ライフサイエンスコーパス: devastating

1 sult of injuries to the prefrontal cortex is devastating.

2 atin therapy is stopped unnecessarily can be devastating.

3 Their loss in Parkinson's disease is devastating.

4 densities their environmental impacts can be devastating.

5 influenza A viruses (IAVs) that approach the devastating 1918 strain motivates finding strain-specifi

6 The devastating 2004 Indian Ocean tsunami caught millions of

7 Amyotrophic lateral sclerosis (ALS) is a devastating adult-onset neurodegenerative disorder with

8 Intracerebral hemorrhage (ICH) is the most devastating adverse event in patients receiving oral ant

9 rmigera Hubner (Lepidoptera: Noctuidae) is a devastating agricultural insect pest with broad spectrum

10 me of its rare complications are potentially devastating and are difficult to diagnose early.

11 Chronic wounds are among the most devastating and difficult to treat consequences of diabe

12 cerebral hemorrhage (ICH) is one of the most devastating and disabling forms of stroke, yet effective

13 e cassava immune system, thus making it more devastating and harder to control.

14 Amyotrophic lateral sclerosis (ALS) is a devastating and incurable neurodegenerative disease, cha

15 Child abuse has devastating and long-lasting consequences, considerably

16 al effects of penile loss in a young man are devastating and replacing it with the same organ is like

17 erica in 2015 and its causal relationship to devastating anomalies in newborn infants.

18 ly progressive neurodegenerative disease, as devastating as childhood cerebral adrenoleukodystrophy.

19 ne result in severe enzymatic deficiency and devastating autonomic, motor, and cognitive impairment,

20 he Xa21 gene have enhanced resistant to most devastating bacterial blight diseases caused by Xanthomo

21 into the causes and prevention of a suite of devastating birth defects, as well as basic evolutionary

22 essive dystrophic epidermolysis bullosa is a devastating blistering disease caused by mutations in th

23 Myelofibrosis (MF) is a devastating blood disorder.

24 hway from patients who died as a result of a devastating brain injury (possible donors) in 68 hospita

25 Pain places a devastating burden on patients and society and current p

26 No light perception is a devastating but uncommon outcome of B-KPro surgery.

27 ted as a therapeutic strategy to fight these devastating cancers.

28 is now used clinically to treat a variety of devastating cancers.

29 ss has been tempered by unintended and often devastating cardiac complications affecting overall pati

30 Porcine epidemic diarrhea virus (PEDV) is a devastating cause of diarrhea in pigs worldwide.

31 Traumatic optic neuropathy (TON) is a devastating cause of permanent visual loss following blu

32 Hunter syndrome is a rare but devastating childhood disease caused by mutations in the

33 muscular atrophy (SMA), the most common and devastating childhood genetic motor-neuron disease.

34 Periprosthetic joint infections are a devastating complication after arthroplasty and are asso

35 Perioperative bleeding is a potentially devastating complication in neurosurgical patients, and

36 d by loss of proteins in the intestine, is a devastating complication in patients with congenital hea

37 sease (aGVHD) continues to be a frequent and devastating complication of allogeneic hematopoietic ste

38 Coccidioidal meningitis (CM) is a devastating complication of coccidioidomycosis.

39 Importance: Diabetic retinopathy (DR) is a devastating complication of individuals with type 2 diab

40 ceptor in the neonatal lung may prevent this devastating complication of NEC.

41 us system (CNS) relapses are an uncommon yet devastating complication of non-Hodgkin lymphomas.

42 e report we describe long-term outcomes of a devastating complication of ophthalmic artery emboli fol

43 Preeclampsia is a devastating complication of pregnancy.

44 ction without additional glaucoma surgery or devastating complication.

45 , P = .048), and had comparable incidence of devastating complications (P = .065).

46 TBN is one of the most devastating complications of caustic ingestion.

47 kines are best targeted to slow/reverse this devastating condition in cancer patients.

