ライフサイエンスコーパス: devastate

1 sult of injuries to the prefrontal cortex is devastating.

2 atin therapy is stopped unnecessarily can be devastating.

3 Their loss in Parkinson's disease is devastating.

4 densities their environmental impacts can be devastating.

5 influenza A viruses (IAVs) that approach the devastating 1918 strain motivates finding strain-specifi

6 The devastating 2004 Indian Ocean tsunami caught millions of

7 Amyotrophic lateral sclerosis (ALS) is a devastating adult-onset neurodegenerative disorder with

8 Intracerebral hemorrhage (ICH) is the most devastating adverse event in patients receiving oral ant

9 rmigera Hubner (Lepidoptera: Noctuidae) is a devastating agricultural insect pest with broad spectrum

10 me of its rare complications are potentially devastating and are difficult to diagnose early.

11 Chronic wounds are among the most devastating and difficult to treat consequences of diabe

12 cerebral hemorrhage (ICH) is one of the most devastating and disabling forms of stroke, yet effective

13 e cassava immune system, thus making it more devastating and harder to control.

14 Amyotrophic lateral sclerosis (ALS) is a devastating and incurable neurodegenerative disease, cha

15 Child abuse has devastating and long-lasting consequences, considerably

16 al effects of penile loss in a young man are devastating and replacing it with the same organ is like

17 erica in 2015 and its causal relationship to devastating anomalies in newborn infants.

18 ly progressive neurodegenerative disease, as devastating as childhood cerebral adrenoleukodystrophy.

19 ne result in severe enzymatic deficiency and devastating autonomic, motor, and cognitive impairment,

20 he Xa21 gene have enhanced resistant to most devastating bacterial blight diseases caused by Xanthomo

21 into the causes and prevention of a suite of devastating birth defects, as well as basic evolutionary

22 essive dystrophic epidermolysis bullosa is a devastating blistering disease caused by mutations in th

23 Myelofibrosis (MF) is a devastating blood disorder.

24 hway from patients who died as a result of a devastating brain injury (possible donors) in 68 hospita

25 Pain places a devastating burden on patients and society and current p

26 No light perception is a devastating but uncommon outcome of B-KPro surgery.

27 me regions of West Africa that were recently devastated by Ebola.

28 uropean Ash tree Fraxinus excelsior is being devastated by the fungal pathogen Hymenoscyphus fraxineu

29 ative agent of witches' broom disease, which devastates cacao cultures in South America.

30 ted as a therapeutic strategy to fight these devastating cancers.

31 is now used clinically to treat a variety of devastating cancers.

32 ss has been tempered by unintended and often devastating cardiac complications affecting overall pati

33 In particular, white band disease (WBD) has devastated Caribbean acroporid populations since its ini

34 Porcine epidemic diarrhea virus (PEDV) is a devastating cause of diarrhea in pigs worldwide.

35 Traumatic optic neuropathy (TON) is a devastating cause of permanent visual loss following blu

36 Hunter syndrome is a rare but devastating childhood disease caused by mutations in the

37 muscular atrophy (SMA), the most common and devastating childhood genetic motor-neuron disease.

38 Periprosthetic joint infections are a devastating complication after arthroplasty and are asso

39 Perioperative bleeding is a potentially devastating complication in neurosurgical patients, and

40 d by loss of proteins in the intestine, is a devastating complication in patients with congenital hea

41 sease (aGVHD) continues to be a frequent and devastating complication of allogeneic hematopoietic ste

42 Coccidioidal meningitis (CM) is a devastating complication of coccidioidomycosis.

43 Importance: Diabetic retinopathy (DR) is a devastating complication of individuals with type 2 diab

44 ceptor in the neonatal lung may prevent this devastating complication of NEC.

45 us system (CNS) relapses are an uncommon yet devastating complication of non-Hodgkin lymphomas.

46 e report we describe long-term outcomes of a devastating complication of ophthalmic artery emboli fol

47 Preeclampsia is a devastating complication of pregnancy.

48 ction without additional glaucoma surgery or devastating complication.

