ライフサイエンスコーパス: diacetyl

1 likely to encode a receptor for the odorant diacetyl.

2 ely maintained the chemotaxis ability toward diacetyl.

3 cetaldehyde, glycidol, acrolein, acetol, and diacetyl.

4 s aromatized with (-)-alpha-pinene than with diacetyl.

5 hyl-2-propene to provide 5-exomethylene-1, 3-diacetyl-1,3-diazacyclohexane 28.

6 formaldehyde with acetylacetone to form 3,5-diacetyl-1,4-dihydrolutidine (DDL), we measured reflecta

7 in vitro the cleavage of the Pth substrates diacetyl-[14C]lysyl-tRNA and acetyl-[14C]phenylalanyl-tR

8 sure to the alpha-diketone butter flavoring, diacetyl (2,3-butanedione).

9 Flavoring chemicals in e-cigarettes: diacetyl, 2,3-pentanedione, and acetoin in a sample of 5

10 was captured and analyzed for total mass of diacetyl, 2,3-pentanedione, and acetoin, according to OS

11 pentanedione (112, 241, 318, or 354 ppm), or diacetyl (240 ppm) for 6 hours were sacrificed the follo

12 ate 7-acetyl-4-deacetylbaccatin III and 7,13-diacetyl-4-deacetylbaccatin III substrates at C4, sugges

13 accatin III, 7-acetyl-, 13-acetyl-, and 7,13-diacetyl-4-deacetylbaccatin III.

14 hin films of vapor-deposited heptakis (2,3-O-diacetyl-6-O-tertbutyl-dimethylsilyl)-beta-cyclodextrin

15 xtrin family, the sodium salt of octakis(2,3-diacetyl-6-sulfato)-gamma-cyclodextrin (ODAS-gamma CD) h

16 f phosphate to the plants and is mediated by diacetyl, a bacterial volatile compound.

17 Diacetyl, a known respiratory hazard, along with acetoin

18 f the major flavour compounds (acetaldehyde, diacetyl, acetoin, and 2-butanone) followed a sigmoidal

19 oic and 5-oxopyrrolidine-2-carboxylic acids, diacetyl, acetoin, and an unidentified volatile.

20 Therefore, diacetyl affects the type of relation between plant host

21 flow photochemical addition of propellane to diacetyl allowed construction of the bicyclo[1.1.1]penta

22 the retention and release characteristics of diacetyl and (-)-alpha-pinene in oil-in-water (o/w) emul

23 iogenesis was significantly downregulated by diacetyl and 2,3-pentanedione in NHBE cells.

24 epithelial (NHBE) cells that were exposed to diacetyl and 2,3-pentanedione, respectively.

25 f common genes (142 genes) perturbed by both diacetyl and 2,3-pentanedione.

26 ccus cremoris also played a role by limiting diacetyl and acetoin formation, which otherwise results

27 ic re-routing of citrate by L. cremoris from diacetyl and acetoin towards alpha-ketoglutarate.

28 Because of the associations between diacetyl and bronchiolitis obliterans and other severe r

29 revealed that only 2,3-butanediol, acetoin, diacetyl and formate vary with the increase of pressure

30 Diacetyl and its chemical cousin 2,3-pentanedione are co

31 e, propanoic acid and 4-ethylphenol for JRE, diacetyl and methional/furfural for JPX, acetoin for MRE

32 ed NADPH-dependent reductase activity toward diacetyl and methylglyoxal, toxic electrophilic dicarbon

33 ncreased bacterial survival upon exposure to diacetyl and methylglyoxal.

34 Glycosylation of the 4-OH groups of the N,N-diacetyl and N-acetyl-N-benzyl glucosamine was also foun

35 est amount of butterscotch aromatic compound diacetyl and polyhydroxyalkyl pyrazines (fructosazine an

36 In vitro experiments demonstrated that diacetyl and structurally related volatiles inhibited co

37 quartile of estimated cumulative exposure to diacetyl and the frequency and extent of airway obstruct

38 tivities predominantly target H4 to give the diacetyl and triacetyl species; some acetylation of H2A

39 aimed to determine if the flavoring chemical diacetyl and two other high-priority flavoring chemicals

40 tent carboxonium-pyrenium dications, whereas diacetyl- and dibenzoylpyrenes are diprotonated to give

41 elevation in intracellular Ca2+ levels after diacetyl application.

42 phosphoric acid catalyst in conjunction with diacetyl as a combined hydrogen atom transfer reagent an

43 furaneol was incubated with methylglyoxal or diacetyl at elevated temperatures and the resulting reac

44 eveloped the first fluorescence-based assay, diacetyl benzene (DAB)-APT, for the measurement of APT a

45 This new assay uses 1,2-diacetyl benzene/beta-mercaptoethanol, which forms a flu

46 ibitor, MeU-diNAG (4-methylumbelliferyl-N,N'-diacetyl-beta-D-chitobioside).

