ライフサイエンスコーパス: developing

1 cal samples were collected from 89 typically developing 1-year-olds.

2 By developing a carbonaceous emissions database for the Uni

3 imaging agent DOTATOC as the foundation for developing a dual-labeled analog.

4 Developing a greater understanding of personal and envir

5 is who are at increased risk of subsequently developing a hematopoietic malignancy, suggesting that t

6 This paper focuses on developing a label-free electrochemical biosensor with h

7 this work provides an important insight for developing a molecular dynamic continuum for potential c

8 tter subsidies to glacier-marine habitats by developing a multi-trophic level Bayesian three-isotope

9 ssionals' perspectives is one of the keys to developing a multi-use intervention.

10 is to bridge the science-policy interface by developing a natural capital accounting structure for so

11 ared with ConvRT (31% vs 51%; P = .01) while developing a new neuroendocrine axis dysfunction in pati

12 such motor-filament materials is critical to developing a physical model of the cytoskeleton and desi

13 Upon developing a Rab8a activation assay, we show that TLR3 a

14 licability of cotranscriptional SHAPE-Seq by developing a sequence-independent biotin-streptavidin (S

15 In addition to developing a simple method, this study articulates uniqu

16 possible, suggesting this is a first step in developing a simple way of controlling plastic flow in n

17 ataset represent an important foundation for developing a standardized test methodology for determina

18 research on understanding virus biology and developing a suite of strategies for disease interventio

19 We addressed this problem by developing a TCR-transgenic (Tg) mouse with CD4 T cells

20 on principle holds for all of these cases by developing a unifying mathematical framework that charac

21 his review discusses recent progress made in developing a vaccine and novel treatments for human immu

22 iew of the current progress underway towards developing a vaccine to prevent cryptococcosis.

23 Future research should focus on developing a working definition of familial PCA for clin

24 w that this strategy is a first step towards developing "activator drugs" for a large number of genet

25 However, developing active, selective and stable electrocatalysts

26 ier identification of individuals at risk of developing AD and/or early stage AD for which current th

27 TREM2, strongly impact the lifetime risk of developing AD.

28 The risk of developing AF was 21.99 times higher (95% confidence int

29 but it will also increase the probability of developing age-related diseases such as Alzheimer's dise

30 SIV infection protected rhesus macaques from developing AIDS and partially from vaginal SIV acquisiti

31 There is great interest in developing alternative and sustainable strategies to ach

32 Identifying individuals at risk for developing Alzheimer disease (AD) is of utmost importanc

33 ated with RAI had an increased early risk of developing AML and CML but no other hematologic malignan

34 lude efforts to safeguard hundreds of direct-developing amphibian species globally.

35 Here, we address this issue by developing an algorithm that estimates dd-cfDNA levels i

36 We sought to extend BMI lifetime by developing an algorithmic technique, implemented entirel

37 eness, thereby providing implications toward developing an effective therapy for TNBC.

38 rch needs in clarifying reaction mechanisms, developing analytical methods for both liquid and gas ph

39 In the interest of developing and characterizing a polymeric nanoparticle p

40 These studies have provided a foundation for developing and evaluating DENV4 vaccines.

41 he specialty of cancer survivorship has been developing and growing since the mid-1980s, but the term

42 mesenchymal and epithelial cell types in the developing and mature mouse ureter.

43 homolog, ShcD, is robustly expressed in the developing and mature nervous system, but its contributi

44 cal signaling in the extracellular matrix of developing and regenerating tissues.

45 how periodic patterns could self-organize in developing animals.

46 Developing, applying, and improving the means of evaluat

47 gene expression and protein localization in developing Arabidopsis plants and Nicotiana benthamiana

48 xpression along the dorsoventral axis of the developing arches.

49 ngles in the brain are highly susceptible to developing arthritis.

50 w familial Risk (HR or LR, respectively) for developing Autism Spectrum Disorders (ASD).

51 These developing axonemes were positioned to coordinate traffi

52 ng furthering our understanding of bacteria, developing better susceptibility testing tools, and over

53 lebbing, with only 20% of the silenced cells developing blebs compared with 53% of the control cells.

54 Resident cell populations of the developing brain have been suggested to be more suscepti

55 crodomains, defined by engrailed 1 (En1) and developing brain homeobox 1 (Dbx1).

56 e effects in the intraparietal sulcus of the developing brain, those effects could be explained by pa

57 experience could cause lasting damage to the developing brain.

58 ation is a major component of disease in the developing brain.

59 hibit the growth, or stimulate the death, of developing cancer cells.