49 , P = .048), and had comparable incidence of devastating complications (P = .065).

50 TBN is one of the most devastating complications of caustic ingestion.

51 kines are best targeted to slow/reverse this devastating condition in cancer patients.

52 While the mainstay of treatment for this devastating condition remains largely supportive, resear

53 s acute graft-versus-host disease (aGVHD), a devastating condition that arises when donor T cells att

54 ve retinal vasculitis is a rare, potentially devastating condition that can develop after cataract su

55 Postoperative HORV is a devastating condition that can occur after otherwise unc

56 acute liver failure (PALF) is a potentially devastating condition that occurs in previously healthy

57 Neonatal herpes is a rare but potentially devastating condition with an estimated 60% fatality rat

58 Treatment-refractory depression is a devastating condition with significant morbidity, mortal

59 ively little attention has been paid to this devastating condition, and the bulk of research is limit

60 f new potential therapeutic targets for this devastating condition.

61 (ZIKV) infection during pregnancy can cause devastating congenital abnormities or fetal demise.

62 mostly causes mild disease, but is linked to devastating congenital birth defects and Guillain-Barre

63 (ZIKV), a mosquito-borne flavivirus, causes devastating congenital birth defects.

64 ama2-related muscular dystrophy (MDC1A) is a devastating congenital muscular dystrophy caused by muta

65 conjunctival myxoma can prevent potentially devastating consequences (Ophthalmic Surg Lasers Imaging

66 hronic methamphetamine use poses potentially devastating consequences for directly affected individua

67 a serious public health problem, often with devastating consequences for patients and their families

68 changes in sodium channel activity can have devastating consequences for the function of the nervous

69 l artery occlusion is a rare occurrence with devastating consequences if missed on imaging.

70 nt paediatric brain tumour, often inflicting devastating consequences on the developing child.

71 Immunogenicity can have devastating consequences on the safety and efficacy of t

72 Neuronal injury often leads to devastating consequences such as loss of senses or locom

73 mpowerment for health (self-preservation for devastating consequences, self-advocacy and education, n

74 ocesses align to drive intense heating, with devastating consequences.

75 y lead to inappropriate decision-making with devastating consequences.

76 Diabrotica virgifera virgifera LeConte) is a devastating crop pest in North America and Europe.

77 for cancer therapy by discriminating against devastating cytotoxicity of chemotherapeutic drugs to he

78 In medical settings, biofilms cause devastating damage during chronic and acute infections;

79 Ataxia is a progressive and devastating degenerative movement disorder commonly asso

80 The deletion of Pax6 results in devastated development of eye, olfactory bulb, and corte

81 formations of the cerebral cortex (MCCs) are devastating developmental disorders.

82 Cholera is a devastating diarrhoeal disease caused by certain strains

83 model with "humanized" telomere lengths, the devastating dilated cardiomyopathy phenotype seen in pat

84 y toward recurrent, unprovoked seizures-is a devastating disease affecting 65 million people worldwid

85 NCE Foot-and-mouth disease (FMD) is the most devastating disease affecting livestock worldwide.

86 ion so that agents to prevent and treat this devastating disease can be rapidly developed and studied

87 Alzheimer's disease is a common and devastating disease characterized by aggregation of the

88 Small cell lung cancer (SCLC) is a devastating disease due to its propensity for early inva

89 Cholangiocarcinoma (CCA) is a devastating disease due to no effective treatments avail

90 Many enveloped viruses cause devastating disease in aquaculture, resulting in signifi

91 Rift Valley fever virus (RVFV), which causes devastating disease in both humans and animals.

92 e elimination of a medically and financially devastating disease in dogs and further understanding of

93 family with nine different serotypes, causes devastating disease in equids.

94 ly effective treatment for malaria, the most devastating disease in human history.

95 However, the etiopathogenesis of this devastating disease is not fully understood.

96 lead to a true reversal of this potentially devastating disease of ageing.

97 This virus causes an economically devastating disease of livestock affecting both the deve

98 virus (NDV) cause Newcastle disease (ND), a devastating disease of poultry and wild birds.