48 While the mainstay of treatment for this devastating condition remains largely supportive, resear

49 s acute graft-versus-host disease (aGVHD), a devastating condition that arises when donor T cells att

50 ve retinal vasculitis is a rare, potentially devastating condition that can develop after cataract su

51 Postoperative HORV is a devastating condition that can occur after otherwise unc

52 acute liver failure (PALF) is a potentially devastating condition that occurs in previously healthy

53 Neonatal herpes is a rare but potentially devastating condition with an estimated 60% fatality rat

54 Treatment-refractory depression is a devastating condition with significant morbidity, mortal

55 ively little attention has been paid to this devastating condition, and the bulk of research is limit

56 f new potential therapeutic targets for this devastating condition.

57 (ZIKV) infection during pregnancy can cause devastating congenital abnormities or fetal demise.

58 mostly causes mild disease, but is linked to devastating congenital birth defects and Guillain-Barre

59 (ZIKV), a mosquito-borne flavivirus, causes devastating congenital birth defects.

60 ama2-related muscular dystrophy (MDC1A) is a devastating congenital muscular dystrophy caused by muta

61 Brain metastases (BM) are a devastating consequence of breast cancer.

62 conjunctival myxoma can prevent potentially devastating consequences (Ophthalmic Surg Lasers Imaging

63 hronic methamphetamine use poses potentially devastating consequences for directly affected individua

64 a serious public health problem, often with devastating consequences for patients and their families

65 changes in sodium channel activity can have devastating consequences for the function of the nervous

66 l artery occlusion is a rare occurrence with devastating consequences if missed on imaging.

67 nt paediatric brain tumour, often inflicting devastating consequences on the developing child.

68 Immunogenicity can have devastating consequences on the safety and efficacy of t

69 Neuronal injury often leads to devastating consequences such as loss of senses or locom

70 mpowerment for health (self-preservation for devastating consequences, self-advocacy and education, n

71 ocesses align to drive intense heating, with devastating consequences.

72 y lead to inappropriate decision-making with devastating consequences.

73 Diabrotica virgifera virgifera LeConte) is a devastating crop pest in North America and Europe.

74 for cancer therapy by discriminating against devastating cytotoxicity of chemotherapeutic drugs to he

75 In medical settings, biofilms cause devastating damage during chronic and acute infections;

76 d by ingesting plant and animal fluids cause devastating damage to humans, livestock, and agriculture

77 Ataxia is a progressive and devastating degenerative movement disorder commonly asso

78 lack of cholesterol production leads to the devastating developmental disorder, Smith-Lemli-Opitz sy

79 formations of the cerebral cortex (MCCs) are devastating developmental disorders.

80 Cholera is a devastating diarrhoeal disease caused by certain strains

81 model with "humanized" telomere lengths, the devastating dilated cardiomyopathy phenotype seen in pat

82 y toward recurrent, unprovoked seizures-is a devastating disease affecting 65 million people worldwid

83 Duchenne muscular dystrophy (DMD) is a devastating disease affecting about 1 out of 5000 male b

84 NCE Foot-and-mouth disease (FMD) is the most devastating disease affecting livestock worldwide.

85 ion so that agents to prevent and treat this devastating disease can be rapidly developed and studied

86 Alzheimer's disease is a common and devastating disease characterized by aggregation of the

87 Small cell lung cancer (SCLC) is a devastating disease due to its propensity for early inva

88 Cholangiocarcinoma (CCA) is a devastating disease due to no effective treatments avail

89 Many enveloped viruses cause devastating disease in aquaculture, resulting in signifi

90 Rift Valley fever virus (RVFV), which causes devastating disease in both humans and animals.

91 e elimination of a medically and financially devastating disease in dogs and further understanding of

92 family with nine different serotypes, causes devastating disease in equids.

93 ly effective treatment for malaria, the most devastating disease in human history.

94 However, the etiopathogenesis of this devastating disease is not fully understood.

95 lead to a true reversal of this potentially devastating disease of ageing.

96 This virus causes an economically devastating disease of livestock affecting both the deve

97 virus (NDV) cause Newcastle disease (ND), a devastating disease of poultry and wild birds.

