ライフサイエンスコーパス: deuterostome

1 locentrotus purpuratus, a basal invertebrate deuterostome.

2 f regeneration-specific gene expression in a deuterostome.

3 ic protostome or from a more closely related deuterostome.

4 in the sea urchin embryo, an early branching deuterostome.

5 conceived for sea urchins, nor for any other deuterostome.

6 tratigraphically are amongst the earliest of deuterostomes.

7 asal mode of germ line determination amongst deuterostomes.

8 urchin cytoskeletal genes to those of other deuterostomes.

9 ess sensing and response mechanisms in early deuterostomes.

10 great insights into the basal properties of deuterostomes.

11 of a Wnt-A ortholog thought to be absent in deuterostomes.

12 rged during the evolution of protostomes and deuterostomes.

13 he adults acquire a body plan unique for the deuterostomes.

14 ates and between invertebrate and vertebrate deuterostomes.

15 elomorpha as an early branching taxon in the deuterostomes.

16 suggest its phylogenetic position within the deuterostomes.

17 e to those found in spiralians, nematodes or deuterostomes.

18 he apparent absence of TCAM1 in invertebrate deuterostomes.

19 on even before divergence of protostomes and deuterostomes.

20 derm differentiation in both protostomes and deuterostomes.

21 ess of maximal indirect development in basal deuterostomes.

22 e sister group to the echinoderms within the deuterostomes.

23 study enteric nervous system regeneration in deuterostomes.

24 utionary history of Brachyury utilization in deuterostomes.

25 el system for studying these interactions in deuterostomes.

26 re of appendage formation in protostomes and deuterostomes.

27 ch have variously been regarded as proto- or deuterostomes.

28 e early anterior neuroectoderm (ANE) in many deuterostomes.

29 They were then considered deuterostomes.

30 Together, these three phyla comprise the deuterostomes.

31 s with diverging orientations in all studied deuterostomes.

32 GlyT1- and GlyT2-like genes in invertebrate deuterostomes.

33 stoma floridae, elucidating pNP evolution in deuterostomes.

34 tructure and function across protostomes and deuterostomes.

35 and mesoderm fates is not well understood in deuterostomes.

36 he development of multiple structures across deuterostomes.

37 t prior to the divergence of protostomes and deuterostomes.

38 s, 10 non-mammal vertebrates, 3 invertebrate deuterostomes, 13 insects, 6 worms and a yeast.

39 s, 13 non-mammal vertebrates, 3 invertebrate deuterostomes, 13 insects, 6 worms, yeast and sea hare.

40 ared after the divergence of protostomes and deuterostomes 450-600 million years ago, while NCBD was

41 clade that appears related to the protostome/deuterostome A clade of fibrillar collagens.

42 ips suggest that amphioxus shares with other deuterostomes a common mechanism for patterning along th

43 data indicate that in an ancestor of extant deuterostomes a remarkable and unique event in the evolu

44 Among extant deuterostomes, a skeleton in which each plate has the cr

45 indings, together with the identification of deuterostome achatin and luqin and protostome opioid pNP

46 last common ancestor of the protostomes and deuterostomes, an animal from which >98% of all describe

47 ventional view of the last common protostome-deuterostome ancestor (PDA) as a complex organism that p

48 ated myocytes were present in the protostome-deuterostome ancestor and that smooth myocytes later co-

49 c evidence for a well-ordered complex in the deuterostome ancestor for the hox1-hox9/10 region, with

50 We propose that the deuterostome ancestor may have had a diffuse nervous sys

51 of the early neurogenic domain in the common deuterostome ancestor of echinoderms and vertebrates.

52 lly in patterning pharyngeal structures in a deuterostome ancestor of vertebrates.

53 Here, we show that the deuterostome ancestor possessed a molecular toolkit homo

54 were probably inherited from the last common deuterostome ancestor, and then explore evolutionary tra

55 zed, or a noncentralized nervous system of a deuterostome ancestor.

56 go, while NCBD was present in the protostome/deuterostome ancestor.

57 ikingly different phyla from the last common deuterostome ancestor.

58 d part of the mucociliary sole in protostome-deuterostome ancestors and diversified independently int

59 fic mesenchymal-to-epithelial transitions in deuterostome ancestors.