99 (FHB), caused by Fusarium graminearum, is a devastating disease of wheat and barley that leads to re

100 h century pandemic of Yersinia pestis caused devastating disease outbreaks in Europe for almost 400 y

101 rogress in understanding the complexity of a devastating disease such as cancer has underscored the n

102 Schizophrenia is a devastating disease that arises on the background of gen

103 Idiopathic pulmonary fibrosis (IPF) is a devastating disease that remains refractory to current t

104 Stroke is a devastating disease with an increasing prevalence.

105 ic obstructive pulmonary disease (COPD) is a devastating disease with no effective therapies.

106 Crescentic glomerulonephritis (GN) is a devastating disease with rapidly progressive deteriorati

107 Intracerebral hemorrhage (ICH) is a devastating disease without effective treatment.

108 urrent arsenal of drugs for this potentially devastating disease, and what the future holds.

109 anostics may bring to the fight against this devastating disease, further rigorous research is warran

110 Idiopathic pulmonary fibrosis is a devastating disease, with no good diagnostic biomarker a

111 utmost importance for the treatment of this devastating disease, yet effective strategies remain elu

112 chanisms-promises new insights to treat this devastating disease.

113 further discover the pathomechanisms of this devastating disease.

114 eramide may be a therapeutic target for this devastating disease.

115 Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease.

116 ltigene transgenic cassettes to control this devastating disease.

117 apies that can delay the progression of this devastating disease.

118 n lysosomal cystine depletion alone for this devastating disease.

119 at provide promise for the treatment of this devastating disease.

120 iding a new tool to facilitate studying this devastating disease.

121 is known about how XPG loss results in this devastating disease.

122 the cognitive deficits associated with this devastating disease.

123 ng efficacious drug candidates to treat this devastating disease.

124 arvicide distributed worldwide to combat the devastating diseases borne by mosquitoes.

125 rosis without any obvious cause, such as the devastating diseases idiopathic pulmonary fibrosis (IPF)

126 eaf curl viruses (CLCuVs), is among the most devastating diseases in cotton.

127 lity.IMPORTANCE Smallpox was one of the most devastating diseases in human history until it was eradi

128 cess, and their deregulated signaling causes devastating diseases manifested by severe acute or chron

129 er" species are associated with economically devastating diseases of citrus, potato, and many other c

130 The devastating diseases of human cancer are mimicked in bas

131 P signaling implicated in the development of devastating diseases such as chronic pain and cancer.

132 In trypanosomatids, etiological agents of devastating diseases, replication is robust and finely c

133 f the pathogenic mechanisms of ALS and other devastating diseases.

134 te drugs as potential therapeutics for these devastating diseases.

135 inflammation, initiating progression of many devastating diseases.

136 lagellate protists including some that cause devastating diseases.

137 SZ remains a devastating disorder despite treatment.

138 d to as "trigger sounds") makes misophonia a devastating disorder for sufferers and their families, a

139 Postinjury epilepsy is an unpreventable and devastating disorder that develops following brain injur

140 Intracerebral hemorrhage is a devastating disorder with no current treatment.

141 to the critical need for treatments for this devastating disorder, optimism for developing RTT treatm

142 e related to neurocognitive problems in this devastating disorder.

143 re essential to improve the outcome of these devastating disorders.

144 rstanding on the molecular features of these devastating disorders.

145 or future therapeutic interventions in these devastating disorders.

146 myelitis is a major problem worldwide and is devastating due to the potential for limb-threatening se

147 alian Apennines, where crustal extension and devastating earthquakes occur in response to regional su

148 health concern, as exemplified by the recent devastating Ebola virus (EBOV) outbreak.

149 off these threats, which otherwise can have devastating ecological and economic consequences on ecos

150 ises and aims to eliminate these potentially devastating economic effects.

151 Canine parvovirus (CPV) outbreaks can have a devastating effect in communities with dense dog populat

152 s that is so urgently needed to overcome the devastating effect of fungal diseases.

