ライフサイエンスコーパス: develop

1 minant V2-glycan broadly neutralizing Abs to develop.

2 he pathology of LAM have been challenging to develop.

3 tanding how the wide diversity of cell types develops.

4 glycol) and methods for consolidation to be developed.

5 manuscript, two additional assays have been developed.

6 movable vicinal diamine directing groups was developed.

7 ensity of these particular GO nanosheets was developed.

8 aS)-configured decahydroquinoxalines 5-8 was developed.

9 ,3-diol in cheese and bacterial cultures was developed.

10 Here, we developed 3D cell-line-based models of human syncytiotro

11 en fluke infection, it is imperative that we develop a better understanding of the basic biology of t

12 Here we develop a biphasic hydrogel methodology, which along wit

13 y angiography, the goal of this study was to develop a clinical and biomarker score to predict the pr

14 mTORC1 or mTORC1/mTORC2 but not mTORC2 alone develop a Fanconi-like syndrome of glucosuria, phosphatu

15 Therefore, it is crucial to develop a fast and effective filter that can detect inco

16 Therefore, there is an urgent need to develop a high-throughput and efficient strategy to iden

17 We develop a mathematical model of the function of the 1,2-

18 Purpose To develop a method to incorporate the propagation of contr

19 We set out to develop a method to overcome this obstacle by utilizing

20 We aimed to develop a methodical approach that would yield a broad a

21 not achievable using traditional methods, we develop a multi-sample-based method.

22 different thin film technologies in order to develop a multifunctional platform suitable for on-chip

23 enario-based life cycle assessment (LCA), we develop a multiobjective optimization model to systemati

24 Here we develop a new method for total transcriptome profiling o

25 pon by the DeltacheY2-infected ticks did not develop a persistent infection in the murine host.

26 We develop a pore recognition approach to quantify similari

27 We develop a quantitative model that accounts for this effe

28 Schizosaccharomyces pombe Germinating spores develop a single germ tube that emerges from the outer s

29 Finally, we develop a statistical model that incorporates the uncert

30 olyacrylamide gel electrophoresis (PAGE), we develop a technique for fabrication of PAGE molecular si

31 Eighty-six patients (12.9%) developed a cancer during follow-up.

32 Based on these simulation tools, we have developed a first method to evaluate the parameters of t

33 ent with (177)Lu-DOTATATE: 8 patients (2.9%) developed a hematopoietic neoplasm (4 MDS, 1 AML, 1 MPN,

34 We now have developed a hypothesis regarding the mechanisms that lin

35 ution of the TL to intrinsic termination, we developed a kinetic assay that distinguishes effects of

36 We have developed a mathematical model to understand the signifi

37 rostatic pressure-induced edema in vitro, we developed a method of applied pressure to the basolatera

38 We have developed a method of polymerization control in which th

39 We further developed a method, iMAAPs, to infer multiple-wave admix

40 To fill this gap, we have developed a model to simulate the responses of all tacti

41 We developed a multiscale model of fibrinolysis that includ

42 We developed a new method (called REPPS) for incorporating

43 f neutrophils in LPS-induced endotoxemia, we developed a new mouse model, PMN(DTR) mice, in which inj

44 We developed a new multivariable linear model for GFR using

45 To investigate this claim, we developed a novel assay that allows for parallel profili

46 We developed a novel methodology for burden estimation and

47 We developed a panel of tunable expression platforms for th

48 We developed a platform for microfluidics-assisted cell scr

49 Here we developed a population-level microsatellite profiling ap

50 tients classified according to IA status and developed a predictive model based on genetic risk, esta

51 In this work, we have developed a protein-based model for the NiP center of ac

52 Here, we developed a sensitive and accurate multiplex miRNA profi

53 Here, we developed a sensitive sandwich enzyme-linked immunosorbe

54 We have developed a strategy to rewire the endogenous cellular r

55 Previously we developed a structure-based method for prediction of tra

56 To overcome this barrier, we developed a synthetic-biology approach based on a techni

57 39 in an in vivo cerebral ischemia model, we developed a transgenic mouse expressing human CD39 (hCD3

58 KEY MESSAGE: We have developed a unique male-sterility and fertility-restorat

59 tter subsidies to glacier-marine habitats by developing a multi-trophic level Bayesian three-isotope

60 licability of cotranscriptional SHAPE-Seq by developing a sequence-independent biotin-streptavidin (S

61 In addition to developing a simple method, this study articulates uniqu

62 possible, suggesting this is a first step in developing a simple way of controlling plastic flow in n

63 ataset represent an important foundation for developing a standardized test methodology for determina

64 on principle holds for all of these cases by developing a unifying mathematical framework that charac

65 d a novel mutant mouse (Dclre1c(leaky)) that develops a LS phenotype.

