ライフサイエンスコーパス: diacetyl

1 likely to encode a receptor for the odorant diacetyl.

2 cetaldehyde, glycidol, acrolein, acetol, and diacetyl.

3 s aromatized with (-)-alpha-pinene than with diacetyl.

4 hyl-2-propene to provide 5-exomethylene-1, 3-diacetyl-1,3-diazacyclohexane 28.

5 in vitro the cleavage of the Pth substrates diacetyl-[14C]lysyl-tRNA and acetyl-[14C]phenylalanyl-tR

6 sure to the alpha-diketone butter flavoring, diacetyl (2,3-butanedione).

7 Flavoring chemicals in e-cigarettes: diacetyl, 2,3-pentanedione, and acetoin in a sample of 5

8 was captured and analyzed for total mass of diacetyl, 2,3-pentanedione, and acetoin, according to OS

9 pentanedione (112, 241, 318, or 354 ppm), or diacetyl (240 ppm) for 6 hours were sacrificed the follo

10 ate 7-acetyl-4-deacetylbaccatin III and 7,13-diacetyl-4-deacetylbaccatin III substrates at C4, sugges

11 accatin III, 7-acetyl-, 13-acetyl-, and 7,13-diacetyl-4-deacetylbaccatin III.

12 hin films of vapor-deposited heptakis (2,3-O-diacetyl-6-O-tertbutyl-dimethylsilyl)-beta-cyclodextrin

13 xtrin family, the sodium salt of octakis(2,3-diacetyl-6-sulfato)-gamma-cyclodextrin (ODAS-gamma CD) h

14 Diacetyl, a known respiratory hazard, along with acetoin

15 f the major flavour compounds (acetaldehyde, diacetyl, acetoin, and 2-butanone) followed a sigmoidal

16 the retention and release characteristics of diacetyl and (-)-alpha-pinene in oil-in-water (o/w) emul

17 Because of the associations between diacetyl and bronchiolitis obliterans and other severe r

18 Glycosylation of the 4-OH groups of the N,N-diacetyl and N-acetyl-N-benzyl glucosamine was also foun

19 quartile of estimated cumulative exposure to diacetyl and the frequency and extent of airway obstruct

20 tivities predominantly target H4 to give the diacetyl and triacetyl species; some acetylation of H2A

21 aimed to determine if the flavoring chemical diacetyl and two other high-priority flavoring chemicals

22 tent carboxonium-pyrenium dications, whereas diacetyl- and dibenzoylpyrenes are diprotonated to give

23 elevation in intracellular Ca2+ levels after diacetyl application.

24 ibitor, MeU-diNAG (4-methylumbelliferyl-N,N'-diacetyl-beta-D-chitobioside).

25 at oral treatment with the therapeutic agent diacetyl-bis(4-methylthiosemicarbazonato)copper(II) [Cu(

26 The hypoxia PET tracer (64)Cu-diacetyl-bis(N(4)-methylthiosemicarbazonate) ((64)Cu-ATS

27 (64)Cu-diacetyl-bis(N(4)-methylthiosemicarbazonate), (64)Cu-ATS

28 oxia demonstrated by PET with (60)Cu-labeled diacetyl-bis(N(4)-methylthiosemicarbazone) ((60)Cu-ATSM)

29 orothymidine ((18)F-FLT), and (61)Cu-labeled diacetyl-bis(N(4)-methylthiosemicarbazone) ((61)Cu-ATSM)

30 mpounds, 2-deoxyglucose (2-DG) and copper(II)diacetyl-bis(N(4)-methylthiosemicarbazone) ((64)Cu-ATSM)

31 c administration of hypoxia-selective (64)Cu-diacetyl-bis(N(4)-methylthiosemicarbazone) ((64)Cu-ATSM)

32 Tumor uptake of copper(II)-diacetyl-bis(N(4)-methylthiosemicarbazone) (copper-ATSM)

33 Copper(II)-diacetyl-bis(N(4)-methylthiosemicarbazone) (copper-ATSM)

34 Cu-Diacetyl-bis(N(4)-methylthiosemicarbazone) (Cu-ATSM) is

35 We showed previously that, in vitro, copper-diacetyl-bis(N(4)-methylthiosemicarbazone) (Cu-ATSM) upt

36 within tumors, such as (60/62/64)Cu-labeled diacetyl-bis(N(4)-methylthiosemicarbazone) and (18)F-flu

37 bis(N-4-methyl-3-thiosemicarbazone) and zinc diacetyl-bis(N-4-methyl-3-thiosemicarbazide) display the