153 Climate change could have a devastating effect on human and environmental health.

154 ds healing by secondary intention can have a devastating effect on patients, both physical and psycho

155 y Mycobacterium tuberculosis (Mtb) has had a devastating effect on the world population.

156 an important role to play in mitigating the devastating effects of human trafficking on individuals

157 ntial therapeutic approaches to decrease the devastating effects of MS and other inflammatory disease

158 is an urgent public health problem that has devastating effects on maternal and child health.

159 nts through adaptive evolution, resulting in devastating effects on native communities.

160 t alter the amplitude of these currents have devastating effects on neuronal development and function

161 (KCNT1) Na(+)-activated K(+) current produce devastating effects on neuronal development and neuronal

162 Lewis discuss marine microplastics and their devastating effects on ocean ecosystems.

163 oduced in 2010 into Haiti, where it caused a devastating epidemic.

164 ction-related epilepsy syndrome (FIRES) is a devastating epileptic encephalopathy with limited treatm

165 Sudden cardiac death (SCD) is a devastating event afflicting 350 000 Americans annually

166 ly being used for terrorist attacks to cause devastating explosions.

167 arget of rapamycin (mTOR) contributes to the devastating features of cancer cells.

168 s (ZIKV) infection during pregnancy leads to devastating fetal outcomes, including intrauterine growt

169 Systemic sclerosis (scleroderma, SSc) is a devastating fibrotic disease with few treatment options.

170 hytopathogen Erwinia amylovora, the cause of devastating fire blight disease in apple and pear, have

171 rus infection of humans and livestock can be devastating for individuals and populations, sometimes r

172 orm (SBW, Choristoneura fumiferana) the most devastating forest insect of eastern North America in co

173 Intracerebral hemorrhage (ICH) is a devastating form of stroke that results from the rupture

174 The most devastating form of the disease is cerebral malaria, whi

175 Tuberculous meningitis (TBM) is the most devastating form of tuberculosis, yet very little is kno

176 As one of the most devastating forms of trauma, spinal cord injury (SCI) re

177 tritici (Pgt) causes wheat stem rust, a devastating fungal disease.

178 Acute pancreatitis (AP) is a common and devastating gastrointestinal disorder that causes signif

179 We focused on Usher syndrome, a devastating genetic disorder that causes blindness, bala

180 High-grade gliomas (HGG) are a devastating group of cancers, and represent the leading

181 Epileptic encephalopathies are a devastating group of severe childhood onset epilepsies w

182 Ebola virus causes devastating hemorrhagic fever outbreaks for which no app

183 ophagous female mosquitoes transmit numerous devastating human diseases, including malaria, dengue fe

184 Members of the genus Mycobacterium cause devastating human diseases, including tuberculosis.

185 and Mycobacterium tuberculosis, which cause devastating human diseases.

186 Depression is a common, devastating illness.

187 d injury (RCI) has become a real threat with devastating immunosuppression.

188 tivating mutations in their genes and by the devastating impact caused by such mutations on normal de

189 foundly disabling psychiatric illness with a devastating impact not only upon the afflicted but also

190 h cardiovascular mortality has declined, the devastating impact of chronic heart disease and comorbid

191 Our results demonstrate a potentially devastating impact of Disc1 deficiency on neural circuit

192 Despite the devastating impact of microbial infections on the develo

193 l environmental factors, but the potentially devastating impact of volcanic activity has not been con

194 rus (ZIKV) infection in the Americas and its devastating impact on fetal development have prompted th

195 ed a reasonable target for avoiding the most devastating impacts of anthropogenic climate change.

196 rred frequently around the world, and caused devastating impacts on crop yields and water supply.

197 ghout the Northern Hemisphere, but are being devastated in Europe by the fungus Hymenoscyphus fraxine

198 ational approaches to prevent or treat these devastating infections.