66 a mechanistic underpinning for the recently developed ablation procedure.

67 However, developing active, selective and stable electrocatalysts

68 ier identification of individuals at risk of developing AD and/or early stage AD for which current th

69 19 816 matched control subjects, 654 and 328 developed AF, respectively.

70 The risk of developing AF was 21.99 times higher (95% confidence int

71 There is great interest in developing alternative and sustainable strategies to ach

72 ated with RAI had an increased early risk of developing AML and CML but no other hematologic malignan

73 To develop an algorithm for accurate and early diagnosis of

74 There is an urgent need to develop an efficacious and affordable vaccine to control

75 The aim of this study was to develop an environmental-benign bio-measure that could b

76 We found that sapropels developed an analogous elemental milieu and harbored pro

77 We developed an evolutionary game theory model using Lotka-

78 No patient developed an orbital recurrence.

79 eness, thereby providing implications toward developing an effective therapy for TNBC.

80 ommensurability disappears, ferroelectricity develops, an additional commensurate magnetic structure

81 The aim of this study was to develop and characterize a specific small-molecule trace

82 We seek to develop and demonstrate a method for identifying those m

83 To develop and test a simulation-based operating room team

84 d-cloud point extraction (UA-CPE) method was developed and combined with flame atomic absorption spec

85 Based on this dataset, we developed and compared 2-class and 3-class DILI predicti

86 osable-syringe jet injectors, have also been developed and evaluated as alternatives to traditional B

87 o-beam refraction and one solenoid valve was developed and found to successfully generate digitized f

88 6 second-line new agents have been recently developed and offer new possibilities (pomalidomide, car

89 We developed and performed resistome analysis, an unbiased

90 study a simple colorimetric sensor should be developed and tested for the real-time detection of Cyt

91 INTERPRETATION: We developed and validated a novel clinical prediction mode

92 We developed and validated a rapid, sensitive, and robust m

93 he specialty of cancer survivorship has been developing and growing since the mid-1980s, but the term

94 mesenchymal and epithelial cell types in the developing and mature mouse ureter.

95 lls (MECs), and the vesicle transport system develops and matures.

96 Our strategy can be utilized to develop arrays of varying sizes and geometries, which ca

97 mpact of globalization on surgical care were developed as part of simultaneous data collection and an

98 The developed assay has the potential to be implemented in f

99 56.0% of patients developed at least 1 complication, and 26.9% experienced

100 protein binding are much more challenging to develop; attenuating the number of false positives and f

101 eported to increase the risk for children to develop autism spectrum disorder (ASD).

102 The package is developed based on a change-point based method with opti

103 nalysis of Cu, Fe, Mn and Zn in flaxseed was developed based on infrared-assisted acid digestion.

104 intact human embryos must not allow them to develop beyond 14 days or the appearance of the primitiv

105 Therefore, we developed biodegradable polymeric microspheres for the s

106 1 MPN, and 2 MDS/MPN) and 3 patients (1.1%) developed BM failure characterized by cytopenia and BM a

107 e effects in the intraparietal sulcus of the developing brain, those effects could be explained by pa

108 experience could cause lasting damage to the developing brain.

109 Cpt2M(-/-) mice developed cardiac hypertrophy and systolic dysfunction,

110 Children who developed caries in their primary dentition had a very d

111 oxygen exposure, preterm infants frequently develop chronic lung disease and have a significantly in

112 llow-up of 16.6 years, 31.7% of participants developed CKD.

113 However, only this newly developed CLIA test showed high specificity and correlat

114 mL, only one and three patients subsequently developed clinical and virological relapses.

115 ot well understood and often overlooked when developing clinically relevant bispecific therapeutics.

116 ing tip- and stalk-enriched gene sets in the developing collecting duct system.

117 vegetables was calculated by use of a newly developed comprehensive database.

118 y and biocompatible nano-dispersant has been developed comprising a multi-shelled nanoparticle termed

119 atients, it is crucial that nursing students develop confidence communicating with others to improve

120 and-tool overlap (HTO) not only in typically developed control participants but also in four of the f

121 We developed core shell lipid-polymer hybrid nanoparticles

122 infectious cause of newborn malformation in developed countries.

123 ed in national immunization programs in many developing countries.

124 cine to control canine-transmitted rabies in developing countries.