38 Diacetyl-bis(N-4-methyl-3-thiosemicarbazone) and zinc di

39 zomycin arabinoside [(18)F-FAZA], and (64)Cu-diacetyl-bis(N4-methylsemicarbazone) [(64)Cu-ATSM]) in a

40 DR1 expression on the accumulation of (64)Cu-diacetyl-bis(N4-methylthiosemicarbazone) ((64)Cu-ATSM) a

41 The PET tracer copper(II)-diacetyl-bis(N4-methylthiosemicarbazone) ((64)Cu-ATSM) h

42 in-arabinofuranoside ((18)F-FAZA) and (64)Cu-diacetyl-bis(N4-methylthiosemicarbazone) ((64)Cu-ATSM) h

43 We have evaluated Cu-diacetyl-bis(N4-methylthiosemicarbazone) (Cu-ATSM), an e

44 ous promoter directs behavioral responses to diacetyl, but not to another odorant detected by the AWA

45 Chemotaxis toward one such odorant, diacetyl (butanedione), requires the function of a seven

46 rologous system and show that it responds to diacetyl by activation of a G protein signaling pathway.

47 cited aliphatic ketones, such as acetone and diacetyl, can be used as promising low-cost radical init

48 The reactive alpha-dicarbonyl group in diacetyl causes protein damage in vitro.

49 r serpentine receptors related to the ODR-10 diacetyl chemoreceptor is very large, with at least 197

50 The disaccharide N,N'-diacetyl-chitobiose, (GlcNAc)2, is critical in chitin di

51 This unexpected susceptibility to diacetyl chloramphenicol was wholly or partly the conseq

52 chaeta aurantia was nearly as susceptible to diacetyl chloramphenicol, the product of chloramphenicol

53 of the presence of either chloramphenicol or diacetyl chloramphenicol.

54 he treatment with lees for ethyl propionate, diacetyl, cis-3-hexenol, acetic acid, benzyl alcohol, an

55 served in human cells is consistent with the diacetyl concentration ranges that allow efficient nemat

56 ethyl-2-furfural, glyoxal, methylglyoxal and diacetyl concentrations were determined to form a multir

57 ultaneous binding and recognition of diverse diacetyl-containing peptides by BRD4.

58 Ab initio asymmetric syntheses of methyl N,O-diacetyl-D-3-epi-daunosaminide and methyl N,O-diacetyl-D

59 ysis, and acetate protection gave methyl N,O-diacetyl-D-3-epi-daunosaminide and methyl N,O-diacetyl-D

60 iacetyl-D-3-epi-daunosaminide and methyl N,O-diacetyl-D-ristosaminide, employing diastereoselective e

61 iacetyl-D-3-epi-daunosaminide and methyl N,O-diacetyl-D-ristosaminide.

62 Glyoxal (GO), methylglyoxal (MGO), diacetyl (DA) and 3-deoxyglucosone (3-DG) were found in

63 Diacetyl decreased proglucagon mRNA and total GLP-1 from

64 9,10-Dimethoxyphenanthrene gives its 3,6-diacetyl derivative in good yield and in large amounts.

65 The ligands were synthesized from the diacetyl derivative of the central linker by a Friedland

66 The precursor diacetyl derivatives were, in turn, prepared by pathways

67 The rapid and robust diacetyl derivatization at low temperatures (e.g., -20 d

68 Critically, diacetyl derivatization enables the differentiation of d

69 ize acyl migration, a facile low temperature diacetyl derivatization to stabilize regiospecificity, a

70 roarylbenzaldehydes with aromatic amines and diacetyl, followed by double intramolecular oxidative ar

71 eaction-based, targetable probe based on the diacetyled form of Zinpyr-1.

72 tion, with the exception of acetaldehyde and diacetyl formation.

73 than in wild-type controls inhaling 200 ppm diacetyl, further implicating the alpha-dicarbonyl group

74 bearing a 3-TIPS-ethynyl-13-acetyl or a 3,13-diacetyl group exhibit a number of spectral properties r

75 Experimentally, 2,3-carbon-13-labeled diacetyl has a disconnected eigenstate that can store po

76 X-ray and NMR data of the 1,2-diacetyl iduronate methyl ester and the analogous iduron

77 m 3 to 9 progressively enhanced retention of diacetyl in emulsions prepared with both DEY and SOE.

78 sed by in vivo protein damage, we correlated diacetyl-induced airway damage in mice with immunofluore

79 is, tracheitis, and bronchitis comparable to diacetyl-induced injury.