60 urchin identifies conserved features of the deuterostome ancestral pathway, including positive feedb

61 s were probably overlapping in the ancestral deuterostome and came to abut at the MHB early in the ch

62 en used to gain insights into the origins of deuterostome and chordate body plans.

63 Whereas the genomes of plants and deuterostome and chordate invertebrates harbor large ars

64 Single homologs are present in basal deuterostome and insect genomes, including Drosophila, a

65 ), is found in sponges, cnidarians, and both deuterostome and protostome groups but does not appear t

66 the sea urchin's role as a model system for deuterostome and, by extension, chordate development.

67 examines larval and adult body plans in the deuterostomes and discusses two distinct ways of evolvin

68 previously been proposed for protostomes vs deuterostomes and instead suggest that various features

69 fic gene novelties, including genes found in deuterostomes and marine microbes, but not other animals

70 r retinoic acid (RA) probably evolved in the deuterostomes and may be chordate-specific.

71 Thus, the divergence of deuterostomes and protostomes may have been accompanied

72 Deuterostomes and protostomes split about 670 million ye

73 egrins originated prior to the divergence of deuterostomes and protostomes.

74 he CK lineage, well before the divergence of deuterostomes and protostomes.

75 vertebrate genes prior to the divergence of deuterostomes and protostomes.

76 vertebrate genes prior to the divergence of deuterostomes and protostomes: in one case there was sig

77 e Mab-5 genes of nematodes and Hox6 genes of deuterostomes and would therefore have been present in t

78 e two pathways appears to be conserved among deuterostomes, and in the case of Notch at least, displa

79 e foremost morphological innovation of early deuterostomes, and is probably central to their filter-f

80 gin before the divergence of protostomes and deuterostomes, and may ancestrally have been involved in

81 nt capacity in the common ancestor of living deuterostomes, and that their specific role in the adapt

82 kowalevskii represent the derived state for deuterostomes, and we argue that functional evolution ac

83 e embryos reveal striking similarities among deuterostome ANE regulatory networks and the molecular m

84 Deuterostome animals exhibit widely divergent body plans

85 yzed the NAD kinases (NADKs) of a variety of deuterostome animals, finding two conserved internal dom

86 F cycling and Ca(2+) signaling in oocytes of deuterostome animals.

87 ionships between invertebrate and vertebrate deuterostomes are clearly important for understanding ou

88 lts support the strength of this nonchordate deuterostome as a pivotal developmental and evolutionary

89 within the Class II, Spfkh1 groups with the deuterostomes as opposed to the protostomes.

90 ring relationship that also later serves, in deuterostomes, as the anatomical site of the anus.

91 body-axis formation and organization across deuterostomes, at stages before morphological difference

92 lex, ancient genetic regulatory scaffold for deuterostome body patterning that degenerated in amphiox

93 In vertebrates (deuterostomes), brain patterning depends on signals from

94 sentative species of both the protostome and deuterostome branches of the metazoan phylogenetic tree.

95 and 530 Ma evidently includes the protostome-deuterostome branching, diversification of independent h

96 elopment and gastrulation are similar in all deuterostomes, but, in chordates, the anterior-posterior

97 Here we show that protostome and deuterostome cartilage share structural and chemical pro

98 raction, structure, and functionality of all deuterostome cells and have major functions in cellular

99 support of pharyngeal gill slits as a shared deuterostome character, provide the foundation for the e

100 ither at the base of the bilateria or of the deuterostome clade, we report the ligand binding propert

101 and echinoderms, which together make up the deuterostome clade.

102 ata acoelomorphs might instead be degenerate deuterostomes closely related to Xenoturbella, muddying

103 ea urchin representatives thus expanding the deuterostome complement.

104 Deuterostomes comprise vertebrates, the related inverteb

105 stent with the "ecdysozoa" hypothesis) or to deuterostomes (consistent with "coelomata").

106 e beginning to yield important insights into deuterostome developmental mechanisms.

107 This larva, typically for the ancestral deuterostome dipleurula larval type that it represents,

108 family originated before the protostomes and deuterostomes diverged, over 525 million years ago.

