

211 The PET tracer (11)C-deuterium-L-deprenyl ((11)C-DED) has been used to visual

212 ncorrect conclusions since they scramble the deuterium label).

213 port the novel enantioselective synthesis of deuterium-labeled (R)- and (S)-rimantadine and the chara

214 one) in one method using their corresponding deuterium-labeled analogues as internal standards.

215 Furthermore, a synthetic access to deuterium-labeled analogues of these natural products ha

216 covered rearrangement was studied both using deuterium-labeled bicyclo[4.2.2]deca-2,4,7,9-tetraenes a

217 Deuterium-labeled cholesterol was used as the internal s

218 osphoric acid-catalyzed spiroketalization of deuterium-labeled cyclic enol ethers revealed a highly d

219 subjects using both heavy water (n = 4) and deuterium-labeled glucose (n = 9), a compound with more

220 Syntheses of analytical standards, including deuterium-labeled internal standards, are also described

221 opic methods, together with the specifically deuterium-labeled substrates, A[d2-C]V and AC[d8-V], to

222 ive multiprong studies involving the fate of deuterium-labeled substrates, EPR, trapping experiments,

223 studies, four artificial products containing deuterium-labeled SVOCs (eight phthalates and adipates)

224 while the X-ray structures of unlabeled and deuterium-labeled TTR are essentially identical, subunit

225 on in selected reaction monitoring mode with deuterium-labeled vitamin K1 as an internal standard.

226 Deuterium labeling and kinetic isotope effect experiment

227 The mechanistic pathway was supported by deuterium labeling experiment and X-ray crystallographic

228 Deuterium labeling experiments suggest a syn-migratory i

229 Deuterium labeling experiments support rapid and reversi

230 Kinetic study with extensive deuterium labeling experiments were performed to support

231 Energy-resolved mass spectrometry, deuterium labeling experiments, and theoretical calculat

232 ormations of 3a and 4 were investigated with deuterium labeling experiments, KIE and other kinetic st

233 direct catalytic method for formyl-selective deuterium labeling of aromatic aldehydes under mild cond

234 probe accurately retains its solution-phase deuterium labeling pattern.

235 nism of epoxide hydrogenolysis, and further, deuterium labeling studies revealed more mechanistic det

236 The deuterium labeling studies supports electrophilic pallad

237 Several controlled reactions along with deuterium labeling studies were carried out to establish

238 The collective data, including deuterium labeling studies, are consistent with a cataly

239 bidentate phosphines have been explored and deuterium labeling studies, the method of continuous var

240 was supported by the control experiments and deuterium labeling studies.

241 including with electron-deficient arenes and deuterium labeling studies.

242 ies of water associated with cellulose using deuterium labeling, neutron scattering and molecular dyn

243 Here, using human in vivo deuterium labeling, we demonstrate that classical monocy

244 Deuterium-labeling and stoichiometric experiments suppor

245 NMR spectra employing a deuterium-labeling approach enabled resolution of the di

246 Kinetic studies and deuterium-labeling experiments, as well as density funct

247 The kinetics data, coupled with deuterium-labeling experiments, support a mechanism invo

248 ell supported by the control experiments and deuterium-labeling studies and by isolating the azadiene

249 Lastly, deuterium-labeling studies indicate that deuterium scram

250 Deuterium-labeling studies suggest distinct mechanisms f

251 Deuterium-labeling studies support the involvement of a

252 Deuterium labelled analogues of the target analytes were

253 Here we show using a chemically-synthesized deuterium-labelled mechanistic probe, and heterologous g

254 to selectively monitor the incorporation of deuterium-labelled Phe into proteins in individual live

255 We used in vivo deuterium labelling to mark CD8 T cells that proliferate

256 Deuterium-labelling experiments were performed to identi

257 A deuterium lamp with bandpass filters and UV light-emitti

258 hotodissociation (UVPD) at 213 nm to measure deuterium levels at single residue resolution in HDX-MS

259 For the new strain, histidine hydrogen-deuterium mass spectrometry revealed altered packing arr

260 Muonic deuterium mud is the exotic atom formed by a deuteron an

261 e combined effect of SP-C and cholesterol by deuterium NMR and phosphorus NMR and by electron spin re

262 Deuterium NMR spectra indicate that bound cholesterol is

263 hich labile protons must not be exchanged by deuterium nuclei.