80 Diacetyl inhalation caused dose-dependent increases in b

81 onyl/l-xylulose reductase (DCXR) metabolizes diacetyl into acetoin, which lacks this alpha-dicarbonyl

82 Diacetyl is a volatile flavour compound that has a chara

83 The attractive odorant diacetyl is detected by the receptor protein ODR-10, whi

84 l wall peptide analogue (N(alpha),N(epsilon)-diacetyl-L-Lys-D-Ala-D-Ala) was studied using a 6 T Four

85 vancomycin aglycon (VA), N(alpha),N(epsilon)-diacetyl-L-Lys-D-Ala-D-Ala, and noncovalent complexes of

86 5 (PBP 5) against the classic PBP substrate diacetyl-L-Lys-D-Ala-D-Ala.

87 l-D-Ala-D-Ala and V with N(alpha),N(epsilon)-diacetyl-L-Lys-D-Ala-D-Ala.

88 tra from the noncovalent complex, vancomycin/diacetyl-L-lysyl-D-alanyl-D-alanine, obtained from ESI a

89 alysis of the noncovalent complex vancomycin/diacetyl-L-lysyl-D-alanyl-D-alanine.

90 ns in a few bars approached the 8-h REL, and diacetyl levels were close to the lower limit for occupa

91 does not affect the response to the odorant diacetyl mediated by the AWA neurons.

92 of aromatic neurotoxicants containing a 1,2-diacetyl moiety in their oxidation metabolites.

93 heme b in the CcO mimic with heme a analogs, diacetyl, monoformyl, and diformyl hemes, that posses el

94 rthermore, ionization of ammonium adducts of diacetyl monoglyceride derivatives in positive-ion mode

95 educe the slope of the restitution relation (diacetyl monoxime and verapamil) prevent the induction o

96 The apparent affinity of ODR-10 for diacetyl observed in human cells is consistent with the

97 This study investigates the effect of diacetyl on the satiety hormone, glucagon-like peptide (

98 ants have a specific defect in chemotaxis to diacetyl, one of several odorants detected by the AWA ol

99 Volatile compounds that differ from diacetyl only by the addition of a methyl group (2,3-pen

100 studies, we substitute electron-withdrawing (diacetyl) or -donating (diethyl) groups at the 2- and 4-

101 inant from glucosone while methylglyoxal and diacetyl originated from 1-deoxyglucosone.

102 in AWA and AWB have a defective response to diacetyl, possibly because of conflicting olfactory inpu

103 ate, which are metabolic precursors used for diacetyl production by certain bacterial species.

104 -ethynyl), 3-TIPS-ethynyl-13-acetyl, or 3,13-diacetyl, progressively causes (1) a redshift in the abs

105 anomeric effect, when compared to the 4O,5N-diacetyl protected systems.

106 The T-acetylated at aliphatic-OH and 3,5-diacetyl-R exhibited the most powerful effect in non-enz

107 degrees C within 3h with a maximum level of diacetyl recorded at 6h.

108 9 mg/kg for glyoxal, methylglyoxal (MGo) and diacetyl, respectively.

109 tream of the ankyrin repeats domain, but the diacetyl sensitivity is mediated by independent mechanis

110 ut this chimeric channel does not respond to diacetyl stimuli.

111 Using diethyl substitution (pK3 = 5.8) and diacetyl substitution (pK3 = 3.3) in HRP and Mb, we meas

112 ermaphrodites to the food-associated odorant diacetyl, suggesting that sensory modulation may contrib

113 Unlike diacetyl tartaric esters of mono- and diacylglycerols (D

114 ounds, 1,2-diacetylbenzene (1,2-DAB) and 1,2-diacetyl tetramethyl tetralin (1,2-DATT), the putative a

115 ording to current and cumulative exposure to diacetyl, the predominant ketone in artificial butter fl

116 side analogue was used: methyl beta-N,N'-[3H]diacetyl-thiochitobioside (Me-[3H]TCB).

117 This ability of diacetyl to reduce satiety signals may contribute to ove

118 day(-1)), acrolein (up to 10 mg day(-1)) and diacetyl (up to 0.5 mg day(-1)), at levels that exceeded

119 Inhaled diacetyl vapors are associated with flavorings-related l

120 Introduction of beta-OAc to 4,27-diacetyl-WA (16) at C-15 (37) decreased HSA without affe

121 reasing salt concentration, the retention of diacetyl was decreased, irrespectively of the applied em

122 Diacetyl was detected above the laboratory limit of dete

123 nhalation exposure of the flavoring chemical diacetyl was found to be associated with a disease that

124 express ODR-10 in AWB rather than AWA avoid diacetyl, while maintaining qualitatively normal respons