47 Copper(II)-diacetyl-bis(4-methylthiosemicarbazonato) (Cu-ATSM) is a

48 at oral treatment with the therapeutic agent diacetyl-bis(4-methylthiosemicarbazonato)copper(II) [Cu(

49 The hypoxia PET tracer (64)Cu-diacetyl-bis(N(4)-methylthiosemicarbazonate) ((64)Cu-ATS

50 (64)Cu-diacetyl-bis(N(4)-methylthiosemicarbazonate), (64)Cu-ATS

51 oxia demonstrated by PET with (60)Cu-labeled diacetyl-bis(N(4)-methylthiosemicarbazone) ((60)Cu-ATSM)

52 orothymidine ((18)F-FLT), and (61)Cu-labeled diacetyl-bis(N(4)-methylthiosemicarbazone) ((61)Cu-ATSM)

53 mpounds, 2-deoxyglucose (2-DG) and copper(II)diacetyl-bis(N(4)-methylthiosemicarbazone) ((64)Cu-ATSM)

54 c administration of hypoxia-selective (64)Cu-diacetyl-bis(N(4)-methylthiosemicarbazone) ((64)Cu-ATSM)

55 Copper(II)-diacetyl-bis(N(4)-methylthiosemicarbazone) (copper-ATSM)

56 Tumor uptake of copper(II)-diacetyl-bis(N(4)-methylthiosemicarbazone) (copper-ATSM)

57 Cu-Diacetyl-bis(N(4)-methylthiosemicarbazone) (Cu-ATSM) is

58 We showed previously that, in vitro, copper-diacetyl-bis(N(4)-methylthiosemicarbazone) (Cu-ATSM) upt

59 Copper-64-Diacetyl-bis(N(4)-methylthiosemicarbazone) [(64)Cu][Cu(A

60 within tumors, such as (60/62/64)Cu-labeled diacetyl-bis(N(4)-methylthiosemicarbazone) and (18)F-flu

61 Herein we demonstrate that copper(II)-diacetyl-bis(N(4)-methylthiosemicarbazone)(CuATSM), clin

62 bis(N-4-methyl-3-thiosemicarbazone) and zinc diacetyl-bis(N-4-methyl-3-thiosemicarbazide) display the

63 Diacetyl-bis(N-4-methyl-3-thiosemicarbazone) and zinc di

64 zomycin arabinoside [(18)F-FAZA], and (64)Cu-diacetyl-bis(N4-methylsemicarbazone) [(64)Cu-ATSM]) in a

65 DR1 expression on the accumulation of (64)Cu-diacetyl-bis(N4-methylthiosemicarbazone) ((64)Cu-ATSM) a

66 The PET tracer copper(II)-diacetyl-bis(N4-methylthiosemicarbazone) ((64)Cu-ATSM) h

67 in-arabinofuranoside ((18)F-FAZA) and (64)Cu-diacetyl-bis(N4-methylthiosemicarbazone) ((64)Cu-ATSM) h

68 We have evaluated Cu-diacetyl-bis(N4-methylthiosemicarbazone) (Cu-ATSM), an e

69 ous promoter directs behavioral responses to diacetyl, but not to another odorant detected by the AWA

70 Chemotaxis toward one such odorant, diacetyl (butanedione), requires the function of a seven

71 rologous system and show that it responds to diacetyl by activation of a G protein signaling pathway.

72 cited aliphatic ketones, such as acetone and diacetyl, can be used as promising low-cost radical init

73 The reactive alpha-dicarbonyl group in diacetyl causes protein damage in vitro.

74 r serpentine receptors related to the ODR-10 diacetyl chemoreceptor is very large, with at least 197

75 The disaccharide N,N'-diacetyl-chitobiose, (GlcNAc)2, is critical in chitin di

76 g the reducing-end alpha and beta anomers of diacetyl-chitobiose, which is a disaccharide that forms

77 This unexpected susceptibility to diacetyl chloramphenicol was wholly or partly the conseq

78 chaeta aurantia was nearly as susceptible to diacetyl chloramphenicol, the product of chloramphenicol

79 of the presence of either chloramphenicol or diacetyl chloramphenicol.

80 he treatment with lees for ethyl propionate, diacetyl, cis-3-hexenol, acetic acid, benzyl alcohol, an

81 served in human cells is consistent with the diacetyl concentration ranges that allow efficient nemat

82 ethyl-2-furfural, glyoxal, methylglyoxal and diacetyl concentrations were determined to form a multir

83 ultaneous binding and recognition of diverse diacetyl-containing peptides by BRD4.