60 The observed rate of developing cancer in the group that was stable at the 5-

61 rstanding important biological processes and developing carbohydrate-based pharmaceutics.

62 ns due to impaired neuronal migration in the developing cerebral cortex.

63 e original community sample of 338 typically developing children, participants were 186 socioeconomic

64 African Americans have a heightened risk of developing chronic and end-stage kidney disease, an asso

65 ss, but this comes with an increased risk of developing chronic kidney disease.

66 all-oral therapy had a 30% decreased risk of developing CKD (HR, 0.70; 95% CI, 0.55-0.88).

67 ards models were used to compare the risk of developing CKD in HCV patients compared with non-HCV pat

68 ot well understood and often overlooked when developing clinically relevant bispecific therapeutics.

69 ABSTRACT: There is a need for developing clinically translatable therapy for preventin

70 ever, there has been only limited success in developing cold-hardy cultivars.

71 phatic vascular network, including the later-developing collateral cardinal, spinal, superficial late

72 ing tip- and stalk-enriched gene sets in the developing collecting duct system.

73 Rs) and 95% confidence intervals (95%CI) for developing colorectal cancer (2,636 incident cases) were

74 electricity creates significant benefits for developing communities.

75 Therefore, there is a great demand in developing computational methods to identify chromatin a

76 ged 7-17 years with DSM-IV OCD and typically developing controls underwent 3 T proton echo-planar spe

77 lly valid at identifying patients at risk of developing COPD.

78 stics can identify those at highest risk for developing corneal perforation and/or needing TPK.

79 characteristics that predict a high risk of developing corneal perforation and/or the need to underg

80 gnal transducers SMAD1/5/8 were activated in developing coronary arteries.

81 t of storage oil and protein biosynthesis in developing COS.

82 eutralization by antibodies, are crucial for developing cost-effective and yet rigorous and reproduci

83 of primary emissions from cookstoves used in developing countries may make important contributions to

84 omas (HCCs) is dominated by its incidence in developing countries, accounting for >700,000 estimated

85 In many developing countries, increased use of fertilizers is a

86 Increased efforts are needed, especially in developing countries, to ensure access to safe abortion.

87 olium (the pork tapeworm) is present in most developing countries, where it is a frequent cause of se

88 ed in national immunization programs in many developing countries.

89 main sources of calories and protein in many developing countries.

90 l for fighting vitamin A deficiency (VAD) in developing countries.

91 cine to control canine-transmitted rabies in developing countries.

92 ving accessibility to medical diagnostics in developing countries.

93 In the 9 developing country sites, nasopharyngeal/oropharyngeal s

94 In a developing-country context, the International Monetary F

95 h and highlight different approaches towards developing crops with enhanced PUE.

96 ghout life, culminating in increased risk of developing CVD.

97 These results offer a promising path for developing DC subset-specific immunotherapies that canno

98 eath-censored graft loss and mortality after developing dementia or the AD subtype of dementia, separ

99 evelop postoperative delirium are at risk of developing dementia within 5 years after cardiac surgery

100 bust findings have been obtained in patients developing depression in the context of treatment with i

101 narrowband and providing the possibility of developing devices with unprecedentedly high time-bandwi

102 it function increases the susceptibility for developing diabetes in a sex-dependent manner.

103 rapy does not appear to increase the risk of developing diabetes mellitus in NET patients, whereas di

104 c fibrosis (PI-CF) are at increased risk for developing diabetes.

105 ve incomplete penetrance, with some patients developing disease in their twenties and a small portion

106 of ASB and SSB consumption with the risk of developing DM and the potential benefit of replacing SSB

107 s genetic risk alleles have a higher risk of developing DR.

108 Through an RNAi screen in the developing Drosophila eye, we found that partial APC/C i

109 Developing drought-resistance varieties is a major goal

110 mation, TcpB might be a candidate target for developing drugs against LPS-induced septicemia.

111 hange is very advantageous to biologists for developing early disease diagnosis biomarkers.

112 r-level events in the Tropics, impairing the developing economies of equatorial coastal cities and th

113 The results suggest a new framework for developing effective fusion inhibitory peptides.

114 cells in vivo is crucial to identifying and developing effective latency-reversing therapies.

115 red in the present research is essential for developing effective remediation strategies that are con

116 n of cardiovascular disease is important for developing effective strategies to improve outcomes.

117 These results may pave the path toward developing electronically controllable wound dressings t

118 labels nerve fascicles in the tongue of the developing embryo and demonstrates a similar stereotyped

119 However its downstream network in the developing embryo is not fully characterized.

120 In the developing embryo, melanoblasts originating from the neu

121 neuronal maturation and OR expression in the developing embryonic OE.