109 vertebrate divergence, after the protostome-deuterostome divergence but before the amniote-amphibian

110 ted to chordates and postdate the protostome/deuterostome divergence, they must have evolved from bil

111 g., mollusks, annelids, and arthropods) and "deuterostomes" (e.g., echinoderms and chordates) display

112 oans, bilaterians, chordate and non-chordate deuterostomes, ecdysozoan and lophotrochozoan protostome

113 tified in all three groups of the Bilateria (deuterostomes, ecdysozoans, and lophotrochozoans).

114 opods, annelids, and mollusks) diverged from deuterostomes (echinoderms and chordates) about 670 mill

115 appears to be lacking in more early-diverged deuterostomes (echinoderms, hemichordates), it is uncert

116 ranscription factors with conserved roles in deuterostome ectodermal anteroposterior (AP) patterning

117 mes suggest that patterning of the ancestral deuterostome embryo along its anterior-posterior axis du

118 ening between the gut and the outside of the deuterostome embryo breaks through at the extreme anteri

119 is present after fertilization whereas most deuterostome embryos show minimal polarity during the ea

120 a critical event in the early development of deuterostome embryos.

121 uggesting a common origin for protostome and deuterostome epidermal sensory cells in the ancestral bi

122 divergence of this novel gene family during deuterostome evolution and provide further evidence that

123 ly these findings suggest that a key step in deuterostome evolution was the development of lateral op

124 ave been maintained throughout the course of deuterostome evolution.

125 nciples underlie TAD compartmentalization in deuterostome evolution.

126 of the notochord represented a milestone in Deuterostome evolution.

127 ships between them might have changed during deuterostome evolution.

128 amphioxus and vertebrates or even earlier in deuterostome evolution.

129 rees, GlyT2-like sequences from invertebrate deuterostomes form a monophyletic subclade with vertebra

130 Data from diverse deuterostomes (frog, fish, mouse, and amphioxus) and fro

131 Analysis of the basic deuterostome genetic complement supports the sea urchin'

132 ne expansion in the urchin relative to other deuterostome genomes, whereas the stress sensor gene fam

133 A deuterostome Grl from the sea urchin Strongylocentrotus

134 rst evidence for a nodal orthologue in a non-deuterostome group.

135 To study the relationships among all deuterostome groups, we have assembled an alignment of m

136 Our findings suggest that the ancestral deuterostome had a population of biomineral-forming mese

137 that the common ancestor of protostomes and deuterostomes had a minimum complement of 14 Fox genes.

138 the last common ancestor of protostomes and deuterostomes had a prototype of the brains present in m

139 Several invertebrate deuterostomes have two paralogous glycine carrier genes,

140 bination, also including an SPS, upstream of deuterostome Hes repressor genes, which are also Notch t

141 ost of the components of both protostome and deuterostome Hh signaling pathways are present in anthoz

142 In the sea urchin, a basal deuterostome, Hh signaling is shown to participate in or

143 rgence of globin families in protostomes and deuterostomes (i.e. convergent evolution).

144 it from the common ancestor of copepods and deuterostomes, i.e. the ancestral bilaterians.

145 types of genes expected to be used in lower deuterostome immune functions.

146 ily are known to function in protostomes and deuterostomes in the specification of mesodermal fates.

147 Deuterostomes include the group we belong to (vertebrate

148 s of nodal have also been described in other deuterostomes, including ascidians and sea urchins, but

149 of the biology and evolution of nonchordate deuterostomes, invertebrate chordates, and vertebrates.

150 of adhesion proteins between protostome and deuterostome invertebrates and between invertebrate and

151 l network that regulates axial patterning in deuterostomes is evolutionarily conserved.

152 knowledge of TLR pathway evolution in other deuterostomes is limited.

153 adult forms and confirm the hypothesis that deuterostome larvae are "swimming heads" [3].

154 lly characterized, is present throughout the deuterostome lineage but is a pseudogene in humans and o

155 drate modification of glycoconjugates in the deuterostome lineage of animals.

156 ology of the innate immune system within the deuterostome lineage of animals.

157 glec expression may be limited to animals of deuterostome lineage, coincident with the appearance of

158 or the evolution of these subclasses in the deuterostome lineage.

159 ant cell-surface molecules of animals in the deuterostome lineage.

160 ge, which includes starfish to humans in the deuterostome lineage.