98 (FHB), caused by Fusarium graminearum, is a devastating disease of wheat and barley that leads to re

99 h century pandemic of Yersinia pestis caused devastating disease outbreaks in Europe for almost 400 y

100 rogress in understanding the complexity of a devastating disease such as cancer has underscored the n

101 Schizophrenia is a devastating disease that arises on the background of gen

102 Idiopathic pulmonary fibrosis (IPF) is a devastating disease that remains refractory to current t

103 Stroke is a devastating disease with an increasing prevalence.

104 ic obstructive pulmonary disease (COPD) is a devastating disease with no effective therapies.

105 Crescentic glomerulonephritis (GN) is a devastating disease with rapidly progressive deteriorati

106 Intracerebral hemorrhage (ICH) is a devastating disease without effective treatment.

107 urrent arsenal of drugs for this potentially devastating disease, and what the future holds.

108 anostics may bring to the fight against this devastating disease, further rigorous research is warran

109 Idiopathic pulmonary fibrosis is a devastating disease, with no good diagnostic biomarker a

110 utmost importance for the treatment of this devastating disease, yet effective strategies remain elu

111 further discover the pathomechanisms of this devastating disease.

112 eramide may be a therapeutic target for this devastating disease.

113 Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease.

114 ltigene transgenic cassettes to control this devastating disease.

115 apies that can delay the progression of this devastating disease.

116 n lysosomal cystine depletion alone for this devastating disease.

117 at provide promise for the treatment of this devastating disease.

118 iding a new tool to facilitate studying this devastating disease.

119 is known about how XPG loss results in this devastating disease.

120 the cognitive deficits associated with this devastating disease.

121 ng efficacious drug candidates to treat this devastating disease.

122 chanisms-promises new insights to treat this devastating disease.

123 arvicide distributed worldwide to combat the devastating diseases borne by mosquitoes.

124 rosis without any obvious cause, such as the devastating diseases idiopathic pulmonary fibrosis (IPF)

125 eaf curl viruses (CLCuVs), is among the most devastating diseases in cotton.

126 lity.IMPORTANCE Smallpox was one of the most devastating diseases in human history until it was eradi

127 cess, and their deregulated signaling causes devastating diseases manifested by severe acute or chron

128 er" species are associated with economically devastating diseases of citrus, potato, and many other c

129 The devastating diseases of human cancer are mimicked in bas

130 P signaling implicated in the development of devastating diseases such as chronic pain and cancer.

131 In trypanosomatids, etiological agents of devastating diseases, replication is robust and finely c

132 f the pathogenic mechanisms of ALS and other devastating diseases.

133 te drugs as potential therapeutics for these devastating diseases.

134 inflammation, initiating progression of many devastating diseases.

135 lagellate protists including some that cause devastating diseases.

136 SZ remains a devastating disorder despite treatment.

137 d to as "trigger sounds") makes misophonia a devastating disorder for sufferers and their families, a

138 Postinjury epilepsy is an unpreventable and devastating disorder that develops following brain injur

139 Intracerebral hemorrhage is a devastating disorder with no current treatment.

140 to the critical need for treatments for this devastating disorder, optimism for developing RTT treatm

141 e related to neurocognitive problems in this devastating disorder.

142 re essential to improve the outcome of these devastating disorders.

143 rstanding on the molecular features of these devastating disorders.

144 or future therapeutic interventions in these devastating disorders.

145 myelitis is a major problem worldwide and is devastating due to the potential for limb-threatening se

146 alian Apennines, where crustal extension and devastating earthquakes occur in response to regional su

147 health concern, as exemplified by the recent devastating Ebola virus (EBOV) outbreak.

148 off these threats, which otherwise can have devastating ecological and economic consequences on ecos

149 ises and aims to eliminate these potentially devastating economic effects.

150 Canine parvovirus (CPV) outbreaks can have a devastating effect in communities with dense dog populat

151 s that is so urgently needed to overcome the devastating effect of fungal diseases.

152 Climate change could have a devastating effect on human and environmental health.

153 ds healing by secondary intention can have a devastating effect on patients, both physical and psycho

154 y Mycobacterium tuberculosis (Mtb) has had a devastating effect on the world population.