122 ethality potentially due to iron overload in developing embryos.

123 d differentiation of progenitor cells in the developing enteric nervous system are controlled by mole

124 iological mechanisms may explain the risk of developing epilepsy following incident depression.

125 V genotype 1 tended to have a higher risk of developing ESRD (HR, 3.60 95% CI 1.83-7.07) compared wit

126 yonic tissue, and observed expression in the developing eye, neural tube, brain and kidney.

127 ems and may designate a unique direction for developing fast and efficient optoelectronic devices.

128 Here, diffusion anisotropy within the developing fetal cerebral cortex is longitudinally chara

129 rine, and male reproductive systems, and the developing fetus and neonate.

130 ome in adults and congenital microcephaly in developing fetuses and infants.

131 l fluids has been in part a driving force in developing future diagnostic and therapeutic strategies.

132 Interest in developing gene drive systems to control invasive specie

133 The risk of developing glaucoma increases with age; therefore, under

134 h clonal haemopoiesis have increased risk of developing haematological malignancies.

135 Specifically, the risk of developing heart failure is higher in patients with diab

136 r architecture similar to that of the direct developing hemichordate Saccoglossus kowalevskii.

137 evaluated the incidence and time course for developing HF after pacemaker implantation for cAVB.

138 needed to identify patients at high risk of developing HF in the setting of right ventricular pacing

139 Developing high-capacity anodes is a must to improve the

140 liver, and adipose tissues were resistant to developing high-fat diet-induced obesity and had signifi

141 ssities can be an important route to further developing higher performance devices.

142 This work will enable future efforts in developing highly efficient biomimetic assays for intera

143 f sensors used here should be applicable for developing highly sensitive biosensors for various prote

144 ion of young GABAergic interneurons into the developing hippocampus is slowed in Pafah1b1(+/-) mice.

145 Using the acini-ductal network of the developing human and murine salivary gland, we demonstra

146 Electroencephalographic recordings from the developing human brain are characterized by spontaneous

147 s (ZIKV) can cause substantial damage to the developing human brain.

148 an-PSC-derived neural crest cells (NCCs) and developing human intestinal organoids (HIOs).

149 f radial glia maturation and neurogenesis in developing human telencephalon.

150 In the developing hypothalamus, the fat-derived hormone leptin

151 tivity were all significant risk factors for developing IA and were combined in a predictive model.

152 cificity of 70.4%/89.2% and a probability of developing IA of 56.7%.

153 to their children could affect their risk of developing IBD.

154 h severe enteritis-are at increased risk for developing IBS, as are individuals with psychological di

155 It can also take advantage of the developing immune system and the not-yet-stabilized gut

156 ion can be detrimental or beneficial, before developing immunomodulatory therapies, it is necessary t

157 te stem cell fate provides opportunities for developing improved methods for tissue manufacture, acce

158 Developing in vitro models of HIV-1 latency that recapit

159 hway activity, and validated our approach of developing individualized treatments in mice with PDX tu

160 in early development in 71 healthy typically developing infants, either at High or Low familial Risk

161 Developing integrative computational methods to analyze

162 ular (CV) risk in PTSD will pave the way for developing interventions to improve sympathetic function

163 fh) cells, which provide help to B cells for developing into Ab-secreting cells, were similar between

164 imatinib treatment prevents progenitors from developing into mast cells in vitro.

165 target population is a crucial milestone in developing IPV-Al.

166 renal stem/progenitor cell population in the developing kidney that in adult kidney contributes to ho

167 erstanding lignin biosynthesis mechanism and developing lignin based chemicals or materials under the

168 genome-wide predictions of enhancers in the developing limb, available through a user-friendly onlin

169 rogenitor cells from transmigrating into the developing liver, and Gata4-mutant embryos died from sub

170 We have improved the original approach by developing long-read ChIA-PET, in which the length of th

171 The study offers design insights for developing low-cost surface microfluidic mixing devices

172 e cells recapitulated epithelial-mesenchymal developing lung interactions.

173 immunity by mediating V(D)J recombination in developing lymphocytes.

174 s and as such provide a useful framework for developing machine-learning algorithms for modular and h

175 itional TSTRs to regulate gene expression in developing male gametes and histone retention in mature

176 ceral adiposity confers significant risk for developing metabolic disease in obesity whereas preferen

177 , but its relevance to the long-term risk of developing metabolic disorders is unknown.

178 indicate standard of care and importance of developing methods of treatments.

179 though significant progress has been made in developing microfluidic systems for nucleic acid and who

180 ed spontaneous transient outward currents in developing MNTB neurons.