199 the late fifteenth century established this devastating infectious disease as one of the most feared

200 able to work towards new medicines to treat devastating infectious diseases, and use bacteria to und

201 Acute pancreatitis (AP) is a common and devastating inflammatory condition of the pancreas that

202 iple organ dysfunction syndrome (AP-MODS); a devastating inflammatory condition with a mortality rate

203 X-linked adrenoleukodystrophy (ALD) is a devastating inherited neurodegenerative disease caused b

204 ivity these channels are sufficient to cause devastating inherited neurological diseases, such as epi

205 Pulmonary fibrosis is a kind of devastating interstitial lung disease due to the limited

206 Necrotizing enterocolitis (NEC) is a devastating intestinal disease that has been associated

207 Colorado Potato Beetle (CPB) is a devastating invasive pest of potato both in its native N

208 radic amyotrophic lateral sclerosis (ALS), a devastating, late-onset motor neuronal disease, with mor

209 ycobacterium tuberculosis continues to cause devastating levels of mortality due to tuberculosis (TB)

210 Cholangiocarcinoma (CCA) is a devastating liver tumour arising from malignant transfor

211 -mouth disease (FMD) remains one of the most devastating livestock diseases around the world.

212 Acquired epilepsy is a devastating long-term risk of various brain insults, inc

213 en Revolution caused chaos in irrigation and devastating losses from pests.

214 namental crops that must be managed to avoid devastating losses.

215 Idiopathic pulmonary fibrosis is a devastating lung disease with limited treatment options.

216 Idiopathic pulmonary fibrosis (IPF) is a devastating lung disorder with increasing incidence.

217 Its absence leads to devastating lymphoproliferation and autoimmunity in scur

218 Glioblastoma (GBM) is a devastating malignancy with few therapeutic options.

219 Sudden cardiac death (SCD) is the most devastating manifestation of ventricular arrhythmias (VA

220 Female genital fistula is a devastating maternal complication of delivery in develop

221 ritical role of this protein in a variety of devastating mental illnesses.

222 Cancer cachexia is a devastating metabolic syndrome characterized by systemic

223 pus erythematosus, rheumatoid arthritis, and devastating monogenic disorders (interferonopathies) cha

224 ia, caused by the protozoan Plasmodium, is a devastating mosquito-borne disease with the potential to

225 proposed as a tool to block transmission of devastating mosquito-borne infectious diseases like deng

226 disorder of glycosylation type 1a (CDG1A), a devastating multisystem disorder with prominent neurolog

227 scular dystrophy is a slowly progressive but devastating myopathy caused by loss of repression of the

228 orts to reduce the population burden of this devastating neonatal disease.

229 rized by memory loss, cognitive decline, and devastating neurodegeneration, not only as a result of t

230 ents to better manage antioxidant therapy in devastating neurodegenerative and neurodevelopmental dis

231 ew opportunities for finding a cure for this devastating neurodegenerative disease.

232 Alzheimer's disease is one of the most devastating neurodegenerative diseases without effective

233 and is genetically linked to two common and devastating neurodegenerative diseases.

234 NCE STATEMENT: Alzheimer's disease (AD) is a devastating neurodegenerative disorder and there are cur

235 Cerebral X-linked adrenoleukodystrophy is a devastating neurodegenerative disorder caused by mutatio

236 Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by

237 Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder in which the loss

238 pathogenesis of Huntington's disease (HD), a devastating neurodegenerative disorder, how proteasome a

239 lar cell inclusions is linked to a number of devastating neurodegenerative disorders collectively kno

240 Prion diseases are devastating neurodegenerative disorders with no known cu

241 ons in the CLN1 gene, encoding PPT1, cause a devastating neurodegenerative LSD, INCL.

242 ission and prevent disease, particularly the devastating neurodevelopmental defects that occur in ute

243 Small cell lung cancer (SCLC) is a devastating neuroendocrine carcinoma.

244 ctions (TFESIs) are associated with rare but devastating neurologic complications.

245 rogressive cerebral demyelination and rapid, devastating neurologic decline.

246 Friedreich's ataxia is a devastating neurological disease currently lacking any p

247 associated acute flaccid myelitis (AFM) is a devastating neurological disease for which there are no

248 th severe clinical manifestations, including devastating neurological disease in infants.

249 model has long generated insights into this devastating neurological disease state.

250 that cell therapy may offer a cure for this devastating neurological disease.