155 an important role to play in mitigating the devastating effects of human trafficking on individuals

156 ntial therapeutic approaches to decrease the devastating effects of MS and other inflammatory disease

157 is an urgent public health problem that has devastating effects on maternal and child health.

158 nts through adaptive evolution, resulting in devastating effects on native communities.

159 t alter the amplitude of these currents have devastating effects on neuronal development and function

160 (KCNT1) Na(+)-activated K(+) current produce devastating effects on neuronal development and neuronal

161 Lewis discuss marine microplastics and their devastating effects on ocean ecosystems.

162 oduced in 2010 into Haiti, where it caused a devastating epidemic.

163 ction-related epilepsy syndrome (FIRES) is a devastating epileptic encephalopathy with limited treatm

164 Sudden cardiac death (SCD) is a devastating event afflicting 350 000 Americans annually

165 ly being used for terrorist attacks to cause devastating explosions.

166 arget of rapamycin (mTOR) contributes to the devastating features of cancer cells.

167 s (ZIKV) infection during pregnancy leads to devastating fetal outcomes, including intrauterine growt

168 Systemic sclerosis (scleroderma, SSc) is a devastating fibrotic disease with few treatment options.

169 hytopathogen Erwinia amylovora, the cause of devastating fire blight disease in apple and pear, have

170 rus infection of humans and livestock can be devastating for individuals and populations, sometimes r

171 orm (SBW, Choristoneura fumiferana) the most devastating forest insect of eastern North America in co

172 Intracerebral hemorrhage (ICH) is a devastating form of stroke that results from the rupture

173 The most devastating form of the disease is cerebral malaria, whi

174 Tuberculous meningitis (TBM) is the most devastating form of tuberculosis, yet very little is kno

175 As one of the most devastating forms of trauma, spinal cord injury (SCI) re

176 tritici (Pgt) causes wheat stem rust, a devastating fungal disease.

177 Acute pancreatitis (AP) is a common and devastating gastrointestinal disorder that causes signif

178 We focused on Usher syndrome, a devastating genetic disorder that causes blindness, bala

179 Malaria persists as one of the most devastating global infectious diseases.

180 High-grade gliomas (HGG) are a devastating group of cancers, and represent the leading

181 Epileptic encephalopathies are a devastating group of severe childhood onset epilepsies w

182 Ebola virus causes devastating hemorrhagic fever outbreaks for which no app

183 ophagous female mosquitoes transmit numerous devastating human diseases, including malaria, dengue fe

184 Members of the genus Mycobacterium cause devastating human diseases, including tuberculosis.

185 and Mycobacterium tuberculosis, which cause devastating human diseases.

186 nd survival of Mycobacterium tuberculosis, a devastating human pathogen.

187 Depression is a common, devastating illness.

188 d injury (RCI) has become a real threat with devastating immunosuppression.

189 tivating mutations in their genes and by the devastating impact caused by such mutations on normal de

190 foundly disabling psychiatric illness with a devastating impact not only upon the afflicted but also

191 h cardiovascular mortality has declined, the devastating impact of chronic heart disease and comorbid

192 Our results demonstrate a potentially devastating impact of Disc1 deficiency on neural circuit

193 Despite the devastating impact of microbial infections on the develo

194 l environmental factors, but the potentially devastating impact of volcanic activity has not been con

195 rus (ZIKV) infection in the Americas and its devastating impact on fetal development have prompted th

196 ed a reasonable target for avoiding the most devastating impacts of anthropogenic climate change.

197 rred frequently around the world, and caused devastating impacts on crop yields and water supply.

198 ational approaches to prevent or treat these devastating infections.