181 ystal growth in detail have so far relied on developing models that are usually applicable to only on

182 sturbs sleep and might increase the risk for developing mood disorders.

183 Acute knockdown of Myt1l in the developing mouse brain mimicked a Notch gain-of-function

184 fic function and sumoylation of FOXP2 in the developing mouse cerebellum.

185 Despite remarkable progress in developing multifunctional materials, spin-driven ferroe

186 hereafter CTIP1) is highly expressed in the developing murine epidermis.

187 n that sarcopenia is a novel risk factor for developing NAFLD.

188 Developing nanotechnology that would allow molecular-lev

189 pectedly, in vivo examination of early-stage developing nephron tubules reveals that cell division is

190 r, these studies provide novel insights into developing networks that underlie memory, the mechanisms

191 or mechanistic analysis of the plasticity of developing neural circuits by showing that sensory exper

192 gulators modulated by diabetes in the murine developing neuroepithelium.

193 individuals who are at an increased risk of developing neurological cognitive comorbidities, and may

194 glia undergo morphological changes, while in developing neurons and oligodendrocyte progenitor cells

195 tion of precise synaptic connections between developing neurons is critical to the formation of funct

196 ed single-cell RNA-sequencing (scRNA-seq) of developing neurons to dissect/identify NPC subtypes and

197 es in neuronal excitability, particularly in developing neurons, may contribute to ASD etiology.

198 Developing new analytical tools to detect these patterns

199 ion, it may represent a potential target for developing new antifungals.

200 on in response to environmental change while developing new hypotheses concerning adaptation to urban

201 Cumulative incidence of developing new neuroendocrine dysfunction at 5 years was

202 L5 signaling and illustrate the potential of developing new PAI-1- and CCL5-targeting therapy for pat

203 thetics research in amputee patients aims at developing new prostheses that move and feel like real l

204 a major focus of the oil industry is toward developing new technologies to increase recovery.

205 the serum half-life is an important issue in developing new therapeutic proteins and expanding applic

206 isease progression presents a challenge when developing new therapies for patients.

207 improving existing treatments such as CPT or developing new treatments is needed.

208 ear, compared to 0.19+/-0.12 mm/year in eyes developing new-onset GA (5/21).

209 ignal-mediated mechanism holds potential for developing novel approaches to regenerating pancreatic b

210 n modulating the function of these cells and developing novel strategies for enhancing host defense t

211 Developing novel targets for SE therapy and diagnosis is

212 Research in this area requires developing novel techniques for single-cell transcriptio

213 ogical processes and has a crucial impact in developing novel therapeutic strategies.

214 assemble without apparent toxicity may help developing novel therapies for amyloid diseases.

215 nvolved in HCMV replication is important for developing novel treatments.

216 In developing nutrition-sensitive agriculture, the nutritio

217 Hazard ratios (HRs) for developing OAG with 95% CIs.

218 t cohort entry were at 51% increased risk of developing obesity during childhood and adolescence comp

219 pful in screening children with high risk of developing obesity.

220 regnancy may be associated with harm for the developing offspring.

221 al transcriptional profiles in the adult and developing olfactory system of the six species suggest t

222 t first control, with homeostatic mechanisms developing only later.

223 Dscam is expressed along the developing optic pathway in a pattern consistent with a

224 Branching morphogenesis of developing organs requires coordinated but poorly unders

225 As "ground truth" for developing our method, we used Richmond Agitation Sedati

226 ly formed but are lost during meiosis in the developing ovary, leading to adult female sterility.

227 increased by 2 degrees C in response to the developing Pacific El Nino.

228 and Sema3e, is ectopically activated in the developing palatal mesenchyme in Osr2(-/-) embryos.

229 us target of canonical Wnt signaling, in the developing palatal mesenchyme, particularly in the poste

230 RRK2) are associated with increased risk for developing Parkinson's disease (PD).

231 tion provides a comprehensive foundation for developing PCC/PGL precision medicine.

232 HIV should be shared to support progress in developing pediatric formulations for other diseases, in

233 tool to screen for patients at high risk of developing persistent pain after breast cancer surgery.

234 for interrogating cell regulation events and developing pharmacological strategies for modulating cel

235 se transition opens up new possibilities for developing phase-change devices based on atomically thin

236 Whether developing postsynaptic neurons establish connections wi

237 tify prognostic subgroups among 106 patients developing posttransplant recurrence from 1984 to 2014,

238 high-capacity but expensive CO2 sorbent for developing practical or cost-effective CO2 technologies.

239 gnitive outcomes associated with CTE and for developing preventive treatment programs.