125 Here we developed covariates for multiphenotype studies (CMS), a

126 By engineering C-terminal charges, we develop CRY2high and CRY2low with elevated or suppressed

127 One patient developed decreased visual acuity secondary to radiation

128 c fibrosis (PI-CF) are at increased risk for developing diabetes.

129 Efforts are now underway to develop DOACs that inhibit components of the intrinsic a

130 s genetic risk alleles have a higher risk of developing DR.

131 Through an RNAi screen in the developing Drosophila eye, we found that partial APC/C i

132 The bright pink color developed due to ICT in the moderately stable cyano subs

133 ing antibodies (bnAbs) to HIV envelope (Env) develop during natural infection can help guide the rati

134 The least developed economies have been found to experience the hi

135 The results suggest a new framework for developing effective fusion inhibitory peptides.

136 There is a need to develop efficient statistical methods and computational

137 We previously developed eight gene association methods for genome-wide

138 In the developing embryo, melanoblasts originating from the neu

139 ems and may designate a unique direction for developing fast and efficient optoelectronic devices.

140 ction of tumor cells, mice lacking PITPalpha develop fewer lung metastases due to a reduction of fibr

141 efficient continuous flow protocol has been developed for bond C-H activation which promotes the alp

142 While rugged and robust assays may be easily developed for certain enzymes, HTS assays designed to id

143 Many tools have been developed for haplotype assembly-the reconstruction of i

144 ith alkyl/aryl groups on N and P), have been developed for heterolytic cleavage of H2 into a proton a

145 (18)F-T807 is a PET radiotracer developed for imaging tau protein aggregates, which are

146 In this work, a microfluidic device is developed for in-situ analysis of pesticide concentratio

147 mplified polymorphic DNA (RAPD) analysis was developed for its efficient and accurate detection in fo

148 could improve motor neural prostheses being developed for people with paralysis.

149 c, a meningococcal group A conjugate vaccine developed for the African meningitis belt, an enhanced m

150 oted by DABCO as a solid organobase has been developed for the rapid construction of a novel class of

151 and dynamic investigations, rationales were developed for the stabilizing effect at many of the muta

152 ria surveillance data provide opportunity to develop forecasting models.

153 ns of individuals are symptomatic (SYMP) and develop frequent bouts of recurrent disease.

154 One suggestion has been to develop genes encoding effector molecules that block par

155 icide DDT and its metabolites and obesity to develop hazard identification conclusions.

156 r architecture similar to that of the direct developing hemichordate Saccoglossus kowalevskii.

157 evaluated the incidence and time course for developing HF after pacemaker implantation for cAVB.

158 needed to identify patients at high risk of developing HF in the setting of right ventricular pacing

159 d that patients with irregular Z line do not develop HGD or esophageal cancer within 5 years after in

160 f sensors used here should be applicable for developing highly sensitive biosensors for various prote

161 Finally, DHHC7 KO mice developed hyperglycemia and glucose intolerance, thereby

162 The db/db mice developed hyperglycemia, oxidative stress, and nephropat

163 In the developing hypothalamus, the fat-derived hormone leptin

164 outs also had elevated thyroid manganese and developed hypothyroidism.

165 computational and structure-guided design to develop improved native-like trimers that reduce exposur

166 te stem cell fate provides opportunities for developing improved methods for tissue manufacture, acce

167 ac fecal occult blood test, interval cancers develop in 48% to 55% of the subjects.

168 aryngeal carcinoma (NPC), and lymphomas that develop in organ transplant recipients.

169 Before birth, B cells develop in the fetal liver (FL).

170 Cystic lesions of the transplant pancreas developed in 22 patients (1.8%): 12 pseudocysts, 2 cysts

171 t of renal GPCR-Gbetagamma inhibition in CKD developed in a clinically relevant murine model of nonis

172 METHOD: A self-designed questionnaire was developed in Arabic and used to interview people in diff

173 the 53 carotids with IPH at baseline, and it developed in five (7%) of the 40 carotids without IPH at

174 el activity-dependent technology called CANE developed in our laboratory, we identified and selective

175 PET was developed in the 1970s as an in vivo method to measure r

176 tigating brain glycosylation, which could be developed in to brain mapping applications, but also ser

177 ) patients died and 106 (41%) either died or developed indication for mitral valve surgery.

178 We therefore developed InFlo, a novel systems biology approach for ch

179 displayed ubiquitin variant (UbV) library to develop inhibitors targeting the DUBs USP7 and USP10, wh

180 50% of patients with RCDII, these Lin(-)IELs develop into a lymphoma for which no effective treatment

181 This approach can potentially be developed into a single-molecule toolbox to investigate

182 fh) cells, which provide help to B cells for developing into Ab-secreting cells, were similar between

183 Six patients (5%) developed invasive fungal infections and 5 patients (4%)

184 target population is a crucial milestone in developing IPV-Al.