264 apes of the isotopically decoupled IR oxygen-deuterium (O-D) stretching mode of HDO water near small

265 On the one hand, the large enrichments in deuterium of the insoluble organic matter (IOM) isolated

266 me it induces a considerable decrease of the deuterium order parameter of POPC/(2)H31-POPS 3:1.

267 at overcome these limitations, in particular deuterium oxide (D2 O or heavy water).

268 Deuterium oxide (D2O) has been identified not only as a

269 sum synthesis over an extended period, using deuterium oxide have been shown to accurately reflect mu

270 enrichment and the rate of incorporation of deuterium oxide into newly synthesized muscle proteins w

271 ent kinetic isotope effect experiments using deuterium oxide reveal that the reactivation mechanism f

272 Deuterium oxide was used as nonretarded tracer.

273 body water by using stable isotope dilution (deuterium oxide) combined with body-weight changes.

274 The use of water, deuterium oxide, and H2O/D2O mixtures helped to distingu

275 ted on silica with liquid-phase hydrogen and deuterium peroxides at multiple pH values.

276 ethod performed in 1.25 min provided similar deuterium retention as an 8.5 min LC method conducted at

277 Deuterium scrambling and kinetic studies offer valuable

278 ly, deuterium-labeling studies indicate that deuterium scrambling does not take place in this sp(2) -

279 predicted to be reversible, consistent with deuterium-scrambling experiments.

280 (2)H line shapes for 140 resolved aliphatic deuterium sites.

281 on required for recruiting the HCC exchanges deuterium slowly and likely folds into a stable structur

282 reactivity and thiol pKa, and the absence of deuterium solvent kinetic isotope effects suggested step

283 xide (D2O) has been identified not only as a deuterium source but also as a crucial component in the

284 sults reveal that the choice of the hydrogen/deuterium source, the nature of the graphite (used as st

285 smaller than the r(d) value from electronic deuterium spectroscopy.

286 uctive phenotyping approach, so called Raman Deuterium Stable Isotope Probing (Raman-DIP), was develo

287 of this study was to radiolabel a novel bis-deuterium substituted l-deprenyl analog (fluorodeprenyl-

288 on to 1-methoxy-1-vinylcyclopropane, whereas deuterium-substituted 1-methoxycyclopropyl-d3-methylcarb

289 For redox reactions, deuterium tracing can provide additional information.

290 and NADPH enables accurate interpretation of deuterium tracing studies of redox cofactor and fatty ac

291 rticle imager (DPI) was used with a portable deuterium-tritium (DT) neutron generator to detect neutr

292 is reaction is a quark-level analogue of the deuterium-tritium nuclear fusion reaction (DT --> (4)He

293 For the analyzed heavy chain marker peptides deuterium uptake differences due to oxidation at the con

294 he CH2 domain of DTT-IYG showed differential deuterium uptake in the peptide region of the FG loop as

295 The local subunit-specific deuterium uptake of this polymerization-competent dimer

296 peptides in iC3b showed significantly higher deuterium uptake when compared with C3b, revealing more

297 uces protection of the Nef alphaB-helix from deuterium uptake, consistent with a role for alphaB in d

298 or due to the smaller quantum spacing of the deuterium vibrational levels.

299 tetrabenazine is a novel molecule containing deuterium, which attenuates CYP2D6 metabolism and increa

300 acement of the transferring hydrogen atom by deuterium, while replacing the transferring hydrogen ato