240 To determine the time and risk factors for developing proliferative diabetic retinopathy (PDR) and

241 s and deposition, which occurred only in the developing protuberance.

242 ystal microcavities, both of which have been developing rapidly over the past few years.

243 on with redox reactions of iodine allows for developing rechargeable iodine-carbon batteries free fro

244 cally relevant genes for functional studies, developing reference variant-phenotype databases, adopti

245 ains a leading cause of death in children in developing regions, killing 114,900 globally in 2014.

246 s, mainly in developed countries but also in developing regions.

247 APOL1 mutant alleles are at elevated risk of developing renal diseases.

248 re do not appear to be at increased risk for developing renal toxicity due to administration of intra

249 Developing research in infectious and tropical diseases

250 Developing rice cultivars with higher [CO2] responsivene

251 plications for increasing biomass yields and developing robust solar energy devices.

252 ootward polar localization, respectively, in developing root protophloem cells.

253 sia was associated with an increased risk of developing ROP among an unrestricted cohort but with a r

254 evelopmental delays in childhood and risk of developing schizophrenia and autism.

255 with a more than 20-fold increased risk for developing schizophrenia.

256 For example, mice lacking TSC2 in developing SCs displayed hyperproliferation of undiffere

257 transcriptome of C. avigera var pulcherrima developing seeds.

258 N1 is expressed mainly in floral tissues and developing seeds.

259 cidate fundamental structural aspects of the developing sensory systems in Drosophila.

260 Here we addressed these issues by developing single-cell multiple displacement amplificati

261 By comparison with strain maps of the developing skeleton, we identify canonical Wnt signallin

262 ot ignore Bd as a potential threat to direct developing species simply because they are less exposed

263 approaches provided a better perspective for developing specific and sensitive devices with wide pote

264 nical course of AMD and increase the risk of developing specific sub-phenotypes.

265 eptors assemble in the inner membrane of the developing spore.

266 Here, we present a pipeline for developing STR markers directly from high-throughput sho

267 We aim to increase insulin secretion by developing strategies that work through mechanisms indep

268 as potential targets provides a paradigm for developing strategies to treat respiratory distress in S

269 of Treg therapy and technical challenges to developing successful cell therapy.

270 Developing surface-enhanced Raman spectroscopy (SERS) ba

271 iers surviving to their ninth decade without developing symptoms.

272 In addition, we suggest developing synthetic vesicles as a new delivery vehicle

273 Here, we show that in developing T cells, the Bcl11b enhancer repositioned fro

274 the use of Crybodies as a powerful tool for developing tailor-made insecticides against new target i

275 The data provide rationale for developing TCRm antibodies as therapeutic agents for can

276 ildren with ASD and 65 age-matched typically developing (TD) children were compared by using lectin m

277 DHD and thirty age- and IQ-matched typically developing (TD) controls underwent resting-state functio

278 for exploring condensed matter phenomena and developing technological applications.

279 ry street in a 30-km(2) area of Oakland, CA, developing the largest urban air quality data set of its

280 y oligodendrocytes is therefore critical for developing therapies for the treatment of MS.

281 f1 short isoforms are adequate in supporting developing thymocytes to traverse through maturation ste

282 pathway activation, the signaling changes in developing tissues remain largely unknown.

283 ments has been challenging in the context of developing tissues where material is limited and cell ty

284 traumatized individuals who are at risk for developing trauma-related disorders.

285 h their mtDNA payload are transferred in the developing tumour, and provide functional evidence for a

286 ox4 are associated with an increased risk of developing type 2 diabetes.

287 of neuronal progenitor cells, damage to the developing vascular system of the brain, and altered cel

288 in other species show enriched expression in developing vasculature.

289 st that alternative splicing of C-Src in the developing vertebrate nervous system evolved to regulate

290 These findings are consistent with the developing view that the LHb promotes a negative reward

291 compromised hosts are at particular risk for developing virus-related pathology; thus, the impact of

292 5 results and to estimate the probability of developing vision-related disability during follow-up.

293 nterocular decorrelation of input signals in developing visual cortex can cause impaired binocular vi

294 rsistent impact of MD on synapse loss in the developing visual cortex.

295 The risk of developing weak grip strength (assessed as a binary yes

296 period of forced starvation while they brood developing young inside their mouths.

297 n of hindbrain segments (rhombomeres) in the developing zebrafish as an example, but the mechanisms i

298 Intriguingly, developing zebrafish come to control the initiation of l

299 We also track migrating cells in the developing zebrafish embryo, demonstrating the utility o

300 n of craniofacial cartilage and the heart in developing zebrafish.