84 Diacetyl crosses the blood-brain barrier and exposure ca

85 Ab initio asymmetric syntheses of methyl N,O-diacetyl-D-3-epi-daunosaminide and methyl N,O-diacetyl-D

86 ysis, and acetate protection gave methyl N,O-diacetyl-D-3-epi-daunosaminide and methyl N,O-diacetyl-D

87 iacetyl-D-3-epi-daunosaminide and methyl N,O-diacetyl-D-ristosaminide, employing diastereoselective e

88 iacetyl-D-3-epi-daunosaminide and methyl N,O-diacetyl-D-ristosaminide.

89 Glyoxal (GO), methylglyoxal (MGO), diacetyl (DA) and 3-deoxyglucosone (3-DG) were found in

90 Diacetyl (DA; 2,3-butanedione) is a highly reactive alph

91 Diacetyl decreased proglucagon mRNA and total GLP-1 from

92 9,10-Dimethoxyphenanthrene gives its 3,6-diacetyl derivative in good yield and in large amounts.

93 The ligands were synthesized from the diacetyl derivative of the central linker by a Friedland

94 The precursor diacetyl derivatives were, in turn, prepared by pathways

95 The rapid and robust diacetyl derivatization at low temperatures (e.g., -20 d

96 Critically, diacetyl derivatization enables the differentiation of d

97 ize acyl migration, a facile low temperature diacetyl derivatization to stabilize regiospecificity, a

98 -butanol varied notably with roasting, while diacetyl emerged as a roasting degree marker.

99 Under phosphate-deficient conditions, diacetyl enhances phytohormone-mediated immunity and con

100 Diacetyl exposure halted proliferation of a neuroblastom

101 roarylbenzaldehydes with aromatic amines and diacetyl, followed by double intramolecular oxidative ar

102 eaction-based, targetable probe based on the diacetyled form of Zinpyr-1.

103 tion, with the exception of acetaldehyde and diacetyl formation.

104 ster, we evaluated a yeast-emitted volatile, diacetyl, found at high levels around fermenting fruits

105 than in wild-type controls inhaling 200 ppm diacetyl, further implicating the alpha-dicarbonyl group

106 bearing a 3-TIPS-ethynyl-13-acetyl or a 3,13-diacetyl group exhibit a number of spectral properties r

107 nt C28 sugar unit, which features either 3,4-diacetyl groups or a 3,4-cyclic carbonate group at the r

108 Experimentally, 2,3-carbon-13-labeled diacetyl has a disconnected eigenstate that can store po

109 X-ray and NMR data of the 1,2-diacetyl iduronate methyl ester and the analogous iduron

110 m 3 to 9 progressively enhanced retention of diacetyl in emulsions prepared with both DEY and SOE.

111 -enriched acetate, acetone and C(4)H(6)O(2) (diacetyl) increased.

112 sed by in vivo protein damage, we correlated diacetyl-induced airway damage in mice with immunofluore

113 is, tracheitis, and bronchitis comparable to diacetyl-induced injury.

114 Diacetyl inhalation caused dose-dependent increases in b

115 onyl/l-xylulose reductase (DCXR) metabolizes diacetyl into acetoin, which lacks this alpha-dicarbonyl

116 Diacetyl is a volatile flavour compound that has a chara

117 The attractive odorant diacetyl is detected by the receptor protein ODR-10, whi

118 Diacetyl is directly photoexcitable, and thus, no extran

119 oli attenuated the chemotaxis ability toward diacetyl, isoamyl alcohol, and benzaldehyde when aged.

120 l wall peptide analogue (N(alpha),N(epsilon)-diacetyl-L-Lys-D-Ala-D-Ala) was studied using a 6 T Four

121 vancomycin aglycon (VA), N(alpha),N(epsilon)-diacetyl-L-Lys-D-Ala-D-Ala, and noncovalent complexes of

122 5 (PBP 5) against the classic PBP substrate diacetyl-L-Lys-D-Ala-D-Ala.

123 l-D-Ala-D-Ala and V with N(alpha),N(epsilon)-diacetyl-L-Lys-D-Ala-D-Ala.

124 tra from the noncovalent complex, vancomycin/diacetyl-L-lysyl-D-alanyl-D-alanine, obtained from ESI a

125 alysis of the noncovalent complex vancomycin/diacetyl-L-lysyl-D-alanyl-D-alanine.

126 To mediate diacetyl learning and thus integrate the aversive food c

127 ns in a few bars approached the 8-h REL, and diacetyl levels were close to the lower limit for occupa

128 does not affect the response to the odorant diacetyl mediated by the AWA neurons.

129 anal, pentanal, hexanal, Strecker aldehydes, diacetyl, methyl glyoxal, 3-pentanone and 2-furfural, wh

130 of aromatic neurotoxicants containing a 1,2-diacetyl moiety in their oxidation metabolites.