199 the late fifteenth century established this devastating infectious disease as one of the most feared

200 able to work towards new medicines to treat devastating infectious diseases, and use bacteria to und

201 Bacterial endophthalmitis remains a devastating inflammatory condition associated with perma

202 Acute pancreatitis (AP) is a common and devastating inflammatory condition of the pancreas that

203 iple organ dysfunction syndrome (AP-MODS); a devastating inflammatory condition with a mortality rate

204 X-linked adrenoleukodystrophy (ALD) is a devastating inherited neurodegenerative disease caused b

205 ivity these channels are sufficient to cause devastating inherited neurological diseases, such as epi

206 Pulmonary fibrosis is a kind of devastating interstitial lung disease due to the limited

207 Necrotizing enterocolitis (NEC) is a devastating intestinal disease that has been associated

208 Colorado Potato Beetle (CPB) is a devastating invasive pest of potato both in its native N

209 radic amyotrophic lateral sclerosis (ALS), a devastating, late-onset motor neuronal disease, with mor

210 ycobacterium tuberculosis continues to cause devastating levels of mortality due to tuberculosis (TB)

211 Cholangiocarcinoma (CCA) is a devastating liver tumour arising from malignant transfor

212 -mouth disease (FMD) remains one of the most devastating livestock diseases around the world.

213 Acquired epilepsy is a devastating long-term risk of various brain insults, inc

214 en Revolution caused chaos in irrigation and devastating losses from pests.

215 namental crops that must be managed to avoid devastating losses.

216 Idiopathic pulmonary fibrosis is a devastating lung disease with limited treatment options.

217 Idiopathic pulmonary fibrosis (IPF) is a devastating lung disorder with increasing incidence.

218 Its absence leads to devastating lymphoproliferation and autoimmunity in scur

219 Glioblastoma (GBM) is a devastating malignancy with few therapeutic options.

220 Sudden cardiac death (SCD) is the most devastating manifestation of ventricular arrhythmias (VA

221 Female genital fistula is a devastating maternal complication of delivery in develop

222 ritical role of this protein in a variety of devastating mental illnesses.

223 Cancer cachexia is a devastating metabolic syndrome characterized by systemic

224 pus erythematosus, rheumatoid arthritis, and devastating monogenic disorders (interferonopathies) cha

225 ia, caused by the protozoan Plasmodium, is a devastating mosquito-borne disease with the potential to

226 proposed as a tool to block transmission of devastating mosquito-borne infectious diseases like deng

227 disorder of glycosylation type 1a (CDG1A), a devastating multisystem disorder with prominent neurolog

228 scular dystrophy is a slowly progressive but devastating myopathy caused by loss of repression of the

229 orts to reduce the population burden of this devastating neonatal disease.

230 rized by memory loss, cognitive decline, and devastating neurodegeneration, not only as a result of t

231 ents to better manage antioxidant therapy in devastating neurodegenerative and neurodevelopmental dis

232 ew opportunities for finding a cure for this devastating neurodegenerative disease.

233 Alzheimer's disease is one of the most devastating neurodegenerative diseases without effective

234 and is genetically linked to two common and devastating neurodegenerative diseases.

235 NCE STATEMENT: Alzheimer's disease (AD) is a devastating neurodegenerative disorder and there are cur

236 Cerebral X-linked adrenoleukodystrophy is a devastating neurodegenerative disorder caused by mutatio

237 Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by

238 Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder in which the loss

239 pathogenesis of Huntington's disease (HD), a devastating neurodegenerative disorder, how proteasome a

240 lar cell inclusions is linked to a number of devastating neurodegenerative disorders collectively kno

241 Prion diseases are devastating neurodegenerative disorders with no known cu

242 ons in the CLN1 gene, encoding PPT1, cause a devastating neurodegenerative LSD, INCL.

243 ission and prevent disease, particularly the devastating neurodevelopmental defects that occur in ute

244 Schizophrenia is a devastating neurodevelopmental disorder with a complex g

245 ism spectrum disorders (ASDs) are a group of devastating neurodevelopmental syndromes that affect up

246 Small cell lung cancer (SCLC) is a devastating neuroendocrine carcinoma.

247 ctions (TFESIs) are associated with rare but devastating neurologic complications.

248 rogressive cerebral demyelination and rapid, devastating neurologic decline.

249 Friedreich's ataxia is a devastating neurological disease currently lacking any p

250 associated acute flaccid myelitis (AFM) is a devastating neurological disease for which there are no

251 th severe clinical manifestations, including devastating neurological disease in infants.