185 pants with baseline CD4 count <350 cells/muL developed IRIS.

186 t the clinical context in which hyperkalemia develops is at least as important as the degree of hyper

187 renal stem/progenitor cell population in the developing kidney that in adult kidney contributes to ho

188 iss these position-specific short motifs, we developed kpLogo, a probability-based logo tool for inte

189 This work demonstrates a viable approach to develop lithium-sulfur batteries with practical energy d

190 r physiological shear stress, using recently developed live cell imaging and particle-tracking method

191 We have improved the original approach by developing long-read ChIA-PET, in which the length of th

192 The study offers design insights for developing low-cost surface microfluidic mixing devices

193 immunity by mediating V(D)J recombination in developing lymphocytes.

194 Our overall goal is to develop machine-learning approaches based on genomics an

195 e 255 patients with cysts >1.5 cm, 19 (7.5%) developed malignancy (P = .01).

196 All induced mice develop mammary tumours with 9qA1 (Yap1) and/or 6qA2 (Me

197 However, only Podo-GC-A KO mice developed massive albuminuria (controls: 35-fold; KO: 54

198 We have developed mathematic models of brain activity that allow

199 Here we develop mathematical models of Tfh cells in germinal cen

200 A recently developed metal-organic framework (MOF) catalyst for the

201 The applicability of the developed method for analysis of real samples was evalua

202 One recently developed method that utilizes this type of acceleration

203 Due to its generality, the developed methodology is applicable to a wide range of p

204 The developed methodology was then applied for E. coli quant

205 There is a need to develop methods that are robust to platform/batch effect

206 The crystals then continue to grow to develop morphologies characteristic of these additives.

207 Acute knockdown of Myt1l in the developing mouse brain mimicked a Notch gain-of-function

208 n that sarcopenia is a novel risk factor for developing NAFLD.

209 Developing nanotechnology that would allow molecular-lev

210 Excessive sedentary time is ubiquitous in developed nations and is associated with deleterious hea

211 Patients affected by C3 glomerulopathy can develop neovascular membranes as retinal complications o

212 None of the neonates developed nephrogenic systemic fibrosis.

213 hat express one CRTC3 allele (CRTC2/3m mice) develop neutrophilia and splenomegaly in adulthood due t

214 ragment-based lead discovery with efforts to develop new antimicrobials for mycobacterial infections.

215 ways we can leverage molecular data sets to develop new hypotheses for disease mechanisms, identify

216 nderstand how aging promotes CVD in order to develop new strategies to confront this challenge.

217 e mechanisms that result in LSC survival and develop new therapeutic approaches.

218 L5 signaling and illustrate the potential of developing new PAI-1- and CCL5-targeting therapy for pat

219 the serum half-life is an important issue in developing new therapeutic proteins and expanding applic

220 stablishes a key technology that intended to develop next generation point-of-care (POC) detection sy

221 We sought to develop Nicotiana benthamiana as a system to study NHR a

222 e cancer-related molecular mechanisms and to develop novel cancer therapies.

223 ell-defined microenvironments can be used to develop novel devices and methods in protein biophysics

224 In order to develop novel kappa agonists restricted to the periphery

225 We thus developed novel glycylation-specific antibodies with whi

226 n modulating the function of these cells and developing novel strategies for enhancing host defense t

227 Developing novel targets for SE therapy and diagnosis is

228 nvolved in HCMV replication is important for developing novel treatments.

229 Dscam is expressed along the developing optic pathway in a pattern consistent with a

230 Branching morphogenesis of developing organs requires coordinated but poorly unders

231 The recently developed peptide GL13K is used as an example to illustr

232 he prodrug, provides a compelling mandate to develop practical total syntheses of these agents.

233 gnitive outcomes associated with CTE and for developing preventive treatment programs.

234 an parainfluenza virus type 3 (rB/HPIV3) was developed previously as a vector expressing RSV fusion (

235 gammadelta-T-cell-deficient mice developed profound RPE and retinal damage at doses that

236 of patients with primary biliary cholangitis develop pruritus (itch) during the course of their disea

237 arboring wild-type Cyp24a1 (BVE(Cyp24a1-wt)) developed PTC at 5 weeks of age.

238 One approach is to develop radiosensitizing compounds.

239 on with redox reactions of iodine allows for developing rechargeable iodine-carbon batteries free fro

240 ities challenges policy makers' abilities to develop recommendations to effectively deploy registered

241 cally relevant genes for functional studies, developing reference variant-phenotype databases, adopti

242 ion and appreciation of immunodeficiency has developed, researchers have used vaccine responses as a

243 adioresistance in irradiated tumors can also develop, resulting in relapse.