131 Exposure to the diacetyl molecules in headspace alters gene expression i

132 heme b in the CcO mimic with heme a analogs, diacetyl, monoformyl, and diformyl hemes, that posses el

133 rthermore, ionization of ammonium adducts of diacetyl monoglyceride derivatives in positive-ion mode

134 educe the slope of the restitution relation (diacetyl monoxime and verapamil) prevent the induction o

135 The apparent affinity of ODR-10 for diacetyl observed in human cells is consistent with the

136 integrate the aversive food context with the diacetyl odor, FLP-34 is released from serotonergic neur

137 This study investigates the effect of diacetyl on the satiety hormone, glucagon-like peptide (

138 ants have a specific defect in chemotaxis to diacetyl, one of several odorants detected by the AWA ol

139 Volatile compounds that differ from diacetyl only by the addition of a methyl group (2,3-pen

140 ation of substituted 2-methylquinolines with diacetyl or ethyl pyruvate, under environmentally friend

141 studies, we substitute electron-withdrawing (diacetyl) or -donating (diethyl) groups at the 2- and 4-

142 inant from glucosone while methylglyoxal and diacetyl originated from 1-deoxyglucosone.

143 Under phosphate-sufficient conditions, diacetyl partially suppresses plant production of reacti

144 ch employing Knoevenagel condensation of N,N-diacetyl-piperazine-2,5-dione with different aromatic al

145 in AWA and AWB have a defective response to diacetyl, possibly because of conflicting olfactory inpu

146 r(II) complex of a bis(thiosemicarbazone) of diacetyl, prevents oxidative cell death and acts as a ne

147 ate, which are metabolic precursors used for diacetyl production by certain bacterial species.

148 -ethynyl), 3-TIPS-ethynyl-13-acetyl, or 3,13-diacetyl, progressively causes (1) a redshift in the abs

149 anomeric effect, when compared to the 4O,5N-diacetyl protected systems.

150 Cell surface sugar 5,7-diacetyl pseudaminic acid (Pse5Ac7Ac) is a bacterial ana

151 The T-acetylated at aliphatic-OH and 3,5-diacetyl-R exhibited the most powerful effect in non-enz

152 e attributed to the different expressions of diacetyl receptor odr-10, and the chemotaxis behavior of

153 degrees C within 3h with a maximum level of diacetyl recorded at 6h.

154 d probable relation with pressure influenced diacetyl reductase, acetoin reductase and acetolactate d

155 9 mg/kg for glyoxal, methylglyoxal (MGo) and diacetyl, respectively.

156 tream of the ankyrin repeats domain, but the diacetyl sensitivity is mediated by independent mechanis

157 ut this chimeric channel does not respond to diacetyl stimuli.

158 Using diethyl substitution (pK3 = 5.8) and diacetyl substitution (pK3 = 3.3) in HRP and Mb, we meas

159 ermaphrodites to the food-associated odorant diacetyl, suggesting that sensory modulation may contrib

160 ds were identified within the ONS, including diacetyl (sweet), isoamyl acetate (banana), dimethyl tri

161 of bulk and emulsified CO in the presence of diacetyl tartaric acid ester of monoglycerides (DATEM) a

162 duced with combined use of sodium caseinate, diacetyl tartaric acid esters of mono- and diglycerides

163 Unlike diacetyl tartaric esters of mono- and diacylglycerols (D

164 Diacetyl-tartaric anhydride (DATAN) was used for the sim

165 ounds, 1,2-diacetylbenzene (1,2-DAB) and 1,2-diacetyl tetramethyl tetralin (1,2-DATT), the putative a

166 ording to current and cumulative exposure to diacetyl, the predominant ketone in artificial butter fl

167 side analogue was used: methyl beta-N,N'-[3H]diacetyl-thiochitobioside (Me-[3H]TCB).

168 This ability of diacetyl to reduce satiety signals may contribute to ove

169 day(-1)), acrolein (up to 10 mg day(-1)) and diacetyl (up to 0.5 mg day(-1)), at levels that exceeded

170 Inhaled diacetyl vapors are associated with flavorings-related l

171 Exposure to diacetyl vapors slowed progression of neurodegeneration

172 Introduction of beta-OAc to 4,27-diacetyl-WA (16) at C-15 (37) decreased HSA without affe

173 reasing salt concentration, the retention of diacetyl was decreased, irrespectively of the applied em

174 Diacetyl was detected above the laboratory limit of dete

175 nhalation exposure of the flavoring chemical diacetyl was found to be associated with a disease that

176 o[3,2-b]pyrroles from amines, aldehydes, and diacetyl, we confirmed that iron salts are the most effi

177 Glyoxal, methylglyoxal and diacetyl were found to be formed as metabolites during y

178 express ODR-10 in AWB rather than AWA avoid diacetyl, while maintaining qualitatively normal respons

179 or aversive olfactory learning after pairing diacetyl with the absence of food, but not for appetitiv