161 tructure identifiable in both protostome and deuterostome lineages and that the duplication seen in v

162 as also found to be present across all major deuterostome lineages despite the apparent absence of TC

163 erged before the bifurcation of nematode and deuterostome lines.

164 at FGF signaling played an ancestral role in deuterostome mesoderm formation.

165 mportant differences between protostomes and deuterostomes mitochondrial proteins: (1) ND5, and with

166 t sea star larvae can provide a valuable new deuterostome model for the study of regeneration genetic

167 ropoda and Nemertea but are unable to reject deuterostome monophyly.

168 nstrates significant conservation throughout deuterostomes; no sequence with significant identity to

169 Among deuterostomes, only echinoderms and vertebrates produce

170 no apparent homologues in other invertebrate deuterostomes or vertebrates.

171 lateria (= Nephrozoa, namely protostomes and deuterostomes) or is a clade inside Deuterostomia.

172 enoturbellida, bringing the number of living deuterostome phyla to four.

173 to predate the divergence of protostome and deuterostome phyla.

174 ior-posterior expression patterns illuminate deuterostome phylogenetic relationships and the evolutio

175 dae), an invertebrate that diverged early in deuterostome phylogeny.

176 ordates that occupy an important position in deuterostome phylogeny.

177 Hemichordates are a deuterostome phylum, the sister group to echinoderms, an

178 fect in cytosolic extracts from invertebrate deuterostomes (phylum Echinodermata).

179 ambrian ancestor of most protostomes and the deuterostomes possessed elements of the genetic machiner

180 If so, the protostomes and deuterostomes probably shared a common segmented ancesto

181 es, the proportion of duplications after the deuterostome-protostome split was constant across famili

182 oturbella and that Xenoturbella is in fact a deuterostome related to hemichordates and echinoderms.

183 controversial and the nature of the original deuterostome remains idealized.

184 important groups, arthropods, nematodes, and deuterostomes, remains unresolved.

185 Egg activation at fertilization in deuterostomes requires a rise in intracellular Ca(2+), w

186 bly, the anterior neuroectoderm (ANE) of the deuterostome sea urchin embryo expresses many of the sam

187 nome level, as this is the first nonchordate deuterostome sequence.

188 hins is similar to that found in other basal deuterostomes, signal-responsive initiator caspase subfa

189 king in arthropod or nematode genomes may be deuterostome-specific (subclasses I, J1, J2, L1, M and Q

190 Comparative analysis reveals numerous deuterostome-specific gene novelties, including genes fo

191 Notably, hemichordates possess a deuterostome-specific genomic cluster of four ordered tr

192 y expressed bmp4 and admp genes represents a deuterostome-specific innovation.

193 invertebrates although there are significant deuterostome-specific innovations and some interesting f

194 mostly in triploblasts before the protostome-deuterostome split, whereas few subfamilies were lost in

195 that remarkably is linked to the protostome-deuterostome split.

196 Comparisons of Amphioxus with other deuterostomes suggest that patterning of the ancestral d

197 alyzing genomes and transcriptomes across 37 deuterostome taxa, we shed light on the evolution and di

198 , have significantly lower hydrophobicity in deuterostomes than in proterostomes; (2) the C-terminal

199 ovel family of neuropeptides in invertebrate deuterostomes that are derived from neurophysin-containi

200 In the sea urchin, a prototypic deuterostome, the ectoderm-endoderm boundary is establis

201 chozoan shares with an indirectly developing deuterostome, the sea urchin, a common mode of Hox compl

202 RH-type and CRZ-type signalling systems in a deuterostome-the echinoderm (starfish) Asterias rubens.

203 characteristics with vertebrates, including deuterostome type development.

204 and mechanisms of mesoderm specification in deuterostomes unclear.

205 roides genome content with distantly related deuterostomes (urchins, sea squirts, and humans) suggest

206 ndamental body plan within a basal phylum of deuterostomes was enteropneust-like.

207 to the mouth and anus of the protostomes and deuterostomes, we studied the expression of genes involv

208 y complex members of astacin-type enzymes in deuterostomes, which can add supporting data to corrobor

209 o argue that the foreguts of protostomes and deuterostomes, which have traditionally been assigned to

210 f larger extra-membrane hydrophilic loops in deuterostomes with respect to protostomes; (3) substitut