244 Developing rice cultivars with higher [CO2] responsivene

245 tential of using a single receptor target to develop RNA aptamers with dual activity for effectively

246 with a more than 20-fold increased risk for developing schizophrenia.

247 es born before a gestational age of 32 weeks developed severe necrotising enterocolitis, of whom 222

248 ree patients with treated retinoblastoma who developed severe PVR and required enucleation.

249 Here, we develop skin grafts from mouse and human epidermal proge

250 r cells, the molecular effects of a recently developed small-molecule inhibitor of the KDM5 family of

251 approaches provided a better perspective for developing specific and sensitive devices with wide pote

252 We aim to increase insulin secretion by developing strategies that work through mechanisms indep

253 as potential targets provides a paradigm for developing strategies to treat respiratory distress in S

254 The Egyptian rousette develops subclinical productive infection with MARV but

255 of Treg therapy and technical challenges to developing successful cell therapy.

256 In an effort to develop synthetic materials that transduce mechanical fo

257 264 was designed and synthesized through the developed synthetic technologies and tested against drug

258 Here, we show that in developing T cells, the Bcl11b enhancer repositioned fro

259 person-years of follow-up, 5207 participants developed T2DM.

260 ildren with ASD and 65 age-matched typically developing (TD) children were compared by using lectin m

261 Hybrid classification models were developed that could predict solubility-enhancing mutati

262 e mild disease, dengue fever (DF), while few develop the life-threatening diseases dengue hemorrhagic

263 Additionally, we further developed the NTA methodology to explore its suitability

264 We have developed the simulation and the theoretical model toget

265 Upon completion of follow-up studies, we developed the working model that synaptic plasticity in

266 sts that it is a relatively easy property to develop through evolution.

267 The newly developed tight UF hollow fibers not only possess a smal

268 pathway activation, the signaling changes in developing tissues remain largely unknown.

269 ition reaction/Cope elimination sequence was developed to access novel 1,4,6,7-tetrahydro-5H-[1,2,3]t

270 he FutureDocs physician supply and need tool developed to anticipate future supply and need for all p

271 MISST is an iterative search process developed to be both agglomerative, to add sequences con

272 n and dichloromethane for lipid removal, was developed to detect and quantify as many metabolites as

273 sion levels of four host messenger RNAs, was developed to discriminate critically ill adults with inf

274 A dichotomous method was also developed to enable rapid detection and avoid tedious ca

275 A mechanical model is developed to explain the interaction of the three compon

276 A physiologic method was developed to further advance central BP measurement.

277 The mode expansion theory is developed to help understand how the gradient metasurfac

278 ion at these entry ports, vaccines are being developed to induce pathogen-specific SIgA in addition t

279 A scalable procedure was developed to install the C-3 amido group.

280 Although there are numerous devices developed to isolate individual circulating tumor cells

281 A methodology has been developed to measure nanoparticle mass and density, by c

282 ion, lipofection or microinjection have been developed to overcome the cellular plasma membrane, but

283 Computational methods have been developed to predict the genomic locations of active enh

284 A novel measurement system was developed to quantify methane leaks and losses.

285 A biochemical complementation assay was developed to show that a unique, conserved domain at the

286 This protocol is based on a method developed to study yeast vacuolar fusion.

287 fied predictors of final macular status, and developed two predictive models.

288 ox4 are associated with an increased risk of developing type 2 diabetes.

289 normal motor function (hypokinesia), but can develop uncontrollable movements known as dyskinesia upo

290 Not all women infected with chlamydiae develop upper genital tract disease, but the reason(s) f

291 ng peptide electrophoretic mobility has been developed using large-scale bottom-up proteomic CE-MS da

292 is of this virus; with the intent to rapidly develop vaccines and therapeutics.

293 of neuronal progenitor cells, damage to the developing vascular system of the brain, and altered cel

294 st that alternative splicing of C-Src in the developing vertebrate nervous system evolved to regulate

295 ss-coupling of naphthylamines with azoles is developed via C-H functionalization and C-N bond formati

296 Cavitary optic disc maculopathy develops when fluctuating pressure gradients along anoma

297 Stereochemical models developed with the aid of density functional theory calc

298 We developed Yet Another RNA Normalization software pipelin

299 We also track migrating cells in the developing zebrafish embryo, demonstrating the utility o

300 n of craniofacial cartilage and the heart in developing zebrafish.