251 NIFICANCE STATEMENTSCN8A encephalopathy is a devastating neurological disorder that results from de n

252 his will both tell us more about potentially devastating neurological disorders and extend our unders

253 The devastating neurological impairments that result from bl

254 Spinal muscular atrophy (SMA) is a devastating neuromuscular disorder characterized by loss

255 erior ischemic optic neuropathy (NAION) is a devastating ocular condition causing permanent vision lo

256 c epidermal necrolysis remain among the most devastating of acute conditions involving the skin.

257 Phytophthora palmivora is a devastating oomycete plant pathogen.

258 Barre syndrome, congenital microcephaly, and devastating ophthalmologic and neurologic developmental

259 The recent devastating outbreak of Zika virus in Brazil was precede

260 c environmental determinants responsible for devastating outbreaks in several communities in the stat

261 Many of the devastating pandemics and outbreaks of the 20th and 21st

262 sion of influenza A viruses can give rise to devastating pandemics, but currently it is impossible to

263 Here we show how this devastating pathogen evolved in Brazil.

264 ssential proteins in the lytic cycle of this devastating pathogen.

265 is constantly threatened by the presence of devastating pathogens worldwide.

266 Alveolar rhabdomyosarcoma (ARMS) is a devastating pediatric disease driven by expression of th

267 RVFV has caused large, devastating periodic epizootics and epidemics in Africa

268 e fall armyworm (Spodoptera frugiperda) is a devastating pest of corn in the Western Hemisphere initi

269 The brown planthopper (BPH) is a devastating pest of rice throughout Asia.

270 ato weevil Cylas brunneus is one of the most devastating pests affecting the production of sweetpotat

271 e causal agent of pine wilt disease that has devastated pine forests in Asia.

272 cyst nematode, Globodera rostochiensis, is a devastating plant pathogen of global economic importance

273 gal class Dothideomycetes, a class known for devastating plant pathogens.

274 ion of classical swine fever virus (CSFV), a devastating porcine pestivirus.

275 cus aureus is a human commensal but also has devastating potential as an opportunistic pathogen.

276 Concussions carry devastating potential for cognitive, neurologic, and soc

277 Pancreatic cancer has a devastating prognosis, with an overall 5-year survival r

278 ion and how their metastability may underlie devastating protein aggregation diseases.

279 Anorexia nervosa (AN) is a devastating psychiatric illness that is associated with

280 Schizophrenia is a devastating psychiatric illness with high heritability.

281 Schizophrenia, a devastating psychiatric illness with onset in the late t

282 Plasmodium falciparum malaria remains a devastating public health problem.

283 peripheral nerve sheath tumors (MPNSTs) are devastating sarcomas for which no effective medical ther

284 Postinjury epilepsy (PIE) is a devastating sequela of various brain insults.

285 March 2011, the Great East Japan Earthquake devastated several power stations and caused severe elec

286 nalyses of the mechanisms that underlie this devastating side effect of anti-cancer therapy.

287 epidemic of prescription drug abuse and its devastating socioeconomic impacts on public health.

288 Tropical cyclones (TCs) can have devastating socioeconomic impacts.

289 r accumulation is synchronized with the most devastating stage of SBW.

290 Chronic, persistent itch is a devastating symptom that causes much suffering.

291 Cachexia is a devastating syndrome that causes morbidity and mortality

292 our disease (DFTD) is a transmissible cancer devastating the Tasmanian devil (Sarcophilus harrisii) p

293 Outbreaks of the disease are devastating to the swine industry and are caused by circ

294 etence of the eye, a fact underscored by the devastating toll of excessive inflammation at the cornea

295 at effective therapies are imminent for this devastating transplant complication.

296 environment continues to be associated with devastating vascular complications in diabetes despite c

297 The unprecedented Ebola outbreak that devastated West Africa evolved within months from a regi

298 spread sustainably among people and cause a devastating worldwide pandemic.

299 nown as river blindness - is one of the most devastating yet neglected tropical diseases, leaving man

300 Striga asiatica and Striga hermonthica cause devastating yield losses to upland rice in Africa.