252 model has long generated insights into this devastating neurological disease state.

253 that cell therapy may offer a cure for this devastating neurological disease.

254 NIFICANCE STATEMENTSCN8A encephalopathy is a devastating neurological disorder that results from de n

255 his will both tell us more about potentially devastating neurological disorders and extend our unders

256 The devastating neurological impairments that result from bl

257 Spinal muscular atrophy (SMA) is a devastating neuromuscular disorder characterized by loss

258 erior ischemic optic neuropathy (NAION) is a devastating ocular condition causing permanent vision lo

259 c epidermal necrolysis remain among the most devastating of acute conditions involving the skin.

260 Phytophthora palmivora is a devastating oomycete plant pathogen.

261 Barre syndrome, congenital microcephaly, and devastating ophthalmologic and neurologic developmental

262 The recent devastating outbreak of Zika virus in Brazil was precede

263 c environmental determinants responsible for devastating outbreaks in several communities in the stat

264 Many of the devastating pandemics and outbreaks of the 20th and 21st

265 sion of influenza A viruses can give rise to devastating pandemics, but currently it is impossible to

266 Here we show how this devastating pathogen evolved in Brazil.

267 ssential proteins in the lytic cycle of this devastating pathogen.

268 is constantly threatened by the presence of devastating pathogens worldwide.

269 Alveolar rhabdomyosarcoma (ARMS) is a devastating pediatric disease driven by expression of th

270 RVFV has caused large, devastating periodic epizootics and epidemics in Africa

271 e fall armyworm (Spodoptera frugiperda) is a devastating pest of corn in the Western Hemisphere initi

272 The brown planthopper (BPH) is a devastating pest of rice throughout Asia.

273 ato weevil Cylas brunneus is one of the most devastating pests affecting the production of sweetpotat

274 cyst nematode, Globodera rostochiensis, is a devastating plant pathogen of global economic importance

275 gal class Dothideomycetes, a class known for devastating plant pathogens.

276 ion of classical swine fever virus (CSFV), a devastating porcine pestivirus.

277 cus aureus is a human commensal but also has devastating potential as an opportunistic pathogen.

278 Concussions carry devastating potential for cognitive, neurologic, and soc

279 Pancreatic cancer has a devastating prognosis, with an overall 5-year survival r

280 ion and how their metastability may underlie devastating protein aggregation diseases.

281 Anorexia nervosa (AN) is a devastating psychiatric illness that is associated with

282 Schizophrenia is a devastating psychiatric illness with high heritability.

283 Schizophrenia, a devastating psychiatric illness with onset in the late t

284 Plasmodium falciparum malaria remains a devastating public health problem.

285 peripheral nerve sheath tumors (MPNSTs) are devastating sarcomas for which no effective medical ther

286 Postinjury epilepsy (PIE) is a devastating sequela of various brain insults.

287 nalyses of the mechanisms that underlie this devastating side effect of anti-cancer therapy.

288 epidemic of prescription drug abuse and its devastating socioeconomic impacts on public health.

289 Tropical cyclones (TCs) can have devastating socioeconomic impacts.

290 r accumulation is synchronized with the most devastating stage of SBW.

291 Chronic, persistent itch is a devastating symptom that causes much suffering.

292 Cachexia is a devastating syndrome that causes morbidity and mortality

293 our disease (DFTD) is a transmissible cancer devastating the Tasmanian devil (Sarcophilus harrisii) p

294 Outbreaks of the disease are devastating to the swine industry and are caused by circ

295 etence of the eye, a fact underscored by the devastating toll of excessive inflammation at the cornea

296 at effective therapies are imminent for this devastating transplant complication.

297 environment continues to be associated with devastating vascular complications in diabetes despite c

298 spread sustainably among people and cause a devastating worldwide pandemic.

299 nown as river blindness - is one of the most devastating yet neglected tropical diseases, leaving man

300 Striga asiatica and Striga hermonthica cause devastating yield losses to upland rice in Africa.